Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MTMR11	10903	broad.mit.edu	37	1	149902758	149902758	+	Missense_Mutation	SNP	C	A	A			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr1:149902758C>A	uc001etl.3	-	14	1641	c.1390G>T	c.(1390-1392)GAC>TAC	p.D464Y	SF3B4_uc001etk.1_5'Flank|SF3B4_uc009wll.1_5'Flank|MTMR11_uc001etm.1_Missense_Mutation_p.D392Y|MTMR11_uc010pbm.1_3'UTR|MTMR11_uc010pbn.1_3'UTR	NM_001145862	NP_001139334	A4FU01	MTMRB_HUMAN	myotubularin related protein 11 isoform a	464	Myotubularin phosphatase.						phosphatase activity			central_nervous_system(1)	1	Breast(34;0.0009)|Ovarian(49;0.0377)|all_hematologic(923;0.0597)|Hepatocellular(266;0.161)|Colorectal(459;0.171)		LUSC - Lung squamous cell carcinoma(543;0.221)|STAD - Stomach adenocarcinoma(528;0.247)			CTGACACTGTCATGAAGAGCA	0.502000													16	36	---	---	---	---	6.31663e-08	1.05277e-07	0.003163	1	0
OR10Z1	128368	broad.mit.edu	37	1	158576561	158576561	+	Silent	SNP	C	T	T			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr1:158576561C>T	uc010pio.1	+	1	333	c.333C>T	c.(331-333)AAC>AAT	p.N111N		NM_001004478	NP_001004478	Q8NGY1	O10Z1_HUMAN	olfactory receptor, family 10, subfamily Z,	111	Helical; Name=3; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			pancreas(1)|skin(1)	2	all_hematologic(112;0.0378)					CCTGTACTAACTGCTTCCTTC	0.567000													6	222	---	---	---	---	0	0	0.001168	0	0
OR2M3	127062	broad.mit.edu	37	1	248366655	248366655	+	Missense_Mutation	SNP	G	T	T			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr1:248366655G>T	uc010pzg.1	+	1	286	c.286G>T	c.(286-288)GGT>TGT	p.G96C		NM_001004689	NP_001004689	Q8NG83	OR2M3_HUMAN	olfactory receptor, family 2, subfamily M,	96	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|skin(1)	2	all_cancers(71;0.000149)|all_epithelial(71;1.27e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0245)			TTCTATGGCTGGTTGTGCCAC	0.502000													129	310	---	---	---	---	4.83686e-69	8.91001e-69	0.003610	1	0
PLXDC2	84898	broad.mit.edu	37	10	20506361	20506361	+	Missense_Mutation	SNP	G	C	C			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr10:20506361G>C	uc001iqg.1	+	11	1766	c.1129G>C	c.(1129-1131)GAG>CAG	p.E377Q	PLXDC2_uc001iqh.1_Missense_Mutation_p.E328Q|PLXDC2_uc009xkc.1_RNA	NM_032812	NP_116201	Q6UX71	PXDC2_HUMAN	plexin domain containing 2 precursor	377	Extracellular (Potential).					integral to membrane				ovary(2)|central_nervous_system(1)|skin(1)	4						CTAGTCAAAAGAGAAGATGTG	0.418000													3	58	---	---	---	---	0	0	0.004672	0	0
PARD3	56288	broad.mit.edu	37	10	34985316	34985316	+	Missense_Mutation	SNP	A	C	C			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr10:34985316A>C	uc010qej.1	-	2	152	c.152T>G	c.(151-153)TTG>TGG	p.L51W	PARD3_uc010qek.1_Missense_Mutation_p.L51W|PARD3_uc010qel.1_Missense_Mutation_p.L51W|PARD3_uc010qem.1_Missense_Mutation_p.L51W|PARD3_uc010qen.1_Missense_Mutation_p.L51W|PARD3_uc010qeo.1_Missense_Mutation_p.L51W|PARD3_uc010qep.1_Missense_Mutation_p.L51W|PARD3_uc010qeq.1_Missense_Mutation_p.L51W|PARD3_uc001ixq.1_Missense_Mutation_p.L51W|PARD3_uc001ixr.1_Missense_Mutation_p.L51W|PARD3_uc001ixu.1_Missense_Mutation_p.L51W	NM_019619	NP_062565	Q8TEW0	PARD3_HUMAN	