Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PRAMEF11	440560	broad.mit.edu	37	1	12884981	12884981	+	Missense_Mutation	SNP	T	C	C	rs4989318	by1000genomes	TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr1:12884981T>C	uc001auk.2	-	4	1326	c.1130A>G	c.(1129-1131)CAG>CGG	p.Q377R		NM_001146344	NP_001139816	O60813	PRA11_HUMAN	PRAME family member 11	377											0						ATAACTTTCCTGCGGGGCAGG	0.507													6	86					0	0	0.029380	0	0
MST1P2	11209	broad.mit.edu	37	1	16974277	16974277	+	RNA	SNP	A	C	C	rs151151026	by1000genomes	TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr1:16974277A>C	uc009vow.2	+	5		c.1087A>C			MST1P2_uc010ocg.1_RNA|MST1P2_uc010och.1_Splice_Site|MST1P2_uc010oci.1_RNA|MST1P2_uc001azk.2_Splice_Site|MST1P2_uc001azl.3_RNA|MST1P2_uc009vox.2_Splice_Site|MST1P2_uc001azm.3_Splice_Site					Homo sapiens cDNA FLJ53774 complete cds, moderately similar to Hepatocyte growth factor-like protein precursor.												0						GGTCCATCTAAGGGTCCGAGG	0.657													6	25					0	0	0.058154	0	0
SLC4A8	9498	broad.mit.edu	37	12	51882579	51882579	+	Missense_Mutation	SNP	A	G	G	rs138940118		TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr12:51882579A>G	uc001rys.1	+	18	2561	c.2383A>G	c.(2383-2385)ATC>GTC	p.I795V	SLC4A8_uc001rym.2_Missense_Mutation_p.I742V|SLC4A8_uc001ryn.2_Missense_Mutation_p.I742V|SLC4A8_uc001ryo.2_Missense_Mutation_p.I742V|SLC4A8_uc010snj.1_Missense_Mutation_p.I822V|SLC4A8_uc001ryr.2_Missense_Mutation_p.I795V	NM_001039960	NP_001035049	Q2Y0W8	S4A8_HUMAN	solute carrier family 4, sodium bicarbonate	795	Helical; (Potential).				bicarbonate transport|sodium ion transport	integral to membrane|plasma membrane	inorganic anion exchanger activity			ovary(3)|pancreas(1)|skin(1)	5				BRCA - Breast invasive adenocarcinoma(357;0.15)		TCTCTGTACTATCTTGATATT	0.453													6	86					0	0	0.021553	0	0
RYR3	6263	broad.mit.edu	37	15	33962623	33962623	+	Missense_Mutation	SNP	T	G	G			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr15:33962623T>G	uc001zhi.2	+	38	5796	c.5726T>G	c.(5725-5727)GTT>GGT	p.V1909G	RYR3_uc010bar.2_Missense_Mutation_p.V1909G	NM_001036	NP_001027	Q15413	RYR3_HUMAN	ryanodine receptor 3	1909	4 X approximate repeats.|Cytoplasmic (By similarity).				cellular calcium ion homeostasis	integral to membrane	calcium ion binding|receptor activity|ryanodine-sensitive calcium-release channel activity			ovary(5)|central_nervous_system(4)|lung(1)	10		all_lung(180;7.18e-09)		all cancers(64;8.95e-12)|GBM - Glioblastoma multiforme(186;0.00109)|BRCA - Breast invasive adenocarcinoma(123;0.0363)		TTGCTAGGGGTTCCTTTggaa	0.398													10	19					0	0	0.024245	0	0
ITGAL	3683	broad.mit.edu	37	16	30500576	30500576	+	Missense_Mutation	SNP	G	A	A			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr16:30500576G>A	uc002dyi.3	+	11	1258	c.1082G>A	c.(1081-1083)GGC>GAC	p.G361D	ITGAL_uc002dyj.3_Missense_Mutation_p.G278D|ITGAL_uc010vev.1_Intron	NM_002209	NP_002200	P20701	ITAL_HUMAN	integrin alpha L isoform a precursor	361	FG-GAP 3.|Extracellular (Potential).				blood coagulation|heterophilic cell-cell adhesion|inflammatory response|integrin-mediated signaling pathway|leukocyte cell-cell adhesion|leukocyte migration|regulation of immune response|T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	integrin complex	cell adhesion molecule binding|receptor activity			ovary(3)|lung(3)|central_nervous_system(3)|breast(1)	10					Efalizumab(DB00095)	CCTGGGCAGGGCCATGCAGTC	0.622													20	54					0	0	0.055883	0	0
