Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
RNF115	27246	broad.mit.edu	37	1	145688091	145688091	+	Missense_Mutation	SNP	T	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr1:145688091T>A	uc001eoj.2	+	9	990	c.786T>A	c.(784-786)CAT>CAA	p.H262Q	NBPF10_uc001emp.3_Intron|RNF115_uc001eok.2_Missense_Mutation_p.H229Q|RNF115_uc009wiy.2_Missense_Mutation_p.H181Q	NM_014455	NP_055270	Q9Y4L5	RN115_HUMAN	Rabring 7	262	RING-type.				protein autoubiquitination	cytosol	protein binding|ubiquitin-protein ligase activity|zinc ion binding			ovary(1)	1						TGTTTCAGCATGACACATGTC	0.418000													37	76					0	0	0.010771	0	0
ANP32E	81611	broad.mit.edu	37	1	150201557	150201557	+	Missense_Mutation	SNP	T	G	G			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr1:150201557T>G	uc001etw.2	-	4	711	c.341A>C	c.(340-342)AAT>ACT	p.N114T	ANP32E_uc010pbt.1_5'Flank|ANP32E_uc010pbu.1_Missense_Mutation_p.N66T|ANP32E_uc010pbv.1_Missense_Mutation_p.N73T|ANP32E_uc001etv.3_Missense_Mutation_p.N114T|ANP32E_uc010pbw.1_Intron	NM_030920	NP_112182	Q9BTT0	AN32E_HUMAN	acidic (leucine-rich) nuclear phosphoprotein 32	114						cytoplasmic membrane-bounded vesicle|nucleus	phosphatase inhibitor activity				0	Lung NSC(24;7.29e-29)|Breast(34;0.00211)|Ovarian(49;0.0167)|all_hematologic(923;0.0597)|Hepatocellular(266;0.161)|Colorectal(459;0.171)		LUSC - Lung squamous cell carcinoma(543;0.171)			ACTTTTCAAATTTTTAAGATT	0.244000													18	24					0	0	0.008871	0	0
NHLH1	4807	broad.mit.edu	37	1	160340735	160340735	+	Missense_Mutation	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr1:160340735G>A	uc001fwa.2	+	2	656	c.214G>A	c.(214-216)GCC>ACC	p.A72T		NM_005598	NP_005589	Q02575	HEN1_HUMAN	nescient helix loop helix 1	72					cell differentiation|central nervous system development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding			ovary(1)	1	all_cancers(52;7.11e-19)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)			ccggcgccgcgccACAGCCAA	0.622000													4	11					0	0	0.009096	0	0
ARHGAP30	257106	broad.mit.edu	37	1	161021130	161021130	+	Missense_Mutation	SNP	C	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr1:161021130C>A	uc001fxl.2	-	10	1740	c.1394G>T	c.(1393-1395)GGC>GTC	p.G465V	ARHGAP30_uc001fxk.2_Missense_Mutation_p.G465V|ARHGAP30_uc001fxm.2_Missense_Mutation_p.G311V|ARHGAP30_uc009wtx.2_Missense_Mutation_p.G138V|ARHGAP30_uc001fxn.1_Missense_Mutation_p.G311V	NM_001025598	NP_001020769	Q7Z6I6	RHG30_HUMAN	Rho GTPase activating protein 30 isoform 1	465					regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity			ovary(2)|upper_aerodigestive_tract(1)	3	all_cancers(52;8.05e-20)|Breast(13;0.00188)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.00122)			aaggccagggccagggccagg	0.418000													19	30					2.35188e-11	2.91633e-11	0.006122	1	0
ANK3	288	broad.mit.edu	37	10	61836183	61836183	+	Missense_Mutation	SNP	T	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr10:61836183T>C	uc001jky.2	-	37	4648	c.4456A>G	c.(4456-4458)AGA>GGA	p.R1486G	ANK3_uc001jkw.2_Intron|ANK3_uc009xpa.2_Intron|ANK3_uc001jkx.2_Intron|ANK3_uc010qih.1_Intron|ANK3_uc001jkz.3_Intron|ANK3_uc001jkv.2_Intron|ANK3_uc009xpb.1_Intron|ANK3_uc009xpc.1_RNA	NM_020987	NP_066267	Q12955	ANK3_HUMAN	ankyrin 3 isoform 1	1486					establishment of protein localization|signal transduction	basolateral plasma membrane|cytoplasm|cytoskeleton	protein binding			skin(9)|ovary(6)|pancreas(2)|central_nervous_system(2)	19						GGGAGGGATCTTGTTGCTCCT	0.418000													19	23					0	0	0.012319	0	0
ZMYND17	118490	broad.mit.edu	37	10	75185676	75185676	+	Missense_Mutation	SNP	C	T	T	rs143815503	byFrequency	TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr10:75185676C>T	uc001jud.2	-	5	1028	c.962G>A	c.(961-963)GGC>GAC	p.G321D	ZMYND17_uc001juc.2_Missense_Mutation_p.G321D|ZMYND17_uc009xrh.2_Missense_Mutation_p.G344D|ZMYND17_uc009xrg.2_Missense_Mutation_p.G100D	NM_001024593	NP_001019764	Q4VC12	ZMY17_HUMAN	zinc finger, MYND domain containing 17	321							zinc ion binding			ovary(1)	1	Prostate(51;0.0119)					CTGAATTGTGCCAGGTTCCAG	0.547000													3	51					0	0	0.009096	0	0
IFIT1B	439996	broad.mit.edu	37	10	91143275	91143275	+	Missense_Mutation	SNP	G	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr10:91143275G>C	uc001kgh.2	+	2	285	c.205G>C	c.(205-207)GAG>CAG	p.E69Q	LIPA_uc001kgb.3_Intron|LIPA_uc001kgc.3_Intron	NM_001010987	NP_001010987	Q5T764	IFT1B_HUMAN	interferon-induced protein with	69	TPR 1.|Potential.						binding				0						AGGCCAGAATGAGGAAGCCCT	0.448000													3	116					0	0	0.004672	0	0