partitioning-defective protein 3 homolog	51					activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|asymmetric cell division|axonogenesis|cell cycle|establishment of epithelial cell polarity|protein complex assembly|protein targeting to membrane|tight junction assembly	cell cortex|cytoskeleton|cytosol|endomembrane system|tight junction	phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-3-phosphate binding|phosphatidylinositol-4,5-bisphosphate binding|protein binding			ovary(1)	1		Breast(68;0.0707)				TCCATGTTCCAAGCGATGCAC	0.413000													38	239	---	---	---	---	0	0	0.004878	0	0
SPI1	6688	broad.mit.edu	37	11	47380480	47380480	+	Silent	SNP	G	A	A			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr11:47380480G>A	uc001nfc.1	-	4	631	c.408C>T	c.(406-408)GGC>GGT	p.G136G	SPI1_uc001nfb.1_Silent_p.G137G|SLC39A13_uc001nfd.2_Intron|SPI1_uc009ylp.1_Silent_p.G130G	NM_003120	NP_003111	P17947	SPI1_HUMAN	hematopoietic transcription factor PU.1 isoform	136					negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|regulation of erythrocyte differentiation	nucleus	protein binding|RNA binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			lung(1)|central_nervous_system(1)	2				Lung(87;0.0967)		TCTGCCGCTCGCCCTCCTCCT	0.706000													3	1	---	---	---	---	0	0	0.004672	0	0
AHNAK	79026	broad.mit.edu	37	11	62287957	62287957	+	Silent	SNP	T	C	C			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr11:62287957T>C	uc001ntl.2	-	5	14232	c.13932A>G	c.(13930-13932)CAA>CAG	p.Q4644Q	AHNAK_uc001ntk.1_Intron	NM_001620	NP_001611	Q09666	AHNK_HUMAN	AHNAK nucleoprotein isoform 1	4644				Q -> H (in Ref. 2; AAA69898).	nervous system development	nucleus	protein binding			ovary(10)|pancreas(4)|skin(4)|upper_aerodigestive_tract(1)	19		Melanoma(852;0.155)				AGTCTGGGCCTTGAACGTCCA	0.537000													5	306	---	---	---	---	0	0	0.001168	0	0
ATG16L2	89849	broad.mit.edu	37	11	72537766	72537766	+	Missense_Mutation	SNP	A	G	G			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr11:72537766A>G	uc001otd.2	+	13	1304	c.1264A>G	c.(1264-1266)AAG>GAG	p.K422E	ATG16L2_uc001ote.2_Missense_Mutation_p.K316E|ATG16L2_uc009ytj.1_Intron|ATG16L2_uc001otf.2_Missense_Mutation_p.K177E|ATG16L2_uc001otg.2_Missense_Mutation_p.K156E|ATG16L2_uc009ytk.2_Missense_Mutation_p.K177E	NM_033388	NP_203746	Q8NAA4	A16L2_HUMAN	ATG16 autophagy related 16-like 2	422	WD 3.				autophagy|protein transport	cytoplasm	protein binding				0			BRCA - Breast invasive adenocarcinoma(5;2.73e-06)			GTCTGGACACAAGGATAAGGT	0.587000													3	136	---	---	---	---	0	0	0.004672	0	0
NF1	4763	broad.mit.edu	37	17	29508804	29508804	+	Splice_Site	SNP	G	T	T			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr17:29508804G>T	uc002hgg.2	+	7	1063	c.730_splice	c.e7+1	p.E244_splice	NF1_uc002hge.1_Splice_Site_p.E244_splice|NF1_uc002hgf.1_Splice_Site_p.E244_splice|NF1_uc002hgh.2_Splice_Site_p.E244_splice|NF1_uc010csn.1_Splice_Site_p.E104_splice	NM_001042492	NP_001035957	P21359	NF1_HUMAN	neurofibromin isoform 1						actin cytoskeleton organization|adrenal gland development|artery morphogenesis|camera-type eye morphogenesis|cerebral cortex development|collagen fibril organization|forebrain