Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PSG3	5671	broad.mit.edu	37	19	43233954	43233954	+	Missense_Mutation	SNP	A	T	T	rs1071709		TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr19:43233954A>T	uc002oue.3	-	3	1096	c.964T>A	c.(964-966)Tac>Aac	p.Y322N	PSG3_uc002ouf.3_Non-coding_Transcript|PSG3_uc002oug.1_Intron	NM_021016	NP_066296	Q16557	PSG3_HUMAN	Homo sapiens pregnancy specific beta-1-glycoprotein 3 (PSG3), mRNA.	322	Ig-like C2-type 2.				defense response|female pregnancy	extracellular region				central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(5)|lung(12)|ovary(1)|pancreas(1)|prostate(2)|skin(3)|stomach(1)|urinary_tract(1)	36		Prostate(69;0.00682)				GTGACTGGGTAACTGCGGATG	0.488000														44			4		0	0	1	0	0
KCNK10	54207	broad.mit.edu	37	14	88652066	88652066	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr14:88652066C>T	uc001xwm.3	-	6	1567	c.1445G>A	c.(1444-1446)cGg>cAg	p.R482Q	KCNK10_uc001xwn.3_Missense_Mutation_p.R482Q|KCNK10_uc001xwo.3_Missense_Mutation_p.R477Q	NM_138318	NP_612191	P57789	KCNKA_HUMAN	Homo sapiens potassium channel, subfamily K, member 10 (KCNK10), transcript variant 3, mRNA.	477					signal transduction	integral to membrane	potassium channel activity|voltage-gated ion channel activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(5)|lung(25)|ovary(3)|pancreas(2)|prostate(2)|skin(4)|upper_aerodigestive_tract(1)	47						GGAGTAATTCCGGAAGGTCTT	0.498000														292			8		0	0	1	0	0
MASTL	84930	broad.mit.edu	37	10	27447559	27447559	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr10:27447559A>G	uc001itm.3	+	1	871	c.268A>G	c.(268-270)Agc>Ggc	p.S90G	MASTL_uc001itl.3_Missense_Mutation_p.S90G|MASTL_uc009xkw.2_Missense_Mutation_p.S90G|MASTL_uc009xkx.2_Non-coding_Transcript	NM_001172303	NP_001165774	Q96GX5	GWL_HUMAN	Homo sapiens microtubule associated serine/threonine kinase-like (MASTL), transcript variant 1, mRNA.	90	Protein kinase.				G2/M transition of mitotic cell cycle|cell division|mitosis|negative regulation of protein phosphatase type 2A activity|regulation of cell cycle|response to DNA damage stimulus	centrosome|cleavage furrow|nucleus	ATP binding|protein phosphatase 2A binding|protein serine/threonine kinase activity			breast(3)|cervix(2)|endometrium(2)|large_intestine(7)|lung(9)|ovary(1)|pancreas(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	29						ACTAAGCAAAAGCCCATTCAT	0.338000														51			4		0	0	1	0	0
C3orf36	80111	broad.mit.edu	37	3	133647421	133647421	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr3:133647421G>A	uc003epz.1	-	0	1236	c.227C>T	c.(226-228)gCg>gTg	p.A76V		NM_025041	NP_079317	Q3SXR2	CC036_HUMAN	Homo sapiens chromosome 3 open reading frame 36 (C3orf36), mRNA.	76										breast(1)|endometrium(1)|large_intestine(2)|lung(1)|ovary(1)	6						GGGGTGTGGCGCGGCCCACTC	0.667000														92			21		0	0	1	0	0
PEX3	8504	broad.mit.edu	37	6	143780275	143780275	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr6:143780275A>G	uc003qjl.3	+	1	389	c.127A>G	c.(127-129)Agg>Ggg	p.R43G	PEX3_uc011edx.1_Missense_Mutation_p.R43G	NM_003630	NP_003621	P56589	PEX3_HUMAN	Homo sapiens peroxisomal biogenesis factor 3 (PEX3), mRNA.	43	Targeting to peroxisomes.				protein import into peroxisome membrane|transmembrane transport	integral to peroxisomal membrane	protein binding			endometrium(1)|large_intestine(9)|lung(4)|ovary(2)|skin(2)	18				OV - Ovarian serous cystadenocarcinoma(155;5.73e-06)|GBM - Glioblastoma multiforme(68;0.0117)		AATACAGGAAAGGGAGGCTGC	0.343000														160			4		0	0	1	0	0
