Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CCDC27	148870	broad.mit.edu	37	1	3677920	3677920	+	Missense_Mutation	SNP	G	A	A			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr1:3677920G>A	uc001akv.2	+	5	868	c.787G>A	c.(787-789)GAG>AAG	p.E263K		NM_152492	NP_689705	Q2M243	CCD27_HUMAN	coiled-coil domain containing 27	263	Potential.									skin(1)	1	all_cancers(77;0.0385)|Ovarian(185;0.0634)|Lung NSC(156;0.21)|all_lung(157;0.218)	all_epithelial(116;5.52e-17)|all_lung(118;1.04e-06)|Lung NSC(185;0.000214)|Renal(390;0.00357)|Breast(487;0.00446)|Hepatocellular(190;0.0218)|Lung SC(97;0.0367)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.127)		Epithelial(90;1.11e-38)|OV - Ovarian serous cystadenocarcinoma(86;1.35e-22)|GBM - Glioblastoma multiforme(42;3.46e-16)|Colorectal(212;1.17e-05)|COAD - Colon adenocarcinoma(227;5.76e-05)|Kidney(185;0.00036)|BRCA - Breast invasive adenocarcinoma(365;0.000696)|KIRC - Kidney renal clear cell carcinoma(229;0.00558)|STAD - Stomach adenocarcinoma(132;0.00645)|Lung(427;0.203)		GGAGGAGAGGGAGGCCCTGAA	0.592000													8	71	---	---	---	---	0	0	0.000157383	0	0
FRRS1	391059	broad.mit.edu	37	1	100181191	100181191	+	Missense_Mutation	SNP	G	T	T			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr1:100181191G>T	uc001dsh.1	-	12	1876	c.1274C>A	c.(1273-1275)ACC>AAC	p.T425N		NM_001013660	NP_001013682	Q6ZNA5	FRRS1_HUMAN	stromal cell derived factor receptor 2 homolog	425	Cytochrome b561.|Helical; Name=3; (Potential).				electron transport chain|transport	integral to membrane	ferric-chelate reductase activity|metal ion binding			skin(1)	1		all_epithelial(167;2.09e-06)|all_lung(203;0.000435)|Lung NSC(277;0.00201)		Epithelial(280;0.0718)|all cancers(265;0.126)|COAD - Colon adenocarcinoma(174;0.148)|Lung(183;0.206)		AGCAATGCAGGTGAGGACAGT	0.373000													23	59	---	---	---	---	2.41591e-17	1.80983e-15	0.000720815	1	0
IFI16	3428	broad.mit.edu	37	1	158990261	158990261	+	Missense_Mutation	SNP	G	A	A			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr1:158990261G>A	uc001ftg.2	+	6	1393	c.1103G>A	c.(1102-1104)CGA>CAA	p.R368Q	IFI16_uc010pis.1_Missense_Mutation_p.R312Q	NM_005531	NP_005522	Q16666	IF16_HUMAN	interferon, gamma-inducible protein 16	368	HIN-200 1.				cell proliferation|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|monocyte differentiation|negative regulation of transcription, DNA-dependent|response to virus|transcription, DNA-dependent	cytoplasm|nuclear speck|nucleolus	double-stranded DNA binding|protein binding			ovary(1)	1	all_hematologic(112;0.0429)					TTCTGCTTTCGACTTAGAAAA	0.358000													42	43	---	---	---	---	0	0	0.000319135	0	0
FAM5C	339479	broad.mit.edu	37	1	190129933	190129933	+	Missense_Mutation	SNP	T	G	G			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr1:190129933T>G	uc001gse.1	-	7	1281	c.1049A>C	c.(1048-1050)AAT>ACT	p.N350T	FAM5C_uc010pot.1_Missense_Mutation_p.N248T	NM_199051	NP_950252	Q76B58	FAM5C_HUMAN	family with sequence similarity 5, member C	350						extracellular region				lung(2)|ovary(1)|kidney(1)|skin(1)	5	Prostate(682;0.198)					GCGCTGAAAATTAGAATCCAT	0.353000													4	134	---	---	---	---	0	0	0.000602214	0	0
