Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
DUSP11	8446	broad.mit.edu	37	2	74007178	74007178	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr2:74007178G>A	uc002sjp.3	-	0	107	c.65C>T	c.(64-66)tCt>tTt	p.S22F	DUSP11_uc002sjq.4_Missense_Mutation_p.S22F	NM_003584	NP_003575	O75319	DUS11_HUMAN	Homo sapiens dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) (DUSP11), mRNA.	0					RNA processing	nucleus	RNA binding|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity			breast(1)|cervix(1)|endometrium(1)|large_intestine(4)|lung(4)|skin(1)	12						GCCAGGATAAGACCCTAAACA	0.637000											OREG0014714	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		67			31		0	0	1	0	0
HSPA14	51182	broad.mit.edu	37	10	14890641	14890641	+	Silent	SNP	G	A	A			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr10:14890641G>A	uc001inf.3	+	3	396	c.255G>A	c.(253-255)gcG>gcA	p.A85A	HSPA14_uc010qbw.2_Silent_p.A85A	NM_016299	NP_057383	Q0VDF9	HSP7E_HUMAN	Homo sapiens heat shock 70kDa protein 14 (HSPA14), transcript variant 1, mRNA.	85			A -> V (in a breast cancer sample; somatic mutation).		'de novo' cotranslational protein folding	cytosol	ATP binding|protein binding	p.A85V(2)		breast(4)|endometrium(2)|kidney(2)|large_intestine(3)|lung(4)|ovary(2)	17						AATACATCGCGGAAAGTAAAT	0.328000														94			4		0	0	1	0	0
GOLGA3	2802	broad.mit.edu	37	12	133357472	133357472	+	Missense_Mutation	SNP	T	C	C			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr12:133357472T>C	uc001ukz.1	-	17	4053	c.3494A>G	c.(3493-3495)gAg>gGg	p.E1165G	GOLGA3_uc021rgt.1_Non-coding_Transcript|GOLGA3_uc001ula.1_Missense_Mutation_p.E1165G	NM_005895	NP_005886	Q08378	GOGA3_HUMAN	Homo sapiens golgin A3 (GOLGA3), transcript variant 1, mRNA.	1165					intra-Golgi vesicle-mediated transport	Golgi cisterna membrane|Golgi transport complex	protein binding|transporter activity			breast(1)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(4)|lung(33)|ovary(3)|pancreas(1)|prostate(4)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	64	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.0176)|Lung NSC(355;0.204)		OV - Ovarian serous cystadenocarcinoma(86;2.27e-08)|Epithelial(86;3.34e-07)|all cancers(50;9.4e-06)		GCGATCCTCCTCTTCTTTGCG	0.542000														24			3		0	0	1	0	0
TUB	7275	broad.mit.edu	37	11	8120345	8120345	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr11:8120345G>A	uc001mga.3	+	8	1188	c.1039G>A	c.(1039-1041)Gga>Aga	p.G347R	TUB_uc010rbk.2_Missense_Mutation_p.G353R|TUB_uc001mfy.3_Missense_Mutation_p.G402R	NM_177972	NP_813977	P50607	TUB_HUMAN	Homo sapiens tubby homolog (mouse) (TUB), transcript variant 2, mRNA.	347					phagocytosis|positive regulation of phagocytosis|response to stimulus	cytoplasm|extracellular region|nucleus|plasma membrane				breast(1)|cervix(1)|endometrium(9)|large_intestine(7)|lung(5)|ovary(1)|stomach(1)|upper_aerodigestive_tract(1)	26		all_lung(207;6.91e-20)|Lung NSC(207;3.36e-17)		Epithelial(150;1.69e-62)|BRCA - Breast invasive adenocarcinoma(625;8.54e-06)|LUSC - Lung squamous cell carcinoma(625;0.000184)		TTATGACAATGGAGTCAACCC	0.517000											OREG0020732	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		156			6		0	0	1	0	0
