Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
DNAJC16	23341	broad.mit.edu	37	1	15894410	15894410	+	Missense_Mutation	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:15894410G>A	uc001aws.2	+	15	2207	c.2087G>A	c.(2086-2088)GGT>GAT	p.G696D	DNAJC16_uc001awt.2_Missense_Mutation_p.G384D|DNAJC16_uc001awu.2_RNA	NM_015291	NP_056106	Q9Y2G8	DJC16_HUMAN	DnaJ (Hsp40) homolog, subfamily C, member 16	696	Extracellular (Potential).				cell redox homeostasis|protein folding	integral to membrane	heat shock protein binding|unfolded protein binding			urinary_tract(1)|lung(1)|kidney(1)	3		Colorectal(325;0.00108)|Renal(390;0.00145)|Breast(348;0.00173)|all_lung(284;0.00459)|Lung NSC(340;0.00499)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0798)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;9.18e-07)|COAD - Colon adenocarcinoma(227;4.5e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000133)|KIRC - Kidney renal clear cell carcinoma(229;0.00262)|STAD - Stomach adenocarcinoma(313;0.00774)|READ - Rectum adenocarcinoma(331;0.0657)		GACTACACTGGTTATGTACTG	0.443000													24	84					0	0	0.069288	0	0
BAI2	576	broad.mit.edu	37	1	32203282	32203282	+	Silent	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:32203282G>A	uc001btn.2	-	19	3201	c.2847C>T	c.(2845-2847)ACC>ACT	p.T949T	BAI2_uc001btm.2_5'Flank|BAI2_uc001btp.1_5'Flank|BAI2_uc010ogn.1_5'Flank|BAI2_uc010ogo.1_Silent_p.T591T|BAI2_uc010ogp.1_Silent_p.T882T|BAI2_uc010ogq.1_Silent_p.T949T|BAI2_uc001bto.2_Silent_p.T949T	NM_001703	NP_001694	O60241	BAI2_HUMAN	brain-specific angiogenesis inhibitor 2	949	Helical; Name=1; (Potential).				negative regulation of angiogenesis|neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			lung(5)|breast(4)|ovary(2)|central_nervous_system(1)|skin(1)	13		Myeloproliferative disorder(586;0.0255)|Ovarian(437;0.0606)|all_neural(195;0.0837)|Breast(348;0.174)		STAD - Stomach adenocarcinoma(196;0.0557)		TGGCGAGCAGGGTGAGCAGCG	0.667000													16	28					0	0	0.033300	0	0
LEPROT	54741	broad.mit.edu	37	1	65895651	65895651	+	Silent	SNP	C	A	A	rs147651845	byFrequency	TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:65895651C>A	uc001dcf.2	+	3	288	c.199C>A	c.(199-201)CGG>AGG	p.R67R	LEPR_uc001dcg.2_Intron|LEPR_uc001dch.2_Intron|LEPR_uc001dci.2_Intron|LEPR_uc009waq.2_Intron|LEPROT_uc009wap.2_Silent_p.R76R	NM_017526	NP_059996	O15243	OBRG_HUMAN	leptin receptor gene-related protein	67						endosome membrane|Golgi membrane|integral to plasma membrane					0				OV - Ovarian serous cystadenocarcinoma(397;0.00722)|KIRC - Kidney renal clear cell carcinoma(1967;0.094)		TAGTGCCTGTCGGGAACTGGC	0.453000													14	161					0.000151284	0.000163387	0.105934	1	0
ABCA4	24	broad.mit.edu	37	1	94502837	94502837	+	Missense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:94502837C>A	uc001dqh.2	-	25	3781	c.3677G>T	c.(3676-3678)GGT>GTT	p.G1226V		NM_000350	NP_000341	P78363	ABCA4_HUMAN	ATP-binding cassette, sub-family A member 4	1226	Cytoplasmic.				phototransduction, visible light|visual perception	integral to plasma membrane|membrane fraction	ATP binding|ATPase activity, coupled to transmembrane movement of substances			ovary(4)|skin(4)|central_nervous_system(2)|upper_aerodigestive_tract(1)|breast(1)	12		all_lung(203;0.000757)|Lung NSC(277;0.00335)		all cancers(265;0.00432)|GBM - Glioblastoma multiforme(16;0.00715)|Epithelial(280;0.171)		AAGTTCTTGACCAATGCACTC	0.478000													13	56					1.61879e-10	1.82114e-10	0.093190	1	0
KCNA2	3737	broad.mit.edu	37	1	111146524	111146524	+	Missense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:111146524C>A	uc001dzu.2	-	2	1377	c.881G>T	c.(880-882)CGT>CTT	p.R294L	KCNA2_uc009wfv.1_Missense_Mutation_p.R294L|KCNA2_uc009wfw.2_Missense_Mutation_p.R294L	NM_004974	NP_004965	P16389	KCNA2_HUMAN	potassium voltage-gated channel, shaker-related	294	Helical; Voltage-sensor; Name=Segment S4; (Potential).					juxtaparanode region of axon|voltage-gated potassium channel complex	delayed rectifier potassium channel activity			ovary(1)	1		all_cancers(81;5.55e-06)|all_epithelial(167;1.87e-05)|all_lung(203;0.000199)|Lung NSC(277;0.000398)		Colorectal(144;0.00878)|Lung(183;0.0234)|all cancers(265;0.0492)|Epithelial(280;0.0529)|COAD - Colon adenocarcinoma(174;0.131)|LUSC - Lung squamous cell carcinoma(189;0.133)|READ - Rectum adenocarcinoma(129;0.191)		CCGGATGACACGGAGGATGGC	0.537000													28	52					5.60225e-13	6.57655e-13	0.144211	1	0
SPAG17	200162	broad.mit.edu	37	1	118535132	118535132	+	Missense_Mutation	SNP	A	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:118535132A>T	uc001ehk.2	-	36	5386	c.5318T>A	c.(5317-5319)GTC>GAC	p.V1773D		NM_206996	NP_996879	Q6Q759	SPG17_HUMAN	sperm associated antigen 17	1773						cilium|flagellar axoneme|microtubule				upper_aerodigestive_tract(2)|ovary(2)|large_intestine(1)|skin(1)	6	Esophageal squamous(2;0.0106)	all_cancers(81;0.0204)|all_lung(203;9.46e-05)|Lung NSC(69;0.000675)|all_epithelial(167;0.01)		Lung(183;0.0858)		ATTCTTTATGACCTCATGCTG	0.473000													22	65					0	0	0.062417	0	0
FMO4	2329	broad.mit.edu	37	1	171303684	171303684	+	Missense_Mutation	SNP	T	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:171303684T>C	uc001gho.2	+	8	1179	c.962T>C	c.(961-963)ATT>ACT	p.I321T		NM_002022	NP_002013	P31512	FMO4_HUMAN	flavin containing monooxygenase 4	321					xenobiotic metabolic process	integral to membrane|intrinsic to endoplasmic reticulum membrane|microsome	flavin adenine dinucleotide binding|flavin-containing monooxygenase activity|NADP binding			kidney(2)|skin(1)	3	all_cancers(6;3.9e-08)|all_hematologic(923;0.088)|Acute lymphoblastic leukemia(37;0.181)					GAAGAAAACATTGATGTTGTG	0.368000													28	44					0	0	0.116897	0	0
CEP350	9857	broad.mit.edu	37	1	180063597	180063597	+	Missense_Mutation	SNP	A	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:180063597A>T	uc001gnt.2	+	34	8740	c.8357A>T	c.(8356-8358)CAG>CTG	p.Q2786L	CEP350_uc009wxl.2_Missense_Mutation_p.Q2785L|CEP350_uc001gnv.2_Missense_Mutation_p.Q921L|CEP350_uc001gnw.1_Missense_Mutation_p.Q543L|CEP350_uc001gnx.1_Missense_Mutation_p.Q543L	NM_014810	NP_055625	Q5VT06	CE350_HUMAN	centrosome-associated protein 350	2786						centrosome|nucleus|spindle				ovary(4)	4						CTTAGCAATCAGGAGCTTCTT	0.388000													15	26					0	0	0.119110	0	0
OR2M3	127062	broad.mit.edu	37	1	248367073	248367073	+	Missense_Mutation	SNP	G	A	A	rs138010167		TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:248367073G>A	uc010pzg.1	+	1	704	c.704G>A	c.(703-705)CGC>CAC	p.R235H		NM_001004689	NP_001004689	Q8NG83	OR2M3_HUMAN	olfactory receptor, family 2, subfamily M,	235	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|skin(1)	2	all_cancers(71;0.000149)|all_epithelial(71;1.27e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0245)			GAGGGTCGTCGCAAAGCTTTT	0.468000													5	232					0	0	0.014758	0	0
TLL2	7093	broad.mit.edu	37	10	98136535	98136535	+	Missense_Mutation	SNP	C	A	A	rs150738442		TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr10:98136535C>A	uc001kml.1	-	18	2588	c.2362G>T	c.(2362-2364)GCG>TCG	p.A788S		NM_012465	NP_036597	Q9Y6L7	TLL2_HUMAN	tolloid-like 2 precursor	788	CUB 4.				cell differentiation|multicellular organismal development|proteolysis	extracellular region	calcium ion binding|metalloendopeptidase activity|zinc ion binding			ovary(1)|pancreas(1)|skin(1)	3		Colorectal(252;0.0846)		Epithelial(162;1.51e-07)|all cancers(201;7.59e-06)		TTGGGGCTCGCCAGGGTCCCC	0.567000													30	60					7.01153e-11	7.97101e-11	0.125774	1	0
SUFU	51684	broad.mit.edu	37	10	104353417	104353417	+	Missense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr10:104353417C>A	uc001kvy.1	+	5	768	c.622C>A	c.(622-624)CTA>ATA	p.L208I	SUFU_uc001kvw.1_Missense_Mutation_p.L208I|SUFU_uc001kvx.2_Missense_Mutation_p.L208I	NM_016169	NP_057253	Q9UMX1	SUFU_HUMAN	suppressor of fused	208					negative regulation of transcription from RNA polymerase II promoter|proteolysis|skeletal system development	cytoplasm|nucleus	identical protein binding|protein binding|signal transducer activity|transcription corepressor activity|transcription factor binding			central_nervous_system(4)|skin(2)|breast(1)	7		Colorectal(252;0.207)		Epithelial(162;1.36e-08)|all cancers(201;3.81e-07)|BRCA - Breast invasive adenocarcinoma(275;0.242)		CACTGAAGAGCTACACTCAGC	0.607000			D|F|S		medulloblastoma	medulloblastoma			Medulloblastoma_associated_with_Germline_SUFU_Mutation				29	27					3.86903e-22	4.74835e-22	0.054565	1	0
