Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MBD5	55777	broad.mit.edu	37	2	149226187	149226187	+	Silent	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr2:149226187G>A	uc002twm.4	+	8	1672	c.675G>A	c.(673-675)gcG>gcA	p.A225A	MBD5_uc010zbs.2_Non-coding_Transcript|MBD5_uc002twn.1_5'Flank	NM_018328	NP_060798	Q9P267	MBD5_HUMAN	Homo sapiens methyl-CpG binding domain protein 5 (MBD5), mRNA.	225						chromosome|nucleus	DNA binding|chromatin binding			NS(1)|breast(4)|central_nervous_system(1)|endometrium(8)|kidney(1)|large_intestine(16)|lung(22)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(3)	62				BRCA - Breast invasive adenocarcinoma(221;0.0569)		CCAGCCCAGCGTCATCAGGTT	0.512000														87			5		0	0	1	0	0
PEF1	553115	broad.mit.edu	37	1	32101118	32101118	+	Silent	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr1:32101118G>A	uc001bth.2	-	1	403	c.30C>T	c.(28-30)tgC>tgT	p.C10C	PEF1_uc021okp.1_5'UTR|PEF1_uc021okq.1_Intron|PEF1_uc001bte.1_5'Flank|PEF1_uc010ogm.2_Silent_p.C10C	NM_012392	NP_036524	Q9UBV8	PEF1_HUMAN	Homo sapiens penta-EF-hand domain containing 1 (PEF1), transcript variant 1, mRNA.	10					response to calcium ion	cytoplasm|membrane	calcium ion binding|protein heterodimerization activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|lung(1)|prostate(2)|upper_aerodigestive_tract(1)	7		Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.104)|all_neural(195;0.186)		STAD - Stomach adenocarcinoma(196;0.0546)		CAGCTCCTGGGCAGCCCTGCA	0.562000														45			3		0	0	1	0	0
DSCAML1	57453	broad.mit.edu	37	11	117392079	117392079	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr11:117392079C>T	uc001prh.1	-	5	1161	c.1159G>A	c.(1159-1161)Ggc>Agc	p.G387S	DSCAML1_uc001pri.1_Missense_Mutation_p.G191S	NM_020693	NP_065744	Q8TD84	DSCL1_HUMAN	Homo sapiens Down syndrome cell adhesion molecule like 1 (DSCAML1), mRNA.	327	Ig-like C2-type 4.				axonogenesis|brain development|cell fate determination|dorsal/ventral pattern formation|embryonic skeletal system morphogenesis|homophilic cell adhesion	cell surface|integral to membrane|plasma membrane	protein homodimerization activity			breast(3)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(3)|kidney(7)|large_intestine(24)|lung(49)|ovary(6)|pancreas(1)|prostate(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	110	all_hematologic(175;0.0487)	Breast(348;0.0424)|Medulloblastoma(222;0.0523)|all_hematologic(192;0.232)		BRCA - Breast invasive adenocarcinoma(274;9.12e-06)|Epithelial(105;0.00172)		CTGCCAATGCCGGTCTTCAGC	0.607000														44			3		0	0	1	0	0
PKD2	5311	broad.mit.edu	37	4	88986631	88986631	+	Nonsense_Mutation	SNP	C	T	T	rs121918040		TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr4:88986631C>T	uc003hre.3	+	10	2311	c.2224C>T	c.(2224-2226)Cga>Tga	p.R742*	PKD2_uc011cdf.2_Nonsense_Mutation_p.R160*|PKD2_uc011cdg.2_Nonsense_Mutation_p.R68*|PKD2_uc011cdh.2_5'UTR	NM_000297	NP_000288	Q13563	PKD2_HUMAN	Homo sapiens polycystic kidney disease 2 (autosomal dominant) (PKD2), mRNA.	742	EF-hand domain.					basal cortex|basal plasma membrane|endoplasmic reticulum|integral to membrane|lamellipodium|microtubule basal body	calcium ion binding|cytoskeletal protein binding|voltage-gated chloride channel activity|voltage-gated sodium channel activity	p.R742*(2)		breast(1)|endometrium(4)|kidney(1)|large_intestine(8)|liver(2)|lung(15)|skin(4)|upper_aerodigestive_tract(1)	36		Hepatocellular(203;0.114)|Acute lymphoblastic leukemia(40;0.221)		OV - Ovarian serous cystadenocarcinoma(123;9.98e-10)|COAD - Colon adenocarcinoma(81;0.0237)		TGACGAACTTCGACAAGATCT	0.403000														99			89		0	0	1	0	0
