Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PEX14	5195	broad.mit.edu	37	1	10678475	10678475	+	Splice_Site	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr1:10678475G>A	uc001arn.2	+	5	405	c.384_splice	c.e5+1	p.K128_splice	PEX14_uc009vmu.1_Splice_Site_p.K85_splice|PEX14_uc009vmv.2_Splice_Site_p.K64_splice|PEX14_uc010oam.1_Splice_Site_p.K64_splice|PEX14_uc010oan.1_Splice_Site_p.K85_splice|PEX14_uc009vmw.2_Splice_Site_p.K64_splice	NM_004565	NP_004556	O75381	PEX14_HUMAN	peroxisomal biogenesis factor 14						negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription, DNA-dependent|protein homooligomerization|protein import into peroxisome matrix|transmembrane transport	integral to membrane|nucleus|peroxisomal membrane|protein complex	protein N-terminus binding|transcription corepressor activity			breast(1)	1	Ovarian(185;0.203)	all_lung(284;6.02e-06)|Lung NSC(185;9.62e-06)|Renal(390;0.000147)|Breast(348;0.000932)|Colorectal(325;0.00215)|Hepatocellular(190;0.00913)|Ovarian(437;0.023)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0292)|Colorectal(212;9.13e-08)|COAD - Colon adenocarcinoma(227;2.07e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000482)|Kidney(185;0.00174)|KIRC - Kidney renal clear cell carcinoma(229;0.00457)|STAD - Stomach adenocarcinoma(132;0.0249)|READ - Rectum adenocarcinoma(331;0.0419)		GCTCTACAAGGTGAGTCACCC	0.627000													13	19					0	0	0.105934	0	0
CROCCL1	84809	broad.mit.edu	37	1	16945460	16945460	+	RNA	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr1:16945460C>T	uc010ocf.1	-	4		c.697G>A			CROCCL1_uc009vov.1_RNA|CROCCL1_uc001aze.2_RNA|CROCCL1_uc001azf.2_RNA					Homo sapiens mRNA for FLJ00313 protein.												0						GACGGCAGGCCTACCCGGTCC	0.642000													10	155					0	0	0.069234	0	0
ZMYND12	84217	broad.mit.edu	37	1	42921731	42921731	+	Translation_Start_Site	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr1:42921731G>A	uc001chj.2	-	1	208	c.-62C>T	c.(-64--60)GACGC>GATGC		ZMYND12_uc010ojt.1_Translation_Start_Site|PPCS_uc001chk.2_5'Flank|PPCS_uc001chl.2_5'Flank	NM_032257	NP_115633	Q9H0C1	ZMY12_HUMAN	zinc finger, MYND-type containing 12 isoform 1							intracellular	zinc ion binding			ovary(1)	1	Ovarian(52;0.00744)|all_hematologic(146;0.0977)|Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0505)				GAACCCCGGCGTCACGTGACG	0.597000													3	5					0	0	0.004672	0	0
ZCCHC11	23318	broad.mit.edu	37	1	52961169	52961169	+	Missense_Mutation	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr1:52961169T>C	uc001ctx.2	-	6	1430	c.1196A>G	c.(1195-1197)TAT>TGT	p.Y399C	ZCCHC11_uc001cty.2_Missense_Mutation_p.Y399C|ZCCHC11_uc001ctz.2_Missense_Mutation_p.Y399C|ZCCHC11_uc009vze.1_Missense_Mutation_p.Y399C|ZCCHC11_uc009vzf.1_Missense_Mutation_p.Y158C|ZCCHC11_uc001cub.2_Missense_Mutation_p.Y399C|ZCCHC11_uc001cuc.2_RNA	NM_015269	NP_056084	Q5TAX3	TUT4_HUMAN	zinc finger, CCHC domain containing 11 isoform	399					miRNA catabolic process|pre-miRNA processing|RNA 3'-end processing|stem cell maintenance	cytoplasm|nucleolus	nucleic acid binding|protein binding|protein binding|RNA uridylyltransferase activity|zinc ion binding			ovary(2)|skin(1)	3						AGATGAGCCATACAACCTAAG	0.338000													25	30					0	0	0.091800	0	0
GALNT2	2590	broad.mit.edu	37	1	230372159	230372159	+	Silent	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr1:230372159C>T	uc010pwa.1	+	5	606	c.534C>T	c.(532-534)AGC>AGT	p.S178S	GALNT2_uc010pvy.1_Silent_p.S140S|GALNT2_uc010pvz.1_RNA	NM_004481	NP_004472	Q10471	GALT2_HUMAN	polypeptide N-acetylgalactosaminyltransferase 2	178	Lumenal (Potential).|Catalytic subdomain A.				immunoglobulin biosynthetic process|protein O-linked glycosylation via serine|protein O-linked glycosylation via threonine	extracellular region|Golgi cisterna membrane|integral to Golgi membrane|perinuclear region of cytoplasm	manganese ion binding|polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			ovary(2)	2	Breast(184;0.193)|Ovarian(103;0.249)	all_cancers(173;0.156)|Prostate(94;0.179)				ATGACTACAGCAATGATCGTG	0.448000													17	39					0	0	0.049695	0	0
TMEM72	643236	broad.mit.edu	37	10	45429133	45429133	+	Missense_Mutation	SNP	G	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr10:45429133G>C	uc001jbn.2	+	4	455	c.258G>C	c.(256-258)TGG>TGC	p.W86C	uc001jbk.1_Intron|uc001jbl.2_Intron|TMEM72_uc009xmm.1_5'UTR	NM_001123376	NP_001116848	A0PK05	TMM72_HUMAN	transmembrane protein 72	86	Helical; (Potential).					integral to membrane					0						AAGCCCACTGGCTGGGCTGCT	0.602000													24	21					0	0	0.076483	0	0
Unknown	0	broad.mit.edu	37	10	48968566	48968566	+	RNA	SNP	A	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr10:48968566A>G	uc001jgc.1	+	3		c.1234A>G								full-length cDNA clone CS0DI009YC01 of Placenta Cot 25-normalized of Homo sapiens (human).																		ACAGGATAACAAACTGGAAAA	0.284000													3	39					0	0	0.004672	0	0
MUC5B	727897	broad.mit.edu	37	11	1275533	1275533	+	Missense_Mutation	SNP	G	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr11:1275533G>C	uc009ycr.1	+	56	16566	c.16440G>C	c.(16438-16440)ATG>ATC	p.M5480I	MUC5B_uc001ltb.2_Missense_Mutation_p.M5146I	NM_017511	NP_059981	Q9HC84	MUC5B_HUMAN	SubName: Full=Mucin 5AC, oligomeric mucus/gel-forming;	5143	VWFD 4.				cell adhesion	extracellular region	extracellular matrix structural constituent|protein binding				0		all_cancers(49;6.97e-08)|all_epithelial(84;3.45e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.229)		BRCA - Breast invasive adenocarcinoma(625;0.00141)|Lung(200;0.0853)|LUSC - Lung squamous cell carcinoma(625;0.1)		ACAAGTCCATGGATATCGTCC	0.642000													20	29					0	0	0.043863	0	0
LOC650368	650368	broad.mit.edu	37	11	3427845	3427845	+	RNA	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr11:3427845C>T	uc010qxs.1	+	9		c.838C>T			LOC650368_uc001lxx.2_RNA|LOC650368_uc001lxy.2_RNA	NR_024248				Homo sapiens cDNA FLJ41654 fis, clone FEBRA2025463, weakly  similar to Homo sapiens HMT-1 mRNA for beta-1,4 mannosyltransferase.												0						CTTCAAGTGGCAGGAGCAGAA	0.587000													7	44					0	0	0.029380	0	0
