Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
DMD	1756	broad.mit.edu	37	X	32408279	32408279	+	Missense_Mutation	SNP	G	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chrX:32408279G>T	uc004dda.1	-	30	4497	c.4253C>A	c.(4252-4254)aCa>aAa	p.T1418K	DMD_uc004dcw.2_Missense_Mutation_p.T74K|DMD_uc004dcx.2_Missense_Mutation_p.T77K|DMD_uc004dcz.2_Missense_Mutation_p.T1295K|DMD_uc004dcy.1_Missense_Mutation_p.T1414K|DMD_uc004ddb.1_Missense_Mutation_p.T1410K|DMD_uc010ngo.1_Intron	NM_004006	NP_004001	P11532	DMD_HUMAN	Homo sapiens dystrophin (DMD), transcript variant Dp427m, mRNA.	1418	Interaction with SYNM (By similarity).				muscle filament sliding|peptide biosynthetic process	cell surface|costamere|cytoskeleton|cytosol|dystrophin-associated glycoprotein complex|sarcolemma	actin binding|dystroglycan binding|nitric-oxide synthase binding|protein binding|structural constituent of cytoskeleton|structural constituent of muscle|zinc ion binding	p.T1414R(1)|p.T77R(1)|p.T1418R(1)|p.T1413R(1)		NS(2)|breast(3)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(17)|liver(1)|lung(25)|ovary(3)|pancreas(3)|prostate(2)|skin(1)|urinary_tract(2)	77		all_cancers(2;1.22e-16)|Acute lymphoblastic leukemia(2;4.65e-06)|all_hematologic(2;0.00108)|all_epithelial(3;0.00626)|all_neural(2;0.0189)|all_lung(315;0.182)|Glioma(3;0.203)				CTCATGACTTGTCAAATCAGA	0.388000														9			121		9.48018e-61	1.09387e-60	1	1	0
LILRP2	79166	broad.mit.edu	37	19	55221850	55221850	+	RNA	SNP	G	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr19:55221850G>A	uc002qgs.1	+	0		c.2250G>A			LILRP2_uc002qgt.1_Intron					Homo sapiens leukocyte immunoglobulin-like receptor pseudogene 2 (LILRP2), non-coding RNA.																		AGCTCAGAACGAGGTGGGGCA	0.637000														46			3		0	0	1	0	0
MMP3	4314	broad.mit.edu	37	11	102709283	102709283	+	Splice_Site	SNP	T	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr11:102709283T>G	uc001phj.1	-	8	1294	c.1229_splice	c.e8+1	p.R410_splice	DD413629_uc021qpi.1_5'Flank	NM_002422	NP_002413	P08254	MMP3_HUMAN	Homo sapiens matrix metallopeptidase 3 (stromelysin 1, progelatinase) (MMP3), mRNA.	410	Hemopexin-like 3.				collagen catabolic process|proteolysis	extracellular space|proteinaceous extracellular matrix	calcium ion binding|metalloendopeptidase activity|zinc ion binding			endometrium(2)|kidney(3)|large_intestine(3)|liver(1)|lung(7)|ovary(2)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	22		all_hematologic(158;0.00092)|Acute lymphoblastic leukemia(157;0.000967)		BRCA - Breast invasive adenocarcinoma(274;0.0142)	Marimastat(DB00786)|Simvastatin(DB00641)	GCATCTCACCTCCAGTATTTG	0.423000														138			15		0	0	1	0	0
MTM1	4534	broad.mit.edu	37	X	149764981	149764981	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chrX:149764981A>G	uc004fef.4	+	2	159	c.83A>G	c.(82-84)aAt>aGt	p.N28S	MTM1_uc011mxx.2_Non-coding_Transcript|MTM1_uc011mxy.2_Missense_Mutation_p.N28S|MTM1_uc011mxz.2_5'UTR|MTM1_uc010nte.3_5'UTR	NM_000252	NP_000243	Q13496	MTM1_HUMAN	Homo sapiens myotubularin 1 (MTM1), mRNA.	28					endosome to lysosome transport|intermediate filament organization|mitochondrion distribution|mitochondrion morphogenesis|phosphatidylinositol dephosphorylation|protein transport|regulation of vacuole organization	filopodium|late endosome|plasma membrane|ruffle	intermediate filament binding|phosphatidylinositol binding|phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity|phosphatidylinositol-3-phosphatase activity|protein tyrosine phosphatase activity			breast(2)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(4)|liver(1)|lung(10)|ovary(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	26	Acute lymphoblastic leukemia(192;6.56e-05)					GATGGAGTCAATCGAGATCTC	0.418000														42			6		0	0	1	0	0