MALAT1	378938	broad.mit.edu	37	11	65270998	65270998	+	RNA	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr11:65270998G>A	uc010roh.1	+	1		c.5766G>A			uc001ody.2_RNA|MALAT1_uc001odz.2_RNA	NR_002819				Homo sapiens clone alpha1 mRNA sequence.												0						ATGATGTGCTGTTAGAATCAG	0.303000													9	121					0	0	0.010729	0	0
GUCY2C	2984	broad.mit.edu	37	12	14796597	14796597	+	Missense_Mutation	SNP	C	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr12:14796597C>T	uc001rcd.2	-	17	1978	c.1841G>A	c.(1840-1842)CGT>CAT	p.R614H		NM_004963	NP_004954	P25092	GUC2C_HUMAN	guanylate cyclase 2C precursor	614	Cytoplasmic (Potential).|Protein kinase.				intracellular signal transduction|receptor guanylyl cyclase signaling pathway	integral to membrane	ATP binding|GTP binding|guanylate cyclase activity|protein binding|protein kinase activity|receptor activity			ovary(4)|skin(2)	6						AGATTTCAGACGACCATGGAC	0.398000													45	143					0	0	0.011902	0	0
KDM2B	84678	broad.mit.edu	37	12	121947832	121947832	+	Silent	SNP	C	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr12:121947832C>T	uc001uat.2	-	11	1289	c.1185G>A	c.(1183-1185)AGG>AGA	p.R395R	KDM2B_uc001uar.2_5'UTR|KDM2B_uc001uas.2_Silent_p.R364R|KDM2B_uc001uau.2_Silent_p.R278R|KDM2B_uc001uav.3_Silent_p.R305R	NM_032590	NP_115979	Q8NHM5	KDM2B_HUMAN	F-box and leucine-rich repeat protein 10 isoform	395					embryonic camera-type eye morphogenesis|fourth ventricle development|histone H2A monoubiquitination|initiation of neural tube closure|lateral ventricle development|midbrain development|midbrain-hindbrain boundary morphogenesis|negative regulation of neural precursor cell proliferation|negative regulation of neuron apoptosis|negative regulation of transcription from RNA polymerase II promoter|spermatogenesis|third ventricle development|transcription, DNA-dependent	nucleolus	DNA binding|histone demethylase activity (H3-K36 specific)|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|protein binding|rRNA binding|zinc ion binding			ovary(1)|skin(1)	2						TGCTGGGCTTCCTCGGGGCAT	0.493000													19	35					0	0	0.012319	0	0
SACS	26278	broad.mit.edu	37	13	23909472	23909472	+	Missense_Mutation	SNP	A	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr13:23909472A>T	uc001uon.2	-	10	9132	c.8543T>A	c.(8542-8544)TTC>TAC	p.F2848Y	SACS_uc001uoo.2_Missense_Mutation_p.F2701Y|SACS_uc001uop.1_Intron|SACS_uc001uoq.1_Intron	NM_014363	NP_055178	Q9NZJ4	SACS_HUMAN	sacsin	2848					cell death|negative regulation of inclusion body assembly|protein folding	axon|cell body fiber|dendrite|mitochondrion|nucleus	ATP binding|chaperone binding|Hsp70 protein binding|proteasome binding			ovary(7)|skin(2)|upper_aerodigestive_tract(1)|large_intestine(1)|pancreas(1)	12		all_cancers(29;1.51e-22)|all_epithelial(30;7.82e-19)|all_lung(29;4.71e-18)|Lung SC(185;0.0225)|Breast(139;0.128)		all cancers(112;0.00197)|Epithelial(112;0.00854)|OV - Ovarian serous cystadenocarcinoma(117;0.0298)|Lung(94;0.189)		ACCACGTGGGAAAAGAGTAAT	0.408000													47	81					0	0	0.014410	0	0
B3GALTL	145173	broad.mit.edu	37	13	31821210	31821210	+	Silent	SNP	A	G	G			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr13:31821210A>G	uc010aaz.2	+	5	431	c.321A>G	c.(319-321)GCA>GCG	p.A107A		NM_194318	NP_919299	Q6Y288	B3GLT_HUMAN	beta 1,3-galactosyltransferase-like	107	Lumenal (Potential).				fucose metabolic process	endoplasmic reticulum membrane|integral to membrane	transferase activity, transferring glycosyl groups			ovary(2)	2		Lung SC(185;0.0257)		all cancers(112;0.00436)|Epithelial(112;0.0285)|OV - Ovarian serous cystadenocarcinoma(117;0.0512)|GBM - Glioblastoma multiforme(144;0.184)		AAGAAGGTGCATGGACCATAC	0.418000													24	57					0	0	0.003954	0	0
ZFP106	64397	broad.mit.edu	37	15	42717056	42717056	+	Missense_Mutation	SNP	A	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr15:42717056A>C	uc001zpw.2	-	13	5432	c.5097T>G	c.(5095-5097)CAT>CAG	p.H1699Q	ZFP106_uc001zpu.2_Missense_Mutation_p.H797Q|ZFP106_uc001zpv.2_Missense_Mutation_p.H884Q|ZFP106_uc001zpx.2_Missense_Mutation_p.H927Q	NM_022473	NP_071918	Q9H2Y7	ZF106_HUMAN	zinc finger protein 106 homolog	1699	WD 4.					nucleolus	zinc ion binding			central_nervous_system(2)|ovary(1)	3		all_cancers(109;1.63e-12)|all_epithelial(112;3.97e-11)|Lung NSC(122;2.04e-07)|all_lung(180;8.31e-07)|Melanoma(134;0.091)		GBM - Glioblastoma multiforme(94;8.6e-07)		TGGTTTTGCTATGGCCCTCCA	0.443000													14	14					0	0	0.001855	0	0
