Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
DAPP1	27071	broad.mit.edu	37	4	100787246	100787246	+	Missense_Mutation	SNP	G	C	C			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr4:100787246G>C	uc003hvf.4	+	7	832	c.742G>C	c.(742-744)Gat>Cat	p.D248H	DAPP1_uc010ilh.3_Missense_Mutation_p.D248H	NM_014395	NP_055210	Q9UN19	DAPP1_HUMAN	Homo sapiens dual adaptor of phosphotyrosine and 3-phosphoinositides (DAPP1), mRNA.	248	PH.				signal transduction	cytoplasm|plasma membrane	phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-3,4-bisphosphate binding|protein tyrosine phosphatase activity			endometrium(1)|kidney(1)|lung(4)	6				OV - Ovarian serous cystadenocarcinoma(123;7.04e-09)		AGTAGAAGCTGATGAGTGGAT	0.343000														34			11		0	0	0.00010058	0	0
A2ML1	144568	broad.mit.edu	37	12	9000291	9000291	+	Silent	SNP	C	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr12:9000291C>T	uc001quz.4	+	14	1928	c.1830C>T	c.(1828-1830)cgC>cgT	p.R610R	A2ML1_uc001qva.1_Silent_p.R190R|A2ML1_uc010sgm.2_Silent_p.R110R	NM_144670	NP_653271	B3KVV6	B3KVV6_HUMAN	Homo sapiens alpha-2-macroglobulin-like 1 (A2ML1), mRNA.	454						extracellular space	endopeptidase inhibitor activity			NS(2)|breast(5)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|liver(2)|lung(36)|ovary(2)|skin(4)|stomach(1)|urinary_tract(1)	80						TGAGCAACCGCTCTGTGAGTA	0.557000														141			11		0	0	6.40141e-05	0	0
CMTM1	113540	broad.mit.edu	37	16	66612903	66612903	+	Silent	SNP	G	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr16:66612903G>A	uc002epr.4	+	3	927	c.860G>A	c.(859-861)tGa>tAa	p.*287*	CMTM1_uc021tjs.1_3'UTR|CMTM1_uc021tjt.1_Silent_p.*169*|CMTM1_uc021tju.1_Silent_p.*116*|CMTM1_uc002eph.4_3'UTR|CMTM1_uc002epi.4_Silent_p.*170*|CMTM1_uc002epl.4_Silent_p.*123*|CMTM1_uc002epj.4_3'UTR|CMTM1_uc002epk.4_Silent_p.*117*|CMTM1_uc002epa.4_3'UTR|CMTM1_uc002epb.4_Non-coding_Transcript|CMTM1_uc002epc.4_Non-coding_Transcript|CMTM1_uc002epd.4_Non-coding_Transcript|CMTM1_uc002epe.4_Non-coding_Transcript|CMTM1_uc002epf.4_Non-coding_Transcript|CMTM1_uc002epg.4_Non-coding_Transcript|CMTM1_uc002epm.4_Non-coding_Transcript|CMTM1_uc002epo.4_Non-coding_Transcript|CMTM1_uc002epp.4_Non-coding_Transcript|CMTM1_uc002epq.4_Non-coding_Transcript|CMTM1_uc010cds.3_Non-coding_Transcript|CMTM1_uc002epn.4_3'UTR|CMTM1_uc002eps.3_Non-coding_Transcript|CMTM2_uc002ept.3_5'Flank|CMTM2_uc010cdu.3_5'Flank	NM_052999	NP_443725	Q8IZ96	CKLF1_HUMAN	Homo sapiens CKLF-like MARVEL transmembrane domain containing 1 (CMTM1), transcript variant 17, mRNA.	0					chemotaxis	extracellular space|integral to membrane	cytokine activity			breast(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(2)	7		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.0702)|Epithelial(162;0.222)		AGGCCCGCCTGAAGCCAGCCC	0.627000														50			34		0	0	0.000409698	0	0
GLUL	2752	broad.mit.edu	37	1	182356292	182356292	+	Missense_Mutation	SNP	A	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr1:182356292A>T	uc001gpa.2	-	2	545	c.302T>A	c.(301-303)gTt>gAt	p.V101D	GLUL_uc010pnt.2_5'Flank|GLUL_uc001gpb.2_Missense_Mutation_p.V101D|GLUL_uc001gpc.2_Missense_Mutation_p.V101D|GLUL_uc001gpd.2_Missense_Mutation_p.V101D	NM_001033056	NP_002056	P15104	GLNA_HUMAN	Homo sapiens glutamate-ammonia ligase (GLUL), transcript variant 3, mRNA.	101					cell proliferation|glutamine biosynthetic process|neurotransmitter uptake	Golgi apparatus|cytosol|mitochondrion	ATP binding|glutamate decarboxylase activity|glutamate-ammonia ligase activity|identical protein binding			endometrium(2)|large_intestine(5)|lung(8)|upper_aerodigestive_tract(1)	16					Asparaginase(DB00023)|L-Glutamic Acid(DB00142)|L-Glutamine(DB00130)|L-Methionine(DB00134)	GTACTTGAAAACTTCACATAA	0.493000														78			9		0	0	2.17888e-05	0	0