POLR2L	5441	broad.mit.edu	37	11	840428	840428	+	Silent	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr11:840428G>A	uc001lsc.2	-	2	169	c.148C>T	c.(148-150)CTG>TTG	p.L50L	TSPAN4_uc001lsd.1_5'Flank|TSPAN4_uc001lse.1_5'Flank|TSPAN4_uc001lsf.1_5'Flank|TSPAN4_uc001lsg.1_5'Flank|TSPAN4_uc001lsh.1_5'Flank	NM_021128	NP_066951	P62875	RPAB5_HUMAN	DNA directed RNA polymerase II polypeptide L	50					mRNA capping|nuclear mRNA splicing, via spliceosome|positive regulation of viral transcription|protein phosphorylation|regulation of transcription from RNA polymerase I promoter|termination of RNA polymerase III transcription|transcription elongation from RNA polymerase II promoter|transcription elongation from RNA polymerase III promoter|transcription initiation from RNA polymerase II promoter|transcription-coupled nucleotide-excision repair|viral reproduction	DNA-directed RNA polymerase II, core complex	DNA binding|DNA-directed RNA polymerase activity|zinc ion binding				0		all_cancers(49;2.31e-08)|all_epithelial(84;3.72e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.179)|all_lung(207;0.227)		all cancers(45;4.1e-25)|Epithelial(43;3.15e-24)|BRCA - Breast invasive adenocarcinoma(625;4.23e-05)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)		ACGTGGGCCAGCAGCATCCGG	0.637000													42	103					0	0	0.124865	0	0
SAAL1	113174	broad.mit.edu	37	11	18101957	18101957	+	Missense_Mutation	SNP	C	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr11:18101957C>G	uc001mnq.2	-	12	1464	c.1414G>C	c.(1414-1416)GTT>CTT	p.V472L	SAAL1_uc001mnr.2_Missense_Mutation_p.V471L|SAAL1_uc001mns.2_RNA|SAAL1_uc009yhf.2_Missense_Mutation_p.V474L	NM_138421	NP_612430	Q96ER3	SAAL1_HUMAN	serum amyloid A-like 1	472					acute-phase response	extracellular region	binding				0						TAAGTCTGAACCTTCAAACTT	0.318000													15	44					0	0	0.132662	0	0
ARRB1	408	broad.mit.edu	37	11	74979954	74979954	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr11:74979954C>T	uc001owe.1	-	14	1294	c.1072G>A	c.(1072-1074)GAG>AAG	p.E358K	ARRB1_uc001owf.1_Missense_Mutation_p.E350K	NM_004041	NP_004032	P49407	ARRB1_HUMAN	arrestin beta 1 isoform A	358	Interaction with TRAF6.				G-protein coupled receptor internalization|histone H4 acetylation|negative regulation of interleukin-6 production|negative regulation of interleukin-8 production|negative regulation of NF-kappaB transcription factor activity|negative regulation of protein ubiquitination|platelet activation|positive regulation of ERK1 and ERK2 cascade|positive regulation of histone acetylation|positive regulation of Rho protein signal transduction|positive regulation of transcription from RNA polymerase II promoter|post-Golgi vesicle-mediated transport|proteasomal ubiquitin-dependent protein catabolic process|protein transport|protein ubiquitination|signal transduction|stress fiber assembly|transcription from RNA polymerase II promoter	chromatin|coated pit|cytoplasmic vesicle membrane|cytosol|Golgi membrane|lysosomal membrane|membrane fraction|nucleus|plasma membrane|pseudopodium|soluble fraction	angiotensin receptor binding|enzyme inhibitor activity|GTPase activator activity|insulin-like growth factor receptor binding|transcription factor binding|transcription regulatory region DNA binding|ubiquitin protein ligase binding			breast(2)	2						GGGGGTTCCTCTTTGGGCTTG	0.622000													27	55					0	0	0.144211	0	0
GAB2	9846	broad.mit.edu	37	11	77934564	77934564	+	Silent	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr11:77934564G>A	uc001ozh.2	-	6	1461	c.1461C>T	c.(1459-1461)GAC>GAT	p.D487D	GAB2_uc001ozg.2_Silent_p.D449D	NM_080491	NP_536739	Q9UQC2	GAB2_HUMAN	GRB2-associated binding protein 2 isoform a	487					osteoclast differentiation|phosphatidylinositol-mediated signaling|positive regulation of cell proliferation|positive regulation of mast cell degranulation	cytosol|plasma membrane	phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-3,4-bisphosphate binding|transmembrane receptor protein tyrosine kinase adaptor activity			ovary(5)|lung(1)	6	all_cancers(14;3.31e-18)|all_epithelial(13;5.3e-21)|Breast(9;5.6e-16)|Ovarian(111;0.152)		OV - Ovarian serous cystadenocarcinoma(8;1.58e-23)			AGCCAAGTGAGTCAAAGTGAT	0.557000													66	136					0	0	0.139131	0	0
CASP5	838	broad.mit.edu	37	11	104879534	104879534	+	Missense_Mutation	SNP	T	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr11:104879534T>G	uc010rva.1	-	2	213	c.181A>C	c.(181-183)AAA>CAA	p.K61Q	CASP5_uc010ruz.1_Missense_Mutation_p.K74Q|CASP5_uc010rvb.1_Intron|CASP5_uc010rvc.1_Intron|CASP5_uc009yxh.2_Intron|CASP5_uc010rvd.1_Intron	NM_004347	NP_004338	P51878	CASP5_HUMAN	caspase 5 isoform a precursor	61	CARD.				apoptosis|cellular response to mechanical stimulus|proteolysis|regulation of apoptosis	intracellular	cysteine-type endopeptidase activity|protein binding			ovary(2)|lung(1)	3		Acute lymphoblastic leukemia(157;0.000967)|all_hematologic(158;0.0017)|Melanoma(852;0.0047)		BRCA - Breast invasive adenocarcinoma(274;0.000943)|Epithelial(105;0.0104)|all cancers(92;0.042)		CCAGTCTTACTTTTTACACTG	0.388000													20	33					0	0	0.055883	0	0
KDM5A	5927	broad.mit.edu	37	12	404935	404935	+	Missense_Mutation	SNP	G	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr12:404935G>C	uc001qif.1	-	26	4622	c.4259C>G	c.(4258-4260)CCT>CGT	p.P1420R	KDM5A_uc001qie.1_Missense_Mutation_p.P1425R	NM_001042603	NP_001036068	P29375	KDM5A_HUMAN	retinoblastoma binding protein 2 isoform 1	1420					chromatin modification|multicellular organismal development|positive regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter	cytoplasm|nucleolus	DNA binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|sequence-specific DNA binding transcription factor activity|zinc ion binding			skin(2)|ovary(1)	3						GCTCTTCCGAGGTTGTTTCCT	0.408000			T 	NUP98	AML								48	79					0	0	0.131918	0	0
AEBP2	121536	broad.mit.edu	37	12	19615463	19615463	+	Missense_Mutation	SNP	G	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr12:19615463G>C	uc001ref.2	+	2	717	c.691G>C	c.(691-693)GAT>CAT	p.D231H	AEBP2_uc001ree.2_Missense_Mutation_p.D231H|AEBP2_uc001reg.1_Missense_Mutation_p.D2H	NM_001114176	NP_001107648	Q6ZN18	AEBP2_HUMAN	AE binding protein 2 isoform b	231	Ser-rich.|Interaction with RBBP4.				chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	ESC/E(Z) complex	DNA binding|zinc ion binding			ovary(1)	1	Acute lymphoblastic leukemia(4;0.000455)|all_hematologic(4;0.00804)|Esophageal squamous(101;0.143)					TACTATAATGGATGTAGACAG	0.328000													11	16					0	0	0.093190	0	0
PFKM	5213	broad.mit.edu	37	12	48538849	48538849	+	Silent	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr12:48538849C>A	uc001rrc.2	+	21	2198	c.2028C>A	c.(2026-2028)GCC>GCA	p.A676A	PFKM_uc001rra.1_Silent_p.A361A|PFKM_uc001rrb.1_Silent_p.A747A|PFKM_uc001rrd.2_Silent_p.A361A|PFKM_uc001rre.1_Silent_p.A676A|PFKM_uc001rrg.1_Silent_p.A645A	NM_000289	NP_000280	P08237	K6PF_HUMAN	phosphofructokinase, muscle	676					fructose 6-phosphate metabolic process|glycolysis|muscle cell homeostasis	6-phosphofructokinase complex|apical plasma membrane	6-phosphofructokinase activity|ATP binding|identical protein binding|kinase binding|metal ion binding|protein C-terminus binding			ovary(2)|upper_aerodigestive_tract(1)|kidney(1)	4						GGAATTTTGCCACTAAGATGG	0.473000													32	61					1.26612e-14	1.51934e-14	0.059317	1	0
NCKAP1L	3071	broad.mit.edu	37	12	54903761	54903761	+	Missense_Mutation	SNP	T	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr12:54903761T>G	uc001sgc.3	+	7	806	c.727T>G	c.(727-729)TCA>GCA	p.S243A	NCKAP1L_uc010sox.1_Translation_Start_Site|NCKAP1L_uc010soy.1_Missense_Mutation_p.S193A	NM_005337	NP_005328	P55160	NCKPL_HUMAN	NCK-associated protein 1-like	243					actin polymerization-dependent cell motility|B cell homeostasis|B cell receptor signaling pathway|cortical actin cytoskeleton organization|erythrocyte development|maintenance of cell polarity|myeloid cell homeostasis|negative regulation of apoptosis|negative regulation of interleukin-17 production|negative regulation of interleukin-6 production|negative regulation of myosin-light-chain-phosphatase activity|neutrophil chemotaxis|positive regulation of actin filament polymerization|positive regulation of B cell differentiation|positive regulation of B cell proliferation|positive regulation of CD4-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of cell adhesion mediated by integrin|positive regulation of erythrocyte differentiation|positive regulation of gamma-delta T cell differentiation|positive regulation of neutrophil chemotaxis|positive regulation of phagocytosis, engulfment|positive regulation of T cell proliferation|protein complex assembly|response to drug|T cell homeostasis	cytosol|integral to plasma membrane|membrane fraction|SCAR complex	protein complex binding|protein kinase activator activity|Rac GTPase activator activity			ovary(3)|central_nervous_system(1)	4						CCCTGCTAATTCAGATACAGT	0.488000													47	75					0	0	0.139131	0	0
