Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
HYDIN	54768	broad.mit.edu	37	GL000192.1	311414	311414	+	RNA	SNP	T	C	C			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chrGL000192.1:311414T>C	uc010yij.1	-	6		c.955A>G			HYDIN_uc021vdl.1_Non-coding_Transcript	NM_017558		Q4G0P3	HYDIN_HUMAN	Homo sapiens HYDIN, axonemal central pair apparatus protein (HYDIN), transcript variant 2, mRNA.											breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(17)|lung(12)|ovary(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)	43		Ovarian(137;0.0654)				CGTATTTCTGTACAGTGTTGG	0.532000														17			3		0	0	1	0	0
SEMA6B	10501	broad.mit.edu	37	19	4557004	4557004	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr19:4557004G>A	uc010dud.2	-	4	590	c.328C>T	c.(328-330)Ccc>Tcc	p.P110S	SEMA6B_uc010xih.1_Missense_Mutation_p.P110S	NM_032108	NP_115484	Q9H3T3	SEM6B_HUMAN	Homo sapiens sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B (SEMA6B), mRNA.	110	Sema.				cell differentiation|nervous system development	integral to membrane	receptor activity			breast(1)|central_nervous_system(2)|large_intestine(4)|lung(11)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	21		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0149)|STAD - Stomach adenocarcinoma(1328;0.18)		ATGTCGCTGGGGTTAGATCTC	0.627000														22			5		0	0	1	0	0
DRD3	1814	broad.mit.edu	37	3	113890761	113890761	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr3:113890761G>A	uc003ebd.2	-	2	502	c.79C>T	c.(79-81)Cgc>Tgc	p.R27C	DRD3_uc010hqn.1_Missense_Mutation_p.R27C|DRD3_uc003ebb.1_Missense_Mutation_p.R27C|DRD3_uc003ebc.1_Missense_Mutation_p.R27C	NM_000796	NP_000787	P35462	DRD3_HUMAN	Homo sapiens dopamine receptor D3 (DRD3), transcript variant a, mRNA.	27					G-protein coupled receptor internalization|activation of adenylate cyclase activity by dopamine receptor signaling pathway|arachidonic acid secretion|behavioral response to cocaine|cellular calcium ion homeostasis|circadian regulation of gene expression|inhibition of adenylate cyclase activity by dopamine receptor signaling pathway|locomotory behavior|musculoskeletal movement, spinal reflex action|negative regulation of blood pressure|negative regulation of oligodendrocyte differentiation|negative regulation of protein kinase B signaling cascade|negative regulation of protein secretion|positive regulation of dopamine receptor signaling pathway|positive regulation of mitosis|prepulse inhibition|regulation of dopamine secretion|response to drug|response to histamine|response to morphine|social behavior|visual learning	integral to plasma membrane	dopamine D3 receptor activity|drug binding			central_nervous_system(2)|endometrium(1)|kidney(2)|large_intestine(4)|liver(1)|lung(23)|ovary(1)|pancreas(1)|skin(1)	36					Apomorphine(DB00714)|Chlorprothixene(DB01239)|Cocaine(DB00907)|Methotrimeprazine(DB01403)|Olanzapine(DB00334)|Pramipexole(DB00413)|Ropinirole(DB00268)|Ziprasidone(DB00246)	GCATGTGGGCGGGCCTGGCTG	0.627000														39			35		0	0	1	0	0
RYR1	6261	broad.mit.edu	37	19	38976258	38976258	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr19:38976258C>T	uc002oit.3	+	33	5093	c.4963C>T	c.(4963-4965)Cgc>Tgc	p.R1655C	RYR1_uc002oiu.3_Missense_Mutation_p.R1655C	NM_000540	NP_000531	P21817	RYR1_HUMAN	Homo sapiens ryanodine receptor 1 (skeletal) (RYR1), transcript variant 1, mRNA.	1655	6 X approximate repeats.				muscle contraction|release of sequestered calcium ion into cytosol|response to caffeine|response to hypoxia	I band|cell cortex|cytosol|integral to plasma membrane|junctional sarcoplasmic reticulum membrane|smooth endoplasmic reticulum|terminal cisterna	calcium ion binding|calmodulin binding|receptor activity|ryanodine-sensitive calcium-release channel activity			NS(4)|autonomic_ganglia(2)|breast(3)|central_nervous_system(5)|endometrium(26)|haematopoietic_and_lymphoid_tissue(3)|kidney(34)|large_intestine(42)|liver(1)|lung(106)|ovary(11)|pancreas(5)|prostate(9)|skin(12)|stomach(11)|upper_aerodigestive_tract(4)|urinary_tract(7)	285	all_cancers(60;7.91e-06)		Lung(45;0.00172)|LUSC - Lung squamous cell carcinoma(53;0.00272)		Dantrolene(DB01219)	GCTGTCGGAGCGCCTGGACCT	0.627000														22			11		0	0	1	0	0
EYA1	2138	broad.mit.edu	37	8	72211306	72211306	+	Missense_Mutation	SNP	G	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr8:72211306G>T	uc003xyu.3	-	8	1442	c.802C>A	c.(802-804)Caa>Aaa	p.Q268K	EYA1_uc003xyt.4_Missense_Mutation_p.Q235K|EYA1_uc003xyr.4_Missense_Mutation_p.Q263K|EYA1_uc010lzf.3_Missense_Mutation_p.Q195K|EYA1_uc003xys.4_Missense_Mutation_p.Q268K|EYA1_uc011lfe.2_Missense_Mutation_p.Q262K|EYA1_uc003xyv.3_Missense_Mutation_p.Q146K	NM_000503	NP_742055	Q99502	EYA1_HUMAN	Homo sapiens eyes absent homolog 1 (Drosophila) (EYA1), transcript variant 3, mRNA.	268					double-strand break repair|histone dephosphorylation|positive regulation of DNA repair|protein sumoylation|regulation of transcription, DNA-dependent|response to ionizing radiation|sensory perception of sound|transcription, DNA-dependent	cytoplasm|nucleus	metal ion binding|protein tyrosine phosphatase activity			NS(2)|breast(3)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(8)|lung(15)|ovary(4)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)	44	Breast(64;0.046)		Epithelial(68;0.0837)|all cancers(69;0.247)			GTAACTGCTTGGCTGGTGATG	0.433000														398			13		6.31663e-08	6.46019e-08	1	1	0