KIAA0947	23379	broad.mit.edu	37	5	5464930	5464930	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr5:5464930A>G	uc003jdm.4	+	12	5705	c.5483A>G	c.(5482-5484)cAg>cGg	p.Q1828R		NM_015325	NP_056140	Q9Y2F5	K0947_HUMAN	Homo sapiens KIAA0947 (KIAA0947), mRNA.	1828										breast(2)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(5)|lung(14)|ovary(1)|prostate(4)|upper_aerodigestive_tract(1)	35						TTGGGGACTCAGCAGGATTCA	0.498000														88			16		0	0	1	0	0
GDA	9615	broad.mit.edu	37	9	74828816	74828816	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr9:74828816C>T	uc004air.3	+	4	696	c.487C>T	c.(487-489)Cgg>Tgg	p.R163W	GDA_uc011lse.2_Missense_Mutation_p.R89W|GDA_uc004aiq.3_Missense_Mutation_p.R163W|GDA_uc010mow.2_Non-coding_Transcript|GDA_uc011lsf.2_Missense_Mutation_p.R89W|GDA_uc004ais.3_Missense_Mutation_p.R121W|GDA_uc004ait.1_Missense_Mutation_p.R89W	NM_001242505	NP_001229434	Q9Y2T3	GUAD_HUMAN	Homo sapiens guanine deaminase (GDA), transcript variant 1, mRNA.	163					nervous system development|purine base metabolic process|purine nucleotide catabolic process	cytosol	guanine deaminase activity|zinc ion binding			central_nervous_system(4)|endometrium(1)|kidney(1)|large_intestine(1)|lung(20)|ovary(2)|skin(2)|urinary_tract(1)	32		Myeloproliferative disorder(762;0.0122)		Lung(182;0.0583)		ATTTGGACAGCGGGCATTTGT	0.348000														199			5		0	0	1	0	0
UBC	7316	broad.mit.edu	37	17	21730916	21730916	+	Missense_Mutation	SNP	G	T	T	rs111245273	by1000genomes	TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr17:21730916G>T	uc002gyy.3	+	1	343	c.218G>T	c.(217-219)cGg>cTg	p.R73L				P0CG48	UBC_HUMAN	SubName: Full=Uncharacterized protein;	225	Ubiquitin-like 1.				DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA repair|G1/S transition of mitotic cell cycle|I-kappaB kinase/NF-kappaB cascade|JNK cascade|M/G1 transition of mitotic cell cycle|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|S phase of mitotic cell cycle|T cell receptor signaling pathway|Toll signaling pathway|activation of MAPK activity|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|anti-apoptosis|apoptosis|cellular membrane organization|endosome transport|epidermal growth factor receptor signaling pathway|induction of apoptosis by extracellular signals|innate immune response|mRNA metabolic process|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of type I interferon production|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|nerve growth factor receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|stress-activated MAPK cascade|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway|viral reproduction	cytosol|endocytic vesicle membrane|endosome membrane|nucleoplasm|plasma membrane	protein binding	p.R73L(24)|p.R72S(1)		breast(3)|endometrium(4)|kidney(4)|large_intestine(2)|lung(13)|ovary(3)|prostate(4)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;6.17e-05)|Epithelial(86;0.000207)|all cancers(50;0.00308)		GTCCTGCGTCGGAGAGGTGGT	0.552000														37			3		0.004672	0.004672	1	1	0
PHACTR1	221692	broad.mit.edu	37	6	12719071	12719071	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr6:12719071G>A	uc003nah.2	+	2	468	c.95G>A	c.(94-96)gGa>gAa	p.G32E	PHACTR1_uc011dir.2_Missense_Mutation_p.G32E|PHACTR1_uc010jpc.3_Missense_Mutation_p.G32E|PHACTR1_uc003nag.2_Missense_Mutation_p.G32E|PHACTR1_uc003nai.3_Missense_Mutation_p.G32E	NM_030948	NP_112210	Q9C0D0	PHAR1_HUMAN	Homo sapiens phosphatase and actin regulator 1 (PHACTR1), transcript variant 1, mRNA.	32						cell junction|cytoplasm|synapse	actin binding|protein phosphatase inhibitor activity			breast(1)|endometrium(3)|kidney(2)|large_intestine(4)|lung(10)|ovary(1)|skin(2)|upper_aerodigestive_tract(3)	26	Breast(50;0.0427)|Ovarian(93;0.12)	all_hematologic(90;0.122)|Lung SC(78;0.195)	Epithelial(50;0.146)|BRCA - Breast invasive adenocarcinoma(129;0.239)			TACAGTCAAGGAGCTCAAGGT	0.388000														36			4		0	0	1	0	0