WNT3	7473	broad.mit.edu	37	17	44847153	44847153	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr17:44847153C>T	uc002ikv.2	-	2	703	c.584G>A	c.(583-585)cGc>cAc	p.R195H		NM_030753	NP_110380	P56703	WNT3_HUMAN	Homo sapiens wingless-type MMTV integration site family, member 3 (WNT3), mRNA.	195					Spemann organizer formation at the anterior end of the primitive streak|Wnt receptor signaling pathway, calcium modulating pathway|canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt receptor signaling pathway involved in osteoblast differentiation|cellular response to retinoic acid|dorsal/ventral axis specification|embryonic forelimb morphogenesis|embryonic hindlimb morphogenesis|embryonic pattern specification|head morphogenesis|hemopoietic stem cell proliferation|inner ear morphogenesis|limb bud formation|mammary gland epithelium development|mesoderm formation|midbrain-hindbrain boundary development|negative regulation of fat cell differentiation|positive regulation of cell proliferation	early endosome|extracellular space|late endosome|membrane fraction|membrane raft|plasma membrane|proteinaceous extracellular matrix	frizzled binding|frizzled-2 binding|signal transducer activity			endometrium(2)|large_intestine(6)|lung(4)|prostate(1)	13			BRCA - Breast invasive adenocarcinoma(9;0.0257)			GCTCACCGTGCGGCCCGCCTC	0.701000														32			19		0	0	1	0	0
MS4A14	84689	broad.mit.edu	37	11	60165391	60165391	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr11:60165391G>A	uc001npj.3	+	1	770	c.205G>A	c.(205-207)Ggt>Agt	p.G69S	MS4A14_uc001npi.3_Intron|MS4A14_uc001npn.3_5'UTR|MS4A14_uc001npk.3_Missense_Mutation_p.G69S|MS4A14_uc001npl.3_5'UTR|MS4A14_uc001npm.3_5'UTR	NM_032597	NP_115986	Q96JA4	M4A14_HUMAN	Homo sapiens membrane-spanning 4-domains, subfamily A, member 14 (MS4A14), transcript variant 1, mRNA.	69						integral to membrane	receptor activity			autonomic_ganglia(1)|breast(4)|cervix(1)|endometrium(2)|kidney(5)|large_intestine(9)|lung(31)|ovary(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	62						TAATTACATCGGTTTCTCCCA	0.433000														163			4		0	0	1	0	0
CHST6	4166	broad.mit.edu	37	16	75512651	75512651	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr16:75512651C>T	uc021tlj.1	-	0	1076	c.1076G>A	c.(1075-1077)cGg>cAg	p.R359Q	CHST6_uc002fef.3_Missense_Mutation_p.R359Q|CHST6_uc002feg.1_Non-coding_Transcript|CHST6_uc002feh.1_Missense_Mutation_p.R359Q	NM_021615	NP_067628	Q9GZX3	CHST6_HUMAN	Homo sapiens carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 (CHST6), mRNA.	359					N-acetylglucosamine metabolic process|keratan sulfate biosynthetic process	Golgi membrane|integral to membrane	N-acetylglucosamine 6-O-sulfotransferase activity			central_nervous_system(1)|cervix(1)|endometrium(1)|large_intestine(1)|lung(7)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	17						GTACACAGGCCGGTAGCCCAG	0.662000														87			3		0	0	1	0	0