NPTX2	4885	broad.mit.edu	37	7	98254299	98254299	+	Missense_Mutation	SNP	T	G	G			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr7:98254299T>G	uc003upl.2	+	2	886	c.709T>G	c.(709-711)Tac>Gac	p.Y237D		NM_002523	NP_002514	P47972	NPTX2_HUMAN	Homo sapiens neuronal pentraxin II (NPTX2), mRNA.	237	Pentaxin.				synaptic transmission	extracellular region	metal ion binding|sugar binding			breast(1)|central_nervous_system(2)|endometrium(1)|large_intestine(5)|lung(5)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	18	all_cancers(62;2.28e-09)|all_epithelial(64;4.86e-10)|Esophageal squamous(72;0.00918)|Lung NSC(181;0.0128)|all_lung(186;0.0142)		STAD - Stomach adenocarcinoma(171;0.215)			AAACTACCTATACGGCAAGAT	0.587000														45			44		0	0	1	0	0
SMARCA2	6595	broad.mit.edu	37	9	2056812	2056812	+	Silent	SNP	T	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr9:2056812T>A	uc003zhc.3	+	6	1413	c.1314T>A	c.(1312-1314)atT>atA	p.I438I	SMARCA2_uc003zhd.3_Silent_p.I438I|SMARCA2_uc010mha.3_Silent_p.I429I	NM_003070	NP_003061	P51531	SMCA2_HUMAN	Homo sapiens SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2), transcript variant 1, mRNA.	438	HSA.				chromatin remodeling|negative regulation of cell growth|negative regulation of transcription from RNA polymerase II promoter|nervous system development	SWI/SNF complex|WINAC complex|intermediate filament cytoskeleton|nBAF complex|npBAF complex|nuclear chromatin|nucleoplasm	ATP binding|DNA-dependent ATPase activity|RNA polymerase II transcription coactivator activity|helicase activity|protein binding|transcription regulatory region DNA binding			breast(1)|central_nervous_system(1)|endometrium(7)|kidney(3)|large_intestine(11)|liver(2)|lung(19)|ovary(3)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	56		all_lung(10;2.06e-09)|Lung NSC(10;2.43e-09)		GBM - Glioblastoma multiforme(50;0.0475)		AGCAGAAGATTGAGCAGGAGA	0.532000														36			28		0	0	1	0	0
LSM14A	26065	broad.mit.edu	37	19	34712450	34712450	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr19:34712450A>G	uc002nvb.4	+	8	1371	c.1175A>G	c.(1174-1176)aAt>aGt	p.N392S	LSM14A_uc002nva.4_Missense_Mutation_p.N392S|LSM14A_uc010xru.2_Missense_Mutation_p.N351S|LSM14A_uc002nvc.4_Missense_Mutation_p.N198S	NM_001114093	NP_001107565	Q8ND56	LS14A_HUMAN	Homo sapiens LSM14A, SCD6 homolog A (S. cerevisiae) (LSM14A), transcript variant 1, mRNA.	392					cytoplasmic mRNA processing body assembly|multicellular organismal development|regulation of translation	cytoplasmic mRNA processing body|intracellular membrane-bounded organelle|stress granule		p.N392S(2)		breast(1)|endometrium(4)|kidney(1)|large_intestine(8)|lung(7)|skin(1)	22	Esophageal squamous(110;0.162)					AGAAGATTAAATGCTGAAACA	0.463000														81			53		0	0	1	0	0
AKAP12	9590	broad.mit.edu	37	6	151673069	151673069	+	Silent	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr6:151673069C>T	uc011eep.2	+	3	3783	c.3543C>T	c.(3541-3543)gaC>gaT	p.D1181D	AKAP12_uc003qoe.3_Silent_p.D1181D|AKAP12_uc003qof.3_Silent_p.D1083D|AKAP12_uc010kim.3_Intron|AKAP12_uc003qog.3_Silent_p.D1076D	NM_005100	NP_005091	Q02952	AKA12_HUMAN	Homo sapiens A kinase (PRKA) anchor protein 12 (AKAP12), transcript variant 1, mRNA.	1181					G-protein coupled receptor protein signaling pathway|positive regulation of cAMP biosynthetic process|positive regulation of protein kinase A signaling cascade|protein targeting	cell cortex|cytoskeleton|plasma membrane	adenylate cyclase binding|protein kinase A binding	p.D1181D(2)		breast(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(22)|lung(22)|ovary(2)|pancreas(1)|prostate(2)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	68		Ovarian(120;0.125)	BRCA - Breast invasive adenocarcinoma(37;0.175)	OV - Ovarian serous cystadenocarcinoma(155;2.98e-11)		CCGACTTTGACGCACCAGGCA	0.552000														24			6		0	0	1	0	0
OR13C2	392376	broad.mit.edu	37	9	107367649	107367649	+	Nonsense_Mutation	SNP	G	C	C			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr9:107367649G>C	uc011lvq.2	-	0	260	c.260C>G	c.(259-261)tCa>tGa	p.S87*		NM_001004481	NP_001004481	Q8NGS9	O13C2_HUMAN	Homo sapiens olfactory receptor, family 13, subfamily C, member 2 (OR13C2), mRNA.	87					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			cervix(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(10)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	22						CTTTCTTTCTGAAAGGAAGCT	0.517000														352			36		0	0	1	0	0