LGALS12	85329	broad.mit.edu	37	11	63273900	63273900	+	Silent	SNP	G	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr11:63273900G>C	uc001nxa.2	+	1	377	c.36G>C	c.(34-36)ACG>ACC	p.T12T	LGALS12_uc001nxb.2_Silent_p.T12T|LGALS12_uc001nxc.2_Silent_p.T12T|LGALS12_uc001nxd.2_5'Flank|LGALS12_uc001nxe.2_5'Flank|LGALS12_uc009yot.2_5'Flank	NM_033101	NP_149092	Q96DT0	LEG12_HUMAN	lectin, galactoside-binding, soluble, 12 isoform	12					apoptosis|induction of apoptosis by intracellular signals	nucleus	lactose binding			ovary(2)	2						CTCCTGGAACGAGGATCTACA	0.572000													4	71					0	0	0.014758	0	0
CATSPER1	117144	broad.mit.edu	37	11	65788966	65788966	+	Splice_Site	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr11:65788966C>T	uc001ogt.2	-	4	1829	c.1691_splice	c.e4+1	p.S564_splice		NM_053054	NP_444282	Q8NEC5	CTSR1_HUMAN	sperm-associated cation channel 1						cell differentiation|multicellular organismal development|spermatogenesis	cilium|flagellar membrane|integral to membrane	protein binding			ovary(2)	2						TGGCCACTGACCTGAGCCTCC	0.627000													9	12					0	0	0.080935	0	0
BCL9L	283149	broad.mit.edu	37	11	118771983	118771983	+	Silent	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr11:118771983C>T	uc001pug.2	-	6	3434	c.2469G>A	c.(2467-2469)CAG>CAA	p.Q823Q	BCL9L_uc009zal.2_Silent_p.Q818Q	NM_182557	NP_872363	Q86UU0	BCL9L_HUMAN	B-cell CLL/lymphoma 9-like	823	Met-rich.				negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of epithelial to mesenchymal transition|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent		transcription coactivator activity			ovary(1)|pancreas(1)	2	all_hematologic(175;0.0839)	Medulloblastoma(222;0.0425)|all_hematologic(192;0.103)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;7.66e-05)		CACTGCTGTTCTGGGCCCGAA	0.652000													33	47					0	0	0.054565	0	0
ARHGEF12	23365	broad.mit.edu	37	11	120352127	120352127	+	Missense_Mutation	SNP	G	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr11:120352127G>T	uc001pxl.1	+	39	4403	c.4396G>T	c.(4396-4398)GCA>TCA	p.A1466S	ARHGEF12_uc009zau.1_Missense_Mutation_p.A1363S	NM_015313	NP_056128	Q9NZN5	ARHGC_HUMAN	Rho guanine nucleotide exchange factor (GEF) 12	1466					apoptosis|axon guidance|G-protein coupled receptor protein signaling pathway|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|membrane	G-protein-coupled receptor binding|GTPase activator activity|Rho guanyl-nucleotide exchange factor activity			lung(2)|breast(2)|skin(2)|ovary(1)	7		Breast(109;0.000813)|Medulloblastoma(222;0.0425)|Hepatocellular(160;0.0831)|all_hematologic(192;0.107)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;4.88e-06)|OV - Ovarian serous cystadenocarcinoma(223;0.231)		CTCCGATGGGGCAATTTCACC	0.537000			T	MLL	AML								25	49					3.6726e-16	3.98999e-16	0.091800	1	0
LARP4	113251	broad.mit.edu	37	12	50847454	50847454	+	Missense_Mutation	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr12:50847454T>C	uc001rwp.1	+	9	1160	c.1016T>C	c.(1015-1017)CTG>CCG	p.L339P	LARP4_uc001rwo.1_Missense_Mutation_p.L345P|LARP4_uc001rwq.1_Intron|LARP4_uc001rwr.1_Missense_Mutation_p.L339P|LARP4_uc001rws.1_Missense_Mutation_p.L338P|LARP4_uc009zlr.1_Missense_Mutation_p.L158P|LARP4_uc001rwt.1_Intron|LARP4_uc001rwm.2_Missense_Mutation_p.L339P|LARP4_uc001rwn.2_Missense_Mutation_p.L269P	NM_052879	NP_443111	Q71RC2	LARP4_HUMAN	c-Mpl binding protein isoform a	339							nucleotide binding|RNA binding			ovary(1)	1						GAAACACCACTGGTAAGTGAG	0.353000													54	56					0	0	0.048971	0	0
GRASP	160622	broad.mit.edu	37	12	52401016	52401016	+	Silent	SNP	C	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr12:52401016C>A	uc001rzo.1	+	1	269	c.213C>A	c.(211-213)CTC>CTA	p.L71L		NM_181711	NP_859062	Q7Z6J2	GRASP_HUMAN	GRP1 (general receptor for phosphoinositides	71						cell junction|perinuclear region of cytoplasm|postsynaptic membrane				central_nervous_system(1)|skin(1)	2				BRCA - Breast invasive adenocarcinoma(357;0.0967)		ACCGCGCGCTCGCCGTGTCCG	0.741000													12	8					0.00136819	0.00140001	0.093190	1	0
DTX1	1840	broad.mit.edu	37	12	113534672	113534672	+	Silent	SNP	C	T	T	rs142267522	byFrequency	TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr12:113534672C>T	uc001tuk.1	+	9	2127	c.1791C>T	c.(1789-1791)GAC>GAT	p.D597D		NM_004416	NP_004407	Q86Y01	DTX1_HUMAN	deltex homolog 1	597					negative regulation of neuron differentiation|Notch signaling pathway|regulation of Notch signaling pathway|transcription from RNA polymerase II promoter	cytoplasm|nucleus	Notch binding|SH3 domain binding|transcription coactivator activity|ubiquitin protein ligase binding|zinc ion binding			lung(2)|ovary(1)|central_nervous_system(1)	4						GCTACCCGGACGCTAGCTACC	0.637000													3	42					0	0	0.009096	0	0
LOC284232	284232	broad.mit.edu	37	13	19414102	19414102	+	RNA	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr13:19414102C>T	uc010tcj.1	-	1		c.32008G>A				NR_027995				Homo sapiens ankyrin repeat domain 20 family, member A2 pseudogene (LOC284232), non-coding RNA.												0						GAATTTTTACCAAAGATTGAT	0.274000													4	26					0	0	0.009096	0	0
MAPK6	5597	broad.mit.edu	37	15	52338881	52338881	+	Missense_Mutation	SNP	A	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr15:52338881A>G	uc002abp.2	+	2	1018	c.224A>G	c.(223-225)GAT>GGT	p.D75G		NM_002748	NP_002739	Q16659	MK06_HUMAN	mitogen-activated protein kinase 6	75	Protein kinase.				cell cycle		ATP binding|MAP kinase activity			lung(3)|ovary(1)	4				all cancers(107;0.0028)		CTTGACCATGATAACATTGTG	0.398000													42	66					0	0	0.092188	0	0