MYO5C	55930	broad.mit.edu	37	15	52562050	52562050	+	Silent	SNP	G	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr15:52562050G>A	uc010bff.3	-	7	1002	c.840C>T	c.(838-840)gcC>gcT	p.A280A	MYO5C_uc010uga.2_Non-coding_Transcript|MYO5C_uc010ugb.2_Non-coding_Transcript|MYO5C_uc010ugc.2_Intron	NM_018728	NP_061198	Q9NQX4	MYO5C_HUMAN	Homo sapiens myosin VC (MYO5C), mRNA.	280	Myosin head-like.					myosin complex	ATP binding|actin binding|calmodulin binding|motor activity			breast(1)|central_nervous_system(3)|cervix(1)|endometrium(8)|kidney(7)|large_intestine(15)|lung(12)|ovary(7)|prostate(3)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	66				all cancers(107;0.0137)		TAAATTCTTCGGCACTCCCTG	0.378000														71			18		0	0	1	0	0
F379	0	broad.mit.edu	37	12	68787	68787	+	RNA	SNP	G	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr12:68787G>A	uc010scw.1	+	2		c.832G>A								Homo sapiens chromosome 6 F379 retina specific protein (F379) mRNA, complete cds.																		ctcctgggtagacagccagac	0.557000														55			7		0	0	1	0	0
NOTCH2	4853	broad.mit.edu	37	1	120462211	120462211	+	Silent	SNP	A	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr1:120462211A>G	uc001eik.3	-	30	5802	c.5505T>C	c.(5503-5505)gcT>gcC	p.A1835A		NM_024408	NP_077719	Q04721	NOTC2_HUMAN	Homo sapiens notch 2 (NOTCH2), transcript variant 1, mRNA.	1835					Notch receptor processing|Notch signaling pathway|anti-apoptosis|bone remodeling|cell cycle arrest|cell fate determination|cell growth|hemopoiesis|induction of apoptosis|negative regulation of cell proliferation|nervous system development|organ morphogenesis|positive regulation of Ras protein signal transduction|regulation of transcription, DNA-dependent|stem cell maintenance|transcription, DNA-dependent	Golgi lumen|cell surface|cytosol|endoplasmic reticulum lumen|extracellular region|integral to plasma membrane|nucleoplasm	calcium ion binding|ligand-regulated transcription factor activity|protein binding|receptor activity			breast(4)|central_nervous_system(6)|cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(9)|kidney(9)|large_intestine(19)|liver(1)|lung(57)|ovary(4)|pancreas(1)|prostate(7)|skin(24)|stomach(2)|upper_aerodigestive_tract(5)|urinary_tract(1)	158	all_neural(166;0.153)	all_lung(203;1.96e-06)|Lung NSC(69;1.47e-05)|all_epithelial(167;0.000809)		Lung(183;0.0242)|LUSC - Lung squamous cell carcinoma(189;0.133)		CTCGGAGAGAAGCCAACATCA	0.463000			"""N, F, Mis"""		"""marginal zone lymphoma, DLBCL"""				Alagille Syndrome					60			4		0	0	1	0	0
ZCCHC6	79670	broad.mit.edu	37	9	88937294	88937294	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr9:88937294G>A	uc004aou.3	-	13	3112	c.2974C>T	c.(2974-2976)Cca>Tca	p.P992S	ZCCHC6_uc010mqe.3_5'Flank|ZCCHC6_uc011ltf.2_Non-coding_Transcript|ZCCHC6_uc004aoq.3_Missense_Mutation_p.P992S|ZCCHC6_uc004aot.3_Intron|ZCCHC6_uc004aor.3_Non-coding_Transcript|ZCCHC6_uc004aos.3_Non-coding_Transcript	NM_001185059	NP_078893	Q5VYS8	TUT7_HUMAN	Homo sapiens zinc finger, CCHC domain containing 6 (ZCCHC6), transcript variant 2, mRNA.	992					RNA 3'-end processing		RNA uridylyltransferase activity|nucleic acid binding|zinc ion binding			breast(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(10)|liver(1)|lung(14)|ovary(2)|prostate(1)|skin(2)|urinary_tract(1)	46						GGTGTTAATGGTGGCAGAGGT	0.373000														81			64		0	0	1	0	0