KLF15	28999	broad.mit.edu	37	3	126071789	126071789	+	Splice_Site	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr3:126071789G>A	uc011bkk.1	-	2	158	c.-24_splice	c.e2-1			NM_014079	NP_054798	Q9UIH9	KLF15_HUMAN	Homo sapiens Kruppel-like factor 15 (KLF15), mRNA.							nucleus	DNA binding|zinc ion binding			endometrium(1)|lung(7)|ovary(2)|skin(2)	12				GBM - Glioblastoma multiforme(114;0.147)		TGCCGGTGGCGGCTGCAGGAA	0.622000														84			20		0	0	1	0	0
OR1L1	26737	broad.mit.edu	37	9	125424320	125424320	+	Missense_Mutation	SNP	A	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr9:125424320A>G	uc022bmz.1	+	0	326	c.326A>G	c.(325-327)aAc>aGc	p.N109S		NM_001005236	NP_001005236	Q8NH94	OR1L1_HUMAN	Homo sapiens olfactory receptor, family 1, subfamily L, member 1 (OR1L1), mRNA.	159					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|kidney(2)|large_intestine(2)|lung(4)|ovary(1)|pancreas(1)|skin(5)|upper_aerodigestive_tract(1)	17						GCCTTTGGAAACACAGACAGT	0.448000														163			4		0	0	1	0	0
RFX1	5989	broad.mit.edu	37	19	14076447	14076447	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr19:14076447G>A	uc002mxv.3	-	14	2376	c.2104C>T	c.(2104-2106)Ccc>Tcc	p.P702S		NM_002918	NP_002909	P22670	RFX1_HUMAN	Homo sapiens regulatory factor X, 1 (influences HLA class II expression) (RFX1), mRNA.	702					immune response	nucleus	DNA binding|protein binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity			NS(1)|breast(1)|endometrium(3)|kidney(1)|large_intestine(2)|lung(8)|ovary(2)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)	21			OV - Ovarian serous cystadenocarcinoma(19;6.67e-23)			CTGGGGATGGGCCGCAGCACG	0.662000														36			30		0	0	1	0	0
LCN10	414332	broad.mit.edu	37	9	139636409	139636409	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr9:139636409C>T	uc004civ.3	-	1	240	c.181G>A	c.(181-183)Gac>Aac	p.D61N	LCN10_uc010nbq.3_Missense_Mutation_p.D61N|LCN10_uc011mee.2_Missense_Mutation_p.D61N|LCN10_uc011mef.2_Non-coding_Transcript|LCN10_uc011med.2_Splice_Site|LCN10_uc004ciw.3_Non-coding_Transcript|LCN10_uc022bpt.1_5'Flank	NM_001001712	NP_001001712	Q6JVE6	LCN10_HUMAN	Homo sapiens lipocalin 10 (LCN10), mRNA.	61					transport	extracellular region	binding			breast(2)|cervix(1)|large_intestine(1)	4	all_cancers(76;0.0882)|all_epithelial(76;0.228)	Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;5.32e-06)|Epithelial(140;7.83e-05)		TTCCTCTTGTCCCTGGCCGGC	0.647000														87			3		0	0	1	0	0
CLU	1191	broad.mit.edu	37	8	27468113	27468113	+	Silent	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr8:27468113C>T	uc003xfy.2	-	1	156	c.9G>A	c.(7-9)gcG>gcA	p.A3A	CLU_uc003xfw.2_5'UTR|CLU_uc003xfx.2_5'UTR|CLU_uc003xfz.2_5'UTR	NM_001831	NP_001822	P10909	CLUS_HUMAN	Homo sapiens clusterin (CLU), transcript variant 1, mRNA.	0					chaperone-mediated protein folding|complement activation, classical pathway|innate immune response|lipid metabolic process|negative regulation of apoptosis|negative regulation of protein homooligomerization|platelet activation|platelet degranulation|positive regulation of NF-kappaB transcription factor activity|positive regulation of proteasomal ubiquitin-dependent protein catabolic process|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|protein stabilization|response to misfolded protein|response to virus|reverse cholesterol transport	chromaffin granule|cytosol|endoplasmic reticulum|microsome|mitochondrial membrane|nucleus|perinuclear region of cytoplasm|platelet alpha granule lumen|spherical high-density lipoprotein particle	misfolded protein binding|ubiquitin protein ligase binding			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(8)|ovary(2)	21		Ovarian(32;2.61e-05)		UCEC - Uterine corpus endometrioid carcinoma (27;0.0204)|Colorectal(74;0.132)		AGTCTTTGCACGCCTCTGCAG	0.627000														86			3		0	0	1	0	0
ITGA5	3678	broad.mit.edu	37	12	54812840	54812840	+	Missense_Mutation	SNP	G	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr12:54812840G>T	uc001sga.3	-	0	211	c.143C>A	c.(142-144)gCc>gAc	p.A48D	ITGA5_uc010sow.1_Non-coding_Transcript|ITGA5_uc009znp.1_Non-coding_Transcript	NM_002205	NP_002196	P08648	ITA5_HUMAN	Homo sapiens integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5), mRNA.	48					angiogenesis|axon guidance|blood coagulation|integrin-mediated signaling pathway|interspecies interaction between organisms|leukocyte migration|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of vascular endothelial growth factor receptor signaling pathway|wound healing, spreading of epidermal cells	alphav-beta3 integrin-vitronectin complex|integrin complex|ruffle	platelet-derived growth factor receptor binding|receptor activity|vascular endothelial growth factor receptor 2 binding			NS(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(10)|lung(11)|ovary(2)|prostate(1)|upper_aerodigestive_tract(2)	34						TACTGCTGGGGCCTCCGCGTC	0.706000														135			9		2.17888e-05	2.17888e-05	1	1	0