astrocyte development|forebrain morphogenesis|heart development|liver development|MAPKKK cascade|metanephros development|myelination in peripheral nervous system|negative regulation of cell migration|negative regulation of endothelial cell proliferation|negative regulation of MAP kinase activity|negative regulation of MAPKKK cascade|negative regulation of neuroblast proliferation|negative regulation of oligodendrocyte differentiation|negative regulation of transcription factor import into nucleus|osteoblast differentiation|phosphatidylinositol 3-kinase cascade|pigmentation|positive regulation of adenylate cyclase activity|positive regulation of neuron apoptosis|Ras protein signal transduction|regulation of blood vessel endothelial cell migration|regulation of bone resorption|response to hypoxia|smooth muscle tissue development|spinal cord development|sympathetic nervous system development|visual learning|wound healing	axon|cytoplasm|dendrite|intrinsic to internal side of plasma membrane|nucleus	protein binding|Ras GTPase activator activity			soft_tissue(159)|central_nervous_system(56)|lung(28)|large_intestine(27)|haematopoietic_and_lymphoid_tissue(18)|ovary(18)|autonomic_ganglia(12)|breast(3)|skin(3)|stomach(2)|thyroid(1)|prostate(1)|kidney(1)|pancreas(1)	330		all_cancers(10;1.29e-12)|all_epithelial(10;0.00347)|all_hematologic(16;0.00556)|Acute lymphoblastic leukemia(14;0.00593)|Breast(31;0.014)|Myeloproliferative disorder(56;0.0255)|all_lung(9;0.0321)|Lung NSC(157;0.0659)		UCEC - Uterine corpus endometrioid carcinoma (4;4.38e-05)|all cancers(4;1.64e-26)|Epithelial(4;9.15e-23)|OV - Ovarian serous cystadenocarcinoma(4;3.58e-21)|GBM - Glioblastoma multiforme(4;0.00146)		GATATGGCTGGTAAGGATACG	0.313000			D|Mis|N|F|S|O		neurofibroma|glioma	neurofibroma|glioma			Neurofibromatosis_type_1	TCGA GBM(6;<1E-08)|TSP Lung(7;0.0071)|TCGA Ovarian(3;0.0088)			19	67	---	---	---	---	6.94344e-10	1.2151e-09	0.006122	1	0
KIAA1632	57724	broad.mit.edu	37	18	43487997	43487997	+	Missense_Mutation	SNP	C	T	T			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr18:43487997C>T	uc002lbm.2	-	24	4355	c.4255G>A	c.(4255-4257)GGA>AGA	p.G1419R	KIAA1632_uc002lbo.1_Missense_Mutation_p.G1419R|KIAA1632_uc010xcq.1_5'UTR|KIAA1632_uc010xcr.1_RNA|KIAA1632_uc010xcs.1_RNA|KIAA1632_uc002lbn.2_Missense_Mutation_p.G294R	NM_020964	NP_066015	Q9HCE0	EPG5_HUMAN	hypothetical protein LOC57724	1419					autophagy						0						TAGGTATCTCCTTTTTGAAAA	0.313000													10	88	---	---	---	---	0	0	0.007413	0	0
ZNF556	80032	broad.mit.edu	37	19	2877358	2877358	+	Silent	SNP	T	C	C			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr19:2877358T>C	uc002lwp.1	+	4	489	c.402T>C	c.(400-402)CGT>CGC	p.R134R	ZNF556_uc002lwq.2_Silent_p.R133R	NM_024967	NP_079243	Q9HAH1	ZN556_HUMAN	zinc finger protein 556	134					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			skin(3)	3				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		ATTGTAATCGTCATCTGCGCA	0.418000													4	106	---	---	---	---	0	0	0.001168	0	0