CCNT1	904	broad.mit.edu	37	12	49087549	49087549	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr12:49087549C>T	uc001rsd.4	-	8	1771	c.1448G>A	c.(1447-1449)cGc>cAc	p.R483H	CCNT1_uc009zkz.2_Missense_Mutation_p.R198H|CCNT1_uc021qxk.1_5'Flank	NM_001240	NP_001231	O60563	CCNT1_HUMAN	Homo sapiens cyclin T1 (CCNT1), mRNA.	483					cell cycle|cell division|interspecies interaction between organisms|positive regulation of viral transcription|protein phosphorylation|regulation of cyclin-dependent protein kinase activity|regulation of transcription, DNA-dependent|transcription elongation from RNA polymerase II promoter|viral reproduction	nucleoplasm	DNA binding|protein kinase binding			breast(3)|endometrium(1)|kidney(1)|large_intestine(4)|lung(13)|ovary(3)|skin(2)	27						GACTTTTATGCGCATTTTTAT	0.438000														112			5		0	0	1	0	0
PANX1	24145	broad.mit.edu	37	11	93913343	93913343	+	Missense_Mutation	SNP	A	G	G			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr11:93913343A>G	uc001per.3	+	3	1506	c.1121A>G	c.(1120-1122)aAg>aGg	p.K374R	PANX1_uc001peq.3_Missense_Mutation_p.K374R	NM_015368	NP_056183	Q96RD7	PANX1_HUMAN	Homo sapiens pannexin 1 (PANX1), mRNA.	374					positive regulation of interleukin-1 beta secretion|protein hexamerization|synaptic transmission	bleb|endoplasmic reticulum membrane|gap junction|integral to membrane	calcium channel activity|gap junction hemi-channel activity|leak channel activity|receptor binding			endometrium(2)|large_intestine(2)|lung(13)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	20		Acute lymphoblastic leukemia(157;2.31e-05)|all_hematologic(158;0.00824)				GGCATGATCAAGATGGATGTT	0.493000														116			4		0	0	1	0	0
PCDH12	51294	broad.mit.edu	37	5	141331089	141331089	+	Missense_Mutation	SNP	T	G	G			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr5:141331089T>G	uc003llx.3	-	1	4158	c.2947A>C	c.(2947-2949)Aat>Cat	p.N983H		NM_016580	NP_057664	Q9NPG4	PCD12_HUMAN	Homo sapiens protocadherin 12 (PCDH12), mRNA.	983					neuron recognition	integral to plasma membrane	calcium ion binding			breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(13)|lung(14)|ovary(3)|prostate(2)|skin(1)	38		all_hematologic(541;0.0999)	KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			AAGTACTTATTTCCTCGGTGG	0.557000											OREG0016877	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		103			4		0	0	1	0	0
GLI3	2737	broad.mit.edu	37	7	42079819	42079819	+	Silent	SNP	G	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr7:42079819G>T	uc011kbh.2	-	6	937	c.846C>A	c.(844-846)ccC>ccA	p.P282P	GLI3_uc011kbg.2_Silent_p.P223P	NM_000168	NP_000159	P10071	GLI3_HUMAN	Homo sapiens GLI family zinc finger 3 (GLI3), mRNA.	282					negative regulation of alpha-beta T cell differentiation|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of smoothened signaling pathway|negative regulation of transcription from RNA polymerase II promoter|negative thymic T cell selection|positive regulation of alpha-beta T cell differentiation|positive regulation of transcription from RNA polymerase II promoter|thymocyte apoptosis	cilium|cytosol|nucleolus	beta-catenin binding|histone acetyltransferase binding|histone deacetylase binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(2)|biliary_tract(1)|breast(4)|central_nervous_system(2)|endometrium(12)|kidney(7)|large_intestine(25)|lung(49)|ovary(3)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	112						CTGACAGCCTGGGGCTGGAGA	0.468000									Pallister-Hall syndrome;Greig Cephalopolysyndactyly					176			5		0.000274275	0.000283123	1	1	0