SCG2	7857	broad.mit.edu	37	2	224462648	224462648	+	Silent	SNP	C	T	T	rs143843249	byFrequency	TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr2:224462648C>T	uc021vxk.1	-	0	1353	c.1353G>A	c.(1351-1353)tcG>tcA	p.S451S	SCG2_uc002vnm.3_Silent_p.S451S	NM_003469	NP_003460	P13521	SCG2_HUMAN	Homo sapiens secretogranin II (SCG2), mRNA.	451					MAPKKK cascade|angiogenesis|endothelial cell migration|eosinophil chemotaxis|induction of positive chemotaxis|inflammatory response|negative regulation of apoptosis|negative regulation of endothelial cell proliferation|positive regulation of endothelial cell proliferation|protein secretion	extracellular space|stored secretory granule	chemoattractant activity|cytokine activity	p.T450T(1)		NS(1)|breast(1)|endometrium(1)|kidney(6)|large_intestine(10)|liver(1)|lung(16)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(4)	44		Renal(207;0.0112)|Lung NSC(271;0.0185)|all_lung(227;0.0271)		Epithelial(121;8.16e-11)|all cancers(144;4.66e-08)|Lung(261;0.00714)|LUSC - Lung squamous cell carcinoma(224;0.008)		TGGGAAAATACGACGTTTTCT	0.488000														32			28		0	0	1	0	0
PLK3	1263	broad.mit.edu	37	1	45270133	45270133	+	Missense_Mutation	SNP	T	C	C			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr1:45270133T>C	uc001cmn.3	+	11	1565	c.1465T>C	c.(1465-1467)Ttc>Ctc	p.F489L		NM_004073	NP_004064	Q9H4B4	PLK3_HUMAN	Homo sapiens polo-like kinase 3 (PLK3), mRNA.	489	POLO box 1.					membrane	ATP binding|protein binding|protein serine/threonine kinase activity			endometrium(4)|large_intestine(2)|lung(8)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	19	Acute lymphoblastic leukemia(166;0.155)					GGCTGTGCTCTTCAACGATGG	0.567000														94			4		0	0	1	0	0
ZNF445	353274	broad.mit.edu	37	3	44488434	44488434	+	Missense_Mutation	SNP	G	C	C			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr3:44488434G>C	uc003cnf.2	-	7	3077	c.2729C>G	c.(2728-2730)aCc>aGc	p.T910S	ZNF445_uc011azv.1_Missense_Mutation_p.T898S|ZNF445_uc011azw.1_Missense_Mutation_p.T910S	NM_181489	NP_852466	P59923	ZN445_HUMAN	Homo sapiens zinc finger protein 445 (ZNF445), mRNA.	910					viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|endometrium(5)|kidney(3)|large_intestine(8)|lung(8)|ovary(2)|pancreas(1)|skin(3)	31				KIRC - Kidney renal clear cell carcinoma(197;0.0514)|Kidney(197;0.0646)		ACTGGAAAGGGTATGTCTCCC	0.483000														81			66		0	0	1	0	0
LARP7	51574	broad.mit.edu	37	4	113568911	113568911	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr4:113568911A>G	uc003iaz.3	+	9	1549	c.1084A>G	c.(1084-1086)Aca>Gca	p.T362A	LARP7_uc003iay.3_Missense_Mutation_p.T355A|LARP7_uc003iba.3_Missense_Mutation_p.T276A|LARP7_uc003ibb.3_Missense_Mutation_p.T355A	NM_016648	NP_057732	Q4G0J3	LARP7_HUMAN	Homo sapiens La ribonucleoprotein domain family, member 7 (LARP7), transcript variant 1, mRNA.	355	Lys-rich.				RNA processing	nucleoplasm|ribonucleoprotein complex	RNA binding|nucleotide binding			endometrium(2)|large_intestine(2)|lung(8)|ovary(4)|skin(1)	17		Ovarian(17;0.0443)|Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;0.000603)		TCTCTTGAAAACAAAAAGGAA	0.308000														147			5		0	0	1	0	0
NECAB2	54550	broad.mit.edu	37	16	84024120	84024120	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr16:84024120G>A	uc002fhd.3	+	5	498	c.481G>A	c.(481-483)Gtg>Atg	p.V161M	NECAB2_uc002fhe.3_Missense_Mutation_p.V78M	NM_019065	NP_061938	Q7Z6G3	NECA2_HUMAN	Homo sapiens N-terminal EF-hand calcium binding protein 2 (NECAB2), mRNA.	161					antibiotic biosynthetic process	cytoplasm	calcium ion binding|oxidoreductase activity|protein binding			endometrium(1)|large_intestine(3)|lung(9)|ovary(2)|prostate(1)|stomach(2)|urinary_tract(1)	19						TGGGAGCAACGTGGACCAGTT	0.582000														84			4		0	0	1	0	0