DYRK1B	9149	broad.mit.edu	37	19	40316404	40316404	+	Missense_Mutation	SNP	G	A	A			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr19:40316404G>A	uc002omj.2	-	11	2121	c.1841C>T	c.(1840-1842)CCT>CTT	p.P614L	DYRK1B_uc002omi.2_Missense_Mutation_p.P586L|DYRK1B_uc002omk.2_Missense_Mutation_p.P574L	NM_004714	NP_004705	Q9Y463	DYR1B_HUMAN	dual-specificity tyrosine-(Y)-phosphorylation	614					positive regulation of transcription, DNA-dependent	nucleus	ATP binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|transcription coactivator activity			ovary(4)|stomach(1)|central_nervous_system(1)|skin(1)	7	all_cancers(60;5.79e-06)|all_lung(34;5.2e-08)|Lung NSC(34;6.14e-08)|Ovarian(47;0.06)		Epithelial(26;5.74e-25)|OV - Ovarian serous cystadenocarcinoma(5;3.13e-24)|all cancers(26;8.59e-23)			GCCCAGGTGAGGCCCCAGAGT	0.711000													2	0	---	---	---	---	0	0	0.004672	0	0
ZNF211	10520	broad.mit.edu	37	19	58152577	58152577	+	Missense_Mutation	SNP	A	G	G			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr19:58152577A>G	uc002qpq.2	+	3	903	c.723A>G	c.(721-723)ATA>ATG	p.I241M	ZNF211_uc010yhb.1_Missense_Mutation_p.I245M|ZNF211_uc002qpp.2_Missense_Mutation_p.I254M|ZNF211_uc002qpr.2_Missense_Mutation_p.I305M|ZNF211_uc002qps.2_Missense_Mutation_p.I306M|ZNF211_uc002qpt.2_Missense_Mutation_p.I253M|ZNF211_uc010yhc.1_Missense_Mutation_p.I253M|ZNF211_uc010yhd.1_Missense_Mutation_p.I180M|ZNF211_uc010yhe.1_Missense_Mutation_p.I232M	NM_198855	NP_942152	Q13398	ZN211_HUMAN	zinc finger protein 211 isoform 2	241						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			ovary(2)	2		Colorectal(82;5.46e-05)|all_neural(62;0.0218)|Breast(46;0.0389)|Ovarian(87;0.0443)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.026)		TTAGCCACATAGACACACTTG	0.448000													3	163	---	---	---	---	0	0	0.004672	0	0
RASSF2	9770	broad.mit.edu	37	20	4768882	4768882	+	Silent	SNP	G	A	A			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr20:4768882G>A	uc002wld.2	-	8	726	c.672C>T	c.(670-672)TAC>TAT	p.Y224Y	RASSF2_uc002wlc.2_RNA|RASSF2_uc002wle.2_RNA|RASSF2_uc002wlf.2_Silent_p.Y224Y|RASSF2_uc010gbh.2_5'Flank	NM_170774	NP_739580	P50749	RASF2_HUMAN	Ras association domain family 2	224	Ras-associating.				cell cycle|signal transduction	nucleus	protein binding			ovary(3)|lung(2)|large_intestine(1)	6						TATGGACCACGTACAAGGCAA	0.383000													4	132	---	---	---	---	0	0	0.000602	0	0
LOC220729	220729	broad.mit.edu	37	3	197348674	197348674	+	RNA	SNP	A	G	G	rs144273946	by1000genomes	TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr3:197348674A>G	uc011bug.1	-	4		c.417T>C			LOC220729_uc003fxw.2_RNA|LOC220729_uc003fxy.2_RNA|LOC220729_uc010iao.1_Intron					Homo sapiens cDNA FLJ60865 complete cds, highly similar to Succinate dehydrogenase (ubiquinone) flavoprotein subunit, mitochondrial precursor (EC 1.3.5.1).												0						GGCTCTGTCCACCAAATGCAC	0.478000													4	134	---	---	---	---	0	0	0.000602	0	0