CCDC66	285331	broad.mit.edu	37	3	56649272	56649272	+	Silent	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr3:56649272C>T	uc003dhz.3	+	11	1770	c.1683C>T	c.(1681-1683)gaC>gaT	p.D561D	CCDC66_uc003dhy.3_Silent_p.D197D|CCDC66_uc003dhu.3_Silent_p.D527D|CCDC66_uc003dhx.3_Non-coding_Transcript|CCDC66_uc003dia.3_5'Flank	NM_001141947	NP_001135419	A2RUB6	CCD66_HUMAN	Homo sapiens coiled-coil domain containing 66 (CCDC66), transcript variant 1, mRNA.	561										breast(1)|kidney(1)|large_intestine(2)|liver(1)|lung(4)|skin(2)|urinary_tract(1)	12				KIRC - Kidney renal clear cell carcinoma(284;0.0478)|Kidney(284;0.0597)|OV - Ovarian serous cystadenocarcinoma(275;0.233)		AGGGACATGACACTTCTAGAC	0.358000														191			169		0	0	1	0	0
KIAA1199	57214	broad.mit.edu	37	15	81216982	81216982	+	Silent	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr15:81216982C>T	uc002bfw.1	+	16	2483	c.2223C>T	c.(2221-2223)aaC>aaT	p.N741N	KIAA1199_uc010unn.1_Silent_p.N741N	NM_018689	NP_061159	Q8WUJ3	K1199_HUMAN	Homo sapiens KIAA1199 (KIAA1199), mRNA.	741										breast(4)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(10)|lung(14)|ovary(1)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	49						TCATAGACAACGGAGTCAAAA	0.527000														112			8		0	0	1	0	0
GALNT6	11226	broad.mit.edu	37	12	51752937	51752937	+	Missense_Mutation	SNP	C	G	G			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr12:51752937C>G	uc001ryk.2	-	6	1572	c.1347G>C	c.(1345-1347)caG>caC	p.Q449H	GALNT6_uc009zma.1_Non-coding_Transcript|GALNT6_uc001ryl.1_Missense_Mutation_p.Q449H|GALNT6_uc001ryj.1_Missense_Mutation_p.Q14H	NM_007210	NP_009141	Q8NCL4	GALT6_HUMAN	Homo sapiens UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) (GALNT6), mRNA.	449					protein O-linked glycosylation	Golgi membrane|integral to membrane|perinuclear region of cytoplasm	polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			endometrium(2)|large_intestine(6)|lung(7)|ovary(3)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	27						TCTTTGCTGCCTGCAGATTTC	0.522000														55			5		0	0	1	0	0
ZNF187	7741	broad.mit.edu	37	6	28240025	28240025	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr6:28240025G>A	uc011dlc.2	+	2	596	c.326G>A	c.(325-327)cGg>cAg	p.R109Q	ZNF187_uc003nku.4_Intron|ZNF187_uc003nkw.4_5'UTR|ZNF187_uc011dle.2_5'UTR|ZNF187_uc011dlf.2_Intron|ZNF187_uc011dld.2_Missense_Mutation_p.R109Q|ZNF187_uc011dlg.2_5'UTR	NM_001023560	NP_001018854	Q16670	ZN187_HUMAN	Homo sapiens zinc finger protein 187 (ZNF187), transcript variant a, mRNA.	110	SCAN box.				viral reproduction	nucleus	nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding										CTCCAGGCCCGGGTGCAGGAG	0.567000														46			5		0	0	1	0	0
BCLAF1	9774	broad.mit.edu	37	6	136599231	136599231	+	Missense_Mutation	SNP	T	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr6:136599231T>A	uc003qgx.1	-	3	1041	c.788A>T	c.(787-789)cAt>cTt	p.H263L	BCLAF1_uc003qgy.1_Missense_Mutation_p.H261L|BCLAF1_uc011edc.1_Non-coding_Transcript|BCLAF1_uc011edd.1_Non-coding_Transcript|BCLAF1_uc011ede.1_Missense_Mutation_p.H261L|BCLAF1_uc003qgw.1_Missense_Mutation_p.H263L	NM_014739	NP_055554	Q9NYF8	BCLF1_HUMAN	Homo sapiens BCL2-associated transcription factor 1 (BCLAF1), transcript variant 1, mRNA.	263					induction of apoptosis|negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleolus	DNA binding|protein binding			haematopoietic_and_lymphoid_tissue(3)|large_intestine(4)|ovary(1)|skin(1)	9	Colorectal(23;0.24)			GBM - Glioblastoma multiforme(68;0.00226)|OV - Ovarian serous cystadenocarcinoma(155;0.00331)		CTGAATGGAATGTGAATGCTG	0.443000														133			57		0	0	1	0	0