RFC5	5985	broad.mit.edu	37	12	118462710	118462710	+	Nonsense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr12:118462710C>A	uc001twq.2	+	6	601	c.476C>A	c.(475-477)TCA>TAA	p.S159*	RFC5_uc010syx.1_Nonsense_Mutation_p.S138*|RFC5_uc010syy.1_Nonsense_Mutation_p.S138*|RFC5_uc010syz.1_Nonsense_Mutation_p.S74*|RFC5_uc009zwr.2_Nonsense_Mutation_p.S159*	NM_007370	NP_031396	P40937	RFC5_HUMAN	replication factor C 5 isoform 1	159					cell cycle checkpoint|DNA strand elongation involved in DNA replication|nucleotide-excision repair, DNA gap filling|S phase of mitotic cell cycle|telomere maintenance via recombination|telomere maintenance via semi-conservative replication|transcription-coupled nucleotide-excision repair	DNA replication factor C complex|nucleoplasm	ATP binding|DNA clamp loader activity|enzyme binding				0	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)					AACTATCTGTCAAAGATCATC	0.458000													4	52					0.00909568	0.00953722	0.009096	1	0
DCAF4	26094	broad.mit.edu	37	14	73412735	73412735	+	Silent	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr14:73412735G>A	uc001xng.2	+	7	898	c.678G>A	c.(676-678)AAG>AAA	p.K226K	DCAF4_uc001xnj.2_Silent_p.K226K|DCAF4_uc010ttr.1_Silent_p.K204K|DCAF4_uc001xnh.2_Silent_p.K126K|DCAF4_uc010tts.1_Silent_p.K165K|DCAF4_uc010ttt.1_Silent_p.K11K|DCAF4_uc001xni.2_Silent_p.K165K|DCAF4_uc001xnk.2_Silent_p.K226K	NM_015604	NP_056419	Q8WV16	DCAF4_HUMAN	DDB1 and CUL4 associated factor 4 isoform 1	226						CUL4 RING ubiquitin ligase complex				ovary(1)|central_nervous_system(1)|skin(1)	3						CCAACCGGAAGGTACGTTGCC	0.527000													45	76					0	0	0.139131	0	0
RYR3	6263	broad.mit.edu	37	15	33962623	33962623	+	Missense_Mutation	SNP	T	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr15:33962623T>G	uc001zhi.2	+	38	5796	c.5726T>G	c.(5725-5727)GTT>GGT	p.V1909G	RYR3_uc010bar.2_Missense_Mutation_p.V1909G	NM_001036	NP_001027	Q15413	RYR3_HUMAN	ryanodine receptor 3	1909	4 X approximate repeats.|Cytoplasmic (By similarity).				cellular calcium ion homeostasis	integral to membrane	calcium ion binding|receptor activity|ryanodine-sensitive calcium-release channel activity			ovary(5)|central_nervous_system(4)|lung(1)	10		all_lung(180;7.18e-09)		all cancers(64;8.95e-12)|GBM - Glioblastoma multiforme(186;0.00109)|BRCA - Breast invasive adenocarcinoma(123;0.0363)		TTGCTAGGGGTTCCTTTggaa	0.398000													7	17					0	0	0.146539	0	0
RNF111	54778	broad.mit.edu	37	15	59373369	59373369	+	Missense_Mutation	SNP	A	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr15:59373369A>C	uc002afv.2	+	8	2462	c.2183A>C	c.(2182-2184)CAC>CCC	p.H728P	RNF111_uc002afs.2_Missense_Mutation_p.H728P|RNF111_uc002aft.2_Missense_Mutation_p.H728P|RNF111_uc002afu.2_Missense_Mutation_p.H727P|RNF111_uc002afw.2_Missense_Mutation_p.H728P|RNF111_uc002afx.2_Missense_Mutation_p.H254P	NM_017610	NP_060080	Q6ZNA4	RN111_HUMAN	ring finger protein 111	728	Pro-rich.				multicellular organismal development|positive regulation of transcription, DNA-dependent	cytoplasm|nucleus	protein binding|ubiquitin-protein ligase activity|zinc ion binding			ovary(2)	2				all cancers(107;0.194)		CCTCCTACACACCAGCCAATT	0.512000													9	89					0	0	0.146539	0	0
RRN3	54700	broad.mit.edu	37	16	15168670	15168670	+	Missense_Mutation	SNP	G	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:15168670G>T	uc002dde.2	-	11	975	c.907C>A	c.(907-909)CTC>ATC	p.L303I	PDXDC1_uc002ddc.2_Intron|RRN3_uc010uzp.1_Missense_Mutation_p.L171I|RRN3_uc010uzq.1_Missense_Mutation_p.L273I	NM_018427	NP_060897	Q9NYV6	RRN3_HUMAN	RRN3 RNA polymerase I transcription factor	303					regulation of transcription, DNA-dependent|transcription initiation from RNA polymerase I promoter	nucleolus|nucleoplasm				ovary(1)	1						ATCTGGTCGAGCCGTTCAGGA	0.403000													8	65					1.33987e-11	1.53943e-11	0.069234	1	0
GDE1	51573	broad.mit.edu	37	16	19516303	19516303	+	Missense_Mutation	SNP	A	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:19516303A>C	uc002dgh.2	-	5	912	c.748T>G	c.(748-750)TTT>GTT	p.F250V	GDE1_uc002dgi.2_Missense_Mutation_p.F140V	NM_016641	NP_057725	Q9NZC3	GDE1_HUMAN	glycerophosphodiester phosphodiesterase 1	250	Helical; (Potential).|GDPD.				glycerol metabolic process|lipid metabolic process	cytoplasm|integral to membrane	glycerophosphodiester phosphodiesterase activity|glycerophosphoinositol glycerophosphodiesterase activity|metal ion binding			ovary(2)|central_nervous_system(1)	3						ATCATAACAAATATAAAATGT	0.403000													44	105					0	0	0.131918	0	0
EEF2K	29904	broad.mit.edu	37	16	22237117	22237117	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:22237117C>T	uc002dki.2	+	2	552	c.67C>T	c.(67-69)CAT>TAT	p.H23Y	EEF2K_uc002dkh.2_RNA	NM_013302	NP_037434	O00418	EF2K_HUMAN	elongation factor-2 kinase	23					insulin receptor signaling pathway|translational elongation	cytosol	ATP binding|calcium ion binding|calmodulin binding|elongation factor-2 kinase activity|translation factor activity, nucleic acid binding			large_intestine(1)	1				GBM - Glioblastoma multiforme(48;0.0223)		CCGAGCTGGCCATGATGGTGA	0.557000													17	61					0	0	0.033300	0	0
CX3CL1	6376	broad.mit.edu	37	16	57413588	57413588	+	Missense_Mutation	SNP	A	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:57413588A>G	uc002eli.2	+	2	180	c.113A>G	c.(112-114)AAG>AGG	p.K38R		NM_002996	NP_002987	P78423	X3CL1_HUMAN	chemokine (C-X3-C motif) ligand 1 precursor	38	Extracellular (Potential).|Chemokine.				cell adhesion|cytokine-mediated signaling pathway|defense response|immune response|leukocyte adhesive activation|positive regulation of calcium-independent cell-cell adhesion|positive regulation of inflammatory response	cell surface|extracellular space|integral to membrane|plasma membrane	chemokine activity				0						ACGTGCAGCAAGATGACATCA	0.522000													15	61					0	0	0.146539	0	0
SLC12A4	6560	broad.mit.edu	37	16	67981315	67981315	+	Missense_Mutation	SNP	C	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:67981315C>G	uc002euz.2	-	16	2132	c.1991G>C	c.(1990-1992)GGG>GCG	p.G664A	SLC12A4_uc010ceu.2_Missense_Mutation_p.G658A|SLC12A4_uc010vkh.1_Missense_Mutation_p.G633A|SLC12A4_uc010vki.1_Missense_Mutation_p.G664A|SLC12A4_uc010vkj.1_Missense_Mutation_p.G666A|SLC12A4_uc002eva.2_Missense_Mutation_p.G664A|SLC12A4_uc010cev.1_RNA|SLC12A4_uc002evb.2_RNA	NM_005072	NP_005063	Q9UP95	S12A4_HUMAN	solute carrier family 12, member 4 isoform a	664					cell volume homeostasis|potassium ion transport|sodium ion transport	integral to plasma membrane|membrane fraction	potassium:chloride symporter activity			ovary(1)	1		Ovarian(137;0.192)		OV - Ovarian serous cystadenocarcinoma(108;0.0042)|Epithelial(162;0.0185)|all cancers(182;0.121)	Bumetanide(DB00887)|Potassium Chloride(DB00761)	GCCTCGGATCCCGTCACCCCA	0.672000													7	21					0	0	0.029380	0	0
NFATC3	4775	broad.mit.edu	37	16	68224719	68224719	+	Missense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:68224719C>A	uc002evo.1	+	9	2357	c.2147C>A	c.(2146-2148)CCA>CAA	p.P716Q	NFATC3_uc010vkl.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkm.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkn.1_Missense_Mutation_p.P237Q|NFATC3_uc010vko.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkp.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkq.1_Missense_Mutation_p.P237Q|NFATC3_uc002evl.2_Missense_Mutation_p.P237Q|NFATC3_uc002evk.2_Missense_Mutation_p.P716Q|NFATC3_uc002evm.1_Missense_Mutation_p.P716Q|NFATC3_uc002evn.1_Missense_Mutation_p.P716Q|NFATC3_uc010vkr.1_Missense_Mutation_p.P237Q|NFATC3_uc010vks.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkt.1_Missense_Mutation_p.P237Q|NFATC3_uc010vku.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkv.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkw.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkx.1_Missense_Mutation_p.P237Q|NFATC3_uc010vky.1_Missense_Mutation_p.P237Q|NFATC3_uc010vkz.1_Missense_Mutation_p.P237Q|NFATC3_uc010vla.1_Missense_Mutation_p.P237Q|NFATC3_uc010vlb.1_Missense_Mutation_p.P237Q|NFATC3_uc010vlc.1_Missense_Mutation_p.P237Q	NM_173165	NP_775188	Q12968	NFAC3_HUMAN	nuclear factor of activated T-cells,	716					inflammatory response|transcription from RNA polymerase II promoter	nucleolus|plasma membrane	DNA binding			upper_aerodigestive_tract(1)|central_nervous_system(1)|pancreas(1)	3		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.0119)|Epithelial(162;0.0452)|all cancers(182;0.24)		TCTTCAGTTCCATCTTTGCCT	0.383000													78	60					2.09793e-52	2.69734e-52	0.139131	1	0
CHMP1A	5119	broad.mit.edu	37	16	89715819	89715819	+	Silent	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:89715819C>T	uc002fnu.2	-	4	325	c.192G>A	c.(190-192)CGG>CGA	p.R64R	CHMP1A_uc002fnt.2_5'Flank|CHMP1A_uc002fnv.2_Missense_Mutation_p.D58N	NM_002768	NP_002759	Q9HD42	CHM1A_HUMAN	chromatin modifying protein 1A isoform 2	64					cell division|gene silencing|mitotic chromosome condensation|negative regulation of S phase of mitotic cell cycle|negative regulation of transcription by glucose|protein transport|transcription, DNA-dependent|vesicle-mediated transport	condensed nuclear chromosome|early endosome|endomembrane system|endosome membrane|microtubule organizing center|nuclear matrix	metallopeptidase activity|protein domain specific binding|zinc ion binding				0		all_lung(18;3.07e-05)|all_hematologic(23;0.0256)		BRCA - Breast invasive adenocarcinoma(80;0.048)		GGGACGCCATCCGAAGCCAGT	0.602000													53	123					0	0	0.139131	0	0