ELAVL4	1996	broad.mit.edu	37	1	50659551	50659551	+	Missense_Mutation	SNP	C	T	T	rs138779266		TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr1:50659551C>T	uc001csb.2	+	3	737	c.469C>T	c.(469-471)Cgt>Tgt	p.R157C	ELAVL4_uc001cry.3_Missense_Mutation_p.R160C|ELAVL4_uc001crz.3_Missense_Mutation_p.R157C|ELAVL4_uc001csa.3_Missense_Mutation_p.R174C|ELAVL4_uc001csc.3_Missense_Mutation_p.R157C|ELAVL4_uc009vyu.3_Missense_Mutation_p.R162C|ELAVL4_uc010omz.2_Missense_Mutation_p.R162C	NM_021952	NP_068771	P26378	ELAV4_HUMAN	Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) (ELAVL4), transcript variant 1, mRNA.	157	RRM 2.				mRNA processing		AU-rich element binding|mRNA 3'-UTR binding|nucleotide binding			NS(1)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|liver(2)|lung(5)|ovary(1)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(3)	32						GCAATACGGCCGTATCATCAC	0.453000														135			11		0	0	1	0	0
SSX3	10214	broad.mit.edu	37	X	48213477	48213477	+	Missense_Mutation	SNP	G	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chrX:48213477G>T	uc004djd.1	-	3	331	c.237C>A	c.(235-237)ttC>ttA	p.F79L	SSX3_uc004dje.3_Missense_Mutation_p.F79L|SSX3_uc010nic.3_Missense_Mutation_p.F79L	NM_021014	NP_066294	Q99909	SSX3_HUMAN	Homo sapiens synovial sarcoma, X breakpoint 3 (SSX3), transcript variant 1, mRNA.	79	KRAB-related.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	nucleic acid binding			endometrium(3)|large_intestine(1)|lung(9)	13						CATTCCCCTGGAAGTCTGTGA	0.468000														283			10		2.68362e-12	2.96124e-12	1	1	0
ARL5B	221079	broad.mit.edu	37	10	18957460	18957460	+	Splice_Site	SNP	T	C	C	rs148579997		TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr10:18957460T>C	uc001iqd.1	+	3	362	c.108_splice	c.e3-1	p.F36_splice		NM_178815	NP_848930	Q96KC2	ARL5B_HUMAN	Homo sapiens ADP-ribosylation factor-like 5B (ARL5B), mRNA.	36					small GTPase mediated signal transduction	intracellular	GTP binding			lung(1)|ovary(1)	2						TTTCAACAGCTTAATGAATGA	0.353000														94			4		0	0	1	0	0
DDX4	54514	broad.mit.edu	37	5	55111195	55111195	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr5:55111195C>T	uc003jqg.4	+	20	2140	c.2041C>T	c.(2041-2043)Cct>Tct	p.P681S	DDX4_uc010ivz.3_Missense_Mutation_p.P661S|DDX4_uc003jqh.4_Missense_Mutation_p.P647S|DDX4_uc003jqj.3_Missense_Mutation_p.P532S	NM_024415	NP_077726	Q9NQI0	DDX4_HUMAN	Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 (DDX4), transcript variant 1, mRNA.	681					multicellular organismal development|sperm motility	perinuclear region of cytoplasm|pi-body|piP-body	ATP binding|ATP-dependent helicase activity|nucleic acid binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|lung(8)|ovary(1)|skin(3)|upper_aerodigestive_tract(2)	24		Lung NSC(810;6.93e-05)|all_neural(839;0.00409)|Prostate(74;0.0107)|Breast(144;0.0544)|Ovarian(174;0.223)				TACATACATTCCTGGCTTCAG	0.353000														120			4		0	0	1	0	0
MEIS1	4211	broad.mit.edu	37	2	66667033	66667033	+	Missense_Mutation	SNP	A	C	C			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr2:66667033A>C	uc002sdu.3	+	2	755	c.298A>C	c.(298-300)Acc>Ccc	p.T100P	MEIS1_uc002sdt.3_Missense_Mutation_p.T100P|MEIS1_uc010yqh.2_Non-coding_Transcript|MEIS1_uc010yqi.2_Missense_Mutation_p.T35P|MEIS1_uc002sdw.1_5'Flank	NM_002398	NP_002389	O00470	MEIS1_HUMAN	Homo sapiens Meis homeobox 1 (MEIS1), mRNA.	100							sequence-specific DNA binding transcription factor activity			breast(1)|endometrium(1)|kidney(2)|large_intestine(6)|lung(10)|prostate(2)|skin(1)|urinary_tract(1)	24						AGCTACTTGTACCCCCCGCGA	0.483000														57			7		0	0	1	0	0