TM4SF4	7104	broad.mit.edu	37	3	149192812	149192812	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr3:149192812G>A	uc003exd.2	+	0	445	c.148G>A	c.(148-150)Gga>Aga	p.G50R		NM_004617	NP_004608	P48230	T4S4_HUMAN	Homo sapiens transmembrane 4 L six family member 4 (TM4SF4), mRNA.	50						integral to membrane				large_intestine(3)|lung(4)|ovary(1)|prostate(1)	9			LUSC - Lung squamous cell carcinoma(72;0.0378)|Lung(72;0.048)			CTGGTTTTTCGGAGGAATATT	0.428000														56			3		0	0	1	0	0
C14orf142	84520	broad.mit.edu	37	14	93670052	93670052	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr14:93670052C>T	uc001ybl.1	-	1	361	c.284G>A	c.(283-285)cGg>cAg	p.R95Q		NM_032490	NP_115879	Q9BXV9	CN142_HUMAN	Homo sapiens chromosome 14 open reading frame 142 (C14orf142), mRNA.	95										endometrium(1)|skin(1)	2		all_cancers(154;0.00528)|Acute lymphoblastic leukemia(33;0.0497)|all_epithelial(191;0.125)|all_neural(303;0.13)		Epithelial(152;0.177)|all cancers(159;0.198)|COAD - Colon adenocarcinoma(157;0.203)		TGTTTTTGGCCGTTTTGCAGA	0.338000														162			4		0	0	1	0	0
DUSP16	80824	broad.mit.edu	37	12	12630273	12630273	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr12:12630273A>G	uc001rao.2	-	6	2255	c.1492T>C	c.(1492-1494)Tcc>Ccc	p.S498P	DUSP16_uc001ran.2_Missense_Mutation_p.S350P	NM_030640	NP_085143	Q9BY84	DUS16_HUMAN	Homo sapiens dual specificity phosphatase 16 (DUSP16), mRNA.	498					MAPK export from nucleus|MAPK phosphatase export from nucleus, leptomycin B sensitive|inactivation of MAPK activity	cytoplasmic membrane-bounded vesicle|nucleus	MAP kinase tyrosine/serine/threonine phosphatase activity|protein tyrosine phosphatase activity			endometrium(7)|kidney(2)|large_intestine(6)|lung(6)|pancreas(1)|prostate(1)|urinary_tract(3)	26		Prostate(47;0.0687)		BRCA - Breast invasive adenocarcinoma(232;0.0203)		GATAAAAGGGACCTCTGGGCG	0.582000														133			5		0	0	1	0	0
MUSK	4593	broad.mit.edu	37	9	113563201	113563201	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr9:113563201G>A	uc022blv.1	+	14	2677	c.2543G>A	c.(2542-2544)aGt>aAt	p.S848N	MUSK_uc022blt.1_3'UTR|MUSK_uc004bez.2_Missense_Mutation_p.S759N|MUSK_uc022blu.1_Missense_Mutation_p.S749N	NM_005592	NP_005583	O15146	MUSK_HUMAN	Homo sapiens muscle, skeletal, receptor tyrosine kinase (MUSK), transcript variant 1, mRNA.	848	Protein kinase.				transmembrane receptor protein tyrosine kinase signaling pathway	integral to plasma membrane	ATP binding|transmembrane receptor protein tyrosine kinase activity			breast(1)|central_nervous_system(1)|endometrium(7)|kidney(3)|large_intestine(7)|lung(23)|ovary(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)	49						GACAGACCCAGTTTCACCAGT	0.507000														75			4		0	0	1	0	0
CHD4	1108	broad.mit.edu	37	12	6701640	6701640	+	Missense_Mutation	SNP	C	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr12:6701640C>A	uc001qpo.3	-	18	3031	c.2867G>T	c.(2866-2868)cGg>cTg	p.R956L	CHD4_uc001qpn.3_Missense_Mutation_p.R949L|CHD4_uc001qpp.3_Missense_Mutation_p.R953L	NM_001273	NP_001264	Q14839	CHD4_HUMAN	Homo sapiens chromodomain helicase DNA binding protein 4 (CHD4), mRNA.	956					chromatin modification|regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	NuRD complex|microtubule organizing center	ATP binding|ATP-dependent DNA helicase activity|DNA binding|zinc ion binding			central_nervous_system(2)	2						TTTGAGCCGCCGCAACATGTG	0.498000														76			61		1.1794e-34	1.25088e-34	1	1	0
XIRP2	129446	broad.mit.edu	37	2	168100984	168100984	+	Nonsense_Mutation	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr2:168100984C>T	uc002udx.3	+	8	3171	c.3082C>T	c.(3082-3084)Cag>Tag	p.Q1028*	XIRP2_uc010fpn.3_Intron|XIRP2_uc010fpo.3_Intron|XIRP2_uc002udy.3_Nonsense_Mutation_p.Q853*|XIRP2_uc010fpq.3_Nonsense_Mutation_p.Q806*|XIRP2_uc010fpr.3_Intron	NM_152381	NP_689594	A4UGR9	XIRP2_HUMAN	Homo sapiens xin actin-binding repeat containing 2 (XIRP2), transcript variant 1, mRNA.	853					actin cytoskeleton organization	cell junction	actin binding			NS(3)|biliary_tract(2)|breast(5)|cervix(3)|endometrium(16)|haematopoietic_and_lymphoid_tissue(2)|kidney(18)|large_intestine(51)|lung(160)|ovary(7)|pancreas(3)|prostate(11)|skin(14)|stomach(5)|upper_aerodigestive_tract(8)|urinary_tract(7)	315						GCCCATTGACCAGTTTGATGA	0.363000														51			3		0	0	1	0	0