CDK10	8558	broad.mit.edu	37	16	89756963	89756963	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr16:89756963C>T	uc010cio.2	+	3	206	c.163C>T	c.(163-165)CGG>TGG	p.R55W	CDK10_uc002foa.2_Missense_Mutation_p.R49W|CDK10_uc010cip.2_5'UTR|CDK10_uc010vpl.1_Missense_Mutation_p.R49W|CDK10_uc002fob.2_5'UTR|CDK10_uc002fod.2_5'UTR|CDK10_uc002foe.2_5'UTR|CDK10_uc002fof.2_5'UTR|CDK10_uc002fog.3_5'UTR|CDK10_uc002foh.3_5'UTR	NM_052988	NP_443714	Q15131	CDK10_HUMAN	cyclin-dependent kinase 10 isoform a	55	Protein kinase.				negative regulation of cell proliferation|traversing start control point of mitotic cell cycle		ATP binding|cyclin-dependent protein kinase activity|protein binding			ovary(1)	1		Lung NSC(15;2.19e-05)|all_lung(18;3.07e-05)|all_hematologic(23;0.0256)		BRCA - Breast invasive adenocarcinoma(80;0.0276)		CATTCCAGATCGGGCCCGGGA	0.592000													24	100					0	0	0.083992	0	0
ACAP1	9744	broad.mit.edu	37	17	7250507	7250507	+	Nonsense_Mutation	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:7250507G>A	uc002ggd.2	+	14	1495	c.1289G>A	c.(1288-1290)TGG>TAG	p.W430*		NM_014716	NP_055531	Q15027	ACAP1_HUMAN	centaurin beta1	430	Arf-GAP.|C4-type.|Required for interaction with GULP1.				intracellular signal transduction|lipid metabolic process|protein transport|regulation of ARF GTPase activity		ARF GTPase activator activity|phospholipase C activity|protein binding|zinc ion binding			breast(2)|large_intestine(1)	3						GCCCCGGAGTGGGCCAGCATC	0.657000													31	63					0	0	0.064281	0	0
ATAD5	79915	broad.mit.edu	37	17	29162059	29162059	+	Missense_Mutation	SNP	G	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:29162059G>C	uc002hfs.1	+	2	1306	c.960G>C	c.(958-960)AAG>AAC	p.K320N	ATAD5_uc002hft.1_Missense_Mutation_p.K217N	NM_024857	NP_079133	Q96QE3	ATAD5_HUMAN	ATPase family, AAA domain containing 5	320					response to DNA damage stimulus	nucleus	ATP binding|nucleoside-triphosphatase activity			ovary(3)	3		all_hematologic(16;0.0202)|Acute lymphoblastic leukemia(14;0.0238)|Myeloproliferative disorder(56;0.0393)				TACGCTTTAAGACAGTTACTG	0.378000													22	33					0	0	0.055883	0	0
LRRC37B	114659	broad.mit.edu	37	17	30348539	30348539	+	Missense_Mutation	SNP	G	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:30348539G>T	uc002hgu.2	+	1	385	c.374G>T	c.(373-375)CGG>CTG	p.R125L	LRRC37B_uc010wbx.1_Missense_Mutation_p.R43L|LRRC37B_uc010csu.2_Missense_Mutation_p.R125L	NM_052888	NP_443120	Q96QE4	LR37B_HUMAN	leucine rich repeat containing 37B precursor	125	Extracellular (Potential).					integral to membrane				upper_aerodigestive_tract(1)|ovary(1)	2		Myeloproliferative disorder(56;0.0255)|all_hematologic(16;0.111)|Ovarian(249;0.182)|Breast(31;0.244)				AATGACAAGCGGACTCCAGAA	0.537000													46	95					3.54561e-26	4.40144e-26	0.111260	1	0
KRTAP4-9	100132386	broad.mit.edu	37	17	39262083	39262083	+	Missense_Mutation	SNP	A	C	C	rs75392608		TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:39262083A>C	uc010wfp.1	+	1	443	c.443A>C	c.(442-444)AAC>ACC	p.N148T		NM_001146041	NP_001139513	Q9BYQ8	KRA49_HUMAN	keratin associated protein 4-9	148	29 X 5 AA repeats of C-C-[RQVHIEK]- [SPTR]-[VSTQCRNP].|24.					keratin filament					0						tgccagcccaactgctgccgc	0.100000													3	31					0	0	0.069234	0	0
KRTAP4-9	100132386	broad.mit.edu	37	17	39262103	39262103	+	Missense_Mutation	SNP	A	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:39262103A>T	uc010wfp.1	+	1	463	c.463A>T	c.(463-465)AGC>TGC	p.S155C		NM_001146041	NP_001139513	Q9BYQ8	KRA49_HUMAN	keratin associated protein 4-9	155	29 X 5 AA repeats of C-C-[RQVHIEK]- [SPTR]-[VSTQCRNP].					keratin filament					0						ccccagctgcagcatctccag	0.124000													3	23					0	0	0.058154	0	0
ABI3	51225	broad.mit.edu	37	17	47299547	47299547	+	Silent	SNP	T	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:47299547T>C	uc002iop.1	+	7	1395	c.897T>C	c.(895-897)CCT>CCC	p.P299P	ABI3_uc002ioq.1_Silent_p.P293P	NM_016428	NP_057512	Q9P2A4	ABI3_HUMAN	NESH protein isoform 1	299	Pro-rich.				cellular component movement|regulation of cell migration	cytoplasm|lamellipodium	protein binding				0			Epithelial(5;6.37e-06)|all cancers(6;6.36e-05)			GATTTGGGCCTGATGAGCCCA	0.622000										HNSCC(55;0.14)			4	156					0	0	0.009096	0	0
MFSD11	79157	broad.mit.edu	37	17	74772621	74772621	+	Nonsense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:74772621C>T	uc002jta.2	+	13	2156	c.1183C>T	c.(1183-1185)CAG>TAG	p.Q395*	MFSD11_uc002jtb.2_Nonsense_Mutation_p.Q395*|MFSD11_uc010dha.2_Nonsense_Mutation_p.Q343*|MFSD11_uc002jtc.2_Nonsense_Mutation_p.Q395*|MFSD11_uc002jtd.3_Nonsense_Mutation_p.Q395*|MFSD11_uc010dhb.2_Nonsense_Mutation_p.Q343*|MFSD11_uc002jte.2_Nonsense_Mutation_p.Q395*	NM_024311	NP_077287	O43934	MFS11_HUMAN	major facilitator superfamily domain containing	395	Helical; (Potential).					integral to membrane				ovary(1)	1						CAAGTTTGTTCAGGTAACCTC	0.398000													92	97					0	0	0.139131	0	0
SYT4	6860	broad.mit.edu	37	18	40853823	40853823	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr18:40853823C>T	uc002law.2	-	2	940	c.571G>A	c.(571-573)GAC>AAC	p.D191N	SYT4_uc010dng.2_Intron|SYT4_uc010xcm.1_Missense_Mutation_p.D173N|SYT4_uc010dnh.2_Intron	NM_020783	NP_065834	Q9H2B2	SYT4_HUMAN	synaptotagmin IV	191	Phospholipid binding (Probable).|C2 1.|Cytoplasmic (Potential).	Calcium 1 (By similarity).				cell junction|integral to membrane|synaptic vesicle membrane	transporter activity			skin(5)	5						ATATATGGGTCAGAGGTCATC	0.438000													38	55					0	0	0.104719	0	0
MRPL54	116541	broad.mit.edu	37	19	3765208	3765208	+	Missense_Mutation	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr19:3765208G>A	uc002lyq.3	+	2	197	c.163G>A	c.(163-165)GCC>ACC	p.A55T		NM_172251	NP_758455	Q6P161	RM54_HUMAN	mitochondrial ribosomal protein L54 precursor	55						mitochondrion|ribosome					0		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.00467)|STAD - Stomach adenocarcinoma(1328;0.18)		GACCAGCGAGGCCCTCAAGGA	0.572000													21	21					0	0	0.069288	0	0
Unknown	0	broad.mit.edu	37	19	15890704	15890704	+	RNA	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr19:15890704C>A	uc002nbo.2	-	1		c.94G>T								Homo sapiens cDNA FLJ60024 complete cds, highly similar to Cytochrome P450 4F12 (EC 1.14.14.1).																		CCAGCCAGGACAGGCTCAGCT	0.672000													4	12					1.024e-07	1.12849e-07	0.014758	1	0
ANKLE1	126549	broad.mit.edu	37	19	17396342	17396342	+	Silent	SNP	C	T	T	rs111432888		TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr19:17396342C>T	uc002nga.2	+	7	1755	c.1479C>T	c.(1477-1479)GCC>GCT	p.A493A	ANKLE1_uc010xpm.1_RNA|ANKLE1_uc010eao.1_Silent_p.A489A|ANKLE1_uc010xpn.1_Silent_p.A521A|ANKLE1_uc002nfy.2_Silent_p.A456A|ANKLE1_uc002nfz.2_Silent_p.A199A	NM_152363	NP_689576	Q8NAG6	ANKL1_HUMAN	ankyrin repeat domain 41	493						nuclear envelope					0						GGACGAGGGCCCGGCCATATG	0.617000													48	102					0	0	0.124865	0	0
ZFP14	57677	broad.mit.edu	37	19	36831787	36831787	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr19:36831787C>T	uc002odx.1	-	4	1034	c.941G>A	c.(940-942)TGT>TAT	p.C314Y	ZFP14_uc010xtd.1_Missense_Mutation_p.C315Y|ZFP14_uc010eex.1_Missense_Mutation_p.C314Y	NM_020917	NP_065968	Q9HCL3	ZFP14_HUMAN	zinc finger protein 14-like	314	C2H2-type 6.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)	1	Esophageal squamous(110;0.162)					ACATTCCTTACATTCATAGAG	0.418000													34	53					0	0	0.045705	0	0
ZNF225	7768	broad.mit.edu	37	19	44635911	44635911	+	Silent	SNP	A	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr19:44635911A>C	uc002oyj.1	+	5	1387	c.1144A>C	c.(1144-1146)AGA>CGA	p.R382R	ZNF225_uc010eje.1_Silent_p.R299R|ZNF225_uc010ejf.1_Silent_p.R382R	NM_013362	NP_037494	Q9UK10	ZN225_HUMAN	zinc finger protein 225	382	C2H2-type 8.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Prostate(69;0.0352)|all_neural(266;0.202)				AAAGAGCTTCAGATGGGCCTC	0.408000													41	50					0	0	0.092188	0	0
ZNF547	284306	broad.mit.edu	37	19	57888699	57888699	+	Missense_Mutation	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr19:57888699G>A	uc002qol.2	+	4	548	c.355G>A	c.(355-357)GCA>ACA	p.A119T	ZNF547_uc002qpm.3_Missense_Mutation_p.A45T|ZNF547_uc010ygx.1_Missense_Mutation_p.A119T	NM_173631	NP_775902	Q8IVP9	ZN547_HUMAN	zinc finger protein 547	119					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)|central_nervous_system(1)	2		Colorectal(82;5.46e-05)|all_neural(62;0.0218)|Ovarian(87;0.0694)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.026)		CACGTGTCCAGCACATCTTCA	0.517000													23	57					0	0	0.083992	0	0
