Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KEAP1	9817	broad.mit.edu	37	19	10600426	10600426	+	Missense_Mutation	SNP	C	T	T			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr19:10600426C>T	uc002moq.1	-	3	1585	c.1429G>A	c.(1429-1431)Ggc>Agc	p.G477S	KEAP1_uc002mop.1_Missense_Mutation_p.G195S|KEAP1_uc002mor.1_Missense_Mutation_p.G477S	NM_012289	NP_987096	Q14145	KEAP1_HUMAN	Homo sapiens kelch-like ECH-associated protein 1 (KEAP1), transcript variant 2, mRNA.	477					regulation of transcription, DNA-dependent|transcription, DNA-dependent	centrosome|midbody|nucleus	protein binding			breast(3)|endometrium(2)|kidney(4)|large_intestine(4)|liver(2)|lung(69)|ovary(2)|pancreas(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	92			OV - Ovarian serous cystadenocarcinoma(20;2.71e-09)|Epithelial(33;2.32e-06)|all cancers(31;1.42e-05)			CCGTCAAAGCCCCCCACGGCA	0.577000														8			12		0	0	1	0	0
MIR876	100126310	broad.mit.edu	37	9	28863696	28863696	+	RNA	SNP	A	C	C			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr9:28863696A>C	uc022bfd.1	-	0		c.9T>G								Homo sapiens microRNA 876 (MIR876), microRNA.																		AGAAATCCACAGCACTTCACA	0.403000														27			14		0	0	1	0	0
ABP1	26	broad.mit.edu	37	7	150554081	150554081	+	Nonsense_Mutation	SNP	C	T	T			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr7:150554081C>T	uc003why.1	+	2	4741	c.523C>T	c.(523-525)Caa>Taa	p.Q175*	ABP1_uc003whz.1_Nonsense_Mutation_p.Q175*|ABP1_uc003wia.1_Nonsense_Mutation_p.Q175*	NM_001091	NP_001082	P19801	ABP1_HUMAN	Homo sapiens amiloride binding protein 1 (amine oxidase (copper-containing)) (ABP1), mRNA.	175					amine metabolic process	extracellular space|peroxisome	copper ion binding|diamine oxidase activity|heparin binding|histamine oxidase activity|methylputrescine oxidase activity|primary amine oxidase activity|propane-1,3-diamine oxidase activity|quinone binding			NS(1)|breast(4)|endometrium(2)|kidney(4)|large_intestine(3)|lung(18)|ovary(3)|prostate(2)|skin(3)|stomach(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	45	all_neural(206;0.219)		OV - Ovarian serous cystadenocarcinoma(82;0.0121)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)	Amiloride(DB00594)|Spermine(DB00127)	CTTCTCATTCCAAGACTGCCA	0.582000														111			40		0	0	1	0	0
ERAL1	26284	broad.mit.edu	37	17	27182067	27182067	+	Silent	SNP	C	T	T			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr17:27182067C>T	uc002hcy.1	+	0	25	c.15C>T	c.(13-15)agC>agT	p.S5S	ERAL1_uc002hcx.1_Silent_p.S5S|ERAL1_uc002hcz.1_Non-coding_Transcript|ERAL1_uc002hda.1_5'Flank	NM_005702	NP_005693	O75616	ERAL1_HUMAN	Homo sapiens Era G-protein-like 1 (E. coli) (ERAL1), mRNA.	5					ribosomal small subunit assembly	mitochondrial inner membrane|mitochondrial matrix	GTP binding|rRNA binding|ribosomal small subunit binding			endometrium(1)|kidney(1)|large_intestine(2)|lung(5)|skin(2)	11	all_cancers(5;2.12e-15)|all_epithelial(6;3.44e-19)|Lung NSC(42;0.01)		Epithelial(11;1.12e-05)|all cancers(11;5.32e-05)|BRCA - Breast invasive adenocarcinoma(11;0.000272)|OV - Ovarian serous cystadenocarcinoma(11;0.105)			CTGCCCCCAGCTGGCGCGGGG	0.612000														26			5		0	0	1	0	0
CDH12	1010	broad.mit.edu	37	5	21842341	21842341	+	Missense_Mutation	SNP	C	T	T			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr5:21842341C>T	uc010iuc.2	-	4	1201	c.743G>A	c.(742-744)gGa>gAa	p.G248E	CDH12_uc011cno.1_Missense_Mutation_p.G208E|CDH12_uc003jgk.2_Missense_Mutation_p.G248E	NM_004061	NP_004052	P55289	CAD12_HUMAN	Homo sapiens cadherin 12, type 2 (N-cadherin 2) (CDH12), mRNA.	248	Cadherin 2.				adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			NS(2)|breast(2)|cervix(1)|endometrium(6)|kidney(4)|large_intestine(19)|lung(75)|ovary(2)|prostate(3)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	120						TCCGGCTAATCCTCCAAGCTG	0.423000										HNSCC(59;0.17)				163			9		0	0	1	0	0