DST	667	broad.mit.edu	37	6	56417258	56417258	+	Missense_Mutation	SNP	T	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr6:56417258T>A	uc003pcy.4	-	41	8571	c.8463A>T	c.(8461-8463)aaA>aaT	p.K2821N		NM_015548	NP_056363	Q03001	DYST_HUMAN	Homo sapiens dystonin (DST), transcript variant 1eA, mRNA.	5233					cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	Z disc|actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein C-terminus binding|protein binding|protein homodimerization activity			NS(1)|breast(5)|central_nervous_system(8)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(22)|lung(43)|ovary(7)|prostate(1)|skin(4)|upper_aerodigestive_tract(3)	105	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			TCTTGCAGGTTTTATTGGCAT	0.418000														106			24		0	0	1	0	0
KIAA1704	55425	broad.mit.edu	37	13	45582989	45582989	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr13:45582989A>G	uc001uzq.3	+	3	486	c.383A>G	c.(382-384)aAg>aGg	p.K128R	KIAA1704_uc010tfo.1_Non-coding_Transcript|KIAA1704_uc001uzr.1_Missense_Mutation_p.K128R|KIAA1704_uc001uzs.3_5'UTR|KIAA1704_uc001uzt.3_5'UTR	NM_018559	NP_061029	Q8IXQ4	K1704_HUMAN	Homo sapiens KIAA1704 (KIAA1704), mRNA.	128										breast(1)|endometrium(1)|kidney(2)|large_intestine(3)|lung(1)|pancreas(1)|prostate(2)|skin(1)	12		Lung NSC(96;0.00143)|Prostate(109;0.0137)|Breast(139;0.0192)|Lung SC(185;0.0367)|Hepatocellular(98;0.133)	KIRC - Kidney renal clear cell carcinoma(16;0.234)	GBM - Glioblastoma multiforme(144;0.000313)|BRCA - Breast invasive adenocarcinoma(63;0.126)		AAAAGTGACAAGGGCAGAGAT	0.368000														89			4		0	0	1	0	0
UGT2B7	7364	broad.mit.edu	37	4	69978239	69978239	+	Nonsense_Mutation	SNP	C	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr4:69978239C>T	uc003heg.4	+	5	1421	c.1375C>T	c.(1375-1377)Cga>Tga	p.R459*	UGT2B7_uc010ihq.3_3'UTR	NM_001074	NP_001065	P16662	UD2B7_HUMAN	Homo sapiens UDP glucuronosyltransferase 2 family, polypeptide B7 (UGT2B7), mRNA.	459					lipid metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	glucuronosyltransferase activity	p.R459L(1)		autonomic_ganglia(1)|endometrium(3)|kidney(4)|large_intestine(6)|lung(16)|ovary(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	38						GCCCCTGGATCGAGCAGTCTT	0.423000														58			56		0	0	1	0	0
ATP6V1B1	525	broad.mit.edu	37	2	71192114	71192114	+	Missense_Mutation	SNP	G	A	A	rs140980255		TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr2:71192114G>A	uc002shj.3	+	13	1492	c.1405G>A	c.(1405-1407)Gag>Aag	p.E469K	ATP6V1B1_uc010fdx.3_Missense_Mutation_p.E427K	NM_001692	NP_001683	P15313	VATB1_HUMAN	Homo sapiens ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (ATP6V1B1), mRNA.	469					ATP hydrolysis coupled proton transport|calcium ion homeostasis|cellular iron ion homeostasis|excretion|inner ear morphogenesis|insulin receptor signaling pathway|ossification|pH reduction|sensory perception of sound|transferrin transport	apical plasma membrane|basolateral plasma membrane|cytosol|endomembrane system|lateral plasma membrane|microvillus|proton-transporting V-type ATPase, V1 domain|vacuolar proton-transporting V-type ATPase complex	ATP binding|hydrogen ion transporting ATP synthase activity, rotational mechanism|proton-transporting ATPase activity, rotational mechanism			endometrium(5)|kidney(1)|large_intestine(5)|liver(1)|lung(5)|prostate(1)|skin(1)	19						CTCGGTGTTCGAGTCGCTGGA	0.617000											OREG0014686	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		9			43		0	0	1	0	0