ADAM17	6868	broad.mit.edu	37	2	9630624	9630624	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr2:9630624C>T	uc002qzu.2	-	19	2340	c.2157G>A	c.(2155-2157)ATG>ATA	p.M719I	IAH1_uc010yiz.1_Intron|ADAM17_uc010ewy.2_Missense_Mutation_p.M702I|ADAM17_uc010ewz.2_Missense_Mutation_p.M62I	NM_003183	NP_003174	P78536	ADA17_HUMAN	a disintegrin and metalloprotease domain 17	719	Cytoplasmic (Potential).				B cell differentiation|cell adhesion mediated by integrin|epidermal growth factor receptor signaling pathway|epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway|germinal center formation|membrane protein intracellular domain proteolysis|negative regulation of interleukin-8 production|nerve growth factor receptor signaling pathway|Notch signaling pathway|PMA-inducible membrane protein ectodomain proteolysis|positive regulation of cell growth|positive regulation of cell proliferation|positive regulation of chemokine production|positive regulation of cyclin-dependent protein kinase activity involved in G1/S|positive regulation of protein phosphorylation|positive regulation of T cell chemotaxis|positive regulation of transforming growth factor beta receptor signaling pathway|regulation of mast cell apoptosis|response to drug|response to high density lipoprotein particle stimulus|response to hypoxia|response to lipopolysaccharide|spleen development|T cell differentiation in thymus|wound healing, spreading of epidermal cells	actin cytoskeleton|apical plasma membrane|cell surface|cytoplasm|integral to plasma membrane|membrane raft	integrin binding|interleukin-6 receptor binding|metalloendopeptidase activity|PDZ domain binding|SH3 domain binding|zinc ion binding			lung(1)|kidney(1)	2	all_hematologic(175;0.127)|Acute lymphoblastic leukemia(172;0.155)			Epithelial(75;0.225)		ATGCAGAATCCATGCTGCTCA	0.537000													10	35					0	0	0.069234	0	0
FAM49A	81553	broad.mit.edu	37	2	16736394	16736394	+	Missense_Mutation	SNP	A	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr2:16736394A>T	uc010exm.1	-	10	999	c.851T>A	c.(850-852)ATA>AAA	p.I284K	FAM49A_uc002rck.1_Missense_Mutation_p.I284K	NM_030797	NP_110424	Q9H0Q0	FA49A_HUMAN	family with sequence similarity 49, member A	284						intracellular					0	Acute lymphoblastic leukemia(172;0.0734)|all_hematologic(175;0.088)		GBM - Glioblastoma multiforme(3;0.00969)			CAAAACTTTTATGCAGCCTTT	0.458000													7	23					0	0	0.029380	0	0
TTC7A	57217	broad.mit.edu	37	2	47300864	47300864	+	Silent	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr2:47300864C>T	uc002rvo.2	+	20	2747	c.2379C>T	c.(2377-2379)GGC>GGT	p.G793G	TTC7A_uc002rvm.2_Silent_p.G759G|TTC7A_uc010fbb.2_Silent_p.G817G|TTC7A_uc010fbc.2_Silent_p.G439G|TTC7A_uc002rvp.2_Silent_p.G674G|C2orf61_uc010fbd.2_Intron|TTC7A_uc002rvq.2_Silent_p.G533G|TTC7A_uc002rvr.2_Silent_p.G242G	NM_020458	NP_065191	Q9ULT0	TTC7A_HUMAN	tetratricopeptide repeat domain 7A	793	TPR 8.						binding			breast(1)|skin(1)	2		all_hematologic(82;0.152)|Acute lymphoblastic leukemia(82;0.18)	Lung(47;0.0792)|LUSC - Lung squamous cell carcinoma(58;0.114)			GTCGGCTGGGCCACAAGAGCT	0.652000													20	32					0	0	0.055883	0	0
IL1R2	7850	broad.mit.edu	37	2	102626224	102626224	+	Missense_Mutation	SNP	G	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr2:102626224G>T	uc002tbm.2	+	3	497	c.268G>T	c.(268-270)GAC>TAC	p.D90Y	IL1R2_uc002tbn.2_Missense_Mutation_p.D90Y|IL1R2_uc002tbo.1_Missense_Mutation_p.D90Y	NM_004633	NP_004624	P27930	IL1R2_HUMAN	interleukin 1 receptor, type II precursor	90	Extracellular (Potential).|Ig-like C2-type 1.				immune response	integral to membrane|plasma membrane	interleukin-1, Type II, blocking receptor activity			ovary(1)|breast(1)	2					Anakinra(DB00026)	GTGGGCCCAGGACGGTGCTCT	0.597000													72	159					5.21738e-30	6.55206e-30	0.139131	1	0
SLC4A10	57282	broad.mit.edu	37	2	162711596	162711597	+	Missense_Mutation	DNP	CT	AG	AG			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr2:162711596_162711597CT>AG	uc002ubx.3	+	5	717_718	c.533_534CT>AG	c.(532-534)ACT>AAG	p.T178K	SLC4A10_uc010fpa.1_Missense_Mutation_p.T190K|SLC4A10_uc010zcr.1_RNA|SLC4A10_uc002uby.3_Missense_Mutation_p.T178K|SLC4A10_uc010zcs.1_Missense_Mutation_p.T189K	NM_022058	NP_071341	Q6U841	S4A10_HUMAN	solute carrier family 4, sodium bicarbonate	178	Cytoplasmic (Potential).				bicarbonate transport|chloride transport|sodium ion transport	integral to membrane|plasma membrane	inorganic anion exchanger activity|symporter activity			ovary(2)|lung(2)|pancreas(1)	5						CTGAATGGAACTGTGTTGCTGG	0.396000													26	40					0	0	0.115264	0	0
CYBRD1	79901	broad.mit.edu	37	2	172379114	172379114	+	Missense_Mutation	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr2:172379114G>A	uc002ugy.3	+	1	249	c.59G>A	c.(58-60)GGC>GAC	p.G20D	CYBRD1_uc002ugz.3_Missense_Mutation_p.G20D	NM_024843	NP_079119	Q53TN4	CYBR1_HUMAN	cytochrome b reductase 1 isoform 1	20	Cytochrome b561.|Helical; Name=1; (Potential).				cellular iron ion homeostasis|electron transport chain|transmembrane transport	integral to membrane	ferric-chelate reductase activity|metal ion binding				0						CTGCTCGTCGGCTTCCTGTCG	0.652000													4	32					0	0	0.009096	0	0
RAPH1	65059	broad.mit.edu	37	2	204305855	204305855	+	Silent	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr2:204305855C>T	uc002vad.2	-	14	2283	c.2058G>A	c.(2056-2058)CCG>CCA	p.P686P		NM_213589	NP_998754	Q70E73	RAPH1_HUMAN	Ras association and pleckstrin homology domains	686					cell-matrix adhesion|signal transduction	cytoplasm|cytoskeleton|filopodium|lamellipodium|nucleus|plasma membrane				ovary(3)|breast(3)|central_nervous_system(2)|lung(1)|skin(1)	10						GGGGTGTTGGCGGCTTAAACA	0.463000													4	74					0	0	0.014758	0	0
NINL	22981	broad.mit.edu	37	20	25457543	25457543	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr20:25457543C>T	uc002wux.1	-	17	2458	c.2384G>A	c.(2383-2385)CGC>CAC	p.R795H	NINL_uc010gdn.1_Intron	NM_025176	NP_079452	Q9Y2I6	NINL_HUMAN	ninein-like	795					G2/M transition of mitotic cell cycle	cytosol|microtubule|microtubule organizing center	calcium ion binding			ovary(2)|pancreas(1)|central_nervous_system(1)|skin(1)	5						CATCTGGGCGCGCTTCTCGCT	0.692000													4	21					0	0	0.009096	0	0
ITGB2	3689	broad.mit.edu	37	21	46306670	46306670	+	Missense_Mutation	SNP	A	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr21:46306670A>C	uc002zgd.2	-	14	2272	c.2228T>G	c.(2227-2229)CTC>CGC	p.L743R	ITGB2_uc002zge.2_Missense_Mutation_p.L743R|ITGB2_uc002zgf.3_Missense_Mutation_p.L743R|ITGB2_uc011afl.1_Missense_Mutation_p.L665R|ITGB2_uc010gpw.2_Missense_Mutation_p.L686R|ITGB2_uc002zgg.2_Missense_Mutation_p.L743R	NM_001127491	NP_001120963	P05107	ITB2_HUMAN	integrin, beta 2 precursor	743	Cytoplasmic (Potential).				apoptosis|blood coagulation|cell-cell signaling|cell-matrix adhesion|inflammatory response|integrin-mediated signaling pathway|leukocyte cell-cell adhesion|multicellular organismal development|neutrophil chemotaxis|regulation of cell shape|regulation of immune response|regulation of peptidyl-tyrosine phosphorylation	integrin complex	glycoprotein binding|protein kinase binding|receptor activity			ovary(4)|central_nervous_system(3)|breast(2)	9				Colorectal(79;0.0669)	Simvastatin(DB00641)	CTGGGACTTGAGCTTCTCCTT	0.617000													6	35					0	0	0.021553	0	0
LOC96610	96610	broad.mit.edu	37	22	22664141	22664141	+	RNA	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr22:22664141G>A	uc011aim.1	+	30		c.1998G>A			LOC96610_uc011aiq.1_RNA					Parts of antibodies, mostly variable regions.												0						AAATTTGAAGGTGCTGTGATT	0.448000													3	32					0	0	0.115264	0	0
NF2	4771	broad.mit.edu	37	22	30038223	30038223	+	Nonsense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr22:30038223C>A	uc003age.3	+	4	839	c.396C>A	c.(394-396)TAC>TAA	p.Y132*	NF2_uc003afy.3_Nonsense_Mutation_p.Y132*|NF2_uc003afz.3_Nonsense_Mutation_p.Y49*|NF2_uc003agf.3_Nonsense_Mutation_p.Y132*|NF2_uc003agb.3_Nonsense_Mutation_p.Y55*|NF2_uc003agc.3_Nonsense_Mutation_p.Y94*|NF2_uc003agd.3_RNA|NF2_uc003agg.3_Nonsense_Mutation_p.Y132*|NF2_uc003aga.3_Nonsense_Mutation_p.Y90*|NF2_uc003agh.3_Nonsense_Mutation_p.Y91*|NF2_uc003agi.3_Nonsense_Mutation_p.Y49*|NF2_uc003agj.3_Nonsense_Mutation_p.Y132*|NF2_uc003agk.3_Nonsense_Mutation_p.Y94*	NM_000268	NP_000259	P35240	MERL_HUMAN	neurofibromin 2 isoform 1	132	FERM.				actin cytoskeleton organization|negative regulation of cell migration|negative regulation of cell proliferation|negative regulation of cell-cell adhesion|negative regulation of cell-matrix adhesion|negative regulation of DNA replication|negative regulation of tyrosine phosphorylation of Stat3 protein|negative regulation of tyrosine phosphorylation of Stat5 protein|positive regulation of stress fiber assembly|regulation of hippo signaling cascade|Schwann cell proliferation	cytoskeleton|early endosome|extrinsic to membrane|filopodium membrane|nucleolus|perinuclear region of cytoplasm|ruffle membrane	cytoskeletal protein binding|protein binding	p.V122_K149del(5)|p.L127_D382del(1)|p.L127_P134del(1)|p.K123fs*2(1)|p.V110_L141del(1)		meninges(372)|soft_tissue(284)|central_nervous_system(20)|kidney(10)|pleura(9)|skin(7)|large_intestine(5)|breast(5)|urinary_tract(3)|thyroid(2)|endometrium(2)|ovary(2)|lung(2)|stomach(2)|bone(2)|pituitary(1)	728						AAAAGATCTACTGCCCTCCTG	0.468000			D|Mis|N|F|S|O		meningioma|acoustic neuroma|renal 	meningioma|acoustic neuroma			Neurofibromatosis_type_2				30	13					1.45844e-13	1.73089e-13	0.054565	1	0