KIAA1199	57214	broad.mit.edu	37	15	81230320	81230320	+	Missense_Mutation	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr15:81230320G>A	uc002bfw.1	+	24	3667	c.3407G>A	c.(3406-3408)GGG>GAG	p.G1136E	KIAA1199_uc010unn.1_Missense_Mutation_p.G1136E	NM_018689	NP_061159	Q8WUJ3	K1199_HUMAN	KIAA1199 precursor	1136										upper_aerodigestive_tract(1)|ovary(1)|skin(1)	3						GAGGACTCAGGGTGAGCAGGC	0.547000													9	10					0	0	0.010729	0	0
AXIN1	8312	broad.mit.edu	37	16	354433	354433	+	Silent	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr16:354433G>A	uc002cgp.1	-	5	1302	c.1125C>T	c.(1123-1125)TAC>TAT	p.Y375Y	AXIN1_uc002cgq.1_Silent_p.Y375Y	NM_003502	NP_003493	O15169	AXIN1_HUMAN	axin 1 isoform a	375	Interaction with GSK3B (By similarity).				activation of JUN kinase activity|activation of protein kinase activity|apoptosis|axial mesoderm formation|canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation|cellular protein complex assembly|cellular response to organic cyclic compound|cytoplasmic microtubule organization|determination of left/right symmetry|dorsal/ventral axis specification|embryonic eye morphogenesis|embryonic skeletal joint morphogenesis|forebrain anterior/posterior pattern formation|muscle cell development|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of fat cell differentiation|olfactory placode formation|optic placode formation|positive regulation of JNK cascade|positive regulation of peptidyl-serine phosphorylation|positive regulation of peptidyl-threonine phosphorylation|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of transcription, DNA-dependent|positive regulation of ubiquitin-protein ligase activity|regulation of catenin import into nucleus|tail morphogenesis|Wnt receptor signaling pathway involved in forebrain neuron fate commitment|Wnt receptor signaling pathway involved in somitogenesis	APC-Axin-1-beta-catenin complex|Axin-APC-beta-catenin-GSK3B complex|beta-catenin destruction complex|cell cortex|cytoplasmic membrane-bounded vesicle|cytoplasmic microtubule|cytosol|lateral plasma membrane|nucleus|perinuclear region of cytoplasm|postsynaptic density	armadillo repeat domain binding|beta-catenin binding|GTPase activator activity|I-SMAD binding|p53 binding|protein complex scaffold|protein homodimerization activity|protein kinase binding|signal transducer activity|ubiquitin protein ligase binding			breast(1)|liver(1)	2		all_cancers(16;2.75e-07)|all_epithelial(16;1.6e-06)|Hepatocellular(16;0.000105)|Lung NSC(18;0.00774)|all_lung(18;0.0187)				TCGGCACCCGGTACGTGCGCT	0.617000													3	35					0	0	0.004672	0	0
FBRS	64319	broad.mit.edu	37	16	30676958	30676958	+	Splice_Site	SNP	G	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr16:30676958G>C	uc002dzd.3	+	5	408	c.145_splice	c.e5-1	p.S49_splice	FBRS_uc002dzc.3_Intron	NM_001105079	NP_001098549	Q9HAH7	FBRS_HUMAN	fibrosin											ovary(1)	1			Colorectal(24;0.103)			CCCTTTCCCAGAGCACGAACC	0.652000													2	7					0	0	0.004672	0	0
KRT14	3861	broad.mit.edu	37	17	39742796	39742796	+	Silent	SNP	A	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr17:39742796A>C	uc002hxf.1	-	1	352	c.291T>G	c.(289-291)GGT>GGG	p.G97G	JUP_uc010wfs.1_Intron|KRT14_uc010cxp.1_Silent_p.G97G	NM_000526	NP_000517	P02533	K1C14_HUMAN	keratin 14	97	Head.				epidermis development|hemidesmosome assembly|intermediate filament bundle assembly	cytosol|keratin filament|mitochondrion|nucleus	protein binding|structural constituent of cytoskeleton			ovary(1)	1		Breast(137;0.000307)				caaagccaccacccaagccag	0.353000													8	43					0	0	0.007413	0	0
ABCA5	23461	broad.mit.edu	37	17	67283846	67283846	+	Missense_Mutation	SNP	C	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr17:67283846C>T	uc002jif.2	-	14	3167	c.1949G>A	c.(1948-1950)CGA>CAA	p.R650Q	ABCA5_uc002jic.2_5'Flank|ABCA5_uc002jid.2_5'UTR|ABCA5_uc002jie.2_RNA|ABCA5_uc002jig.2_Missense_Mutation_p.R650Q|ABCA5_uc002jih.2_Missense_Mutation_p.R650Q|ABCA5_uc010dfe.2_Missense_Mutation_p.R650Q	NM_018672	NP_061142	Q8WWZ7	ABCA5_HUMAN	ATP-binding cassette, sub-family A , member 5	650	ABC transporter 1.				cholesterol efflux|high-density lipoprotein particle remodeling|negative regulation of macrophage derived foam cell differentiation	Golgi membrane|integral to membrane|late endosome membrane|lysosomal membrane	ATP binding|ATPase activity			ovary(2)|central_nervous_system(1)|skin(1)	4	Breast(10;3.72e-11)					TACAATATGTCGAGAACAGGG	0.408000													89	78					0	0	0.014410	0	0