LRRK1	79705	broad.mit.edu	37	15	101606197	101606197	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr15:101606197C>T	uc002bwr.3	+	31	5874	c.5555C>T	c.(5554-5556)gCt>gTt	p.A1852V	LRRK1_uc010usb.2_Non-coding_Transcript|LRRK1_uc010usc.2_Non-coding_Transcript|LRRK1_uc002bws.3_Non-coding_Transcript	NM_024652	NP_078928	Q38SD2	LRRK1_HUMAN	Homo sapiens leucine-rich repeat kinase 1 (LRRK1), mRNA.	1852					small GTPase mediated signal transduction	mitochondrion	ATP binding|GTP binding|metal ion binding|protein binding|protein serine/threonine kinase activity			breast(2)|central_nervous_system(6)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(14)|lung(25)|ovary(4)|prostate(1)|skin(1)	72	Melanoma(26;0.00505)|Lung NSC(78;0.00793)|all_lung(78;0.0094)		OV - Ovarian serous cystadenocarcinoma(32;0.000932)|LUSC - Lung squamous cell carcinoma(107;0.187)|Lung(145;0.23)			CCCCGCCAGGCTGCCAGGTCC	0.597000														124			26		0	0	1	0	0
TACC3	10460	broad.mit.edu	37	4	1729580	1729580	+	Missense_Mutation	SNP	G	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr4:1729580G>T	uc003gdo.3	+	3	606	c.451G>T	c.(451-453)Gac>Tac	p.D151Y	TACC3_uc010ibz.3_Missense_Mutation_p.D151Y|TACC3_uc003gdp.3_Intron	NM_006342	NP_006333	Q9Y6A5	TACC3_HUMAN	Homo sapiens transforming, acidic coiled-coil containing protein 3 (TACC3), mRNA.	151						centrosome				central_nervous_system(1)|endometrium(4)|large_intestine(1)|lung(10)|ovary(4)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	25		Breast(71;0.212)|all_epithelial(65;0.241)	OV - Ovarian serous cystadenocarcinoma(23;0.00765)|Epithelial(3;0.0126)			TGCCCTGGCTGACCTGGACTG	0.602000														93			15		1.02788e-11	1.05812e-11	1	1	0
CNDP1	84735	broad.mit.edu	37	18	72234590	72234590	+	Silent	SNP	T	C	C			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr18:72234590T>C	uc002llq.3	+	5	889	c.678T>C	c.(676-678)atT>atC	p.I226I	CNDP1_uc002lls.3_Silent_p.I29I	NM_032649	NP_116038	Q96KN2	CNDP1_HUMAN	Homo sapiens carnosine dipeptidase 1 (metallopeptidase M20 family) (CNDP1), mRNA.	226					proteolysis	extracellular region	carboxypeptidase activity|dipeptidase activity|metal ion binding|metallopeptidase activity|tripeptidase activity			breast(1)|central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(4)|lung(12)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	27		Esophageal squamous(42;0.129)|Prostate(75;0.157)|Melanoma(33;0.211)		BRCA - Breast invasive adenocarcinoma(31;0.109)		ACATTGTAATTTCAGATAACC	0.493000														137			5		0	0	1	0	0
ZBTB17	7709	broad.mit.edu	37	1	16268583	16268583	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr1:16268583C>T	uc001axl.4	-	15	2532	c.2293G>A	c.(2293-2295)Gcc>Acc	p.A765T	ZBTB17_uc010obs.2_Missense_Mutation_p.A689T|ZBTB17_uc010obq.2_Missense_Mutation_p.A683T|ZBTB17_uc010obr.2_Missense_Mutation_p.A772T	NM_003443	NP_003434	Q13105	ZBT17_HUMAN	Homo sapiens zinc finger and BTB domain containing 17 (ZBTB17), transcript variant 2, mRNA.	765	Interaction with HCFC1.				negative regulation of cell cycle	nucleus	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(2)|endometrium(4)|large_intestine(1)|lung(4)|ovary(2)|prostate(2)	15		Colorectal(325;0.000257)|Breast(348;0.000278)|Lung NSC(340;0.000419)|Renal(390;0.000518)|all_lung(284;0.000567)|Ovarian(437;0.0221)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0182)|Colorectal(212;4.12e-07)|COAD - Colon adenocarcinoma(227;2.43e-05)|BRCA - Breast invasive adenocarcinoma(304;9.97e-05)|Kidney(64;0.000182)|KIRC - Kidney renal clear cell carcinoma(64;0.00269)|STAD - Stomach adenocarcinoma(313;0.012)|READ - Rectum adenocarcinoma(331;0.0649)		ACCTGCCCGGCAGGCCACGTG	0.657000														24			3		0	0	1	0	0