MIA3	375056	broad.mit.edu	37	1	222825616	222825616	+	Missense_Mutation	SNP	A	C	C			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr1:222825616A>C	uc001hnl.2	+	13	4037	c.4028A>C	c.(4027-4029)AAG>ACG	p.K1343T	MIA3_uc009xea.1_Intron|MIA3_uc001hnm.2_Missense_Mutation_p.K221T	NM_198551	NP_940953	Q5JRA6	MIA3_HUMAN	melanoma inhibitory activity family, member 3	1343	Potential.|Cytoplasmic (Potential).				exocytosis|negative regulation of cell adhesion|negative regulation of cell migration|positive regulation of leukocyte migration|protein transport|wound healing	endoplasmic reticulum membrane|integral to membrane	protein binding			ovary(4)|central_nervous_system(1)	5				GBM - Glioblastoma multiforme(131;0.0199)		GAGAAGGTGAAGTCTGAATGC	0.378000													6	103	---	---	---	---	0	0	0.000274275	0	0
RRP12	23223	broad.mit.edu	37	10	99125892	99125892	+	Missense_Mutation	SNP	T	C	C			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr10:99125892T>C	uc001knf.2	-	29	3629	c.3490A>G	c.(3490-3492)AAG>GAG	p.K1164E	RRP12_uc001kne.2_Missense_Mutation_p.K179E|RRP12_uc009xvl.2_Missense_Mutation_p.K281E|RRP12_uc009xvm.2_Missense_Mutation_p.K882E|RRP12_uc010qou.1_Missense_Mutation_p.K1103E|RRP12_uc009xvn.2_Missense_Mutation_p.K1064E	NM_015179	NP_055994	Q5JTH9	RRP12_HUMAN	ribosomal RNA processing 12 homolog isoform 1	1164						integral to membrane|nuclear membrane|nucleolus	protein binding			ovary(2)|central_nervous_system(1)	3		Colorectal(252;0.162)		Epithelial(162;2.72e-09)|all cancers(201;1.76e-07)		TCCTCCATCTTGTTGCCGTCT	0.597000													5	151	---	---	---	---	0	0	3.59834e-05	0	0
TRPM5	29850	broad.mit.edu	37	11	2433483	2433483	+	Missense_Mutation	SNP	C	G	G			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr11:2433483C>G	uc001lwm.3	-	16	2365	c.2356G>C	c.(2356-2358)GGC>CGC	p.G786R	TRPM5_uc010qxl.1_Missense_Mutation_p.G786R|TRPM5_uc009ydn.2_Missense_Mutation_p.G788R	NM_014555	NP_055370	Q9NZQ8	TRPM5_HUMAN	transient receptor potential cation channel,	786	Cytoplasmic (Potential).					integral to membrane|plasma membrane	receptor activity|voltage-gated ion channel activity			ovary(1)|breast(1)|central_nervous_system(1)|skin(1)	4		Medulloblastoma(188;0.0049)|Breast(177;0.00586)|all_epithelial(84;0.0075)|Ovarian(85;0.0256)|all_neural(188;0.0311)		BRCA - Breast invasive adenocarcinoma(625;0.00147)|LUSC - Lung squamous cell carcinoma(625;0.191)		GTGAAGAAGCCCTGGGAGGGA	0.562000													46	101	---	---	---	---	0	0	0.000781405	0	0
RPL13AP20	387841	broad.mit.edu	37	12	13028751	13028751	+	Missense_Mutation	SNP	G	C	C			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr12:13028751G>C	uc010sho.1	+	1	341	c.319G>C	c.(319-321)GGC>CGC	p.G107R		NR_003932				SubName: Full=Ribosomal protein L13a variant; Flags: Fragment;												0						GGTGTTTGACGGCATCCCACC	0.612000													3	21	---	---	---	---	0	0	0.000602214	0	0
ERGIC2	51290	broad.mit.edu	37	12	29509405	29509405	+	Missense_Mutation	SNP	T	C	C			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr12:29509405T>C	uc001riv.2	-	8	615	c.482A>G	c.(481-483)GAT>GGT	p.D161G	ERGIC2_uc001riw.2_RNA	NM_016570	NP_057654	Q96RQ1	ERGI2_HUMAN	PTX1 protein	161	Lumenal (Potential).				vesicle-mediated transport	endoplasmic reticulum membrane|ER-Golgi intermediate compartment membrane|Golgi apparatus|integral to membrane|nucleus				ovary(1)	1	Lung NSC(12;2.02e-08)|Acute lymphoblastic leukemia(23;0.00885)|all_hematologic(23;0.0155)|Lung SC(9;0.184)				Arsenic trioxide(DB01169)	TGATGAATCATCTTCTCTGTT	0.308000													4	76	---	---	---	---	0	0	0.00024832	0	0