RAB11FIP3	9727	broad.mit.edu	37	16	568988	568988	+	Silent	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr16:568988G>A	uc002chf.2	+	10	2025	c.1686G>A	c.(1684-1686)ACG>ACA	p.T562T	RAB11FIP3_uc010uuf.1_Silent_p.T266T|RAB11FIP3_uc010uug.1_Silent_p.T297T	NM_014700	NP_055515	O75154	RFIP3_HUMAN	rab11-family interacting protein 3 isoform 1	562	Potential.|ARF-binding domain (ABD).				cell cycle|cytokinesis|endocytic recycling|protein transport	centrosome|cleavage furrow|midbody|recycling endosome membrane	ADP-ribosylation factor binding|calcium ion binding|protein homodimerization activity|Rab GTPase binding				0		Hepatocellular(16;0.0218)				GGTCCTGCACGCCCTGTCTGA	0.612000													30	81					0	0	0.045705	0	0
ULK2	9706	broad.mit.edu	37	17	19770705	19770705	+	Missense_Mutation	SNP	T	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr17:19770705T>A	uc002gwm.3	-	1	535	c.26A>T	c.(25-27)TAC>TTC	p.Y9F	ULK2_uc002gwn.2_Missense_Mutation_p.Y9F	NM_001142610	NP_001136082	Q8IYT8	ULK2_HUMAN	unc-51-like kinase 2	9	Protein kinase.				signal transduction		ATP binding|protein binding|protein serine/threonine kinase activity			skin(2)|large_intestine(1)|stomach(1)	4	all_cancers(12;4.97e-05)|all_epithelial(12;0.00362)|Breast(13;0.186)					CCTCTTGCTGTACTCGAAGTC	0.617000													23	18					0	0	0.099896	0	0
Unknown	0	broad.mit.edu	37	17	25746859	25746859	+	RNA	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr17:25746859T>C	uc002gzg.2	+	4		c.383T>C								Homo sapiens similar to ubiquitin specific protease 6, mRNA (cDNA clone IMAGE:5168266), with apparent retained intron.																		ACAGCAGCACTGATCGCTTTG	0.537000													6	21					0	0	0.029380	0	0
EVI2A	2123	broad.mit.edu	37	17	29645740	29645740	+	Missense_Mutation	SNP	A	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr17:29645740A>T	uc002hgm.2	-	2	507	c.292T>A	c.(292-294)TCT>ACT	p.S98T	NF1_uc002hgg.2_Intron|NF1_uc002hgh.2_Intron|NF1_uc002hgi.1_Intron|NF1_uc010cso.2_Intron|EVI2A_uc002hgl.2_Missense_Mutation_p.S121T	NM_014210	NP_055025	P22794	EVI2A_HUMAN	ecotropic viral integration site 2A isoform 2	98	Extracellular (Potential).					integral to membrane	transmembrane receptor activity			ovary(1)|breast(1)	2		all_cancers(10;6.97e-11)|all_epithelial(10;0.0051)|all_hematologic(16;0.0149)|Breast(31;0.0155)|Myeloproliferative disorder(56;0.0255)|Acute lymphoblastic leukemia(14;0.0257)|all_lung(9;0.0468)|Lung NSC(157;0.094)		UCEC - Uterine corpus endometrioid carcinoma (4;6.64e-05)|all cancers(4;5.94e-13)|Epithelial(4;7.98e-12)|OV - Ovarian serous cystadenocarcinoma(4;9.4e-12)|GBM - Glioblastoma multiforme(4;0.18)		CTGACGACAGAAGGTATATAA	0.368000													104	72					0	0	0.048971	0	0
HNF1B	6928	broad.mit.edu	37	17	36099582	36099582	+	Silent	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr17:36099582T>C	uc002hok.3	-	2	614	c.393A>G	c.(391-393)CAA>CAG	p.Q131Q	HNF1B_uc010wdi.1_Silent_p.Q131Q	NM_000458	NP_000449	P35680	HNF1B_HUMAN	hepatocyte nuclear factor 1-beta isoform 1	131					endocrine pancreas development|genitalia development|kidney development|positive regulation of transcription initiation from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|pronephric nephron tubule development|regulation of pronephros size	nucleus	DNA binding|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			ovary(3)	3		Breast(25;0.00765)|Ovarian(249;0.15)	STAD - Stomach adenocarcinoma(1;0.0142)			GGATGTTGTGTTGCTGCATGT	0.547000									Hereditary_Prostate_Cancer				39	23					0	0	0.086207	0	0
KRT26	353288	broad.mit.edu	37	17	38926071	38926071	+	Nonsense_Mutation	SNP	C	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr17:38926071C>A	uc002hvf.2	-	5	950	c.904G>T	c.(904-906)GAG>TAG	p.E302*		NM_181539	NP_853517	Q7Z3Y9	K1C26_HUMAN	keratin 26	302	Rod.|Coil 2.					intermediate filament	structural molecule activity				0		Breast(137;0.00526)				TCGGTCAGCTCATTTCTGGCT	0.463000													60	132					8.13277e-46	9.17544e-46	0.048971	1	0
LRRC37A4	55073	broad.mit.edu	37	17	43587657	43587657	+	RNA	SNP	C	T	T	rs148404065	by1000genomes	TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr17:43587657C>T	uc002ije.2	-	3		c.1397G>A			uc010wjp.1_RNA					Homo sapiens cDNA FLJ34414 fis, clone HEART2003168, highly similar to Homo sapiens c114 SLIT-like testicular protein (LOC474170), mRNA.												0						GGTGACAACACATCTGTTTTA	0.279000													5	50					0	0	0.014758	0	0
NARF	26502	broad.mit.edu	37	17	80443514	80443514	+	Silent	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr17:80443514C>T	uc002kfg.3	+	10	1253	c.1113C>T	c.(1111-1113)GTC>GTT	p.V371V	NARF_uc002kff.3_Silent_p.V312V|NARF_uc010dit.2_Silent_p.V417V|NARF_uc002kfj.3_Silent_p.V323V|NARF_uc002kfi.3_RNA|NARF_uc002kfh.3_Silent_p.V417V|NARF_uc002kfk.2_Intron	NM_012336	NP_036468	Q9UHQ1	NARF_HUMAN	nuclear prelamin A recognition factor isoform a	371						lamin filament	lamin binding			skin(1)	1	Breast(20;0.00106)|all_neural(118;0.0804)		OV - Ovarian serous cystadenocarcinoma(97;0.0143)|BRCA - Breast invasive adenocarcinoma(99;0.0369)			TTGTGGAGGTCCTCGCCTGTG	0.572000													77	27					0	0	0.048971	0	0
PQLC1	80148	broad.mit.edu	37	18	77679262	77679262	+	Missense_Mutation	SNP	A	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr18:77679262A>T	uc002lnl.2	-	5	702	c.530T>A	c.(529-531)CTG>CAG	p.L177Q	PQLC1_uc010dre.2_Missense_Mutation_p.L94Q|PQLC1_uc002lnk.2_Missense_Mutation_p.L159Q|PQLC1_uc010xfm.1_Intron	NM_025078	NP_079354	Q8N2U9	PQLC1_HUMAN	PQ loop repeat containing 1 isoform 1	177	Helical; (Potential).					integral to membrane				large_intestine(1)|ovary(1)	2		Esophageal squamous(42;0.0212)|Melanoma(33;0.2)		OV - Ovarian serous cystadenocarcinoma(15;8.2e-07)|BRCA - Breast invasive adenocarcinoma(31;0.0258)		CAGCACAGCCAGGAAGCCCAG	0.652000													18	29					0	0	0.033300	0	0