POLRMT	5442	broad.mit.edu	37	19	621842	621842	+	Missense_Mutation	SNP	C	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr19:621842C>T	uc002lpf.1	-	10	1912	c.1856G>A	c.(1855-1857)GGC>GAC	p.G619D		NM_005035	NP_005026	O00411	RPOM_HUMAN	mitochondrial DNA-directed RNA polymerase	619					transcription initiation from mitochondrial promoter	mitochondrial nucleoid	DNA binding|DNA-directed RNA polymerase activity|protein binding			ovary(1)|pancreas(1)	2		all_epithelial(18;2.78e-22)|Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;3.55e-06)|all_lung(49;5.41e-06)|Breast(49;4.08e-05)|Hepatocellular(1079;0.137)|Renal(1328;0.228)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CTTCAGGATGCCGATCTGGGG	0.687000													3	23					0	0	0.004672	0	0
RAB3A	5864	broad.mit.edu	37	19	18313494	18313494	+	Missense_Mutation	SNP	G	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr19:18313494G>C	uc002nie.2	-	2	226	c.57C>G	c.(55-57)TTC>TTG	p.F19L		NM_002866	NP_002857	P20336	RAB3A_HUMAN	RAB3A, member RAS oncogene family	19					glutamate secretion|protein transport|small GTPase mediated signal transduction	clathrin sculpted acetylcholine transport vesicle membrane|clathrin sculpted gamma-aminobutyric acid transport vesicle membrane|clathrin sculpted glutamate transport vesicle membrane|clathrin sculpted monoamine transport vesicle membrane|plasma membrane|synaptic vesicle	GTP binding|GTPase activity				0						ACATGTAGTCGAAGTTCTGAT	0.582000											OREG0025360	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	44	112					0	0	0.014410	0	0
ZNF155	7711	broad.mit.edu	37	19	44501505	44501505	+	Missense_Mutation	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr19:44501505G>A	uc002oxy.1	+	5	1701	c.1496G>A	c.(1495-1497)CGT>CAT	p.R499H	ZNF155_uc002oxz.1_Missense_Mutation_p.R499H|ZNF155_uc010xwt.1_Missense_Mutation_p.R510H|uc010ejc.1_RNA	NM_003445	NP_003436	Q12901	ZN155_HUMAN	zinc finger protein 155	499	C2H2-type 12; degenerate.					nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			large_intestine(1)|ovary(1)	2		Prostate(69;0.0352)				AGGACATACCGTAAAGACCAG	0.453000													4	92					0	0	0.009096	0	0
VPS54	51542	broad.mit.edu	37	2	64199372	64199372	+	Nonsense_Mutation	SNP	T	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr2:64199372T>A	uc002scq.2	-	4	548	c.385A>T	c.(385-387)AAG>TAG	p.K129*	VPS54_uc002scp.2_Nonsense_Mutation_p.K117*|VPS54_uc010fct.2_Nonsense_Mutation_p.K12*	NM_016516	NP_057600	Q9P1Q0	VPS54_HUMAN	vacuolar protein sorting 54 isoform 1	129					protein transport|retrograde transport, endosome to Golgi						0						TCATGAATCTTCTCTCTCTAA	0.303000													19	36					0	0	0.008871	0	0
ARID5A	10865	broad.mit.edu	37	2	97216937	97216937	+	Silent	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr2:97216937G>A	uc002swe.2	+	7	772	c.672G>A	c.(670-672)GGG>GGA	p.G224G	ARID5A_uc010yuq.1_Silent_p.G172G|ARID5A_uc002swf.2_Silent_p.G60G|ARID5A_uc002swg.2_Silent_p.G172G	NM_212481	NP_997646	Q03989	ARI5A_HUMAN	AT rich interactive domain 5A	224					negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleolus	DNA binding				0						TGGCCTCTGGGTCTTCTGTGT	0.602000													24	66					0	0	0.003954	0	0
CNNM4	26504	broad.mit.edu	37	2	97427340	97427340	+	Missense_Mutation	SNP	C	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr2:97427340C>A	uc002swx.2	+	1	702	c.604C>A	c.(604-606)CTC>ATC	p.L202I		NM_020184	NP_064569	Q6P4Q7	CNNM4_HUMAN	cyclin M4	202	DUF21.				biomineral tissue development|ion transport|response to stimulus|visual perception	integral to membrane|plasma membrane				breast(2)|ovary(1)	3						ATTTTCTGGCCTCAACCTCGG	0.587000													39	69					9.62906e-15	1.21837e-14	0.006230	1	0
CSNK2A1	1457	broad.mit.edu	37	20	468205	468205	+	Missense_Mutation	SNP	C	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr20:468205C>T	uc002wdw.1	-	12	1232	c.839G>A	c.(838-840)CGA>CAA	p.R280Q	CSNK2A1_uc002wdx.1_Missense_Mutation_p.R280Q|CSNK2A1_uc002wdy.1_Missense_Mutation_p.R144Q	NM_177559	NP_808227	P68400	CSK21_HUMAN	casein kinase II alpha 1 subunit isoform a	280	Protein kinase.				axon guidance|Wnt receptor signaling pathway	cytosol|NuRD complex|plasma membrane|Sin3 complex	ATP binding|protein N-terminus binding|protein serine/threonine kinase activity			ovary(1)	1		Breast(17;0.231)	OV - Ovarian serous cystadenocarcinoma(29;0.0969)			GCGTTCCCATCGCTTTCGAGA	0.502000													18	39					0	0	0.007413	0	0
