Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
RSC1A1	6248	broad.mit.edu	37	1	15987648	15987648	+	Silent	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr1:15987648T>C	uc010obn.1	+	1	1285	c.1285T>C	c.(1285-1287)TTA>CTA	p.L429L		NM_006511	NP_006502	Q92681	RSCA1_HUMAN	regulatory solute carrier protein, family 1,	429					negative regulation of transport|regulation of transcription, DNA-dependent|transcription, DNA-dependent|transport	cell junction|Golgi apparatus|nucleus	ion channel inhibitor activity			ovary(1)	1		Colorectal(325;0.00108)|Renal(390;0.00145)|Breast(348;0.00276)|Lung NSC(340;0.00566)|all_lung(284;0.00831)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0798)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;5.73e-07)|COAD - Colon adenocarcinoma(227;3.49e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000114)|KIRC - Kidney renal clear cell carcinoma(229;0.00244)|STAD - Stomach adenocarcinoma(313;0.0072)|READ - Rectum adenocarcinoma(331;0.0649)		GACAGAAAAATTAACAGGTAC	0.433000													30	37					0	0	1	0	0
MST1P2	11209	broad.mit.edu	37	1	16974224	16974224	+	RNA	SNP	C	G	G	rs148702086	by1000genomes	TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr1:16974224C>G	uc009vow.2	+	5		c.1034C>G			MST1P2_uc010ocg.1_RNA|MST1P2_uc010och.1_Intron|MST1P2_uc010oci.1_RNA|MST1P2_uc001azk.2_Intron|MST1P2_uc001azl.3_RNA|MST1P2_uc009vox.2_Intron|MST1P2_uc001azm.3_Intron					Homo sapiens cDNA FLJ53774 complete cds, moderately similar to Hepatocyte growth factor-like protein precursor.												0						TTGGTCCCAGCCCCAGAGGGA	0.652000													5	20					0	0	1	0	0
PGM1	5236	broad.mit.edu	37	1	64117371	64117371	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr1:64117371G>A	uc001dbh.2	+	9	1525	c.1312G>A	c.(1312-1314)GCA>ACA	p.A438T	PGM1_uc010ooy.1_Missense_Mutation_p.A241T|PGM1_uc010ooz.1_Missense_Mutation_p.A456T	NM_002633	NP_002624	P36871	PGM1_HUMAN	phosphoglucomutase 1	438					cellular calcium ion homeostasis|galactose catabolic process|glucose 1-phosphate metabolic process|glycogen biosynthetic process|glycogen catabolic process	cytosol	magnesium ion binding|phosphoglucomutase activity			ovary(2)|kidney(1)	3						AGCTGAGGGCGCAAACAAAAT	0.512000													3	33					0	0	1	0	0
KIAA1614	57710	broad.mit.edu	37	1	180885553	180885553	+	Missense_Mutation	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr1:180885553C>T	uc001gok.2	+	2	381	c.314C>T	c.(313-315)TCT>TTT	p.S105F		NM_020950	NP_066001	Q5VZ46	K1614_HUMAN	hypothetical protein LOC57710	105										ovary(3)|skin(1)	4						AGTCCCTGCTCTGCTTCCCAA	0.587000													39	52					0	0	1	0	0
C1orf25	81627	broad.mit.edu	37	1	185094118	185094118	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr1:185094118T>A	uc001grf.3	-	12	1989	c.1717A>T	c.(1717-1719)AGT>TGT	p.S573C	C1orf25_uc010pon.1_Missense_Mutation_p.S417C	NM_030934	NP_112196	Q7Z2T5	TRM1L_HUMAN	N2,N2-dimethylguanosine tRNA	573						intracellular	RNA binding|tRNA (guanine-N2-)-methyltransferase activity|zinc ion binding				0						GAAAACTGACTTTGAGGCGTA	0.358000													35	59					0	0	1	0	0
C1orf150	148823	broad.mit.edu	37	1	247737622	247737622	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr1:247737622T>C	uc001idf.2	+	5	391	c.346T>C	c.(346-348)TCT>CCT	p.S116P	C1orf150_uc009xgw.2_RNA|C1orf150_uc001ida.3_RNA|C1orf150_uc001idb.3_RNA|C1orf150_uc009xgx.2_RNA	NM_145278	NP_660321	Q5JQS6	CA150_HUMAN	hypothetical protein LOC148823	116											0	all_cancers(71;3.24e-05)|all_epithelial(71;1.3e-05)|Breast(184;0.0149)|Ovarian(71;0.0377)|all_lung(81;0.0662)|Lung NSC(105;0.0724)		OV - Ovarian serous cystadenocarcinoma(106;0.0241)			TCTTAGGACTTCTGTTAGTAG	0.433000													32	49					0	0	1	0	0
GTPBP4	23560	broad.mit.edu	37	10	1061760	1061760	+	Missense_Mutation	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr10:1061760C>A	uc001ift.2	+	16	1747	c.1676C>A	c.(1675-1677)GCT>GAT	p.A559D	GTPBP4_uc001ifu.2_RNA|GTPBP4_uc010qad.1_Missense_Mutation_p.A443D|GTPBP4_uc010qae.1_Missense_Mutation_p.A512D	NM_012341	NP_036473	Q9BZE4	NOG1_HUMAN	G protein-binding protein CRFG	559					negative regulation of cell migration|negative regulation of cell proliferation|negative regulation of cell-cell adhesion|negative regulation of collagen binding|negative regulation of DNA replication|negative regulation of protein ubiquitination|protein stabilization|regulation of cyclin-dependent protein kinase activity|ribosome biogenesis	nucleolus|perinuclear region of cytoplasm	GTP binding|GTPase activity|protein binding			ovary(1)|skin(1)	2		all_epithelial(10;0.107)|Colorectal(49;0.14)	OV - Ovarian serous cystadenocarcinoma(33;0.0814)	Epithelial(11;0.0513)|all cancers(11;0.135)|OV - Ovarian serous cystadenocarcinoma(14;0.173)		GAAGACTCTGCTCCCCCGTCC	0.552000													52	99					1.07234e-20	1.21375e-20	1	1	0
KLF6	1316	broad.mit.edu	37	10	3822362	3822362	+	Missense_Mutation	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr10:3822362C>T	uc001iha.2	-	3	1003	c.736G>A	c.(736-738)GAG>AAG	p.E246K	KLF6_uc010qaj.1_Intron|KLF6_uc010qak.1_RNA|KLF6_uc010qal.1_Missense_Mutation_p.E204K	NM_001300	NP_001291	Q99612	KLF6_HUMAN	Kruppel-like factor 6 isoform A	246	C2H2-type 2.				B cell differentiation	nucleus	zinc ion binding			central_nervous_system(3)|lung(1)	4				Colorectal(1;0.238)		CTGGTTAACTCATCACTTCTT	0.542000													19	47					0	0	1	0	0
KIN	22944	broad.mit.edu	37	10	7829859	7829859	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr10:7829859G>C	uc001ijt.2	-	1	86	c.38C>G	c.(37-39)GCC>GGC	p.A13G	KIN_uc010qaz.1_RNA|KIN_uc009xip.2_Missense_Mutation_p.A13G|KIN_uc010qba.1_5'UTR|ATP5C1_uc010qbb.1_5'Flank|ATP5C1_uc009xiq.1_5'Flank|ATP5C1_uc010qbc.1_5'Flank|ATP5C1_uc001iju.2_5'Flank|ATP5C1_uc001ijv.2_5'Flank	NM_012311	NP_036443	O60870	KIN17_HUMAN	HsKin17 protein	13					DNA recombination|DNA repair|DNA replication|interspecies interaction between organisms|mRNA processing	cytoplasm|nuclear matrix	double-stranded DNA binding|RNA binding|zinc ion binding			ovary(1)|pancreas(1)|skin(1)	3						GATCCTGTTGGCGATAGCCTT	0.612000													54	67					0	0	1	0	0
MGEA5	10724	broad.mit.edu	37	10	103563517	103563517	+	Silent	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr10:103563517A>G	uc001ktv.2	-	7	1454	c.1011T>C	c.(1009-1011)AAT>AAC	p.N337N	MGEA5_uc010qqe.1_Silent_p.N337N|MGEA5_uc009xws.2_Silent_p.N337N|MGEA5_uc001ktw.2_Silent_p.N337N|MGEA5_uc009xwt.2_Intron	NM_012215	NP_036347	O60502	NCOAT_HUMAN	meningioma expressed antigen 5 (hyaluronidase)	337					glycoprotein catabolic process	cytoplasm|nucleus	histone acetyltransferase activity|hyalurononglucosaminidase activity			ovary(2)|skin(1)	3		Colorectal(252;0.207)		Epithelial(162;4.67e-09)|all cancers(201;2.54e-07)		TTCTCACTCCATTCATGTTTG	0.438000													9	102					0	0	1	0	0
DCHS1	8642	broad.mit.edu	37	11	6662595	6662595	+	Missense_Mutation	SNP	C	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr11:6662595C>G	uc001mem.1	-	2	660	c.250G>C	c.(250-252)GAG>CAG	p.E84Q		NM_003737	NP_003728	Q96JQ0	PCD16_HUMAN	dachsous 1 precursor	84	Cadherin 1.|Extracellular (Potential).				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(3)|large_intestine(1)|pancreas(1)	5		Medulloblastoma(188;0.00263)|all_neural(188;0.026)		Epithelial(150;6.35e-09)|BRCA - Breast invasive adenocarcinoma(625;0.135)		CCGCTGCCCTCTTGGGCAGAG	0.627000													16	25					0	0	1	0	0
OR5F1	338674	broad.mit.edu	37	11	55761615	55761615	+	Missense_Mutation	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr11:55761615C>T	uc010riv.1	-	1	487	c.487G>A	c.(487-489)GTC>ATC	p.V163I		NM_003697	NP_003688	O95221	OR5F1_HUMAN	olfactory receptor, family 5, subfamily F,	163	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|pancreas(1)	2	Esophageal squamous(21;0.00448)					AAGCTGCTGACATGGCTTGTG	0.483000													40	54					0	0	1	0	0
OR5F1	338674	broad.mit.edu	37	11	55761636	55761636	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr11:55761636A>C	uc010riv.1	-	1	466	c.466T>G	c.(466-468)TTC>GTC	p.F156V		NM_003697	NP_003688	O95221	OR5F1_HUMAN	olfactory receptor, family 5, subfamily F,	156	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|pancreas(1)	2	Esophageal squamous(21;0.00448)					TTGACCATGAAGTTCAGCAAC	0.507000													28	57					0	0	1	0	0
MYO7A	4647	broad.mit.edu	37	11	76903188	76903188	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr11:76903188C>T	uc001oyb.2	+	31	4289	c.4017C>T	c.(4015-4017)AAC>AAT	p.N1339N	MYO7A_uc010rsm.1_Silent_p.N1328N|MYO7A_uc001oyc.2_Silent_p.N1339N|MYO7A_uc009yus.1_RNA|MYO7A_uc009yut.1_Silent_p.N550N	NM_000260	NP_000251	Q13402	MYO7A_HUMAN	myosin VIIA isoform 1	1339	FERM 1.				actin filament-based movement|equilibrioception|lysosome organization|sensory perception of sound|visual perception	cytosol|lysosomal membrane|myosin complex|photoreceptor inner segment|photoreceptor outer segment|synapse	actin binding|ATP binding|calmodulin binding|microfilament motor activity			ovary(3)|breast(1)	4						AGGAGCGCAACGCCCCCTGGA	0.662000											OREG0021258	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	32	39					0	0	1	0	0
PRDM10	56980	broad.mit.edu	37	11	129817185	129817185	+	Silent	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr11:129817185G>A	uc001qfm.2	-	5	607	c.375C>T	c.(373-375)ACC>ACT	p.T125T	PRDM10_uc001qfj.2_Silent_p.T39T|PRDM10_uc001qfk.2_Silent_p.T39T|PRDM10_uc001qfl.2_Silent_p.T39T|PRDM10_uc010sbx.1_Silent_p.T39T|PRDM10_uc001qfn.2_Silent_p.T125T|PRDM10_uc009zct.1_Silent_p.T157T	NM_020228	NP_064613	Q9NQV6	PRD10_HUMAN	PR domain containing 10 isoform 1	125					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			pancreas(1)	1	all_hematologic(175;0.0537)	Breast(109;0.000496)|Lung NSC(97;0.000693)|all_lung(97;0.00151)|Medulloblastoma(222;0.0425)|all_neural(223;0.0837)		OV - Ovarian serous cystadenocarcinoma(99;0.0174)|Lung(977;0.176)|LUSC - Lung squamous cell carcinoma(976;0.185)		TGCCTAGAGGGGTCTGCAGAG	0.547000													27	43					0	0	1	0	0
LRP1	4035	broad.mit.edu	37	12	57573720	57573720	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr12:57573720G>A	uc001snd.2	+	30	5588	c.5122G>A	c.(5122-5124)GTC>ATC	p.V1708I		NM_002332	NP_002323	Q07954	LRP1_HUMAN	low density lipoprotein-related protein 1	1708	Extracellular (Potential).|LDL-receptor class B 14.				aorta morphogenesis|apoptotic cell clearance|negative regulation of platelet-derived growth factor receptor-beta signaling pathway|negative regulation of smooth muscle cell migration|negative regulation of Wnt receptor signaling pathway|positive regulation of cholesterol efflux|regulation of actin cytoskeleton organization|regulation of phospholipase A2 activity	coated pit|integral to plasma membrane|nucleus	apolipoprotein E binding|calcium ion binding|lipoprotein transporter activity|protein complex binding|receptor activity			ovary(8)|lung(3)|breast(3)|large_intestine(2)|central_nervous_system(2)|skin(2)|pancreas(2)	22				BRCA - Breast invasive adenocarcinoma(357;0.0103)	Alteplase(DB00009)|Anistreplase(DB00029)|Antihemophilic Factor(DB00025)|Becaplermin(DB00102)|Coagulation Factor IX(DB00100)|Tenecteplase(DB00031)	CCATGGCCTTGTCGTCCACCC	0.622000													47	64					0	0	1	0	0
C12orf51	283450	broad.mit.edu	37	12	112668608	112668608	+	Silent	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr12:112668608G>A	uc009zwc.2	-	33	4971	c.4953C>T	c.(4951-4953)CCC>CCT	p.P1651P	C12orf51_uc001ttr.1_5'Flank	NM_001109662	NP_001103132			chromosome 12 open reading frame 51											ovary(1)|lung(1)	2						CACTGATGAAGGGACGCACAG	0.498000													5	8					0	0	1	0	0
MTMR6	9107	broad.mit.edu	37	13	25823587	25823587	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr13:25823587G>C	uc001uqf.3	-	14	1968	c.1649C>G	c.(1648-1650)ACC>AGC	p.T550S	MTMR6_uc001uqe.1_Intron	NM_004685	NP_004676	Q9Y217	MTMR6_HUMAN	myotubularin related protein 6	550						cytoplasm|nuclear envelope	calcium-activated potassium channel activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity			ovary(2)|skin(2)	4		Lung SC(185;0.0225)|Breast(139;0.0351)		all cancers(112;0.00927)|Epithelial(112;0.0474)|OV - Ovarian serous cystadenocarcinoma(117;0.164)		CAATTCCTTGGTGAGGATGCC	0.353000													23	30					0	0	1	0	0
IPO5	3843	broad.mit.edu	37	13	98652854	98652854	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr13:98652854G>A	uc001vnf.1	+	10	1128	c.1063G>A	c.(1063-1065)GTT>ATT	p.V355I	IPO5_uc001vne.2_Missense_Mutation_p.V373I|IPO5_uc010tik.1_Missense_Mutation_p.V230I|IPO5_uc010til.1_Missense_Mutation_p.V295I|IPO5_uc001vng.1_5'Flank	NM_002271	NP_002262	O00410	IPO5_HUMAN	importin 5	355	Ran-GTP binding (By similarity).				interspecies interaction between organisms|NLS-bearing substrate import into nucleus|ribosomal protein import into nucleus	cytoplasm|nuclear pore|nucleolus	GTPase inhibitor activity|protein transporter activity|Ran GTPase binding			ovary(1)|lung(1)|skin(1)	3						TGGAAAGCTCGTTCTGCCGAT	0.418000													29	26					0	0	1	0	0
FARP1	10160	broad.mit.edu	37	13	99037979	99037979	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr13:99037979A>C	uc001vnj.2	+	8	1006	c.670A>C	c.(670-672)ATG>CTG	p.M224L	FARP1_uc001vnh.2_Missense_Mutation_p.M224L	NM_005766	NP_005757	Q9Y4F1	FARP1_HUMAN	FERM, RhoGEF, and pleckstrin domain protein 1	224	FERM.				regulation of Rho protein signal transduction	cytoplasm|cytoskeleton|extrinsic to membrane	cytoskeletal protein binding|Rho guanyl-nucleotide exchange factor activity			breast(2)	2	all_neural(89;0.0982)|Medulloblastoma(90;0.163)|Lung SC(71;0.184)		BRCA - Breast invasive adenocarcinoma(86;0.233)			TCGGCTAGAGATGTATGGAAT	0.488000													35	60					0	0	1	0	0
RYR3	6263	broad.mit.edu	37	15	33961646	33961646	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr15:33961646T>C	uc001zhi.2	+	37	5781	c.5711T>C	c.(5710-5712)CTC>CCC	p.L1904P	RYR3_uc010bar.2_Missense_Mutation_p.L1904P	NM_001036	NP_001027	Q15413	RYR3_HUMAN	ryanodine receptor 3	1904	4 X approximate repeats.|Cytoplasmic (By similarity).				cellular calcium ion homeostasis	integral to membrane	calcium ion binding|receptor activity|ryanodine-sensitive calcium-release channel activity			ovary(5)|central_nervous_system(4)|lung(1)	10		all_lung(180;7.18e-09)		all cancers(64;8.95e-12)|GBM - Glioblastoma multiforme(186;0.00109)|BRCA - Breast invasive adenocarcinoma(123;0.0363)		GAGGACCTTCTCCTTCACTGT	0.463000													20	29					0	0	1	0	0
ACTC1	70	broad.mit.edu	37	15	35085735	35085735	+	Silent	SNP	G	A	A	rs149432225		TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr15:35085735G>A	uc001ziu.1	-	3	408	c.165C>T	c.(163-165)TAC>TAT	p.Y55Y	uc001zit.1_Intron	NM_005159	NP_005150	P68032	ACTC_HUMAN	cardiac muscle alpha actin 1 proprotein	55					apoptosis|cardiac muscle tissue morphogenesis|cardiac myofibril assembly|muscle filament sliding|skeletal muscle thin filament assembly	actomyosin, actin part|cytosol|I band	ATP binding|ATPase activity|myosin binding			upper_aerodigestive_tract(1)|ovary(1)	2		all_lung(180;2.3e-08)		all cancers(64;5.83e-19)|GBM - Glioblastoma multiforme(113;1.98e-07)|BRCA - Breast invasive adenocarcinoma(123;0.0244)		CATCACCTACGTAGGAGTCCT	0.473000													31	33					0	0	1	0	0