SURF4	6836	broad.mit.edu	37	9	136231848	136231848	+	Silent	SNP	T	C	C			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr9:136231848T>C	uc004cdj.3	-	4	541	c.411A>G	c.(409-411)gaA>gaG	p.E137E	SURF4_uc011mda.2_Silent_p.E128E|SURF4_uc010nal.3_Intron|SURF4_uc011mdd.2_Intron|SURF4_uc011mdb.2_Silent_p.E94E|SURF4_uc011mdc.2_Silent_p.E94E	NM_033161	NP_149351	O15260	SURF4_HUMAN	Homo sapiens surfeit 4 (SURF4), mRNA.	137						ER-Golgi intermediate compartment membrane|Golgi membrane|endoplasmic reticulum membrane|integral to membrane	protein binding			kidney(1)|large_intestine(2)|lung(5)	8				OV - Ovarian serous cystadenocarcinoma(145;5.32e-07)|Epithelial(140;4.56e-06)|all cancers(34;4.25e-05)		TGCTCTTCCCTTCAGAACGGG	0.572000														45			4		0	0	1	0	0
ZNF638	27332	broad.mit.edu	37	2	71653715	71653715	+	Silent	SNP	T	A	A			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr2:71653715T>A	uc002shx.3	+	23	5039	c.4716T>A	c.(4714-4716)gtT>gtA	p.V1572V	ZNF638_uc002shz.3_Silent_p.V1572V|ZNF638_uc002shy.3_Silent_p.V1572V|ZNF638_uc002sia.3_Silent_p.V1572V|ZNF638_uc002sib.1_3'UTR|ZNF638_uc002sic.3_Silent_p.V669V|ZNF638_uc002sid.3_5'UTR	NM_014497	NP_055312	Q14966	ZN638_HUMAN	Homo sapiens zinc finger protein 638 (ZNF638), transcript variant 1, mRNA.	1572					RNA splicing	cytoplasm|nuclear speck	RNA binding|double-stranded DNA binding|nucleotide binding|zinc ion binding			breast(4)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(16)|lung(28)|ovary(2)|pancreas(2)|prostate(1)|skin(2)|urinary_tract(1)	63						TCAAAAATGTTCCTTTCTCTG	0.393000														75			4		0	0	1	0	0
TCP1	6950	broad.mit.edu	37	6	160200278	160200278	+	Silent	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr6:160200278C>T	uc003qsr.3	-	11	1705	c.1470G>A	c.(1468-1470)ttG>ttA	p.L490L	TCP1_uc003qss.3_Silent_p.L335L	NM_030752	NP_001008897	P17987	TCPA_HUMAN	Homo sapiens t-complex 1 (TCP1), transcript variant 1, mRNA.	490					'de novo' posttranslational protein folding|tubulin complex assembly	Golgi apparatus|cell junction	ATP binding|unfolded protein binding			breast(1)|endometrium(4)|large_intestine(3)|lung(2)	10		Breast(66;1.53e-05)|Ovarian(120;0.024)		OV - Ovarian serous cystadenocarcinoma(65;4.05e-20)|BRCA - Breast invasive adenocarcinoma(81;1.1e-06)		TACCATTGCTCAAATCAAGAC	0.373000														55			33		0	0	1	0	0
AKT1S1	84335	broad.mit.edu	37	19	50374973	50374973	+	Splice_Site	SNP	T	A	A			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr19:50374973T>A	uc002pql.4	-	4	1184	c.458_splice	c.e4-1	p.D153_splice	AKT1S1_uc002pqn.4_Splice_Site_p.D153_splice|AKT1S1_uc002pqm.4_Splice_Site_p.D153_splice	NM_032375	NP_115751	Q96B36	AKTS1_HUMAN	Homo sapiens AKT1 substrate 1 (proline-rich) (AKT1S1), transcript variant 1, mRNA.	153					negative regulation of TOR signaling cascade|negative regulation of cell size|negative regulation of protein kinase activity|nerve growth factor receptor signaling pathway|neuroprotection|phosphatidylinositol-mediated signaling|regulation of survival gene product expression	cytosolic part	protein binding			kidney(1)|large_intestine(2)|lung(1)|upper_aerodigestive_tract(1)	5		all_lung(116;3.24e-07)|Lung NSC(112;1.6e-06)|all_neural(266;0.0459)|Ovarian(192;0.0728)		GBM - Glioblastoma multiforme(134;0.0116)|OV - Ovarian serous cystadenocarcinoma(262;0.0132)		CAGGCTGCCATCTGAAAGAGA	0.657000														57			5		0	0	1	0	0
