Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
TNNT3	7140	broad.mit.edu	37	11	1956128	1956128	+	Missense_Mutation	SNP	G	C	C			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr11:1956128G>C	uc001luu.4	+	13	872	c.660G>C	c.(658-660)aaG>aaC	p.K220N	TNNT3_uc001lun.2_Missense_Mutation_p.K116N|TNNT3_uc001luw.4_Missense_Mutation_p.K212N|TNNT3_uc001luo.4_Missense_Mutation_p.K212N|TNNT3_uc001lup.4_Missense_Mutation_p.K218N|TNNT3_uc001luq.4_Missense_Mutation_p.K212N|TNNT3_uc001lur.3_Missense_Mutation_p.K212N|TNNT3_uc010qxf.2_Missense_Mutation_p.K218N|TNNT3_uc010qxg.2_Missense_Mutation_p.K152N	NM_006757	NP_006748	P45378	TNNT3_HUMAN	Homo sapiens troponin T type 3 (skeletal, fast) (TNNT3), transcript variant 1, mRNA.	231					muscle filament sliding|regulation of ATPase activity|regulation of striated muscle contraction|skeletal muscle contraction	cytosol|troponin complex	calcium-dependent protein binding|tropomyosin binding|troponin C binding|troponin I binding			breast(2)|endometrium(1)|kidney(1)|lung(8)|ovary(1)|prostate(1)|skin(4)|stomach(1)	19		all_epithelial(84;0.000138)|Breast(177;0.000962)|Ovarian(85;0.0014)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.229)		BRCA - Breast invasive adenocarcinoma(625;0.00253)|Lung(200;0.0333)|LUSC - Lung squamous cell carcinoma(625;0.0826)		TTGGGGAGAAGCTGAAACGCC	0.612000														108			31		0	0	1	0	0
MAN1A1	4121	broad.mit.edu	37	6	119569448	119569448	+	Silent	SNP	A	C	C			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr6:119569448A>C	uc003pym.1	-	5	1411	c.969T>G	c.(967-969)ccT>ccG	p.P323P	MAN1A1_uc010kei.2_Silent_p.P346P	NM_005907	NP_005898	P33908	MA1A1_HUMAN	Homo sapiens mannosidase, alpha, class 1A, member 1 (MAN1A1), mRNA.	323					post-translational protein modification|protein N-linked glycosylation via asparagine	ER-Golgi intermediate compartment|Golgi membrane|endoplasmic reticulum|integral to membrane|membrane fraction	calcium ion binding|mannosyl-oligosaccharide 1,2-alpha-mannosidase activity			central_nervous_system(1)|endometrium(2)|large_intestine(6)|lung(8)|ovary(2)|prostate(2)|skin(3)	24		all_epithelial(87;0.173)		OV - Ovarian serous cystadenocarcinoma(136;0.0612)|GBM - Glioblastoma multiforme(226;0.0702)|all cancers(137;0.115)		GCAATGCCCAAGGTATTCCAG	0.343000														29			10		0	0	1	0	0
AGPAT6	137964	broad.mit.edu	37	8	41470442	41470442	+	Missense_Mutation	SNP	C	T	T			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr8:41470442C>T	uc003xnz.2	+	7	1813	c.874C>T	c.(874-876)Cgc>Tgc	p.R292C		NM_178819	NP_848934	Q86UL3	GPAT4_HUMAN	Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) (AGPAT6), mRNA.	292					acyl-CoA metabolic process|lactation|phosphatidylcholine biosynthetic process|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane|membrane fraction	glycerol-3-phosphate O-acyltransferase activity			endometrium(3)|kidney(2)|large_intestine(3)|lung(6)	14	Ovarian(28;0.00769)|Colorectal(14;0.0202)|Lung SC(25;0.211)	all_lung(54;0.0131)|Lung NSC(58;0.0363)|Hepatocellular(245;0.0462)|Esophageal squamous(32;0.0844)	OV - Ovarian serous cystadenocarcinoma(14;0.00126)|Colorectal(10;0.0014)|Lung(22;0.00177)|LUSC - Lung squamous cell carcinoma(45;0.00392)|COAD - Colon adenocarcinoma(11;0.0147)			CTGGTTTGAGCGCTCGGAAGT	0.552000											OREG0018739	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		14			5		0	0	1	0	0