THBS1	7057	broad.mit.edu	37	15	39885784	39885784	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr15:39885784T>C	uc001zkh.2	+	19	3361	c.3182T>C	c.(3181-3183)CTT>CCT	p.L1061P	THBS1_uc010bbi.2_Missense_Mutation_p.L533P	NM_003246	NP_003237	P07996	TSP1_HUMAN	thrombospondin 1 precursor	1061	TSP C-terminal.				activation of MAPK activity|anti-apoptosis|apoptosis|cell adhesion|cell cycle arrest|cell migration|cellular response to heat|chronic inflammatory response|engulfment of apoptotic cell|immune response|induction of apoptosis|negative regulation of angiogenesis|negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of blood vessel endothelial cell migration|negative regulation of caspase activity|negative regulation of cGMP-mediated signaling|negative regulation of dendritic cell antigen processing and presentation|negative regulation of endothelial cell proliferation|negative regulation of fibrinolysis|negative regulation of fibroblast growth factor receptor signaling pathway|negative regulation of focal adhesion assembly|negative regulation of interleukin-12 production|negative regulation of nitric oxide mediated signal transduction|negative regulation of plasma membrane long-chain fatty acid transport|negative regulation of plasminogen activation|peptide cross-linking|platelet activation|platelet degranulation|positive regulation of angiogenesis|positive regulation of blood vessel endothelial cell migration|positive regulation of fibroblast migration|positive regulation of macrophage activation|positive regulation of macrophage chemotaxis|positive regulation of phosphorylation|positive regulation of protein kinase B signaling cascade|positive regulation of reactive oxygen species metabolic process|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor-beta1 production|positive regulation of translation|positive regulation of tumor necrosis factor biosynthetic process|response to calcium ion|response to drug|response to glucose stimulus|response to hypoxia|response to magnesium ion|response to progesterone stimulus|sprouting angiogenesis	external side of plasma membrane|extracellular matrix|fibrinogen complex|platelet alpha granule lumen	calcium ion binding|collagen V binding|eukaryotic cell surface binding|fibrinogen binding|fibroblast growth factor 2 binding|fibronectin binding|heparin binding|identical protein binding|integrin binding|laminin binding|low-density lipoprotein particle binding|phosphatidylserine binding|proteoglycan binding|structural molecule activity|transforming growth factor beta binding			ovary(3)|central_nervous_system(3)	6		all_cancers(109;1.35e-17)|all_epithelial(112;2.07e-15)|Lung NSC(122;4.44e-11)|all_lung(180;1.11e-09)|Melanoma(134;0.0574)|Colorectal(260;0.117)|Ovarian(310;0.223)		GBM - Glioblastoma multiforme(113;2.77e-06)|BRCA - Breast invasive adenocarcinoma(123;0.105)	Becaplermin(DB00102)	TACTCGGGCCTTTCTGTGAAA	0.582000													62	104					0	0	1	0	0
HMG20A	10363	broad.mit.edu	37	15	77759508	77759508	+	Silent	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr15:77759508C>A	uc002bcr.2	+	5	510	c.309C>A	c.(307-309)CCC>CCA	p.P103P	HMG20A_uc002bcs.2_Silent_p.P103P	NM_018200	NP_060670	Q9NP66	HM20A_HUMAN	high-mobility group 20A	103	HMG box.				chromatin modification	nucleus	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			upper_aerodigestive_tract(1)|ovary(1)|central_nervous_system(1)	3						GCAATGCACCCAAATCCCCCC	0.403000													21	38					1.22574e-08	1.28828e-08	1	1	0
C15orf42	90381	broad.mit.edu	37	15	90118913	90118913	+	Silent	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr15:90118913C>A	uc002boe.2	+	1	96	c.96C>A	c.(94-96)ACC>ACA	p.T32T		NM_152259	NP_689472	Q7Z2Z1	TICRR_HUMAN	leucine-rich repeat kinase 1	32					cell cycle|DNA repair|DNA replication|formation of translation preinitiation complex|G2/M transition checkpoint|mitotic cell cycle DNA replication checkpoint|regulation of DNA-dependent DNA replication initiation|response to ionizing radiation	nucleus	chromatin binding|protein binding			ovary(4)|central_nervous_system(2)|skin(1)	7	Lung NSC(78;0.0237)|all_lung(78;0.0478)		BRCA - Breast invasive adenocarcinoma(143;0.128)			GCCTCCTCACCTATCTGAGTT	0.478000													4	9					0.00909568	0.00909568	1	1	0
Unknown	0	broad.mit.edu	37	15	101098922	101098922	+	RNA	SNP	T	C	C	rs9920217	by1000genomes	TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr15:101098922T>C	uc002bwc.1	+	1		c.38T>C								Homo sapiens cDNA clone IMAGE:4822975.																		GGAATGCTCATCAACTTGAGG	0.607000													4	43					0	0	1	0	0
MLST8	64223	broad.mit.edu	37	16	2258565	2258565	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr16:2258565C>T	uc002coz.2	+	8	932	c.813C>T	c.(811-813)GGC>GGT	p.G271G	MLST8_uc002coy.2_Silent_p.G271G|MLST8_uc002cpa.2_Silent_p.G87G|MLST8_uc002cpb.2_Silent_p.G270G|MLST8_uc010uvx.1_Silent_p.G205G|MLST8_uc002cpc.2_Silent_p.G271G|MLST8_uc002cpd.2_Silent_p.G205G|MLST8_uc002cpe.2_Silent_p.G271G|MLST8_uc002cpg.2_Silent_p.G290G|MLST8_uc002cph.2_RNA|MLST8_uc002cpf.2_Silent_p.G271G	NM_022372	NP_071767	Q9BVC4	LST8_HUMAN	G protein beta subunit-like	271	WD 7.				insulin receptor signaling pathway|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of TOR signaling cascade|T cell costimulation	cytosol	protein binding				0						CCTCCCGCGGCTGGATGTGGG	0.677000													41	129					0	0	1	0	0
PPP4C	5531	broad.mit.edu	37	16	30094761	30094761	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr16:30094761G>A	uc002dwe.2	+	6	494	c.350G>A	c.(349-351)AGT>AAT	p.S117N	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|PPP4C_uc002dwf.2_Missense_Mutation_p.S117N|PPP4C_uc002dwg.2_RNA|PPP4C_uc002dwh.2_Missense_Mutation_p.S38N	NM_002720	NP_002711	P60510	PP4C_HUMAN	protein phosphatase 4, catalytic subunit	117					microtubule cytoskeleton organization|regulation of double-strand break repair via homologous recombination	centrosome|nucleus	metal ion binding|NF-kappaB-inducing kinase activity|protein binding|protein serine/threonine phosphatase activity			skin(1)	1						AACCATGAGAGTCGCCAGATC	0.592000													88	59					0	0	1	0	0
Unknown	0	broad.mit.edu	37	16	70256290	70256290	+	RNA	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr16:70256290T>C	uc002eyl.1	-	2		c.1272A>G								Homo sapiens cDNA FLJ46379 fis, clone THYMU2003803, moderately similar to Homo sapiens PI-3-kinase-related kinase SMG-1 (SMG1).																		TTTCTTTTGATCCTCCAGCAA	0.308000													3	10					0	0	1	0	0
MARVELD3	91862	broad.mit.edu	37	16	71663293	71663293	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr16:71663293T>A	uc002fat.2	+	2	554	c.491T>A	c.(490-492)CTG>CAG	p.L164Q	MARVELD3_uc002fas.1_Missense_Mutation_p.L164Q|MARVELD3_uc002fau.2_Missense_Mutation_p.L164Q|MARVELD3_uc010cge.2_Missense_Mutation_p.C110S	NM_052858	NP_443090	Q96A59	MALD3_HUMAN	MARVEL domain containing 3 isoform 2	164	Pro-rich.|Cytoplasmic (Potential).					integral to membrane				skin(1)	1		Ovarian(137;0.125)				GAGAGATATCTGCCCTCGACC	0.502000													5	100					0	0	1	0	0
ABR	29	broad.mit.edu	37	17	916353	916353	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr17:916353T>C	uc002fsd.2	-	17	1953	c.1843A>G	c.(1843-1845)ATG>GTG	p.M615V	ABR_uc002fse.2_Missense_Mutation_p.M569V|ABR_uc010vqf.1_Missense_Mutation_p.M66V|ABR_uc010vqg.1_Missense_Mutation_p.M397V|ABR_uc002fsg.2_Missense_Mutation_p.M578V|ABR_uc002fsh.1_Intron|ABR_uc002fsf.2_5'Flank	NM_021962	NP_068781	Q12979	ABR_HUMAN	active breakpoint cluster region-related	615					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity|protein binding|Rho guanyl-nucleotide exchange factor activity			upper_aerodigestive_tract(1)	1				UCEC - Uterine corpus endometrioid carcinoma (25;0.0228)		ACCCCGTTCATCTCAATCACG	0.632000													34	78					0	0	1	0	0
CTNS	1497	broad.mit.edu	37	17	3550808	3550808	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr17:3550808C>T	uc002fwb.2	+	4	725	c.132C>T	c.(130-132)CTC>CTT	p.L44L	CTNS_uc002fwa.2_Silent_p.L44L|CTNS_uc010ckj.2_Silent_p.L44L|CTNS_uc010vrv.1_Intron|CTNS_uc010vrw.1_Intron	NM_004937	NP_004928	O60931	CTNS_HUMAN	cystinosin isoform 2	44	Lumenal (Potential).				ATP metabolic process|brain development|cognition|glutathione metabolic process	integral to membrane|late endosome|lysosomal membrane	L-cystine transmembrane transporter activity				0				COAD - Colon adenocarcinoma(5;0.0829)	L-Cystine(DB00138)	ACGTCAGCCTCACCCTGCGGT	0.602000													13	69					0	0	1	0	0
GPR179	440435	broad.mit.edu	37	17	36486249	36486249	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr17:36486249A>C	uc002hpz.2	-	11	3224	c.3203T>G	c.(3202-3204)ATC>AGC	p.I1068S		NM_001004334	NP_001004334	Q6PRD1	GP179_HUMAN	GPR158-like 1 precursor	1068	Cytoplasmic (Potential).					integral to membrane|plasma membrane	G-protein coupled receptor activity			ovary(3)	3	Breast(7;2.97e-12)	Breast(25;0.0101)|Ovarian(249;0.15)				TTTAGGGAAGATCTTGGGCCT	0.562000													26	72					0	0	1	0	0
MYO5B	4645	broad.mit.edu	37	18	47369741	47369741	+	Missense_Mutation	SNP	G	A	A	rs139632666	by1000genomes	TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr18:47369741G>A	uc002leb.2	-	34	4769	c.4481C>T	c.(4480-4482)TCG>TTG	p.S1494L	MYO5B_uc002ldz.2_Missense_Mutation_p.S64L|MYO5B_uc002lea.2_Missense_Mutation_p.S609L	NM_001080467	NP_001073936	Q9ULV0	MYO5B_HUMAN	myosin VB	1494					protein transport	myosin complex	actin binding|ATP binding|calmodulin binding|motor activity			ovary(2)|skin(2)|central_nervous_system(1)	5				READ - Rectum adenocarcinoma(32;0.103)		CACTGTGCCCGACAGCATCTG	0.557000													5	67					0	0	1	0	0
IL29	282618	broad.mit.edu	37	19	39787490	39787490	+	Missense_Mutation	SNP	T	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr19:39787490T>G	uc002okv.2	+	2	314	c.217T>G	c.(217-219)TTC>GTC	p.F73V		NM_172140	NP_742152	Q8IU54	IL29_HUMAN	interleukin 29 precursor	73					defense response to virus|negative regulation of cell proliferation|negative regulation of interleukin-13 production|negative regulation of interleukin-5 production|negative regulation of memory T cell differentiation|negative regulation of transcription, DNA-dependent|negative regulation of type 2 immune response|positive regulation of immune response|positive regulation of interferon-gamma production|positive regulation of MHC class I biosynthetic process|positive regulation of transcription, DNA-dependent|positive regulation of tyrosine phosphorylation of STAT protein	extracellular space|interleukin-28 receptor complex	cytokine activity|interleukin-28 receptor binding				0	all_cancers(60;1.85e-07)|all_lung(34;4.03e-08)|Lung NSC(34;4.66e-08)|all_epithelial(25;6.4e-07)|Ovarian(47;0.0512)		Epithelial(26;1.96e-27)|all cancers(26;2.05e-24)|Lung(45;0.000278)|LUSC - Lung squamous cell carcinoma(53;0.000335)			CTCTCCTGTCTTCCCCGGGAA	0.572000													18	24					0	0	1	0	0
PRR19	284338	broad.mit.edu	37	19	42814766	42814766	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr19:42814766C>T	uc002oti.2	+	3	1323	c.945C>T	c.(943-945)CCC>CCT	p.P315P	PRR19_uc002oth.1_3'UTR|PRR19_uc002otj.2_Silent_p.P315P|TMEM145_uc002otk.1_5'Flank	NM_199285	NP_954979	A6NJB7	PRR19_HUMAN	proline rich 19	315	Pro-rich.										0		Prostate(69;0.00682)				CTTCATCACCCCTGTTGCCCC	0.652000													71	113					0	0	1	0	0
RSPH6A	81492	broad.mit.edu	37	19	46317875	46317875	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr19:46317875G>C	uc002pdm.2	-	1	703	c.560C>G	c.(559-561)GCC>GGC	p.A187G		NM_030785	NP_110412	Q9H0K4	RSH6A_HUMAN	radial spokehead-like 1	187						intracellular				ovary(1)|central_nervous_system(1)	2						AGGCACCTGGGCACTGTAGTG	0.612000													23	38					0	0	1	0	0
PEG3	5178	broad.mit.edu	37	19	57325186	57325186	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr19:57325186A>G	uc002qnu.2	-	7	4975	c.4624T>C	c.(4624-4626)TGC>CGC	p.C1542R	ZIM2_uc010ygq.1_Intron|ZIM2_uc010ygr.1_Intron|ZIM2_uc002qnr.2_Intron|ZIM2_uc002qnq.2_Intron|ZIM2_uc010etp.2_Intron|ZIM2_uc010ygs.1_Intron|PEG3_uc002qnt.2_Missense_Mutation_p.C1513R|PEG3_uc002qnv.2_Missense_Mutation_p.C1542R|PEG3_uc002qnw.2_Missense_Mutation_p.C1418R|PEG3_uc002qnx.2_Missense_Mutation_p.C1416R|PEG3_uc010etr.2_Missense_Mutation_p.C1542R	NM_001146186	NP_001139658	Q9GZU2	PEG3_HUMAN	paternally expressed 3 isoform 1	1542					apoptosis|viral reproduction	cytoplasm|nucleus	nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(7)|skin(2)|upper_aerodigestive_tract(1)|large_intestine(1)|pancreas(1)	12		Colorectal(82;0.000256)|all_neural(62;0.103)|Ovarian(87;0.243)		GBM - Glioblastoma multiforme(193;0.0269)		TAGCCTGAGCACTCCCCAAAG	0.488000													28	73					0	0	1	0	0
ASAP2	8853	broad.mit.edu	37	2	9528579	9528579	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr2:9528579T>C	uc002qzh.2	+	22	2627	c.2287T>C	c.(2287-2289)TAC>CAC	p.Y763H	ASAP2_uc002qzi.2_Missense_Mutation_p.Y763H	NM_003887	NP_003878	O43150	ASAP2_HUMAN	ArfGAP with SH3 domain, ankyrin repeat and PH	763					regulation of ARF GTPase activity	Golgi cisterna membrane|plasma membrane	ARF GTPase activator activity|protein binding|zinc ion binding				0						GAATGAGACTTACGGAGCCCT	0.597000													18	25					0	0	1	0	0
SLC4A1AP	22950	broad.mit.edu	37	2	27888159	27888159	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr2:27888159A>G	uc002rlk.3	+	2	1300	c.1018A>G	c.(1018-1020)ATG>GTG	p.M340V	SUPT7L_uc002rlh.1_5'Flank|SUPT7L_uc002rli.1_5'Flank|SUPT7L_uc010ymf.1_5'Flank|SUPT7L_uc002rlj.1_5'Flank|SUPT7L_uc010ezh.1_5'Flank	NM_018158	NP_060628	Q9BWU0	NADAP_HUMAN	solute carrier family 4 (anion exchanger),	340						cytoplasm|nucleus	double-stranded RNA binding|protein binding				0	Acute lymphoblastic leukemia(172;0.155)					CACCTGGGGAATGGGTAAGAA	0.383000													49	55					0	0	1	0	0
GPR75	10936	broad.mit.edu	37	2	54080607	54080607	+	Silent	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr2:54080607A>G	uc002rxo.3	-	2	1558	c.1287T>C	c.(1285-1287)TCT>TCC	p.S429S	ASB3_uc002rxi.3_Intron	NM_006794	NP_006785	O95800	GPR75_HUMAN	G protein-coupled receptor 75	429	Cytoplasmic (Potential).					integral to plasma membrane	G-protein coupled receptor activity			ovary(1)|skin(1)	2			Lung(47;0.125)|LUSC - Lung squamous cell carcinoma(58;0.181)			ACATGTAGGCAGAGTTTGTTT	0.448000													46	131					0	0	1	0	0
USP39	10713	broad.mit.edu	37	2	85875075	85875075	+	Nonsense_Mutation	SNP	T	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr2:85875075T>G	uc002sqe.2	+	12	1622	c.1586T>G	c.(1585-1587)TTA>TGA	p.L529*	USP39_uc002sqb.2_Nonsense_Mutation_p.L260*|USP39_uc010ysu.1_Nonsense_Mutation_p.L451*|USP39_uc010ysv.1_Nonsense_Mutation_p.L426*|USP39_uc002sqf.2_Intron|USP39_uc002sqg.2_Nonsense_Mutation_p.L529*|USP39_uc010fgo.2_Missense_Mutation_p.Y484D	NM_006590	NP_006581	Q53GS9	SNUT2_HUMAN	ubiquitin specific protease 39	529					spliceosome assembly|ubiquitin-dependent protein catabolic process	nucleus	protein binding|ubiquitin thiolesterase activity|zinc ion binding			ovary(1)	1						TGGTATGAATTACAAGACCTC	0.478000													36	47					0	0	1	0	0
MBD5	55777	broad.mit.edu	37	2	149248040	149248040	+	Silent	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr2:149248040A>C	uc002twm.3	+	12	5128	c.4140A>C	c.(4138-4140)CCA>CCC	p.P1380P	MBD5_uc010zbs.1_Intron|MBD5_uc010fns.2_Silent_p.P1380P|MBD5_uc002two.2_Silent_p.P638P|MBD5_uc002twp.2_Silent_p.P430P	NM_018328	NP_060798	Q9P267	MBD5_HUMAN	methyl-CpG binding domain protein 5	1380						chromosome|nucleus	chromatin binding|DNA binding			skin(3)|ovary(2)	5				BRCA - Breast invasive adenocarcinoma(221;0.0569)		ATTATAGACCAAGGACGTTCA	0.453000													45	55					0	0	1	0	0