TIAM1	7074	broad.mit.edu	37	21	32639202	32639202	+	Silent	SNP	G	T	T	rs139712298	byFrequency	TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr21:32639202G>T	uc002yow.1	-	4	559	c.87C>A	c.(85-87)tcC>tcA	p.S29S	TIAM1_uc011adk.1_Silent_p.S29S|TIAM1_uc011adl.1_Silent_p.S29S|TIAM1_uc002yox.1_Intron	NM_003253	NP_003244	Q13009	TIAM1_HUMAN	Homo sapiens T-cell lymphoma invasion and metastasis 1 (TIAM1), mRNA.	29					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cell-cell junction|cytosol	Rho guanyl-nucleotide exchange factor activity|receptor signaling protein activity			autonomic_ganglia(3)|breast(7)|central_nervous_system(2)|endometrium(13)|kidney(4)|large_intestine(33)|lung(44)|ovary(2)|prostate(3)|skin(2)|urinary_tract(2)	115						AGAGGCGCAGGGAGCGGGAAG	0.582000														52			3		0.00024832	0.000264875	1	1	0
OR10G7	390265	broad.mit.edu	37	11	123909471	123909471	+	Missense_Mutation	SNP	G	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr11:123909471G>T	uc001pzq.1	-	0	238	c.238C>A	c.(238-240)Ctg>Atg	p.L80M		NM_001004463	NP_001004463	Q8NGN6	O10G7_HUMAN	Homo sapiens olfactory receptor, family 10, subfamily G, member 7 (OR10G7), mRNA.	80					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(7)|large_intestine(6)|lung(20)|ovary(2)|prostate(2)|stomach(3)|urinary_tract(1)	47		Breast(109;0.00867)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.22)		BRCA - Breast invasive adenocarcinoma(274;4.88e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0521)		AAGGTCATCAGCATTTTGGGC	0.537000														685			10		2.62699e-14	3.00227e-14	1	1	0
AQR	9716	broad.mit.edu	37	15	35219284	35219284	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr15:35219284G>A	uc001ziv.3	-	12	1251	c.1070C>T	c.(1069-1071)gCa>gTa	p.A357V		NM_014691	NP_055506	O60306	AQR_HUMAN	Homo sapiens aquarius homolog (mouse) (AQR), mRNA.	357						catalytic step 2 spliceosome	RNA binding			breast(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(10)|lung(18)|ovary(1)|prostate(6)|skin(4)|upper_aerodigestive_tract(2)	57		Lung NSC(122;8.7e-10)|all_lung(180;1.47e-08)		all cancers(64;4.34e-18)|GBM - Glioblastoma multiforme(113;4.59e-07)|BRCA - Breast invasive adenocarcinoma(123;0.0283)		ATCTACTTCTGCCACATTTGA	0.338000														180			4		0	0	1	0	0
PCDHGC5	56097	broad.mit.edu	37	5	140720557	140720557	+	Silent	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr5:140720557C>T	uc003ljk.2	+	0	2204	c.2019C>T	c.(2017-2019)gcC>gcT	p.A673A	PCDHGC5_uc003lji.2_Intron|PCDHGC5_uc011dao.2_Silent_p.A673A	NM_018915	NP_061738	Q9Y5F6	PCDGM_HUMAN	Homo sapiens protocadherin gamma subfamily A, 2 (PCDHGA2), transcript variant 1, mRNA.	675	Cadherin 6.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			breast(2)|central_nervous_system(2)|endometrium(6)|kidney(4)|large_intestine(4)|lung(10)|ovary(4)|prostate(1)|urinary_tract(2)	35			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			ACATCCTGGCCGACCTGGGCA	0.687000														116			10		0	0	1	0	0
FAM75C2	645961	broad.mit.edu	37	9	90747122	90747122	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr9:90747122C>T	uc011lti.2	-	3	859	c.830G>A	c.(829-831)gGc>gAc	p.G277D		NM_001166137	NP_001159609	B4DYI2	B4DYI2_HUMAN	Homo sapiens family with sequence similarity 75, member C2 (FAM75C2), mRNA.	277																	GTTTGAGCCGCCAAGGCCTGA	0.557000														84			10		0	0	1	0	0