SYNE1	23345	broad.mit.edu	37	6	152546984	152546984	+	Nonsense_Mutation	SNP	C	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr6:152546984C>A	uc021zhb.1	-	113	21446	c.21223G>T	c.(21223-21225)Gaa>Taa	p.E7075*	SYNE1_uc003qos.4_Nonsense_Mutation_p.E1599*|SYNE1_uc003qot.4_Nonsense_Mutation_p.E7004*|SYNE1_uc003qou.4_Nonsense_Mutation_p.E7075*|SYNE1_uc003qor.4_5'UTR	NM_182961	NP_892006	Q8NF91	SYNE1_HUMAN	Homo sapiens spectrin repeat containing, nuclear envelope 1 (SYNE1), transcript variant 1, mRNA.	7075				E -> D (in Ref. 1; AAL33798, 2; AAN60442 and 4; AAO27774).	Golgi organization|cell death|cytoskeletal anchoring at nuclear membrane|muscle cell differentiation|nuclear matrix anchoring at nuclear membrane	Golgi apparatus|SUN-KASH complex|cytoskeleton|integral to membrane|nuclear outer membrane|postsynaptic membrane|sarcomere	actin binding|lamin binding			NS(3)|biliary_tract(1)|breast(17)|central_nervous_system(21)|cervix(3)|endometrium(27)|haematopoietic_and_lymphoid_tissue(4)|kidney(16)|large_intestine(138)|liver(1)|lung(190)|ovary(11)|pancreas(5)|prostate(12)|skin(20)|stomach(3)|upper_aerodigestive_tract(33)|urinary_tract(19)	524		Ovarian(120;0.0955)	BRCA - Breast invasive adenocarcinoma(37;0.243)	OV - Ovarian serous cystadenocarcinoma(155;2.24e-10)		ACTTCTTTTTCTTTTGCTTTA	0.378000										HNSCC(10;0.0054)				90			12		1.5842e-08	1.14912e-06	0.000151284	1	0
FLJ43315	644316	broad.mit.edu	37	GL000211.1	107007	107007	+	RNA	SNP	G	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chrGL000211.1:107007G>A	uc003boa.3	+	3		c.706G>A								Homo sapiens asparagine synthetase pseudogene (FLJ43315), non-coding RNA.																		CTCCTGGTTAGCAGAAAATGC	0.408000														386			10		0	0	3.86212e-05	0	0
FAM47B	170062	broad.mit.edu	37	X	34961454	34961454	+	Missense_Mutation	SNP	G	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chrX:34961454G>A	uc004ddi.2	+	0	542	c.506G>A	c.(505-507)cGg>cAg	p.R169Q		NM_152631	NP_689844	Q8NA70	FA47B_HUMAN	Homo sapiens family with sequence similarity 47, member B (FAM47B), mRNA.	169										breast(3)|central_nervous_system(3)|endometrium(8)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(13)|lung(28)|ovary(4)|prostate(3)|skin(2)|upper_aerodigestive_tract(3)	71						TGTGAGGCCCGGGAGAAGACA	0.592000														5			28		0	0	0.000147802	0	0
ADAM30	11085	broad.mit.edu	37	1	120436921	120436921	+	Missense_Mutation	SNP	C	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr1:120436921C>T	uc001eij.3	-	0	2227	c.2039G>A	c.(2038-2040)gGg>gAg	p.G680E		NM_021794	NP_068566	Q9UKF2	ADA30_HUMAN	Homo sapiens ADAM metallopeptidase domain 30 (ADAM30), mRNA.	680					proteolysis	integral to membrane	metalloendopeptidase activity|zinc ion binding			NS(1)|autonomic_ganglia(1)|breast(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(11)|lung(16)|ovary(2)|skin(2)	38	all_cancers(5;7.07e-10)|all_epithelial(5;1.62e-10)|all_neural(166;0.153)|Breast(55;0.234)	all_lung(203;1.55e-06)|Lung NSC(69;1.04e-05)|all_epithelial(167;0.00138)		Lung(183;0.0204)|LUSC - Lung squamous cell carcinoma(189;0.117)		GGGAATCGCCCCTCTGAGCAG	0.473000														52			27		0	0	9.22233e-05	0	0
ARSK	153642	broad.mit.edu	37	5	94922371	94922371	+	Missense_Mutation	SNP	A	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr5:94922371A>G	uc003kld.3	+	4	963	c.805A>G	c.(805-807)Aaa>Gaa	p.K269E	ARSK_uc010jbg.3_Missense_Mutation_p.K110E|ARSK_uc011cum.2_Non-coding_Transcript	NM_198150	NP_937793	Q6UWY0	ARSK_HUMAN	Homo sapiens arylsulfatase family, member K (ARSK), mRNA.	269						extracellular region	arylsulfatase activity|metal ion binding			endometrium(2)|kidney(1)|large_intestine(3)|lung(8)|pancreas(1)|skin(1)	16		all_cancers(142;3.38e-06)|all_epithelial(76;6.57e-09)|all_lung(232;0.00307)|Lung NSC(167;0.00452)|Ovarian(225;0.00473)		all cancers(79;6.5e-16)		AAGATTTACAAAAAAAGAAAT	0.338000														58			18		0	0	7.07596e-05	0	0