DOCK4	9732	broad.mit.edu	37	7	111368593	111368593	+	Missense_Mutation	SNP	C	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr7:111368593C>G	uc003vfy.3	-	53	6042	c.5773G>C	c.(5773-5775)Gtg>Ctg	p.V1925L	DOCK4_uc011kml.2_Missense_Mutation_p.V761L|DOCK4_uc011kmm.2_Missense_Mutation_p.V749L|DOCK4_uc003vfw.3_Missense_Mutation_p.V1292L|DOCK4_uc003vfx.3_Missense_Mutation_p.V1880L|DOCK4_uc003vfv.3_Missense_Mutation_p.V193L	NM_014705	NP_055520	Q8N1I0	DOCK4_HUMAN	Homo sapiens dedicator of cytokinesis 4 (DOCK4), mRNA.	1880	Pro-rich.				cell chemotaxis	cytosol|endomembrane system|membrane|stereocilium	GTP binding|PDZ domain binding|Rac GTPase activator activity|Rac GTPase binding|SH3 domain binding|guanyl-nucleotide exchange factor activity|receptor tyrosine kinase binding			NS(1)|breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(4)|kidney(4)|large_intestine(13)|lung(31)|ovary(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(4)	72		Acute lymphoblastic leukemia(1;0.0441)				GGCACCGGCACTGGCACCGGC	0.647000														18			3		0	0	1	0	0
UNC80	285175	broad.mit.edu	37	2	210683986	210683986	+	Splice_Site	SNP	G	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr2:210683986G>T	uc010zjc.1	+	12	2042	c.1962_splice	c.e12+1	p.S654_splice	UNC80_uc021vvx.1_Splice_Site_p.S654_splice	NM_032504	NP_115893	Q8N2C7	UNC80_HUMAN	Homo sapiens unc-80 homolog (C. elegans) (UNC80), transcript variant 1, mRNA.	654						integral to membrane				breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|lung(9)|ovary(1)|prostate(1)	20						TGATCTTTCTGTAAGAAGCAA	0.343000														18			12		2.80697e-09	2.90377e-09	1	1	0
AGPAT9	84803	broad.mit.edu	37	4	84518658	84518658	+	Missense_Mutation	SNP	T	C	C			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr4:84518658T>C	uc003how.3	+	9	1204	c.986T>C	c.(985-987)gTt>gCt	p.V329A	AGPAT9_uc003hox.3_Missense_Mutation_p.V329A|AGPAT9_uc003hoy.3_Missense_Mutation_p.V329A	NM_032717	NP_116106	Q53EU6	GPAT3_HUMAN	Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9), transcript variant 1, mRNA.	329					phospholipid biosynthetic process|regulation of TOR signaling cascade|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane	glycerol-3-phosphate O-acyltransferase activity			endometrium(1)|kidney(1)|large_intestine(4)|lung(4)|skin(3)	13		Hepatocellular(203;0.114)				ATACATCCAGTTGCAATTAAG	0.333000														175			5		0	0	1	0	0
ZNF415	55786	broad.mit.edu	37	19	53619570	53619570	+	Missense_Mutation	SNP	G	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr19:53619570G>T	uc002qax.3	-	3	419	c.70C>A	c.(70-72)Cct>Act	p.P24T	ZNF415_uc010yds.2_Silent_p.S44S|ZNF415_uc010ydt.2_Silent_p.S44S|ZNF415_uc002qau.3_5'UTR|ZNF415_uc002qav.3_Missense_Mutation_p.P24T|ZNF415_uc002qaw.3_Silent_p.S44S|ZNF415_uc002qay.3_5'UTR|ZNF415_uc002qaz.3_Missense_Mutation_p.P24T|ZNF415_uc002qba.3_Intron			Q09FC8	ZN415_HUMAN	Homo sapiens zinc finger protein 415 (ZNF415), transcript variant 4, non-coding RNA.	24					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|microtubule cytoskeleton|nucleolus	DNA binding|zinc ion binding			breast(1)|kidney(3)|large_intestine(8)|lung(11)|ovary(2)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	31				GBM - Glioblastoma multiforme(134;0.0191)		CCTCACCCAGGGAGACCAGGT	0.468000														63			4		0.00024832	0.00024832	1	1	0
C1orf52	148423	broad.mit.edu	37	1	85718363	85718363	+	Silent	SNP	A	G	G	rs111657378		TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr1:85718363A>G	uc001dkv.3	-	2	537	c.498T>C	c.(496-498)acT>acC	p.T166T	C1orf52_uc001dkw.3_Non-coding_Transcript	NM_198077	NP_932343	Q8N6N3	CA052_HUMAN	Homo sapiens chromosome 1 open reading frame 52 (C1orf52), transcript variant 1, mRNA.	166										endometrium(1)|kidney(1)|large_intestine(4)|lung(3)|ovary(1)	10				all cancers(265;0.0105)|Epithelial(280;0.0293)		GCTTTTTAGAAGTATGCTCAT	0.318000														125			4		0	0	1	0	0