MYO5A	4644	broad.mit.edu	37	15	52605985	52605985	+	Missense_Mutation	SNP	G	A	A			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr15:52605985G>A	uc002aby.2	-	41	5720	c.5476C>T	c.(5476-5478)CCT>TCT	p.P1826S	MYO5A_uc002abx.3_Missense_Mutation_p.P1799S|MYO5A_uc010ugd.1_Missense_Mutation_p.P548S	NM_000259	NP_000250	Q9Y4I1	MYO5A_HUMAN	myosin VA isoform 1	1826					actin filament-based movement|transport	cytoplasm|growth cone|myosin complex|ruffle	actin binding|ATP binding|calmodulin binding|microfilament motor activity			ovary(3)|central_nervous_system(1)	4				all cancers(107;0.0085)|Colorectal(133;0.077)|READ - Rectum adenocarcinoma(133;0.196)		AAGGTGACAGGAAAGATGTGT	0.473000													4	59	---	---	---	---	0	0	0.00024832	0	0
RPL4	6124	broad.mit.edu	37	15	66792426	66792426	+	Missense_Mutation	SNP	G	A	A			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr15:66792426G>A	uc002apv.2	-	9	1062	c.1006C>T	c.(1006-1008)CGC>TGC	p.R336C	SNAPC5_uc002apu.1_5'Flank|RPL4_uc010bhr.2_Missense_Mutation_p.R242C|RPL4_uc002apw.2_Missense_Mutation_p.R242C|RPL4_uc002apx.2_Missense_Mutation_p.R242C	NM_000968	NP_000959	P36578	RL4_HUMAN	ribosomal protein L4	336					endocrine pancreas development|translational elongation|translational termination|viral transcription	cytosolic large ribosomal subunit|nucleolus	protein binding|RNA binding|structural constituent of ribosome				0						GTGTTCCGGCGCATGGTCTTT	0.323000													12	70	---	---	---	---	0	0	0.00010058	0	0
MYH1	4619	broad.mit.edu	37	17	10404034	10404034	+	Silent	SNP	A	G	G			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr17:10404034A>G	uc002gmo.2	-	28	3868	c.3774T>C	c.(3772-3774)GAT>GAC	p.D1258D	uc002gml.1_Intron	NM_005963	NP_005954	P12882	MYH1_HUMAN	myosin, heavy chain 1, skeletal muscle, adult	1258	Potential.					muscle myosin complex|myofibril|myosin filament	actin binding|ATP binding|calmodulin binding|motor activity			ovary(10)|skin(6)|breast(3)|upper_aerodigestive_tract(1)|kidney(1)	21						CACTCAGTTGATCTTCTAGAG	0.468000													4	90	---	---	---	---	0	0	0.00024832	0	0
TCF3	6929	broad.mit.edu	37	19	1627410	1627410	+	Missense_Mutation	SNP	C	T	T			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr19:1627410C>T	uc002ltr.2	-	6	381	c.314G>A	c.(313-315)CGG>CAG	p.R105Q	TCF3_uc002ltt.3_Missense_Mutation_p.R105Q|TCF3_uc002ltq.2_Missense_Mutation_p.R54Q|TCF3_uc002lts.1_Missense_Mutation_p.R21Q	NM_003200	NP_003191	P15923	TFE2_HUMAN	transcription factor 3 isoform E12	105					B cell lineage commitment|B cell lineage commitment|G1 phase of mitotic cell cycle|immunoglobulin V(D)J recombination|muscle cell differentiation|positive regulation of B cell proliferation|positive regulation of cell cycle|positive regulation of muscle cell differentiation|positive regulation of neuron differentiation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter	cytoplasm|nucleus|protein complex|transcription factor complex	bHLH transcription factor binding|DNA binding|E-box binding|identical protein binding|mitogen-activated protein kinase kinase kinase binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding transcription factor activity|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|vitamin D response element binding			lung(2)|breast(2)|ovary(1)|large_intestine(1)|skin(1)	7		Acute lymphoblastic leukemia(61;5.94e-12)|all_hematologic(61;1.27e-07)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		ATAGGCGCCCCGCTCACCGCT	0.617000			T	PBX1|HLF|TFPT	pre B-ALL								9	11	---	---	---	---	0	0	0.000442599	0	0