GRIA2	2891	broad.mit.edu	37	4	158142278	158142278	+	Missense_Mutation	SNP	G	C	C			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr4:158142278G>C	uc003ipm.3	+	1	543	c.84G>C	c.(82-84)CAG>CAC	p.Q28H	GRIA2_uc011cit.1_Intron|GRIA2_uc003ipl.3_Missense_Mutation_p.Q28H|GRIA2_uc003ipk.3_Intron|GRIA2_uc010iqh.1_5'Flank	NM_001083619	NP_001077088	P42262	GRIA2_HUMAN	glutamate receptor, ionotropic, AMPA 2 isoform 2	28	Extracellular (Potential).				synaptic transmission	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|cell junction|endocytic vesicle membrane|endoplasmic reticulum membrane|postsynaptic membrane	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|extracellular-glutamate-gated ion channel activity|kainate selective glutamate receptor activity			central_nervous_system(3)|ovary(1)	4	all_hematologic(180;0.24)	Renal(120;0.0458)		COAD - Colon adenocarcinoma(41;0.0294)	L-Glutamic Acid(DB00142)	ACAGCATACAGATAGGTAGGT	0.358000													63	215	---	---	---	---	0	0	0.003610	0	0
HLA-J	3137	broad.mit.edu	37	6	29977342	29977342	+	Missense_Mutation	SNP	A	T	T	rs113017032		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr6:29977342A>T	uc003rtl.3	+	5	723	c.361A>T	c.(361-363)AGG>TGG	p.R121W	HLA-G_uc011dmb.1_3'UTR|NCRNA00171_uc011dme.1_Intron|HLA-J_uc003nou.3_RNA|HLA-J_uc003nov.3_RNA					Homo sapiens major histocompatibility complex, class I, J (pseudogene), mRNA (cDNA clone IMAGE:4694038).												0						TGGGACTGAGAGGCAAGATTT	0.438000													5	70	---	---	---	---	0	0	0.003080	0	0
ALDOB	229	broad.mit.edu	37	9	104192048	104192048	+	Missense_Mutation	SNP	C	T	T			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr9:104192048C>T	uc004bbk.2	-	3	395	c.313G>A	c.(313-315)GTG>ATG	p.V105M		NM_000035	NP_000026	P05062	ALDOB_HUMAN	aldolase B, fructose-bisphosphate	105					fructose 1,6-bisphosphate metabolic process|fructose catabolic process|gluconeogenesis|glycolysis|NADH oxidation|positive regulation of ATPase activity|vacuolar proton-transporting V-type ATPase complex assembly	centriolar satellite|cytosol	ATPase binding|cytoskeletal protein binding|fructose binding|fructose-bisphosphate aldolase activity|identical protein binding			skin(1)	1		Acute lymphoblastic leukemia(62;0.0559)				TTGATTCCCACCACGATCCCC	0.522000													93	254	---	---	---	---	0	0	0.003610	0	0
SNAPC4	6621	broad.mit.edu	37	9	139286500	139286500	+	Missense_Mutation	SNP	G	T	T			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr9:139286500G>T	uc004chh.2	-	9	878	c.869C>A	c.(868-870)CCC>CAC	p.P290H		NM_003086	NP_003077	Q5SXM2	SNPC4_HUMAN	small nuclear RNA activating complex,	290	HTH myb-type 1.				snRNA transcription from RNA polymerase II promoter|snRNA transcription from RNA polymerase III promoter	snRNA-activating protein complex	DNA binding|sequence-specific DNA binding transcription factor activity				0		Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;5.31e-06)|Epithelial(140;7.13e-06)		GTTGATGCTGGGGTGCTCCGA	0.627000													5	138	---	---	---	---	0.00116845	0.00177807	0.001168	1	0
FAM47A	158724	broad.mit.edu	37	X	34148199	34148199	+	Missense_Mutation	SNP	G	T	T			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chrX:34148199G>T	uc004ddg.2	-	1	2230	c.2197C>A	c.(2197-2199)CTT>ATT	p.L733I		NM_203408	NP_981953	Q5JRC9	FA47A_HUMAN	hypothetical protein LOC158724	733										ovary(4)|central_nervous_system(1)	5						GGTCCATAAAGATCGTCAAGA	0.428000													5	250	---	---	---	---	0.00116845	0.00177807	0.001168	1	0
