Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KRTAP4-11	653240	broad.mit.edu	37	17	39274291	39274291	+	Missense_Mutation	SNP	T	C	C	rs149439944	by1000genomes	TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr17:39274291T>C	uc002hvz.3	-	0	316	c.277A>G	c.(277-279)Atg>Gtg	p.M93V		NM_033059	NP_149048	Q9BYQ6	KR411_HUMAN	Homo sapiens keratin associated protein 4-11 (KRTAP4-11), mRNA.	93	27 X 5 AA repeats of C-C-[GIKRQVHEL]- [SPTR]-[STVQRMC].					keratin filament		p.M93V(8)		endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|lung(8)|prostate(5)|skin(1)	33		Breast(137;0.000496)	STAD - Stomach adenocarcinoma(17;0.000371)			TGGCAGCACATAGACTGGCAG	0.662000														66			4		0	0	0.047766	0	0
TRIM52	84851	broad.mit.edu	37	5	180687083	180687083	+	Silent	SNP	G	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr5:180687083G>T	uc003mnp.3	-	0	1037	c.732C>A	c.(730-732)gcC>gcA	p.A244A	BC016291_uc003mnq.3_5'Flank	NM_032765	NP_116154	Q96A61	TRI52_HUMAN	Homo sapiens tripartite motif containing 52 (TRIM52), mRNA.	244						intracellular	zinc ion binding			endometrium(1)|large_intestine(2)|lung(3)|skin(1)|stomach(1)	8	all_cancers(89;8.79e-06)|all_epithelial(37;1.13e-06)|Renal(175;0.000159)|Lung NSC(126;0.00354)|all_lung(126;0.00609)|Breast(19;0.0654)	all_cancers(40;0.0106)|Medulloblastoma(196;0.0392)|all_neural(177;0.0529)|all_hematologic(541;0.0588)|all_lung(500;0.149)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)	all cancers(165;0.232)		CCACACAGATGGCCTCTTTGT	0.537000														102			33		5.8336e-16	6.73108e-16	0.015359	1	0
SCAF11	9169	broad.mit.edu	37	12	46320210	46320210	+	Missense_Mutation	SNP	G	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr12:46320210G>T	uc001rox.3	-	10	3561	c.3274C>A	c.(3274-3276)Cag>Aag	p.Q1092K	SCAF11_uc001row.3_Missense_Mutation_p.Q777K|SCAF11_uc001roy.1_Missense_Mutation_p.Q1166K	NM_004719	NP_004710	Q99590	SCAFB_HUMAN	Homo sapiens SR-related CTD-associated factor 11 (SCAF11), mRNA.	1092					spliceosome assembly	nucleus	protein binding|zinc ion binding	p.Q1092R(1)		breast(2)|central_nervous_system(1)|endometrium(2)|kidney(8)|large_intestine(17)|lung(25)|ovary(3)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(3)	69						TTTTCATTCTGATCTTTATAG	0.433000														102			20		1.50039e-11	1.6671e-11	0.012319	1	0
CSRP2BP	57325	broad.mit.edu	37	20	18142850	18142850	+	Missense_Mutation	SNP	C	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr20:18142850C>G	uc021wbb.1	+	4	1506	c.1069C>G	c.(1069-1071)Cca>Gca	p.P357A	CSRP2BP_uc002wqk.3_Missense_Mutation_p.P229A|CSRP2BP_uc010zru.2_Missense_Mutation_p.P228A	NM_020536	NP_065397	Q9H8E8	CSR2B_HUMAN	Homo sapiens CSRP2 binding protein (CSRP2BP), transcript variant 1, mRNA.	357					histone H3 acetylation	Ada2/Gcn5/Ada3 transcription activator complex|cytoplasm	LIM domain binding|N-acetyltransferase activity			NS(1)|breast(1)|endometrium(3)|kidney(3)|large_intestine(7)|lung(12)|ovary(2)|prostate(3)|skin(1)|stomach(1)	34						AGATCTGATTCCAGATGTGAT	0.458000														413			103		0	0	0.048971	0	0
AATK	9625	broad.mit.edu	37	17	79094952	79094952	+	Silent	SNP	A	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr17:79094952A>T	uc010dia.3	-	10	2864	c.2784T>A	c.(2782-2784)tcT>tcA	p.S928S	AATK_uc010dhz.3_Intron|AATK_uc021ueu.1_Silent_p.S825S	NM_001080395	NP_001073864	Q6ZMQ8	LMTK1_HUMAN	Homo sapiens apoptosis-associated tyrosine kinase (AATK), transcript variant 1, mRNA.	928						integral to membrane|mitochondrion|perinuclear region of cytoplasm	ATP binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			endometrium(2)|kidney(2)|lung(8)|ovary(3)|prostate(1)|stomach(4)|upper_aerodigestive_tract(1)	21	all_neural(118;0.101)		BRCA - Breast invasive adenocarcinoma(99;0.0228)|OV - Ovarian serous cystadenocarcinoma(97;0.0524)			GCTGCCCTCCAGAGGGGCCAG	0.647000														19			6		0	0	0.029380	0	0
EPS8	2059	broad.mit.edu	37	12	15784493	15784493	+	Missense_Mutation	SNP	C	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr12:15784493C>A	uc009zif.3	-	17	2021	c.1927G>T	c.(1927-1929)Gca>Tca	p.A643S	EPS8_uc001rdb.3_Missense_Mutation_p.A643S|EPS8_uc009zig.3_Missense_Mutation_p.A383S|EPS8_uc010shv.2_Missense_Mutation_p.A383S	NM_004447	NP_004438	Q12929	EPS8_HUMAN	Homo sapiens epidermal growth factor receptor pathway substrate 8 (EPS8), mRNA.	643	Pro-rich.				cell proliferation|epidermal growth factor receptor signaling pathway		SH3/SH2 adaptor activity			NS(1)|breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(9)|ovary(3)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	33		all_epithelial(100;1.87e-05)|Breast(259;0.000286)|Hepatocellular(102;0.244)		BRCA - Breast invasive adenocarcinoma(232;4.29e-05)|GBM - Glioblastoma multiforme(207;0.0264)		GGAACAGGTGCTGGAGTGGAA	0.547000														132			28		6.32553e-13	7.16098e-13	0.024334	1	0
SPOPL	339745	broad.mit.edu	37	2	139308572	139308572	+	Silent	SNP	A	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:139308572A>G	uc002tvh.3	+	3	700	c.300A>G	c.(298-300)gcA>gcG	p.A100A		NM_001001664	NP_001001664	Q6IQ16	SPOPL_HUMAN	Homo sapiens speckle-type POZ protein-like (SPOPL), mRNA.	100	MATH.					nucleus		p.R99P(1)|p.R99*(1)		breast(2)|cervix(2)|endometrium(2)|large_intestine(2)|lung(11)|skin(2)	21				BRCA - Breast invasive adenocarcinoma(221;0.0296)		AAGTTCGAGCAAAATTCAAAT	0.368000														76			27		0	0	0.037714	0	0