UBC	7316	broad.mit.edu	37	12	125396280	125396280	+	Missense_Mutation	SNP	G	A	A			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr12:125396280G>A	uc001ugs.4	-	1	2496	c.2038C>T	c.(2038-2040)Cgc>Tgc	p.R680C	UBC_uc001ugr.3_Non-coding_Transcript|UBC_uc001ugt.3_Missense_Mutation_p.R528C|UBC_uc001ugu.1_Missense_Mutation_p.R604C|UBC_uc001ugv.3_Missense_Mutation_p.R148C|UBC_uc021rge.1_Missense_Mutation_p.R680C	NM_021009	NP_066289	P0CG48	UBC_HUMAN	Homo sapiens ubiquitin C (UBC), mRNA.	680	Ubiquitin-like 9.				DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA repair|G1/S transition of mitotic cell cycle|I-kappaB kinase/NF-kappaB cascade|JNK cascade|M/G1 transition of mitotic cell cycle|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|S phase of mitotic cell cycle|T cell receptor signaling pathway|Toll signaling pathway|activation of MAPK activity|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|anti-apoptosis|apoptosis|cellular membrane organization|endosome transport|epidermal growth factor receptor signaling pathway|induction of apoptosis by extracellular signals|innate immune response|mRNA metabolic process|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of type I interferon production|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|nerve growth factor receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|stress-activated MAPK cascade|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway|viral reproduction	cytosol|endocytic vesicle membrane|endosome membrane|nucleoplasm|plasma membrane	protein binding			breast(3)|endometrium(4)|kidney(4)|large_intestine(2)|lung(13)|ovary(3)|prostate(4)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;6.17e-05)|Epithelial(86;0.000207)|all cancers(50;0.00308)		CCCCTCAAGCGCAGGACCAAG	0.448000														177			5		0	0	1	0	0
NRAP	4892	broad.mit.edu	37	10	115348753	115348753	+	Missense_Mutation	SNP	T	C	C			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr10:115348753T>C	uc001lal.3	-	41	5341	c.5177A>G	c.(5176-5178)aAg>aGg	p.K1726R	HABP2_uc021pyr.1_3'UTR|HABP2_uc001lai.4_3'UTR|NRAP_uc009xyb.3_Missense_Mutation_p.K478R|NRAP_uc001laj.3_Missense_Mutation_p.K1725R|NRAP_uc001lak.3_Missense_Mutation_p.K1690R	NM_198060	NP_932326	Q86VF7	NRAP_HUMAN	Homo sapiens nebulin-related anchoring protein (NRAP), transcript variant 2, mRNA.	1725						fascia adherens|muscle tendon junction	actin binding|muscle alpha-actinin binding|zinc ion binding			autonomic_ganglia(1)|breast(2)|central_nervous_system(4)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(18)|lung(39)|ovary(6)|prostate(3)|skin(1)|stomach(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	95		Colorectal(252;0.0233)|Breast(234;0.188)		Epithelial(162;0.00392)|all cancers(201;0.00569)		CAGGGCCTTCTTCTTTTTGAC	0.537000														82			4		0	0	1	0	0
SLC4A5	57835	broad.mit.edu	37	2	74454137	74454137	+	Missense_Mutation	SNP	C	T	T			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr2:74454137C>T	uc002sko.1	-	22	3087	c.3085G>A	c.(3085-3087)Gcg>Acg	p.A1029T	SLC4A5_uc002skl.3_Non-coding_Transcript|SLC4A5_uc002skn.3_Missense_Mutation_p.A1013T|SLC4A5_uc010ffc.1_Intron|SLC4A5_uc002skp.1_Missense_Mutation_p.A911T|SLC4A5_uc002sks.1_Missense_Mutation_p.G915D	NM_021196	NP_067019	Q9BY07	S4A5_HUMAN	Homo sapiens solute carrier family 4, sodium bicarbonate cotransporter, member 5 (SLC4A5), transcript variant a, mRNA.	1029						apical plasma membrane|integral to membrane	inorganic anion exchanger activity|sodium:bicarbonate symporter activity			breast(5)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(12)|lung(13)|ovary(5)|pancreas(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	48						CAGAGCACCGCCAGGCAGAGG	0.647000														101			6		0	0	1	0	0
NCAPH	23397	broad.mit.edu	37	2	97032995	97032995	+	Splice_Site	SNP	G	C	C			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr2:97032995G>C	uc002svz.1	+	15	1966	c.1882_splice	c.e15-1	p.V628_splice	NCAPH_uc010yum.1_Splice_Site_p.V604_splice|NCAPH_uc010yun.1_Splice_Site_p.V492_splice	NM_015341	NP_056156	Q15003	CND2_HUMAN	Homo sapiens non-SMC condensin I complex, subunit H (NCAPH), mRNA.	628					cell division|mitotic chromosome condensation	condensin complex|cytoplasm|microtubule cytoskeleton|nucleus				haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(11)|ovary(1)|prostate(1)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	28		Ovarian(717;0.0221)				CCTATTTCAGGTAAATAAAAT	0.363000														21			30		0	0	1	0	0