BSN	8927	broad.mit.edu	37	3	49691694	49691694	+	Missense_Mutation	SNP	A	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr3:49691694A>T	uc003cxe.4	+	4	4819	c.4705A>T	c.(4705-4707)Acc>Tcc	p.T1569S		NM_003458	NP_003449	Q9UPA5	BSN_HUMAN	Homo sapiens bassoon (presynaptic cytomatrix protein) (BSN), mRNA.	1569					synaptic transmission	cell junction|cytoplasm|cytoskeleton|nucleus|synaptosome	metal ion binding			breast(8)|central_nervous_system(2)|cervix(2)|endometrium(16)|kidney(3)|large_intestine(17)|lung(37)|ovary(7)|pancreas(1)|prostate(4)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	106				BRCA - Breast invasive adenocarcinoma(193;6.66e-05)|KIRC - Kidney renal clear cell carcinoma(197;0.0032)|Kidney(197;0.00336)		CTCCAGCCAGACCAGGATGGT	0.607000														34			34		0	0	1	0	0
MYO1F	4542	broad.mit.edu	37	19	8615207	8615207	+	Missense_Mutation	SNP	T	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr19:8615207T>A	uc002mkg.3	-	9	1076	c.938A>T	c.(937-939)gAc>gTc	p.D313V		NM_012335	NP_036467	O00160	MYO1F_HUMAN	Homo sapiens myosin IF (MYO1F), mRNA.	313	Myosin head-like.					unconventional myosin complex	ATP binding|actin binding|calmodulin binding|motor activity			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(6)|large_intestine(7)|lung(13)|ovary(3)|prostate(3)|skin(3)|urinary_tract(1)	42						TCGCCCGCTGTCAATGCCCAG	0.627000														36			32		0	0	1	0	0
HSPG2	3339	broad.mit.edu	37	1	22207292	22207292	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr1:22207292G>A	uc009vqd.3	-	14	1898	c.1858C>T	c.(1858-1860)Cgc>Tgc	p.R620C	HSPG2_uc001bfj.3_Missense_Mutation_p.R619C	NM_005529	NP_005520	P98160	PGBM_HUMAN	Homo sapiens heparan sulfate proteoglycan 2 (HSPG2), mRNA.	619	Laminin IV type A 1.				angiogenesis|cell adhesion|lipid metabolic process|lipoprotein metabolic process	basement membrane|extracellular space|plasma membrane	protein C-terminus binding			breast(6)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(9)|large_intestine(15)|liver(1)|lung(44)|ovary(10)|pancreas(1)|prostate(10)|skin(9)|upper_aerodigestive_tract(3)|urinary_tract(3)	127		Colorectal(325;3.46e-05)|all_lung(284;7.93e-05)|Lung NSC(340;8.71e-05)|Renal(390;0.000219)|Breast(348;0.00222)|Ovarian(437;0.00308)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0498)|OV - Ovarian serous cystadenocarcinoma(117;1.14e-26)|Colorectal(126;4.18e-07)|COAD - Colon adenocarcinoma(152;1.82e-05)|GBM - Glioblastoma multiforme(114;3.13e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000756)|STAD - Stomach adenocarcinoma(196;0.00656)|KIRC - Kidney renal clear cell carcinoma(1967;0.00942)|READ - Rectum adenocarcinoma(331;0.0721)|Lung(427;0.223)	Becaplermin(DB00102)|Palifermin(DB00039)	AACTCGTAGCGCACGTTGTAA	0.657000														2			27		0	0	1	0	0
LTN1	26046	broad.mit.edu	37	21	30331996	30331996	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr21:30331996C>T	uc002ymr.2	-	12	2528	c.2515G>A	c.(2515-2517)Gtt>Att	p.V839I		NM_015565	NP_056380	O94822	LTN1_HUMAN	Homo sapiens listerin E3 ubiquitin protein ligase 1 (LTN1), mRNA.	793							ligase activity|zinc ion binding			NS(1)|central_nervous_system(1)|endometrium(4)|kidney(5)|large_intestine(12)|lung(19)|ovary(5)|pancreas(1)|prostate(2)|skin(6)|stomach(2)|upper_aerodigestive_tract(2)	60						ATTCTTTCAACATATACGTCT	0.279000														5			40		0	0	1	0	0
HOMEZ	57594	broad.mit.edu	37	14	23745955	23745955	+	Missense_Mutation	SNP	T	C	C			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr14:23745955T>C	uc001wja.2	-	1	630	c.482A>G	c.(481-483)gAg>gGg	p.E161G	HOMEZ_uc001wjb.2_Missense_Mutation_p.E163G	NM_020834	NP_065885	Q8IX15	HOMEZ_HUMAN	Homo sapiens homeobox and leucine zipper encoding (HOMEZ), mRNA.	161	Pro-rich.					nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			endometrium(5)|lung(7)	12	all_cancers(95;5.54e-06)			GBM - Glioblastoma multiforme(265;0.00643)		ACCAACTTGCTCTGGAGCTGG	0.547000														110			4		0	0	1	0	0
GEM	2669	broad.mit.edu	37	8	95264412	95264412	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr8:95264412C>T	uc003ygi.3	-	3	572	c.448G>A	c.(448-450)Ggg>Agg	p.G150R	GEM_uc003ygj.3_Missense_Mutation_p.G150R	NM_181702	NP_859053	P55040	GEM_HUMAN	Homo sapiens GTP binding protein overexpressed in skeletal muscle (GEM), transcript variant 2, mRNA.	150					cell surface receptor linked signaling pathway|immune response|small GTPase mediated signal transduction	internal side of plasma membrane	GDP binding|GTP binding|GTPase activity|calmodulin binding|magnesium ion binding			endometrium(3)|kidney(1)|large_intestine(7)|lung(9)|prostate(1)|upper_aerodigestive_tract(1)	22	Breast(36;4.65e-06)	Myeloproliferative disorder(644;0.204)	BRCA - Breast invasive adenocarcinoma(8;0.00691)			TATGCGTCCCCGACCTGCATG	0.517000														29			31		0	0	1	0	0
TLE1	7088	broad.mit.edu	37	9	84199172	84199172	+	Missense_Mutation	SNP	T	C	C			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr9:84199172T>C	uc004alz.3	-	19	2725	c.2284A>G	c.(2284-2286)Aag>Gag	p.K762E	TLE1_uc004aly.3_Missense_Mutation_p.K752E|TLE1_uc011lsr.2_Missense_Mutation_p.K737E	NM_005077	NP_005068	Q04724	TLE1_HUMAN	Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), mRNA.	752					Wnt receptor signaling pathway|negative regulation of Wnt receptor signaling pathway|organ morphogenesis|transcription, DNA-dependent		transcription factor binding			NS(1)|endometrium(5)|kidney(2)|large_intestine(2)|lung(11)|ovary(1)|pancreas(1)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	29						ACTATGTACTTATCATCCACA	0.423000														129			3		0	0	1	0	0