LRP4	4038	broad.mit.edu	37	11	46920187	46920187	+	Missense_Mutation	SNP	T	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr11:46920187T>A	uc001ndn.4	-	6	961	c.718A>T	c.(718-720)Agt>Tgt	p.S240C	LRP4_uc009ylh.2_Missense_Mutation_p.S191C	NM_002334	NP_002325	O75096	LRP4_HUMAN	Homo sapiens low density lipoprotein receptor-related protein 4 (LRP4), mRNA.	240	LDL-receptor class A 6.				Wnt receptor signaling pathway|endocytosis|negative regulation of canonical Wnt receptor signaling pathway	integral to membrane	calcium ion binding|receptor activity			breast(7)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(13)|lung(24)|ovary(3)|pancreas(2)|prostate(5)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)	70				Lung(87;0.159)		CACAGGCCACTGTCACACATG	0.567000														172			49		0	0	0.048971	0	0
CCKBR	887	broad.mit.edu	37	11	6281226	6281226	+	Missense_Mutation	SNP	G	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr11:6281226G>C	uc001mcp.3	+	0	323	c.68G>C	c.(67-69)cGc>cCc	p.R23P	CCKBR_uc001mcq.3_5'UTR|CCKBR_uc001mcr.3_Missense_Mutation_p.R23P|CCKBR_uc001mcs.3_Missense_Mutation_p.R23P	NM_176875	NP_795344	P32239	GASR_HUMAN	Homo sapiens cholecystokinin B receptor (CCKBR), mRNA.	23					activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger|cell proliferation|digestion|elevation of cytosolic calcium ion concentration|feeding behavior|positive regulation of cell proliferation|sensory perception		1-phosphatidylinositol-3-kinase regulator activity|gastrin receptor activity|phosphatidylinositol phospholipase C activity|type B gastrin/cholecystokinin receptor binding			NS(2)|breast(2)|endometrium(4)|kidney(13)|large_intestine(10)|lung(22)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	61		Medulloblastoma(188;0.00263)|all_neural(188;0.026)|Breast(177;0.029)		Epithelial(150;2.62e-08)|BRCA - Breast invasive adenocarcinoma(625;0.139)	Pentagastrin(DB00183)	TCCCTGTGCCGCCCGGGGGCG	0.716000														17			6		0	0	0.029380	0	0
KYNU	8942	broad.mit.edu	37	2	143718222	143718222	+	Missense_Mutation	SNP	C	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:143718222C>G	uc010fnm.3	+	8	828	c.612C>G	c.(610-612)atC>atG	p.I204M	KYNU_uc002tvk.3_Missense_Mutation_p.I204M|KYNU_uc002tvl.3_Missense_Mutation_p.I204M	NM_001199241	NP_001186170	Q16719	KYNU_HUMAN	Homo sapiens kynureninase (KYNU), transcript variant 3, mRNA.	204					NAD biosynthetic process|anthranilate metabolic process|quinolinate biosynthetic process|response to interferon-gamma|response to vitamin B6	cytosol|mitochondrion|soluble fraction	kynureninase activity|protein homodimerization activity			large_intestine(10)|liver(1)|lung(18)|prostate(3)|skin(4)	36				BRCA - Breast invasive adenocarcinoma(221;0.072)	L-Alanine(DB00160)|Pyridoxal Phosphate(DB00114)	TAGAGGATATCCTTGAAGTAA	0.368000														68			12		0	0	0.016723	0	0
TEP1	7011	broad.mit.edu	37	14	20857434	20857434	+	Missense_Mutation	SNP	C	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr14:20857434C>T	uc001vxe.3	-	16	2528	c.2488G>A	c.(2488-2490)Gat>Aat	p.D830N	TEP1_uc010ahk.3_Missense_Mutation_p.D180N|TEP1_uc010tlf.1_Non-coding_Transcript|TEP1_uc010tlg.1_Missense_Mutation_p.D722N	NM_007110	NP_009041	Q99973	TEP1_HUMAN	Homo sapiens telomerase-associated protein 1 (TEP1), mRNA.	830					telomere maintenance via recombination	chromosome, telomeric region|cytoplasm|nuclear matrix|soluble fraction|telomerase holoenzyme complex	ATP binding|RNA binding			NS(4)|breast(1)|central_nervous_system(4)|endometrium(10)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(9)|lung(48)|ovary(7)|pancreas(1)|prostate(2)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	96	all_cancers(95;0.00123)	all_lung(585;0.235)	Epithelial(56;7.42e-08)|all cancers(55;6.46e-07)	GBM - Glioblastoma multiforme(265;0.028)|READ - Rectum adenocarcinoma(17;0.233)		AGTGTCACATCATTGGGATTC	0.418000														43			15		0	0	0.028581	0	0
ATP10A	57194	broad.mit.edu	37	15	25959389	25959389	+	Splice_Site	SNP	C	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr15:25959389C>G	uc010ayu.3	-	10	1883	c.1777_splice	c.e10-1	p.V593_splice		NM_024490	NP_077816	O60312	AT10A_HUMAN	Homo sapiens ATPase, class V, type 10A (ATP10A), mRNA.	593					ATP biosynthetic process|regulation of cell shape	integral to membrane|plasma membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			NS(1)|breast(2)|endometrium(8)|kidney(2)|large_intestine(33)|liver(1)|lung(41)|ovary(3)|pancreas(2)|skin(5)|upper_aerodigestive_tract(3)|urinary_tract(2)	103		all_cancers(20;5.16e-25)|all_lung(180;1.51e-14)|Acute lymphoblastic leukemia(1;2.53e-05)|all_hematologic(1;0.000267)|Breast(32;0.00125)		all cancers(64;9.48e-07)|Epithelial(43;1.69e-06)|BRCA - Breast invasive adenocarcinoma(123;0.0252)|Lung(196;0.244)		TCACCCTCACCTGCAAGAGAA	0.582000														33			5		0	0	0.014758	0	0
LY75-CD302	100526664	broad.mit.edu	37	2	160665004	160665004	+	Missense_Mutation	SNP	T	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:160665004T>C	uc002ubb.4	-	32	4852	c.4778A>G	c.(4777-4779)aAc>aGc	p.N1593S	LY75-CD302_uc010fos.3_Missense_Mutation_p.N1593S|LY75-CD302_uc002ubc.4_Missense_Mutation_p.N1593S	NM_001198759	NP_001185688	O60449	LY75_HUMAN	Homo sapiens LY75-CD302 readthrough (LY75-CD302), transcript variant 1, mRNA.	1593	C-type lectin 10.				endocytosis|immune response|inflammatory response	integral to plasma membrane	receptor activity|sugar binding										CATGGTAATGTTATTATTTTC	0.338000														52			17		0	0	0.049695	0	0