PAX3	5077	broad.mit.edu	37	2	223066673	223066673	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr2:223066673C>T	uc010fwo.2	-	8	1776	c.1410G>A	c.(1408-1410)CAG>CAA	p.Q470Q	PAX3_uc002vmt.1_Silent_p.Q470Q|PAX3_uc002vmy.1_Silent_p.Q469Q|PAX3_uc002vmv.1_Silent_p.Q470Q|PAX3_uc002vmw.1_Intron|PAX3_uc002vmx.1_Intron	NM_181457	NP_852122	P23760	PAX3_HUMAN	paired box 3 isoform PAX3	470					apoptosis|organ morphogenesis|positive regulation of transcription from RNA polymerase II promoter|sensory perception of sound|transcription from RNA polymerase II promoter	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity		PAX3/FOXO1(749)|PAX3/NCOA1(8)|PAX3/NCOA2(4)	soft_tissue(761)|ovary(4)|skin(1)	766		Renal(207;0.0183)		Epithelial(121;4.13e-10)|all cancers(144;1.85e-07)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		TTTGTCCATACTGCCCATATT	0.468000			T	FOXO1A|NCOA1	alveolar rhabdomyosarcoma		Waardenburg syndrome; craniofacial-deafness-hand syndrome						6	66					0	0	1	0	0
SAMHD1	25939	broad.mit.edu	37	20	35532631	35532631	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr20:35532631T>C	uc002xgh.1	-	13	1562	c.1432A>G	c.(1432-1434)AAA>GAA	p.K478E	SAMHD1_uc010gft.1_RNA	NM_015474	NP_056289	Q9Y3Z3	SAMH1_HUMAN	SAM domain- and HD domain-containing protein 1	478					defense response to virus|innate immune response|regulation of innate immune response	nucleus	metal ion binding|phosphoric diester hydrolase activity				0		Myeloproliferative disorder(115;0.00878)				GCAACCTCTTTTGGAAGAGAT	0.388000													101	72					0	0	1	0	0
POM121L9P	29774	broad.mit.edu	37	22	24659515	24659515	+	RNA	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr22:24659515G>A	uc002zzs.3	+	7		c.3247G>A			uc011ajp.1_5'Flank	NR_003714				Homo sapiens mRNA; cDNA DKFZp434P211 (from clone DKFZp434P211).												0						CTGGGCCATGGAGCACTCTGA	0.478000													7	11					0	0	1	0	0
CELSR3	1951	broad.mit.edu	37	3	48690562	48690562	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr3:48690562A>C	uc003cul.2	-	10	5788	c.5507T>G	c.(5506-5508)CTC>CGC	p.L1836R	CELSR3_uc003cuf.1_Missense_Mutation_p.L1906R|CELSR3_uc010hkg.2_5'Flank	NM_001407	NP_001398	Q9NYQ7	CELR3_HUMAN	cadherin EGF LAG seven-pass G-type receptor 3	1836	Extracellular (Potential).|Laminin G-like 2.				homophilic cell adhesion|multicellular organismal development|neuropeptide signaling pathway	integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein binding			ovary(5)|upper_aerodigestive_tract(2)|central_nervous_system(2)|skin(2)	11				BRCA - Breast invasive adenocarcinoma(193;0.000292)|KIRC - Kidney renal clear cell carcinoma(197;0.00549)|Kidney(197;0.00619)		GTCCAGAAGGAGATGGGAAGC	0.622000													25	32					0	0	1	0	0
COL6A6	131873	broad.mit.edu	37	3	130292932	130292932	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr3:130292932T>A	uc010htl.2	+	7	3141	c.3110T>A	c.(3109-3111)GTG>GAG	p.V1037E		NM_001102608	NP_001096078	A6NMZ7	CO6A6_HUMAN	collagen type VI alpha 6 precursor	1037	Nonhelical region.|VWFA 6.				axon guidance|cell adhesion	collagen				ovary(6)|central_nervous_system(1)|pancreas(1)	8						CTCAACAGAGTGCGAATAGGA	0.418000													18	19					0	0	1	0	0
MUC4	4585	broad.mit.edu	37	3	195505836	195505836	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr3:195505836G>C	uc011bto.1	-	3	12691	c.12231C>G	c.(12229-12231)CAC>CAG	p.H4077Q	MUC4_uc003fva.2_5'Flank|MUC4_uc003fvb.2_5'Flank|MUC4_uc003fvc.2_5'Flank|MUC4_uc003fvd.2_5'Flank|MUC4_uc003fve.2_5'Flank|MUC4_uc010hzr.2_5'Flank|MUC4_uc011btf.1_Intron|MUC4_uc011btg.1_Intron|MUC4_uc011bth.1_Intron|MUC4_uc011bti.1_Intron|MUC4_uc011btj.1_Intron|MUC4_uc011btk.1_Intron|MUC4_uc011btl.1_Intron|MUC4_uc011btm.1_Intron|MUC4_uc011btn.1_Intron|MUC4_uc003fvo.2_Intron|MUC4_uc003fvp.2_Intron|MUC4_uc010hzu.1_Intron	NM_018406	NP_060876	Q99102	MUC4_HUMAN	mucin 4 isoform a	Error:AA_residue_mismatch_between_GAF_and_UniProt_prot_seqs_after_alignment					cell-matrix adhesion	integral to plasma membrane|proteinaceous extracellular matrix	ErbB-2 class receptor binding|extracellular matrix constituent, lubricant activity				0	all_cancers(143;1.11e-08)|Ovarian(172;0.0634)|Breast(254;0.206)	Lung NSC(153;0.191)	Epithelial(36;3.72e-24)|all cancers(36;6.22e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.1e-18)|Lung(62;4.65e-05)|LUSC - Lung squamous cell carcinoma(58;5.31e-05)	GBM - Glioblastoma multiforme(46;2.37e-05)		GAGGGGTGGCGTGACCTGTGG	0.597000													2	5					0	0	1	0	0
LRPAP1	4043	broad.mit.edu	37	4	3519768	3519768	+	Silent	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:3519768A>G	uc003ghi.2	-	5	829	c.744T>C	c.(742-744)ACT>ACC	p.T248T		NM_002337	NP_002328	P30533	AMRP_HUMAN	low density lipoprotein receptor-related protein	248	LDL receptor binding (Potential).|Potential.				negative regulation of protein binding|negative regulation of very-low-density lipoprotein particle clearance|protein folding|vesicle-mediated transport	cell surface|integral to membrane|plasma membrane	asialoglycoprotein receptor activity|heparin binding|low-density lipoprotein particle receptor binding|receptor antagonist activity|unfolded protein binding|very-low-density lipoprotein particle receptor binding			ovary(1)|skin(1)	2				UCEC - Uterine corpus endometrioid carcinoma (64;0.165)		CACCAGCCTCAGTGCTGTAGC	0.657000													10	27					0	0	1	0	0
TBC1D19	55296	broad.mit.edu	37	4	26737100	26737100	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:26737100T>A	uc003gsf.3	+	16	1378	c.1108T>A	c.(1108-1110)TCA>ACA	p.S370T	TBC1D19_uc010iew.2_Missense_Mutation_p.S370T|TBC1D19_uc011bxu.1_Missense_Mutation_p.S305T	NM_018317	NP_060787	Q8N5T2	TBC19_HUMAN	TBC1 domain family, member 19	370	Rab-GAP TBC.					intracellular	Rab GTPase activator activity			breast(1)	1		Breast(46;0.0503)				TCATGGATTTTCAATGTATGG	0.264000													4	11					0	0	1	0	0
UGT2B10	7365	broad.mit.edu	37	4	69870721	69870721	+	Silent	SNP	A	G	G	rs111542944		TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:69870721A>G	uc011cao.1	-	9	1465	c.1329T>C	c.(1327-1329)CAT>CAC	p.H443H	UGT2B10_uc011can.1_Silent_p.H359H			P36537	UDB10_HUMAN	RecName: Full=UDP-glucuronosyltransferase 2B28;          Short=UDPGT 2B28;          EC=2.4.1.17; Flags: Precursor;	480					lipid metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	glucuronosyltransferase activity			skin(3)|ovary(2)	5						AGGTGAGGTCATGGGCTGCAA	0.478000													6	161					0	0	1	0	0
AFF1	4299	broad.mit.edu	37	4	88029381	88029381	+	Missense_Mutation	SNP	G	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:88029381G>T	uc003hqj.3	+	10	1833	c.1426G>T	c.(1426-1428)GAC>TAC	p.D476Y	AFF1_uc011ccz.1_Missense_Mutation_p.D483Y|AFF1_uc003hqk.3_Missense_Mutation_p.D476Y|AFF1_uc011cda.1_Missense_Mutation_p.D114Y	NM_005935	NP_005926	P51825	AFF1_HUMAN	myeloid/lymphoid or mixed-lineage leukemia	476						nucleus	sequence-specific DNA binding transcription factor activity			breast(1)	1		Acute lymphoblastic leukemia(40;0.0935)|all_hematologic(202;0.111)|Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.000233)		AAGCACCAGTGACTCAGACAG	0.512000													20	36					3.8784e-16	4.29544e-16	1	1	0
SEC24B	10427	broad.mit.edu	37	4	110415933	110415933	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:110415933A>G	uc003hzk.2	+	6	1464	c.1409A>G	c.(1408-1410)TAT>TGT	p.Y470C	SEC24B_uc003hzl.2_Missense_Mutation_p.Y435C|SEC24B_uc011cfp.1_Missense_Mutation_p.Y501C|SEC24B_uc011cfq.1_Missense_Mutation_p.Y470C|SEC24B_uc011cfr.1_Missense_Mutation_p.Y435C	NM_006323	NP_006314	O95487	SC24B_HUMAN	SEC24 (S. cerevisiae) homolog B isoform a	470					COPII vesicle coating|intracellular protein transport|post-translational protein modification|protein N-linked glycosylation via asparagine	COPII vesicle coat|cytosol|endoplasmic reticulum membrane|Golgi membrane|perinuclear region of cytoplasm	protein binding|transporter activity|zinc ion binding			ovary(2)|large_intestine(1)	3		Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;3.03e-05)		CAGCCTGGTTATCAGAATGCT	0.473000													55	75					0	0	1	0	0
SPATA5	166378	broad.mit.edu	37	4	123848831	123848831	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:123848831A>G	uc003iez.3	+	2	279	c.206A>G	c.(205-207)CAT>CGT	p.H69R	SPATA5_uc003iey.2_Missense_Mutation_p.H68R	NM_145207	NP_660208	Q8NB90	SPAT5_HUMAN	spermatogenesis associated 5	69					cell differentiation|multicellular organismal development|spermatogenesis	mitochondrion	ATP binding|nucleoside-triphosphatase activity				0						TCCCTTATTCATCTTGGACTC	0.338000													51	58					0	0	1	0	0
TRIM2	23321	broad.mit.edu	37	4	154215496	154215496	+	Missense_Mutation	SNP	A	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:154215496A>T	uc003ing.2	+	5	765	c.564A>T	c.(562-564)GAA>GAT	p.E188D	TRIM2_uc003inh.2_Missense_Mutation_p.E215D	NM_001130067	NP_001123539	Q9C040	TRIM2_HUMAN	tripartite motif-containing 2 isoform 2	188						cytoplasm	zinc ion binding			central_nervous_system(1)	1	all_hematologic(180;0.093)	Medulloblastoma(177;0.00225)		GBM - Glioblastoma multiforme(119;0.0102)|LUSC - Lung squamous cell carcinoma(193;0.0703)		TCATCTCTGAAATCATTCATC	0.413000													29	42					0	0	1	0	0
DCHS2	54798	broad.mit.edu	37	4	155225827	155225827	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:155225827T>C	uc003inw.2	-	17	4234	c.4234A>G	c.(4234-4236)ATA>GTA	p.I1412V		NM_017639	NP_060109	Q6V1P9	PCD23_HUMAN	dachsous 2 isoform 1	1412	Cadherin 12.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(3)|pancreas(1)	4	all_hematologic(180;0.208)	Renal(120;0.0854)		LUSC - Lung squamous cell carcinoma(193;0.107)		TTACCAATTATGTGATATTCA	0.219000													23	23					0	0	1	0	0
LOC285501	285501	broad.mit.edu	37	4	178897009	178897009	+	RNA	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:178897009C>T	uc010iru.2	+	5		c.678C>T				NR_028342				Homo sapiens cDNA clone IMAGE:4828874.												0		all_lung(41;6.03e-08)|Lung NSC(41;4.26e-07)|Breast(14;0.00066)|Melanoma(52;0.00168)|Prostate(90;0.0129)|all_hematologic(60;0.0202)|Renal(120;0.0246)|Colorectal(36;0.0508)|Hepatocellular(41;0.236)		all cancers(43;9.24e-25)|Epithelial(43;6.28e-22)|OV - Ovarian serous cystadenocarcinoma(60;5.29e-10)|LUSC - Lung squamous cell carcinoma(1;2.61e-05)|Lung(1;3.22e-05)|GBM - Glioblastoma multiforme(59;0.000185)|Colorectal(24;0.000244)|STAD - Stomach adenocarcinoma(60;0.000777)|COAD - Colon adenocarcinoma(29;0.000884)		CACTGGGGCACGGGAAAGGGG	0.408000													5	117					0	0	1	0	0
FAT1	2195	broad.mit.edu	37	4	187539116	187539116	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr4:187539116A>G	uc003izf.2	-	10	8812	c.8624T>C	c.(8623-8625)CTT>CCT	p.L2875P		NM_005245	NP_005236	Q14517	FAT1_HUMAN	FAT tumor suppressor 1 precursor	2875	Extracellular (Potential).|Cadherin 26.				actin filament organization|anatomical structure morphogenesis|cell migration|cell-cell signaling|establishment or maintenance of cell polarity|homophilic cell adhesion	cell-cell junction|integral to plasma membrane|nucleus|perinuclear region of cytoplasm	calcium ion binding|protein binding			ovary(10)|central_nervous_system(1)|pancreas(1)	12						TTCATGGTCAAGTTCCTTTAA	0.418000										HNSCC(5;0.00058)			24	37					0	0	1	0	0
SLC6A19	340024	broad.mit.edu	37	5	1219640	1219640	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:1219640T>C	uc003jbw.3	+	10	1455	c.1399T>C	c.(1399-1401)TTC>CTC	p.F467L		NM_001003841	NP_001003841	Q695T7	S6A19_HUMAN	solute carrier family 6, member 19	467	Helical; Name=9; (Potential).				cellular nitrogen compound metabolic process	integral to plasma membrane	amino acid transmembrane transporter activity|neurotransmitter:sodium symporter activity				0	all_cancers(3;3.55e-15)|Lung NSC(6;2.89e-14)|all_lung(6;2.2e-13)|all_epithelial(6;3.75e-10)		Epithelial(17;0.000356)|all cancers(22;0.00137)|OV - Ovarian serous cystadenocarcinoma(19;0.00239)|Lung(60;0.185)			CCTGGGGACATTCCTCATTGG	0.627000													20	27					0	0	1	0	0
TRIO	7204	broad.mit.edu	37	5	14497016	14497016	+	Missense_Mutation	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:14497016C>A	uc003jff.2	+	50	7915	c.7909C>A	c.(7909-7911)CGT>AGT	p.R2637S	TRIO_uc003jfg.2_RNA	NM_007118	NP_009049	O75962	TRIO_HUMAN	triple functional domain (PTPRF interacting)	2637					apoptosis|axon guidance|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|transmembrane receptor protein tyrosine phosphatase signaling pathway	cytosol	ATP binding|protein serine/threonine kinase activity|Rho guanyl-nucleotide exchange factor activity			skin(4)|central_nervous_system(3)|ovary(3)|large_intestine(2)|stomach(2)|breast(2)|upper_aerodigestive_tract(1)|kidney(1)	18	Lung NSC(4;0.000742)					CACAGCACTCCGTTTAAGGAA	0.448000													29	39					5.60225e-13	6.01075e-13	1	1	0
POLK	51426	broad.mit.edu	37	5	74892358	74892358	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:74892358G>C	uc003kdw.2	+	13	1936	c.1840G>C	c.(1840-1842)GAG>CAG	p.E614Q	POLK_uc003kdx.2_RNA|POLK_uc003kdy.2_RNA|POLK_uc010izq.2_Missense_Mutation_p.E416Q|POLK_uc003kec.2_Missense_Mutation_p.E524Q|POLK_uc010izr.2_RNA|POLK_uc010izs.2_RNA|POLK_uc003ked.2_Intron|POLK_uc003kee.2_Intron|POLK_uc003kef.2_Missense_Mutation_p.E524Q	NM_016218	NP_057302	Q9UBT6	POLK_HUMAN	DNA-directed DNA polymerase kappa	614					DNA replication|nucleotide-excision repair, DNA gap filling	nucleus	damaged DNA binding|DNA-directed DNA polymerase activity|metal ion binding			ovary(2)|kidney(2)	4		all_lung(232;0.0131)|Lung NSC(167;0.0282)|Ovarian(174;0.0798)|Prostate(461;0.184)		OV - Ovarian serous cystadenocarcinoma(47;2.9e-54)|all cancers(79;1.27e-42)		GGAAATATCAGAGAATTCAGA	0.368000								DNA_polymerases_(catalytic_subunits)|Direct_reversal_of_damage					69	81					0	0	1	0	0
BHMT	635	broad.mit.edu	37	5	78426847	78426847	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:78426847A>G	uc003kfu.3	+	8	1234	c.1129A>G	c.(1129-1131)AAA>GAA	p.K377E	BHMT_uc011cti.1_Missense_Mutation_p.K224E	NM_001713	NP_001704	Q93088	BHMT1_HUMAN	betaine-homocysteine methyltransferase	377					protein methylation|regulation of homocysteine metabolic process	cytoplasm	betaine-homocysteine S-methyltransferase activity|homocysteine S-methyltransferase activity|zinc ion binding			ovary(1)	1		all_lung(232;0.00051)|Lung NSC(167;0.00131)|Ovarian(174;0.0261)|Prostate(461;0.191)		OV - Ovarian serous cystadenocarcinoma(54;1.88e-45)|Epithelial(54;8.07e-41)|all cancers(79;3.51e-36)	L-Methionine(DB00134)	GGGAGTGACCAAAGGAACAGC	0.493000													50	101					0	0	1	0	0
MSH3	4437	broad.mit.edu	37	5	80040402	80040402	+	Silent	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:80040402G>A	uc003kgz.2	+	12	1984	c.1731G>A	c.(1729-1731)AAG>AAA	p.K577K		NM_002439	NP_002430	P20585	MSH3_HUMAN	mutS homolog 3	577					maintenance of DNA repeat elements|meiotic mismatch repair|negative regulation of DNA recombination|positive regulation of helicase activity|reciprocal meiotic recombination|somatic recombination of immunoglobulin gene segments	MutSbeta complex|nuclear chromosome	ATP binding|DNA-dependent ATPase activity|double-strand/single-strand DNA junction binding|enzyme binding|loop DNA binding|Y-form DNA binding	p.K577T(1)		lung(2)|ovary(1)|breast(1)	4		Lung NSC(167;0.00479)|all_lung(232;0.00507)|Ovarian(174;0.0261)|Breast(144;0.244)		OV - Ovarian serous cystadenocarcinoma(54;2.38e-45)|Epithelial(54;1.58e-38)|all cancers(79;4.93e-33)		GGAAGTTAAAGAAGTGGGTGA	0.338000								MMR					20	28					0	0	1	0	0
SOX30	11063	broad.mit.edu	37	5	157075894	157075894	+	Missense_Mutation	SNP	A	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:157075894A>T	uc003lxb.1	-	2	1320	c.978T>A	c.(976-978)GAT>GAA	p.D326E	SOX30_uc003lxc.1_Missense_Mutation_p.D326E|SOX30_uc011dds.1_Missense_Mutation_p.D21E	NM_178424	NP_848511	O94993	SOX30_HUMAN	SRY (sex determining region Y)-box 30 isoform a	326					regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-dependent|response to corticosteroid stimulus|transcription, DNA-dependent	nucleus|nucleus	sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity			ovary(1)|central_nervous_system(1)	2	Renal(175;0.00488)	Medulloblastoma(196;0.0354)|all_neural(177;0.138)	Kidney(164;0.000171)|KIRC - Kidney renal clear cell carcinoma(164;0.000785)			TGAAGGGAGTATCTGGTATGC	0.428000													34	55					0	0	1	0	0