PNP	4860	broad.mit.edu	37	14	20944680	20944680	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr14:20944680G>A	uc001vxo.4	+	5	936	c.790G>A	c.(790-792)Ggc>Agc	p.G264S	PNP_uc021rns.1_Missense_Mutation_p.G135S	NM_000270	NP_000261	P00491	PNPH_HUMAN	Homo sapiens purine nucleoside phosphorylase (PNP), mRNA.	264					NAD biosynthesis via nicotinamide riboside salvage pathway|immune response|inosine catabolic process|interleukin-2 secretion|nicotinamide riboside catabolic process|positive regulation of T cell proliferation|positive regulation of alpha-beta T cell differentiation|purine base metabolic process|purine nucleotide catabolic process|purine-containing compound salvage|response to drug|urate biosynthetic process	cytoskeleton|cytosol	drug binding|nucleoside binding|phosphate binding|purine base binding|purine-nucleoside phosphorylase activity			cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(1)|ovary(2)|stomach(2)	10					Aciclovir(DB00787)|Cladribine(DB00242)|Mercaptopurine(DB01033)	CTTAGCAGCTGGCAAACAAGC	0.483000														51			49		0	0	1	0	0
NFIA	4774	broad.mit.edu	37	1	61869880	61869880	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr1:61869880G>A	uc010oos.2	+	8	1397	c.1315G>A	c.(1315-1317)Gag>Aag	p.E439K	NFIA_uc001czy.3_Missense_Mutation_p.E386K|NFIA_uc001czw.3_Missense_Mutation_p.E394K|NFIA_uc001czv.3_Missense_Mutation_p.E394K|NFIA_uc001czx.3_Missense_Mutation_p.E42K|NFIA_uc009wae.3_5'Flank	NM_001145512	NP_001138984	Q12857	NFIA_HUMAN	Homo sapiens nuclear factor I/A (NFIA), transcript variant 4, mRNA.	394					DNA replication|viral genome replication	cell junction|nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding	p.P439L(1)	NFIA/EHF(2)	endometrium(1)|kidney(2)|large_intestine(8)|lung(20)|pancreas(1)|prostate(1)|skin(1)	34						TCACCCTCAGGAGACGCTGAA	0.512000														103			8		0	0	1	0	0
RFX2	5990	broad.mit.edu	37	19	6004252	6004252	+	Missense_Mutation	SNP	T	C	C			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr19:6004252T>C	uc002meb.3	-	12	1729	c.1460A>G	c.(1459-1461)aAt>aGt	p.N487S	RFX2_uc002mec.3_Missense_Mutation_p.N462S	NM_000635	NP_000626	P48378	RFX2_HUMAN	Homo sapiens regulatory factor X, 2 (influences HLA class II expression) (RFX2), transcript variant 1, mRNA.	487					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding			breast(4)|central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(4)|ovary(1)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	21						ACTCATGGCATTTGTCAACCA	0.577000														103			4		0	0	1	0	0
CHPF2	54480	broad.mit.edu	37	7	150932432	150932432	+	Nonsense_Mutation	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr7:150932432C>T	uc003wjr.1	+	1	2075	c.562C>T	c.(562-564)Cag>Tag	p.Q188*	CHPF2_uc003wjq.1_Nonsense_Mutation_p.Q180*	NM_019015	NP_061888	Q9P2E5	CHPF2_HUMAN	Homo sapiens chondroitin polymerizing factor 2 (CHPF2), mRNA.	188						Golgi cisterna membrane|integral to membrane	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity			breast(1)|endometrium(2)|large_intestine(3)|lung(3)|ovary(4)|prostate(1)|skin(3)	17						CACATATGTGCAGGCCCCCCG	0.627000														49			31		0	0	1	0	0
USP3	9960	broad.mit.edu	37	15	63866525	63866525	+	Missense_Mutation	SNP	T	C	C			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr15:63866525T>C	uc002amf.3	+	10	1148	c.1019T>C	c.(1018-1020)cTt>cCt	p.L340P	USP3_uc010uii.1_Non-coding_Transcript|USP3_uc002amg.3_Missense_Mutation_p.L255P|USP3_uc002amh.3_Missense_Mutation_p.L318P|USP3_uc010uij.2_Missense_Mutation_p.L296P|USP3_uc010uik.2_Missense_Mutation_p.L91P|USP3_uc010bgs.3_Missense_Mutation_p.L323P|USP3_uc002ami.3_Missense_Mutation_p.L171P	NM_006537	NP_006528	Q9Y6I4	UBP3_HUMAN	Homo sapiens ubiquitin specific peptidase 3 (USP3), mRNA.	340					DNA repair|histone deubiquitination|mitotic cell cycle|regulation of protein stability|ubiquitin-dependent protein catabolic process	nuclear chromatin	histone binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|zinc ion binding			endometrium(3)|large_intestine(7)|lung(4)	14				GBM - Glioblastoma multiforme(80;0.0187)		TTTTAAGACCTTTCATTAGAT	0.338000														203			6		0	0	1	0	0