CNTLN	54875	broad.mit.edu	37	9	17409364	17409364	+	Missense_Mutation	SNP	A	G	G			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr9:17409364A>G	uc003zmz.2	+	15	2712	c.2686A>G	c.(2686-2688)Acg>Gcg	p.T896A	CNTLN_uc003zmy.3_Missense_Mutation_p.T897A|CNTLN_uc010mio.3_Missense_Mutation_p.T576A	NM_017738	NP_060208	Q9NXG0	CNTLN_HUMAN	Homo sapiens centlein, centrosomal protein (CNTLN), transcript variant 1, mRNA.	897						centriole|membrane	two-component sensor activity			breast(6)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(5)|kidney(3)|large_intestine(10)|lung(17)|ovary(1)|pancreas(1)|prostate(3)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	53				GBM - Glioblastoma multiforme(50;6.14e-10)		AATAAGTCCTACGGAAGATGG	0.358000														180			4		0	0	1	0	0
MUC4	4585	broad.mit.edu	37	3	195513758	195513758	+	Missense_Mutation	SNP	G	C	C			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr3:195513758G>C	uc021xjp.1	-	1	4849	c.4693C>G	c.(4693-4695)Cac>Gac	p.H1565D	MUC4_uc003fvo.3_Intron|MUC4_uc003fvp.3_Intron	NM_018406	NP_060876	Q99102	MUC4_HUMAN	Homo sapiens mucin 4, cell surface associated (MUC4), transcript variant 1, mRNA.	1050	VWFD.				cell-matrix adhesion	integral to plasma membrane|proteinaceous extracellular matrix	ErbB-2 class receptor binding|extracellular matrix constituent, lubricant activity	p.H1565D(1)		NS(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(5)|lung(23)|ovary(3)|prostate(8)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	51	all_cancers(143;1.11e-08)|Ovarian(172;0.0634)|Breast(254;0.206)	Lung NSC(153;0.191)	Epithelial(36;3.72e-24)|all cancers(36;6.22e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.1e-18)|Lung(62;4.65e-05)|LUSC - Lung squamous cell carcinoma(58;5.31e-05)	GBM - Glioblastoma multiforme(46;2.37e-05)		GGGGTGGTGTGACCTGTGGAT	0.572000														54			3		0	0	1	0	0
TSHZ1	10194	broad.mit.edu	37	18	72997839	72997839	+	Silent	SNP	A	C	C			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr18:72997839A>C	uc002lly.3	+	1	905	c.342A>C	c.(340-342)acA>acC	p.T114T	TSHZ1_uc021uln.1_Silent_p.T114T	NM_005786	NP_005777	Q6ZSZ6	TSH1_HUMAN	Homo sapiens teashirt zinc finger homeobox 1 (TSHZ1), mRNA.	159	Ser-rich.					nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(11)|liver(1)|lung(14)|ovary(1)|skin(6)|upper_aerodigestive_tract(2)	42		Esophageal squamous(42;0.129)|Prostate(75;0.142)|Melanoma(33;0.211)		Colorectal(1;0.000501)|READ - Rectum adenocarcinoma(2;0.00226)|BRCA - Breast invasive adenocarcinoma(31;0.246)		ccacccccacaccccccacct	0.642000														11			4		0	0	1	0	0
OR5M10	390167	broad.mit.edu	37	11	56344713	56344713	+	Missense_Mutation	SNP	A	T	T	rs140389540	by1000genomes	TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr11:56344713A>T	uc001niz.1	-	0	485	c.485T>A	c.(484-486)cTg>cAg	p.L162Q	OR8U8_uc001nit.2_Intron	NM_001004741	NP_001004741	Q6IEU7	OR5MA_HUMAN	Homo sapiens olfactory receptor, family 5, subfamily M, member 10 (OR5M10), mRNA.	162					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			central_nervous_system(1)|cervix(1)|endometrium(2)|large_intestine(2)|lung(15)|upper_aerodigestive_tract(2)|urinary_tract(2)	25						GTGAAAGGTCAGCAGTGTCTG	0.468000														254			4		0	0	1	0	0