NHP2	55651	broad.mit.edu	37	5	177580732	177580732	+	Silent	SNP	G	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:177580732G>T	uc003mir.2	-	1	230	c.87C>A	c.(85-87)GTC>GTA	p.V29V	NHP2_uc003mis.2_Silent_p.V29V	NM_017838	NP_060308	Q9NX24	NHP2_HUMAN	nucleolar protein family A, member 2 isoform a	29					rRNA pseudouridine synthesis	Cajal body|nucleolus|small nucleolar ribonucleoprotein complex	protein binding|snoRNA binding				0						GGTTCTGGTTGACCAGCAGCT	0.662000													20	18					8.28177e-16	9.07471e-16	1	1	0
MAML1	9794	broad.mit.edu	37	5	179193185	179193185	+	Nonsense_Mutation	SNP	G	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:179193185G>T	uc003mkm.2	+	2	1437	c.1174G>T	c.(1174-1176)GAG>TAG	p.E392*	MAML1_uc003mkn.1_Nonsense_Mutation_p.E392*	NM_014757	NP_055572	Q92585	MAML1_HUMAN	mastermind-like 1	392					Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear speck	peptide antigen binding|protein kinase binding|transcription coactivator activity			lung(4)|ovary(2)	6	all_cancers(89;0.000197)|all_epithelial(37;6.7e-05)|Renal(175;0.000159)|Lung NSC(126;0.00121)|all_lung(126;0.00218)	all_cancers(40;0.0308)|Medulloblastoma(196;0.00498)|all_neural(177;0.0138)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			AGGGGCCTCAGAGCTGTCCTC	0.657000													23	68					2.32416e-17	2.60205e-17	1	1	0
TBC1D9B	23061	broad.mit.edu	37	5	179320371	179320371	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:179320371T>A	uc003mlh.2	-	5	711	c.674A>T	c.(673-675)GAG>GTG	p.E225V	TBC1D9B_uc003mli.2_Missense_Mutation_p.E225V|TBC1D9B_uc003mlj.2_Missense_Mutation_p.E225V	NM_198868	NP_942568	Q66K14	TBC9B_HUMAN	TBC1 domain family, member 9B (with GRAM domain)	225						integral to membrane|intracellular	calcium ion binding|Rab GTPase activator activity			breast(1)|skin(1)	2	all_cancers(89;0.000197)|all_epithelial(37;6.84e-05)|Renal(175;0.000159)|Lung NSC(126;0.00136)|all_lung(126;0.00243)	all_cancers(40;0.0236)|Medulloblastoma(196;0.00498)|all_neural(177;0.0138)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			GAAGAAGAGCTCCTGGTCGCG	0.607000													23	36					0	0	1	0	0
TBC1D7	51256	broad.mit.edu	37	6	13307966	13307966	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr6:13307966A>C	uc003naj.2	-	6	622	c.531T>G	c.(529-531)TTT>TTG	p.F177L	TBC1D7_uc011dis.1_Intron|TBC1D7_uc003nan.2_Missense_Mutation_p.F177L|TBC1D7_uc003nal.2_Missense_Mutation_p.F177L|TBC1D7_uc003nam.2_Missense_Mutation_p.F177L|TBC1D7_uc003nao.2_Missense_Mutation_p.F150L|TBC1D7_uc010jpd.2_Missense_Mutation_p.F131L|TBC1D7_uc003nap.2_Missense_Mutation_p.F150L	NM_016495	NP_057579	Q9P0N9	TBCD7_HUMAN	TBC1 domain family, member 7 isoform a	177	Rab-GAP TBC.				positive regulation of protein ubiquitination	cytoplasmic membrane-bounded vesicle	protein binding|Rab GTPase activator activity			ovary(1)	1	Breast(50;0.0296)|Ovarian(93;0.0339)	all_hematologic(90;0.135)	Epithelial(50;0.0784)|BRCA - Breast invasive adenocarcinoma(129;0.13)|all cancers(50;0.21)			AGTATTGTTCAAACGCTTTTG	0.398000													21	52					0	0	1	0	0
AHI1	54806	broad.mit.edu	37	6	135644423	135644423	+	Nonsense_Mutation	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr6:135644423C>A	uc003qgi.2	-	25	3589	c.3205G>T	c.(3205-3207)GAA>TAA	p.E1069*	AHI1_uc003qgf.2_RNA|AHI1_uc003qgg.2_Nonsense_Mutation_p.E519*|AHI1_uc003qgh.2_Nonsense_Mutation_p.E1069*|AHI1_uc003qgj.2_Nonsense_Mutation_p.E1069*|AHI1_uc003qgk.3_Intron	NM_001134831	NP_001128303	Q8N157	AHI1_HUMAN	Abelson helper integration site 1 isoform a	1069	SH3.					adherens junction|cilium|microtubule basal body				ovary(1)|kidney(1)|central_nervous_system(1)	3	Breast(56;0.239)|Colorectal(23;0.24)			GBM - Glioblastoma multiforme(68;0.00904)|OV - Ovarian serous cystadenocarcinoma(155;0.00991)		ATGGTTAGTTCATCTGATCGA	0.438000													12	14					0.00010058	0.000102572	1	1	0
REPS1	85021	broad.mit.edu	37	6	139251190	139251190	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr6:139251190G>C	uc003qii.2	-	9	1760	c.1181C>G	c.(1180-1182)GCT>GGT	p.A394G	REPS1_uc003qig.3_Missense_Mutation_p.A394G|REPS1_uc011edr.1_Missense_Mutation_p.A394G|REPS1_uc003qij.2_Missense_Mutation_p.A394G|REPS1_uc003qik.2_Missense_Mutation_p.A27G	NM_031922	NP_114128	Q96D71	REPS1_HUMAN	RALBP1 associated Eps domain containing 1	394						coated pit|plasma membrane	calcium ion binding|SH3 domain binding			lung(1)|breast(1)	2				GBM - Glioblastoma multiforme(68;0.000434)|OV - Ovarian serous cystadenocarcinoma(155;0.000548)		AGGAGCTTCAGCAGGAGAGCC	0.418000													45	51					0	0	1	0	0
HOXA3	3200	broad.mit.edu	37	7	27147884	27147884	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr7:27147884G>A	uc011jzl.1	-	3	1182	c.982C>T	c.(982-984)CGC>TGC	p.R328C	HOXA3_uc011jzk.1_Missense_Mutation_p.R170C|HOXA3_uc003syk.2_Missense_Mutation_p.R328C	NM_030661	NP_109377	O43365	HXA3_HUMAN	homeobox A3 isoform a	328					angiogenesis	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(2)	2						GCCGTGTAGCGCTTCTGTGGG	0.726000													5	11					0	0	1	0	0
ABCA13	154664	broad.mit.edu	37	7	48411809	48411809	+	Silent	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr7:48411809C>A	uc003toq.2	+	33	10873	c.10848C>A	c.(10846-10848)GCC>GCA	p.A3616A	ABCA13_uc010kys.1_Silent_p.A690A|ABCA13_uc003tos.1_Silent_p.A442A	NM_152701	NP_689914	Q86UQ4	ABCAD_HUMAN	ATP binding cassette, sub-family A (ABC1),	3616	Helical; (Potential).				transport	integral to membrane	ATP binding|ATPase activity			ovary(5)|central_nervous_system(4)|skin(1)	10						ATTTCCTGGCCTGGTTCCTGG	0.463000													29	47					4.59853e-10	4.88297e-10	1	1	0
TMEM139	135932	broad.mit.edu	37	7	142983611	142983611	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr7:142983611T>C	uc010lov.2	+	4	479	c.340T>C	c.(340-342)TAC>CAC	p.Y114H	CASP2_uc003wco.2_5'Flank|CASP2_uc003wcp.2_5'Flank|CASP2_uc011kta.1_5'Flank|TMEM139_uc003wck.3_Missense_Mutation_p.Y114H|TMEM139_uc003wcl.2_Missense_Mutation_p.Y114H|TMEM139_uc003wcm.2_Missense_Mutation_p.Y114H|TMEM139_uc003wcn.2_RNA	NM_153345	NP_699176	Q8IV31	TM139_HUMAN	transmembrane protein 139 precursor	114	Cytoplasmic (Potential).					integral to membrane					0	Melanoma(164;0.059)					ACCACCCCCCTACAGCACTGT	0.577000													41	88					0	0	1	0	0
CA8	767	broad.mit.edu	37	8	61192348	61192348	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr8:61192348C>T	uc003xtz.1	-	2	440	c.192G>A	c.(190-192)TCG>TCA	p.S64S	CA8_uc003xua.1_Silent_p.S64S|CA8_uc003xub.2_Silent_p.S64S	NM_004056	NP_004047	P35219	CAH8_HUMAN	carbonic anhydrase VIII	64					one-carbon metabolic process		carbonate dehydratase activity|zinc ion binding				0		all_cancers(86;0.172)|all_epithelial(80;0.0383)|all_lung(136;0.0413)|Lung NSC(129;0.0474)				CATCCAACAGCGAGGGGTCAT	0.473000													61	33					0	0	1	0	0
C9orf5	23731	broad.mit.edu	37	9	111853340	111853340	+	Nonsense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr9:111853340G>A	uc004bdt.3	-	5	1044	c.1012C>T	c.(1012-1014)CGA>TGA	p.R338*	C9orf5_uc004bds.3_RNA|C9orf5_uc004bdr.3_Nonsense_Mutation_p.R338*	NM_032012	NP_114401	Q9H330	CI005_HUMAN	hypothetical protein LOC23731	338						integral to membrane				central_nervous_system(1)	1		Myeloproliferative disorder(63;0.204)		OV - Ovarian serous cystadenocarcinoma(323;3.08e-05)|STAD - Stomach adenocarcinoma(157;0.0823)		TCAGGCCTTCGTCTGCCCAGA	0.502000													13	60					0	0	1	0	0
C9orf171	389799	broad.mit.edu	37	9	135447853	135447853	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr9:135447853G>A	uc004cbn.2	+	7	967	c.919G>A	c.(919-921)GTG>ATG	p.V307M	C9orf171_uc004cbo.2_Missense_Mutation_p.V271M	NM_207417	NP_997300	Q6ZQR2	CI171_HUMAN	hypothetical protein LOC389799	307										ovary(4)|large_intestine(1)	5						AGAGTGTGCCGTGCGCCAGGG	0.602000													24	28					0	0	1	0	0
SNAPC4	6621	broad.mit.edu	37	9	139273027	139273027	+	Silent	SNP	C	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr9:139273027C>G	uc004chh.2	-	21	3261	c.3252G>C	c.(3250-3252)GGG>GGC	p.G1084G		NM_003086	NP_003077	Q5SXM2	SNPC4_HUMAN	small nuclear RNA activating complex,	1084	Pro-rich.				snRNA transcription from RNA polymerase II promoter|snRNA transcription from RNA polymerase III promoter	snRNA-activating protein complex	DNA binding|sequence-specific DNA binding transcription factor activity				0		Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;5.31e-06)|Epithelial(140;7.13e-06)		CAGGGAGAAGCCCCTGGGCTG	0.687000													3	10					0	0	1	0	0
ZFY	7544	broad.mit.edu	37	Y	2843189	2843189	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chrY:2843189G>C	uc004fqj.2	+	4	1009	c.688G>C	c.(688-690)GCA>CCA	p.A230P	ZFY_uc010nwd.1_Missense_Mutation_p.A230P|ZFY_uc011nan.1_Missense_Mutation_p.A39P|ZFY_uc010nwe.2_Missense_Mutation_p.A204P	NM_003411	NP_003402	P08048	ZFY_HUMAN	zinc finger protein, Y-linked isoform 1	230					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0						GACCATCGATGCAGAATCAGA	0.398000													2	9					0	0	1	0	0
RSC1A1	6248	broad.mit.edu	37	1	15987648	15987648	+	Silent	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr1:15987648T>C	uc010obn.1	+	1	1285	c.1285T>C	c.(1285-1287)TTA>CTA	p.L429L		NM_006511	NP_006502	Q92681	RSCA1_HUMAN	regulatory solute carrier protein, family 1,	429					negative regulation of transport|regulation of transcription, DNA-dependent|transcription, DNA-dependent|transport	cell junction|Golgi apparatus|nucleus	ion channel inhibitor activity			ovary(1)	1		Colorectal(325;0.00108)|Renal(390;0.00145)|Breast(348;0.00276)|Lung NSC(340;0.00566)|all_lung(284;0.00831)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0798)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;5.73e-07)|COAD - Colon adenocarcinoma(227;3.49e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000114)|KIRC - Kidney renal clear cell carcinoma(229;0.00244)|STAD - Stomach adenocarcinoma(313;0.0072)|READ - Rectum adenocarcinoma(331;0.0649)		GACAGAAAAATTAACAGGTAC	0.433000													30	37					0	0	1	0	0
PGM1	5236	broad.mit.edu	37	1	64117371	64117371	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr1:64117371G>A	uc001dbh.2	+	9	1525	c.1312G>A	c.(1312-1314)GCA>ACA	p.A438T	PGM1_uc010ooy.1_Missense_Mutation_p.A241T|PGM1_uc010ooz.1_Missense_Mutation_p.A456T	NM_002633	NP_002624	P36871	PGM1_HUMAN	phosphoglucomutase 1	438					cellular calcium ion homeostasis|galactose catabolic process|glucose 1-phosphate metabolic process|glycogen biosynthetic process|glycogen catabolic process	cytosol	magnesium ion binding|phosphoglucomutase activity			ovary(2)|kidney(1)	3						AGCTGAGGGCGCAAACAAAAT	0.512000													3	33					0	0	1	0	0
KIAA1614	57710	broad.mit.edu	37	1	180885553	180885553	+	Missense_Mutation	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr1:180885553C>T	uc001gok.2	+	2	381	c.314C>T	c.(313-315)TCT>TTT	p.S105F		NM_020950	NP_066001	Q5VZ46	K1614_HUMAN	hypothetical protein LOC57710	105										ovary(3)|skin(1)	4						AGTCCCTGCTCTGCTTCCCAA	0.587000													39	52					0	0	1	0	0
C1orf25	81627	broad.mit.edu	37	1	185094118	185094118	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr1:185094118T>A	uc001grf.3	-	12	1989	c.1717A>T	c.(1717-1719)AGT>TGT	p.S573C	C1orf25_uc010pon.1_Missense_Mutation_p.S417C	NM_030934	NP_112196	Q7Z2T5	TRM1L_HUMAN	N2,N2-dimethylguanosine tRNA	573						intracellular	RNA binding|tRNA (guanine-N2-)-methyltransferase activity|zinc ion binding				0						GAAAACTGACTTTGAGGCGTA	0.358000													35	59					0	0	1	0	0
C1orf150	148823	broad.mit.edu	37	1	247737622	247737622	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr1:247737622T>C	uc001idf.2	+	5	391	c.346T>C	c.(346-348)TCT>CCT	p.S116P	C1orf150_uc009xgw.2_RNA|C1orf150_uc001ida.3_RNA|C1orf150_uc001idb.3_RNA|C1orf150_uc009xgx.2_RNA	NM_145278	NP_660321	Q5JQS6	CA150_HUMAN	hypothetical protein LOC148823	116											0	all_cancers(71;3.24e-05)|all_epithelial(71;1.3e-05)|Breast(184;0.0149)|Ovarian(71;0.0377)|all_lung(81;0.0662)|Lung NSC(105;0.0724)		OV - Ovarian serous cystadenocarcinoma(106;0.0241)			TCTTAGGACTTCTGTTAGTAG	0.433000													32	49					0	0	1	0	0
GTPBP4	23560	broad.mit.edu	37	10	1061760	1061760	+	Missense_Mutation	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr10:1061760C>A	uc001ift.2	+	16	1747	c.1676C>A	c.(1675-1677)GCT>GAT	p.A559D	GTPBP4_uc001ifu.2_RNA|GTPBP4_uc010qad.1_Missense_Mutation_p.A443D|GTPBP4_uc010qae.1_Missense_Mutation_p.A512D	NM_012341	NP_036473	Q9BZE4	NOG1_HUMAN	G protein-binding protein CRFG	559					negative regulation of cell migration|negative regulation of cell proliferation|negative regulation of cell-cell adhesion|negative regulation of collagen binding|negative regulation of DNA replication|negative regulation of protein ubiquitination|protein stabilization|regulation of cyclin-dependent protein kinase activity|ribosome biogenesis	nucleolus|perinuclear region of cytoplasm	GTP binding|GTPase activity|protein binding			ovary(1)|skin(1)	2		all_epithelial(10;0.107)|Colorectal(49;0.14)	OV - Ovarian serous cystadenocarcinoma(33;0.0814)	Epithelial(11;0.0513)|all cancers(11;0.135)|OV - Ovarian serous cystadenocarcinoma(14;0.173)		GAAGACTCTGCTCCCCCGTCC	0.552000													52	99					1.07234e-20	1.21375e-20	1	1	0
KLF6	1316	broad.mit.edu	37	10	3822362	3822362	+	Missense_Mutation	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr10:3822362C>T	uc001iha.2	-	3	1003	c.736G>A	c.(736-738)GAG>AAG	p.E246K	KLF6_uc010qaj.1_Intron|KLF6_uc010qak.1_RNA|KLF6_uc010qal.1_Missense_Mutation_p.E204K	NM_001300	NP_001291	Q99612	KLF6_HUMAN	Kruppel-like factor 6 isoform A	246	C2H2-type 2.				B cell differentiation	nucleus	zinc ion binding			central_nervous_system(3)|lung(1)	4				Colorectal(1;0.238)		CTGGTTAACTCATCACTTCTT	0.542000													19	47					0	0	1	0	0
KIN	22944	broad.mit.edu	37	10	7829859	7829859	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr10:7829859G>C	uc001ijt.2	-	1	86	c.38C>G	c.(37-39)GCC>GGC	p.A13G	KIN_uc010qaz.1_RNA|KIN_uc009xip.2_Missense_Mutation_p.A13G|KIN_uc010qba.1_5'UTR|ATP5C1_uc010qbb.1_5'Flank|ATP5C1_uc009xiq.1_5'Flank|ATP5C1_uc010qbc.1_5'Flank|ATP5C1_uc001iju.2_5'Flank|ATP5C1_uc001ijv.2_5'Flank	NM_012311	NP_036443	O60870	KIN17_HUMAN	HsKin17 protein	13					DNA recombination|DNA repair|DNA replication|interspecies interaction between organisms|mRNA processing	cytoplasm|nuclear matrix	double-stranded DNA binding|RNA binding|zinc ion binding			ovary(1)|pancreas(1)|skin(1)	3						GATCCTGTTGGCGATAGCCTT	0.612000													54	67					0	0	1	0	0
MGEA5	10724	broad.mit.edu	37	10	103563517	103563517	+	Silent	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr10:103563517A>G	uc001ktv.2	-	7	1454	c.1011T>C	c.(1009-1011)AAT>AAC	p.N337N	MGEA5_uc010qqe.1_Silent_p.N337N|MGEA5_uc009xws.2_Silent_p.N337N|MGEA5_uc001ktw.2_Silent_p.N337N|MGEA5_uc009xwt.2_Intron	NM_012215	NP_036347	O60502	NCOAT_HUMAN	meningioma expressed antigen 5 (hyaluronidase)	337					glycoprotein catabolic process	cytoplasm|nucleus	histone acetyltransferase activity|hyalurononglucosaminidase activity			ovary(2)|skin(1)	3		Colorectal(252;0.207)		Epithelial(162;4.67e-09)|all cancers(201;2.54e-07)		TTCTCACTCCATTCATGTTTG	0.438000													9	102					0	0	1	0	0