CTBS	1486	broad.mit.edu	37	1	85040025	85040033	+	In_Frame_Del	DEL	AGCAGCGCT	-	-	rs150466708	by1000genomes	TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr1:85040025_85040033delAGCAGCGCT	uc001dka.2	-	1	131_139	c.66_74delAGCGCTGCT	c.(64-75)CTAGCGCTGCTG>CTG	p.22_25LALL>L	CTBS_uc001dkc.2_5'UTR|CTBS_uc001dkd.2_5'UTR|CTBS_uc001dkb.2_5'UTR	NM_004388	NP_004379	Q01459	DIAC_HUMAN	chitobiase, di-N-acetyl- precursor	22_25						lysosome	cation binding				0				all cancers(265;0.00727)|Epithelial(280;0.0192)|OV - Ovarian serous cystadenocarcinoma(397;0.166)		cagcagcgccagcagcgcTAGACCCGGGA	0.589													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	10	42385707	42385722	+	IGR	DEL	AATGGAATCATCATTA	-	-	rs33914712		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr10:42385707_42385722delAATGGAATCATCATTA								None (None upstream) : LOC441666 (441593 downstream)																							aatggaatcgaatggaatcatcattaaatggaatca	0.042													18	105	---	---	---	---					
Unknown	0	broad.mit.edu	37	10	79713755	79713755	+	IGR	DEL	T	-	-	rs80158467		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr10:79713755delT								LOC100128292 (24173 upstream) : POLR3A (22151 downstream)																							tttttctttctttttttttta	0.179													3	3	---	---	---	---					
Unknown	0	broad.mit.edu	37	14	35390295	35390296	+	IGR	INS	-	T	T	rs113610910		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr14:35390295_35390296insT								BAZ1A (45442 upstream) : C14orf19 (18832 downstream)																							CACATATTGCAttttttttttt	0.188													3	3	---	---	---	---					
FNTB	2342	broad.mit.edu	37	14	65453792	65453793	+	Frame_Shift_Ins	INS	-	A	A			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr14:65453792_65453793insA	uc001xia.2	+	1	286_287	c.121_122insA	c.(121-123)GAAfs	p.E41fs	FNTB_uc010tsl.1_Intron|FNTB_uc010tsm.1_Intron|uc001xib.2_5'Flank	NM_002028	NP_002019	P49356	FNTB_HUMAN	farnesyltransferase, CAAX box, beta	41					protein farnesylation	microtubule associated complex	protein binding|protein farnesyltransferase activity			ovary(1)	1				all cancers(60;0.00115)|OV - Ovarian serous cystadenocarcinoma(108;0.00412)|BRCA - Breast invasive adenocarcinoma(234;0.011)		CGACTCGGTGGAAACAGTCACG	0.653													17	32	---	---	---	---					
Unknown	0	broad.mit.edu	37	19	27731986	27731989	+	IGR	DEL	TGTT	-	-			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr19:27731986_27731989delTGTT								None (None upstream) : LOC148189 (549413 downstream)																							ggaaacactctgtttgtaaagtct	0.000													7	414	---	---	---	---					
Unknown	0	broad.mit.edu	37	19	27732215	27732216	+	IGR	INS	-	C	C	rs74197760		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr19:27732215_27732216insC								None (None upstream) : LOC148189 (549186 downstream)																							agaaaaggaaatatcttcgtat	0.000													9	901	---	---	---	---					
Unknown	0	broad.mit.edu	37	2	105387604	105387605	+	IGR	INS	-	A	A			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr2:105387604_105387605insA								LOC150568 (258390 upstream) : POU3F3 (84364 downstream)																							tcaacaacaacaaaaaaaaaaa	0.188													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	2	130676240	130676241	+	IGR	INS	-	AGGA	AGGA			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr2:130676240_130676241insAGGA								None (None upstream) : LOC389033 (4194 downstream)																							ggagggaggggaggaaggaagg	0.000													5	6	---	---	---	---					