STAC	6769	broad.mit.edu	37	3	36587768	36587768	+	Missense_Mutation	SNP	T	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr3:36587768T>G	uc003cgh.1	+	11	1235	c.1196T>G	c.(1195-1197)CTA>CGA	p.L399R	STAC_uc011aya.1_Missense_Mutation_p.L338R	NM_003149	NP_003140	Q99469	STAC_HUMAN	SH3 and cysteine rich domain	399					intracellular signal transduction	cytoplasm|soluble fraction	metal ion binding			skin(2)|ovary(1)|pancreas(1)	4						CTTGATGTACTAGAAAACATC	0.493000													47	14					0	0	0.139131	0	0
SETD2	29072	broad.mit.edu	37	3	47061276	47061276	+	Nonsense_Mutation	SNP	T	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr3:47061276T>A	uc003cqs.2	-	19	7458	c.7405A>T	c.(7405-7407)AAA>TAA	p.K2469*	SETD2_uc003cqv.2_Nonsense_Mutation_p.K2536*|SETD2_uc003cqr.2_Nonsense_Mutation_p.K68*	NM_014159	NP_054878	Q9BYW2	SETD2_HUMAN	SET domain containing 2	2469	Interaction with POLR2A.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleus	DNA binding|histone-lysine N-methyltransferase activity|oxidoreductase activity|transition metal ion binding			kidney(24)|ovary(5)|skin(1)|central_nervous_system(1)|breast(1)	32		Acute lymphoblastic leukemia(5;0.0169)		BRCA - Breast invasive adenocarcinoma(193;0.000302)|KIRC - Kidney renal clear cell carcinoma(197;0.00732)|Kidney(197;0.00844)		TCTTTGCTTTTCTTTGCTAGT	0.428000			N|F|S|Mis		clear cell renal carcinoma								56	9					0	0	0.139131	0	0
NPRL2	10641	broad.mit.edu	37	3	50386372	50386372	+	Missense_Mutation	SNP	T	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr3:50386372T>A	uc003daj.1	-	5	921	c.518A>T	c.(517-519)GAT>GTT	p.D173V	NPRL2_uc003dai.1_Missense_Mutation_p.D53V|CYB561D2_uc003dak.2_5'Flank|CYB561D2_uc003dal.2_5'Flank|CYB561D2_uc003dam.2_5'Flank	NM_006545	NP_006536	Q8WTW4	NPRL2_HUMAN	tumor suppressor candidate 4	173					negative regulation of kinase activity		protein binding|protein kinase activity			lung(1)	1						GACAGGTACATCATACTCCTG	0.537000													89	33					0	0	0.139131	0	0
BAP1	8314	broad.mit.edu	37	3	52441190	52441190	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr3:52441190C>T	uc003ddx.2	-	7	695	c.580G>A	c.(580-582)GGG>AGG	p.G194R	BAP1_uc010hmh.2_5'Flank	NM_004656	NP_004647	Q92560	BAP1_HUMAN	BRCA1 associated protein-1	194					monoubiquitinated histone H2A deubiquitination|negative regulation of cell proliferation|protein K48-linked deubiquitination|regulation of cell cycle|regulation of cell growth|ubiquitin-dependent protein catabolic process	cytoplasm|nucleolus|PR-DUB complex	chromatin binding|protein binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity	p.?(1)		pleura(32)|eye(28)|lung(2)|ovary(2)|breast(1)	65				BRCA - Breast invasive adenocarcinoma(193;1.72e-05)|Kidney(197;0.0018)|KIRC - Kidney renal clear cell carcinoma(197;0.00203)|OV - Ovarian serous cystadenocarcinoma(275;0.0277)		TGGTGCCTACCATGGTCAATG	0.597000			N|Mis|F|S|O		uveal melanoma|breast|NSCLC								30	13					0	0	0.134883	0	0
ZBTB11	27107	broad.mit.edu	37	3	101378652	101378652	+	Missense_Mutation	SNP	G	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr3:101378652G>C	uc003dve.3	-	6	2251	c.2021C>G	c.(2020-2022)ACA>AGA	p.T674R		NM_014415	NP_055230	O95625	ZBT11_HUMAN	zinc finger protein ZNF-U69274	674					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			skin(1)	1						CTTTACACCTGTGTGCTTTAA	0.373000													31	47					0	0	0.050027	0	0
KCTD8	386617	broad.mit.edu	37	4	44450342	44450342	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr4:44450342C>T	uc003gwu.2	-	1	483	c.199G>A	c.(199-201)GAC>AAC	p.D67N		NM_198353	NP_938167	Q6ZWB6	KCTD8_HUMAN	potassium channel tetramerisation domain	67	BTB.					cell junction|postsynaptic membrane|presynaptic membrane|voltage-gated potassium channel complex	voltage-gated potassium channel activity			central_nervous_system(2)|ovary(1)	3						AAAGTACTGTCCGGGACGCTG	0.522000										HNSCC(17;0.042)			13	18					0	0	0.105934	0	0
PPAT	5471	broad.mit.edu	37	4	57262889	57262889	+	Missense_Mutation	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr4:57262889G>A	uc003hbr.2	-	10	1455	c.1253C>T	c.(1252-1254)GCT>GTT	p.A418V		NM_002703	NP_002694	Q06203	PUR1_HUMAN	phosphoribosyl pyrophosphate amidotransferase	418					glutamine metabolic process|nucleoside metabolic process|purine base biosynthetic process|purine ribonucleoside monophosphate biosynthetic process	cytosol	4 iron, 4 sulfur cluster binding|amidophosphoribosyltransferase activity|metal ion binding				0	Glioma(25;0.08)|all_neural(26;0.101)				L-Glutamine(DB00130)|Thioguanine(DB00352)	TGGTGGTGAAGCTACTCGAAT	0.338000													22	38					0	0	0.083992	0	0
CDC20B	166979	broad.mit.edu	37	5	54429246	54429246	+	Missense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr5:54429246C>A	uc003jpo.1	-	6	866	c.691G>T	c.(691-693)GAC>TAC	p.D231Y	CDC20B_uc003jpn.1_Missense_Mutation_p.D231Y|CDC20B_uc010ivu.1_Missense_Mutation_p.D231Y|CDC20B_uc010ivv.1_Missense_Mutation_p.D231Y	NM_152623	NP_689836	Q86Y33	CD20B_HUMAN	CDC20 cell division cycle 20 homolog B isoform	231	WD 1.										0		Lung NSC(810;0.000744)|Breast(144;0.159)|Prostate(74;0.194)	LUSC - Lung squamous cell carcinoma(15;0.225)			TTACAGTAGTCATTTCGAAGA	0.353000													36	57					3.11337e-16	3.77803e-16	0.054565	1	0
OTP	23440	broad.mit.edu	37	5	76932809	76932809	+	Missense_Mutation	SNP	G	C	C	rs148662448	byFrequency	TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr5:76932809G>C	uc003kfg.2	-	2	432	c.284C>G	c.(283-285)GCC>GGC	p.A95G		NM_032109	NP_115485	Q5XKR4	OTP_HUMAN	orthopedia homeobox	95						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			pancreas(1)	1		all_lung(232;0.00051)|Lung NSC(167;0.000601)|Ovarian(174;0.0105)|Prostate(461;0.214)		OV - Ovarian serous cystadenocarcinoma(54;9.04e-51)|Epithelial(54;1.62e-45)|all cancers(79;4.4e-41)		CTGCTGGCCGGCTTGGCTGGG	0.677000													44	85					0	0	0.124865	0	0
AFF4	27125	broad.mit.edu	37	5	132270292	132270292	+	Silent	SNP	T	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr5:132270292T>G	uc003kyd.2	-	3	873	c.465A>C	c.(463-465)TCA>TCC	p.S155S	AFF4_uc011cxk.1_5'UTR|AFF4_uc003kye.1_Silent_p.S155S|AFF4_uc003kyf.3_Silent_p.S155S	NM_014423	NP_055238	Q9UHB7	AFF4_HUMAN	ALL1 fused gene from 5q31	155	Ser-rich.				transcription from RNA polymerase II promoter	mitochondrion|nucleolus	protein binding|sequence-specific DNA binding transcription factor activity			ovary(2)|kidney(2)|skin(1)	5		all_cancers(142;0.145)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)			TATTGTTATATGACTCACGGT	0.522000													53	75					0	0	0.139131	0	0
CDK13	8621	broad.mit.edu	37	7	40134552	40134552	+	Silent	SNP	A	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr7:40134552A>G	uc003thh.3	+	14	4794	c.4512A>G	c.(4510-4512)AGA>AGG	p.R1504R	CDK13_uc003thi.3_Silent_p.R1444R|CDK13_uc003thj.2_Silent_p.R555R|CDK13_uc003thk.2_Silent_p.R437R	NM_003718	NP_003709	Q14004	CDK13_HUMAN	cell division cycle 2-like 5 isoform 1	1504					alternative nuclear mRNA splicing, via spliceosome|hemopoiesis|interspecies interaction between organisms|phosphorylation of RNA polymerase II C-terminal domain|positive regulation of cell proliferation|regulation of mitosis	nuclear cyclin-dependent protein kinase holoenzyme complex|nuclear speck	ATP binding|cyclin-dependent protein kinase activity|protein binding|RNA polymerase II carboxy-terminal domain kinase activity			lung(2)|skin(2)|ovary(1)	5						CAACTGGCAGAGGCAGAGGCA	0.483000													3	140					0	0	0.115264	0	0
FOXP2	93986	broad.mit.edu	37	7	114299729	114299729	+	Splice_Site	SNP	G	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr7:114299729G>A	uc003vhb.2	+	13	2021	c.1647_splice	c.e13+1	p.K549_splice	FOXP2_uc003vgu.2_Splice_Site|FOXP2_uc003vgz.2_Splice_Site_p.K574_splice|FOXP2_uc003vha.2_Splice_Site_p.K457_splice|FOXP2_uc011kmu.1_Splice_Site_p.K566_splice|FOXP2_uc011kmv.1_Splice_Site_p.K548_splice|FOXP2_uc010ljz.1_Splice_Site_p.K364_splice|FOXP2_uc003vhe.1_Splice_Site_p.K119_splice	NM_014491	NP_055306	O15409	FOXP2_HUMAN	forkhead box P2 isoform I						camera-type eye development|caudate nucleus development|cerebellum development|cerebral cortex development|embryo development|growth|lung alveolus development|negative regulation of transcription, DNA-dependent|pattern specification process|positive regulation of epithelial cell proliferation involved in lung morphogenesis|positive regulation of mesenchymal cell proliferation|post-embryonic development|putamen development|regulation of sequence-specific DNA binding transcription factor activity|righting reflex|skeletal muscle tissue development|smooth muscle tissue development|vocal learning	cytoplasm|transcription factor complex	chromatin binding|DNA bending activity|double-stranded DNA binding|promoter binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|zinc ion binding			ovary(4)|pancreas(1)|lung(1)|breast(1)|skin(1)	8						AACTTGGAAGGTAACTACTTT	0.274000													19	29					0	0	0.049695	0	0