DCHS1	8642	broad.mit.edu	37	11	6662595	6662595	+	Missense_Mutation	SNP	C	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr11:6662595C>G	uc001mem.1	-	2	660	c.250G>C	c.(250-252)GAG>CAG	p.E84Q		NM_003737	NP_003728	Q96JQ0	PCD16_HUMAN	dachsous 1 precursor	84	Cadherin 1.|Extracellular (Potential).				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(3)|large_intestine(1)|pancreas(1)	5		Medulloblastoma(188;0.00263)|all_neural(188;0.026)		Epithelial(150;6.35e-09)|BRCA - Breast invasive adenocarcinoma(625;0.135)		CCGCTGCCCTCTTGGGCAGAG	0.627000													16	25					0	0	1	0	0
OR5F1	338674	broad.mit.edu	37	11	55761615	55761615	+	Missense_Mutation	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr11:55761615C>T	uc010riv.1	-	1	487	c.487G>A	c.(487-489)GTC>ATC	p.V163I		NM_003697	NP_003688	O95221	OR5F1_HUMAN	olfactory receptor, family 5, subfamily F,	163	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|pancreas(1)	2	Esophageal squamous(21;0.00448)					AAGCTGCTGACATGGCTTGTG	0.483000													40	54					0	0	1	0	0
OR5F1	338674	broad.mit.edu	37	11	55761636	55761636	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr11:55761636A>C	uc010riv.1	-	1	466	c.466T>G	c.(466-468)TTC>GTC	p.F156V		NM_003697	NP_003688	O95221	OR5F1_HUMAN	olfactory receptor, family 5, subfamily F,	156	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|pancreas(1)	2	Esophageal squamous(21;0.00448)					TTGACCATGAAGTTCAGCAAC	0.507000													28	57					0	0	1	0	0
MYO7A	4647	broad.mit.edu	37	11	76903188	76903188	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr11:76903188C>T	uc001oyb.2	+	31	4289	c.4017C>T	c.(4015-4017)AAC>AAT	p.N1339N	MYO7A_uc010rsm.1_Silent_p.N1328N|MYO7A_uc001oyc.2_Silent_p.N1339N|MYO7A_uc009yus.1_RNA|MYO7A_uc009yut.1_Silent_p.N550N	NM_000260	NP_000251	Q13402	MYO7A_HUMAN	myosin VIIA isoform 1	1339	FERM 1.				actin filament-based movement|equilibrioception|lysosome organization|sensory perception of sound|visual perception	cytosol|lysosomal membrane|myosin complex|photoreceptor inner segment|photoreceptor outer segment|synapse	actin binding|ATP binding|calmodulin binding|microfilament motor activity			ovary(3)|breast(1)	4						AGGAGCGCAACGCCCCCTGGA	0.662000											OREG0021258	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	32	39					0	0	1	0	0
PRDM10	56980	broad.mit.edu	37	11	129817185	129817185	+	Silent	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr11:129817185G>A	uc001qfm.2	-	5	607	c.375C>T	c.(373-375)ACC>ACT	p.T125T	PRDM10_uc001qfj.2_Silent_p.T39T|PRDM10_uc001qfk.2_Silent_p.T39T|PRDM10_uc001qfl.2_Silent_p.T39T|PRDM10_uc010sbx.1_Silent_p.T39T|PRDM10_uc001qfn.2_Silent_p.T125T|PRDM10_uc009zct.1_Silent_p.T157T	NM_020228	NP_064613	Q9NQV6	PRD10_HUMAN	PR domain containing 10 isoform 1	125					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			pancreas(1)	1	all_hematologic(175;0.0537)	Breast(109;0.000496)|Lung NSC(97;0.000693)|all_lung(97;0.00151)|Medulloblastoma(222;0.0425)|all_neural(223;0.0837)		OV - Ovarian serous cystadenocarcinoma(99;0.0174)|Lung(977;0.176)|LUSC - Lung squamous cell carcinoma(976;0.185)		TGCCTAGAGGGGTCTGCAGAG	0.547000													27	43					0	0	1	0	0
LRP1	4035	broad.mit.edu	37	12	57573720	57573720	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr12:57573720G>A	uc001snd.2	+	30	5588	c.5122G>A	c.(5122-5124)GTC>ATC	p.V1708I		NM_002332	NP_002323	Q07954	LRP1_HUMAN	low density lipoprotein-related protein 1	1708	Extracellular (Potential).|LDL-receptor class B 14.				aorta morphogenesis|apoptotic cell clearance|negative regulation of platelet-derived growth factor receptor-beta signaling pathway|negative regulation of smooth muscle cell migration|negative regulation of Wnt receptor signaling pathway|positive regulation of cholesterol efflux|regulation of actin cytoskeleton organization|regulation of phospholipase A2 activity	coated pit|integral to plasma membrane|nucleus	apolipoprotein E binding|calcium ion binding|lipoprotein transporter activity|protein complex binding|receptor activity			ovary(8)|lung(3)|breast(3)|large_intestine(2)|central_nervous_system(2)|skin(2)|pancreas(2)	22				BRCA - Breast invasive adenocarcinoma(357;0.0103)	Alteplase(DB00009)|Anistreplase(DB00029)|Antihemophilic Factor(DB00025)|Becaplermin(DB00102)|Coagulation Factor IX(DB00100)|Tenecteplase(DB00031)	CCATGGCCTTGTCGTCCACCC	0.622000													47	64					0	0	1	0	0
C12orf51	283450	broad.mit.edu	37	12	112668608	112668608	+	Silent	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr12:112668608G>A	uc009zwc.2	-	33	4971	c.4953C>T	c.(4951-4953)CCC>CCT	p.P1651P	C12orf51_uc001ttr.1_5'Flank	NM_001109662	NP_001103132			chromosome 12 open reading frame 51											ovary(1)|lung(1)	2						CACTGATGAAGGGACGCACAG	0.498000													5	8					0	0	1	0	0
MTMR6	9107	broad.mit.edu	37	13	25823587	25823587	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr13:25823587G>C	uc001uqf.3	-	14	1968	c.1649C>G	c.(1648-1650)ACC>AGC	p.T550S	MTMR6_uc001uqe.1_Intron	NM_004685	NP_004676	Q9Y217	MTMR6_HUMAN	myotubularin related protein 6	550						cytoplasm|nuclear envelope	calcium-activated potassium channel activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity			ovary(2)|skin(2)	4		Lung SC(185;0.0225)|Breast(139;0.0351)		all cancers(112;0.00927)|Epithelial(112;0.0474)|OV - Ovarian serous cystadenocarcinoma(117;0.164)		CAATTCCTTGGTGAGGATGCC	0.353000													23	30					0	0	1	0	0
IPO5	3843	broad.mit.edu	37	13	98652854	98652854	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr13:98652854G>A	uc001vnf.1	+	10	1128	c.1063G>A	c.(1063-1065)GTT>ATT	p.V355I	IPO5_uc001vne.2_Missense_Mutation_p.V373I|IPO5_uc010tik.1_Missense_Mutation_p.V230I|IPO5_uc010til.1_Missense_Mutation_p.V295I|IPO5_uc001vng.1_5'Flank	NM_002271	NP_002262	O00410	IPO5_HUMAN	importin 5	355	Ran-GTP binding (By similarity).				interspecies interaction between organisms|NLS-bearing substrate import into nucleus|ribosomal protein import into nucleus	cytoplasm|nuclear pore|nucleolus	GTPase inhibitor activity|protein transporter activity|Ran GTPase binding			ovary(1)|lung(1)|skin(1)	3						TGGAAAGCTCGTTCTGCCGAT	0.418000													29	26					0	0	1	0	0
FARP1	10160	broad.mit.edu	37	13	99037979	99037979	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr13:99037979A>C	uc001vnj.2	+	8	1006	c.670A>C	c.(670-672)ATG>CTG	p.M224L	FARP1_uc001vnh.2_Missense_Mutation_p.M224L	NM_005766	NP_005757	Q9Y4F1	FARP1_HUMAN	FERM, RhoGEF, and pleckstrin domain protein 1	224	FERM.				regulation of Rho protein signal transduction	cytoplasm|cytoskeleton|extrinsic to membrane	cytoskeletal protein binding|Rho guanyl-nucleotide exchange factor activity			breast(2)	2	all_neural(89;0.0982)|Medulloblastoma(90;0.163)|Lung SC(71;0.184)		BRCA - Breast invasive adenocarcinoma(86;0.233)			TCGGCTAGAGATGTATGGAAT	0.488000													35	60					0	0	1	0	0
RYR3	6263	broad.mit.edu	37	15	33961646	33961646	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr15:33961646T>C	uc001zhi.2	+	37	5781	c.5711T>C	c.(5710-5712)CTC>CCC	p.L1904P	RYR3_uc010bar.2_Missense_Mutation_p.L1904P	NM_001036	NP_001027	Q15413	RYR3_HUMAN	ryanodine receptor 3	1904	4 X approximate repeats.|Cytoplasmic (By similarity).				cellular calcium ion homeostasis	integral to membrane	calcium ion binding|receptor activity|ryanodine-sensitive calcium-release channel activity			ovary(5)|central_nervous_system(4)|lung(1)	10		all_lung(180;7.18e-09)		all cancers(64;8.95e-12)|GBM - Glioblastoma multiforme(186;0.00109)|BRCA - Breast invasive adenocarcinoma(123;0.0363)		GAGGACCTTCTCCTTCACTGT	0.463000													20	29					0	0	1	0	0
ACTC1	70	broad.mit.edu	37	15	35085735	35085735	+	Silent	SNP	G	A	A	rs149432225		TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr15:35085735G>A	uc001ziu.1	-	3	408	c.165C>T	c.(163-165)TAC>TAT	p.Y55Y	uc001zit.1_Intron	NM_005159	NP_005150	P68032	ACTC_HUMAN	cardiac muscle alpha actin 1 proprotein	55					apoptosis|cardiac muscle tissue morphogenesis|cardiac myofibril assembly|muscle filament sliding|skeletal muscle thin filament assembly	actomyosin, actin part|cytosol|I band	ATP binding|ATPase activity|myosin binding			upper_aerodigestive_tract(1)|ovary(1)	2		all_lung(180;2.3e-08)		all cancers(64;5.83e-19)|GBM - Glioblastoma multiforme(113;1.98e-07)|BRCA - Breast invasive adenocarcinoma(123;0.0244)		CATCACCTACGTAGGAGTCCT	0.473000													31	33					0	0	1	0	0
THBS1	7057	broad.mit.edu	37	15	39885784	39885784	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr15:39885784T>C	uc001zkh.2	+	19	3361	c.3182T>C	c.(3181-3183)CTT>CCT	p.L1061P	THBS1_uc010bbi.2_Missense_Mutation_p.L533P	NM_003246	NP_003237	P07996	TSP1_HUMAN	thrombospondin 1 precursor	1061	TSP C-terminal.				activation of MAPK activity|anti-apoptosis|apoptosis|cell adhesion|cell cycle arrest|cell migration|cellular response to heat|chronic inflammatory response|engulfment of apoptotic cell|immune response|induction of apoptosis|negative regulation of angiogenesis|negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|negative regulation of blood vessel endothelial cell migration|negative regulation of caspase activity|negative regulation of cGMP-mediated signaling|negative regulation of dendritic cell antigen processing and presentation|negative regulation of endothelial cell proliferation|negative regulation of fibrinolysis|negative regulation of fibroblast growth factor receptor signaling pathway|negative regulation of focal adhesion assembly|negative regulation of interleukin-12 production|negative regulation of nitric oxide mediated signal transduction|negative regulation of plasma membrane long-chain fatty acid transport|negative regulation of plasminogen activation|peptide cross-linking|platelet activation|platelet degranulation|positive regulation of angiogenesis|positive regulation of blood vessel endothelial cell migration|positive regulation of fibroblast migration|positive regulation of macrophage activation|positive regulation of macrophage chemotaxis|positive regulation of phosphorylation|positive regulation of protein kinase B signaling cascade|positive regulation of reactive oxygen species metabolic process|positive regulation of transforming growth factor beta receptor signaling pathway|positive regulation of transforming growth factor-beta1 production|positive regulation of translation|positive regulation of tumor necrosis factor biosynthetic process|response to calcium ion|response to drug|response to glucose stimulus|response to hypoxia|response to magnesium ion|response to progesterone stimulus|sprouting angiogenesis	external side of plasma membrane|extracellular matrix|fibrinogen complex|platelet alpha granule lumen	calcium ion binding|collagen V binding|eukaryotic cell surface binding|fibrinogen binding|fibroblast growth factor 2 binding|fibronectin binding|heparin binding|identical protein binding|integrin binding|laminin binding|low-density lipoprotein particle binding|phosphatidylserine binding|proteoglycan binding|structural molecule activity|transforming growth factor beta binding			ovary(3)|central_nervous_system(3)	6		all_cancers(109;1.35e-17)|all_epithelial(112;2.07e-15)|Lung NSC(122;4.44e-11)|all_lung(180;1.11e-09)|Melanoma(134;0.0574)|Colorectal(260;0.117)|Ovarian(310;0.223)		GBM - Glioblastoma multiforme(113;2.77e-06)|BRCA - Breast invasive adenocarcinoma(123;0.105)	Becaplermin(DB00102)	TACTCGGGCCTTTCTGTGAAA	0.582000													62	104					0	0	1	0	0
HMG20A	10363	broad.mit.edu	37	15	77759508	77759508	+	Silent	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr15:77759508C>A	uc002bcr.2	+	5	510	c.309C>A	c.(307-309)CCC>CCA	p.P103P	HMG20A_uc002bcs.2_Silent_p.P103P	NM_018200	NP_060670	Q9NP66	HM20A_HUMAN	high-mobility group 20A	103	HMG box.				chromatin modification	nucleus	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			upper_aerodigestive_tract(1)|ovary(1)|central_nervous_system(1)	3						GCAATGCACCCAAATCCCCCC	0.403000													21	38					1.22574e-08	1.28828e-08	1	1	0
C15orf42	90381	broad.mit.edu	37	15	90118913	90118913	+	Silent	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr15:90118913C>A	uc002boe.2	+	1	96	c.96C>A	c.(94-96)ACC>ACA	p.T32T		NM_152259	NP_689472	Q7Z2Z1	TICRR_HUMAN	leucine-rich repeat kinase 1	32					cell cycle|DNA repair|DNA replication|formation of translation preinitiation complex|G2/M transition checkpoint|mitotic cell cycle DNA replication checkpoint|regulation of DNA-dependent DNA replication initiation|response to ionizing radiation	nucleus	chromatin binding|protein binding			ovary(4)|central_nervous_system(2)|skin(1)	7	Lung NSC(78;0.0237)|all_lung(78;0.0478)		BRCA - Breast invasive adenocarcinoma(143;0.128)			GCCTCCTCACCTATCTGAGTT	0.478000													4	9					0.00909568	0.00909568	1	1	0
Unknown	0	broad.mit.edu	37	15	101098922	101098922	+	RNA	SNP	T	C	C	rs9920217	by1000genomes	TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr15:101098922T>C	uc002bwc.1	+	1		c.38T>C								Homo sapiens cDNA clone IMAGE:4822975.																		GGAATGCTCATCAACTTGAGG	0.607000													4	43					0	0	1	0	0
MLST8	64223	broad.mit.edu	37	16	2258565	2258565	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr16:2258565C>T	uc002coz.2	+	8	932	c.813C>T	c.(811-813)GGC>GGT	p.G271G	MLST8_uc002coy.2_Silent_p.G271G|MLST8_uc002cpa.2_Silent_p.G87G|MLST8_uc002cpb.2_Silent_p.G270G|MLST8_uc010uvx.1_Silent_p.G205G|MLST8_uc002cpc.2_Silent_p.G271G|MLST8_uc002cpd.2_Silent_p.G205G|MLST8_uc002cpe.2_Silent_p.G271G|MLST8_uc002cpg.2_Silent_p.G290G|MLST8_uc002cph.2_RNA|MLST8_uc002cpf.2_Silent_p.G271G	NM_022372	NP_071767	Q9BVC4	LST8_HUMAN	G protein beta subunit-like	271	WD 7.				insulin receptor signaling pathway|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of TOR signaling cascade|T cell costimulation	cytosol	protein binding				0						CCTCCCGCGGCTGGATGTGGG	0.677000													41	129					0	0	1	0	0
PPP4C	5531	broad.mit.edu	37	16	30094761	30094761	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr16:30094761G>A	uc002dwe.2	+	6	494	c.350G>A	c.(349-351)AGT>AAT	p.S117N	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|PPP4C_uc002dwf.2_Missense_Mutation_p.S117N|PPP4C_uc002dwg.2_RNA|PPP4C_uc002dwh.2_Missense_Mutation_p.S38N	NM_002720	NP_002711	P60510	PP4C_HUMAN	protein phosphatase 4, catalytic subunit	117					microtubule cytoskeleton organization|regulation of double-strand break repair via homologous recombination	centrosome|nucleus	metal ion binding|NF-kappaB-inducing kinase activity|protein binding|protein serine/threonine phosphatase activity			skin(1)	1						AACCATGAGAGTCGCCAGATC	0.592000													88	59					0	0	1	0	0
Unknown	0	broad.mit.edu	37	16	32070612	32070612	+	RNA	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr16:32070612A>C	uc002ecv.1	+	1		c.65A>C								Homo sapiens IGH mRNA for immunoglobulin heavy chain VHDJ region, partial cds, clone:TRH1-22.																		GGTCTCCTGCAAGGCTTCTGG	0.552000													8	101					0	0	1	0	0
MARVELD3	91862	broad.mit.edu	37	16	71663293	71663293	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr16:71663293T>A	uc002fat.2	+	2	554	c.491T>A	c.(490-492)CTG>CAG	p.L164Q	MARVELD3_uc002fas.1_Missense_Mutation_p.L164Q|MARVELD3_uc002fau.2_Missense_Mutation_p.L164Q|MARVELD3_uc010cge.2_Missense_Mutation_p.C110S	NM_052858	NP_443090	Q96A59	MALD3_HUMAN	MARVEL domain containing 3 isoform 2	164	Pro-rich.|Cytoplasmic (Potential).					integral to membrane				skin(1)	1		Ovarian(137;0.125)				GAGAGATATCTGCCCTCGACC	0.502000													5	100					0	0	1	0	0