HMOX1	3162	broad.mit.edu	37	22	35779129	35779129	+	Missense_Mutation	SNP	G	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr22:35779129G>T	uc003ant.1	+	2	134	c.54G>T	c.(52-54)AAG>AAT	p.K18N		NM_002133	NP_002124	P09601	HMOX1_HUMAN	heme oxygenase (decyclizing) 1	18					angiogenesis|anti-apoptosis|cell death|cellular iron ion homeostasis|endothelial cell proliferation|erythrocyte homeostasis|heme catabolic process|heme oxidation|intracellular protein kinase cascade|low-density lipoprotein particle clearance|negative regulation of leukocyte migration|negative regulation of smooth muscle cell proliferation|positive regulation of chemokine biosynthetic process|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of smooth muscle cell proliferation|protein homooligomerization|regulation of transcription from RNA polymerase II promoter in response to oxidative stress|response to hydrogen peroxide|response to nicotine|smooth muscle hyperplasia|transmembrane transport|wound healing involved in inflammatory response	endoplasmic reticulum membrane|extracellular space|microsome	enzyme binding|heme binding|heme oxygenase (decyclizing) activity|protein homodimerization activity|signal transducer activity			ovary(1)	1					NADH(DB00157)	AGGCCCTGAAGGAGGCCACCA	0.577000													25	51					4.72057e-08	5.73874e-08	0.003954	1	0
SUN2	25777	broad.mit.edu	37	22	39146253	39146253	+	Missense_Mutation	SNP	A	G	G			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr22:39146253A>G	uc003awh.1	-	6	781	c.497T>C	c.(496-498)CTC>CCC	p.L166P	SUN2_uc011anz.1_Missense_Mutation_p.L201P|SUN2_uc011aoa.1_Missense_Mutation_p.L155P|SUN2_uc003awi.1_Missense_Mutation_p.L166P|SUN2_uc010gxq.1_Missense_Mutation_p.L187P|SUN2_uc010gxr.1_Missense_Mutation_p.L166P|SUN2_uc010gxs.1_Missense_Mutation_p.L166P	NM_015374	NP_056189	Q9UH99	SUN2_HUMAN	unc-84 homolog B	166	Nuclear.				centrosome localization|cytoskeletal anchoring at nuclear membrane|mitotic spindle organization|nuclear envelope organization|nuclear matrix anchoring at nuclear membrane|nuclear migration along microfilament|positive regulation of cell migration	endosome membrane|integral to membrane|nuclear inner membrane|SUN-KASH complex	lamin binding|microtubule binding			large_intestine(1)|skin(1)	2						CACCATCCAGAGTAAGGAGCC	0.602000													20	30					0	0	0.008871	0	0
PSMD6	9861	broad.mit.edu	37	3	64004274	64004274	+	Splice_Site	SNP	C	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr3:64004274C>A	uc003dma.1	-	5	851	c.826_splice	c.e5+1	p.A276_splice	PSMD6_uc003dlz.1_Splice_Site_p.A227_splice|PSMD6_uc003dmb.1_Splice_Site_p.A329_splice|PSMD6_uc003dmc.1_Splice_Site_p.A237_splice|PSMD6_uc003dmd.1_Splice_Site_p.A238_splice	NM_014814	NP_055629	Q15008	PSMD6_HUMAN	proteasome (prosome, macropain) 26S subunit,						anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|mRNA metabolic process|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|regulation of apoptosis|regulation of cellular amino acid metabolic process|S phase of mitotic cell cycle|viral reproduction	proteasome complex	ATPase activity|protein binding			central_nervous_system(1)|skin(1)	2		Lung NSC(201;0.136)		BRCA - Breast invasive adenocarcinoma(55;0.000805)|Kidney(15;0.00188)|KIRC - Kidney renal clear cell carcinoma(15;0.00212)		CCTATCCTTACCTAATGATTG	0.388000													10	19					0.000673444	0.000802952	0.008291	1	0
EPHA6	285220	broad.mit.edu	37	3	97202865	97202865	+	Missense_Mutation	SNP	A	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr3:97202865A>C	uc010how.1	+	10	2205	c.2162A>C	c.(2161-2163)GAT>GCT	p.D721A	EPHA6_uc011bgo.1_RNA|EPHA6_uc011bgp.1_Missense_Mutation_p.D87A|EPHA6_uc003drs.3_Missense_Mutation_p.D113A|EPHA6_uc003drr.3_Missense_Mutation_p.D113A|EPHA6_uc003drt.2_Missense_Mutation_p.D113A|EPHA6_uc010hox.1_RNA	NM_001080448	NP_001073917	Q9UF33	EPHA6_HUMAN	EPH receptor A6 isoform a	626	Cytoplasmic (Potential).					integral to plasma membrane	ATP binding|ephrin receptor activity			stomach(5)|lung(4)|central_nervous_system(3)|breast(1)|skin(1)|ovary(1)|kidney(1)	16						AAGGAGATTGATCCCTCAAGA	0.303000													25	16					0	0	0.003330	0	0
PHC3	80012	broad.mit.edu	37	3	169847187	169847187	+	Missense_Mutation	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr3:169847187G>A	uc010hws.1	-	8	1101	c.1037C>T	c.(1036-1038)CCA>CTA	p.P346L	PHC3_uc003fgl.2_Missense_Mutation_p.P358L|PHC3_uc011bpq.1_Missense_Mutation_p.P305L|PHC3_uc011bpr.1_Missense_Mutation_p.P272L	NM_024947	NP_079223	Q8NDX5	PHC3_HUMAN	polyhomeotic like 3	346	Pro-rich.|Gln-rich.				multicellular organismal development	PcG protein complex	DNA binding|zinc ion binding			ovary(1)|central_nervous_system(1)	2	all_cancers(22;2.67e-22)|all_epithelial(15;4.73e-27)|all_lung(20;6.31e-17)|Lung NSC(18;2.61e-16)|Ovarian(172;0.000337)|Breast(254;0.169)		Lung(28;2.71e-13)|STAD - Stomach adenocarcinoma(35;0.0655)			GGATGGGGGTGGGTCTTGAGT	0.488000													42	91					0	0	0.007835	0	0