KRTAP10-10	353333	broad.mit.edu	37	21	46057373	46057373	+	Silent	SNP	C	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr21:46057373C>T	uc002zfq.3	+	0	101	c.39C>T	c.(37-39)tgC>tgT	p.C13C	TSPEAR_uc002zfe.1_Intron|TSPEAR_uc010gpv.1_Intron	NM_181688	NP_859016	P60014	KR10A_HUMAN	Homo sapiens keratin associated protein 10-10 (KRTAP10-10), mRNA.	13						keratin filament		p.C13C(2)		NS(1)|endometrium(2)|kidney(1)|lung(6)|prostate(1)|skin(2)	13						CCAGCGCCTGCACTGACTCTT	0.652000														115			31		0	0	0.000409698	0	0
PTPN13	5783	broad.mit.edu	37	4	87691259	87691259	+	Silent	SNP	C	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr4:87691259C>T	uc003hpz.3	+	29	5190	c.4710C>T	c.(4708-4710)gtC>gtT	p.V1570V	PTPN13_uc003hpy.3_Silent_p.V1575V|PTPN13_uc003hqa.3_Silent_p.V1551V|PTPN13_uc003hqb.3_Silent_p.V1379V|PTPN13_uc003hqc.1_5'UTR	NM_080683	NP_542414	Q12923	PTN13_HUMAN	Homo sapiens protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (PTPN13), transcript variant 1, mRNA.	1570	PDZ 3.					cytoplasm|cytoskeleton|plasma membrane	protein binding|protein tyrosine phosphatase activity			NS(4)|breast(3)|central_nervous_system(1)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(12)|large_intestine(23)|lung(24)|ovary(4)|prostate(3)|skin(7)|upper_aerodigestive_tract(1)|urinary_tract(2)	93		Hepatocellular(203;0.114)|all_hematologic(202;0.21)|Acute lymphoblastic leukemia(40;0.242)		OV - Ovarian serous cystadenocarcinoma(123;0.00082)		CCCAGGAAGTCATATCTGCTC	0.443000														23			9		0	0	0.000274275	0	0
TTLL6	284076	broad.mit.edu	37	17	46862380	46862380	+	Missense_Mutation	SNP	T	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr17:46862380T>G	uc021tzm.1	-	12	1980	c.1945A>C	c.(1945-1947)Aat>Cat	p.N649H	TTLL6_uc002iob.3_Missense_Mutation_p.N342H|TTLL6_uc010dbi.3_Non-coding_Transcript|TTLL6_uc002ioc.3_Missense_Mutation_p.N402H|TTLL6_uc002iod.3_Missense_Mutation_p.N496H	NM_001130918	NP_001124390	Q8N841	TTLL6_HUMAN	Homo sapiens tubulin tyrosine ligase-like family, member 6 (TTLL6), transcript variant 1, mRNA.	601						cilium|microtubule basal body	ATP binding|tubulin binding|tubulin-tyrosine ligase activity			endometrium(1)|large_intestine(5)|lung(9)|prostate(1)|skin(2)	18						CTGCTGAGATTGATATTCCTC	0.547000														111			80		0	0	0.000147903	0	0
TEX15	56154	broad.mit.edu	37	8	30694449	30694449	+	Silent	SNP	T	C	C			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr8:30694449T>C	uc003xil.3	-	2	8202	c.8202A>G	c.(8200-8202)caA>caG	p.Q2734Q		NM_031271	NP_112561	Q9BXT5	TEX15_HUMAN	Homo sapiens testis expressed 15 (TEX15), mRNA.	2734										NS(2)|breast(3)|cervix(5)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(38)|lung(56)|ovary(5)|pancreas(1)|prostate(2)|skin(7)|upper_aerodigestive_tract(5)|urinary_tract(1)	138				KIRC - Kidney renal clear cell carcinoma(542;0.0918)|Kidney(114;0.111)		GTATTTGAGATTGAAAATACC	0.408000														50			31		0	0	7.24521e-05	0	0