TAF1L	138474	broad.mit.edu	37	9	32632258	32632258	+	Missense_Mutation	SNP	T	C	C			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr9:32632258T>C	uc003zrg.1	-	0	3410	c.3320A>G	c.(3319-3321)gAc>gGc	p.D1107G	AX747113_uc003zrh.1_5'Flank	NM_153809	NP_722516	Q8IZX4	TAF1L_HUMAN	Homo sapiens TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like (TAF1L), mRNA.	1107					male meiosis|positive regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter|transcription initiation, DNA-dependent	transcription factor TFIID complex	DNA binding|TBP-class protein binding|histone acetyltransferase activity|protein serine/threonine kinase activity			breast(6)|central_nervous_system(4)|endometrium(14)|kidney(11)|large_intestine(32)|liver(2)|lung(68)|ovary(2)|pancreas(2)|prostate(7)|skin(9)|stomach(1)|upper_aerodigestive_tract(1)	159			LUSC - Lung squamous cell carcinoma(29;0.0181)	GBM - Glioblastoma multiforme(74;0.00301)		TGAGATGCTGTCTGTGTCAGT	0.438000														260			6		0	0	1	0	0
DCP1B	196513	broad.mit.edu	37	12	2113565	2113566	+	Frame_Shift_Ins	INS	-	C	C			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr12:2113565_2113566insC	uc001qjx.1	-	0	112_113	c.32_33insG	c.(31-33)ggafs	p.G11fs	DCP1B_uc010sdy.1_5'UTR|DCP1B_uc010sdz.2_Frame_Shift_Ins_p.G11fs	NM_152640	NP_689853	Q8IZD4	DCP1B_HUMAN	Homo sapiens DCP1 decapping enzyme homolog B (S. cerevisiae) (DCP1B), mRNA.	11					exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	cytosol|nucleus	hydrolase activity|protein binding			NS(1)|breast(1)|endometrium(6)|kidney(2)|large_intestine(3)|lung(10)|skin(1)	24			OV - Ovarian serous cystadenocarcinoma(31;0.00193)			CGCGCCCCTTTCCCACCAGGCC	0.649													---	139	---	---	7	---					
ZNF384	171017	broad.mit.edu	37	12	6777102	6777102	+	Frame_Shift_Del	DEL	C	-	-			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr12:6777102delC	uc010sfh.2	-	10	1782	c.1512delG	c.(1510-1512)cagfs	p.Q504fs	ZNF384_uc001qqa.3_Frame_Shift_Del_p.Q443fs|ZNF384_uc001qqd.3_Frame_Shift_Del_p.Q388fs	NM_001135734	NP_001129206	Q8TF68	ZN384_HUMAN	Homo sapiens zinc finger protein 384 (ZNF384), transcript variant 7, mRNA.	504	Gln-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding		EWSR1/ZNF384(4)	breast(3)|central_nervous_system(3)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(1)|lung(6)|prostate(1)|urinary_tract(1)	18						gctgctgctgctgctgctgct	0.682			T	"""EWSR1, TAF15 """	ALL								---	70	---	---	7	---					
ZSCAN10	84891	broad.mit.edu	37	16	3139359	3139359	+	Frame_Shift_Del	DEL	A	-	-			TCGA-KL-8340-01A-11D-2310-10	TCGA-KL-8340-11A-01D-2310-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d113ce88-04ab-4675-b363-92f80c28de34	44123123-63e3-46bd-85ee-c66a37c942a3	g.chr16:3139359delA	uc002ctv.1	-	4	1999	c.1911delT	c.(1909-1911)tgtfs	p.C637fs	ZSCAN10_uc002cty.1_Frame_Shift_Del_p.C298fs|ZSCAN10_uc002ctw.1_Frame_Shift_Del_p.C555fs|ZSCAN10_uc002ctx.1_Frame_Shift_Del_p.C565fs	NM_032805	NP_116194	Q96SZ4	ZSC10_HUMAN	Homo sapiens zinc finger and SCAN domain containing 10 (ZSCAN10), mRNA.	637					negative regulation of transcription, DNA-dependent|viral reproduction	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|cervix(3)|endometrium(3)|kidney(1)|lung(8)|ovary(2)|prostate(1)|skin(4)|urinary_tract(1)	24						CGCACGTCTGACAGCTGTAGG	0.716													---	4	---	---	2	---					