HM13	81502	broad.mit.edu	37	20	30137040	30137040	+	Missense_Mutation	SNP	G	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr20:30137040G>A	uc002wwc.3	+	5	685	c.571G>A	c.(571-573)Gcc>Acc	p.A191T	HM13_uc002wwd.3_Missense_Mutation_p.A191T|HM13_uc002wwe.3_Missense_Mutation_p.A191T|HM13_uc002wwf.3_Missense_Mutation_p.A67T	NM_178581	NP_848696	Q8TCT9	HM13_HUMAN	Homo sapiens histocompatibility (minor) 13 (HM13), transcript variant 3, mRNA.	191					membrane protein proteolysis	cell surface|endoplasmic reticulum membrane|integral to membrane|plasma membrane	aspartic-type endopeptidase activity|protein binding			breast(1)|endometrium(2)|large_intestine(2)|lung(4)|prostate(1)|skin(1)|urinary_tract(1)	12	all_cancers(5;3.44e-05)|Lung NSC(7;4.38e-06)|all_lung(7;7.65e-06)|all_hematologic(12;0.158)|Ovarian(7;0.198)		all cancers(5;0.000479)|Colorectal(19;0.00202)|COAD - Colon adenocarcinoma(19;0.0264)			TTTTGGCCTGGCCTTCTCCCT	0.567000														254			54		0	0	0.048971	0	0
TPTE2P6	374491	broad.mit.edu	37	13	25171595	25171595	+	RNA	SNP	T	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr13:25171595T>C	uc001upm.3	+	12		c.1491T>C			TPTE2P6_uc001upn.3_Non-coding_Transcript|TPTE2P6_uc001upo.3_Non-coding_Transcript					Homo sapiens transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 6 (TPTE2P6), non-coding RNA.																		TCCACCAGAATTTGCCGTGGA	0.348000														49			14		0	0	0.043863	0	0
MST1P2	11209	broad.mit.edu	37	1	16975947	16975947	+	RNA	SNP	C	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr1:16975947C>T	uc010och.2	+	10		c.1969C>T			MST1P2_uc009vox.3_Non-coding_Transcript|MST1P2_uc001azm.4_Non-coding_Transcript					Homo sapiens macrophage stimulating 1 (hepatocyte growth factor-like) pseudogene 2 (MST1P2), non-coding RNA.																		AGAGCCAGGCCTACAGCGGGT	0.577000														35			3		0	0	0.004672	0	0
ALDH3A2	224	broad.mit.edu	37	17	19575183	19575183	+	Missense_Mutation	SNP	T	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr17:19575183T>A	uc002gwa.1	+	8	1578	c.1357T>A	c.(1357-1359)Ttt>Att	p.F453I	ALDH3A2_uc002gwb.1_Missense_Mutation_p.F453I|ALDH3A2_uc010cqr.1_Missense_Mutation_p.F260I|ALDH3A2_uc002gwd.1_Missense_Mutation_p.F260I	NM_001031806	NP_001026976	P51648	AL3A2_HUMAN	Homo sapiens aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), transcript variant 1, mRNA.	453					cellular aldehyde metabolic process|central nervous system development|epidermis development|lipid metabolic process|peripheral nervous system development	endoplasmic reticulum membrane|integral to membrane	3-chloroallyl aldehyde dehydrogenase activity|aldehyde dehydrogenase|aldehyde dehydrogenase (NAD) activity			endometrium(1)|kidney(1)|large_intestine(5)|liver(1)|lung(2)|ovary(2)|prostate(1)	13	all_cancers(12;1.39e-05)|all_epithelial(12;0.00158)|Breast(13;0.245)				NADH(DB00157)	TTGGGGAAAATTTTTTCTCTT	0.423000														190			50		0	0	0.048971	0	0
CCNG2	901	broad.mit.edu	37	4	78082688	78082688	+	Nonsense_Mutation	SNP	C	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr4:78082688C>T	uc003hkq.4	+	4	886	c.583C>T	c.(583-585)Cga>Tga	p.R195*	CCNG2_uc003hkn.4_Nonsense_Mutation_p.R195*|CCNG2_uc011ccc.1_Nonsense_Mutation_p.R195*|CCNG2_uc003hkp.4_Nonsense_Mutation_p.R195*	NM_004354	NP_004345	Q16589	CCNG2_HUMAN	Homo sapiens cyclin G2 (CCNG2), mRNA.	195					cell cycle checkpoint|cell division|mitosis	cytoplasm				breast(1)|kidney(2)|lung(4)|ovary(2)|upper_aerodigestive_tract(1)	10						TTGCAACTGCCGACTCATCTT	0.294000														37			7		0	0	0.047766	0	0
PRPF6	24148	broad.mit.edu	37	20	62648174	62648174	+	Silent	SNP	T	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr20:62648174T>C	uc002yho.3	+	11	1791	c.1623T>C	c.(1621-1623)caT>caC	p.H541H	PRPF6_uc002yhp.3_Silent_p.H541H	NM_012469	NP_036601	O94906	PRP6_HUMAN	Homo sapiens PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) (PRPF6), mRNA.	541					assembly of spliceosomal tri-snRNP|positive regulation of transcription from RNA polymerase II promoter|spliceosome assembly	U4/U6 snRNP|U4/U6 x U5 tri-snRNP complex|U5 snRNP|catalytic step 2 spliceosome|nucleoplasm	androgen receptor binding|ribonucleoprotein binding|transcription coactivator activity			breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(14)|ovary(2)|pancreas(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	35	all_cancers(38;6.47e-12)|all_epithelial(29;1.26e-13)|Lung NSC(23;9.37e-10)|all_lung(23;3.23e-09)					ATCGGAAGCATACCTGGATGG	0.552000														55			10		0	0	0.010729	0	0