MTIF2	4528	broad.mit.edu	37	2	55473595	55473595	+	Silent	SNP	G	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr2:55473595G>A	uc002ryn.3	-	10	1721	c.984C>T	c.(982-984)ggC>ggT	p.G328G	MTIF2_uc010yox.2_5'UTR|MTIF2_uc002ryo.3_Silent_p.G328G	NM_001005369	NP_002444	P46199	IF2M_HUMAN	Homo sapiens mitochondrial translational initiation factor 2 (MTIF2), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.	328	G-domain.				regulation of translational initiation	mitochondrion	GTP binding|GTPase activity|ribosomal small subunit binding|translation initiation factor activity			breast(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(5)|ovary(1)|prostate(1)|skin(1)|stomach(2)|upper_aerodigestive_tract(2)	24						TCAGATTATCGCCCTTTAACA	0.353000														66			9		0	0	2.17888e-05	0	0
MUC2	4583	broad.mit.edu	37	11	1099777	1099777	+	Silent	SNP	T	C	C			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr11:1099777T>C	uc001lsx.1	+	41	7389	c.7362T>C	c.(7360-7362)ccT>ccC	p.P2454P		NM_002457	NP_002448	Q02817	MUC2_HUMAN	Homo sapiens mucin 2, oligomeric mucus/gel-forming (MUC2), mRNA.	4820						inner mucus layer|outer mucus layer	protein binding			NS(3)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(26)|haematopoietic_and_lymphoid_tissue(4)|kidney(11)|large_intestine(5)|lung(22)|ovary(2)|prostate(16)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)	102		all_cancers(49;1.08e-07)|all_epithelial(84;5.08e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.191)		BRCA - Breast invasive adenocarcinoma(625;0.000207)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)	Pranlukast(DB01411)	GTGTGGGACCTGACAATGTGC	0.572000														67			41		0	0	0.000125731	0	0
AIM2	9447	broad.mit.edu	37	1	159033450	159033450	+	Missense_Mutation	SNP	C	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr1:159033450C>G	uc001ftj.1	-	4	1076	c.831G>C	c.(829-831)aaG>aaC	p.K277N		NM_004833	NP_004824	O14862	AIM2_HUMAN	Homo sapiens absent in melanoma 2 (AIM2), mRNA.	277	HIN-200.				cellular response to drug|immune response|interleukin-1 beta secretion	mitochondrion|nucleus				breast(1)|large_intestine(1)|lung(7)|ovary(2)|pancreas(2)|prostate(2)|skin(1)	16	all_hematologic(112;0.0429)					ATATGTTTTTCTTCTTTTCTG	0.398000														123			55		0	0	0.000147903	0	0
MAGEL2	54551	broad.mit.edu	37	15	23890238	23890238	+	Missense_Mutation	SNP	C	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr15:23890238C>G	uc001ywj.4	-	0	2756	c.2652G>C	c.(2650-2652)aaG>aaC	p.K884N		NM_019066	NP_061939			Homo sapiens MAGE-like 2 (MAGEL2), mRNA.											breast(1)|endometrium(1)|large_intestine(2)|lung(2)|upper_aerodigestive_tract(1)	7		all_cancers(20;1.78e-24)|all_epithelial(15;7.75e-22)|Lung NSC(15;2.96e-18)|all_lung(15;2.8e-17)|Breast(32;0.000625)|Colorectal(260;0.14)		all cancers(64;1.84e-06)|Epithelial(43;1.2e-05)|BRCA - Breast invasive adenocarcinoma(123;0.00177)		TCCGGGTGGCCTTGCCGGAGC	0.637000														76			10		0	0	3.86212e-05	0	0
ABCA12	26154	broad.mit.edu	37	2	215865517	215865517	+	Missense_Mutation	SNP	C	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr2:215865517C>G	uc002vew.3	-	21	3311	c.3091G>C	c.(3091-3093)Gca>Cca	p.A1031P	ABCA12_uc002vev.3_Missense_Mutation_p.A713P|ABCA12_uc010zjn.2_5'UTR	NM_173076	NP_775099	Q86UK0	ABCAC_HUMAN	Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 12 (ABCA12), transcript variant 1, mRNA.	1031					cellular homeostasis|lipid transport	integral to membrane	ATP binding|ATPase activity			NS(3)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(45)|lung(44)|ovary(8)|pancreas(2)|prostate(4)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	139		Renal(323;0.127)		Epithelial(149;1.01e-05)|all cancers(144;0.00112)|LUSC - Lung squamous cell carcinoma(224;0.00829)|Lung(261;0.011)		TCAATGATTGCTCTTTCAATA	0.428000														131			71		0	0	0.000147903	0	0