MUC16	94025	broad.mit.edu	37	19	9077786	9077786	+	Silent	SNP	G	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr19:9077786G>T	uc002mkp.2	-	3	9864	c.9660C>A	c.(9658-9660)ATC>ATA	p.I3220I		NM_024690	NP_078966	Q8WXI7	MUC16_HUMAN	mucin 16	3221	Thr-rich.|Extracellular (Potential).				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			lung(30)|ovary(15)|breast(8)|large_intestine(1)|skin(1)|prostate(1)|pancreas(1)	57						CAGTGGACCTGATCTCTGGGC	0.498000													61	74					1.53716e-24	1.69087e-24	0.048971	1	0
ANGPTL6	83854	broad.mit.edu	37	19	10206815	10206815	+	Missense_Mutation	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr19:10206815C>T	uc002mmx.1	-	2	543	c.425G>A	c.(424-426)CGC>CAC	p.R142H	ANGPTL6_uc002mmy.1_Missense_Mutation_p.R142H	NM_031917	NP_114123	Q8NI99	ANGL6_HUMAN	angiopoietin-like 6 precursor	142					angiogenesis|cell differentiation|signal transduction	extracellular space	receptor binding				0			OV - Ovarian serous cystadenocarcinoma(20;3.58e-08)|Epithelial(33;2.5e-05)|all cancers(31;5.96e-05)			GTTGAGCACGCGCTCCCCGAG	0.627000													3	5					0	0	0.004672	0	0
LMTK3	114783	broad.mit.edu	37	19	49000760	49000760	+	Missense_Mutation	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr19:49000760G>A	uc002pjk.2	-	12	3653	c.3653C>T	c.(3652-3654)ACG>ATG	p.T1218M		NM_001080434	NP_001073903			lemur tyrosine kinase 3											lung(5)|central_nervous_system(1)	6		all_lung(116;0.000147)|Lung NSC(112;0.000251)|all_epithelial(76;0.000326)|all_neural(266;0.0506)|Ovarian(192;0.113)		OV - Ovarian serous cystadenocarcinoma(262;0.000114)|all cancers(93;0.000141)|Epithelial(262;0.00854)|GBM - Glioblastoma multiforme(486;0.0231)		GCTGAGTGCCGTGTCTCCGCC	0.726000													3	32					0	0	0.004672	0	0
SRBD1	55133	broad.mit.edu	37	2	45616665	45616665	+	Silent	SNP	G	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr2:45616665G>C	uc002rus.2	-	21	2848	c.2772C>G	c.(2770-2772)GGC>GGG	p.G924G	SRBD1_uc010yoc.1_Silent_p.G443G	NM_018079	NP_060549	Q8N5C6	SRBD1_HUMAN	S1 RNA binding domain 1	924	S1 motif.				nucleobase, nucleoside, nucleotide and nucleic acid metabolic process		hydrolase activity, acting on ester bonds|RNA binding			central_nervous_system(1)	1		all_hematologic(82;0.166)|Acute lymphoblastic leukemia(82;0.17)	LUSC - Lung squamous cell carcinoma(58;0.0917)|Lung(47;0.154)			TCTCAACTTTGCCTGTAAGAA	0.378000													17	42					0	0	0.028581	0	0
ZNF514	84874	broad.mit.edu	37	2	95815137	95815137	+	Missense_Mutation	SNP	A	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr2:95815137A>C	uc002sue.1	-	5	1467	c.1093T>G	c.(1093-1095)TTT>GTT	p.F365V	ZNF514_uc002sud.1_Missense_Mutation_p.F438V	NM_032788	NP_116177	Q96K75	ZN514_HUMAN	zinc finger protein 514	365	C2H2-type 6.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0						CCAGTGTGAAATCTGTAATGT	0.398000													30	39					0	0	0.041601	0	0
UGT1A3	54659	broad.mit.edu	37	2	234638329	234638329	+	Missense_Mutation	SNP	A	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr2:234638329A>G	uc002vuy.2	+	1	557	c.557A>G	c.(556-558)CAG>CGG	p.Q186R	UGT1A8_uc010zmv.1_Intron|UGT1A8_uc002vup.2_Intron|UGT1A10_uc002vuq.3_Intron|UGT1A10_uc002vur.2_Intron|UGT1A9_uc010zmw.1_Intron|UGT1A9_uc002vus.2_Intron|UGT1A7_uc010zmx.1_Intron|UGT1A7_uc002vut.2_Intron|UGT1A6_uc002vuu.2_Intron|UGT1A6_uc010zmy.1_Intron|UGT1A6_uc002vuv.3_Intron|UGT1A5_uc010zmz.1_Intron|UGT1A5_uc002vuw.2_Intron|UGT1A4_uc010zna.1_Intron|UGT1A4_uc002vux.2_Intron|UGT1A3_uc010znb.1_Missense_Mutation_p.Q186R	NM_019093	NP_061966	P35503	UD13_HUMAN	UDP glycosyltransferase 1 family, polypeptide A3	186					flavonoid metabolic process|xenobiotic metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	enzyme binding|glucuronosyltransferase activity|protein heterodimerization activity|protein homodimerization activity|retinoic acid binding			ovary(1)	1		Breast(86;0.000765)|all_lung(227;0.00266)|Renal(207;0.00339)|all_hematologic(139;0.0116)|Acute lymphoblastic leukemia(138;0.0327)|Lung NSC(271;0.0456)|Lung SC(224;0.128)		Epithelial(121;2.4e-18)|BRCA - Breast invasive adenocarcinoma(100;0.000476)|Lung(119;0.00243)|LUSC - Lung squamous cell carcinoma(224;0.00599)		AAGGGCACACAGTGTCCAAAC	0.458000													106	116					0	0	0.048971	0	0
SCLY	51540	broad.mit.edu	37	2	238990470	238990470	+	Missense_Mutation	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr2:238990470T>C	uc010fyv.2	+	5	669	c.605T>C	c.(604-606)ATT>ACT	p.I202T	SCLY_uc002vxm.3_Missense_Mutation_p.I169T|SCLY_uc002vxn.2_Missense_Mutation_p.I202T|SCLY_uc010znq.1_Intron|SCLY_uc010znr.1_Missense_Mutation_p.I108T	NM_016510	NP_057594	Q96I15	SCLY_HUMAN	selenocysteine lyase	202					cellular amino acid metabolic process	cytosol	pyridoxal phosphate binding|selenocysteine lyase activity|transferase activity			ovary(2)	2		Breast(86;7.61e-05)|Renal(207;0.00183)|Ovarian(221;0.0481)|all_hematologic(139;0.158)|all_lung(227;0.198)|Melanoma(123;0.203)|Hepatocellular(293;0.244)		Epithelial(121;1.37e-23)|OV - Ovarian serous cystadenocarcinoma(60;4.6e-12)|Kidney(56;3.21e-09)|KIRC - Kidney renal clear cell carcinoma(57;8.25e-08)|BRCA - Breast invasive adenocarcinoma(100;0.000128)|Lung(119;0.0118)|LUSC - Lung squamous cell carcinoma(224;0.0285)		GAGACTGGCATTGTCATGGTG	0.572000													19	27					0	0	0.038395	0	0
SNTA1	6640	broad.mit.edu	37	20	32026771	32026771	+	Silent	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr20:32026771G>A	uc002wzd.1	-	2	644	c.372C>T	c.(370-372)GAC>GAT	p.D124D	SNTA1_uc010zuf.1_Silent_p.D124D	NM_003098	NP_003089	Q13424	SNTA1_HUMAN	acidic alpha 1 syntrophin	124	PH 1.|PDZ.				muscle contraction	cell junction|cytoplasm|cytoskeleton|sarcolemma	actin binding|calmodulin binding			skin(1)	1						CCTCTGTCTGGTCAGCTGCCA	0.527000													70	141					0	0	0.048971	0	0