DOCK1	1793	broad.mit.edu	37	10	129245700	129245700	+	Missense_Mutation	SNP	T	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr10:129245700T>A	uc010qun.2	+	50	5520	c.5456T>A	c.(5455-5457)gTc>gAc	p.V1819D	DOCK1_uc001ljt.3_Missense_Mutation_p.V1798D|DOCK1_uc009yaq.3_Nonsense_Mutation_p.C797*|DOCK1_uc001ljw.1_5'Flank	NM_001380	NP_001371	Q14185	DOCK1_HUMAN	Homo sapiens dedicator of cytokinesis 1 (DOCK1), mRNA.	1798	Interaction with NCK2 second and third SH3 domain (minor).				apoptosis|axon guidance|blood coagulation|integrin-mediated signaling pathway|phagocytosis, engulfment|small GTPase mediated signal transduction	cytosol|membrane	GTP binding|GTPase activator activity|GTPase binding|SH3 domain binding|guanyl-nucleotide exchange factor activity			NS(2)|breast(1)|central_nervous_system(7)|endometrium(13)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(10)|lung(15)|ovary(4)|prostate(3)|stomach(2)|upper_aerodigestive_tract(5)|urinary_tract(1)	72		all_epithelial(44;2.3e-07)|all_lung(145;0.00466)|Lung NSC(174;0.00685)|Colorectal(57;0.0107)|Renal(717;0.0113)|Breast(234;0.0492)|all_neural(114;0.108)|all_hematologic(284;0.14)		BRCA - Breast invasive adenocarcinoma(275;0.0221)|Colorectal(40;0.115)		GTGGCCGATGTCCCACCCCCT	0.592000														15			4		0	0	0.009096	0	0
ANKS6	203286	broad.mit.edu	37	9	101533259	101533259	+	Missense_Mutation	SNP	A	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr9:101533259A>T	uc004ayu.3	-	9	1912	c.1891T>A	c.(1891-1893)Ttc>Atc	p.F631I	ANKS6_uc004ayv.2_Missense_Mutation_p.F93I|ANKS6_uc004ayx.2_Non-coding_Transcript|ANKS6_uc004ayy.2_Non-coding_Transcript|ANKS6_uc004ayt.3_Missense_Mutation_p.F330I	NM_173551	NP_775822	Q68DC2	ANKS6_HUMAN	Homo sapiens ankyrin repeat and sterile alpha motif domain containing 6 (ANKS6), mRNA.	631	Ser-rich.									endometrium(3)|large_intestine(6)|lung(6)|ovary(2)|pancreas(1)|prostate(2)|skin(1)	21		Acute lymphoblastic leukemia(62;0.0527)				GAGTGGTTGAAGTTTCCAGAA	0.582000														35			12		0	0	0.010729	0	0
FTMT	94033	broad.mit.edu	37	5	121188229	121188229	+	Missense_Mutation	SNP	G	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr5:121188229G>A	uc003kss.3	+	0	580	c.571G>A	c.(571-573)Gat>Aat	p.D191N		NM_177478	NP_803431	Q8N4E7	FTMT_HUMAN	Homo sapiens ferritin mitochondrial (FTMT), nuclear gene encoding mitochondrial protein, mRNA.	191	Ferritin-like diiron.				cellular iron ion homeostasis|iron ion transport|positive regulation of cell proliferation|positive regulation of lyase activity|positive regulation of oxidoreductase activity|positive regulation of transferase activity	mitochondrion	ferric iron binding|ferroxidase activity			NS(1)|breast(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(15)|ovary(1)|skin(4)|upper_aerodigestive_tract(1)	33		all_cancers(142;0.0124)|Prostate(80;0.0322)	KIRC - Kidney renal clear cell carcinoma(527;0.206)	Epithelial(69;0.000171)|OV - Ovarian serous cystadenocarcinoma(64;0.000188)|all cancers(49;0.0027)		CCATTTGTGCGATTTCCTGGA	0.507000														138			46		0	0	0.048971	0	0
CCDC75	253635	broad.mit.edu	37	2	37319335	37319335	+	Missense_Mutation	SNP	A	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:37319335A>C	uc010ezz.3	+	5	610	c.465A>C	c.(463-465)gaA>gaC	p.E155D	CCDC75_uc002rpr.4_Missense_Mutation_p.E52D	NM_174931	NP_777591	Q8N954	CCD75_HUMAN	Homo sapiens coiled-coil domain containing 75 (CCDC75), mRNA.	155						intracellular	nucleic acid binding			endometrium(2)|kidney(3)|large_intestine(1)|urinary_tract(1)	7		all_hematologic(82;0.21)				AGCAAGATGAAATGAAGCTAG	0.363000														17			8		0	0	0.047766	0	0
PARD6B	84612	broad.mit.edu	37	20	49367023	49367023	+	Nonstop_Mutation	SNP	T	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr20:49367023T>C	uc002xvo.3	+	2	1360	c.1117T>C	c.(1117-1119)Tga>Cga	p.*373R		NM_032521	NP_115910	Q9BYG5	PAR6B_HUMAN	Homo sapiens par-6 partitioning defective 6 homolog beta (C. elegans) (PARD6B), mRNA.	0					axonogenesis|cell cycle|cell division|establishment or maintenance of cell polarity|protein complex assembly|regulation of cell migration|tight junction assembly	cytosol|tight junction	protein binding			NS(1)|breast(1)|endometrium(1)|kidney(4)|lung(3)|urinary_tract(1)	11						CATAACATTATGAAACCGTGG	0.398000														48			10		0	0	0.006214	0	0
PRSS55	203074	broad.mit.edu	37	8	10388999	10388999	+	Missense_Mutation	SNP	C	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr8:10388999C>G	uc003wta.3	+	2	582	c.542C>G	c.(541-543)cCc>cGc	p.P181R	AK307207_uc010lru.3_Intron|PRSS55_uc022art.1_Missense_Mutation_p.P181R|PRSS55_uc003wtb.3_Non-coding_Transcript	NM_198464	NP_940866	Q6UWB4	PRS55_HUMAN	Homo sapiens protease, serine, 55 (PRSS55), transcript variant 1, mRNA.	181	Peptidase S1.				proteolysis	integral to membrane	serine-type endopeptidase activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(9)|lung(14)|ovary(1)|prostate(1)|skin(1)	31						CCCACGCAGCCCGGCCCTGCC	0.587000														82			10		0	0	0.008291	0	0
SYNPO2	171024	broad.mit.edu	37	4	119952706	119952706	+	Missense_Mutation	SNP	A	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr4:119952706A>T	uc010inb.3	+	3	2972	c.2776A>T	c.(2776-2778)Aat>Tat	p.N926Y	SYNPO2_uc010ina.3_Missense_Mutation_p.N926Y|SYNPO2_uc003icm.4_Missense_Mutation_p.N926Y|SYNPO2_uc011cgh.2_Intron|SYNPO2_uc010inc.3_Missense_Mutation_p.N854Y|SYNPO2_uc021xrd.1_5'Flank	NM_133477	NP_597734	Q9UMS6	SYNP2_HUMAN	Homo sapiens synaptopodin 2 (SYNPO2), transcript variant 1, mRNA.	926						Z disc|nucleus	14-3-3 protein binding|actin binding|muscle alpha-actinin binding			breast(3)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(20)|lung(18)|ovary(2)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	64						TGTGGCCTATAATCCTATCCA	0.572000														65			26		0	0	0.030593	0	0