FLJ36000	284124	broad.mit.edu	37	17	21904069	21904069	+	RNA	SNP	C	G	G			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr17:21904069C>G	uc002gza.2	+	1		c.8C>G				NR_027084				Homo sapiens cDNA FLJ36000 fis, clone TESTI2015180.												0						tccgaggctccggcctgacct	0													3	11					0	0	0.004672	0	0
SLC25A39	51629	broad.mit.edu	37	17	42400903	42400903	+	Missense_Mutation	SNP	T	C	C			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr17:42400903T>C	uc002ign.2	-	2	182	c.28A>G	c.(28-30)AGC>GGC	p.S10G	SLC25A39_uc002igm.2_Missense_Mutation_p.S10G|SLC25A39_uc002igo.2_Missense_Mutation_p.S10G|SLC25A39_uc010wiw.1_Missense_Mutation_p.S10G|SLC25A39_uc010czu.2_Intron|SLC25A39_uc010wix.1_Missense_Mutation_p.S10G|SLC25A39_uc010wiy.1_Missense_Mutation_p.S10G	NM_001143780	NP_001137252	Q9BZJ4	S2539_HUMAN	solute carrier family 25, member 39 isoform a	10	Solcar 1.				heme biosynthetic process|transport	integral to membrane|mitochondrial inner membrane				upper_aerodigestive_tract(1)	1		Prostate(33;0.0233)		BRCA - Breast invasive adenocarcinoma(366;0.189)		TGGAGGGGGCTGATGCCCGCA	0.612													2	11					0	0	0.004672	0	0
FFAR3	2865	broad.mit.edu	37	19	35850686	35850686	+	Nonsense_Mutation	SNP	G	A	A			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr19:35850686G>A	uc002nzd.2	+	2	969	c.894G>A	c.(892-894)TGG>TGA	p.W298*	FFAR3_uc010xsu.1_Intron	NM_005304	NP_005295	O14843	FFAR3_HUMAN	free fatty acid receptor 3	298	Cytoplasmic (Potential).					integral to plasma membrane	G-protein coupled receptor activity|lipid binding				0	all_lung(56;9.78e-09)|Lung NSC(56;1.46e-08)|Esophageal squamous(110;0.162)		Epithelial(14;1.29e-19)|OV - Ovarian serous cystadenocarcinoma(14;4.63e-18)|all cancers(14;5.19e-17)|LUSC - Lung squamous cell carcinoma(66;0.0221)			GTGGGCTCTGGGGCCAGTGGC	0.587													7	48					0	0	0.038147	0	0
CCDC88A	55704	broad.mit.edu	37	2	55582839	55582839	+	Missense_Mutation	SNP	G	A	A			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr2:55582839G>A	uc002ryv.2	-	8	1518	c.676C>T	c.(676-678)CAT>TAT	p.H226Y	CCDC88A_uc010yoz.1_Missense_Mutation_p.H226Y|CCDC88A_uc010ypa.1_Missense_Mutation_p.H226Y|CCDC88A_uc010ypb.1_Missense_Mutation_p.H128Y	NM_001135597	NP_001129069	Q3V6T2	GRDN_HUMAN	coiled-coil domain containing 88A isoform 1	226	Potential.				activation of protein kinase B activity|cell migration|cellular membrane organization|DNA replication|lamellipodium assembly|microtubule cytoskeleton organization|regulation of actin cytoskeleton organization|regulation of cell proliferation|regulation of DNA replication|regulation of neuron projection development|TOR signaling cascade	cytoplasmic membrane-bounded vesicle|cytosol|endoplasmic reticulum|Golgi apparatus|lamellipodium|plasma membrane	actin binding|microtubule binding|phosphatidylinositol binding|protein homodimerization activity|protein kinase B binding			ovary(2)|skin(2)	4						GAAGAGGCATGGGGTAGAAAA	0.443													18	50					0	0	0.038395	0	0