TONSL	4796	broad.mit.edu	37	8	145661996	145661996	+	Silent	SNP	C	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr8:145661996C>T	uc011llg.2	-	15	1974	c.1959G>A	c.(1957-1959)acG>acA	p.T653T	AK298596_uc011llh.1_Intron	NM_013432	NP_038460	Q96HA7	TONSL_HUMAN	Homo sapiens tonsoku-like, DNA repair protein (TONSL), mRNA.	653					cytoplasmic sequestering of transcription factor|double-strand break repair via homologous recombination|replication fork processing	cytoplasm|nuclear replication fork	histone binding|transcription corepressor activity			biliary_tract(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(2)|lung(14)|ovary(3)|prostate(1)|skin(1)	26						CCTTCTGCCGCGTCTCCAGGT	0.672000														86			7		0	0	1	0	0
MIB1	57534	broad.mit.edu	37	18	19379923	19379923	+	Silent	SNP	A	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr18:19379923A>G	uc002ktq.3	+	8	1359	c.1359A>G	c.(1357-1359)agA>agG	p.R453R	MIB1_uc002ktp.3_Silent_p.R92R	NM_020774	NP_065825	Q86YT6	MIB1_HUMAN	Homo sapiens mindbomb homolog 1 (Drosophila) (MIB1), mRNA.	453					Notch signaling pathway	centrosome|nuclear membrane|plasma membrane	ubiquitin-protein ligase activity|zinc ion binding			breast(1)|endometrium(2)|kidney(2)|large_intestine(4)|lung(13)|ovary(5)	27			STAD - Stomach adenocarcinoma(5;0.212)			TGCTTAAAAGACCAGATGTGG	0.333000														82			4		0	0	1	0	0
RUFY3	22902	broad.mit.edu	37	4	71588442	71588442	+	Missense_Mutation	SNP	C	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr4:71588442C>A	uc003hfr.3	+	0	747	c.152C>A	c.(151-153)aCa>aAa	p.T51K	RUFY3_uc003hfp.4_Intron|RUFY3_uc003hfq.3_Missense_Mutation_p.T51K|RUFY3_uc011cax.2_Missense_Mutation_p.T51K	NM_001037442	NP_001032519	Q7L099	RUFY3_HUMAN	Homo sapiens RUN and FYVE domain containing 3 (RUFY3), transcript variant 1, mRNA.	51					negative regulation of axonogenesis	filopodium|growth cone		p.L50F(1)		endometrium(1)|kidney(3)|large_intestine(4)|lung(6)|prostate(1)|stomach(1)	16		all_hematologic(202;0.248)	Lung(101;0.235)			ATCTCACTTACACCTGACCCA	0.532000														87			16		2.48551e-13	2.66304e-13	1	1	0
PPM1G	5496	broad.mit.edu	37	2	27607890	27607890	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr2:27607890G>A	uc002rkl.3	-	4	682	c.475C>T	c.(475-477)Cgc>Tgc	p.R159C	PPM1G_uc002rkm.3_Missense_Mutation_p.R9C	NM_177983	NP_817092	O15355	PPM1G_HUMAN	Homo sapiens protein phosphatase, Mg2+/Mn2+ dependent, 1G (PPM1G), mRNA.	159					cell cycle arrest|protein dephosphorylation	cytoplasm|nucleus|protein serine/threonine phosphatase complex	metal ion binding|protein serine/threonine phosphatase activity			endometrium(2)|kidney(1)|large_intestine(2)|lung(9)|ovary(1)|prostate(2)|urinary_tract(2)	19	Acute lymphoblastic leukemia(172;0.155)					TGCCCGTAGCGTGTCAGCAGC	0.597000														2			20		0	0	1	0	0
SLCO4A1	28231	broad.mit.edu	37	20	61292501	61292501	+	Missense_Mutation	SNP	T	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr20:61292501T>G	uc002ydb.1	+	4	1300	c.1095T>G	c.(1093-1095)ttT>ttG	p.F365L		NM_016354	NP_057438	Q96BD0	SO4A1_HUMAN	Homo sapiens solute carrier organic anion transporter family, member 4A1 (SLCO4A1), mRNA.	365					sodium-independent organic anion transport	integral to membrane|plasma membrane	thyroid hormone transmembrane transporter activity			endometrium(6)|kidney(2)|large_intestine(1)|lung(7)|ovary(3)|prostate(2)	21	Breast(26;3.65e-08)		BRCA - Breast invasive adenocarcinoma(19;2.33e-06)			ACCCGGACTTTGGGAAAACCA	0.597000														26			4		0	0	1	0	0