INHBC	3626	broad.mit.edu	37	12	57828750	57828750	+	Silent	SNP	A	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr12:57828750A>C	uc001snv.1	+	0	208	c.81A>C	c.(79-81)ccA>ccC	p.P27P		NM_005538	NP_005529	P55103	INHBC_HUMAN	Homo sapiens inhibin, beta C (INHBC), mRNA.	27					growth	extracellular region	growth factor activity|hormone activity|transforming growth factor beta receptor binding			breast(2)|endometrium(1)|large_intestine(6)|liver(2)|lung(4)|prostate(1)	16						GTCAGTGTCCAGCATGTGGGG	0.607000														74			15		0	0	0.020292	0	0
COL22A1	169044	broad.mit.edu	37	8	139790649	139790649	+	Splice_Site	SNP	C	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr8:139790649C>T	uc003yvd.3	-	15	2152	c.1705_splice	c.e15-1	p.G569_splice		NM_152888	NP_690848	Q8NFW1	COMA1_HUMAN	Homo sapiens collagen, type XXII, alpha 1 (COL22A1), mRNA.	569	Collagen-like 3.|Gly-rich.|Pro-rich.				cell adhesion	collagen|cytoplasm	structural molecule activity			breast(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(2)|kidney(14)|large_intestine(29)|lung(107)|ovary(13)|pancreas(1)|prostate(3)|skin(12)|upper_aerodigestive_tract(15)|urinary_tract(4)	211	all_epithelial(106;1.55e-12)|Lung NSC(106;1.67e-05)|all_lung(105;3.39e-05)|Ovarian(258;0.00672)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0517)			CCTTGGGGCCCCTGCAGAAGA	0.572000										HNSCC(7;0.00092)				34			17		0	0	0.043863	0	0
NCOA1	8648	broad.mit.edu	37	2	24991159	24991159	+	Silent	SNP	C	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:24991159C>T	uc002rfk.3	+	20	4484	c.4225C>T	c.(4225-4227)Ctg>Ttg	p.L1409L	NCOA1_uc010eye.3_3'UTR|NCOA1_uc002rfi.3_3'UTR|NCOA1_uc002rfj.3_3'UTR|NCOA1_uc002rfl.3_Silent_p.L1408L|NCOA1_uc010eyf.3_3'UTR	NM_003743	NP_003734	Q15788	NCOA1_HUMAN	Homo sapiens nuclear receptor coactivator 1 (NCOA1), transcript variant 1, mRNA.	1409									PAX3/NCOA1(8)	breast(3)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(13)|lung(26)|ovary(2)|prostate(1)|skin(1)|urinary_tract(1)	53	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					GGACCCTTACCTGAACCAGCC	0.532000			T	PAX3	alveolar rhadomyosarcoma									99			25		0	0	0.021523	0	0
ALDH1L2	160428	broad.mit.edu	37	12	105428135	105428135	+	Missense_Mutation	SNP	A	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr12:105428135A>C	uc001tlc.3	-	18	2314	c.2187T>G	c.(2185-2187)atT>atG	p.I729M	ALDH1L2_uc009zuo.3_Missense_Mutation_p.I184M|ALDH1L2_uc009zup.3_Non-coding_Transcript	NM_001034173	NP_001029345	Q3SY69	AL1L2_HUMAN	Homo sapiens aldehyde dehydrogenase 1 family, member L2 (ALDH1L2), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.	729	Aldehyde dehydrogenase.				10-formyltetrahydrofolate catabolic process|biosynthetic process	mitochondrion	acyl carrier activity|cofactor binding|formyltetrahydrofolate dehydrogenase activity|hydroxymethyl-, formyl- and related transferase activity|methyltransferase activity|phosphopantetheine binding			breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(13)|prostate(2)|skin(3)|stomach(2)	35						GCCCAGCAGCAATACAGTTCT	0.418000														59			13		0	0	0.033300	0	0
RELN	5649	broad.mit.edu	37	7	103234873	103234873	+	Silent	SNP	G	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr7:103234873G>C	uc022ajr.1	-	25	3766	c.3606C>G	c.(3604-3606)ccC>ccG	p.P1202P	RELN_uc022ajq.1_Silent_p.P1202P|RELN_uc010liz.3_Silent_p.P1202P	NM_005045	NP_005036	P78509	RELN_HUMAN	Homo sapiens reelin (RELN), transcript variant 1, mRNA.	1202					axon guidance|cell adhesion|cerebral cortex tangential migration|glial cell differentiation|neuron migration|peptidyl-tyrosine phosphorylation|positive regulation of protein kinase activity|positive regulation of small GTPase mediated signal transduction|response to pain|spinal cord patterning	cytoplasm|dendrite|extracellular space|proteinaceous extracellular matrix	metal ion binding|protein serine/threonine/tyrosine kinase activity|serine-type peptidase activity			NS(3)|breast(8)|central_nervous_system(3)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(4)|kidney(6)|large_intestine(43)|lung(101)|ovary(9)|pancreas(2)|prostate(4)|skin(14)|stomach(2)|upper_aerodigestive_tract(12)|urinary_tract(2)	227				COAD - Colon adenocarcinoma(1;8.98e-05)|Colorectal(1;0.00184)		CTGAGAACACGGGCTGCCACC	0.488000														269			15		0	0	0.049695	0	0
ENGASE	64772	broad.mit.edu	37	17	77079593	77079593	+	Missense_Mutation	SNP	C	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr17:77079593C>G	uc002jwv.3	+	8	1180	c.1172C>G	c.(1171-1173)cCc>cGc	p.P391R	ENGASE_uc002jww.3_Missense_Mutation_p.P97R	NM_001042573	NP_001036038	Q8NFI3	ENASE_HUMAN	Homo sapiens endo-beta-N-acetylglucosaminidase (ENGASE), mRNA.	391						cytosol	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity			breast(2)|endometrium(4)|large_intestine(1)|lung(15)|prostate(2)|skin(1)	25						CGTTATCTGCCCACACATAGC	0.617000														54			10		0	0	0.006214	0	0