LOC401010	401010	broad.mit.edu	37	2	132200345	132200345	+	Missense_Mutation	SNP	C	T	T	rs71428578	by1000genomes	TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr2:132200345C>T	uc002tst.2	-	1	2123	c.1657G>A	c.(1657-1659)GAG>AAG	p.E553K		NR_002826				SubName: Full=cDNA FLJ12694 fis, clone NT2RP1000358, highly similar to Homo sapiens mRNA; cDNA DKFZp564C186 (from clone DKFZp564C186);												0						CTGtcctcctcgccctcctcc	0.517													3	27					0	0	0.004672	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	T	T	rs121913500		TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr2:209113112C>T	uc002vcs.2	-	4	641	c.395G>A	c.(394-396)CGT>CAT	p.R132H	IDH1_uc002vct.2_Missense_Mutation_p.R132H|IDH1_uc002vcu.2_Missense_Mutation_p.R132H	NM_005896	NP_005887	O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132		Substrate.	R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2023)|p.R132C(344)|p.R132?(210)|p.R132G(117)|p.R132S(79)|p.R132L(58)|p.R132V(1)|p.G131_R132>VL(1)		central_nervous_system(2156)|haematopoietic_and_lymphoid_tissue(606)|bone(74)|thyroid(22)|large_intestine(4)|skin(2)|prostate(2)|autonomic_ganglia(1)|soft_tissue(1)	2868				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393			Mis		gliobastoma 								24	58					0	0	0.099896	0	0
POFUT2	23275	broad.mit.edu	37	21	46685545	46685545	+	Missense_Mutation	SNP	A	C	C			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr21:46685545A>C	uc002zhc.2	-	9	1167	c.1142T>G	c.(1141-1143)TTT>TGT	p.F381C	POFUT2_uc002zha.2_RNA|POFUT2_uc002zhb.2_RNA|POFUT2_uc002zhd.2_3'UTR	NM_133635	NP_598368	Q9Y2G5	OFUT2_HUMAN	protein O-fucosyltransferase 2 isoform C	381					fucose metabolic process	endoplasmic reticulum	peptide-O-fucosyltransferase activity				0				Colorectal(79;0.243)		GGTGCCAATAAAAAACCTGCA	0.498													12	28					0	0	0.080935	0	0
LOC96610	96610	broad.mit.edu	37	22	22664606	22664606	+	RNA	SNP	A	G	G			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr22:22664606A>G	uc011aim.1	+	31		c.2121A>G			LOC96610_uc011aiq.1_RNA					Parts of antibodies, mostly variable regions.												0						GTCTTCATGCAAACTTGGTAT	0.398													4	38					0	0	0.009096	0	0
MFNG	4242	broad.mit.edu	37	22	37882152	37882152	+	Silent	SNP	G	A	A			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr22:37882152G>A	uc003ass.1	-	1	234	c.64C>T	c.(64-66)CTG>TTG	p.L22L	MFNG_uc011ani.1_5'UTR|MFNG_uc011anj.1_Silent_p.L22L|CARD10_uc003ast.1_Intron	NM_002405	NP_002396	O00587	MFNG_HUMAN	O-fucosylpeptide	22	Helical; Signal-anchor for type II membrane protein; (Potential).				pattern specification process	extracellular space|integral to Golgi membrane	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity			lung(1)	1	Melanoma(58;0.0574)					CGCAGACACAGGAGCCCCATG	0.682													9	41					0	0	0.058154	0	0
DST	667	broad.mit.edu	37	6	56420389	56420389	+	Missense_Mutation	SNP	T	C	C			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr6:56420389T>C	uc003pdf.2	-	54	8561	c.8533A>G	c.(8533-8535)AGT>GGT	p.S2845G	DST_uc003pcz.3_Missense_Mutation_p.S2667G|DST_uc011dxj.1_Missense_Mutation_p.S2696G|DST_uc011dxk.1_Missense_Mutation_p.S2707G|DST_uc003pcy.3_Missense_Mutation_p.S2341G	NM_001144769	NP_001138241	Q03001	DYST_HUMAN	dystonin isoform 2	4753					cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere|Z disc	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein binding|protein C-terminus binding|protein homodimerization activity			ovary(7)|central_nervous_system(6)|upper_aerodigestive_tract(1)	14	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			TCCAAGTCACTCAGTTTATCA	0.453													7	63					0	0	0.029380	0	0