NBPF10	100132406	broad.mit.edu	37	1	145299779	145299779	+	Silent	SNP	C	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr1:145299779C>T	uc021oul.1	+	5	863	c.828C>T	c.(826-828)gcC>gcT	p.A276A	NBPF10_uc021ots.1_Intron|NBPF10_uc010oye.2_Intron|NBPF10_uc021ouk.1_Silent_p.A276A|NBPF10_uc010oyi.2_5'Flank|NBPF10_uc001emq.1_Intron	NM_001039703	NP_001034792	A6NDV3	A6NDV3_HUMAN	Homo sapiens neuroblastoma breakpoint family, member 10 (NBPF10), mRNA.	276										NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		TGGTATCAGCCGGCCCTTTGT	0.498000														57			3		0	0	1	0	0
LAMA3	3909	broad.mit.edu	37	18	21404467	21404467	+	Missense_Mutation	SNP	G	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr18:21404467G>T	uc002kuq.3	+	20	2595	c.2509G>T	c.(2509-2511)Gac>Tac	p.D837Y	LAMA3_uc002kur.3_Missense_Mutation_p.D837Y	NM_198129	NP_937762	Q16787	LAMA3_HUMAN	Homo sapiens laminin, alpha 3 (LAMA3), transcript variant 1, mRNA.	837	Domain IV 1 (domain IV B).				cell adhesion|epidermis development|hemidesmosome assembly|regulation of cell adhesion|regulation of cell migration|regulation of embryonic development	laminin-1 complex	receptor binding|structural molecule activity	p.D837N(2)|p.A836T(1)		NS(2)|breast(4)|central_nervous_system(3)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(24)|lung(54)|ovary(8)|prostate(6)|skin(7)|urinary_tract(4)	128	all_cancers(21;7.81e-05)|all_epithelial(16;4.45e-07)|Lung NSC(20;0.00156)|all_lung(20;0.00508)|Colorectal(14;0.0202)|Ovarian(20;0.17)				Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)	TGGTTTTGCAGACCCATTTTC	0.458000														80			7		1.06961e-07	1.06961e-07	1	1	0
CALU	813	broad.mit.edu	37	7	128407599	128407599	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr7:128407599C>T	uc022ald.1	+	6	1700	c.757C>T	c.(757-759)Cgt>Tgt	p.R253C	CALU_uc022alg.1_Missense_Mutation_p.R171C|CALU_uc022alh.1_Missense_Mutation_p.R171C|CALU_uc022ali.1_Missense_Mutation_p.R93C|CALU_uc003vns.3_Missense_Mutation_p.R245C|CALU_uc003vnr.3_Missense_Mutation_p.R253C|CALU_uc003vnq.3_Missense_Mutation_p.R245C|CALU_uc022ale.1_Intron|CALU_uc022alf.1_Missense_Mutation_p.R94C	NM_001199672	NP_001186601	O43852	CALU_HUMAN	Homo sapiens calumenin (CALU), transcript variant 4, mRNA.	245	EF-hand 5.				platelet activation|platelet degranulation	Golgi apparatus|extracellular region|melanosome|sarcoplasmic reticulum lumen	calcium ion binding|protein binding			kidney(2)|large_intestine(3)|lung(5)	10						GGATAAGAACCGTGATGGGAA	0.488000														93			3		0	0	1	0	0
EPT1	85465	broad.mit.edu	37	2	26608003	26608003	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr2:26608003G>A	uc021veu.1	+	7	1055	c.908G>A	c.(907-909)aGt>aAt	p.S303N	EPT1_uc010eyl.1_Non-coding_Transcript	NM_033505		Q9C0D9	EPT1_HUMAN	Homo sapiens ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) (EPT1), mRNA.	303					phospholipid biosynthetic process	integral to membrane	ethanolaminephosphotransferase activity|metal ion binding										TTTGCCAACAGTACAGTAAGA	0.284000														52			19		0	0	1	0	0