KRT9	3857	broad.mit.edu	37	17	39725743	39725743	+	Missense_Mutation	SNP	G	A	A			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr17:39725743G>A	uc002hxe.4	-	3	1045	c.979C>T	c.(979-981)Cgt>Tgt	p.R327C	JUP_uc010wfs.2_Intron	NM_000226	NP_000217	P35527	K1C9_HUMAN	Homo sapiens keratin 9 (KRT9), mRNA.	327	Coil 2.|Rod.				intermediate filament organization|skin development		protein binding|structural constituent of cytoskeleton	p.R327H(1)		autonomic_ganglia(1)|breast(2)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|lung(4)|ovary(1)|pancreas(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	25		Breast(137;0.000307)				TACTCCTGACGCATGTCATTG	0.502000														47			9		0	0	1	0	0
GPR101	83550	broad.mit.edu	37	X	136112376	136112376	+	Missense_Mutation	SNP	G	T	T			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chrX:136112376G>T	uc011mwh.2	-	0	1458	c.1458C>A	c.(1456-1458)gaC>gaA	p.D486E		NM_054021	NP_473362	Q96P66	GP101_HUMAN	Homo sapiens G protein-coupled receptor 101 (GPR101), mRNA.	486						integral to membrane|plasma membrane	G-protein coupled receptor activity			autonomic_ganglia(1)|endometrium(5)|kidney(2)|large_intestine(11)|lung(18)|ovary(3)|skin(1)|urinary_tract(1)	42	Acute lymphoblastic leukemia(192;0.000127)					TTCCGGGCAGGTCTGGGTGGC	0.478000														77			22		1.87028e-06	1.87028e-06	1	1	0
PHKA2	5256	broad.mit.edu	37	X	18913268	18913268	+	Silent	SNP	C	T	T			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chrX:18913268C>T	uc004cyv.4	-	30	3754	c.3324G>A	c.(3322-3324)tcG>tcA	p.S1108S	PHKA2_uc010nfe.1_Silent_p.S140S|PHKA2_uc010nff.1_Non-coding_Transcript	NM_000292	NP_000283	P46019	KPB2_HUMAN	Homo sapiens phosphorylase kinase, alpha 2 (liver) (PHKA2), mRNA.	1108					glucose metabolic process|glycogen catabolic process	cytosol|phosphorylase kinase complex|plasma membrane	calmodulin binding|glucan 1,4-alpha-glucosidase activity|phosphorylase kinase activity			NS(1)|biliary_tract(1)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(8)|kidney(1)|large_intestine(12)|lung(23)|ovary(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	61	Hepatocellular(33;0.183)					CTCGGGTCGTCGAGGATGGGA	0.527000														89			25		0	0	1	0	0
AGPAT6	137964	broad.mit.edu	37	8	41470441	41470441	+	Silent	SNP	G	A	A			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr8:41470441G>A	uc003xnz.2	+	7	1812	c.873G>A	c.