RALGAPB	57148	broad.mit.edu	37	20	37153507	37153507	+	Missense_Mutation	SNP	C	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr20:37153507C>A	uc002xiw.2	+	11	1963	c.1706C>A	c.(1705-1707)CCT>CAT	p.P569H	RALGAPB_uc010zvz.1_3'UTR|RALGAPB_uc002xix.2_Missense_Mutation_p.P569H|RALGAPB_uc002xiy.1_Missense_Mutation_p.P569H|RALGAPB_uc002xiz.2_Missense_Mutation_p.P347H|RALGAPB_uc002xja.1_Missense_Mutation_p.P296H	NM_020336	NP_065069	Q86X10	RLGPB_HUMAN	Ral GTPase activating protein, beta subunit	569					activation of Ral GTPase activity	intracellular	protein heterodimerization activity|Ral GTPase activator activity			pancreas(1)|skin(1)	2						AACTCTCCTCCTTTGTTCTGC	0.393000													137	84					2.0029e-70	2.28903e-70	0.048971	1	0
SULF2	55959	broad.mit.edu	37	20	46291842	46291842	+	Missense_Mutation	SNP	T	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr20:46291842T>A	uc002xto.2	-	17	2672	c.2342A>T	c.(2341-2343)TAC>TTC	p.Y781F	SULF2_uc002xtr.2_Missense_Mutation_p.Y781F|SULF2_uc002xtq.2_Missense_Mutation_p.Y781F|SULF2_uc010zyd.1_Missense_Mutation_p.Y60F	NM_018837	NP_061325	Q8IWU5	SULF2_HUMAN	sulfatase 2 isoform a precursor	781					bone development|heparan sulfate proteoglycan metabolic process|kidney development|negative regulation of fibroblast growth factor receptor signaling pathway	cell surface|endoplasmic reticulum|extracellular space|Golgi stack	arylsulfatase activity|calcium ion binding			ovary(2)|breast(2)|pancreas(1)|skin(1)	6						GAGATCAAAGTACTCTAGGAA	0.547000											OREG0026005	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	45	42					0	0	0.045515	0	0
DDX27	55661	broad.mit.edu	37	20	47835928	47835928	+	Missense_Mutation	SNP	A	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr20:47835928A>C	uc002xuh.2	+	1	97	c.36A>C	c.(34-36)GAA>GAC	p.E12D		NM_017895	NP_060365	Q96GQ7	DDX27_HUMAN	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	12						nucleus	ATP binding|ATP-dependent helicase activity|nucleic acid binding|protein binding			kidney(2)	2			BRCA - Breast invasive adenocarcinoma(12;0.000899)|COAD - Colon adenocarcinoma(4;0.14)|Colorectal(8;0.166)			GAGGCTGCGAAAAGTTAAGGG	0.607000													12	29					0	0	0.093190	0	0
CRYAA	1409	broad.mit.edu	37	21	44589374	44589374	+	Silent	SNP	C	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr21:44589374C>G	uc002zdd.1	+	1	234	c.165C>G	c.(163-165)ACC>ACG	p.T55T		NM_000394	NP_000385	P02489	CRYAA_HUMAN	crystallin, alpha A	55					anti-apoptosis|negative regulation of intracellular transport|protein homooligomerization|response to heat|visual perception	cytoplasm|nucleus	structural constituent of eye lens|unfolded protein binding			breast(1)|central_nervous_system(1)	2						TCTTCCGCACCGTGCTGGACT	0.622000													74	69					0	0	0.048971	0	0
UQCR10	29796	broad.mit.edu	37	22	30163434	30163434	+	Missense_Mutation	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr22:30163434G>A	uc003agq.1	+	1	77	c.47G>A	c.(46-48)CGC>CAC	p.R16H	ZMAT5_uc003agm.2_5'Flank|ZMAT5_uc003agn.2_5'Flank|ZMAT5_uc003ago.1_5'Flank|UQCR10_uc003agp.1_Missense_Mutation_p.R16H	NM_013387	NP_037519	Q9UDW1	QCR9_HUMAN	ubiquinol-cytochrome c reductase complex 7.2kDa	16					mitochondrial electron transport, ubiquinol to cytochrome c	mitochondrial inner membrane|respiratory chain	ubiquinol-cytochrome-c reductase activity			ovary(1)	1						CTGCTGTTCCGCAGGACCTCC	0.612000													25	28					0	0	0.091800	0	0
SEC14L3	266629	broad.mit.edu	37	22	30866522	30866522	+	Missense_Mutation	SNP	A	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr22:30866522A>T	uc003ahy.2	-	2	191	c.102T>A	c.(100-102)GAT>GAA	p.D34E	SEC14L3_uc003ahz.2_5'UTR|SEC14L3_uc003aia.2_5'UTR|SEC14L3_uc003aib.2_5'UTR	NM_174975	NP_777635	Q9UDX4	S14L3_HUMAN	SEC14-like 3	34						integral to membrane|intracellular	lipid binding|transporter activity			ovary(3)|pancreas(1)|skin(1)	5					Vitamin E(DB00163)	GGAAATAATCATCAGGGTTGG	0.567000													25	27					0	0	0.099896	0	0
SUN2	25777	broad.mit.edu	37	22	39138452	39138452	+	Silent	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr22:39138452G>A	uc003awh.1	-	10	1206	c.922C>T	c.(922-924)CTG>TTG	p.L308L	SUN2_uc011anz.1_Silent_p.L343L|SUN2_uc011aoa.1_Silent_p.L297L|SUN2_uc003awi.1_Silent_p.L308L|SUN2_uc010gxq.1_Silent_p.L329L|SUN2_uc010gxr.1_Silent_p.L308L|SUN2_uc010gxs.1_Silent_p.L308L	NM_015374	NP_056189	Q9UH99	SUN2_HUMAN	unc-84 homolog B	308	Perinuclear space.				centrosome localization|cytoskeletal anchoring at nuclear membrane|mitotic spindle organization|nuclear envelope organization|nuclear matrix anchoring at nuclear membrane|nuclear migration along microfilament|positive regulation of cell migration	endosome membrane|integral to membrane|nuclear inner membrane|SUN-KASH complex	lamin binding|microtubule binding			large_intestine(1)|skin(1)	2						CGCAGCTCCAGACGTTCCAGC	0.647000													17	23					0	0	0.033300	0	0
ANKRD28	23243	broad.mit.edu	37	3	15751227	15751227	+	Missense_Mutation	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr3:15751227T>C	uc003caj.1	-	13	1407	c.1264A>G	c.(1264-1266)AAC>GAC	p.N422D	ANKRD28_uc003cai.1_Missense_Mutation_p.N268D|ANKRD28_uc011avz.1_Missense_Mutation_p.N268D|ANKRD28_uc003cak.1_RNA|ANKRD28_uc011awa.1_RNA|ANKRD28_uc003cal.1_Missense_Mutation_p.N452D|ANKRD28_uc003cam.2_Missense_Mutation_p.N455D	NM_015199	NP_056014	O15084	ANR28_HUMAN	ankyrin repeat domain 28	422	ANK 12.					nucleoplasm	protein binding			breast(1)	1						AGCAGAAGGTTTAGGCACTCC	0.323000													8	6					0	0	0.047766	0	0
SACM1L	22908	broad.mit.edu	37	3	45780273	45780273	+	Missense_Mutation	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr3:45780273G>A	uc003cos.2	+	18	1681	c.1477G>A	c.(1477-1479)GAT>AAT	p.D493N	SACM1L_uc011bag.1_Missense_Mutation_p.D390N|SACM1L_uc011bah.1_Missense_Mutation_p.D427N|SACM1L_uc003cot.2_Missense_Mutation_p.D136N	NM_014016	NP_054735	Q9NTJ5	SAC1_HUMAN	suppressor of actin 1	493						Golgi apparatus				ovary(1)	1				BRCA - Breast invasive adenocarcinoma(193;0.0102)|KIRC - Kidney renal clear cell carcinoma(197;0.0234)|Kidney(197;0.0277)		TCTGTTCTAGGATTCCATAGA	0.363000													29	23					0	0	0.030593	0	0