ALG2	85365	broad.mit.edu	37	9	101980774	101980774	+	Silent	SNP	G	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr9:101980774G>A	uc004azf.3	-	1	763	c.693C>T	c.(691-693)atC>atT	p.I231I	ALG2_uc004azg.3_Silent_p.I138I	NM_033087	NP_149078	Q9H553	ALG2_HUMAN	Homo sapiens asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) (ALG2), transcript variant 1, mRNA.	231					dolichol-linked oligosaccharide biosynthetic process|post-translational protein modification|protein N-linked glycosylation via asparagine|protein glycosylation in endoplasmic reticulum|response to calcium ion	endoplasmic reticulum membrane|integral to membrane|membrane fraction|nucleus|perinuclear region of cytoplasm	alpha-1,3-mannosyltransferase activity|calcium-dependent protein binding|glycolipid 3-alpha-mannosyltransferase activity|protein N-terminus binding|protein anchor|protein heterodimerization activity			breast(1)|endometrium(1)|kidney(2)|large_intestine(3)|lung(11)|ovary(2)|prostate(2)	22		Acute lymphoblastic leukemia(62;0.0559)				CGTATCTGTTGATGGAGAGCA	0.463000														65			25		0	0	0.016522	0	0
ANKRD32	84250	broad.mit.edu	37	5	94030836	94030836	+	Missense_Mutation	SNP	C	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr5:94030836C>A	uc003kkr.4	+	20	3076	c.2996C>A	c.(2995-2997)aCc>aAc	p.T999N	ANKRD32_uc003kks.3_Missense_Mutation_p.T363N	NM_032290	NP_115666	Q9BQI6	ANR32_HUMAN	Homo sapiens ankyrin repeat domain 32 (ANKRD32), mRNA.	999										NS(1)|breast(2)|endometrium(2)|large_intestine(1)|lung(3)|ovary(2)|prostate(1)|skin(1)	13		all_cancers(142;1.51e-09)|all_epithelial(76;4.68e-12)|all_lung(232;5.94e-05)|Ovarian(174;0.000953)|Lung NSC(167;0.00105)|Colorectal(57;0.122)|Lung SC(612;0.152)		all cancers(79;3.88e-18)		CATAAAGAAACCACCAGTGTT	0.348000														40			10		4.3838e-07	4.78233e-07	0.016723	1	0
DDX56	54606	broad.mit.edu	37	7	44607797	44607797	+	Missense_Mutation	SNP	T	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr7:44607797T>G	uc003tlg.3	-	11	2052	c.1409A>C	c.(1408-1410)gAc>gCc	p.D470A	DDX56_uc003tlh.3_Non-coding_Transcript|DDX56_uc010kyg.3_Missense_Mutation_p.D430A	NM_019082	NP_061955	Q9NY93	DDX56_HUMAN	Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 (DDX56), mRNA.	470					rRNA processing	nucleolus	ATP binding|ATP-dependent RNA helicase activity|RNA binding|identical protein binding			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(5)|lung(5)|upper_aerodigestive_tract(1)	16						CAGCTGGAGGTCCCTAGGGTT	0.567000														35			7		0	0	0.038147	0	0
RNF6	6049	broad.mit.edu	37	13	26788332	26788332	+	Missense_Mutation	SNP	T	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr13:26788332T>A	uc001uqo.3	-	4	2032	c.1687A>T	c.(1687-1689)Agt>Tgt	p.S563C	RNF6_uc001uqn.1_Intron|RNF6_uc001uqp.3_Missense_Mutation_p.S563C|RNF6_uc001uqq.3_Missense_Mutation_p.S563C|RNF6_uc010tdk.2_Missense_Mutation_p.S207C	NM_183044	NP_898865	Q9Y252	RNF6_HUMAN	Homo sapiens ring finger protein (C3H2C3 type) 6 (RNF6), transcript variant 3, mRNA.	563					negative regulation of axon extension|positive regulation of transcription, DNA-dependent|protein K27-linked ubiquitination|protein K48-linked ubiquitination|protein K6-linked ubiquitination|regulation of androgen receptor signaling pathway|ubiquitin-dependent protein catabolic process	PML body|axon|cytoplasm	androgen receptor binding|ubiquitin-protein ligase activity|zinc ion binding			breast(2)|endometrium(2)|kidney(1)|large_intestine(9)|lung(3)|ovary(2)|prostate(2)|skin(2)	23	Colorectal(5;0.000442)	Lung SC(185;0.0156)|Breast(139;0.147)		all cancers(112;0.00893)|Epithelial(112;0.0481)|OV - Ovarian serous cystadenocarcinoma(117;0.148)|GBM - Glioblastoma multiforme(144;0.23)|Lung(94;0.245)		CTACTGTCACTGTTTCGAGTA	0.483000														118			44		0	0	0.045515	0	0
KRTAP4-6	81871	broad.mit.edu	37	17	39296167	39296167	+	Silent	SNP	A	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr17:39296167A>G	uc010cxk.2	-	0	573	c.573T>C	c.(571-573)atT>atC	p.I191I		NM_030976	NP_112238	Q9BYQ5	KRA46_HUMAN	Homo sapiens keratin associated protein 4-6 (KRTAP4-6), mRNA.	187						keratin filament				endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|lung(1)|prostate(1)|urinary_tract(1)	9						GGCAGGTGGAAATGACACAGG	0.627000														18			3		0	0	0.014758	0	0
CHD6	84181	broad.mit.edu	37	20	40080522	40080522	+	Missense_Mutation	SNP	C	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr20:40080522C>G	uc002xka.1	-	21	3645	c.3467G>C	c.(3466-3468)tGg>tCg	p.W1156S		NM_032221	NP_115597	Q8TD26	CHD6_HUMAN	Homo sapiens chromodomain helicase DNA binding protein 6 (CHD6), mRNA.	1156					chromatin remodeling|nervous system development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	ATP binding|ATP-dependent helicase activity|DNA binding|chromatin binding			breast(8)|central_nervous_system(2)|cervix(2)|endometrium(5)|kidney(4)|large_intestine(24)|lung(53)|ovary(8)|prostate(5)|skin(8)|stomach(1)|urinary_tract(9)	129		Myeloproliferative disorder(115;0.00425)				GATCAGTTCCCAAATGAAACT	0.522000														194			35		0	0	0.027894	0	0
AK093279	0	broad.mit.edu	37	13	21875674	21875674	+	RNA	SNP	C	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr13:21875674C>T	uc001unz.1	+	1		c.307C>T								Homo sapiens cDNA FLJ33446 fis, clone BRAMY1000095.																		GCTTGTGGACCGTGCGTGTTC	0.502000														25			3		0	0	0.004672	0	0