ABP1	26	broad.mit.edu	37	7	150555013	150555013	+	Silent	SNP	C	T	T			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr7:150555013C>T	uc003why.1	+	3	5673	c.1455C>T	c.(1453-1455)GTC>GTT	p.V485V	ABP1_uc003whz.1_Silent_p.V485V|ABP1_uc003wia.1_Silent_p.V485V	NM_001091	NP_001082	P19801	ABP1_HUMAN	amiloride binding protein 1 precursor	485					amine metabolic process	extracellular space|peroxisome	copper ion binding|diamine oxidase activity|heparin binding|histamine oxidase activity|methylputrescine oxidase activity|primary amine oxidase activity|propane-1,3-diamine oxidase activity|quinone binding			ovary(2)|breast(2)|skin(2)	6	all_neural(206;0.219)		OV - Ovarian serous cystadenocarcinoma(82;0.0121)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)	Amiloride(DB00594)|Spermine(DB00127)	CTGGCTACGTCCACGCCACCT	0.552													23	83					0	0	0.062417	0	0
TMEM68	137695	broad.mit.edu	37	8	56663637	56663637	+	Silent	SNP	G	A	A			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr8:56663637G>A	uc003xsg.1	-	3	642	c.573C>T	c.(571-573)CAC>CAT	p.H191H	TMEM68_uc003xsh.1_Silent_p.H191H	NM_152417	NP_689630	Q96MH6	TMM68_HUMAN	transmembrane protein 68	191						integral to membrane	acyltransferase activity			skin(1)	1			Epithelial(17;0.000361)|all cancers(17;0.00326)			TAGCTAACAAGTGGCCACTCC	0.418													20	86					0	0	0.055883	0	0
REXO1L1	254958	broad.mit.edu	37	8	86574480	86574480	+	Missense_Mutation	SNP	C	T	T			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr8:86574480C>T	uc011lfw.1	-	1	789	c.743G>A	c.(742-744)CGT>CAT	p.R248H		NM_172239	NP_758439	Q8IX06	GOR_HUMAN	exonuclease GOR	416	GOR1-125 epitope.					cytoplasm|nucleus	exonuclease activity|nucleic acid binding				0						GGTGCCACAACGGCAGCAGAC	0.682													4	40					0	0	0.009096	0	0
PHF16	9767	broad.mit.edu	37	X	46884202	46884202	+	Missense_Mutation	SNP	A	G	G			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chrX:46884202A>G	uc004dgx.2	+	5	412	c.361A>G	c.(361-363)ACA>GCA	p.T121A	PHF16_uc004dgy.2_Missense_Mutation_p.T121A	NM_001077445	NP_001070913	Q92613	JADE3_HUMAN	PHD finger protein 16	121					histone H3 acetylation|histone H4-K12 acetylation|histone H4-K5 acetylation|histone H4-K8 acetylation	histone acetyltransferase complex	zinc ion binding				0						CCCAGACACCACAGAGCCTGG	0.463													19	56					0	0	0.043863	0	0
USP11	8237	broad.mit.edu	37	X	47101902	47101902	+	Missense_Mutation	SNP	C	T	T			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chrX:47101902C>T	uc004dhp.2	+	11	1598	c.1598C>T	c.(1597-1599)ACG>ATG	p.T533M	USP11_uc004dhq.2_Missense_Mutation_p.T260M	NM_004651	NP_004642	P51784	UBP11_HUMAN	ubiquitin specific peptidase 11	533					protein deubiquitination|ubiquitin-dependent protein catabolic process	cytoplasm|nucleus	cysteine-type endopeptidase activity|protein binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity			ovary(1)|lung(1)|central_nervous_system(1)	3						TCCAAACACACGGGCATCTCG	0.567													12	45					0	0	0.093190	0	0
ZNF182	7569	broad.mit.edu	37	X	47836606	47836606	+	Missense_Mutation	SNP	C	T	T			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chrX:47836606C>T	uc004dir.2	-	7	1226	c.880G>A	c.(880-882)GAA>AAA	p.E294K	ZNF182_uc004dis.2_Missense_Mutation_p.E275K|ZNF182_uc004dit.2_Missense_Mutation_p.E294K|ZNF182_uc011mlu.1_Missense_Mutation_p.E274K	NM_006962	NP_008893	P17025	ZN182_HUMAN	zinc finger protein 21 isoform 1	294	C2H2-type 4.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(2)|lung(1)	3						TTTCCACATTCAGGACACTCA	0.398													36	87					0	0	0.069456	0	0