TMEM5	10329	broad.mit.edu	37	12	64174892	64174892	+	Nonsense_Mutation	SNP	T	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr12:64174892T>G	uc001srq.1	+	1	367	c.263T>G	c.(262-264)tTa>tGa	p.L88*	TMEM5_uc001srs.1_5'UTR	NM_014254	NP_055069	Q9Y2B1	TMEM5_HUMAN	Homo sapiens transmembrane protein 5 (TMEM5), mRNA.	88						integral to plasma membrane				breast(1)|large_intestine(3)|liver(2)|lung(7)|prostate(1)|skin(1)	15		Myeloproliferative disorder(1001;0.0255)	BRCA - Breast invasive adenocarcinoma(9;0.0985)	GBM - Glioblastoma multiforme(28;9e-08)|BRCA - Breast invasive adenocarcinoma(357;0.000175)		CTTCAAATATTAGATAAATCC	0.363000														132			75		0	0	0.000147903	0	0
STEAP4	79689	broad.mit.edu	37	7	87910314	87910314	+	Silent	SNP	C	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr7:87910314C>A	uc022agz.1	-	4	1288	c.1065G>T	c.(1063-1065)ggG>ggT	p.G355G	STEAP4_uc003ujs.3_Silent_p.G355G|STEAP4_uc010lek.3_Silent_p.G179G	NM_001205315	NP_001192244	Q687X5	STEA4_HUMAN	Homo sapiens STEAP family member 4 (STEAP4), transcript variant 2, mRNA.	355	Ferric oxidoreductase.				fat cell differentiation|ion transport|iron ion homeostasis	Golgi membrane|integral to membrane|plasma membrane	electron carrier activity|flavin adenine dinucleotide binding|iron ion binding|oxidoreductase activity			breast(2)|central_nervous_system(1)|endometrium(1)|large_intestine(3)|lung(5)|upper_aerodigestive_tract(3)	15	Esophageal squamous(14;0.00802)					ACAGAAAAAACCCAAGTATTC	0.408000														66			16		2.32078e-09	1.7255e-07	0.000308642	1	0
ZNF295	49854	broad.mit.edu	37	21	43413770	43413770	+	Silent	SNP	T	C	C			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr21:43413770T>C	uc021wjo.1	-	0	435	c.435A>G	c.(433-435)caA>caG	p.Q145Q	ZNF295_uc002yzz.4_Silent_p.Q145Q|ZNF295_uc002zab.4_Silent_p.Q145Q|ZNF295_uc002yzy.4_Silent_p.Q145Q|ZNF295_uc002zaa.4_Silent_p.Q145Q|ZNF295_uc010gov.1_Silent_p.Q145Q|ZNF295_uc002zac.2_Silent_p.Q145Q	NM_020727	NP_065778	Q9ULJ3	ZN295_HUMAN	Homo sapiens zinc finger protein 295 (ZNF295), transcript variant 2, mRNA.	145					negative regulation of transcription, DNA-dependent|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	methyl-CpG binding|protein binding|zinc ion binding	p.Q145L(1)		breast(1)|central_nervous_system(3)|endometrium(4)|kidney(1)|large_intestine(7)|lung(10)|ovary(3)|prostate(1)|skin(2)|soft_tissue(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	37						CACTTCTCTTTTGAGAACTGT	0.403000														68			50		0	0	0.000147903	0	0
LOC100133050	100133050	broad.mit.edu	37	5	99715528	99715528	+	RNA	SNP	C	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr5:99715528C>T	uc011cuw.1	-	3		c.382G>A								Homo sapiens glucuronidase, beta pseudogene (LOC100133050), non-coding RNA.																		AGCGGACAGTCGAAGCCCTTC	0.607000														16			4		0	0	1.23904e-05	0	0
EPX	8288	broad.mit.edu	37	17	56274480	56274480	+	Missense_Mutation	SNP	C	T	T	rs143329228		TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr17:56274480C>T	uc002ivq.3	+	6	1101	c.982C>T	c.(982-984)Cgg>Tgg	p.R328W		NM_000502	NP_000493	P11678	PERE_HUMAN	Homo sapiens eosinophil peroxidase (EPX), mRNA.	328					hydrogen peroxide catabolic process		heme binding|peroxidase activity|protein binding	p.R328R(1)		breast(2)|endometrium(9)|kidney(1)|large_intestine(9)|liver(2)|lung(20)|ovary(2)|prostate(2)|upper_aerodigestive_tract(1)	48						GCTCCGCAACCGGACCAACTA	0.617000														177			9		0	0	3.86212e-05	0	0