ACPL2	92370	broad.mit.edu	37	3	140979087	140979087	+	Missense_Mutation	SNP	C	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr3:140979087C>A	uc003etu.2	+	4	369	c.70C>A	c.(70-72)CTG>ATG	p.L24M	ACPL2_uc003etv.2_Missense_Mutation_p.L24M|ACPL2_uc011bna.1_Translation_Start_Site|ACPL2_uc011bnb.1_5'Flank	NM_152282	NP_689495	Q8TE99	ACPL2_HUMAN	acid phosphatase-like 2 precursor	24						extracellular region	acid phosphatase activity			skin(1)	1						GAGCCTCAGCCTGCAGTTCTG	0.517000													21	19					3.51602e-12	3.77329e-12	0.049695	1	0
ZNF721	170960	broad.mit.edu	37	4	437056	437056	+	Silent	SNP	A	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr4:437056A>G	uc003gag.2	-	3	1891	c.1200T>C	c.(1198-1200)AGT>AGC	p.S400S	ABCA11P_uc003gac.2_Intron|ABCA11P_uc003gad.2_Intron|ABCA11P_uc011buv.1_Intron|ABCA11P_uc003gae.2_Intron|ABCA11P_uc010ibd.1_Intron|ZNF721_uc003gaf.3_Silent_p.S432S|ZNF721_uc010ibe.2_Silent_p.S388S	NM_133474	NP_597731	D9N162	D9N162_HUMAN	zinc finger protein 721	400						intracellular	nucleic acid binding|zinc ion binding			ovary(1)	1						GGTTTGTTGAACTATTAAAGG	0.428000													23	28					0	0	0.069288	0	0
SLC26A1	10861	broad.mit.edu	37	4	983983	983983	+	Silent	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr4:983983T>C	uc003gcb.2	-	4	1122	c.744A>G	c.(742-744)ACA>ACG	p.T248T	SLC26A1_uc003gbx.2_Intron|IDUA_uc003gby.2_Intron|IDUA_uc003gbz.2_Intron|IDUA_uc003gca.2_Intron|SLC26A1_uc003gcc.2_Silent_p.T248T	NM_213613	NP_998778	Q9H2B4	S26A1_HUMAN	solute carrier family 26, member 1 isoform a	248						integral to membrane|plasma membrane	secondary active sulfate transmembrane transporter activity			skin(1)	1			OV - Ovarian serous cystadenocarcinoma(23;0.0158)			GGCTCAGCCATGTGAGGACCA	0.697000													5	2					0	0	0.014758	0	0
MFSD10	10227	broad.mit.edu	37	4	2934166	2934166	+	Missense_Mutation	SNP	A	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr4:2934166A>G	uc003gfw.2	-	5	919	c.605T>C	c.(604-606)ATG>ACG	p.M202T	MFSD10_uc003gfv.2_5'Flank|MFSD10_uc003gfx.2_Missense_Mutation_p.M26T|MFSD10_uc003gfz.2_Missense_Mutation_p.M202T|MFSD10_uc003gfy.2_Intron|MFSD10_uc003gga.2_Missense_Mutation_p.M202T|MFSD10_uc003ggb.1_Missense_Mutation_p.M202T|MFSD10_uc003ggc.2_Missense_Mutation_p.M202T|C4orf10_uc003ggd.1_5'Flank|C4orf10_uc003gge.1_5'Flank	NM_001120	NP_001111	Q14728	MFS10_HUMAN	major facilitator superfamily domain containing	202	Helical; (Potential).				apoptosis	integral to membrane	tetracycline transporter activity				0				UCEC - Uterine corpus endometrioid carcinoma (64;0.163)		CCAGGGTGCCATTTCCAGGGG	0.632000													21	31					0	0	0.076483	0	0
SLCO6A1	133482	broad.mit.edu	37	5	101834204	101834204	+	Silent	SNP	C	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr5:101834204C>A	uc003knn.2	-	1	517	c.345G>T	c.(343-345)CTG>CTT	p.L115L	SLCO6A1_uc003kno.2_Silent_p.L115L|SLCO6A1_uc003knp.2_Silent_p.L115L|SLCO6A1_uc003knq.2_Silent_p.L115L	NM_173488	NP_775759	Q86UG4	SO6A1_HUMAN	solute carrier organic anion transporter family,	115	Helical; Name=1; (Potential).|Cys-rich.					integral to membrane|plasma membrane	transporter activity			ovary(3)|skin(3)|central_nervous_system(1)	7		all_cancers(142;8e-09)|all_epithelial(76;2.83e-12)|Prostate(80;0.00125)|Colorectal(57;0.00342)|Ovarian(225;0.024)|Lung NSC(167;0.0259)|all_lung(232;0.0323)		Epithelial(69;1.47e-15)|COAD - Colon adenocarcinoma(37;0.0113)		GACATATGAGCAGGATGCAGT	0.572000													33	37					1.80694e-10	1.9158e-10	0.041601	1	0
IL9	3578	broad.mit.edu	37	5	135228124	135228124	+	Missense_Mutation	SNP	T	C	C			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr5:135228124T>C	uc003lbb.1	-	5	402	c.391A>G	c.(391-393)ATT>GTT	p.I131V		NM_000590	NP_000581	P15248	IL9_HUMAN	interleukin 9 precursor	131					immune response|inflammatory response|positive regulation of cell proliferation|positive regulation of interleukin-5 biosynthetic process	extracellular space	cytokine activity|cytokine receptor binding|growth factor activity				0			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0233)			TTCTGGAAAATTTCCAGAAGA	0.368000													20	24					0	0	0.055883	0	0
SLC35A4	113829	broad.mit.edu	37	5	139947279	139947279	+	Silent	SNP	T	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr5:139947279T>A	uc003lgg.1	+	3	1253	c.525T>A	c.(523-525)GCT>GCA	p.A175A	SLC35A4_uc003lgh.1_Silent_p.A175A	NM_080670	NP_542401	Q96G79	S35A4_HUMAN	solute carrier family 35, member A4	175	Leu-rich.					Golgi membrane|integral to membrane	sugar:hydrogen symporter activity				0			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			CTCCAGCAGCTGCTGCCAGCC	0.622000													30	36					0	0	0.045705	0	0
TCP11	6954	broad.mit.edu	37	6	35088271	35088271	+	Missense_Mutation	SNP	T	C	C	rs62404564	byFrequency	TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr6:35088271T>C	uc003okd.2	-	7	1088	c.907A>G	c.(907-909)ATG>GTG	p.M303V	TCP11_uc003ojz.1_Missense_Mutation_p.M228V|TCP11_uc003oka.2_Missense_Mutation_p.M228V|TCP11_uc003okb.2_Missense_Mutation_p.M227V|TCP11_uc003okc.2_Missense_Mutation_p.M227V|TCP11_uc011dsu.1_Missense_Mutation_p.M285V|TCP11_uc011dsv.1_Missense_Mutation_p.M252V|TCP11_uc011dsw.1_Missense_Mutation_p.M257V	NM_001093728	NP_001087197	Q8WWU5	TCP11_HUMAN	t-complex 11 isoform 1	290					cell differentiation|multicellular organismal development|spermatogenesis	integral to membrane				ovary(3)|skin(2)	5						CACAGCACCATTGTGGGGCTG	0.557000													5	132					0	0	0.014758	0	0
TREM2	54209	broad.mit.edu	37	6	41129014	41129014	+	Silent	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr6:41129014C>T	uc003opy.2	-	2	480	c.378G>A	c.(376-378)GTG>GTA	p.V126V	TREM2_uc003opz.2_Silent_p.V156V|TREM2_uc010jxl.1_Silent_p.V156V	NM_018965	NP_061838	Q9NZC2	TREM2_HUMAN	triggering receptor expressed on myeloid cells 2	126	Extracellular (Potential).				axon guidance|humoral immune response	extracellular region|integral to membrane|plasma membrane	receptor activity			ovary(1)	1	Ovarian(28;0.0418)|Colorectal(47;0.196)					CCAGCACCTCCACCAGGACCT	0.612000													13	24					0	0	0.093190	0	0