ABR	29	broad.mit.edu	37	17	916353	916353	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr17:916353T>C	uc002fsd.2	-	17	1953	c.1843A>G	c.(1843-1845)ATG>GTG	p.M615V	ABR_uc002fse.2_Missense_Mutation_p.M569V|ABR_uc010vqf.1_Missense_Mutation_p.M66V|ABR_uc010vqg.1_Missense_Mutation_p.M397V|ABR_uc002fsg.2_Missense_Mutation_p.M578V|ABR_uc002fsh.1_Intron|ABR_uc002fsf.2_5'Flank	NM_021962	NP_068781	Q12979	ABR_HUMAN	active breakpoint cluster region-related	615					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity|protein binding|Rho guanyl-nucleotide exchange factor activity			upper_aerodigestive_tract(1)	1				UCEC - Uterine corpus endometrioid carcinoma (25;0.0228)		ACCCCGTTCATCTCAATCACG	0.632000													34	78					0	0	1	0	0
CTNS	1497	broad.mit.edu	37	17	3550808	3550808	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr17:3550808C>T	uc002fwb.2	+	4	725	c.132C>T	c.(130-132)CTC>CTT	p.L44L	CTNS_uc002fwa.2_Silent_p.L44L|CTNS_uc010ckj.2_Silent_p.L44L|CTNS_uc010vrv.1_Intron|CTNS_uc010vrw.1_Intron	NM_004937	NP_004928	O60931	CTNS_HUMAN	cystinosin isoform 2	44	Lumenal (Potential).				ATP metabolic process|brain development|cognition|glutathione metabolic process	integral to membrane|late endosome|lysosomal membrane	L-cystine transmembrane transporter activity				0				COAD - Colon adenocarcinoma(5;0.0829)	L-Cystine(DB00138)	ACGTCAGCCTCACCCTGCGGT	0.602000													13	69					0	0	1	0	0
GPR179	440435	broad.mit.edu	37	17	36486249	36486249	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr17:36486249A>C	uc002hpz.2	-	11	3224	c.3203T>G	c.(3202-3204)ATC>AGC	p.I1068S		NM_001004334	NP_001004334	Q6PRD1	GP179_HUMAN	GPR158-like 1 precursor	1068	Cytoplasmic (Potential).					integral to membrane|plasma membrane	G-protein coupled receptor activity			ovary(3)	3	Breast(7;2.97e-12)	Breast(25;0.0101)|Ovarian(249;0.15)				TTTAGGGAAGATCTTGGGCCT	0.562000													26	72					0	0	1	0	0
KRTAP4-9	100132386	broad.mit.edu	37	17	39262103	39262103	+	Missense_Mutation	SNP	A	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr17:39262103A>T	uc010wfp.1	+	1	463	c.463A>T	c.(463-465)AGC>TGC	p.S155C		NM_001146041	NP_001139513	Q9BYQ8	KRA49_HUMAN	keratin associated protein 4-9	155	29 X 5 AA repeats of C-C-[RQVHIEK]- [SPTR]-[VSTQCRNP].					keratin filament					0						ccccagctgcagcatctccag	0.124000													3	31					0	0	1	0	0
MYO5B	4645	broad.mit.edu	37	18	47369741	47369741	+	Missense_Mutation	SNP	G	A	A	rs139632666	by1000genomes	TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr18:47369741G>A	uc002leb.2	-	34	4769	c.4481C>T	c.(4480-4482)TCG>TTG	p.S1494L	MYO5B_uc002ldz.2_Missense_Mutation_p.S64L|MYO5B_uc002lea.2_Missense_Mutation_p.S609L	NM_001080467	NP_001073936	Q9ULV0	MYO5B_HUMAN	myosin VB	1494					protein transport	myosin complex	actin binding|ATP binding|calmodulin binding|motor activity			ovary(2)|skin(2)|central_nervous_system(1)	5				READ - Rectum adenocarcinoma(32;0.103)		CACTGTGCCCGACAGCATCTG	0.557000													5	67					0	0	1	0	0
LOC284441	284441	broad.mit.edu	37	19	20369503	20369503	+	Missense_Mutation	SNP	C	G	G	rs8103002	by1000genomes	TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr19:20369503C>G	uc002nov.2	+	1	1047	c.296C>G	c.(295-297)GCT>GGT	p.A99G		NR_003128				SubName: Full=cDNA FLJ51655, highly similar to Actin-like protein 2;												0						TTATTGACTGCTGTAGTGGTA	0.458000													6	112					0	0	1	0	0
IL29	282618	broad.mit.edu	37	19	39787490	39787490	+	Missense_Mutation	SNP	T	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr19:39787490T>G	uc002okv.2	+	2	314	c.217T>G	c.(217-219)TTC>GTC	p.F73V		NM_172140	NP_742152	Q8IU54	IL29_HUMAN	interleukin 29 precursor	73					defense response to virus|negative regulation of cell proliferation|negative regulation of interleukin-13 production|negative regulation of interleukin-5 production|negative regulation of memory T cell differentiation|negative regulation of transcription, DNA-dependent|negative regulation of type 2 immune response|positive regulation of immune response|positive regulation of interferon-gamma production|positive regulation of MHC class I biosynthetic process|positive regulation of transcription, DNA-dependent|positive regulation of tyrosine phosphorylation of STAT protein	extracellular space|interleukin-28 receptor complex	cytokine activity|interleukin-28 receptor binding				0	all_cancers(60;1.85e-07)|all_lung(34;4.03e-08)|Lung NSC(34;4.66e-08)|all_epithelial(25;6.4e-07)|Ovarian(47;0.0512)		Epithelial(26;1.96e-27)|all cancers(26;2.05e-24)|Lung(45;0.000278)|LUSC - Lung squamous cell carcinoma(53;0.000335)			CTCTCCTGTCTTCCCCGGGAA	0.572000													18	24					0	0	1	0	0
PRR19	284338	broad.mit.edu	37	19	42814766	42814766	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr19:42814766C>T	uc002oti.2	+	3	1323	c.945C>T	c.(943-945)CCC>CCT	p.P315P	PRR19_uc002oth.1_3'UTR|PRR19_uc002otj.2_Silent_p.P315P|TMEM145_uc002otk.1_5'Flank	NM_199285	NP_954979	A6NJB7	PRR19_HUMAN	proline rich 19	315	Pro-rich.										0		Prostate(69;0.00682)				CTTCATCACCCCTGTTGCCCC	0.652000													71	113					0	0	1	0	0
RSPH6A	81492	broad.mit.edu	37	19	46317875	46317875	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr19:46317875G>C	uc002pdm.2	-	1	703	c.560C>G	c.(559-561)GCC>GGC	p.A187G		NM_030785	NP_110412	Q9H0K4	RSH6A_HUMAN	radial spokehead-like 1	187						intracellular				ovary(1)|central_nervous_system(1)	2						AGGCACCTGGGCACTGTAGTG	0.612000													23	38					0	0	1	0	0
PEG3	5178	broad.mit.edu	37	19	57325186	57325186	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr19:57325186A>G	uc002qnu.2	-	7	4975	c.4624T>C	c.(4624-4626)TGC>CGC	p.C1542R	ZIM2_uc010ygq.1_Intron|ZIM2_uc010ygr.1_Intron|ZIM2_uc002qnr.2_Intron|ZIM2_uc002qnq.2_Intron|ZIM2_uc010etp.2_Intron|ZIM2_uc010ygs.1_Intron|PEG3_uc002qnt.2_Missense_Mutation_p.C1513R|PEG3_uc002qnv.2_Missense_Mutation_p.C1542R|PEG3_uc002qnw.2_Missense_Mutation_p.C1418R|PEG3_uc002qnx.2_Missense_Mutation_p.C1416R|PEG3_uc010etr.2_Missense_Mutation_p.C1542R	NM_001146186	NP_001139658	Q9GZU2	PEG3_HUMAN	paternally expressed 3 isoform 1	1542					apoptosis|viral reproduction	cytoplasm|nucleus	nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(7)|skin(2)|upper_aerodigestive_tract(1)|large_intestine(1)|pancreas(1)	12		Colorectal(82;0.000256)|all_neural(62;0.103)|Ovarian(87;0.243)		GBM - Glioblastoma multiforme(193;0.0269)		TAGCCTGAGCACTCCCCAAAG	0.488000													28	73					0	0	1	0	0
ASAP2	8853	broad.mit.edu	37	2	9528579	9528579	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr2:9528579T>C	uc002qzh.2	+	22	2627	c.2287T>C	c.(2287-2289)TAC>CAC	p.Y763H	ASAP2_uc002qzi.2_Missense_Mutation_p.Y763H	NM_003887	NP_003878	O43150	ASAP2_HUMAN	ArfGAP with SH3 domain, ankyrin repeat and PH	763					regulation of ARF GTPase activity	Golgi cisterna membrane|plasma membrane	ARF GTPase activator activity|protein binding|zinc ion binding				0						GAATGAGACTTACGGAGCCCT	0.597000													18	25					0	0	1	0	0
SLC4A1AP	22950	broad.mit.edu	37	2	27888159	27888159	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr2:27888159A>G	uc002rlk.3	+	2	1300	c.1018A>G	c.(1018-1020)ATG>GTG	p.M340V	SUPT7L_uc002rlh.1_5'Flank|SUPT7L_uc002rli.1_5'Flank|SUPT7L_uc010ymf.1_5'Flank|SUPT7L_uc002rlj.1_5'Flank|SUPT7L_uc010ezh.1_5'Flank	NM_018158	NP_060628	Q9BWU0	NADAP_HUMAN	solute carrier family 4 (anion exchanger),	340						cytoplasm|nucleus	double-stranded RNA binding|protein binding				0	Acute lymphoblastic leukemia(172;0.155)					CACCTGGGGAATGGGTAAGAA	0.383000													49	55					0	0	1	0	0
GPR75	10936	broad.mit.edu	37	2	54080607	54080607	+	Silent	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr2:54080607A>G	uc002rxo.3	-	2	1558	c.1287T>C	c.(1285-1287)TCT>TCC	p.S429S	ASB3_uc002rxi.3_Intron	NM_006794	NP_006785	O95800	GPR75_HUMAN	G protein-coupled receptor 75	429	Cytoplasmic (Potential).					integral to plasma membrane	G-protein coupled receptor activity			ovary(1)|skin(1)	2			Lung(47;0.125)|LUSC - Lung squamous cell carcinoma(58;0.181)			ACATGTAGGCAGAGTTTGTTT	0.448000													46	131					0	0	1	0	0
USP39	10713	broad.mit.edu	37	2	85875075	85875075	+	Nonsense_Mutation	SNP	T	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr2:85875075T>G	uc002sqe.2	+	12	1622	c.1586T>G	c.(1585-1587)TTA>TGA	p.L529*	USP39_uc002sqb.2_Nonsense_Mutation_p.L260*|USP39_uc010ysu.1_Nonsense_Mutation_p.L451*|USP39_uc010ysv.1_Nonsense_Mutation_p.L426*|USP39_uc002sqf.2_Intron|USP39_uc002sqg.2_Nonsense_Mutation_p.L529*|USP39_uc010fgo.2_Missense_Mutation_p.Y484D	NM_006590	NP_006581	Q53GS9	SNUT2_HUMAN	ubiquitin specific protease 39	529					spliceosome assembly|ubiquitin-dependent protein catabolic process	nucleus	protein binding|ubiquitin thiolesterase activity|zinc ion binding			ovary(1)	1						TGGTATGAATTACAAGACCTC	0.478000													36	47					0	0	1	0	0
MBD5	55777	broad.mit.edu	37	2	149248040	149248040	+	Silent	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr2:149248040A>C	uc002twm.3	+	12	5128	c.4140A>C	c.(4138-4140)CCA>CCC	p.P1380P	MBD5_uc010zbs.1_Intron|MBD5_uc010fns.2_Silent_p.P1380P|MBD5_uc002two.2_Silent_p.P638P|MBD5_uc002twp.2_Silent_p.P430P	NM_018328	NP_060798	Q9P267	MBD5_HUMAN	methyl-CpG binding domain protein 5	1380						chromosome|nucleus	chromatin binding|DNA binding			skin(3)|ovary(2)	5				BRCA - Breast invasive adenocarcinoma(221;0.0569)		ATTATAGACCAAGGACGTTCA	0.453000													45	55					0	0	1	0	0
PAX3	5077	broad.mit.edu	37	2	223066673	223066673	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr2:223066673C>T	uc010fwo.2	-	8	1776	c.1410G>A	c.(1408-1410)CAG>CAA	p.Q470Q	PAX3_uc002vmt.1_Silent_p.Q470Q|PAX3_uc002vmy.1_Silent_p.Q469Q|PAX3_uc002vmv.1_Silent_p.Q470Q|PAX3_uc002vmw.1_Intron|PAX3_uc002vmx.1_Intron	NM_181457	NP_852122	P23760	PAX3_HUMAN	paired box 3 isoform PAX3	470					apoptosis|organ morphogenesis|positive regulation of transcription from RNA polymerase II promoter|sensory perception of sound|transcription from RNA polymerase II promoter	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity		PAX3/FOXO1(749)|PAX3/NCOA1(8)|PAX3/NCOA2(4)	soft_tissue(761)|ovary(4)|skin(1)	766		Renal(207;0.0183)		Epithelial(121;4.13e-10)|all cancers(144;1.85e-07)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		TTTGTCCATACTGCCCATATT	0.468000			T	FOXO1A|NCOA1	alveolar rhabdomyosarcoma		Waardenburg syndrome; craniofacial-deafness-hand syndrome						6	66					0	0	1	0	0
SAMHD1	25939	broad.mit.edu	37	20	35532631	35532631	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr20:35532631T>C	uc002xgh.1	-	13	1562	c.1432A>G	c.(1432-1434)AAA>GAA	p.K478E	SAMHD1_uc010gft.1_RNA	NM_015474	NP_056289	Q9Y3Z3	SAMH1_HUMAN	SAM domain- and HD domain-containing protein 1	478					defense response to virus|innate immune response|regulation of innate immune response	nucleus	metal ion binding|phosphoric diester hydrolase activity				0		Myeloproliferative disorder(115;0.00878)				GCAACCTCTTTTGGAAGAGAT	0.388000													101	72					0	0	1	0	0
POM121L9P	29774	broad.mit.edu	37	22	24659515	24659515	+	RNA	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr22:24659515G>A	uc002zzs.3	+	7		c.3247G>A			uc011ajp.1_5'Flank	NR_003714				Homo sapiens mRNA; cDNA DKFZp434P211 (from clone DKFZp434P211).												0						CTGGGCCATGGAGCACTCTGA	0.478000													7	11					0	0	1	0	0
CELSR3	1951	broad.mit.edu	37	3	48690562	48690562	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr3:48690562A>C	uc003cul.2	-	10	5788	c.5507T>G	c.(5506-5508)CTC>CGC	p.L1836R	CELSR3_uc003cuf.1_Missense_Mutation_p.L1906R|CELSR3_uc010hkg.2_5'Flank	NM_001407	NP_001398	Q9NYQ7	CELR3_HUMAN	cadherin EGF LAG seven-pass G-type receptor 3	1836	Extracellular (Potential).|Laminin G-like 2.				homophilic cell adhesion|multicellular organismal development|neuropeptide signaling pathway	integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein binding			ovary(5)|upper_aerodigestive_tract(2)|central_nervous_system(2)|skin(2)	11				BRCA - Breast invasive adenocarcinoma(193;0.000292)|KIRC - Kidney renal clear cell carcinoma(197;0.00549)|Kidney(197;0.00619)		GTCCAGAAGGAGATGGGAAGC	0.622000													25	32					0	0	1	0	0
FAM86D	692099	broad.mit.edu	37	3	75475709	75475709	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr3:75475709T>C	uc003dpp.3	-	7	888	c.529A>G	c.(529-531)ATC>GTC	p.I177V	FAM86D_uc003dpo.3_RNA|FAM86D_uc003dps.3_RNA|FAM86D_uc003dpq.3_Missense_Mutation_p.I85V|FAM86D_uc003dpr.3_RNA	NR_024241				RecName: Full=Protein FAM86B1;												0						CTCCGCAGGATCCCGACCAGC	0.562000													4	59					0	0	1	0	0
COL6A6	131873	broad.mit.edu	37	3	130292932	130292932	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr3:130292932T>A	uc010htl.2	+	7	3141	c.3110T>A	c.(3109-3111)GTG>GAG	p.V1037E		NM_001102608	NP_001096078	A6NMZ7	CO6A6_HUMAN	collagen type VI alpha 6 precursor	1037	Nonhelical region.|VWFA 6.				axon guidance|cell adhesion	collagen				ovary(6)|central_nervous_system(1)|pancreas(1)	8						CTCAACAGAGTGCGAATAGGA	0.418000													18	19					0	0	1	0	0
LRPAP1	4043	broad.mit.edu	37	4	3519768	3519768	+	Silent	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:3519768A>G	uc003ghi.2	-	5	829	c.744T>C	c.(742-744)ACT>ACC	p.T248T		NM_002337	NP_002328	P30533	AMRP_HUMAN	low density lipoprotein receptor-related protein	248	LDL receptor binding (Potential).|Potential.				negative regulation of protein binding|negative regulation of very-low-density lipoprotein particle clearance|protein folding|vesicle-mediated transport	cell surface|integral to membrane|plasma membrane	asialoglycoprotein receptor activity|heparin binding|low-density lipoprotein particle receptor binding|receptor antagonist activity|unfolded protein binding|very-low-density lipoprotein particle receptor binding			ovary(1)|skin(1)	2				UCEC - Uterine corpus endometrioid carcinoma (64;0.165)		CACCAGCCTCAGTGCTGTAGC	0.657000													10	27					0	0	1	0	0
TBC1D19	55296	broad.mit.edu	37	4	26737100	26737100	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:26737100T>A	uc003gsf.3	+	16	1378	c.1108T>A	c.(1108-1110)TCA>ACA	p.S370T	TBC1D19_uc010iew.2_Missense_Mutation_p.S370T|TBC1D19_uc011bxu.1_Missense_Mutation_p.S305T	NM_018317	NP_060787	Q8N5T2	TBC19_HUMAN	TBC1 domain family, member 19	370	Rab-GAP TBC.					intracellular	Rab GTPase activator activity			breast(1)	1		Breast(46;0.0503)				TCATGGATTTTCAATGTATGG	0.264000													4	11					0	0	1	0	0
UGT2B10	7365	broad.mit.edu	37	4	69870721	69870721	+	Silent	SNP	A	G	G	rs111542944		TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:69870721A>G	uc011cao.1	-	9	1465	c.1329T>C	c.(1327-1329)CAT>CAC	p.H443H	UGT2B10_uc011can.1_Silent_p.H359H			P36537	UDB10_HUMAN	RecName: Full=UDP-glucuronosyltransferase 2B28;          Short=UDPGT 2B28;          EC=2.4.1.17; Flags: Precursor;	480					lipid metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	glucuronosyltransferase activity			skin(3)|ovary(2)	5						AGGTGAGGTCATGGGCTGCAA	0.478000													6	161					0	0	1	0	0
AFF1	4299	broad.mit.edu	37	4	88029381	88029381	+	Missense_Mutation	SNP	G	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:88029381G>T	uc003hqj.3	+	10	1833	c.1426G>T	c.(1426-1428)GAC>TAC	p.D476Y	AFF1_uc011ccz.1_Missense_Mutation_p.D483Y|AFF1_uc003hqk.3_Missense_Mutation_p.D476Y|AFF1_uc011cda.1_Missense_Mutation_p.D114Y	NM_005935	NP_005926	P51825	AFF1_HUMAN	myeloid/lymphoid or mixed-lineage leukemia	476						nucleus	sequence-specific DNA binding transcription factor activity			breast(1)	1		Acute lymphoblastic leukemia(40;0.0935)|all_hematologic(202;0.111)|Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.000233)		AAGCACCAGTGACTCAGACAG	0.512000													20	36					3.8784e-16	4.29544e-16	1	1	0