NDUFB2	4708	broad.mit.edu	37	7	140402766	140402766	+	Missense_Mutation	SNP	T	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr7:140402766T>A	uc003vwa.2	+	2	263	c.199T>A	c.(199-201)TTC>ATC	p.F67I	NDUFB2_uc010lnl.2_RNA	NM_004546	NP_004537	O95178	NDUB2_HUMAN	NADH dehydrogenase (ubiquinone) 1 beta	67					mitochondrial electron transport, NADH to ubiquinone|transport	mitochondrial respiratory chain complex I	NADH dehydrogenase (ubiquinone) activity			ovary(1)|central_nervous_system(1)	2	Melanoma(164;0.00956)				NADH(DB00157)	ACTCATGTGGTTCTGGATTCT	0.547000													66	131					0	0	0.139131	0	0
SGK223	157285	broad.mit.edu	37	8	8234118	8234118	+	Missense_Mutation	SNP	C	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr8:8234118C>A	uc003wsh.3	-	2	1801	c.1801G>T	c.(1801-1803)GGT>TGT	p.G601C		NM_001080826	NP_001074295	Q86YV5	SG223_HUMAN	pragmin	601							ATP binding|non-membrane spanning protein tyrosine kinase activity				0						ATAGCGACACCGTTGGTCCGG	0.662000													20	53					3.51602e-12	4.08312e-12	0.049695	1	0
ZNF395	55893	broad.mit.edu	37	8	28209093	28209093	+	Silent	SNP	C	A	A	rs145491469	byFrequency	TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr8:28209093C>A	uc003xgq.2	-	7	1240	c.1152G>T	c.(1150-1152)CCG>CCT	p.P384P	ZNF395_uc003xgt.2_Silent_p.P384P|ZNF395_uc003xgr.2_Silent_p.P384P|ZNF395_uc003xgs.2_Silent_p.P384P	NM_018660	NP_061130	Q9H8N7	ZN395_HUMAN	zinc finger protein 395	384					transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|zinc ion binding				0		Ovarian(32;2.06e-05)		KIRC - Kidney renal clear cell carcinoma(542;0.102)|Kidney(114;0.123)|Colorectal(74;0.142)		GGGAGGACTCCGGGCCAGGAT	0.642000													53	100					6.3008e-33	8.00573e-33	0.139131	1	0
PLEC	5339	broad.mit.edu	37	8	144998457	144998457	+	Silent	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr8:144998457C>T	uc003zaf.1	-	31	6221	c.6051G>A	c.(6049-6051)CTG>CTA	p.L2017L	PLEC_uc003zab.1_Silent_p.L1880L|PLEC_uc003zac.1_Silent_p.L1884L|PLEC_uc003zad.2_Silent_p.L1880L|PLEC_uc003zae.1_Silent_p.L1848L|PLEC_uc003zag.1_Silent_p.L1858L|PLEC_uc003zah.2_Silent_p.L1866L|PLEC_uc003zaj.2_Silent_p.L1907L	NM_201380	NP_958782	Q15149	PLEC_HUMAN	plectin isoform 1	2017	Central fibrous rod domain.|Potential.				cellular component disassembly involved in apoptosis|hemidesmosome assembly	cytosol|focal adhesion|hemidesmosome|intermediate filament cytoskeleton|sarcolemma	actin binding|structural constituent of muscle|structural constituent of muscle			large_intestine(2)|ovary(2)|pancreas(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)|skin(1)	9						CCTGCTCCTCCAGCCGCCGCC	0.706000													6	7					0	0	0.029380	0	0
KIAA1432	57589	broad.mit.edu	37	9	5765734	5765734	+	Missense_Mutation	SNP	G	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr9:5765734G>T	uc003zji.2	+	20	2929	c.2836G>T	c.(2836-2838)GTT>TTT	p.V946F	KIAA1432_uc003zjh.2_Missense_Mutation_p.V946F|KIAA1432_uc003zjl.3_Missense_Mutation_p.V909F|KIAA1432_uc003zjj.1_Missense_Mutation_p.V488F|ERMP1_uc011lme.1_RNA	NM_020829	NP_065880	Q4ADV7	RIC1_HUMAN	connexin 43-interacting protein 150 isoform a	1025						integral to membrane					0		Acute lymphoblastic leukemia(23;0.154)		GBM - Glioblastoma multiforme(50;0.000525)|Lung(218;0.122)		AGCTGAAAATGTTCCTGCCAG	0.408000													11	139					1.58986e-06	1.7344e-06	0.069234	1	0
VPS13A	23230	broad.mit.edu	37	9	79955424	79955424	+	Silent	SNP	T	A	A	rs144477984	byFrequency	TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr9:79955424T>A	uc004akr.2	+	50	7244	c.6984T>A	c.(6982-6984)GCT>GCA	p.A2328A	VPS13A_uc004akp.3_Silent_p.A2328A|VPS13A_uc004akq.3_Silent_p.A2328A|VPS13A_uc004aks.2_Silent_p.A2289A	NM_033305	NP_150648	Q96RL7	VP13A_HUMAN	vacuolar protein sorting 13A isoform A	2328					Golgi to endosome transport|protein transport	intracellular	protein binding			pancreas(3)|skin(3)|ovary(2)|large_intestine(1)|central_nervous_system(1)	10						TATCAGTGGCTGAAGAAGGAA	0.333000													36	42					0	0	0.080422	0	0
Unknown	0	broad.mit.edu	37	9	88431070	88431070	+	RNA	SNP	T	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr9:88431070T>G	uc004aog.1	+	2		c.374T>G			uc004aoh.1_Intron					Homo sapiens cDNA FLJ42532 fis, clone BRACE3003004.																		TTATAACACATGTATAAAGCC	0.403000													7	34					0	0	0.029380	0	0
MUSK	4593	broad.mit.edu	37	9	113530177	113530177	+	Missense_Mutation	SNP	C	G	G			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr9:113530177C>G	uc004bey.2	+	8	1096	c.998C>G	c.(997-999)GCT>GGT	p.A333G		NM_005592	NP_005583	O15146	MUSK_HUMAN	skeletal muscle receptor tyrosine kinase	333	FZ.|Extracellular (Potential).				transmembrane receptor protein tyrosine kinase signaling pathway	integral to plasma membrane	ATP binding|transmembrane receptor protein tyrosine kinase activity			lung(3)|ovary(2)|central_nervous_system(1)	6						GCAAAAGATGCTCTTGTTTTT	0.493000													3	126					0	0	0.115264	0	0
SLC9A7	84679	broad.mit.edu	37	X	46491075	46491075	+	Silent	SNP	A	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chrX:46491075A>T	uc004dgu.1	-	14	1691	c.1683T>A	c.(1681-1683)GTT>GTA	p.V561V		NM_032591	NP_115980	Q96T83	SL9A7_HUMAN	solute carrier family 9, member 7	561					regulation of pH	Golgi membrane|integral to membrane|recycling endosome membrane|trans-Golgi network	potassium:hydrogen antiporter activity|protein homodimerization activity|sodium:hydrogen antiporter activity			ovary(2)	2						GATCGGGGTCAACACCAACTC	0.478000													15	27					0	0	0.146539	0	0
HUWE1	10075	broad.mit.edu	37	X	53564649	53564649	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chrX:53564649C>T	uc004dsp.2	-	78	12407	c.12005G>A	c.(12004-12006)CGC>CAC	p.R4002H	HUWE1_uc004dsn.2_Missense_Mutation_p.R2810H|HUWE1_uc004dsq.1_Missense_Mutation_p.R302H	NM_031407	NP_113584	Q7Z6Z7	HUWE1_HUMAN	HECT, UBA and WWE domain containing 1	4002					base-excision repair|cell differentiation|histone ubiquitination|protein monoubiquitination|protein polyubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process	cytoplasm|nucleus	DNA binding|protein binding|ubiquitin-protein ligase activity			ovary(8)|large_intestine(4)|breast(4)|kidney(1)	17						CAGCTCTTGGCGGAAATATCT	0.473000													3	30					0	0	0.115264	0	0
NXF3	56000	broad.mit.edu	37	X	102332664	102332664	+	Missense_Mutation	SNP	C	T	T			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chrX:102332664C>T	uc004eju.2	-	18	1533	c.1462G>A	c.(1462-1464)GTG>ATG	p.V488M	NXF3_uc010noi.1_Missense_Mutation_p.R334H	NM_022052	NP_071335	Q9H4D5	NXF3_HUMAN	nuclear RNA export factor 3	488	NTF2.					cytoplasm|nuclear RNA export factor complex	nucleocytoplasmic transporter activity|nucleotide binding|protein binding			ovary(1)|lung(1)|central_nervous_system(1)	3						TTGTCATTCACGATGCACAGA	0.557000													5	121					0	0	0.014758	0	0
MAGEA12	4111	broad.mit.edu	37	X	151896244	151896244	+	RNA	SNP	A	C	C			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chrX:151896244A>C	uc004fgb.2	-	4		c.523T>G						P43365	MAGAC_HUMAN	Homo sapiens melanoma antigen family A, 12, mRNA (cDNA clone MGC:4914 IMAGE:3450217), complete cds.											skin(1)	1	Acute lymphoblastic leukemia(192;6.56e-05)					GTGTTGGCCCACTCCATTCCT	0.522000													13	64					0	0	0.132662	0	0
RERE	473	broad.mit.edu	37	1	8425998	8425998	+	Frame_Shift_Del	DEL	T	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:8425998delT	uc001ape.2	-	14	2131	c.1321delA	c.(1321-1323)ACCfs	p.T441fs	RERE_uc001apf.2_Frame_Shift_Del_p.T441fs|RERE_uc010nzx.1_Frame_Shift_Del_p.T173fs|RERE_uc001apd.2_5'UTR	NM_012102	NP_036234	Q9P2R6	RERE_HUMAN	atrophin-1 like protein isoform a	441	SANT.				multicellular organismal development|NLS-bearing substrate import into nucleus	mitochondrion	poly-glutamine tract binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(1)|central_nervous_system(1)	2	Ovarian(185;0.0661)	all_epithelial(116;1.17e-21)|all_lung(118;1.4e-06)|Lung NSC(185;3.06e-06)|Renal(390;0.000147)|Breast(348;0.000206)|Colorectal(325;0.00187)|Hepatocellular(190;0.00825)|Ovarian(437;0.0253)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|all cancers(8;9.64e-67)|GBM - Glioblastoma multiforme(8;9.89e-33)|Colorectal(212;1.45e-07)|COAD - Colon adenocarcinoma(227;3.42e-05)|Kidney(185;6e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000533)|KIRC - Kidney renal clear cell carcinoma(229;0.00106)|STAD - Stomach adenocarcinoma(132;0.00118)|READ - Rectum adenocarcinoma(331;0.0419)|Lung(427;0.195)		GCTTCGGGGGTCTTCTTCCAA	0.622													9	29	---	---	---	---					