GPBP1	65056	broad.mit.edu	37	5	56545266	56545266	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr5:56545266G>A	uc003jrk.4	+	7	913	c.856G>A	c.(856-858)Gac>Aac	p.D286N	GPBP1_uc003jrh.4_Missense_Mutation_p.D279N|GPBP1_uc003jri.4_Missense_Mutation_p.D108N|GPBP1_uc003jrj.4_Intron|GPBP1_uc021xyv.1_Missense_Mutation_p.D108N	NM_001127236	NP_001190175	Q86WP2	GPBP1_HUMAN	Homo sapiens GC-rich promoter binding protein 1 (GPBP1), transcript variant 2, mRNA.	279					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding			breast(2)|central_nervous_system(1)|cervix(2)|endometrium(2)|kidney(2)|large_intestine(3)|lung(4)|ovary(1)|skin(1)|urinary_tract(1)	19		Lung NSC(810;0.000861)|Prostate(74;0.0305)|Breast(144;0.222)		OV - Ovarian serous cystadenocarcinoma(10;7.64e-39)		TTCTCCTGTTGACAAACTTAA	0.363000														236			40		0	0	1	0	0
ASXL2	55252	broad.mit.edu	37	2	25966455	25966455	+	Silent	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr2:25966455C>T	uc002rgs.2	-	11	2972	c.2751G>A	c.(2749-2751)tcG>tcA	p.S917S	ASXL2_uc002rgt.1_Intron	NM_018263	NP_060733	Q76L83	ASXL2_HUMAN	Homo sapiens additional sex combs like 2 (Drosophila) (ASXL2), mRNA.	917					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	metal ion binding|protein binding			NS(1)|breast(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|lung(7)|pancreas(1)|prostate(4)|skin(3)|urinary_tract(3)	33	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					GCAAAGTGCTCGAGGGTGGAG	0.473000														77			3		0	0	1	0	0
SERPINB3	6317	broad.mit.edu	37	18	61323171	61323171	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr18:61323171G>A	uc002lji.3	-	7	1037	c.893C>T	c.(892-894)aCg>aTg	p.T298M	SERPINB3_uc002ljg.3_Intron|SERPINB3_uc010dqa.3_Missense_Mutation_p.T246M	NM_006919	NP_008850	P29508	SPB3_HUMAN	Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 3 (SERPINB3), mRNA.	298					regulation of proteolysis	cytoplasm|extracellular region	protein binding|serine-type endopeptidase inhibitor activity	p.T298M(2)|p.D297N(1)		breast(2)|central_nervous_system(1)|endometrium(4)|kidney(3)|large_intestine(4)|lung(14)|ovary(1)|skin(5)|upper_aerodigestive_tract(2)	36						GGTTCTCAACGTGTCCTTGAG	0.488000														103			51		0	0	1	0	0
CYP4F2	8529	broad.mit.edu	37	19	16000303	16000303	+	Missense_Mutation	SNP	A	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr19:16000303A>G	uc002nbs.1	-	6	898	c.848T>C	c.(847-849)gTt>gCt	p.V283A	CYP4F2_uc010xot.1_Missense_Mutation_p.V134A|CYP4F2_uc010xou.1_Missense_Mutation_p.V134A	NM_001082	NP_001073	P78329	CP4F2_HUMAN	Homo sapiens cytochrome P450, family 4, subfamily F, polypeptide 2 (CYP4F2), mRNA.	283					leukotriene metabolic process|long-chain fatty acid metabolic process|very long-chain fatty acid metabolic process|xenobiotic metabolic process	endoplasmic reticulum membrane|microsome	alkane 1-monooxygenase activity|electron carrier activity|heme binding|leukotriene-B4 20-monooxygenase activity|oxygen binding|protein binding			NS(2)|breast(1)|endometrium(6)|kidney(2)|large_intestine(9)|liver(1)|lung(18)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	46						GAAGTCATCAACACCCTGGCT	0.577000														163			4		0	0	1	0	0
TTLL1	25809	broad.mit.edu	37	22	43459837	43459837	+	Silent	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr22:43459837G>A	uc003bdi.3	-	6	970	c.729C>T	c.(727-729)gtC>gtT	p.V243V	TTLL1_uc010gzh.3_Silent_p.V243V|TTLL1_uc021wqt.1_Silent_p.V205V|TTLL1_uc003bdj.3_Silent_p.V129V	NM_012263	NP_036395	O95922	TTLL1_HUMAN	Homo sapiens tubulin tyrosine ligase-like family, member 1 (TTLL1), transcript variant 1, mRNA.	243	TTL.				protein polyglutamylation	cytoplasm|microtubule	ATP binding|tubulin-glutamic acid ligase activity|tubulin-tyrosine ligase activity			breast(3)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(7)|ovary(1)|skin(2)|stomach(1)	23		Ovarian(80;0.0694)		BRCA - Breast invasive adenocarcinoma(115;0.00461)		TCTGGATGGCGACGTTGGTGA	0.532000														93			3		0	0	1	0	0
SIN3A	25942	broad.mit.edu	37	15	75682085	75682085	+	Missense_Mutation	SNP	A	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr15:75682085A>G	uc002bai.3	-	15	3188	c.2929T>C	c.(2929-2931)Tca>Cca	p.S977P	SIN3A_uc002baj.3_Missense_Mutation_p.S977P|SIN3A_uc010uml.2_Missense_Mutation_p.S977P	NM_015477	NP_056292	Q96ST3	SIN3A_HUMAN	Homo sapiens SIN3 transcription regulator homolog A (yeast) (SIN3A), transcript variant 2, mRNA.	977					blood coagulation|cellular lipid metabolic process|negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	Sin3 complex|nucleolus	protein binding			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(16)|lung(15)|ovary(3)|prostate(2)|skin(5)|upper_aerodigestive_tract(2)	63						TCATACTGTGATGAGTCTATG	0.478000														129			4		0	0	1	0	0