TMEM27	57393	broad.mit.edu	37	X	15657840	15657840	+	Silent	SNP	A	G	G			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chrX:15657840A>G	uc004cxc.2	-	4	613	c.357T>C	c.(355-357)aaT>aaC	p.N119N		NM_020665	NP_065716	Q9HBJ8	TMM27_HUMAN	Homo sapiens transmembrane protein 27 (TMEM27), mRNA.	119					proteolysis	integral to membrane	metallopeptidase activity|peptidyl-dipeptidase activity			endometrium(3)|lung(4)|ovary(1)	8	Hepatocellular(33;0.183)					GAGTTTGGTCATTTAGAAAGA	0.328000														3			117		0	0	1	0	0
PROP1	5626	broad.mit.edu	37	5	177421251	177421251	+	Silent	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr5:177421251C>T	uc003mif.1	-	1	507	c.198G>A	c.(196-198)ccG>ccA	p.P66P		NM_006261	NP_006252	O75360	PROP1_HUMAN	Homo sapiens PROP paired-like homeobox 1 (PROP1), mRNA.	66					central nervous system development	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity	p.P66P(4)		endometrium(1)|large_intestine(2)|lung(9)|stomach(1)	13	all_cancers(89;0.00176)|Renal(175;0.000269)|Lung NSC(126;0.00858)|all_lung(126;0.0139)	all_neural(177;0.00409)|Medulloblastoma(196;0.00498)|all_hematologic(541;0.21)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			GCCGGGAGTGCGGGCGGCCCC	0.662000														78			15		0	0	1	0	0
FREM2	341640	broad.mit.edu	37	13	39446906	39446906	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr13:39446906A>G	uc001uwv.3	+	16	8320	c.8011A>G	c.(8011-8013)Acc>Gcc	p.T2671A		NM_207361	NP_997244	Q5SZK8	FREM2_HUMAN	Homo sapiens FRAS1 related extracellular matrix protein 2 (FREM2), mRNA.	2671					cell communication|homophilic cell adhesion|multicellular organismal development	integral to membrane|plasma membrane	calcium ion binding			NS(1)|breast(2)|central_nervous_system(2)|cervix(1)|endometrium(14)|haematopoietic_and_lymphoid_tissue(3)|kidney(8)|large_intestine(35)|lung(39)|ovary(9)|pancreas(2)|prostate(12)|skin(11)|upper_aerodigestive_tract(7)|urinary_tract(2)	148		Lung NSC(96;1.04e-07)|Prostate(109;0.00384)|Breast(139;0.00396)|Lung SC(185;0.0565)|Hepatocellular(188;0.114)		all cancers(112;3.32e-07)|Epithelial(112;1.66e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.00154)|BRCA - Breast invasive adenocarcinoma(63;0.00631)|GBM - Glioblastoma multiforme(144;0.0312)		GTCCTATGTGACCCTTCGAGT	0.443000														141			5		0	0	1	0	0
C10orf120	399814	broad.mit.edu	37	10	124457698	124457698	+	Nonsense_Mutation	SNP	C	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr10:124457698C>A	uc001lgn.3	-	2	591	c.559G>T	c.(559-561)Gaa>Taa	p.E187*		NM_001010912	NP_001010912	Q5SQS8	CJ120_HUMAN	Homo sapiens chromosome 10 open reading frame 120 (C10orf120), mRNA.	187										endometrium(1)|kidney(1)|large_intestine(6)|lung(9)|skin(2)|stomach(1)|urinary_tract(1)	21		all_neural(114;0.169)|Glioma(114;0.222)				GTAAACCTTTCAATGTAGGGT	0.473000														99			15		0.00121646	0.00121646	1	1	0
ANP32A	8125	broad.mit.edu	37	15	69079816	69079816	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr15:69079816G>A	uc002arl.3	-	2	434	c.263C>T	c.(262-264)cCg>cTg	p.P88L		NM_006305	NP_006296	P39687	AN32A_HUMAN	Homo sapiens acidic (leucine-rich) nuclear phosphoprotein 32 family, member A (ANP32A), mRNA.	88					intracellular signal transduction|mRNA metabolic process|nucleocytoplasmic transport|regulation of transcription, DNA-dependent|transcription, DNA-dependent	endoplasmic reticulum|nucleoplasm|perinuclear region of cytoplasm	protein binding			endometrium(1)|large_intestine(1)|lung(2)	4						CGTGAGGTTCGGACACTTTTC	0.453000														114			13		0	0	1	0	0