ATP11C	286410	broad.mit.edu	37	X	138886675	138886675	+	Silent	SNP	G	C	C			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chrX:138886675G>C	uc004faz.2	-	6	618	c.519C>G	c.(517-519)ACC>ACG	p.T173T	ATP11C_uc004fba.2_Silent_p.T173T	NM_173694	NP_775965	Q8NB49	AT11C_HUMAN	ATPase, class VI, type 11C isoform a	173	Cytoplasmic (Potential).				ATP biosynthetic process	integral to membrane|plasma membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			ovary(5)|large_intestine(3)	8	Acute lymphoblastic leukemia(192;0.000127)					TGACATAACAGGTTCCATCAG	0.393													74	182					0	0	0.048971	0	0
NF1	4763	broad.mit.edu	37	17	29556985	29556985	+	Frame_Shift_Del	DEL	C	-	-			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr17:29556985delC	uc002hgg.2	+	22	3316	c.2983delC	c.(2983-2985)CTGfs	p.L995fs	NF1_uc002hgh.2_Frame_Shift_Del_p.L995fs|NF1_uc010csn.1_Frame_Shift_Del_p.L855fs|NF1_uc002hgi.1_Frame_Shift_Del_p.L28fs	NM_001042492	NP_001035957	P21359	NF1_HUMAN	neurofibromin isoform 1	995					actin cytoskeleton organization|adrenal gland development|artery morphogenesis|camera-type eye morphogenesis|cerebral cortex development|collagen fibril organization|forebrain astrocyte development|forebrain morphogenesis|heart development|liver development|MAPKKK cascade|metanephros development|myelination in peripheral nervous system|negative regulation of cell migration|negative regulation of endothelial cell proliferation|negative regulation of MAP kinase activity|negative regulation of MAPKKK cascade|negative regulation of neuroblast proliferation|negative regulation of oligodendrocyte differentiation|negative regulation of transcription factor import into nucleus|osteoblast differentiation|phosphatidylinositol 3-kinase cascade|pigmentation|positive regulation of adenylate cyclase activity|positive regulation of neuron apoptosis|Ras protein signal transduction|regulation of blood vessel endothelial cell migration|regulation of bone resorption|response to hypoxia|smooth muscle tissue development|spinal cord development|sympathetic nervous system development|visual learning|wound healing	axon|cytoplasm|dendrite|intrinsic to internal side of plasma membrane|nucleus	protein binding|Ras GTPase activator activity	p.?(2)		soft_tissue(159)|central_nervous_system(56)|lung(28)|large_intestine(27)|haematopoietic_and_lymphoid_tissue(18)|ovary(18)|autonomic_ganglia(12)|breast(3)|skin(3)|stomach(2)|thyroid(1)|prostate(1)|kidney(1)|pancreas(1)	330		all_cancers(10;1.29e-12)|all_epithelial(10;0.00347)|all_hematologic(16;0.00556)|Acute lymphoblastic leukemia(14;0.00593)|Breast(31;0.014)|Myeloproliferative disorder(56;0.0255)|all_lung(9;0.0321)|Lung NSC(157;0.0659)		UCEC - Uterine corpus endometrioid carcinoma (4;4.38e-05)|all cancers(4;1.64e-26)|Epithelial(4;9.15e-23)|OV - Ovarian serous cystadenocarcinoma(4;3.58e-21)|GBM - Glioblastoma multiforme(4;0.00146)		GATGTTAAATCTGGTCAGGTA	0.348			D|Mis|N|F|S|O		neurofibroma|glioma	neurofibroma|glioma			Neurofibromatosis_type_1	TCGA GBM(6;<1E-08)|TSP Lung(7;0.0071)|TCGA Ovarian(3;0.0088)			41	120	---	---	---	---					
NKPD1	284353	broad.mit.edu	37	19	45655769	45655771	+	In_Frame_Del	DEL	CTG	-	-			TCGA-HT-8010-01A-11D-2395-08	TCGA-HT-8010-10A-01D-2396-08									Somatic	Phase_I	Capture				Illumina GAIIx	6fafd282-546e-4f61-b4f3-11fcc9afe5ef	75055f5e-3025-4fe5-9955-2be30e9ed69a	g.chr19:45655769_45655771delCTG	uc010xxi.1	-	4	1924_1926	c.1924_1926delCAG	c.(1924-1926)CAGdel	p.Q642del		NM_198478	NP_940880			NTPase, KAP family P-loop domain containing 1												0		Ovarian(192;0.0728)|all_neural(266;0.112)		OV - Ovarian serous cystadenocarcinoma(262;0.00863)|GBM - Glioblastoma multiforme(486;0.231)		CAAAGTCCCCCTGCTGCTGCTGC	0.704													2	4	---	---	---	---					