PCDH8	5100	broad.mit.edu	37	13	53422307	53422307	+	Missense_Mutation	SNP	C	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr13:53422307C>T	uc001vhi.3	-	0	469	c.265G>A	c.(265-267)Ggc>Agc	p.G89S	PCDH8_uc001vhj.3_Missense_Mutation_p.G89S	NM_002590	NP_002581	O95206	PCDH8_HUMAN	Homo sapiens protocadherin 8 (PCDH8), transcript variant 1, mRNA.	89	Cadherin 1.				cell-cell signaling|homophilic cell adhesion	cell junction|dendrite|integral to plasma membrane|postsynaptic membrane|presynaptic membrane	calcium ion binding			breast(1)|central_nervous_system(2)|endometrium(2)|large_intestine(5)|lung(23)|ovary(1)|skin(1)|urinary_tract(1)	36		Lung NSC(96;0.0019)|Breast(56;0.00235)|Hepatocellular(98;0.065)|Prostate(109;0.0771)|all_neural(104;0.173)		GBM - Glioblastoma multiforme(99;2.19e-08)		CGGTCCAGGCCGGCGTCCCCG	0.657000														50			30		0	0	0.000339439	0	0
PPP1R12A	4659	broad.mit.edu	37	12	80203769	80203769	+	Missense_Mutation	SNP	T	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr12:80203769T>G	uc001syz.3	-	9	1528	c.1261A>C	c.(1261-1263)Att>Ctt	p.I421L	PPP1R12A_uc010suc.2_Missense_Mutation_p.I334L|PPP1R12A_uc001sza.3_Missense_Mutation_p.I421L|PPP1R12A_uc010sud.2_Missense_Mutation_p.I421L|PPP1R12A_uc001szb.3_Missense_Mutation_p.I421L|PPP1R12A_uc001szc.2_Missense_Mutation_p.I421L	NM_002480	NP_001137358	O14974	MYPT1_HUMAN	Homo sapiens protein phosphatase 1, regulatory subunit 12A (PPP1R12A), transcript variant 1, mRNA.	421						contractile fiber	protein binding|signal transducer activity			breast(5)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(4)|large_intestine(7)|liver(1)|lung(4)|ovary(2)|skin(1)	29						TTGGGAGAAATTTTTGTAGCT	0.363000														38			16		0	0	9.7654e-05	0	0
ZFAT	57623	broad.mit.edu	37	8	135524765	135524765	+	Missense_Mutation	SNP	T	C	C			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr8:135524765T>C	uc003yup.3	-	13	3500	c.3314A>G	c.(3313-3315)cAg>cGg	p.Q1105R	ZFAT_uc011ljj.2_Missense_Mutation_p.Q224R|ZFAT_uc003yun.3_Missense_Mutation_p.Q1093R|ZFAT_uc003yuo.3_Missense_Mutation_p.Q1093R|ZFAT_uc010meh.3_Intron|ZFAT_uc010mej.3_Missense_Mutation_p.Q1043R|ZFAT_uc010mei.3_Non-coding_Transcript|ZFAT_uc003yuq.3_Missense_Mutation_p.Q1093R	NM_020863	NP_001161055	Q9P243	ZFAT_HUMAN	Homo sapiens zinc finger and AT hook domain containing (ZFAT), transcript variant 1, mRNA.	1105					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|nucleus	DNA binding|zinc ion binding			autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|endometrium(10)|kidney(9)|large_intestine(8)|lung(16)|prostate(3)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	54	all_epithelial(106;8.26e-19)|Lung NSC(106;3.47e-07)|all_lung(105;1.39e-06)|Ovarian(258;0.0102)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0432)			CACCGCTGCCTGTGTCCCTTG	0.532000														271			5		0	0	3.59834e-05	0	0
ZDBF2	57683	broad.mit.edu	37	2	207171574	207171574	+	Silent	SNP	G	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr2:207171574G>A	uc002vbp.2	+	4	2572	c.2322G>A	c.(2320-2322)cgG>cgA	p.R774R		NM_020923	NP_065974	Q9HCK1	ZDBF2_HUMAN	Homo sapiens zinc finger, DBF-type containing 2 (ZDBF2), mRNA.	774							nucleic acid binding|zinc ion binding			endometrium(4)|kidney(5)|large_intestine(28)|lung(50)|ovary(4)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	95						GAAAAGAACGGCACATTGACC	0.428000														259			49		0	0	0.000147903	0	0
GART	2618	broad.mit.edu	37	21	34877874	34877874	+	Missense_Mutation	SNP	A	C	C			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr21:34877874A>C	uc002yrz.3	-	19	3030	c.2719T>G	c.(2719-2721)Tgg>Ggg	p.W907G	GART_uc002yrx.3_Missense_Mutation_p.W907G|GART_uc010gmd.3_Missense_Mutation_p.W569G|GART_uc002yry.3_Missense_Mutation_p.W907G	NM_001136005	NP_001129478	P22102	PUR2_HUMAN	Homo sapiens phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (GART), transcript variant 3, mRNA.	907	GART.				'de novo' IMP biosynthetic process|purine base biosynthetic process	cytosol	ATP binding|metal ion binding|methyltransferase activity|phosphoribosylamine-glycine ligase activity|phosphoribosylformylglycinamidine cyclo-ligase activity|phosphoribosylglycinamide formyltransferase activity|protein binding			NS(2)|breast(1)|endometrium(3)|large_intestine(3)|lung(13)|ovary(3)|prostate(5)|urinary_tract(1)	31					Pemetrexed(DB00642)	TTACCATTCCACTTTTGGACA	0.398000														76			4		0	0	0.00024832	0	0