PDGFRA	5156	broad.mit.edu	37	4	55139834	55139834	+	Missense_Mutation	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr4:55139834G>A	uc003han.3	+	10	1826	c.1495G>A	c.(1495-1497)GTG>ATG	p.V499M	PDGFRA_uc003haa.2_Intron|PDGFRA_uc010igq.1_Missense_Mutation_p.V393M|PDGFRA_uc003ham.2_RNA	NM_006206	NP_006197	P16234	PGFRA_HUMAN	platelet-derived growth factor receptor alpha	499	Ig-like C2-type 5.|Extracellular (Potential).				cardiac myofibril assembly|cell activation|luteinization|metanephric glomerular capillary formation|peptidyl-tyrosine phosphorylation|positive regulation of cell migration|positive regulation of DNA replication|positive regulation of fibroblast proliferation|protein autophosphorylation|retina vasculature development in camera-type eye	cytoplasm|integral to plasma membrane|nucleus	ATP binding|platelet-derived growth factor alpha-receptor activity|platelet-derived growth factor binding|platelet-derived growth factor receptor binding|protein homodimerization activity|vascular endothelial growth factor receptor activity			soft_tissue(572)|small_intestine(40)|stomach(16)|lung(16)|central_nervous_system(13)|haematopoietic_and_lymphoid_tissue(7)|skin(3)|ovary(3)|gastrointestinal_tract_(site_indeterminate)(1)|autonomic_ganglia(1)|prostate(1)|bone(1)	674	all_cancers(7;0.000425)|all_lung(4;0.000343)|Lung NSC(11;0.000467)|all_epithelial(27;0.0131)|all_neural(26;0.0209)|Glioma(25;0.08)		GBM - Glioblastoma multiforme(1;4.18e-71)|all cancers(1;4.76e-45)|LUSC - Lung squamous cell carcinoma(32;0.00256)		Becaplermin(DB00102)|Imatinib(DB00619)|Sunitinib(DB01268)	GACCATCGCCGTGCGATGCCT	0.557000			Mis|O|T	FIP1L1	GIST|idiopathic hypereosinophilic syndrome				Gastrointestinal_Stromal_Tumors_Sporadic_Multiple_Primary|Familial_Intestinal_Neurofibromatosis	TSP Lung(21;0.16)			19	45					0	0	0.010504	0	0
LPCAT1	79888	broad.mit.edu	37	5	1488543	1488543	+	Silent	SNP	A	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr5:1488543A>T	uc003jcm.2	-	5	747	c.630T>A	c.(628-630)ACT>ACA	p.T210T		NM_024830	NP_079106	Q8NF37	PCAT1_HUMAN	lysophosphatidylcholine acyltransferase 1	210	Lumenal (Potential).				phospholipid biosynthetic process	endoplasmic reticulum membrane|Golgi membrane|integral to membrane	1-acylglycerophosphocholine O-acyltransferase activity|1-alkylglycerophosphocholine O-acetyltransferase activity|calcium ion binding			ovary(2)	2			OV - Ovarian serous cystadenocarcinoma(19;0.0274)|all cancers(22;0.0534)	GBM - Glioblastoma multiforme(108;0.156)		TGTTTGTACAAGTTCCTTCTG	0.323000													37	51					0	0	0.008740	0	0
NSUN2	54888	broad.mit.edu	37	5	6620280	6620280	+	Missense_Mutation	SNP	C	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr5:6620280C>T	uc003jdu.2	-	7	819	c.754G>A	c.(754-756)GAT>AAT	p.D252N	NSUN2_uc003jdt.2_Missense_Mutation_p.D16N|NSUN2_uc011cmk.1_Missense_Mutation_p.D217N|NSUN2_uc003jdv.2_Missense_Mutation_p.D16N	NM_017755	NP_060225	Q08J23	NSUN2_HUMAN	NOL1/NOP2/Sun domain family, member 2	252						cytoplasm|nucleolus	tRNA (cytosine-5-)-methyltransferase activity|tRNA binding			ovary(1)	1						CCGTCCACATCTATCTGGAGC	0.493000													33	66					0	0	0.003271	0	0
VCAN	1462	broad.mit.edu	37	5	82836813	82836813	+	Missense_Mutation	SNP	A	G	G			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr5:82836813A>G	uc003kii.3	+	8	8347	c.7991A>G	c.(7990-7992)GAT>GGT	p.D2664G	VCAN_uc003kij.3_Missense_Mutation_p.D1677G|VCAN_uc010jau.2_Intron|VCAN_uc003kik.3_Intron|VCAN_uc003kil.3_Missense_Mutation_p.D1328G	NM_004385	NP_004376	P13611	CSPG2_HUMAN	versican isoform 1 precursor	2664	GAG-beta.				cell adhesion|cell recognition|glial cell migration	extracellular space|proteinaceous extracellular matrix	calcium ion binding|hyaluronic acid binding|sugar binding			ovary(7)|skin(6)|lung(2)|central_nervous_system(1)	16		Lung NSC(167;0.0216)|all_lung(232;0.0251)|Ovarian(174;0.142)		OV - Ovarian serous cystadenocarcinoma(54;2.47e-41)|Epithelial(54;2.51e-34)|all cancers(79;5.19e-29)		AGCCAACTAGATCACATGGGC	0.453000													38	103					0	0	0.006999	0	0
SLC22A5	6584	broad.mit.edu	37	5	131729504	131729504	+	Splice_Site	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr5:131729504G>A	uc003kww.3	+	9	1850	c.1586_splice	c.e9+1	p.G529_splice	SLC22A5_uc003kwx.3_Splice_Site_p.G553_splice	NM_003060	NP_003051	O76082	S22A5_HUMAN	solute carrier family 22 member 5						positive regulation of intestinal epithelial structure maintenance|quorum sensing involved in interaction with host|sodium ion transport|sodium-dependent organic cation transport	apical plasma membrane|brush border membrane|integral to membrane	ATP binding|carnitine transporter activity|PDZ domain binding|symporter activity				0		all_cancers(142;0.0751)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)		L-Carnitine(DB00583)	GAGTCAAAGGGTAAGAAGACC	0.542000													57	87					0	0	0.014410	0	0