ZNF629	23361	broad.mit.edu	37	16	30794552	30794552	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr16:30794552C>T	uc002dzs.1	-	2	1305	c.1097G>A	c.(1096-1098)cGg>cAg	p.R366Q		NM_001080417	NP_001073886	Q9UEG4	ZN629_HUMAN	Homo sapiens zinc finger protein 629 (ZNF629), mRNA.	366					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(3)|kidney(1)|large_intestine(4)|lung(8)|ovary(1)|prostate(3)|urinary_tract(1)	22			Colorectal(24;0.198)			CAGGTGAGTCCGCTGGTGCTT	0.662000														79			41		0	0	1	0	0
LRBA	987	broad.mit.edu	37	4	151842427	151842427	+	Silent	SNP	A	G	G			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr4:151842427A>G	uc010ipj.3	-	4	812	c.568T>C	c.(568-570)Ttg>Ctg	p.L190L	LRBA_uc003ilu.4_Silent_p.L190L|LRBA_uc010ipk.1_Silent_p.L109L	NM_006726	NP_006717	P50851	LRBA_HUMAN	Homo sapiens LPS-responsive vesicle trafficking, beach and anchor containing (LRBA), transcript variant 2, mRNA.	190						Golgi apparatus|endoplasmic reticulum|integral to membrane|lysosome|plasma membrane	protein binding			breast(6)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(20)|lung(32)|ovary(4)|prostate(6)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	91	all_hematologic(180;0.151)					ACAGACAGCAACTTCCCAGCA	0.338000														236			5		0	0	1	0	0
COL16A1	1307	broad.mit.edu	37	1	32149324	32149324	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr1:32149324C>T	uc001btk.1	-	33	2728	c.2363G>A	c.(2362-2364)gGa>gAa	p.G788E	COL16A1_uc001btj.1_Missense_Mutation_p.G617E|COL16A1_uc001btl.4_Missense_Mutation_p.G788E	NM_001856	NP_001847	Q07092	COGA1_HUMAN	Homo sapiens collagen, type XVI, alpha 1 (COL16A1), mRNA.	788	Triple-helical region 5 (COL5) with 3 imperfections.				cell adhesion|female pregnancy|integrin-mediated signaling pathway	collagen type XVI	integrin binding|structural molecule activity			breast(4)|central_nervous_system(2)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(7)|lung(15)|ovary(8)|prostate(4)	48		Myeloproliferative disorder(586;0.0255)|Ovarian(437;0.0423)|all_neural(195;0.0837)|Breast(348;0.116)		STAD - Stomach adenocarcinoma(196;0.059)		TCCCTGGACTCCCCTTCCTGG	0.607000														49			3		0	0	1	0	0
FMN2	56776	broad.mit.edu	37	1	240371393	240371393	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr1:240371393C>T	uc010pye.2	+	5	3518	c.3293C>T	c.(3292-3294)gCg>gTg	p.A1098V	FMN2_uc010pyd.2_Missense_Mutation_p.A1094V	NM_020066	NP_064450	Q9NZ56	FMN2_HUMAN	Homo sapiens formin 2 (FMN2), mRNA.	1094	FH1.|Pro-rich.				actin cytoskeleton organization|establishment of meiotic spindle localization|intracellular signal transduction|meiotic chromosome movement towards spindle pole|meiotic metaphase I|multicellular organismal development|oogenesis|polar body extrusion after meiotic divisions		actin binding			NS(1)|breast(7)|central_nervous_system(6)|cervix(1)|endometrium(14)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(13)|lung(87)|ovary(6)|pancreas(3)|prostate(12)|skin(7)|stomach(2)|upper_aerodigestive_tract(6)|urinary_tract(2)	178	Ovarian(103;0.127)	all_cancers(173;0.013)	OV - Ovarian serous cystadenocarcinoma(106;0.0106)			CTACCCGGAGCGGGCATACCC	0.731000														36			9		0	0	1	0	0