MGRN1	23295	broad.mit.edu	37	16	4700468	4700468	+	Missense_Mutation	SNP	G	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr16:4700468G>T	uc002cxa.3	+	1	328	c.191G>T	c.(190-192)gGc>gTc	p.G64V	MGRN1_uc002cwz.3_Missense_Mutation_p.G64V|MGRN1_uc010uxo.2_Missense_Mutation_p.G64V|MGRN1_uc010uxp.2_Missense_Mutation_p.G64V|MGRN1_uc010btw.3_Missense_Mutation_p.G64V|MGRN1_uc010uxq.2_Non-coding_Transcript	NM_015246	NP_056061	O60291	MGRN1_HUMAN	Homo sapiens mahogunin, ring finger 1 (MGRN1), transcript variant 1, mRNA.	64					endosome to lysosome transport|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of cAMP-mediated signaling|protein monoubiquitination	cytosol|early endosome|nucleus|plasma membrane	protein binding|ubiquitin-protein ligase activity|zinc ion binding			endometrium(3)|kidney(1)|large_intestine(2)|lung(4)|ovary(3)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(2)	18						AACTTCCTGGGCAGCCGCCCG	0.597000														74			34		4.14481e-20	3.16068e-18	0.000228196	1	0
FLJ36000	284124	broad.mit.edu	37	17	21904069	21904069	+	RNA	SNP	C	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr17:21904069C>G	uc002gza.2	+	0		c.8C>G								Homo sapiens uncharacterized FLJ36000 (FLJ36000), non-coding RNA.																		tccgaggctccggcctgacct	0.662000														8			4		0	0	0.00024832	0	0
GALNT7	51809	broad.mit.edu	37	4	174225146	174225146	+	Splice_Site	SNP	G	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr4:174225146G>A	uc003isz.4	+	8	1350	c.1267_splice	c.e8-1	p.I423_splice	GALNT7_uc011ckb.2_Splice_Site_p.I200_splice	NM_017423	NP_059119	Q86SF2	GALT7_HUMAN	Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) (GALNT7), mRNA.	423	Catalytic subdomain B.				protein O-linked glycosylation	Golgi membrane|integral to membrane	polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			central_nervous_system(1)|kidney(3)|large_intestine(5)|liver(1)|lung(9)	19		Prostate(90;0.0132)|Renal(120;0.0183)|Melanoma(52;0.0749)|all_hematologic(60;0.107)|all_neural(102;0.122)		all cancers(43;1.87e-18)|Epithelial(43;3.44e-17)|OV - Ovarian serous cystadenocarcinoma(60;2.48e-09)|STAD - Stomach adenocarcinoma(60;0.0019)|GBM - Glioblastoma multiforme(59;0.0119)|LUSC - Lung squamous cell carcinoma(193;0.0199)		TTCCTTCATAGATATGGCAGT	0.343000														94			45		0	0	0.000147903	0	0
ZCCHC17	51538	broad.mit.edu	37	1	31836979	31836979	+	Missense_Mutation	SNP	A	C	C	rs111803813		TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr1:31836979A>C	uc001bsp.1	+	7	801	c.665A>C	c.(664-666)gAc>gCc	p.D222A	ZCCHC17_uc001bsq.1_Missense_Mutation_p.D214A|ZCCHC17_uc010ogf.1_Missense_Mutation_p.D224A|ZCCHC17_uc009vtu.1_Missense_Mutation_p.D198A|ZCCHC17_uc001bsr.1_Missense_Mutation_p.D222A|ZCCHC17_uc009vtv.1_Missense_Mutation_p.D198A	NM_016505	NP_057589	Q9NP64	NO40_HUMAN	Homo sapiens zinc finger, CCHC domain containing 17 (ZCCHC17), mRNA.	222	Lys-rich.					nucleolus	RNA binding|zinc ion binding			breast(1)|kidney(1)|large_intestine(2)|ovary(1)|skin(1)	6		Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.127)|all_neural(195;0.146)|Medulloblastoma(700;0.151)|Breast(348;0.222)		STAD - Stomach adenocarcinoma(196;0.0215)|READ - Rectum adenocarcinoma(331;0.168)		ACATCAAAAGACAGCAAGGCA	0.433000														92			20		0	0	0.000229342	0	0