PCDHB7	56129	broad.mit.edu	37	5	140553676	140553676	+	Silent	SNP	C	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr5:140553676C>T	uc003lit.2	+	1	1434	c.1260C>T	c.(1258-1260)ACC>ACT	p.T420T		NM_018940	NP_061763	Q9Y5E2	PCDB7_HUMAN	protocadherin beta 7 precursor	420	Extracellular (Potential).|Cadherin 4.				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(4)|central_nervous_system(1)|skin(1)	6			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			ACAACATCACCATCACCGTCA	0.512000													4	71					0	0	0.000602	0	0
PPP1R10	5514	broad.mit.edu	37	6	30577691	30577691	+	Missense_Mutation	SNP	G	T	T			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr6:30577691G>T	uc003nqn.1	-	3	583	c.31C>A	c.(31-33)CTT>ATT	p.L11I	PPP1R10_uc010jsc.1_5'UTR	NM_002714	NP_002705	Q96QC0	PP1RA_HUMAN	protein phosphatase 1, regulatory subunit 10	11	Interaction with TOX4 (By similarity).				protein import into nucleus|transcription, DNA-dependent	PTW/PP1 phosphatase complex	DNA binding|protein phosphatase inhibitor activity|RNA binding|zinc ion binding			ovary(2)|lung(1)|kidney(1)	4						CCCTTGAGAAGTTCTTTGGGG	0.468000													31	52					1.55811e-20	2.01256e-20	0.008361	1	0
URGCP	55665	broad.mit.edu	37	7	43918184	43918184	+	Missense_Mutation	SNP	A	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr7:43918184A>C	uc003tiw.2	-	6	935	c.878T>G	c.(877-879)TTC>TGC	p.F293C	URGCP_uc003tiu.2_Missense_Mutation_p.F250C|URGCP_uc003tiv.2_Missense_Mutation_p.F218C|URGCP_uc003tix.2_Missense_Mutation_p.F284C|URGCP_uc003tiy.2_Missense_Mutation_p.F250C|URGCP_uc003tiz.2_Missense_Mutation_p.F250C|URGCP_uc011kbj.1_Missense_Mutation_p.F250C	NM_001077663	NP_001071131	Q8TCY9	URGCP_HUMAN	up-regulated gene 4 isoform 3	293					cell cycle	centrosome|nucleus	GTP binding			ovary(2)|liver(1)|skin(1)	4						CCGATGCCAGAAGCAGTCCCA	0.602000													20	47					0	0	0.008871	0	0
BAZ1B	9031	broad.mit.edu	37	7	72907199	72907199	+	Silent	SNP	T	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr7:72907199T>C	uc003tyc.2	-	5	969	c.624A>G	c.(622-624)GGA>GGG	p.G208G		NM_032408	NP_115784	Q9UIG0	BAZ1B_HUMAN	bromodomain adjacent to zinc finger domain, 1B	208	Mediates the tyrosine-protein kinase activity.|C motif.				ATP-dependent chromatin remodeling|chromatin-mediated maintenance of transcription|DNA replication-dependent nucleosome disassembly|double-strand break repair|heart morphogenesis|transcription, DNA-dependent	WINAC complex	ATP binding|chromatin binding|histone acetyl-lysine binding|histone kinase activity|non-membrane spanning protein tyrosine kinase activity|protein complex scaffold|vitamin D receptor activator activity|vitamin D receptor binding|zinc ion binding			ovary(4)|upper_aerodigestive_tract(1)|breast(1)|skin(1)	7		Lung NSC(55;0.0659)|all_lung(88;0.152)				ATTTCCTTTCTCCTTTTTTTA	0.328000													23	77					0	0	0.002780	0	0
DNAJC2	27000	broad.mit.edu	37	7	102963052	102963053	+	Nonsense_Mutation	DNP	AT	TA	TA			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr7:102963052_102963053AT>TA	uc003vbo.2	-	9	1089_1090	c.838_839AT>TA	c.(838-840)ATA>TAA	p.I280*	PMPCB_uc011kll.1_Intron|DNAJC2_uc003vbn.2_5'UTR|DNAJC2_uc010lix.2_Nonsense_Mutation_p.I280*|DNAJC2_uc003vbp.2_5'UTR	NM_014377	NP_055192	Q99543	DNJC2_HUMAN	DnaJ (Hsp40) homolog, subfamily C, member 2	280					'de novo' cotranslational protein folding|chromatin modification|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|nuclear membrane	chromatin binding|DNA binding|histone binding|Hsp70 protein binding|ubiquitin binding			kidney(1)	1						GAACTTTTTTATCCTTGGATCA	0.173000													30	23					0	0	0.004672	0	0
PLEC	5339	broad.mit.edu	37	8	144997708	144997708	+	Missense_Mutation	SNP	T	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr8:144997708T>A	uc003zaf.1	-	31	6970	c.6800A>T	c.(6799-6801)CAG>CTG	p.Q2267L	PLEC_uc003zab.1_Missense_Mutation_p.Q2130L|PLEC_uc003zac.1_Missense_Mutation_p.Q2134L|PLEC_uc003zad.2_Missense_Mutation_p.Q2130L|PLEC_uc003zae.1_Missense_Mutation_p.Q2098L|PLEC_uc003zag.1_Missense_Mutation_p.Q2108L|PLEC_uc003zah.2_Missense_Mutation_p.Q2116L|PLEC_uc003zaj.2_Missense_Mutation_p.Q2157L	NM_201380	NP_958782	Q15149	PLEC_HUMAN	plectin isoform 1	2267	Central fibrous rod domain.|Potential.				cellular component disassembly involved in apoptosis|hemidesmosome assembly	cytosol|focal adhesion|hemidesmosome|intermediate filament cytoskeleton|sarcolemma	actin binding|structural constituent of muscle|structural constituent of muscle			large_intestine(2)|ovary(2)|pancreas(2)|upper_aerodigestive_tract(1)|central_nervous_system(1)|skin(1)	9						CGCCTGTGCCTGAGCCCGGGC	0.741000													4	14					0	0	0.000602	0	0