ROBO2	6092	broad.mit.edu	37	3	77571941	77571941	+	Silent	SNP	C	T	T			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr3:77571941C>T	uc011bgk.2	+	5	1465	c.822C>T	c.(820-822)gaC>gaT	p.D274D	ROBO2_uc021xat.1_Silent_p.D290D|ROBO2_uc003dpy.4_Silent_p.D274D|ROBO2_uc003dpz.3_Silent_p.D274D|ROBO2_uc011bgj.2_Non-coding_Transcript	NM_002942	NP_002933	Q9HCK4	ROBO2_HUMAN	Homo sapiens roundabout, axon guidance receptor, homolog 2 (Drosophila) (ROBO2), transcript variant 2, mRNA.	274	Ig-like C2-type 3.				apoptosis involved in luteolysis|axon midline choice point recognition|cellular response to hormone stimulus|homophilic cell adhesion|metanephros development|negative regulation of negative chemotaxis|negative regulation of synaptogenesis|olfactory bulb interneuron development|positive regulation of axonogenesis|retinal ganglion cell axon guidance|ureteric bud development	axolemma|cell surface|integral to membrane	axon guidance receptor activity|identical protein binding			NS(1)|biliary_tract(5)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(23)|liver(1)|lung(52)|ovary(2)|pancreas(2)|prostate(5)|skin(8)|upper_aerodigestive_tract(1)	117				Epithelial(33;0.00199)|LUSC - Lung squamous cell carcinoma(21;0.008)|BRCA - Breast invasive adenocarcinoma(55;0.00884)|Lung(72;0.0183)|KIRC - Kidney renal clear cell carcinoma(39;0.0832)|Kidney(39;0.103)		ACATCAAAGACGATTACACAC	0.333000														101			4		0	0	1	0	0
CRYBG3	131544	broad.mit.edu	37	3	97596465	97596468	+	Frame_Shift_Del	DEL	AGAG	-	-			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr3:97596465_97596468delAGAG	uc003drx.3	+	0	647_650	c.583_586delAGAG	c.(583-588)agagagfs	p.R195fs	CRYBG3_uc021xbn.1_Frame_Shift_Del_p.R195fs					RecName: Full=Beta/gamma crystallin domain-containing protein 3;											breast(1)|cervix(1)|endometrium(5)|kidney(3)|large_intestine(9)|lung(10)|stomach(1)|upper_aerodigestive_tract(2)	32						TGAAGATGACAGAGAGGCAGCTGA	0.471													---	165	---	---	7	---					
PI4K2A	55361	broad.mit.edu	37	10	99400542	99400542	+	Frame_Shift_Del	DEL	C	-	-			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr10:99400542delC	uc001kog.1	+	0	100	c.43delC	c.(43-45)cccfs	p.P15fs	PI4K2A_uc010qoy.1_Intron	NM_018425	NP_060895	Q9BTU6	P4K2A_HUMAN	Homo sapiens phosphatidylinositol 4-kinase type 2 alpha (PI4K2A), mRNA.	15					phosphatidylinositol biosynthetic process	cytoplasm|integral to plasma membrane|membrane raft	1-phosphatidylinositol 4-kinase activity|ATP binding|magnesium ion binding			endometrium(2)|kidney(1)|large_intestine(3)|lung(3)|ovary(1)|prostate(1)|skin(1)	12		Colorectal(252;0.162)		Epithelial(162;1.24e-10)|all cancers(201;1.2e-08)		GCGGGCCCAACCCCCGGACTA	0.766													---	4	---	---	2	---					
E2F7	144455	broad.mit.edu	37	12	77419489	77419490	+	Frame_Shift_Del	DEL	TT	-	-			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr12:77419489_77419490delTT	uc001sym.4	-	11	2649_2650	c.2413_2414delAA	c.(2413-2415)aagfs	p.K805fs	E2F7_uc009zse.3_Intron	NM_203394	NP_976328	Q96AV8	E2F7_HUMAN	Homo sapiens E2F transcription factor 7 (E2F7), mRNA.	805					cell cycle	transcription factor complex	DNA binding|identical protein binding			central_nervous_system(1)|endometrium(3)|kidney(4)|large_intestine(15)|lung(14)|ovary(3)|upper_aerodigestive_tract(2)	42						TGTGGACGACTTTGGATTAACC	0.530													---	123	---	---	9	---					
TPT1-AS1	100190939	broad.mit.edu	37	13	45963872	45963875	+	RNA	DEL	AAAC	-	-			TCGA-KL-8328-01A-11D-2310-10	TCGA-KL-8328-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ccd028d-e7e0-4f77-a512-f658a31819a4	f468e484-9121-46a5-90cf-abe4cf4e7335	g.chr13:45963872_45963875delAAAC	uc010tfr.2	+	9		c.989_992delAAAC			TPT1-AS1_uc001vac.3_Non-coding_Transcript|TPT1-AS1_uc021rjh.1_Non-coding_Transcript					Homo sapiens uncharacterized LOC100190939 (LOC100190939), non-coding RNA.																		TTTAATAGAAAAACAAACAAAGAC	0.324													---	201	---	---	14	---					