LGALS13	29124	broad.mit.edu	37	19	40095966	40095966	+	Missense_Mutation	SNP	G	A	A			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr19:40095966G>A	uc002omb.3	+	2	281	c.241G>A	c.(241-243)Gtg>Atg	p.V81M		NM_013268	NP_037400	Q9UHV8	PP13_HUMAN	Homo sapiens lectin, galactoside-binding, soluble, 13 (LGALS13), mRNA.	81	Galectin.				lipid catabolic process|phospholipid metabolic process		carboxylesterase activity|lysophospholipase activity|sugar binding			lung(5)|ovary(1)|urinary_tract(1)	7	all_cancers(60;1.77e-05)|all_lung(34;5.38e-08)|Lung NSC(34;6.37e-08)|Ovarian(47;0.116)		Epithelial(26;3.28e-26)|OV - Ovarian serous cystadenocarcinoma(5;7.31e-25)|all cancers(26;1.15e-23)|LUSC - Lung squamous cell carcinoma(53;0.00281)			AACAGACTACGTGCCCTTTGA	0.493000														47			31		0	0	1	0	0
GNAT1	2779	broad.mit.edu	37	3	50230803	50230803	+	Silent	SNP	C	T	T			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr3:50230803C>T	uc003cym.2	+	2	371	c.255C>T	c.(253-255)acC>acT	p.T85T	GNAT1_uc003cyl.2_Silent_p.T85T	NM_144499	NP_653082	P11488	GNAT1_HUMAN	Homo sapiens guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 (GNAT1), transcript variant 1, mRNA.	85					G-protein signaling, coupled to cAMP nucleotide second messenger|detection of chemical stimulus involved in sensory perception of bitter taste|negative regulation of cyclic-nucleotide phosphodiesterase activity|rhodopsin mediated phototransduction|sensory perception of umami taste	heterotrimeric G-protein complex|photoreceptor inner segment|photoreceptor outer segment membrane	G-protein beta/gamma-subunit complex binding|G-protein-coupled receptor binding|GDP binding|GTP binding|GTPase activity|acyl binding|protein kinase binding|signal transducer activity			central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(3)|lung(4)|ovary(2)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	17				BRCA - Breast invasive adenocarcinoma(193;0.000272)|KIRC - Kidney renal clear cell carcinoma(197;0.00544)|Kidney(197;0.00605)		GCGCCATGACCACACTCAACA	0.637000														31			8		0	0	1	0	0
NFKBID	84807	broad.mit.edu	37	19	36387021	36387021	+	Missense_Mutation	SNP	G	A	A			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr19:36387021G>A	uc002oci.1	-	8	1041	c.467C>T	c.(466-468)cCg>cTg	p.P156L	NFKBID_uc002och.1_5'UTR	NM_139239	NP_640332	Q8NI38	IKBD_HUMAN	Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta (NFKBID), mRNA.	156					inflammatory response	nucleus				breast(1)|cervix(1)|endometrium(2)|large_intestine(2)|lung(6)|ovary(1)|urinary_tract(1)	14						CGTGTGGAGCGGGGTGAGGCC	0.647000														75			9		0	0	1	0	0
MSI1	4440	broad.mit.edu	37	12	120805884	120805884	+	Frame_Shift_Del	DEL	A	-	-			TCGA-BJ-A192-01A-31D-A13W-08	TCGA-BJ-A192-10A-01D-A13W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d79a268-fa99-488e-ac9a-24e7adef76bc	05f2dae1-eff1-46b9-ada8-423cb1cdb118	g.chr12:120805884delA	uc001tye.1	-	3	258	c.194delT	c.(193-195)ttcfs	p.F65fs		NM_002442	NP_002433	O43347	MSI1H_HUMAN	Homo sapiens musashi homolog 1 (Drosophila) (MSI1), mRNA.	65	RRM 1.				nervous system development	cytoplasm|nucleus	nucleotide binding	p.F65F(1)		breast(4)|central_nervous_system(2)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(1)|lung(5)|skin(2)	19	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)					GAAAGTGACGAAGCCGAAACC	0.657													---	11	---	---	9	---					