MUC16	94025	broad.mit.edu	37	19	9049003	9049003	+	Silent	SNP	T	A	A			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr19:9049003T>A	uc002mkp.2	-	5	32832	c.32628A>T	c.(32626-32628)GGA>GGT	p.G10876G		NM_024690	NP_078966	Q8WXI7	MUC16_HUMAN	mucin 16	10878	Thr-rich.|Extracellular (Potential).				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			lung(30)|ovary(15)|breast(8)|large_intestine(1)|skin(1)|prostate(1)|pancreas(1)	57						GGGTCACTACTCCTGGTACCT	0.478000													14	110	---	---	---	---	0	0	0.000151284	0	0
LOC96610	96610	broad.mit.edu	37	22	22661187	22661187	+	RNA	SNP	G	A	A			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr22:22661187G>A	uc011aim.1	+	27		c.1613G>A			LOC96610_uc011aiq.1_RNA|LOC96610_uc011aip.1_Intron|LOC96610_uc010gto.2_RNA					Parts of antibodies, mostly variable regions.												0						CCCCCACCCCGTCATGTACAG	0.413000													11	22	---	---	---	---	0	0	0.000978159	0	0
LOC96610	96610	broad.mit.edu	37	22	22661208	22661208	+	RNA	SNP	C	T	T			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr22:22661208C>T	uc011aim.1	+	27		c.1634C>T			LOC96610_uc011aiq.1_RNA|LOC96610_uc011aip.1_RNA|LOC96610_uc010gto.2_RNA					Parts of antibodies, mostly variable regions.												0						CTGAATCATGCAGAATTTGAA	0.408000													13	27	---	---	---	---	0	0	0.000219431	0	0
HCG4	54435	broad.mit.edu	37	6	29761774	29761774	+	5'Flank	SNP	G	C	C			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr6:29761774G>C	uc003nns.2	-						uc003nnt.2_Intron|uc011dma.1_RNA	NR_002139				Homo sapiens clone HCG IV.9 unknown mRNA.												0						tcctcagcaggattggtgcaa	0.005000													2	10	---	---	---	---	0	0	6.4e-05	0	0
ATF6B	1388	broad.mit.edu	37	6	32083526	32083526	+	Missense_Mutation	SNP	T	C	C			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr6:32083526T>C	uc003nzn.2	-	18	2135	c.2102A>G	c.(2101-2103)AAT>AGT	p.N701S	TNXB_uc010jts.1_Intron|ATF6B_uc003nzm.1_Intron|ATF6B_uc003nzo.2_Missense_Mutation_p.N698S	NM_004381	NP_004372	Q99941	ATF6B_HUMAN	activating transcription factor 6 beta isoform	701	Lumenal (Potential).				response to unfolded protein|signal transduction	endoplasmic reticulum membrane|integral to membrane|nucleus	protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0						TCAGGGATGATTGAGGTAGAG	0.612000													5	113	---	---	---	---	0	0	0.000602214	0	0
ABCC10	89845	broad.mit.edu	37	6	43400340	43400340	+	Missense_Mutation	SNP	G	T	T			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr6:43400340G>T	uc003ouy.1	+	3	837	c.622G>T	c.(622-624)GAT>TAT	p.D208Y	ABCC10_uc003ouz.1_Missense_Mutation_p.D165Y	NM_033450	NP_258261	Q5T3U5	MRP7_HUMAN	ATP-binding cassette, sub-family C, member 10	208				D -> E (in Ref. 1; AAK39642).		integral to membrane|plasma membrane	ATP binding|ATPase activity, coupled to transmembrane movement of substances			ovary(6)|central_nervous_system(1)	7	all_lung(25;0.00536)		Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.0152)|OV - Ovarian serous cystadenocarcinoma(102;0.0804)			CCTGCCCGAGGATCAAGAACC	0.637000													18	135	---	---	---	---	1.99824e-07	1.37718e-05	0.000566183	1	0