MYL7	58498	broad.mit.edu	37	7	44179423	44179423	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr7:44179423C>T	uc003tkg.3	-	4	347	c.335G>A	c.(334-336)cGc>cAc	p.R112H		NM_021223	NP_067046	Q01449	MLRA_HUMAN	Homo sapiens myosin, light chain 7, regulatory (MYL7), mRNA.	112	EF-hand 2.				actin filament-based movement|smooth muscle contraction	A band|myosin complex	ATPase activity, coupled|calcium ion binding|microfilament motor activity			central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(4)|prostate(1)|skin(1)	12						GTCAAACATGCGGAAGGCACT	0.627000														86			3		0	0	1	0	0
EHD2	30846	broad.mit.edu	37	19	48220038	48220038	+	Missense_Mutation	SNP	G	A	A	rs34140460	byFrequency	TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr19:48220038G>A	uc002phj.4	+	1	419	c.169G>A	c.(169-171)Ggc>Agc	p.G57S	EHD2_uc010xyu.2_Intron	NM_014601	NP_055416	Q9NZN4	EHD2_HUMAN	Homo sapiens EH-domain containing 2 (EHD2), mRNA.	57			G -> S (in dbSNP:rs34140460).		blood coagulation|endocytic recycling	nucleus|plasma membrane|recycling endosome membrane	ATP binding|GTP binding|GTPase activity|calcium ion binding|nucleic acid binding			endometrium(3)|large_intestine(7)|lung(2)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(3)	19		all_cancers(25;6.74e-07)|all_lung(116;2.02e-05)|Lung NSC(112;3.77e-05)|all_epithelial(76;4.89e-05)|all_neural(266;0.0332)|Ovarian(192;0.086)		OV - Ovarian serous cystadenocarcinoma(262;0.000336)|all cancers(93;0.000415)|Epithelial(262;0.0132)|GBM - Glioblastoma multiforme(486;0.0537)		AGACTTCGACGGCAAGCCCAT	0.682000														75			4		0	0	1	0	0
TOX	9760	broad.mit.edu	37	8	60031454	60031454	+	Nonsense_Mutation	SNP	A	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr8:60031454A>T	uc003xtw.1	-	0	314	c.93T>A	c.(91-93)taT>taA	p.Y31*		NM_014729	NP_055544	O94900	TOX_HUMAN	Homo sapiens thymocyte selection-associated high mobility group box (TOX), mRNA.	31						nucleus	DNA binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(11)|lung(13)|prostate(1)|skin(2)|stomach(1)	33		all_cancers(86;0.165)|Myeloproliferative disorder(644;0.00452)|all_lung(136;0.036)|Lung NSC(129;0.0464)|all_epithelial(80;0.0607)				CCTTGTTGCAATAGTAGGGGT	0.632000														38			35		0	0	1	0	0
TUBB8	347688	broad.mit.edu	37	10	93637	93637	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr10:93637G>A	uc001ifi.2	-	3	695	c.695C>T	c.(694-696)aCc>aTc	p.T232I		NM_177987	NP_817124	Q3ZCM7	TBB8_HUMAN	Homo sapiens tubulin, beta 8 class VIII (TUBB8), transcript variant 1, mRNA.	232					microtubule-based movement|protein polymerization	cytoplasm|microtubule	GTP binding|GTPase activity|structural molecule activity	p.T232I(2)		NS(1)|cervix(1)|endometrium(4)|large_intestine(5)|lung(12)|ovary(2)|prostate(3)|skin(3)|stomach(1)	32		all_cancers(4;0.00131)|all_lung(4;0.000777)|Lung NSC(4;0.0043)|all_epithelial(10;0.0154)|Colorectal(49;0.235)		Epithelial(11;0.00341)|all cancers(11;0.00922)|OV - Ovarian serous cystadenocarcinoma(14;0.0508)|Lung(33;0.132)		CCCACTCATGGTAGCAGACAC	0.557000														20			3		0	0	1	0	0
KRT76	51350	broad.mit.edu	37	12	53169235	53169235	+	Missense_Mutation	SNP	T	C	C			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr12:53169235T>C	uc001sax.3	-	1	806	c.752A>G	c.(751-753)gAg>gGg	p.E251G		NM_015848	NP_056932	Q01546	K22O_HUMAN	Homo sapiens keratin 76 (KRT76), mRNA.	251	Coil 1B.|Rod.				cytoskeleton organization	keratin filament	structural molecule activity	p.G250V(1)		breast(1)|endometrium(2)|kidney(1)|large_intestine(5)|lung(10)|prostate(1)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	27						GTTCCCCCTCTCCCCTAGAAG	0.552000														82			5		0	0	1	0	0
EBF1	1879	broad.mit.edu	37	5	158526463	158526463	+	Silent	SNP	G	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr5:158526463G>T	uc010jip.3	-	0	326	c.24C>A	c.(22-24)atC>atA	p.I8I	EBF1_uc011ddw.2_5'Flank|EBF1_uc011ddx.2_Silent_p.I8I|EBF1_uc003lxl.4_Silent_p.I8I|AK123543_uc003lxm.1_5'Flank	NM_024007	NP_076870	Q9UH73	COE1_HUMAN	Homo sapiens early B-cell factor 1 (EBF1), mRNA.	8					multicellular organismal development	nucleus	DNA binding|metal ion binding		HMGA2/EBF1(2)	breast(3)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(7)|lung(18)|ovary(1)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)	42	Renal(175;0.00196)	Acute lymphoblastic leukemia(3;2.99e-06)|all_hematologic(3;0.000772)|Medulloblastoma(196;0.037)|all_neural(177;0.143)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			CACTCCGTTGGATGCTTTCCT	0.493000			T	HMGA2	lipoma									100			34		9.39024e-22	1.0061e-21	1	1	0
CLCN2	1181	broad.mit.edu	37	3	184075816	184075816	+	Missense_Mutation	SNP	C	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr3:184075816C>G	uc003foi.3	-	4	673	c.549G>C	c.(547-549)aaG>aaC	p.K183N	CLCN2_uc003foh.3_5'Flank|CLCN2_uc010hya.2_Missense_Mutation_p.K183N|CLCN2_uc011brl.2_Missense_Mutation_p.K183N|CLCN2_uc011brm.2_Missense_Mutation_p.K139N|CLCN2_uc011brn.1_Missense_Mutation_p.K183N	NM_004366	NP_004357	P51788	CLCN2_HUMAN	Homo sapiens chloride channel 2 (CLCN2), transcript variant 1, mRNA.	183						chloride channel complex	voltage-gated chloride channel activity			breast(2)|central_nervous_system(4)|endometrium(1)|kidney(3)|large_intestine(4)|lung(9)|ovary(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	27	all_cancers(143;6.66e-11)|Ovarian(172;0.0339)		Epithelial(37;2.22e-33)|OV - Ovarian serous cystadenocarcinoma(80;2.72e-22)		Lubiprostone(DB01046)	CTATAAAGGTCTTGAGTGTGA	0.562000														73			45		0	0	1	0	0