TMCO4	255104	broad.mit.edu	37	1	20067299	20067299	+	Missense_Mutation	SNP	T	C	C	rs147635887		TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr1:20067299T>C	uc001bcn.3	-	10	1255	c.1013A>G	c.(1012-1014)cAg>cGg	p.Q338R	TMCO4_uc001bco.1_Missense_Mutation_p.Q338R|TMCO4_uc001bcp.1_Missense_Mutation_p.Q298R	NM_181719	NP_859070	Q5TGY1	TMCO4_HUMAN	Homo sapiens transmembrane and coiled-coil domains 4 (TMCO4), mRNA.	338						integral to membrane				biliary_tract(1)|breast(2)|endometrium(2)|kidney(1)|lung(11)|skin(1)|upper_aerodigestive_tract(1)	19		Colorectal(325;0.000147)|Renal(390;0.000469)|all_lung(284;0.00519)|Breast(348;0.00526)|Lung NSC(340;0.00544)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0439)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00708)|COAD - Colon adenocarcinoma(152;2.28e-05)|BRCA - Breast invasive adenocarcinoma(304;5.8e-05)|Kidney(64;0.000367)|GBM - Glioblastoma multiforme(114;0.000377)|KIRC - Kidney renal clear cell carcinoma(64;0.00459)|STAD - Stomach adenocarcinoma(196;0.0072)|READ - Rectum adenocarcinoma(331;0.0862)|Lung(427;0.223)		TAGGGCCTCCTGGGCCACCAT	0.587000														77			4		0	0	0.009096	0	0
FCGRT	2217	broad.mit.edu	37	19	50017180	50017180	+	Missense_Mutation	SNP	T	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr19:50017180T>C	uc002pog.2	+	1	337	c.115T>C	c.(115-117)Tcg>Ccg	p.S39P	FCGRT_uc002poe.2_Missense_Mutation_p.S39P|FCGRT_uc002pof.2_5'UTR|FCGRT_uc010yax.2_Missense_Mutation_p.S39P|FCGRT_uc002poh.2_5'Flank	NM_004107	NP_004098	P55899	FCGRN_HUMAN	Homo sapiens Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2, mRNA.	39	Alpha-1.				antigen processing and presentation|female pregnancy|immune response	MHC class I protein complex|integral to membrane	IgG binding|receptor activity			endometrium(3)|kidney(2)|lung(1)|ovary(1)|prostate(1)|skin(1)	9		all_lung(116;7.84e-06)|Lung NSC(112;2.8e-05)|all_neural(266;0.0966)|Ovarian(192;0.231)		OV - Ovarian serous cystadenocarcinoma(262;0.00291)|GBM - Glioblastoma multiforme(134;0.0156)		CGCGGTGTCCTCGCCTGCCCC	0.657000														138			54		0	0	0.048971	0	0
RGS12	6002	broad.mit.edu	37	4	3441324	3441324	+	Silent	SNP	T	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr4:3441324T>C	uc003ggw.3	+	17	5161	c.4257T>C	c.(4255-4257)ccT>ccC	p.P1419P	RGS12_uc003ggz.3_Silent_p.P771P|RGS12_uc003gha.3_Silent_p.P761P|RGS12_uc010icv.3_Silent_p.P618P|HGFAC_uc003ghc.3_5'Flank|HGFAC_uc010icw.3_5'Flank	NM_198229	NP_937872	O14924	RGS12_HUMAN	Homo sapiens regulator of G-protein signaling 12 (RGS12), transcript variant 1, mRNA.	1419						condensed nuclear chromosome|cytoplasm|plasma membrane	GTPase activator activity|receptor signaling protein activity			autonomic_ganglia(1)|breast(4)|endometrium(3)|kidney(2)|large_intestine(9)|lung(16)|ovary(1)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	43				UCEC - Uterine corpus endometrioid carcinoma (64;0.168)		GTGGTGGGCCTCCTACATCAG	0.677000														30			7		0	0	0.029380	0	0
BHLHB9	80823	broad.mit.edu	37	X	102004858	102004858	+	Missense_Mutation	SNP	G	C	C			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chrX:102004858G>C	uc022cbi.1	+	0	935	c.935G>C	c.(934-936)tGt>tCt	p.C312S	BHLHB9_uc010nog.3_Missense_Mutation_p.C312S|BHLHB9_uc011mrq.2_Missense_Mutation_p.C312S|BHLHB9_uc011mrr.2_Missense_Mutation_p.C312S|BHLHB9_uc011mrs.2_Missense_Mutation_p.C312S|BHLHB9_uc011mrt.2_Missense_Mutation_p.C312S|BHLHB9_uc004ejo.3_Missense_Mutation_p.C312S|BHLHB9_uc011mru.2_Missense_Mutation_p.C312S|BHLHB9_uc011mrv.2_Missense_Mutation_p.C312S	NM_030639	NP_085142	Q6PI77	BHLH9_HUMAN	Homo sapiens basic helix-loop-helix domain containing, class B, 9 (BHLHB9), transcript variant 2, mRNA.	312						cytoplasm|nucleus	binding			cervix(1)|endometrium(6)|kidney(3)|large_intestine(1)|lung(8)|ovary(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	26						CCATTTGCTTGTCCTTGCAAA	0.398000														40			17		0	0	0.033300	0	0
DLEC1	9940	broad.mit.edu	37	3	38159473	38159473	+	Silent	SNP	A	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr3:38159473A>G	uc003chp.1	+	32	4683	c.4662A>G	c.(4660-4662)tcA>tcG	p.S1554S	DLEC1_uc003cho.1_Silent_p.S1554S|DLEC1_uc010hgv.1_Silent_p.S1557S|DLEC1_uc003chr.1_Silent_p.S625S|DLEC1_uc003chs.1_Silent_p.S111S	NM_007337	NP_031363	Q9Y238	DLEC1_HUMAN	Homo sapiens deleted in lung and esophageal cancer 1 (DLEC1), transcript variant DLEC1-S3, mRNA.	1554					negative regulation of cell proliferation	cytoplasm		p.A1553V(1)		NS(1)|breast(3)|central_nervous_system(3)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(9)|lung(14)|ovary(3)|pancreas(3)|prostate(1)|skin(5)|upper_aerodigestive_tract(2)	51				KIRC - Kidney renal clear cell carcinoma(284;0.0664)|Kidney(284;0.0827)		AGACAGCCTCAGCGGACAAGC	0.612000											OREG0015476	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		16			5		0	0	0.014758	0	0
CCDC75	253635	broad.mit.edu	37	2	37319336	37319336	+	Missense_Mutation	SNP	A	T	T			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:37319336A>T	uc010ezz.3	+	5	611	c.466A>T	c.(466-468)Atg>Ttg	p.M156L	CCDC75_uc002rpr.4_Missense_Mutation_p.M53L	NM_174931	NP_777591	Q8N954	CCD75_HUMAN	Homo sapiens coiled-coil domain containing 75 (CCDC75), mRNA.	156						intracellular	nucleic acid binding			endometrium(2)|kidney(3)|large_intestine(1)|urinary_tract(1)	7		all_hematologic(82;0.21)				GCAAGATGAAATGAAGCTAGA	0.358000														17			8		0	0	0.047766	0	0