DNAJC16	23341	broad.mit.edu	37	1	15894493	15894493	+	Frame_Shift_Del	DEL	G	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr1:15894493delG	uc001aws.2	+	15	2290	c.2170delG	c.(2170-2172)GGGfs	p.G724fs	DNAJC16_uc001awt.2_Frame_Shift_Del_p.G412fs|DNAJC16_uc001awu.2_RNA	NM_015291	NP_056106	Q9Y2G8	DJC16_HUMAN	DnaJ (Hsp40) homolog, subfamily C, member 16	724	Extracellular (Potential).				cell redox homeostasis|protein folding	integral to membrane	heat shock protein binding|unfolded protein binding			urinary_tract(1)|lung(1)|kidney(1)	3		Colorectal(325;0.00108)|Renal(390;0.00145)|Breast(348;0.00173)|all_lung(284;0.00459)|Lung NSC(340;0.00499)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0798)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;9.18e-07)|COAD - Colon adenocarcinoma(227;4.5e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000133)|KIRC - Kidney renal clear cell carcinoma(229;0.00262)|STAD - Stomach adenocarcinoma(313;0.00774)|READ - Rectum adenocarcinoma(331;0.0657)		GGAAGCCATAGGGTCGTGCAG	0.512													17	59	---	---	---	---					
OR51A4	401666	broad.mit.edu	37	11	4967850	4967856	+	Frame_Shift_Del	DEL	AGGGAAG	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr11:4967850_4967856delAGGGAAG	uc010qys.1	-	1	475_481	c.475_481delCTTCCCT	c.(475-483)CTTCCCTTCfs	p.L159fs		NM_001005329	NP_001005329	Q8NGJ6	O51A4_HUMAN	olfactory receptor, family 51, subfamily A,	159_161	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)|skin(1)	3		Medulloblastoma(188;0.0075)|all_neural(188;0.0577)|Breast(177;0.086)		Epithelial(150;3.22e-11)|BRCA - Breast invasive adenocarcinoma(625;0.0284)|LUSC - Lung squamous cell carcinoma(625;0.19)		GTGAAAGGGAAGGGAAGAACCAGGAGC	0.440													46	296	---	---	---	---					
OR51A2	401667	broad.mit.edu	37	11	4976463	4976469	+	Frame_Shift_Del	DEL	AGGGAAG	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr11:4976463_4976469delAGGGAAG	uc010qyt.1	-	1	475_481	c.475_481delCTTCCCT	c.(475-483)CTTCCCTTCfs	p.L159fs		NM_001004748	NP_001004748	Q8NGJ7	O51A2_HUMAN	olfactory receptor, family 51, subfamily A,	159_161	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity				0		Medulloblastoma(188;0.0075)|all_neural(188;0.0577)|Breast(177;0.086)		Epithelial(150;3.22e-11)|BRCA - Breast invasive adenocarcinoma(625;0.0284)|LUSC - Lung squamous cell carcinoma(625;0.19)		GTGAAAGGGAAGGGAAGAACCAGGAGC	0.440													27	114	---	---	---	---					
FLJ40504	284085	broad.mit.edu	37	17	26604362	26604363	+	Frame_Shift_Ins	INS	-	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr17:26604362_26604363insA	uc002has.3	-	3	208_209	c.112_113insT	c.(112-114)CATfs	p.H38fs		NM_173624	NP_775895			SubName: Full=Putative uncharacterized protein FLJ40504; SubName: Full=cDNA FLJ40504 fis, clone TESTI2045509, highly similar to KERATIN, TYPE I CYTOSKELETAL 18;												0	all_lung(13;0.000238)|Lung NSC(42;0.000789)			UCEC - Uterine corpus endometrioid carcinoma (53;0.155)		GTGAAGTTCATGCTGTCCGGGG	0.510													35	41	---	---	---	---					
ZNF30	90075	broad.mit.edu	37	19	35434608	35434608	+	Frame_Shift_Del	DEL	G	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr19:35434608delG	uc010edp.1	+	5	1116	c.738delG	c.(736-738)AAGfs	p.K246fs	ZNF30_uc002nxf.2_Frame_Shift_Del_p.K165fs|ZNF30_uc010edq.1_Frame_Shift_Del_p.K247fs|ZNF30_uc010edr.1_Frame_Shift_Del_p.K247fs	NM_194325	NP_919306	P17039	ZNF30_HUMAN	zinc finger protein 30 isoform b	246	C2H2-type 5.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)|central_nervous_system(1)	2	all_lung(56;8.38e-08)|Lung NSC(56;1.31e-07)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0849)	GBM - Glioblastoma multiforme(1328;0.0265)		TATATGGAAAGCTTACCCGGC	0.443													8	13	---	---	---	---					
TMEM144	55314	broad.mit.edu	37	4	159138552	159138552	+	Frame_Shift_Del	DEL	A	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr4:159138552delA	uc003ipx.2	+	5	832	c.312delA	c.(310-312)TTAfs	p.L104fs	TMEM144_uc010iqi.2_RNA	NM_018342	NP_060812	Q7Z5S9	TM144_HUMAN	transmembrane protein 144	104	Helical; (Potential).					integral to membrane					0	all_hematologic(180;0.24)	Renal(120;0.0854)		COAD - Colon adenocarcinoma(41;0.0539)		TTAATGCCTTAACTGGCTGGG	0.274													26	37	---	---	---	---					
SEPT7	989	broad.mit.edu	37	7	35930341	35930341	+	Frame_Shift_Del	DEL	A	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr7:35930341delA	uc010kxc.2	+	10	1129	c.936delA	c.(934-936)AGAfs	p.R312fs	SEPT7_uc011kat.1_Frame_Shift_Del_p.R311fs|SEPT7_uc011kau.1_Frame_Shift_Del_p.R276fs|SEPT7_uc011kav.1_Frame_Shift_Del_p.R259fs|SEPT7_uc003tey.2_Frame_Shift_Del_p.R160fs	NM_001788	NP_001779	Q16181	SEPT7_HUMAN	cell division cycle 10 isoform 1	312					cilium morphogenesis|cytokinesis|mitosis|protein heterooligomerization|regulation of embryonic cell shape	cilium axoneme|cleavage furrow|condensed chromosome kinetochore|midbody|nucleus|septin complex|spindle|stress fiber	GTP binding|protein binding|structural molecule activity				0						ACAGAAGCAGAAAACTTGCAG	0.333													15	16	---	---	---	---					
PODXL	5420	broad.mit.edu	37	7	131241030	131241035	+	In_Frame_Del	DEL	GGCGAC	-	-	rs11277659		TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr7:131241030_131241035delGGCGAC	uc003vqw.3	-	1	342_347	c.84_89delGTCGCC	c.(82-90)CCGTCGCCC>CCC	p.28_30PSP>P	PODXL_uc003vqx.3_In_Frame_Del_p.28_30PSP>P	NM_001018111	NP_001018121	O00592	PODXL_HUMAN	podocalyxin-like isoform 1 precursor	28_30	Extracellular (Potential).				cell adhesion|epithelial tube formation|negative regulation of cell-cell adhesion|positive regulation of cell migration|positive regulation of cell-cell adhesion mediated by integrin|regulation of microvillus assembly	actin cytoskeleton|apical plasma membrane|centrosome|filopodium|integral to plasma membrane|lamellipodium|membrane raft|microvillus membrane|nucleolus|ruffle				breast(2)|pancreas(1)	3	Melanoma(18;0.162)					ATTCTGGGAGggcgacggcgacggcg	0.573													4	9	---	---	---	---					
ODF1	4956	broad.mit.edu	37	8	103572984	103572992	+	In_Frame_Del	DEL	TGCAGCCCC	-	-	rs72175040	byFrequency	TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chr8:103572984_103572992delTGCAGCCCC	uc003ykt.2	+	2	733_741	c.625_633delTGCAGCCCC	c.(625-633)TGCAGCCCCdel	p.CSP215del		NM_024410	NP_077721	Q14990	ODFP1_HUMAN	outer dense fiber of sperm tails 1	215_217	C-X-P repeat region.				cell differentiation|multicellular organismal development|spermatogenesis	outer dense fiber	structural molecule activity			ovary(2)	2	all_cancers(14;2.76e-05)|all_epithelial(15;4.54e-08)|Lung NSC(17;4.08e-05)|all_lung(17;9.15e-05)		OV - Ovarian serous cystadenocarcinoma(57;0.000125)|STAD - Stomach adenocarcinoma(118;0.0826)			CACTTCTCCTtgcagcccctgcagcccct	0.364													7	59	---	---	---	---					
Unknown	0	broad.mit.edu	37	M	14074	14075	+	RNA	INS	-	A	A			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chrM:14074_14075insA	uc004cox.3	+	1		c.1738_1739insA			uc004coy.2_5'Flank|uc004coz.1_5'Flank					Homo sapiens NADH dehydrogenase subunit 5 (MTND5) mRNA, RNA 5, complete cds; mitochondrial gene for mitochondrial product.																		TCACCTCAACCCAAAAAGGCAT	0.416													29	1	---	---	---	---					
MCTS1	28985	broad.mit.edu	37	X	119739292	119739293	+	Frame_Shift_Ins	INS	-	AT	AT			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chrX:119739292_119739293insAT	uc004esx.2	+	2	390_391	c.42_43insAT	c.(40-45)TGCATCfs	p.C14fs	MCTS1_uc011mub.1_Frame_Shift_Ins_p.C15fs	NM_014060	NP_054779	Q9ULC4	MCTS1_HUMAN	malignant T cell amplified sequence 1 isoform 1	14_15					cell cycle|positive regulation of cell proliferation|regulation of growth|regulation of transcription, DNA-dependent|response to DNA damage stimulus|transcription, DNA-dependent	cytoplasm	RNA binding				0						TGTCCAACTGCATCCAGTTGAA	0.332													28	101	---	---	---	---					
STAG2	10735	broad.mit.edu	37	X	123184115	123184118	+	Frame_Shift_Del	DEL	AATG	-	-			TCGA-BQ-5875-01A-11D-1589-08	TCGA-BQ-5875-11A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	1f52ff0c-1578-4669-ad59-9130f5d4d0e6	f76f9283-5634-45e1-a751-f3275a7a0d7e	g.chrX:123184115_123184118delAATG	uc004etz.3	+	10	1312_1315	c.973_976delAATG	c.(973-978)AATGACfs	p.N325fs	STAG2_uc004eua.2_Frame_Shift_Del_p.N325fs|STAG2_uc004eub.2_Frame_Shift_Del_p.N325fs|STAG2_uc004euc.2_Frame_Shift_Del_p.N325fs|STAG2_uc004eud.2_Frame_Shift_Del_p.N325fs|STAG2_uc004eue.2_Frame_Shift_Del_p.N325fs	NM_006603	NP_006594	Q8N3U4	STAG2_HUMAN	stromal antigen 2 isoform b	325_326	SCD.				cell division|meiosis|mitotic metaphase/anaphase transition|mitotic prometaphase|negative regulation of DNA endoreduplication|sister chromatid cohesion	chromatin|chromosome, centromeric region|nucleoplasm	protein binding			ovary(4)|skin(1)	5						TGCCTTTCTTAATGACAGTTATTT	0.412													61	120	---	---	---	---					