TIGIT	201633	broad.mit.edu	37	3	114018494	114018494	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr3:114018494G>A	uc003ebg.2	+	2	1197	c.442G>A	c.(442-444)Gcg>Acg	p.A148T		NM_173799	NP_776160	Q495A1	TIGIT_HUMAN	Homo sapiens T cell immunoreceptor with Ig and ITIM domains (TIGIT), mRNA.	148					negative regulation of T cell activation|negative regulation of interleukin-12 production|positive regulation of interleukin-10 production	cell surface|integral to membrane|plasma membrane	protein binding	p.A147A(1)		breast(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|large_intestine(4)|lung(7)|prostate(1)	17						AGCCATGGCCGCGACGCTGGT	0.582000														47			10		0	0	1	0	0
SACS	26278	broad.mit.edu	37	13	23915268	23915268	+	Missense_Mutation	SNP	T	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr13:23915268T>G	uc001uon.2	-	9	3336	c.2747A>C	c.(2746-2748)aAa>aCa	p.K916T	SACS_uc001uoo.2_Missense_Mutation_p.K769T|SACS_uc001uop.1_Intron|SACS_uc001uoq.1_Intron	NM_014363	NP_055178	Q9NZJ4	SACS_HUMAN	Homo sapiens spastic ataxia of Charlevoix-Saguenay (sacsin) (SACS), mRNA.	916					cell death|negative regulation of inclusion body assembly|protein folding	axon|cell body fiber|dendrite|mitochondrion|nucleus	ATP binding|Hsp70 protein binding|chaperone binding|proteasome binding			NS(1)|biliary_tract(1)|breast(3)|central_nervous_system(2)|endometrium(22)|haematopoietic_and_lymphoid_tissue(1)|kidney(15)|large_intestine(54)|lung(49)|ovary(7)|pancreas(1)|prostate(4)|skin(10)|stomach(2)|upper_aerodigestive_tract(6)|urinary_tract(11)	189		all_cancers(29;1.51e-22)|all_epithelial(30;7.82e-19)|all_lung(29;4.71e-18)|Lung SC(185;0.0225)|Breast(139;0.128)		all cancers(112;0.00197)|Epithelial(112;0.00854)|OV - Ovarian serous cystadenocarcinoma(117;0.0298)|Lung(94;0.189)		TCTTTTCTCTTTCTCACTGCT	0.363000														5			37		0	0	1	0	0
PPP1R11	6992	broad.mit.edu	37	6	30035207	30035207	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr6:30035207G>A	uc003npb.3	+	0	276	c.20G>A	c.(19-21)gGg>gAg	p.G7E	PPP1R11_uc010jrw.3_Non-coding_Transcript|PPP1R11_uc003npc.3_Non-coding_Transcript	NM_021959	NP_068778	O60927	PP1RB_HUMAN	Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit 11 (PPP1R11), mRNA.	7						soluble fraction	protein binding|protein phosphatase inhibitor activity			lung(2)|ovary(1)|prostate(1)|skin(2)	6						GCAGGGGCTGGGCTGAGCGAG	0.607000														50			3		0	0	1	0	0
MGC70870	403340	broad.mit.edu	37	GL000205.1	117585	117585	+	RNA	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chrGL000205.1:117585C>T	uc002kgk.4	+	0		c.963C>T								Homo sapiens C-terminal binding protein 2 pseudogene (MGC70870), non-coding RNA.																		AGACAGCCGACTCCACCACCG	0.617000														24			4		0	0	1	0	0
BCAR1	9564	broad.mit.edu	37	16	75270827	75270827	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr16:75270827C>T	uc002fdv.3	-	3	1011	c.865G>A	c.(865-867)Gtg>Atg	p.V289M	BCAR1_uc002fdt.3_5'Flank|BCAR1_uc002fdu.3_Missense_Mutation_p.V79M|BCAR1_uc010vna.2_Missense_Mutation_p.V287M|BCAR1_uc010cgu.3_Missense_Mutation_p.V289M|BCAR1_uc010vnb.2_Missense_Mutation_p.V335M|BCAR1_uc002fdw.3_Missense_Mutation_p.V289M|BCAR1_uc010vnc.2_Missense_Mutation_p.V141M|BCAR1_uc010vnd.2_Missense_Mutation_p.V307M|BCAR1_uc002fdx.3_Missense_Mutation_p.V307M	NM_014567	NP_055382	P56945	BCAR1_HUMAN	Homo sapiens breast cancer anti-estrogen resistance 1 (BCAR1), transcript variant 6, mRNA.	289	Substrate for kinases (By similarity).				B cell receptor signaling pathway|G-protein coupled receptor protein signaling pathway|T cell receptor signaling pathway|actin filament organization|blood coagulation|cell adhesion|cell division|cell migration|cell proliferation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|integrin-mediated signaling pathway|nerve growth factor receptor signaling pathway|platelet-derived growth factor receptor signaling pathway|positive regulation of cell migration|regulation of apoptosis|regulation of cell growth	cytosol|focal adhesion|membrane fraction|ruffle	SH3 domain binding|protein kinase binding|protein phosphatase binding|signal transducer activity			breast(2)|central_nervous_system(5)|endometrium(1)|kidney(6)|large_intestine(1)|liver(1)|lung(13)|ovary(1)|prostate(3)|upper_aerodigestive_tract(2)	35				BRCA - Breast invasive adenocarcinoma(221;0.169)		CTGGGGGGCACGTCATACACC	0.632000														41			3		0	0	1	0	0
GPBP1	65056	broad.mit.edu	37	5	56545374	56545374	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr5:56545374G>A	uc003jrk.4	+	7	1021	c.964G>A	c.(964-966)Gaa>Aaa	p.E322K	GPBP1_uc003jrh.4_Missense_Mutation_p.E315K|GPBP1_uc003jri.4_Missense_Mutation_p.E144K|GPBP1_uc003jrj.4_Missense_Mutation_p.E307K|GPBP1_uc021xyv.1_Missense_Mutation_p.E144K	NM_001127236	NP_001190175	Q86WP2	GPBP1_HUMAN	Homo sapiens GC-rich promoter binding protein 1 (GPBP1), transcript variant 2, mRNA.	315					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding	p.S322L(1)		breast(2)|central_nervous_system(1)|cervix(2)|endometrium(2)|kidney(2)|large_intestine(3)|lung(4)|ovary(1)|skin(1)|urinary_tract(1)	19		Lung NSC(810;0.000861)|Prostate(74;0.0305)|Breast(144;0.222)		OV - Ovarian serous cystadenocarcinoma(10;7.64e-39)		AGAGGAACATGAAGATGAAAG	0.373000														203			42		0	0	1	0	0