TMEM120A	83862	broad.mit.edu	37	7	75617074	75617074	+	Missense_Mutation	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr7:75617074C>T	uc003ued.2	-	10	850	c.746G>A	c.(745-747)CGG>CAG	p.R249Q	TMEM120A_uc003uee.2_Silent_p.A187A|TMEM120A_uc003ueb.1_Missense_Mutation_p.R35Q|TMEM120A_uc003uec.2_Missense_Mutation_p.R153Q	NM_031925	NP_114131	Q9BXJ8	T120A_HUMAN	transmembrane protein 120A	249	Cytoplasmic (Potential).					integral to membrane					0						GCCCAGCGCCCGCAGGCGGTA	0.672000													7	24					0	0	0.047766	0	0
WDR91	29062	broad.mit.edu	37	7	134873248	134873248	+	Silent	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr7:134873248C>T	uc003vsp.2	-	13	1880	c.1818G>A	c.(1816-1818)GAG>GAA	p.E606E	WDR91_uc010lmq.2_Silent_p.E195E|WDR91_uc010lmr.2_Intron	NM_014149	NP_054868	A4D1P6	WDR91_HUMAN	WD repeat domain 91	606	WD 5.									breast(2)|ovary(1)|skin(1)	4						CAGAGTAGACCTCCCCGTAGT	0.502000													53	198					0	0	0.048971	0	0
PRKDC	5591	broad.mit.edu	37	8	48744423	48744423	+	Silent	SNP	G	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr8:48744423G>T	uc003xqi.2	-	61	8274	c.8217C>A	c.(8215-8217)CTC>CTA	p.L2739L	PRKDC_uc003xqj.2_Silent_p.L2739L|PRKDC_uc011ldh.1_Intron	NM_006904	NP_008835	P78527	PRKDC_HUMAN	protein kinase, DNA-activated, catalytic	2739	KIP-binding.				cellular response to insulin stimulus|double-strand break repair via nonhomologous end joining|peptidyl-serine phosphorylation|positive regulation of transcription from RNA polymerase II promoter	DNA-dependent protein kinase-DNA ligase 4 complex|transcription factor complex	ATP binding|DNA binding|DNA-dependent protein kinase activity|transcription factor binding			lung(12)|central_nervous_system(9)|ovary(6)|skin(4)|large_intestine(3)	34		all_cancers(86;0.0336)|all_epithelial(80;0.00111)|Lung NSC(129;0.00363)|all_lung(136;0.00391)				ACATCAAACTGAGCTTCTCCT	0.532000								NHEJ					67	100					2.26907e-38	2.52757e-38	0.048971	1	0
VCPIP1	80124	broad.mit.edu	37	8	67577113	67577113	+	Missense_Mutation	SNP	A	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr8:67577113A>G	uc003xwn.2	-	1	2340	c.2081T>C	c.(2080-2082)CTT>CCT	p.L694P	SGK3_uc003xwp.2_5'Flank|C8orf44_uc003xwo.1_5'Flank	NM_025054	NP_079330	Q96JH7	VCIP1_HUMAN	valosin containing protein (p97)/p47 complex	694					protein ubiquitination	endoplasmic reticulum|Golgi stack	ubiquitin-specific protease activity			lung(2)|ovary(2)|central_nervous_system(1)|breast(1)|skin(1)|kidney(1)	8		Lung NSC(129;0.142)|all_lung(136;0.227)	Epithelial(68;0.000771)|OV - Ovarian serous cystadenocarcinoma(28;0.00248)|all cancers(69;0.00296)|BRCA - Breast invasive adenocarcinoma(89;0.149)			CTGTCCAGTAAGAATAATTTT	0.373000													55	84					0	0	0.048971	0	0
TAF2	6873	broad.mit.edu	37	8	120816142	120816142	+	Missense_Mutation	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr8:120816142G>A	uc003you.2	-	5	806	c.536C>T	c.(535-537)TCT>TTT	p.S179F		NM_003184	NP_003175	Q6P1X5	TAF2_HUMAN	TBP-associated factor 2	179					G2/M transition of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter	transcription factor TFIID complex|transcription factor TFTC complex	metallopeptidase activity|protein binding|transcription regulatory region DNA binding|zinc ion binding			large_intestine(2)|ovary(2)|kidney(1)|skin(1)	6	Lung NSC(37;9.35e-07)|Ovarian(258;0.011)|Hepatocellular(40;0.161)		STAD - Stomach adenocarcinoma(47;0.00185)			ATACCCACAAGAGAAAACATG	0.333000													60	75					0	0	0.048971	0	0
LOC442421	442421	broad.mit.edu	37	9	66500841	66500841	+	RNA	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr9:66500841C>T	uc004aed.1	+	3		c.934C>T								Homo sapiens similar to prostaglandin E receptor 4, subtype EP4; PGE receptor, EP4 subtype; prostaglandin E2 receptor, mRNA (cDNA clone IMAGE:5288780).												0						CCACCTGGTGCCCAGGGCTCC	0.632000													3	26					0	0	0.021553	0	0
TNFSF15	9966	broad.mit.edu	37	9	117552848	117552848	+	Missense_Mutation	SNP	G	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr9:117552848G>A	uc004bjh.2	-	4	756	c.640C>T	c.(640-642)CTC>TTC	p.L214F	TNFSF15_uc004bjg.2_Missense_Mutation_p.L155F	NM_005118	NP_005109	O95150	TNF15_HUMAN	tumor necrosis factor (ligand) superfamily,	214	Extracellular (Potential).				activation of caspase activity|activation of NF-kappaB-inducing kinase activity|cytokine metabolic process|immune response	extracellular space|integral to plasma membrane	cytokine activity|tumor necrosis factor receptor binding				0						ATGGCTCCGAGGTAGATGGGC	0.493000													36	49					0	0	0.069456	0	0
PIP5KL1	138429	broad.mit.edu	37	9	130684238	130684238	+	Missense_Mutation	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr9:130684238C>T	uc011mao.1	-	10	1118	c.1073G>A	c.(1072-1074)CGG>CAG	p.R358Q	PIP5KL1_uc004bsu.2_Missense_Mutation_p.R155Q	NM_001135219	NP_001128691	Q5T9C9	PI5L1_HUMAN	phosphatidylinositol-4-phosphate 5-kinase-like 1	358	PIPK.					cytoplasm|membrane	1-phosphatidylinositol-4-phosphate 5-kinase activity|ATP binding			lung(1)|kidney(1)	2						GTGCTCCAGCCGCTTGCGGAG	0.687000											OREG0019512	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	1					0	0	0.009096	0	0
C9orf69	90120	broad.mit.edu	37	9	139008421	139008421	+	Missense_Mutation	SNP	C	T	T			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr9:139008421C>T	uc004cgx.3	-	2	851	c.400G>A	c.(400-402)GCC>ACC	p.A134T	C9orf69_uc004cgy.2_RNA	NM_152833	NP_690046			hypothetical protein LOC90120												0		Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;9.58e-07)|Epithelial(140;6.42e-06)		GTTCACCAGGCGGAAGTCCAC	0.657000													11	11					0	0	0.080935	0	0