RTKN	6242	broad.mit.edu	37	2	74657398	74657398	+	Missense_Mutation	SNP	A	G	G			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:74657398A>G	uc002sle.3	-	4	643	c.526T>C	c.(526-528)Ttt>Ctt	p.F176L	RTKN_uc002slc.3_Missense_Mutation_p.F163L|RTKN_uc002sld.3_Missense_Mutation_p.F126L	NM_001015055	NP_001015056	Q9BST9	RTKN_HUMAN	Homo sapiens rhotekin (RTKN), transcript variant 1, mRNA.	176					Rho protein signal transduction|apoptosis|regulation of anti-apoptosis	intracellular	GTP binding|GTP-Rho binding|GTPase inhibitor activity			endometrium(3)|large_intestine(5)|lung(5)|skin(2)|upper_aerodigestive_tract(1)	16						TTGCTCTGAAAGGAGATGTCT	0.562000														32			7		0	0	0.038147	0	0
TRHR	7201	broad.mit.edu	37	8	110131438	110131438	+	Silent	SNP	G	A	A			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr8:110131438G>A	uc003ymz.4	+	1	1040	c.951G>A	c.(949-951)ccG>ccA	p.P317P		NM_003301	NP_003292	P34981	TRFR_HUMAN	Homo sapiens thyrotropin-releasing hormone receptor (TRHR), mRNA.	317						integral to plasma membrane	thyrotropin-releasing hormone receptor activity	p.P317L(1)		endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(8)|lung(12)|prostate(4)|skin(4)|urinary_tract(1)	37			OV - Ovarian serous cystadenocarcinoma(57;2.3e-11)			CCATCAACCCGGTGATTTACA	0.438000														231			58		0	0	0.048971	0	0
APOB	338	broad.mit.edu	37	2	21266775	21266783	+	In_Frame_Del	DEL	GCAGCGCCA	-	-	rs17240441		TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr2:21266775_21266783delGCAGCGCCA	uc002red.3	-	0	163_171	c.35_43delTGGCGCTGC	c.(34-45)ctggcgctgcct>cct	p.LAL12del		NM_000384	NP_000375	P04114	APOB_HUMAN	Homo sapiens apolipoprotein B (including Ag(x) antigen) (APOB), mRNA.	12				Missing (in Ref. 5; AAB60718/CAA28420).	cholesterol homeostasis|cholesterol metabolic process|leukocyte migration|low-density lipoprotein particle clearance|low-density lipoprotein particle remodeling|platelet activation|positive regulation of cholesterol storage|positive regulation of macrophage derived foam cell differentiation|receptor-mediated endocytosis|response to virus	chylomicron remnant|clathrin-coated endocytic vesicle membrane|endoplasmic reticulum lumen|endoplasmic reticulum membrane|endosome lumen|endosome membrane|intermediate-density lipoprotein particle|low-density lipoprotein particle|mature chylomicron|microsome|plasma membrane|very-low-density lipoprotein particle	cholesterol transporter activity|enzyme binding|heparin binding|low-density lipoprotein particle receptor binding|phospholipid binding|protein heterodimerization activity			NS(5)|autonomic_ganglia(1)|breast(6)|central_nervous_system(4)|cervix(3)|endometrium(19)|kidney(10)|large_intestine(63)|liver(5)|lung(125)|ovary(16)|pancreas(1)|prostate(5)|skin(31)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(6)	305	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)				Atorvastatin(DB01076)	agcagcgcaggcagcgccagcagcgccag	0.794													---	5	---	---	3	---					
FKBP9	11328	broad.mit.edu	37	7	33014881	33014881	+	Frame_Shift_Del	DEL	C	-	-			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr7:33014881delC	uc011kal.2	+	3	795	c.614delC	c.(613-615)accfs	p.T205fs	AVL9_uc011kai.2_Intron|FKBP9_uc011kak.1_Non-coding_Transcript|FKBP9_uc003tdh.3_Frame_Shift_Del_p.T152fs|FKBP9_uc010kwm.3_Frame_Shift_Del_p.T59fs	NM_007270	NP_009201	O95302	FKBP9_HUMAN	Homo sapiens FK506 binding protein 9, 63 kDa (FKBP9), mRNA.	152	PPIase FKBP-type 2.				protein folding	endoplasmic reticulum|membrane	FK506 binding|calcium ion binding|peptidyl-prolyl cis-trans isomerase activity			central_nervous_system(13)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(6)|lung(9)|ovary(2)|upper_aerodigestive_tract(1)	39			GBM - Glioblastoma multiforme(11;0.0156)			CAGATTCACACCTATTTCAAG	0.468													---	78	---	---	17	---					
SLC17A6	57084	broad.mit.edu	37	11	22363111	22363112	+	Frame_Shift_Del	DEL	GA	-	-			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr11:22363111_22363112delGA	uc001mqk.3	+	1	537_538	c.124_125delGA	c.(124-126)gagfs	p.E42fs		NM_020346	NP_065079	Q9P2U8	VGLU2_HUMAN	Homo sapiens solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 (SLC17A6), mRNA.	42					sodium ion transport	cell junction|integral to membrane|synaptic vesicle membrane|synaptosome	L-glutamate transmembrane transporter activity|symporter activity			breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(3)|lung(28)|ovary(3)|skin(4)|upper_aerodigestive_tract(3)	50						GGAGACAATCGAGCTGACGGAG	0.649													---	95	---	---	17	---					
MORN3	283385	broad.mit.edu	37	12	122107353	122107353	+	Frame_Shift_Del	DEL	G	-	-			TCGA-A4-7286-01A-11D-2136-08	TCGA-A4-7286-10A-01D-2136-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4ab0f9d3-99a7-4bcc-9b8e-643a30a9979c	08ec176f-4bd6-4128-97b3-ea6aa610eeb9	g.chr12:122107353delG	uc001uax.3	-	0	208	c.37delC	c.(37-39)ctgfs	p.L13fs	MORN3_uc001uay.3_Non-coding_Transcript	NM_173855	NP_776254	Q6PF18	MORN3_HUMAN	Homo sapiens MORN repeat containing 3 (MORN3), mRNA.	13										breast(2)|large_intestine(1)|lung(4)|skin(1)|stomach(1)	9	all_neural(191;0.0684)|Medulloblastoma(191;0.0922)			OV - Ovarian serous cystadenocarcinoma(86;0.000409)|Epithelial(86;0.00145)		CCCTTCCACAGGGACTCCGAC	0.602													---	194	---	---	42	---					