PCDHGC5	56097	broad.mit.edu	37	5	140857474	140857474	+	Silent	SNP	C	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr5:140857474C>T	uc003lkv.2	+	0	1906	c.1791C>T	c.(1789-1791)gaC>gaT	p.D597D	PCDHGC5_uc003lji.2_Intron|PCDHGC5_uc003ljk.2_Intron|PCDHGC5_uc003ljm.2_Intron|PCDHGC5_uc003ljo.2_Intron|PCDHGC5_uc003ljq.2_Intron|PCDHGC5_uc003ljs.2_Intron|PCDHGC5_uc003lju.2_Intron|PCDHGC5_uc003ljw.2_Intron|PCDHGC5_uc003ljy.2_Intron|PCDHGC5_uc003lka.2_Intron|PCDHGC5_uc003lkc.2_Intron|PCDHGC5_uc003lkd.2_Intron|PCDHGC5_uc003lkf.2_Intron|PCDHGC5_uc003lkh.2_Intron|PCDHGC5_uc003lkj.2_Intron|PCDHGC5_uc003lkl.2_Intron|PCDHGC5_uc003lkn.2_Intron|PCDHGC5_uc003lkq.2_Intron|PCDHGC5_uc003lkp.2_Intron|PCDHGC5_uc003lkt.2_Intron|PCDHGC5_uc003lku.1_Silent_p.D597D|PCDHGC5_uc003lkw.2_Intron	NM_002588	NP_002579	Q9Y5F6	PCDGM_HUMAN	Homo sapiens protocadherin gamma subfamily C, 3 (PCDHGC3), transcript variant 1, mRNA.	596	Cadherin 6.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			breast(2)|central_nervous_system(2)|endometrium(6)|kidney(4)|large_intestine(4)|lung(10)|ovary(4)|prostate(1)|urinary_tract(2)	35			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			TAGGCTGGGACGCGGATGCAG	0.602000											OREG0016865	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		28			14		0	0	1	0	0
KCNJ8	3764	broad.mit.edu	37	12	21918737	21918737	+	Silent	SNP	G	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr12:21918737G>T	uc001rff.3	-	2	1533	c.1195C>A	c.(1195-1197)Cga>Aga	p.R399R		NM_004982	NP_004973	Q15842	IRK8_HUMAN	Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 8 (KCNJ8), mRNA.	399						voltage-gated potassium channel complex		p.R399*(2)		cervix(1)|endometrium(1)|kidney(2)|large_intestine(6)|lung(10)|ovary(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(1)	28					Levosimendan(DB00922)	TTGTTCCTTCGGATAGAATTG	0.418000														282			46		6.34439e-16	7.04932e-16	1	1	0
MGC70870	403340	broad.mit.edu	37	GL000205.1	117684	117684	+	RNA	SNP	C	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chrGL000205.1:117684C>T	uc002kgk.4	+	0		c.1062C>T								Homo sapiens C-terminal binding protein 2 pseudogene (MGC70870), non-coding RNA.																		AGCAGATTGGCGAGGTGGCCT	0.602000														11			4		0	0	1	0	0
RBM47	54502	broad.mit.edu	37	4	40438607	40438608	+	Frame_Shift_Ins	INS	-	T	T			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr4:40438607_40438608insT	uc003gvc.2	-	4	1890_1891	c.1180_1181insA	c.(1180-1182)aggfs	p.R394fs	RBM47_uc003gvd.2_Intron|RBM47_uc003gve.2_Non-coding_Transcript|RBM47_uc011bys.1_Frame_Shift_Ins_p.R356fs	NM_001098634	NP_001092104	A0AV96	RBM47_HUMAN	Homo sapiens RNA binding motif protein 47 (RBM47), transcript variant 1, mRNA.	394						nucleus	RNA binding|nucleotide binding			breast(5)|endometrium(1)|kidney(3)|large_intestine(2)|lung(9)|ovary(1)|prostate(3)|skin(4)|upper_aerodigestive_tract(1)	29						GTAGGAACCCCTAGGCCCTGGG	0.515													---	97	---	---	35	---					
CHMP4C	92421	broad.mit.edu	37	8	82644910	82644911	+	Frame_Shift_Ins	INS	-	G	G			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr8:82644910_82644911insG	uc003ycl.3	+	0	223_224	c.49_50insG	c.(49-51)cgafs	p.R17fs		NM_152284	NP_689497	Q96CF2	CHM4C_HUMAN	Homo sapiens charged multivesicular body protein 4C (CHMP4C), mRNA.	17	Intramolecular interaction with C- terminus (By similarity).				cellular membrane organization|endosome transport|protein transport	cytosol|late endosome membrane	protein binding			NS(1)|breast(2)|endometrium(2)|large_intestine(1)|lung(1)|ovary(2)|skin(1)	10						TTCTAAGAGCCGAGCCGCTCCC	0.599													---	106	---	---	7	---					