ALG13	79868	broad.mit.edu	37	X	110951444	110951444	+	Silent	SNP	T	C	C			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chrX:110951444T>C	uc011msy.1	+	4	607	c.573T>C	c.(571-573)GCT>GCC	p.A191A	ALG13_uc011msw.1_Silent_p.A113A|ALG13_uc011msx.1_Silent_p.A87A|ALG13_uc011msz.1_Silent_p.A113A|ALG13_uc011mta.1_Silent_p.A87A|ALG13_uc011mtb.1_Silent_p.A87A			Q9NP73	ALG13_HUMAN	SubName: Full=Asparagine-linked glycosylation 13 homolog (S. cerevisiae);	191					dolichol-linked oligosaccharide biosynthetic process|lipid glycosylation|post-translational protein modification|protein N-linked glycosylation via asparagine	endoplasmic reticulum membrane	carbohydrate binding|N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity			lung(1)	1						CTTGCCACGCTTTTTTTCCTC	0.483000													3	84	---	---	---	---	0	0	0.00024832	0	0
KCNN3	3782	broad.mit.edu	37	1	154842331	154842333	+	In_Frame_Del	DEL	TGC	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr1:154842331_154842333delTGC	uc001ffp.2	-	1	422_424	c.108_110delGCA	c.(106-111)CAGCAA>CAA	p.36_37QQ>Q	KCNN3_uc009wox.1_In_Frame_Del_p.36_37QQ>Q	NM_002249	NP_002240	Q9UGI6	KCNN3_HUMAN	small conductance calcium-activated potassium	36_37	Poly-Gln.					integral to membrane	calmodulin binding			lung(1)	1	all_lung(78;2.29e-27)|all_hematologic(923;0.088)|Hepatocellular(266;0.108)|all_neural(408;0.245)		BRCA - Breast invasive adenocarcinoma(34;0.00819)			ctgctgctgttgctgctgctgct	0.236													3	6	---	---	---	---					
Unknown	0	broad.mit.edu	37	12	116030327	116030327	+	IGR	DEL	T	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr12:116030327delT								TBX3 (908358 upstream) : MED13L (366056 downstream)																							ctccattttcTTTTTTTTTTT	0.229													2	4	---	---	---	---					
LOC284232	284232	broad.mit.edu	37	13	19420047	19420053	+	RNA	DEL	TTCGTAT	-	-	rs117180361	by1000genomes	TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr13:19420047_19420053delTTCGTAT	uc010tcj.1	-	1		c.26057_26063delATACGAA				NR_027995				Homo sapiens ankyrin repeat domain 20 family, member A2 pseudogene (LOC284232), non-coding RNA.												0						ATAACATTTCTTCGTATTTTATATTTT	0.246													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	17	18304008	18304008	+	5'Flank	DEL	G	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr17:18304008delG	uc010vxw.1	-						uc002gto.2_5'Flank					DQ589132																		CTGGACGCCTGGGGTGGCCAC	0.592													4	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	17	44324687	44324687	+	IGR	DEL	T	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr17:44324687delT								KIAA1267 (21970 upstream) : ARL17B (39176 downstream)																							AGAAAATGACTTTTTTTTTTA	0.313													7	46	---	---	---	---					
Unknown	0	broad.mit.edu	37	19	3131445	3131446	+	IGR	DEL	AC	-	-	rs66993077		TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr19:3131445_3131446delAC								GNA11 (9993 upstream) : GNA15 (4745 downstream)																							aaaaaaaaaaacaaaaaaaaaa	0.347													5	9	---	---	---	---					