SEC24B	10427	broad.mit.edu	37	4	110415933	110415933	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:110415933A>G	uc003hzk.2	+	6	1464	c.1409A>G	c.(1408-1410)TAT>TGT	p.Y470C	SEC24B_uc003hzl.2_Missense_Mutation_p.Y435C|SEC24B_uc011cfp.1_Missense_Mutation_p.Y501C|SEC24B_uc011cfq.1_Missense_Mutation_p.Y470C|SEC24B_uc011cfr.1_Missense_Mutation_p.Y435C	NM_006323	NP_006314	O95487	SC24B_HUMAN	SEC24 (S. cerevisiae) homolog B isoform a	470					COPII vesicle coating|intracellular protein transport|post-translational protein modification|protein N-linked glycosylation via asparagine	COPII vesicle coat|cytosol|endoplasmic reticulum membrane|Golgi membrane|perinuclear region of cytoplasm	protein binding|transporter activity|zinc ion binding			ovary(2)|large_intestine(1)	3		Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;3.03e-05)		CAGCCTGGTTATCAGAATGCT	0.473000													55	75					0	0	1	0	0
SPATA5	166378	broad.mit.edu	37	4	123848831	123848831	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:123848831A>G	uc003iez.3	+	2	279	c.206A>G	c.(205-207)CAT>CGT	p.H69R	SPATA5_uc003iey.2_Missense_Mutation_p.H68R	NM_145207	NP_660208	Q8NB90	SPAT5_HUMAN	spermatogenesis associated 5	69					cell differentiation|multicellular organismal development|spermatogenesis	mitochondrion	ATP binding|nucleoside-triphosphatase activity				0						TCCCTTATTCATCTTGGACTC	0.338000													51	58					0	0	1	0	0
TRIM2	23321	broad.mit.edu	37	4	154215496	154215496	+	Missense_Mutation	SNP	A	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:154215496A>T	uc003ing.2	+	5	765	c.564A>T	c.(562-564)GAA>GAT	p.E188D	TRIM2_uc003inh.2_Missense_Mutation_p.E215D	NM_001130067	NP_001123539	Q9C040	TRIM2_HUMAN	tripartite motif-containing 2 isoform 2	188						cytoplasm	zinc ion binding			central_nervous_system(1)	1	all_hematologic(180;0.093)	Medulloblastoma(177;0.00225)		GBM - Glioblastoma multiforme(119;0.0102)|LUSC - Lung squamous cell carcinoma(193;0.0703)		TCATCTCTGAAATCATTCATC	0.413000													29	42					0	0	1	0	0
DCHS2	54798	broad.mit.edu	37	4	155225827	155225827	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:155225827T>C	uc003inw.2	-	17	4234	c.4234A>G	c.(4234-4236)ATA>GTA	p.I1412V		NM_017639	NP_060109	Q6V1P9	PCD23_HUMAN	dachsous 2 isoform 1	1412	Cadherin 12.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(3)|pancreas(1)	4	all_hematologic(180;0.208)	Renal(120;0.0854)		LUSC - Lung squamous cell carcinoma(193;0.107)		TTACCAATTATGTGATATTCA	0.219000													23	23					0	0	1	0	0
LOC285501	285501	broad.mit.edu	37	4	178897009	178897009	+	RNA	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:178897009C>T	uc010iru.2	+	5		c.678C>T				NR_028342				Homo sapiens cDNA clone IMAGE:4828874.												0		all_lung(41;6.03e-08)|Lung NSC(41;4.26e-07)|Breast(14;0.00066)|Melanoma(52;0.00168)|Prostate(90;0.0129)|all_hematologic(60;0.0202)|Renal(120;0.0246)|Colorectal(36;0.0508)|Hepatocellular(41;0.236)		all cancers(43;9.24e-25)|Epithelial(43;6.28e-22)|OV - Ovarian serous cystadenocarcinoma(60;5.29e-10)|LUSC - Lung squamous cell carcinoma(1;2.61e-05)|Lung(1;3.22e-05)|GBM - Glioblastoma multiforme(59;0.000185)|Colorectal(24;0.000244)|STAD - Stomach adenocarcinoma(60;0.000777)|COAD - Colon adenocarcinoma(29;0.000884)		CACTGGGGCACGGGAAAGGGG	0.408000													5	117					0	0	1	0	0
FAT1	2195	broad.mit.edu	37	4	187539116	187539116	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr4:187539116A>G	uc003izf.2	-	10	8812	c.8624T>C	c.(8623-8625)CTT>CCT	p.L2875P		NM_005245	NP_005236	Q14517	FAT1_HUMAN	FAT tumor suppressor 1 precursor	2875	Extracellular (Potential).|Cadherin 26.				actin filament organization|anatomical structure morphogenesis|cell migration|cell-cell signaling|establishment or maintenance of cell polarity|homophilic cell adhesion	cell-cell junction|integral to plasma membrane|nucleus|perinuclear region of cytoplasm	calcium ion binding|protein binding			ovary(10)|central_nervous_system(1)|pancreas(1)	12						TTCATGGTCAAGTTCCTTTAA	0.418000										HNSCC(5;0.00058)			24	37					0	0	1	0	0
SLC6A19	340024	broad.mit.edu	37	5	1219640	1219640	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:1219640T>C	uc003jbw.3	+	10	1455	c.1399T>C	c.(1399-1401)TTC>CTC	p.F467L		NM_001003841	NP_001003841	Q695T7	S6A19_HUMAN	solute carrier family 6, member 19	467	Helical; Name=9; (Potential).				cellular nitrogen compound metabolic process	integral to plasma membrane	amino acid transmembrane transporter activity|neurotransmitter:sodium symporter activity				0	all_cancers(3;3.55e-15)|Lung NSC(6;2.89e-14)|all_lung(6;2.2e-13)|all_epithelial(6;3.75e-10)		Epithelial(17;0.000356)|all cancers(22;0.00137)|OV - Ovarian serous cystadenocarcinoma(19;0.00239)|Lung(60;0.185)			CCTGGGGACATTCCTCATTGG	0.627000													20	27					0	0	1	0	0
TRIO	7204	broad.mit.edu	37	5	14497016	14497016	+	Missense_Mutation	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:14497016C>A	uc003jff.2	+	50	7915	c.7909C>A	c.(7909-7911)CGT>AGT	p.R2637S	TRIO_uc003jfg.2_RNA	NM_007118	NP_009049	O75962	TRIO_HUMAN	triple functional domain (PTPRF interacting)	2637					apoptosis|axon guidance|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|transmembrane receptor protein tyrosine phosphatase signaling pathway	cytosol	ATP binding|protein serine/threonine kinase activity|Rho guanyl-nucleotide exchange factor activity			skin(4)|central_nervous_system(3)|ovary(3)|large_intestine(2)|stomach(2)|breast(2)|upper_aerodigestive_tract(1)|kidney(1)	18	Lung NSC(4;0.000742)					CACAGCACTCCGTTTAAGGAA	0.448000													29	39					5.60225e-13	6.01075e-13	1	1	0
BASP1	10409	broad.mit.edu	37	5	17275784	17275784	+	Silent	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:17275784G>A	uc003jfx.2	+	2	638	c.459G>A	c.(457-459)GCG>GCA	p.A153A		NM_006317	NP_006308	P80723	BASP1_HUMAN	brain abundant, membrane attached signal protein	153					glomerular visceral epithelial cell differentiation|negative regulation of transcription, DNA-dependent	cytoplasm|cytoskeleton|growth cone|nuclear speck|plasma membrane	protein domain specific binding|transcription corepressor activity|transcription regulatory region DNA binding				0						AGACTGAGGCGCCCGCAGCTC	0.488000													5	7					0	0	1	0	0
POLK	51426	broad.mit.edu	37	5	74892358	74892358	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:74892358G>C	uc003kdw.2	+	13	1936	c.1840G>C	c.(1840-1842)GAG>CAG	p.E614Q	POLK_uc003kdx.2_RNA|POLK_uc003kdy.2_RNA|POLK_uc010izq.2_Missense_Mutation_p.E416Q|POLK_uc003kec.2_Missense_Mutation_p.E524Q|POLK_uc010izr.2_RNA|POLK_uc010izs.2_RNA|POLK_uc003ked.2_Intron|POLK_uc003kee.2_Intron|POLK_uc003kef.2_Missense_Mutation_p.E524Q	NM_016218	NP_057302	Q9UBT6	POLK_HUMAN	DNA-directed DNA polymerase kappa	614					DNA replication|nucleotide-excision repair, DNA gap filling	nucleus	damaged DNA binding|DNA-directed DNA polymerase activity|metal ion binding			ovary(2)|kidney(2)	4		all_lung(232;0.0131)|Lung NSC(167;0.0282)|Ovarian(174;0.0798)|Prostate(461;0.184)		OV - Ovarian serous cystadenocarcinoma(47;2.9e-54)|all cancers(79;1.27e-42)		GGAAATATCAGAGAATTCAGA	0.368000								DNA_polymerases_(catalytic_subunits)|Direct_reversal_of_damage					69	81					0	0	1	0	0
BHMT	635	broad.mit.edu	37	5	78426847	78426847	+	Missense_Mutation	SNP	A	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:78426847A>G	uc003kfu.3	+	8	1234	c.1129A>G	c.(1129-1131)AAA>GAA	p.K377E	BHMT_uc011cti.1_Missense_Mutation_p.K224E	NM_001713	NP_001704	Q93088	BHMT1_HUMAN	betaine-homocysteine methyltransferase	377					protein methylation|regulation of homocysteine metabolic process	cytoplasm	betaine-homocysteine S-methyltransferase activity|homocysteine S-methyltransferase activity|zinc ion binding			ovary(1)	1		all_lung(232;0.00051)|Lung NSC(167;0.00131)|Ovarian(174;0.0261)|Prostate(461;0.191)		OV - Ovarian serous cystadenocarcinoma(54;1.88e-45)|Epithelial(54;8.07e-41)|all cancers(79;3.51e-36)	L-Methionine(DB00134)	GGGAGTGACCAAAGGAACAGC	0.493000													50	101					0	0	1	0	0
MSH3	4437	broad.mit.edu	37	5	80040402	80040402	+	Silent	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:80040402G>A	uc003kgz.2	+	12	1984	c.1731G>A	c.(1729-1731)AAG>AAA	p.K577K		NM_002439	NP_002430	P20585	MSH3_HUMAN	mutS homolog 3	577					maintenance of DNA repeat elements|meiotic mismatch repair|negative regulation of DNA recombination|positive regulation of helicase activity|reciprocal meiotic recombination|somatic recombination of immunoglobulin gene segments	MutSbeta complex|nuclear chromosome	ATP binding|DNA-dependent ATPase activity|double-strand/single-strand DNA junction binding|enzyme binding|loop DNA binding|Y-form DNA binding	p.K577T(1)		lung(2)|ovary(1)|breast(1)	4		Lung NSC(167;0.00479)|all_lung(232;0.00507)|Ovarian(174;0.0261)|Breast(144;0.244)		OV - Ovarian serous cystadenocarcinoma(54;2.38e-45)|Epithelial(54;1.58e-38)|all cancers(79;4.93e-33)		GGAAGTTAAAGAAGTGGGTGA	0.338000								MMR					20	28					0	0	1	0	0
SOX30	11063	broad.mit.edu	37	5	157075894	157075894	+	Missense_Mutation	SNP	A	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:157075894A>T	uc003lxb.1	-	2	1320	c.978T>A	c.(976-978)GAT>GAA	p.D326E	SOX30_uc003lxc.1_Missense_Mutation_p.D326E|SOX30_uc011dds.1_Missense_Mutation_p.D21E	NM_178424	NP_848511	O94993	SOX30_HUMAN	SRY (sex determining region Y)-box 30 isoform a	326					regulation of transcription from RNA polymerase II promoter|regulation of transcription, DNA-dependent|response to corticosteroid stimulus|transcription, DNA-dependent	nucleus|nucleus	sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity			ovary(1)|central_nervous_system(1)	2	Renal(175;0.00488)	Medulloblastoma(196;0.0354)|all_neural(177;0.138)	Kidney(164;0.000171)|KIRC - Kidney renal clear cell carcinoma(164;0.000785)			TGAAGGGAGTATCTGGTATGC	0.428000													34	55					0	0	1	0	0
NHP2	55651	broad.mit.edu	37	5	177580732	177580732	+	Silent	SNP	G	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:177580732G>T	uc003mir.2	-	1	230	c.87C>A	c.(85-87)GTC>GTA	p.V29V	NHP2_uc003mis.2_Silent_p.V29V	NM_017838	NP_060308	Q9NX24	NHP2_HUMAN	nucleolar protein family A, member 2 isoform a	29					rRNA pseudouridine synthesis	Cajal body|nucleolus|small nucleolar ribonucleoprotein complex	protein binding|snoRNA binding				0						GGTTCTGGTTGACCAGCAGCT	0.662000													20	18					8.28177e-16	9.07471e-16	1	1	0
MAML1	9794	broad.mit.edu	37	5	179193185	179193185	+	Nonsense_Mutation	SNP	G	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:179193185G>T	uc003mkm.2	+	2	1437	c.1174G>T	c.(1174-1176)GAG>TAG	p.E392*	MAML1_uc003mkn.1_Nonsense_Mutation_p.E392*	NM_014757	NP_055572	Q92585	MAML1_HUMAN	mastermind-like 1	392					Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear speck	peptide antigen binding|protein kinase binding|transcription coactivator activity			lung(4)|ovary(2)	6	all_cancers(89;0.000197)|all_epithelial(37;6.7e-05)|Renal(175;0.000159)|Lung NSC(126;0.00121)|all_lung(126;0.00218)	all_cancers(40;0.0308)|Medulloblastoma(196;0.00498)|all_neural(177;0.0138)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			AGGGGCCTCAGAGCTGTCCTC	0.657000													23	68					2.32416e-17	2.60205e-17	1	1	0
TBC1D9B	23061	broad.mit.edu	37	5	179320371	179320371	+	Missense_Mutation	SNP	T	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:179320371T>A	uc003mlh.2	-	5	711	c.674A>T	c.(673-675)GAG>GTG	p.E225V	TBC1D9B_uc003mli.2_Missense_Mutation_p.E225V|TBC1D9B_uc003mlj.2_Missense_Mutation_p.E225V	NM_198868	NP_942568	Q66K14	TBC9B_HUMAN	TBC1 domain family, member 9B (with GRAM domain)	225						integral to membrane|intracellular	calcium ion binding|Rab GTPase activator activity			breast(1)|skin(1)	2	all_cancers(89;0.000197)|all_epithelial(37;6.84e-05)|Renal(175;0.000159)|Lung NSC(126;0.00136)|all_lung(126;0.00243)	all_cancers(40;0.0236)|Medulloblastoma(196;0.00498)|all_neural(177;0.0138)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			GAAGAAGAGCTCCTGGTCGCG	0.607000													23	36					0	0	1	0	0
TBC1D7	51256	broad.mit.edu	37	6	13307966	13307966	+	Missense_Mutation	SNP	A	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr6:13307966A>C	uc003naj.2	-	6	622	c.531T>G	c.(529-531)TTT>TTG	p.F177L	TBC1D7_uc011dis.1_Intron|TBC1D7_uc003nan.2_Missense_Mutation_p.F177L|TBC1D7_uc003nal.2_Missense_Mutation_p.F177L|TBC1D7_uc003nam.2_Missense_Mutation_p.F177L|TBC1D7_uc003nao.2_Missense_Mutation_p.F150L|TBC1D7_uc010jpd.2_Missense_Mutation_p.F131L|TBC1D7_uc003nap.2_Missense_Mutation_p.F150L	NM_016495	NP_057579	Q9P0N9	TBCD7_HUMAN	TBC1 domain family, member 7 isoform a	177	Rab-GAP TBC.				positive regulation of protein ubiquitination	cytoplasmic membrane-bounded vesicle	protein binding|Rab GTPase activator activity			ovary(1)	1	Breast(50;0.0296)|Ovarian(93;0.0339)	all_hematologic(90;0.135)	Epithelial(50;0.0784)|BRCA - Breast invasive adenocarcinoma(129;0.13)|all cancers(50;0.21)			AGTATTGTTCAAACGCTTTTG	0.398000													21	52					0	0	1	0	0
AHI1	54806	broad.mit.edu	37	6	135644423	135644423	+	Nonsense_Mutation	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr6:135644423C>A	uc003qgi.2	-	25	3589	c.3205G>T	c.(3205-3207)GAA>TAA	p.E1069*	AHI1_uc003qgf.2_RNA|AHI1_uc003qgg.2_Nonsense_Mutation_p.E519*|AHI1_uc003qgh.2_Nonsense_Mutation_p.E1069*|AHI1_uc003qgj.2_Nonsense_Mutation_p.E1069*|AHI1_uc003qgk.3_Intron	NM_001134831	NP_001128303	Q8N157	AHI1_HUMAN	Abelson helper integration site 1 isoform a	1069	SH3.					adherens junction|cilium|microtubule basal body				ovary(1)|kidney(1)|central_nervous_system(1)	3	Breast(56;0.239)|Colorectal(23;0.24)			GBM - Glioblastoma multiforme(68;0.00904)|OV - Ovarian serous cystadenocarcinoma(155;0.00991)		ATGGTTAGTTCATCTGATCGA	0.438000													12	14					0.00010058	0.000102572	1	1	0
REPS1	85021	broad.mit.edu	37	6	139251190	139251190	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr6:139251190G>C	uc003qii.2	-	9	1760	c.1181C>G	c.(1180-1182)GCT>GGT	p.A394G	REPS1_uc003qig.3_Missense_Mutation_p.A394G|REPS1_uc011edr.1_Missense_Mutation_p.A394G|REPS1_uc003qij.2_Missense_Mutation_p.A394G|REPS1_uc003qik.2_Missense_Mutation_p.A27G	NM_031922	NP_114128	Q96D71	REPS1_HUMAN	RALBP1 associated Eps domain containing 1	394						coated pit|plasma membrane	calcium ion binding|SH3 domain binding			lung(1)|breast(1)	2				GBM - Glioblastoma multiforme(68;0.000434)|OV - Ovarian serous cystadenocarcinoma(155;0.000548)		AGGAGCTTCAGCAGGAGAGCC	0.418000													45	51					0	0	1	0	0
HOXA3	3200	broad.mit.edu	37	7	27147884	27147884	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr7:27147884G>A	uc011jzl.1	-	3	1182	c.982C>T	c.(982-984)CGC>TGC	p.R328C	HOXA3_uc011jzk.1_Missense_Mutation_p.R170C|HOXA3_uc003syk.2_Missense_Mutation_p.R328C	NM_030661	NP_109377	O43365	HXA3_HUMAN	homeobox A3 isoform a	328					angiogenesis	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(2)	2						GCCGTGTAGCGCTTCTGTGGG	0.726000													5	11					0	0	1	0	0
ABCA13	154664	broad.mit.edu	37	7	48411809	48411809	+	Silent	SNP	C	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr7:48411809C>A	uc003toq.2	+	33	10873	c.10848C>A	c.(10846-10848)GCC>GCA	p.A3616A	ABCA13_uc010kys.1_Silent_p.A690A|ABCA13_uc003tos.1_Silent_p.A442A	NM_152701	NP_689914	Q86UQ4	ABCAD_HUMAN	ATP binding cassette, sub-family A (ABC1),	3616	Helical; (Potential).				transport	integral to membrane	ATP binding|ATPase activity			ovary(5)|central_nervous_system(4)|skin(1)	10						ATTTCCTGGCCTGGTTCCTGG	0.463000													29	47					4.59853e-10	4.88297e-10	1	1	0