TMEM27	57393	broad.mit.edu	37	X	15682860	15682860	+	Silent	SNP	A	G	G			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chrX:15682860A>G	uc004cxc.1	-	1	295	c.39T>C	c.(37-39)CAT>CAC	p.H13H		NM_020665	NP_065716	Q9HBJ8	TMM27_HUMAN	transmembrane protein 27 precursor	13					proteolysis	integral to membrane	metallopeptidase activity|peptidyl-dipeptidase activity			ovary(1)	1	Hepatocellular(33;0.183)					AGAGTTCAGCATGAATGGCAG	0.373000													25	8					0	0	0.076483	0	0
XKRX	402415	broad.mit.edu	37	X	100183205	100183205	+	Missense_Mutation	SNP	C	T	T	rs147872571	byFrequency	TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chrX:100183205C>T	uc004egn.2	-	1	694	c.89G>A	c.(88-90)CGA>CAA	p.R30Q	XKRX_uc011mre.1_5'UTR	NM_212559	NP_997724	Q6PP77	XKR2_HUMAN	XK, Kell blood group complex subunit-related,	30						integral to membrane|plasma membrane				breast(1)	1						AAAAGTAAATCGGGGGTTGGC	0.443000													4	80					0	0	0.009096	0	0
THOC2	57187	broad.mit.edu	37	X	122756985	122756985	+	Missense_Mutation	SNP	T	A	A			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chrX:122756985T>A	uc004etu.2	-	29	3685	c.3653A>T	c.(3652-3654)AAA>ATA	p.K1218I	THOC2_uc010nqt.1_5'Flank|THOC2_uc004etw.1_Missense_Mutation_p.K39I	NM_001081550	NP_001075019	Q8NI27	THOC2_HUMAN	THO complex 2	1218					intronless viral mRNA export from host nucleus|mRNA processing|RNA splicing	THO complex part of transcription export complex	protein binding|RNA binding			ovary(3)	3						TTCATCCGATTTAGATGCACT	0.403000													53	6					0	0	0.048971	0	0
PCDH17	27253	broad.mit.edu	37	13	58208351	58208351	+	Frame_Shift_Del	DEL	G	-	-			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr13:58208351delG	uc001vhq.1	+	1	2563	c.1671delG	c.(1669-1671)TCGfs	p.S557fs	PCDH17_uc010aec.1_Frame_Shift_Del_p.S557fs	NM_001040429	NP_001035519	O14917	PCD17_HUMAN	protocadherin 17 precursor	557	Extracellular (Potential).|Cadherin 5.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding|protein binding			ovary(3)|pancreas(2)|upper_aerodigestive_tract(1)|skin(1)	7		Lung NSC(96;0.027)|Prostate(109;0.0453)|Breast(118;0.128)|Hepatocellular(98;0.132)		GBM - Glioblastoma multiforme(99;1.06e-05)		CTAAGGACTCGGGGGCGCCCG	0.592													21	73	---	---	---	---					
MTHFD1	4522	broad.mit.edu	37	14	64914978	64914979	+	Frame_Shift_Del	DEL	AA	-	-			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr14:64914978_64914979delAA	uc001xhb.2	+	23	2609_2610	c.2222_2223delAA	c.(2221-2223)CAAfs	p.Q741fs	MTHFD1_uc010aqf.2_Frame_Shift_Del_p.Q797fs	NM_005956	NP_005947	P11586	C1TC_HUMAN	methylenetetrahydrofolate dehydrogenase 1	741	Formyltetrahydrofolate synthetase.				folic acid metabolic process|folic acid-containing compound biosynthetic process|histidine biosynthetic process|methionine biosynthetic process|one-carbon metabolic process|purine nucleotide biosynthetic process	cytosol|mitochondrion	ATP binding|formate-tetrahydrofolate ligase activity|methenyltetrahydrofolate cyclohydrolase activity|methylenetetrahydrofolate dehydrogenase (NADP+) activity|methylenetetrahydrofolate dehydrogenase|protein binding			ovary(2)	2				OV - Ovarian serous cystadenocarcinoma(108;8.7e-12)|all cancers(60;3.29e-11)|BRCA - Breast invasive adenocarcinoma(234;0.0488)	NADH(DB00157)|Tetrahydrofolic acid(DB00116)	TTGAAGAAACAAATTGAAAATG	0.401													16	32	---	---	---	---					
ZNF263	10127	broad.mit.edu	37	16	3339974	3339974	+	Frame_Shift_Del	DEL	T	-	-			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr16:3339974delT	uc002cuq.2	+	6	1800	c.1468delT	c.(1468-1470)TACfs	p.Y490fs	ZNF263_uc010uww.1_Frame_Shift_Del_p.Y138fs|ZNF263_uc002cur.2_Frame_Shift_Del_p.Y138fs	NM_005741	NP_005732	O14978	ZN263_HUMAN	zinc finger protein 263	490	C2H2-type 4.				viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			skin(3)|ovary(1)	4						GGAGAAGCCCTACAAGTGCCC	0.537													19	49	---	---	---	---					
KIDINS220	57498	broad.mit.edu	37	2	8872073	8872073	+	Frame_Shift_Del	DEL	A	-	-			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr2:8872073delA	uc002qzc.2	-	30	4275	c.4093delT	c.(4093-4095)TCCfs	p.S1365fs	KIDINS220_uc010yiv.1_Intron|KIDINS220_uc002qzd.2_Frame_Shift_Del_p.S1266fs|KIDINS220_uc002qzb.2_Frame_Shift_Del_p.S219fs	NM_020738	NP_065789	Q9ULH0	KDIS_HUMAN	kinase D-interacting substrate of 220 kDa	1365	Cytoplasmic (Potential).				activation of MAPKK activity|nerve growth factor receptor signaling pathway	cytosol|integral to membrane				ovary(3)|central_nervous_system(1)	4	all_hematologic(175;0.127)|Acute lymphoblastic leukemia(172;0.155)					GAATCCTGGGAATTGAGACTC	0.363													43	86	---	---	---	---					
ERC2	26059	broad.mit.edu	37	3	55733470	55733472	+	In_Frame_Del	DEL	TGG	-	-			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr3:55733470_55733472delTGG	uc003dhr.1	-	16	3037_3039	c.2781_2783delCCA	c.(2779-2784)CACCAT>CAT	p.927_928HH>H	ERC2_uc003dhq.1_RNA	NM_015576	NP_056391	O15083	ERC2_HUMAN	cytomatrix protein p110	927_928	Poly-His.					cell junction|cytoplasm|cytoskeleton|growth cone|presynaptic membrane|synaptosome	protein binding			ovary(2)	2				KIRC - Kidney renal clear cell carcinoma(284;0.0667)|Kidney(284;0.0873)|OV - Ovarian serous cystadenocarcinoma(275;0.219)		gtggtggtgatggtggtggtggt	0.389													8	369	---	---	---	---					
SH3BP2	6452	broad.mit.edu	37	4	2824661	2824661	+	Splice_Site	DEL	G	-	-			TCGA-A4-8311-01A-11D-2396-08	TCGA-A4-8311-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	ed5c8ff4-0d94-443d-9024-efdae20db5f3	ffccfd57-43fd-497f-b78d-a644b37173b2	g.chr4:2824661delG	uc003gfi.3	+	3	257	c.137_splice	c.e3-1	p.W46_splice	SH3BP2_uc010icn.2_Splice_Site_p.W46_splice|SH3BP2_uc011bvp.1_Splice_Site_p.W74_splice|SH3BP2_uc003gfj.3_Splice_Site_p.W103_splice|SH3BP2_uc003gfk.3_Splice_Site_p.W46_splice|SH3BP2_uc003gfl.3_Splice_Site	NM_001122681	NP_001116153	P78314	3BP2_HUMAN	SH3-domain binding protein 2 isoform a						signal transduction		SH3 domain binding|SH3/SH2 adaptor activity			central_nervous_system(1)	1				UCEC - Uterine corpus endometrioid carcinoma (64;0.164)		ACCTCCCACAGGGCCCCTGCG	0.622									Cherubism				13	18	---	---	---	---					