TPP2	7174	broad.mit.edu	37	13	103328696	103328696	+	Silent	SNP	A	G	G			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr13:103328696A>G	uc001vpi.4	+	27	3694	c.3591A>G	c.(3589-3591)agA>agG	p.R1197R		NM_003291	NP_003282	P29144	TPP2_HUMAN	Homo sapiens tripeptidyl peptidase II (TPP2), mRNA.	1197					proteolysis	cytoplasm|nucleus	aminopeptidase activity|serine-type endopeptidase activity|tripeptidyl-peptidase activity			breast(2)|endometrium(5)|kidney(2)|large_intestine(12)|lung(21)|ovary(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	52	all_neural(89;0.0438)|Medulloblastoma(90;0.163)|Lung SC(71;0.184)					TGTATGGGAGAGGCCTTAAAT	0.264000														214			5		0	0	1	0	0
KCMF1	56888	broad.mit.edu	37	2	85262268	85262268	+	Frame_Shift_Del	DEL	C	-	-			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr2:85262268delC	uc002sox.4	+	2	658	c.314delC	c.(313-315)tcafs	p.S105fs		NM_020122	NP_064507	Q9P0J7	KCMF1_HUMAN	Homo sapiens potassium channel modulatory factor 1 (KCMF1), mRNA.	105						intracellular	ligase activity|zinc ion binding			ovary(3)	3						GCAGAAACATCAACAGAAGTG	0.373													---	52	---	---	24	---					
ATAT1	79969	broad.mit.edu	37	6	30610646	30610646	+	Frame_Shift_Del	DEL	T	-	-			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr6:30610646delT	uc003nqv.3	+	9	1108	c.790delT	c.(790-792)tcafs	p.S264fs	ATAT1_uc003nqr.4_Frame_Shift_Del_p.S276fs|ATAT1_uc003nqs.4_Frame_Shift_Del_p.S253fs|ATAT1_uc003rdd.3_Frame_Shift_Del_p.S253fs|ATAT1_uc003rdc.3_Frame_Shift_Del_p.S276fs|ATAT1_uc011dmm.2_Frame_Shift_Del_p.S241fs	NM_001031722	NP_001026892	Q5SQI0	ATAT_HUMAN	Homo sapiens alpha tubulin acetyltransferase 1 (ATAT1), transcript variant 1, mRNA.	276							tubulin N-acetyltransferase activity			cervix(1)|endometrium(1)|large_intestine(1)|lung(1)|ovary(3)|prostate(1)|upper_aerodigestive_tract(1)	9						CCTGGGAAACTCACCAGAACG	0.682													---	70	---	---	7	---					
WIPF3	644150	broad.mit.edu	37	7	29924113	29924114	+	Frame_Shift_Ins	INS	-	C	C			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr7:29924113_29924114insC	uc022aaz.1	+	4	1185_1186	c.1003_1004insC	c.(1003-1005)gccfs	p.A335fs	WIPF3_uc003taj.2_Frame_Shift_Ins_p.A335fs	NM_001080529	NP_001073998	B8ZZV2	B8ZZV2_HUMAN	Homo sapiens WAS/WASL interacting protein family, member 3 (WIPF3), mRNA.	335										breast(2)|large_intestine(3)|lung(6)|ovary(1)	12						CAGCTTCCAGGCCCCACCGCAG	0.668													---	106	---	---	7	---					
HNRNPKP3	399881	broad.mit.edu	37	11	43283606	43283606	+	RNA	DEL	A	-	-			TCGA-KM-8439-01A-11D-2310-10	TCGA-KM-8439-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d3b0b87-5fc5-4d09-9c63-4d5fc4bc46d0	1f433ac7-b321-46a9-87ac-c72ad5b1b4e5	g.chr11:43283606delA	uc001mxe.1	-	1		c.1330delT								Homo sapiens heterogeneous nuclear ribonucleoprotein K pseudogene 3 (HNRNPKP3), non-coding RNA.																		AAGCAAATGTAAAAAAAAAAA	0.388													---	7	---	---	7	---					