CACNA2D1	781	broad.mit.edu	37	7	81641523	81641523	+	Missense_Mutation	SNP	C	T	T			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr7:81641523C>T	uc003uhr.1	-	14	1565	c.1309G>A	c.(1309-1311)Gca>Aca	p.A437T	AK055932_uc003uhs.1_Intron	NM_000722	NP_000713	P54289	CA2D1_HUMAN	Homo sapiens calcium channel, voltage-dependent, alpha 2/delta subunit 1 (CACNA2D1), mRNA.	437						voltage-gated calcium channel complex	metal ion binding			breast(2)|cervix(1)|endometrium(1)|kidney(2)|large_intestine(15)|liver(1)|lung(42)|ovary(6)|pancreas(1)|prostate(2)|skin(4)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	81					Felodipine(DB01023)|Gabapentin(DB00996)|Ibutilide(DB00308)|Isradipine(DB00270)|Magnesium Sulfate(DB00653)|Nifedipine(DB01115)	TTGTCTCCTGCTAAAACCATT	0.363000														125			27		0	0	1	0	0
DDX55	57696	broad.mit.edu	37	12	124092052	124092052	+	Missense_Mutation	SNP	A	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr12:124092052A>G	uc001ufi.3	+	3	344	c.320A>G	c.(319-321)aAg>aGg	p.K107R	DDX55_uc001ufh.3_5'UTR|DDX55_uc001ufj.1_Intron|DDX55_uc001ufk.3_5'UTR	NM_020936	NP_065987	Q8NHQ9	DDX55_HUMAN	Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 (DDX55), mRNA.	107	Helicase ATP-binding.						ATP binding|ATP-dependent helicase activity|RNA binding			autonomic_ganglia(1)|breast(1)|endometrium(1)|large_intestine(3)|liver(1)|lung(4)|ovary(1)|prostate(1)|skin(1)	14	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.000142)|Epithelial(86;0.000637)|all cancers(50;0.00772)		CATTTCACGAAGCACTTCCCC	0.493000														337			6		0	0	1	0	0
TBC1D15	64786	broad.mit.edu	37	12	72314554	72314554	+	Missense_Mutation	SNP	T	C	C			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr12:72314554T>C	uc001swu.3	+	15	1769	c.1694T>C	c.(1693-1695)cTc>cCc	p.L565P	TBC1D15_uc001sww.3_Missense_Mutation_p.L319P|TBC1D15_uc010stt.2_Missense_Mutation_p.L556P|TBC1D15_uc001swv.3_Missense_Mutation_p.L548P	NM_022771	NP_073608	Q8TC07	TBC15_HUMAN	Homo sapiens TBC1 domain family, member 15 (TBC1D15), transcript variant 1, mRNA.	565							Rab GTPase activator activity|protein binding			NS(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(8)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	24						CATCTTCTTCTCTGTTGTGCT	0.323000														87			4		0	0	1	0	0
NBEAL2	23218	broad.mit.edu	37	3	47041771	47041771	+	Silent	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr3:47041771G>A	uc003cqp.3	+	26	4361	c.4182G>A	c.(4180-4182)ggG>ggA	p.G1394G	NBEAL2_uc010hjm.2_Silent_p.G771G|NBEAL2_uc010hjn.2_5'Flank	NM_015175	NP_055990	Q6ZNJ1	NBEL2_HUMAN	Homo sapiens neurobeachin-like 2 (NBEAL2), mRNA.	1394							binding	p.Q1393R(1)		NS(1)|breast(1)|central_nervous_system(3)|cervix(2)|endometrium(8)|kidney(5)|large_intestine(9)|lung(9)|ovary(4)|pancreas(1)|prostate(3)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	51		Acute lymphoblastic leukemia(5;0.0534)		BRCA - Breast invasive adenocarcinoma(193;0.0012)|KIRC - Kidney renal clear cell carcinoma(197;0.00575)|Kidney(197;0.00656)		CACTGGATGGGCCGCGGCCCT	0.642000														57			65		0	0	1	0	0
ABL1	25	broad.mit.edu	37	9	133748274	133748274	+	Missense_Mutation	SNP	A	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr9:133748274A>G	uc004bzw.3	+	5	938	c.935A>G	c.(934-936)tAt>tGt	p.Y312C	ABL1_uc004bzv.3_Missense_Mutation_p.Y331C	NM_005157	NP_005148	P00519	ABL1_HUMAN	Homo sapiens c-abl oncogene 1, non-receptor tyrosine kinase (ABL1), transcript variant a, mRNA.	312	Protein kinase.				DNA damage induced protein phosphorylation|DNA damage response, signal transduction resulting in induction of apoptosis|actin cytoskeleton organization|axon guidance|blood coagulation|cell adhesion|mismatch repair|muscle cell differentiation|negative regulation of protein serine/threonine kinase activity|peptidyl-tyrosine phosphorylation|positive regulation of muscle cell differentiation|positive regulation of oxidoreductase activity|regulation of transcription involved in S phase of mitotic cell cycle	cytoskeleton|cytosol|nuclear membrane|nucleolus|perinuclear region of cytoplasm	ATP binding|DNA binding|SH3 domain binding|magnesium ion binding|manganese ion binding|mitogen-activated protein kinase binding|non-membrane spanning protein tyrosine kinase activity|proline-rich region binding|protein C-terminus binding	p.F311I(9)|p.F311L(4)		breast(3)|central_nervous_system(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1149)|kidney(3)|large_intestine(7)|lung(15)|ovary(1)|skin(4)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	1195		all_hematologic(13;0.0361)|Acute lymphoblastic leukemia(5;0.0543)|Myeloproliferative disorder(178;0.204)		OV - Ovarian serous cystadenocarcinoma(145;5.4e-05)	Adenosine triphosphate(DB00171)|Dasatinib(DB01254)|Imatinib(DB00619)	CCCCCGTTCTATATCATCACT	0.552000			"""T, Mis"""	"""BCR, ETV6, NUP214"""	"""CML, ALL, T-ALL"""									99			7		0	0	1	0	0
AY455283	0	broad.mit.edu	37	12	8048219	8048219	+	Missense_Mutation	SNP	A	G	G			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr12:8048219A>G	uc001qtp.1	+	1	207	c.127A>G	c.(127-129)Act>Gct	p.T43A						SubName: Full=Uncharacterized protein;																		GAAGACCAGAACTGTGTTCTC	0.463000														47			34		0	0	1	0	0