ABCA2	20	broad.mit.edu	37	9	139908396	139908396	+	Silent	SNP	G	C	C			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr9:139908396G>C	uc011mem.1	-	27	4480	c.4332C>G	c.(4330-4332)GTC>GTG	p.V1444V	ABCA2_uc011mel.1_Silent_p.V1445V|ABCA2_uc004ckl.1_Silent_p.V1375V|ABCA2_uc004ckm.1_Silent_p.V1475V|ABCA2_uc004ckn.1_RNA	NM_001606	NP_001597	Q9BZC7	ABCA2_HUMAN	ATP-binding cassette, sub-family A, member 2	1444					cholesterol homeostasis|lipid metabolic process|regulation of intracellular cholesterol transport|regulation of transcription from RNA polymerase II promoter|response to drug|response to steroid hormone stimulus	ATP-binding cassette (ABC) transporter complex|cytoplasmic membrane-bounded vesicle|endosome|integral to membrane|microtubule organizing center	ATP binding|ATPase activity, coupled to transmembrane movement of substances				0	all_cancers(76;0.16)	Myeloproliferative disorder(178;0.0511)	STAD - Stomach adenocarcinoma(284;0.123)	OV - Ovarian serous cystadenocarcinoma(145;2.94e-05)|Epithelial(140;0.00048)		GGAAGCGTTTGACCAGCAGCC	0.672000													10	17					0	0	0.008291	0	0
DDX3X	1654	broad.mit.edu	37	X	41202004	41202004	+	Missense_Mutation	SNP	G	A	A			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chrX:41202004G>A	uc004dfe.2	+	6	1313	c.458G>A	c.(457-459)GGA>GAA	p.G153E	DDX3X_uc010nhf.1_Missense_Mutation_p.G137E|DDX3X_uc004dff.2_Missense_Mutation_p.G153E|DDX3X_uc011mkq.1_Missense_Mutation_p.G137E|DDX3X_uc011mkr.1_Missense_Mutation_p.G153E|DDX3X_uc011mks.1_Intron|DDX3X_uc004dfg.2_RNA|DDX3X_uc011mkt.1_RNA	NM_001356	NP_001347	O00571	DDX3X_HUMAN	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3	153					interspecies interaction between organisms	cytoplasm|nuclear speck	ATP binding|ATP-dependent RNA helicase activity|DNA binding|protein binding|RNA binding			ovary(2)|breast(2)|central_nervous_system(1)|skin(1)	6						CTCTTTTCTGGAGGCAACACT	0.363000										HNSCC(61;0.18)			48	75					0	0	0.014410	0	0
CD86	942	broad.mit.edu	37	3	121825262	121825263	+	Frame_Shift_Del	DEL	AT	-	-			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr3:121825262_121825263delAT	uc003eet.2	+	4	734_735	c.618_619delAT	c.(616-621)TCATTCfs	p.S206fs	CD86_uc011bjo.1_Frame_Shift_Del_p.S124fs|CD86_uc011bjp.1_Frame_Shift_Del_p.S94fs|CD86_uc003eeu.2_Frame_Shift_Del_p.S200fs	NM_175862	NP_787058	P42081	CD86_HUMAN	CD86 antigen isoform 1	206_207	Ig-like C2-type.|Extracellular (Potential).				interspecies interaction between organisms|positive regulation of cell proliferation|positive regulation of interleukin-2 biosynthetic process|positive regulation of interleukin-4 biosynthetic process|positive regulation of lymphotoxin A biosynthetic process|positive regulation of T-helper 2 cell differentiation|positive regulation of transcription, DNA-dependent|T cell costimulation		coreceptor activity|protein binding			pancreas(1)|skin(1)	2				GBM - Glioblastoma multiforme(114;0.156)	Abatacept(DB01281)	TGTCTGTTTCATTCCCTGATGT	0.391													177	189	---	---	---	---					
CEP63	80254	broad.mit.edu	37	3	134250746	134250746	+	Frame_Shift_Del	DEL	G	-	-			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr3:134250746delG	uc003eqo.1	+	5	731	c.282delG	c.(280-282)ATGfs	p.M94fs	CEP63_uc003eql.1_Frame_Shift_Del_p.M94fs|CEP63_uc003eqm.2_Frame_Shift_Del_p.M94fs|CEP63_uc003eqn.1_Frame_Shift_Del_p.M94fs	NM_025180	NP_079456	Q96MT8	CEP63_HUMAN	centrosomal protein 63 isoform a	94	Potential.				cell division|DNA damage checkpoint|G2/M transition of mitotic cell cycle|mitosis|signal transduction in response to DNA damage|spindle assembly	centrosome|cytosol|spindle pole	protein binding			ovary(1)	1						AGATGACCATGGAATATAAGC	0.353													41	39	---	---	---	---					
CCDC129	223075	broad.mit.edu	37	7	31683522	31683527	+	In_Frame_Del	DEL	GACTTT	-	-			TCGA-EV-5901-01A-11D-1589-08	TCGA-EV-5901-10A-01D-1589-08									Somatic	Phase_I	Capture				Illumina GAIIx	846543e9-145b-4332-9043-5817b55e2208	8623db0f-675b-4d34-ba2b-5c12aa3e9b7b	g.chr7:31683522_31683527delGACTTT	uc003tcj.1	+	11	3531_3536	c.2538_2543delGACTTT	c.(2536-2544)ACGACTTTG>ACG	p.TL847del	CCDC129_uc011kad.1_In_Frame_Del_p.TL857del|CCDC129_uc003tci.1_In_Frame_Del_p.TL698del|CCDC129_uc011kae.1_In_Frame_Del_p.TL873del|CCDC129_uc003tck.1_In_Frame_Del_p.TL755del	NM_194300	NP_919276	Q6ZRS4	CC129_HUMAN	coiled-coil domain containing 129	847_848											0						AGTTCATGACGACTTTGAAAGCCCTT	0.549													26	98	---	---	---	---					