Unknown	0	broad.mit.edu	37	22	16915279	16915280	+	IGR	INS	-	TT	TT	rs5746975		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr22:16915279_16915280insTT								OR11H1 (465475 upstream) : CCT8L2 (156368 downstream)																							TCTCCCTCACCAtttttttttt	0.129													3	3	---	---	---	---					
Unknown	0	broad.mit.edu	37	5	41967259	41967260	+	IGR	DEL	GC	-	-			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr5:41967259_41967260delGC								FBXO4 (25596 upstream) : GHR (456766 downstream)																							GCTACTCCAAGCTCTTTAGACT	0.411													2	4	---	---	---	---					
Unknown	0	broad.mit.edu	37	5	90475785	90475786	+	IGR	INS	-	A	A	rs140241795	by1000genomes	TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr5:90475785_90475786insA								GPR98 (15753 upstream) : ARRDC3 (188755 downstream)																							aggaaggaaggaggaaggaagg	0.030													4	2	---	---	---	---					
DSP	1832	broad.mit.edu	37	6	7542148	7542149	+	Translation_Start_Site	INS	-	A	A	rs151331814	by1000genomes	TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr6:7542148_7542149insA	uc003mxp.1	+	1					DSP_uc003mxq.1_Translation_Start_Site	NM_004415	NP_004406	P15924	DESP_HUMAN	desmoplakin isoform I						cellular component disassembly involved in apoptosis|keratinocyte differentiation|peptide cross-linking	cornified envelope|cytoplasm|desmosome	protein binding, bridging|structural constituent of cytoskeleton			central_nervous_system(6)|ovary(2)|skin(1)	9	Ovarian(93;0.0584)	all_hematologic(90;0.236)		OV - Ovarian serous cystadenocarcinoma(45;0.000508)		TGCCCGCCGACATGAGCTGCAA	0.718													3	6	---	---	---	---					
LRP11	84918	broad.mit.edu	37	6	150174150	150174150	+	Frame_Shift_Del	DEL	C	-	-			TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr6:150174150delC	uc003qng.2	-	2	1084	c.760delG	c.(760-762)GTGfs	p.V254fs	LRP11_uc003qnh.1_Frame_Shift_Del_p.V254fs	NM_032832	NP_116221	Q86VZ4	LRP11_HUMAN	low density lipoprotein receptor-related protein	254	PKD.|Extracellular (Potential).					integral to membrane	receptor activity				0		Ovarian(120;0.0907)	BRCA - Breast invasive adenocarcinoma(37;0.193)	OV - Ovarian serous cystadenocarcinoma(155;4.56e-12)|GBM - Glioblastoma multiforme(68;0.225)		TTCATGTCCACTGACGGGTCC	0.532													19	58	---	---	---	---					
Unknown	0	broad.mit.edu	37	7	61968949	61968949	+	IGR	DEL	A	-	-	rs2123586		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr7:61968949delA								None (None upstream) : LOC643955 (782723 downstream)																							ctctgtttgtaaagtctgcaa	0.000													7	807	---	---	---	---					
Unknown	0	broad.mit.edu	37	7	61969534	61969534	+	IGR	DEL	A	-	-	rs56839084		TCGA-EM-A1CW-01A-21D-A13W-08	TCGA-EM-A1CW-10A-01D-A13W-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cfbe393-c8cd-4ab6-8d11-929c1f865e61	7bfe5181-9f97-4320-8ea1-b9cc00aff036	g.chr7:61969534delA								None (None upstream) : LOC643955 (782138 downstream)																							taataaccagacagaatcatt	0.000													7	853	---	---	---	---					