SYT7	9066	broad.mit.edu	37	11	61291299	61291299	+	Splice_Site	SNP	C	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr11:61291299C>A	uc001nrv.3	-	7	959	c.907_splice	c.e7+1	p.D303_splice	SYT7_uc009ynr.3_Splice_Site_p.D378_splice	NM_004200	NP_004191	O43581	SYT7_HUMAN	Homo sapiens synaptotagmin VII (SYT7), transcript variant 2, mRNA.	303	C2 2.					cell junction|integral to membrane|synaptic vesicle membrane	transporter activity			kidney(2)|large_intestine(3)|lung(4)|ovary(3)|pancreas(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	15						AGCCCCGTACCTGATGTGCCC	0.592000														60			40		1.15505e-17	1.20877e-17	1	1	0
MAP1B	4131	broad.mit.edu	37	5	71493836	71493836	+	Missense_Mutation	SNP	G	A	A			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr5:71493836G>A	uc003kbw.4	+	4	4895	c.4654G>A	c.(4654-4656)Gtg>Atg	p.V1552M	MAP1B_uc010iyw.1_Missense_Mutation_p.V1569M|MAP1B_uc010iyx.1_Missense_Mutation_p.V1426M|MAP1B_uc010iyy.1_Missense_Mutation_p.V1426M	NM_005909	NP_005900	P46821	MAP1B_HUMAN	Homo sapiens microtubule-associated protein 1B (MAP1B), mRNA.	1552						microtubule|microtubule associated complex	structural molecule activity			NS(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(42)|liver(1)|lung(28)|ovary(1)|pancreas(1)|prostate(3)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	104		Lung NSC(167;0.00202)|Ovarian(174;0.0175)|Prostate(461;0.142)|Breast(144;0.198)		OV - Ovarian serous cystadenocarcinoma(47;7.99e-54)		TGTGGCCTCAGTGTCCACAGC	0.517000														53			77		0	0	1	0	0
ODF2L	57489	broad.mit.edu	37	1	86826142	86826142	+	Frame_Shift_Del	DEL	T	-	-			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr1:86826142delT	uc001dll.2	-	11	1583	c.1221delA	c.(1219-1221)aaafs	p.K407fs	ODF2L_uc001dlp.3_Frame_Shift_Del_p.K407fs|ODF2L_uc010osg.2_Frame_Shift_Del_p.K378fs|ODF2L_uc001dlm.2_Frame_Shift_Del_p.K378fs|ODF2L_uc021opg.1_Frame_Shift_Del_p.K247fs|ODF2L_uc001dlq.2_Frame_Shift_Del_p.K208fs|ODF2L_uc009wcr.2_Frame_Shift_Del_p.K247fs	NM_001007022	NP_001007023	Q9ULJ1	ODF2L_HUMAN	Homo sapiens outer dense fiber of sperm tails 2-like (ODF2L), transcript variant 2, mRNA.	407						centrosome		p.K378fs*22(2)		endometrium(2)|kidney(2)|large_intestine(10)|lung(6)|ovary(1)|pancreas(1)|skin(1)|stomach(1)	24				all cancers(265;0.0313)|Epithelial(280;0.0611)		GGGTTTTCTGTTTTTTTTCTA	0.289													---	154	---	---	7	---					
TNK2	10188	broad.mit.edu	37	3	195594314	195594314	+	Frame_Shift_Del	DEL	G	-	-			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr3:195594314delG	uc003fvu.1	-	11	3353	c.2810delC	c.(2809-2811)ccgfs	p.P937fs	TNK2_uc003fvq.1_Frame_Shift_Del_p.P344fs|TNK2_uc003fvr.1_Frame_Shift_Del_p.P462fs|TNK2_uc003fvs.1_Frame_Shift_Del_p.P969fs|TNK2_uc003fvt.1_Frame_Shift_Del_p.P1015fs|TNK2_uc010hzw.1_Non-coding_Transcript	NM_005781	NP_005772	Q07912	ACK1_HUMAN	Homo sapiens tyrosine kinase, non-receptor, 2 (TNK2), transcript variant 1, mRNA.	937	Pro-rich.			Missing (in Ref. 4; AAH08884).	positive regulation of peptidyl-tyrosine phosphorylation|protein ubiquitination|small GTPase mediated signal transduction	adherens junction|cytoplasmic vesicle membrane|endosome|nucleus	ATP binding|GTPase inhibitor activity|metal ion binding|non-membrane spanning protein tyrosine kinase activity|protein binding			central_nervous_system(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(1)|lung(11)|ovary(3)|prostate(4)|skin(2)|stomach(1)|urinary_tract(1)	29	all_cancers(143;6.48e-09)|Ovarian(172;0.0634)|Breast(254;0.206)	Lung NSC(153;0.191)	Epithelial(36;3.72e-24)|all cancers(36;1.46e-22)|OV - Ovarian serous cystadenocarcinoma(49;8.3e-19)|Lung(62;4.65e-05)|LUSC - Lung squamous cell carcinoma(58;5.31e-05)	GBM - Glioblastoma multiforme(46;0.000757)	Adenosine triphosphate(DB00171)	AGTGGCCCTCGGGGGTGGTGG	0.716													---	4	---	---	2	---					
KIAA0947	23379	broad.mit.edu	37	5	5463283	5463284	+	Frame_Shift_Ins	INS	-	TA	TA			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr5:5463283_5463284insTA	uc003jdm.4	+	12	4058_4059	c.3836_3837insTA	c.(3835-3837)ggtfs	p.G1279fs		NM_015325	NP_056140	Q9Y2F5	K0947_HUMAN	Homo sapiens KIAA0947 (KIAA0947), mRNA.	1279										breast(2)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(5)|lung(14)|ovary(1)|prostate(4)|upper_aerodigestive_tract(1)	35						GATTGCAATGGTAAAGATACTG	0.371													---	30	---	---	21	---					
DTWD1	56986	broad.mit.edu	37	15	49935536	49935536	+	Frame_Shift_Del	DEL	C	-	-			TCGA-KM-8443-01A-11D-2310-10	TCGA-KM-8443-10A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c00de7a0-0b09-4e07-988c-ef2a7f8e932a	982dbbf8-fdf8-4653-91ed-2e857e1a7708	g.chr15:49935536delC	uc001zxq.3	+	5	953	c.676delC	c.(676-678)caafs	p.Q226fs	DTWD1_uc001zxs.3_Frame_Shift_Del_p.Q226fs|DTWD1_uc001zxr.3_Frame_Shift_Del_p.Q139fs	NM_020234	NP_064619	Q8N5C7	DTWD1_HUMAN	Homo sapiens DTW domain containing 1 (DTWD1), transcript variant 1, mRNA.	226										endometrium(1)|large_intestine(4)|lung(2)|ovary(1)|upper_aerodigestive_tract(1)	9		all_lung(180;0.0384)		all cancers(107;3.27e-08)|GBM - Glioblastoma multiforme(94;7.6e-05)		AGGGTTGTTACAAGTTGAGTT	0.299													---	102	---	---	8	---					