IQSEC2	23096	broad.mit.edu	37	X	53268433	53268433	+	Missense_Mutation	SNP	C	G	G			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chrX:53268433C>G	uc004dsd.3	-	10	3260	c.3059G>C	c.(3058-3060)aGt>aCt	p.S1020T	IQSEC2_uc004dsc.3_Missense_Mutation_p.S815T	NM_001111125	NP_001104595	Q5JU85	IQEC2_HUMAN	Homo sapiens IQ motif and Sec7 domain 2 (IQSEC2), transcript variant 1, mRNA.	1010	PH.				regulation of ARF protein signal transduction	cytoplasm	ARF guanyl-nucleotide exchange factor activity			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(4)|lung(10)|ovary(4)|skin(1)	29						CTGACGGAAACTGTACGTCAC	0.502000											OREG0019800	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		7			28		0	0	0.000227799	0	0
DOCK4	9732	broad.mit.edu	37	7	111368620	111368620	+	Missense_Mutation	SNP	C	T	T			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr7:111368620C>T	uc003vfy.3	-	53	6015	c.5746G>A	c.(5746-5748)Gaa>Aaa	p.E1916K	DOCK4_uc011kml.2_Missense_Mutation_p.E752K|DOCK4_uc011kmm.2_Missense_Mutation_p.E740K|DOCK4_uc003vfw.3_Missense_Mutation_p.E1283K|DOCK4_uc003vfx.3_Missense_Mutation_p.E1871K|DOCK4_uc003vfv.3_Missense_Mutation_p.E184K	NM_014705	NP_055520	Q8N1I0	DOCK4_HUMAN	Homo sapiens dedicator of cytokinesis 4 (DOCK4), mRNA.	1871	Pro-rich.				cell chemotaxis	cytosol|endomembrane system|membrane|stereocilium	GTP binding|PDZ domain binding|Rac GTPase activator activity|Rac GTPase binding|SH3 domain binding|guanyl-nucleotide exchange factor activity|receptor tyrosine kinase binding			NS(1)|breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(4)|kidney(4)|large_intestine(13)|lung(31)|ovary(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(4)	72		Acute lymphoblastic leukemia(1;0.0441)				GCCGACTGTTCATTCACCTGA	0.632000														92			8		0	0	3.86212e-05	0	0
C1QTNF2	114898	broad.mit.edu	37	5	159781881	159781881	+	Silent	SNP	G	A	A			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr5:159781881G>A	uc003lyd.3	-	1	277	c.273C>T	c.(271-273)ggC>ggT	p.G91G		NM_031908	NP_114114	Q9BXJ5	C1QT2_HUMAN	Homo sapiens C1q and tumor necrosis factor related protein 2 (C1QTNF2), mRNA.	46	Collagen-like.					collagen				breast(2)|endometrium(2)|large_intestine(1)|lung(4)|prostate(1)|skin(3)	13	Renal(175;0.00196)	Medulloblastoma(196;0.0354)|all_neural(177;0.116)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			CTCCTGGGGGGCCGGGTGGGC	0.682000														12			9		0	0	2.17888e-05	0	0
LOC731275	731275	broad.mit.edu	37	1	243251423	243251423	+	RNA	DEL	A	-	-			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr1:243251423delA	uc001hzq.2	-	7		c.1209delT								Homo sapiens uncharacterized LOC731275 (LOC731275), non-coding RNA.																		actccatctcaaaaaaaaaaa	0.458													---	4	---	---	3	---					
C9orf84	158401	broad.mit.edu	37	9	114454268	114454270	+	In_Frame_Del	DEL	CTC	-	-			TCGA-DZ-6131-01A-11D-1961-08	TCGA-DZ-6131-11A-01D-1961-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	29368ff9-9921-468b-89e7-f004ec2ddb39	3e6c0c90-5ee6-4ec6-ba68-59aae72c362c	g.chr9:114454268_114454270delCTC	uc004bfr.3	-	24	3930_3932	c.3795_3797delGAG	c.(3793-3798)aggaga>aga	p.1265_1266RR>R	C9orf84_uc011lwt.2_Non-coding_Transcript|C9orf84_uc004bfq.3_In_Frame_Del_p.1226_1227RR>R|C9orf84_uc010mug.3_In_Frame_Del_p.1176_1177RR>R	NM_173521	NP_775792	Q5VXU9	CI084_HUMAN	Homo sapiens chromosome 9 open reading frame 84 (C9orf84), transcript variant 1, mRNA.	1265										breast(1)|cervix(1)|endometrium(3)|kidney(7)|large_intestine(10)|liver(1)|lung(7)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	35						TTCATGTGTTCTCCTTTTCTGAG	0.369													---	46	---	---	10	---					