BCL11A	53335	broad.mit.edu	37	2	60688968	60688969	+	Frame_Shift_Ins	INS	-	G	G			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr2:60688968_60688969insG	uc002sae.1	-	4	1306_1307	c.1078_1079insC	c.(1078-1080)CTCfs	p.L360fs	BCL11A_uc002sab.2_Frame_Shift_Ins_p.L360fs|BCL11A_uc002sac.2_Intron|BCL11A_uc010ypi.1_Intron|BCL11A_uc010ypj.1_Frame_Shift_Ins_p.L326fs|BCL11A_uc002sad.1_Frame_Shift_Ins_p.L208fs|BCL11A_uc002saf.1_Frame_Shift_Ins_p.L326fs	NM_022893	NP_075044	Q9H165	BC11A_HUMAN	B-cell CLL/lymphoma 11A isoform 1	360	Pro-rich.				negative regulation of axon extension|negative regulation of collateral sprouting|negative regulation of dendrite development|positive regulation of collateral sprouting|positive regulation of neuron projection development|positive regulation of transcription from RNA polymerase II promoter|protein sumoylation|regulation of dendrite development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|cytoplasm|nucleus|nucleus	nucleic acid binding|protein heterodimerization activity|protein homodimerization activity|zinc ion binding			central_nervous_system(6)|breast(3)|ovary(2)|skin(2)	13			LUSC - Lung squamous cell carcinoma(5;9.29e-08)|Lung(5;1.34e-06)|Epithelial(17;0.0562)|all cancers(80;0.199)			CAGAGGAGGGAGGGGGGGCGTC	0.634			T	IGH@	B-CLL								8	139	---	---	---	---					
Unknown	0	broad.mit.edu	37	4	46725772	46725772	+	IGR	DEL	G	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr4:46725772delG								GABRA2 (333351 upstream) : COX7B2 (11077 downstream)																							tttttttcttggttttttttt	0.338													4	8	---	---	---	---					
HLA-DRB5	3127	broad.mit.edu	37	6	32557612	32557612	+	5'Flank	DEL	G	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr6:32557612delG	uc003obk.3	-						HLA-DRB1_uc003obp.3_5'Flank	NM_002125	NP_002116	Q30154	DRB5_HUMAN	major histocompatibility complex, class II, DR						antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|immune response	endoplasmic reticulum membrane|Golgi apparatus|integral to membrane|late endosome membrane|lysosomal membrane|MHC class II protein complex					0						CCAAGTTATAGGGAGGAAGTT	0.507													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	7	57659470	57659471	+	IGR	DEL	TA	-	-	rs79867563	by1000genomes	TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr7:57659470_57659471delTA								ZNF716 (126205 upstream) : None (None downstream)																							GCGTTGATCTTACAGTCTGGTG	0.371													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	8	4985367	4985367	+	IGR	DEL	T	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr8:4985367delT								CSMD1 (133039 upstream) : None (None downstream)																							ctgacgcttcttttttttttt	0.224													4	2	---	---	---	---					
TTC16	158248	broad.mit.edu	37	9	130487098	130487098	+	Frame_Shift_Del	DEL	T	-	-			TCGA-EM-A2CJ-01A-11D-A17V-08	TCGA-EM-A2CJ-10A-01D-A17V-08									Somatic	Phase_I	Capture				Illumina GAIIx	d71fe053-8273-4eaa-963a-3404ac0e5d83	45f2c6ed-96be-4e86-8e93-1eb61a6a09ac	g.chr9:130487098delT	uc004brq.1	+	9	1248	c.1181delT	c.(1180-1182)CTGfs	p.L394fs	PTRH1_uc011mah.1_5'UTR|TTC16_uc011mai.1_Frame_Shift_Del_p.L381fs|TTC16_uc004brr.1_Intron|TTC16_uc010mxn.1_5'UTR	NM_144965	NP_659402	Q8NEE8	TTC16_HUMAN	tetratricopeptide repeat domain 16	394	TPR 7.						binding				0						GCGCTGGCGCTGAGCCCTCAG	0.682													15	14	---	---	---	---					