TMEM139	135932	broad.mit.edu	37	7	142983611	142983611	+	Missense_Mutation	SNP	T	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr7:142983611T>C	uc010lov.2	+	4	479	c.340T>C	c.(340-342)TAC>CAC	p.Y114H	CASP2_uc003wco.2_5'Flank|CASP2_uc003wcp.2_5'Flank|CASP2_uc011kta.1_5'Flank|TMEM139_uc003wck.3_Missense_Mutation_p.Y114H|TMEM139_uc003wcl.2_Missense_Mutation_p.Y114H|TMEM139_uc003wcm.2_Missense_Mutation_p.Y114H|TMEM139_uc003wcn.2_RNA	NM_153345	NP_699176	Q8IV31	TM139_HUMAN	transmembrane protein 139 precursor	114	Cytoplasmic (Potential).					integral to membrane					0	Melanoma(164;0.059)					ACCACCCCCCTACAGCACTGT	0.577000													41	88					0	0	1	0	0
CA8	767	broad.mit.edu	37	8	61192348	61192348	+	Silent	SNP	C	T	T			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr8:61192348C>T	uc003xtz.1	-	2	440	c.192G>A	c.(190-192)TCG>TCA	p.S64S	CA8_uc003xua.1_Silent_p.S64S|CA8_uc003xub.2_Silent_p.S64S	NM_004056	NP_004047	P35219	CAH8_HUMAN	carbonic anhydrase VIII	64					one-carbon metabolic process		carbonate dehydratase activity|zinc ion binding				0		all_cancers(86;0.172)|all_epithelial(80;0.0383)|all_lung(136;0.0413)|Lung NSC(129;0.0474)				CATCCAACAGCGAGGGGTCAT	0.473000													61	33					0	0	1	0	0
C9orf5	23731	broad.mit.edu	37	9	111853340	111853340	+	Nonsense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr9:111853340G>A	uc004bdt.3	-	5	1044	c.1012C>T	c.(1012-1014)CGA>TGA	p.R338*	C9orf5_uc004bds.3_RNA|C9orf5_uc004bdr.3_Nonsense_Mutation_p.R338*	NM_032012	NP_114401	Q9H330	CI005_HUMAN	hypothetical protein LOC23731	338						integral to membrane				central_nervous_system(1)	1		Myeloproliferative disorder(63;0.204)		OV - Ovarian serous cystadenocarcinoma(323;3.08e-05)|STAD - Stomach adenocarcinoma(157;0.0823)		TCAGGCCTTCGTCTGCCCAGA	0.502000													13	60					0	0	1	0	0
C9orf171	389799	broad.mit.edu	37	9	135447853	135447853	+	Missense_Mutation	SNP	G	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr9:135447853G>A	uc004cbn.2	+	7	967	c.919G>A	c.(919-921)GTG>ATG	p.V307M	C9orf171_uc004cbo.2_Missense_Mutation_p.V271M	NM_207417	NP_997300	Q6ZQR2	CI171_HUMAN	hypothetical protein LOC389799	307										ovary(4)|large_intestine(1)	5						AGAGTGTGCCGTGCGCCAGGG	0.602000													24	28					0	0	1	0	0
SNAPC4	6621	broad.mit.edu	37	9	139273027	139273027	+	Silent	SNP	C	G	G			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr9:139273027C>G	uc004chh.2	-	21	3261	c.3252G>C	c.(3250-3252)GGG>GGC	p.G1084G		NM_003086	NP_003077	Q5SXM2	SNPC4_HUMAN	small nuclear RNA activating complex,	1084	Pro-rich.				snRNA transcription from RNA polymerase II promoter|snRNA transcription from RNA polymerase III promoter	snRNA-activating protein complex	DNA binding|sequence-specific DNA binding transcription factor activity				0		Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;5.31e-06)|Epithelial(140;7.13e-06)		CAGGGAGAAGCCCCTGGGCTG	0.687000													3	10					0	0	1	0	0
ZFY	7544	broad.mit.edu	37	Y	2843189	2843189	+	Missense_Mutation	SNP	G	C	C			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chrY:2843189G>C	uc004fqj.2	+	4	1009	c.688G>C	c.(688-690)GCA>CCA	p.A230P	ZFY_uc010nwd.1_Missense_Mutation_p.A230P|ZFY_uc011nan.1_Missense_Mutation_p.A39P|ZFY_uc010nwe.2_Missense_Mutation_p.A204P	NM_003411	NP_003402	P08048	ZFY_HUMAN	zinc finger protein, Y-linked isoform 1	230					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0						GACCATCGATGCAGAATCAGA	0.398000													2	9					0	0	1	0	0
OR2M2	391194	broad.mit.edu	37	1	248344277	248344277	+	Frame_Shift_Del	DEL	A	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr1:248344277delA	uc010pzf.1	+	1	990	c.990delA	c.(988-990)ATAfs	p.I330fs		NM_001004688	NP_001004688	Q96R28	OR2M2_HUMAN	olfactory receptor, family 2, subfamily M,	330	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(3)|skin(1)	4	all_cancers(71;0.000149)|all_epithelial(71;1.27e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0245)			TCTTTCTAATATCCATCTTTT	0.318													49	117	---	---	---	---					
ITFG1	81533	broad.mit.edu	37	16	47189669	47189669	+	Frame_Shift_Del	DEL	T	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr16:47189669delT	uc002eet.2	-	18	1862	c.1800delA	c.(1798-1800)AAAfs	p.K600fs	ITFG1_uc010vgg.1_Frame_Shift_Del_p.K345fs|ITFG1_uc010vgh.1_3'UTR	NM_030790	NP_110417	Q8TB96	TIP_HUMAN	integrin alpha FG-GAP repeat containing 1	600						extracellular region|integral to membrane				ovary(1)|central_nervous_system(1)	2		all_cancers(37;0.0613)|all_lung(18;0.0543)|Lung NSC(13;0.227)				CTTCTTGTCGTTTTTCTCTAT	0.328													77	162	---	---	---	---					
FOXK2	3607	broad.mit.edu	37	17	80543893	80543893	+	Frame_Shift_Del	DEL	C	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr17:80543893delC	uc002kfn.2	+	7	1564	c.1393delC	c.(1393-1395)CCAfs	p.P465fs	FOXK2_uc002kfm.1_Frame_Shift_Del_p.P465fs|FOXK2_uc010diu.2_Intron	NM_004514	NP_004505	Q01167	FOXK2_HUMAN	forkhead box K2	465					embryo development|pattern specification process|regulation of sequence-specific DNA binding transcription factor activity|regulation of transcription from RNA polymerase II promoter|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|magnesium ion binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding				0	Breast(20;0.00106)|all_neural(118;0.0952)		OV - Ovarian serous cystadenocarcinoma(97;0.0371)|BRCA - Breast invasive adenocarcinoma(99;0.0415)			GACCTCCCAGCCACCCGTCGT	0.632													22	48	---	---	---	---					
ZNF814	730051	broad.mit.edu	37	19	58384658	58384660	+	In_Frame_Del	DEL	CTT	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr19:58384658_58384660delCTT	uc002qqo.2	-	3	2370_2372	c.2098_2100delAAG	c.(2098-2100)AAGdel	p.K700del	ZNF814_uc002qqk.2_Intron|ZNF814_uc010yhl.1_Intron	NM_001144989	NP_001138461	B7Z6K7	ZN814_HUMAN	zinc finger protein 814	700	C2H2-type 18.				regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding				0						GGAGGTGAGACTTCTTCTTAAAT	0.384													8	10	---	---	---	---					
DMXL1	1657	broad.mit.edu	37	5	118500212	118500213	+	Frame_Shift_Ins	INS	-	AGTCATTT	AGTCATTT			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr5:118500212_118500213insAGTCATTT	uc003ksd.2	+	20	4894_4895	c.4713_4714insAGTCATTT	c.(4711-4716)ACAAGTfs	p.T1571fs	DMXL1_uc010jcl.1_Frame_Shift_Ins_p.T1571fs	NM_005509	NP_005500	Q9Y485	DMXL1_HUMAN	Dmx-like 1	1571_1572										ovary(2)	2		all_cancers(142;0.0314)|all_epithelial(76;0.00559)|Prostate(80;0.11)|Breast(839;0.231)		OV - Ovarian serous cystadenocarcinoma(64;0.000563)|Epithelial(69;0.00179)|all cancers(49;0.0243)		GCCTGTCTACAAGTCATTTTGC	0.342													20	42	---	---	---	---					
ZNF292	23036	broad.mit.edu	37	6	87928395	87928395	+	Frame_Shift_Del	DEL	A	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr6:87928395delA	uc003plm.3	+	4	525	c.484delA	c.(484-486)AAAfs	p.K162fs	ZNF292_uc003pll.1_Frame_Shift_Del_p.K162fs	NM_015021	NP_055836	O60281	ZN292_HUMAN	zinc finger protein 292	162					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(4)	4		all_cancers(76;3.82e-09)|Prostate(29;1.34e-10)|Acute lymphoblastic leukemia(125;2.17e-10)|all_hematologic(105;1.08e-06)|all_epithelial(107;5.31e-05)		BRCA - Breast invasive adenocarcinoma(108;0.0199)		TGGGGTGTGGAAAAACCCGGT	0.368													7	8	---	---	---	---					
AIM1	202	broad.mit.edu	37	6	106968989	106968991	+	In_Frame_Del	DEL	TCT	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr6:106968989_106968991delTCT	uc003prh.2	+	2	3169_3171	c.2682_2684delTCT	c.(2680-2685)AATCTT>AAT	p.L896del		NM_001624	NP_001615	Q9Y4K1	AIM1_HUMAN	absent in melanoma 1	896							sugar binding			breast(4)|ovary(2)|upper_aerodigestive_tract(1)|large_intestine(1)|skin(1)	9	Breast(9;0.0138)|all_epithelial(6;0.169)	all_cancers(87;4.67e-25)|all_epithelial(87;5.46e-21)|Acute lymphoblastic leukemia(125;2.15e-07)|all_hematologic(75;5.28e-06)|Colorectal(196;3.46e-05)|all_lung(197;5.94e-05)|Lung NSC(302;7.26e-05)|Ovarian(999;0.00473)	Epithelial(6;0.00114)|all cancers(7;0.00726)|BRCA - Breast invasive adenocarcinoma(8;0.0114)|OV - Ovarian serous cystadenocarcinoma(5;0.0305)	all cancers(137;1.73e-50)|Epithelial(106;2.42e-48)|OV - Ovarian serous cystadenocarcinoma(136;1.51e-27)|BRCA - Breast invasive adenocarcinoma(108;0.00104)|GBM - Glioblastoma multiforme(226;0.00858)		AACAGTCAAATCTTCTGCCCGAC	0.463													55	93	---	---	---	---					
GPT	2875	broad.mit.edu	37	8	145732311	145732312	+	Frame_Shift_Ins	INS	-	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	5d320b5a-a67a-4a11-908d-9c5e8c70e16a	g.chr8:145732311_145732312insA	uc011lli.1	+	12	1576_1577	c.1419_1420insA	c.(1417-1422)CCCTTGfs	p.P473fs	GPT_uc003zdh.3_Frame_Shift_Ins_p.P473fs|MFSD3_uc003zdi.1_5'Flank	NM_005309	NP_005300	P24298	ALAT1_HUMAN	glutamic pyruvate transaminase	473_474					gluconeogenesis	cytosol	1-aminocyclopropane-1-carboxylate synthase activity|L-alanine:2-oxoglutarate aminotransferase activity|pyridoxal phosphate binding			ovary(1)|central_nervous_system(1)	2	all_cancers(97;5.56e-11)|all_epithelial(106;3.54e-10)|Lung NSC(106;5.7e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		OV - Ovarian serous cystadenocarcinoma(54;1.48e-41)|Epithelial(56;1.85e-40)|all cancers(56;3.59e-35)|BRCA - Breast invasive adenocarcinoma(115;0.0483)|Colorectal(110;0.055)		L-Alanine(DB00160)|L-Glutamic Acid(DB00142)|Pyridoxal Phosphate(DB00114)	TTCTGCCCCCCTTGGAGAAACT	0.629													36	73	---	---	---	---					
OR2M2	391194	broad.mit.edu	37	1	248344277	248344277	+	Frame_Shift_Del	DEL	A	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr1:248344277delA	uc010pzf.1	+	1	990	c.990delA	c.(988-990)ATAfs	p.I330fs		NM_001004688	NP_001004688	Q96R28	OR2M2_HUMAN	olfactory receptor, family 2, subfamily M,	330	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(3)|skin(1)	4	all_cancers(71;0.000149)|all_epithelial(71;1.27e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0245)			TCTTTCTAATATCCATCTTTT	0.318													49	117	---	---	---	---					
FOXK2	3607	broad.mit.edu	37	17	80543893	80543893	+	Frame_Shift_Del	DEL	C	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr17:80543893delC	uc002kfn.2	+	7	1564	c.1393delC	c.(1393-1395)CCAfs	p.P465fs	FOXK2_uc002kfm.1_Frame_Shift_Del_p.P465fs|FOXK2_uc010diu.2_Intron	NM_004514	NP_004505	Q01167	FOXK2_HUMAN	forkhead box K2	465					embryo development|pattern specification process|regulation of sequence-specific DNA binding transcription factor activity|regulation of transcription from RNA polymerase II promoter|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|magnesium ion binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding				0	Breast(20;0.00106)|all_neural(118;0.0952)		OV - Ovarian serous cystadenocarcinoma(97;0.0371)|BRCA - Breast invasive adenocarcinoma(99;0.0415)			GACCTCCCAGCCACCCGTCGT	0.632													22	48	---	---	---	---					
ZNF814	730051	broad.mit.edu	37	19	58384658	58384660	+	In_Frame_Del	DEL	CTT	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr19:58384658_58384660delCTT	uc002qqo.2	-	3	2370_2372	c.2098_2100delAAG	c.(2098-2100)AAGdel	p.K700del	ZNF814_uc002qqk.2_Intron|ZNF814_uc010yhl.1_Intron	NM_001144989	NP_001138461	B7Z6K7	ZN814_HUMAN	zinc finger protein 814	700	C2H2-type 18.				regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding				0						GGAGGTGAGACTTCTTCTTAAAT	0.384													8	10	---	---	---	---					
ANKRD36	375248	broad.mit.edu	37	2	97808574	97808575	+	Splice_Site	INS	-	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr2:97808574_97808575insA	uc010yva.1	+	8	1145	c.901_splice	c.e8+2	p.V301_splice	ANKRD36_uc010yuz.1_Splice_Site|ANKRD36_uc010fic.2_Intron|ANKRD36_uc002sxo.2_Intron|ANKRD36_uc002sxp.3_Splice_Site	NM_001164315	NP_001157787	A6QL64	AN36A_HUMAN	ankyrin repeat domain 36												0						CTGGGACAGGTATTTTGGAATA	0.302													8	4	---	---	---	---					
DMXL1	1657	broad.mit.edu	37	5	118500212	118500213	+	Frame_Shift_Ins	INS	-	AGTCATTT	AGTCATTT			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr5:118500212_118500213insAGTCATTT	uc003ksd.2	+	20	4894_4895	c.4713_4714insAGTCATTT	c.(4711-4716)ACAAGTfs	p.T1571fs	DMXL1_uc010jcl.1_Frame_Shift_Ins_p.T1571fs	NM_005509	NP_005500	Q9Y485	DMXL1_HUMAN	Dmx-like 1	1571_1572										ovary(2)	2		all_cancers(142;0.0314)|all_epithelial(76;0.00559)|Prostate(80;0.11)|Breast(839;0.231)		OV - Ovarian serous cystadenocarcinoma(64;0.000563)|Epithelial(69;0.00179)|all cancers(49;0.0243)		GCCTGTCTACAAGTCATTTTGC	0.342													20	42	---	---	---	---					
ZNF292	23036	broad.mit.edu	37	6	87928395	87928395	+	Frame_Shift_Del	DEL	A	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr6:87928395delA	uc003plm.3	+	4	525	c.484delA	c.(484-486)AAAfs	p.K162fs	ZNF292_uc003pll.1_Frame_Shift_Del_p.K162fs	NM_015021	NP_055836	O60281	ZN292_HUMAN	zinc finger protein 292	162					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(4)	4		all_cancers(76;3.82e-09)|Prostate(29;1.34e-10)|Acute lymphoblastic leukemia(125;2.17e-10)|all_hematologic(105;1.08e-06)|all_epithelial(107;5.31e-05)		BRCA - Breast invasive adenocarcinoma(108;0.0199)		TGGGGTGTGGAAAAACCCGGT	0.368													7	8	---	---	---	---					
AIM1	202	broad.mit.edu	37	6	106968989	106968991	+	In_Frame_Del	DEL	TCT	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr6:106968989_106968991delTCT	uc003prh.2	+	2	3169_3171	c.2682_2684delTCT	c.(2680-2685)AATCTT>AAT	p.L896del		NM_001624	NP_001615	Q9Y4K1	AIM1_HUMAN	absent in melanoma 1	896							sugar binding			breast(4)|ovary(2)|upper_aerodigestive_tract(1)|large_intestine(1)|skin(1)	9	Breast(9;0.0138)|all_epithelial(6;0.169)	all_cancers(87;4.67e-25)|all_epithelial(87;5.46e-21)|Acute lymphoblastic leukemia(125;2.15e-07)|all_hematologic(75;5.28e-06)|Colorectal(196;3.46e-05)|all_lung(197;5.94e-05)|Lung NSC(302;7.26e-05)|Ovarian(999;0.00473)	Epithelial(6;0.00114)|all cancers(7;0.00726)|BRCA - Breast invasive adenocarcinoma(8;0.0114)|OV - Ovarian serous cystadenocarcinoma(5;0.0305)	all cancers(137;1.73e-50)|Epithelial(106;2.42e-48)|OV - Ovarian serous cystadenocarcinoma(136;1.51e-27)|BRCA - Breast invasive adenocarcinoma(108;0.00104)|GBM - Glioblastoma multiforme(226;0.00858)		AACAGTCAAATCTTCTGCCCGAC	0.463													55	93	---	---	---	---					
GPT	2875	broad.mit.edu	37	8	145732311	145732312	+	Frame_Shift_Ins	INS	-	A	A			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chr8:145732311_145732312insA	uc011lli.1	+	12	1576_1577	c.1419_1420insA	c.(1417-1422)CCCTTGfs	p.P473fs	GPT_uc003zdh.3_Frame_Shift_Ins_p.P473fs|MFSD3_uc003zdi.1_5'Flank	NM_005309	NP_005300	P24298	ALAT1_HUMAN	glutamic pyruvate transaminase	473_474					gluconeogenesis	cytosol	1-aminocyclopropane-1-carboxylate synthase activity|L-alanine:2-oxoglutarate aminotransferase activity|pyridoxal phosphate binding			ovary(1)|central_nervous_system(1)	2	all_cancers(97;5.56e-11)|all_epithelial(106;3.54e-10)|Lung NSC(106;5.7e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		OV - Ovarian serous cystadenocarcinoma(54;1.48e-41)|Epithelial(56;1.85e-40)|all cancers(56;3.59e-35)|BRCA - Breast invasive adenocarcinoma(115;0.0483)|Colorectal(110;0.055)		L-Alanine(DB00160)|L-Glutamic Acid(DB00142)|Pyridoxal Phosphate(DB00114)	TTCTGCCCCCCTTGGAGAAACT	0.629													36	73	---	---	---	---					
Unknown	0	broad.mit.edu	37	M	11032	11032	+	RNA	DEL	A	-	-			TCGA-IZ-8195-01A-31D-2396-08	TCGA-IZ-8195-11A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	fcdb724c-08ad-42b7-9fef-e4d84edaf2fe	34ef600a-d0cc-4306-ac0f-aa096e55c63d	g.chrM:11032delA	uc004cov.3	+	1		c.455delA			uc004cow.1_5'Flank|uc004cox.3_5'Flank					Homo sapiens potential LAG1 interactor mRNA, partial cds.																		CCACTATCACGAAAAAAACTC	0.423													8	4	---	---	---	---					