(871-873)gaG>gaA	p.E291E		NM_178819	NP_848934	Q86UL3	GPAT4_HUMAN	Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta) (AGPAT6), mRNA.	291					acyl-CoA metabolic process|lactation|phosphatidylcholine biosynthetic process|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane|membrane fraction	glycerol-3-phosphate O-acyltransferase activity			endometrium(3)|kidney(2)|large_intestine(3)|lung(6)	14	Ovarian(28;0.00769)|Colorectal(14;0.0202)|Lung SC(25;0.211)	all_lung(54;0.0131)|Lung NSC(58;0.0363)|Hepatocellular(245;0.0462)|Esophageal squamous(32;0.0844)	OV - Ovarian serous cystadenocarcinoma(14;0.00126)|Colorectal(10;0.0014)|Lung(22;0.00177)|LUSC - Lung squamous cell carcinoma(45;0.00392)|COAD - Colon adenocarcinoma(11;0.0147)			TCTGGTTTGAGCGCTCGGAAG	0.547000											OREG0018739	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		14			5		0	0	1	0	0
GPR4	2828	broad.mit.edu	37	19	46094655	46094655	+	Missense_Mutation	SNP	T	A	A			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr19:46094655T>A	uc002pcm.3	-	1	1415	c.470A>T	c.(469-471)gAg>gTg	p.E157V	OPA3_uc010xxk.2_Intron|GPR4_uc021uvw.1_Missense_Mutation_p.E157V	NM_005282	NP_005273	P46093	GPR4_HUMAN	Homo sapiens G protein-coupled receptor 4 (GPR4), mRNA.	157						integral to plasma membrane	G-protein coupled receptor activity			breast(2)|endometrium(1)|kidney(3)|large_intestine(1)|lung(11)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	23				OV - Ovarian serous cystadenocarcinoma(262;0.0071)|GBM - Glioblastoma multiforme(486;0.128)|Epithelial(262;0.223)		TCGGAAGAGCTCGTCATGGAA	0.652000														85			11		0	0	1	0	0
PELI1	57162	broad.mit.edu	37	2	64323399	64323399	+	Missense_Mutation	SNP	T	C	C			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr2:64323399T>C	uc002scs.4	-	4	4589	c.550A>G	c.(550-552)Acc>Gcc	p.T184A	PELI1_uc002sct.4_Missense_Mutation_p.T184A|PELI1_uc002scr.4_Missense_Mutation_p.T5A	NM_020651	NP_065702	Q96FA3	PELI1_HUMAN	Homo sapiens pellino homolog 1 (Drosophila) (PELI1), mRNA.	184					MyD88-dependent toll-like receptor signaling pathway|Toll signaling pathway|innate immune response|positive regulation of I-kappaB kinase/NF-kappaB cascade|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway	cytosol				central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(9)|ovary(1)|urinary_tract(1)	19						CCATTAGTGGTCAAGCCATCC	0.428000														66			5		0	0	1	0	0
GJA3	2700	broad.mit.edu	37	13	20716349	20716349	+	Frame_Shift_Del	DEL	G	-	-			TCGA-EL-A4JX-01A-12D-A257-08	TCGA-EL-A4JX-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8fc9f8a6-5a37-4f2b-b160-6e1f06a433dd	7edd3289-ff98-4237-a5bf-a3ece719e294	g.chr13:20716349delG	uc001umx.1	-	1	1251	c.1079delC	c.(1078-1080)ccgfs	p.P360fs	GJA3_uc021rgz.1_Frame_Shift_Del_p.P360fs	NM_021954	NP_068773	Q9Y6H8	CXA3_HUMAN	Homo sapiens gap junction protein, alpha 3, 46kDa (GJA3), mRNA.	360					cell-cell signaling|visual perception	connexon complex|integral to membrane				NS(1)|endometrium(1)|kidney(1)|lung(1)|pancreas(1)|prostate(1)|skin(1)	7		all_cancers(29;1.4e-21)|all_epithelial(30;8.75e-19)|all_lung(29;1.28e-17)|Lung SC(185;0.0257)|Ovarian(182;0.0822)		all cancers(112;0.000554)|Epithelial(112;0.000872)|OV - Ovarian serous cystadenocarcinoma(117;0.0105)|Lung(94;0.0251)|LUSC - Lung squamous cell carcinoma(192;0.0784)		CGCGAGTGGCGGGGAGCTGCT	0.766													---	4	---	---	2	---					