DOCK8	81704	broad.mit.edu	37	9	405015	405015	+	Frame_Shift_Del	DEL	T	-	-			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr9:405015delT	uc003zgf.2	+	26	3444	c.3332delT	c.(3331-3333)cttfs	p.L1111fs	DOCK8_uc022bcu.1_Frame_Shift_Del_p.L1043fs|DOCK8_uc010mgv.3_Frame_Shift_Del_p.L1011fs|DOCK8_uc010mgu.3_Frame_Shift_Del_p.L413fs|DOCK8_uc010mgw.2_Frame_Shift_Del_p.L413fs|DOCK8_uc003zgk.2_Frame_Shift_Del_p.L569fs	NM_203447	NP_001180465	Q8NF50	DOCK8_HUMAN	Homo sapiens dedicator of cytokinesis 8 (DOCK8), transcript variant 1, mRNA.	1111					blood coagulation	cytosol	GTP binding|GTPase binding|guanyl-nucleotide exchange factor activity			breast(1)|central_nervous_system(5)|endometrium(2)|kidney(6)|large_intestine(13)|lung(22)|ovary(3)|prostate(3)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(6)	65		all_cancers(5;2.13e-17)|all_epithelial(5;2.15e-12)|all_lung(10;6.69e-11)|Lung NSC(10;1.08e-10)|Acute lymphoblastic leukemia(5;0.000242)|all_hematologic(5;0.00317)|Breast(48;0.0151)|Prostate(43;0.128)		all cancers(5;9.3e-07)|GBM - Glioblastoma multiforme(5;2.41e-06)|Epithelial(6;0.00557)|Lung(218;0.00942)		AATCTGAACCTTTTTTTTATG	0.393													---	157	---	---	7	---					
CDHR5	53841	broad.mit.edu	37	11	618824	618824	+	Frame_Shift_Del	DEL	A	-	-			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr11:618824delA	uc001lql.3	-	12	2002	c.1735delT	c.(1735-1737)tctfs	p.S579fs	IRF7_uc001lqh.3_5'Flank|IRF7_uc001lqi.3_5'Flank|IRF7_uc010qwh.2_5'Flank|CDHR5_uc001lqj.3_Frame_Shift_Del_p.S579fs|CDHR5_uc009ycd.3_Frame_Shift_Del_p.S573fs|CDHR5_uc001lqk.3_Intron|CDHR5_uc009ycc.3_Frame_Shift_Del_p.S413fs	NM_021924	NP_068743	Q9HBB8	CDHR5_HUMAN	Homo sapiens cadherin-related family member 5 (CDHR5), transcript variant 1, mRNA.	579	4 X 31 AA approximate tandem repeats.				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			NS(1)|breast(1)|endometrium(4)|kidney(1)|large_intestine(6)|lung(7)|ovary(1)|skin(2)	23						ATCGGCTGAGAGGTTCCTGGC	0.667													---	142	---	---	8	---					
CDHR5	53841	broad.mit.edu	37	11	618827	618827	+	Frame_Shift_Del	DEL	T	-	-			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr11:618827delT	uc001lql.3	-	12	1999	c.1732delA	c.(1732-1734)accfs	p.T578fs	IRF7_uc001lqh.3_5'Flank|IRF7_uc001lqi.3_5'Flank|IRF7_uc010qwh.2_5'Flank|CDHR5_uc001lqj.3_Frame_Shift_Del_p.T578fs|CDHR5_uc009ycd.3_Frame_Shift_Del_p.T572fs|CDHR5_uc001lqk.3_Intron|CDHR5_uc009ycc.3_Frame_Shift_Del_p.T412fs	NM_021924	NP_068743	Q9HBB8	CDHR5_HUMAN	Homo sapiens cadherin-related family member 5 (CDHR5), transcript variant 1, mRNA.	578	4 X 31 AA approximate tandem repeats.				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			NS(1)|breast(1)|endometrium(4)|kidney(1)|large_intestine(6)|lung(7)|ovary(1)|skin(2)	23						GGCTGAGAGGTTCCTGGCTCT	0.667													---	143	---	---	7	---					
abParts	0	broad.mit.edu	37	14	106370334	106370334	+	Splice_Site	DEL	G	-	-			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr14:106370334delG	uc021ser.1	-	3547		c.55170_splice	c.e3547-1		KIAA0125_uc001ysq.3_Intron|KIAA0125_uc001ysr.3_Intron					Parts of antibodies, mostly variable regions.																		ATGGGTTTTTGATGGACTCTG	0.552													---	223	---	---	7	---					
PPIP5K1	9677	broad.mit.edu	37	15	43827440	43827440	+	Frame_Shift_Del	DEL	A	-	-			TCGA-KL-8330-01A-11D-2310-10	TCGA-KL-8330-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	09537dce-c797-4b60-962a-d4c3cd6ab00a	1d82038a-3a67-4b82-8e8d-5ba2c855b563	g.chr15:43827440delA	uc001zrw.3	-	30	3938	c.3734delT	c.(3733-3735)atgfs	p.M1245fs	PPIP5K1_uc021sjw.1_Frame_Shift_Del_p.M1220fs|PPIP5K1_uc001zrx.2_Frame_Shift_Del_p.M1218fs|PPIP5K1_uc001zry.4_Frame_Shift_Del_p.M1220fs|PPIP5K1_uc021sjx.1_Frame_Shift_Del_p.M174fs	NM_001130858	NP_001124330	Q6PFW1	VIP1_HUMAN	Homo sapiens diphosphoinositol pentakisphosphate kinase 1 (PPIP5K1), transcript variant 5, mRNA.	1245					inositol metabolic process	cytosol	ATP binding|acid phosphatase activity|diphosphoinositol-pentakisphosphate kinase activity|inositol 1,3,4,5,6-pentakisphosphate kinase activity|inositol hexakisphosphate 5-kinase activity			large_intestine(1)	1						GCTGGTTTCCATAGGTGGCAC	0.587													---	152	---	---	7	---					
