Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
OR13C2	392376	broad.mit.edu	37	9	107367862	107367862	+	Missense_Mutation	SNP	C	T	T			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr9:107367862C>T	uc011lvq.2	-	0	47	c.47G>A	c.(46-48)gGa>gAa	p.G16E		NM_001004481	NP_001004481	Q8NGS9	O13C2_HUMAN	Homo sapiens olfactory receptor, family 13, subfamily C, member 2 (OR13C2), mRNA.	16					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			cervix(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(10)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	22						ACCAGAAAGTCCCTTCAGAAA	0.373000														180			17		0	0	1	0	0
BRCC3	79184	broad.mit.edu	37	X	154344462	154344462	+	Splice_Site	SNP	A	T	T			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chrX:154344462A>T	uc004fna.3	+	9	863	c.755_splice	c.e9+1	p.S252_splice	BRCC3_uc004fnb.3_Splice_Site_p.S227_splice|BRCC3_uc011mzy.2_Splice_Site_p.S228_splice	NM_024332	NP_077308	P46736	BRCC3_HUMAN	Homo sapiens BRCA1/BRCA2-containing complex, subunit 3 (BRCC3), transcript variant 1, mRNA.	252					G2/M transition DNA damage checkpoint|double-strand break repair|histone H2A K63-linked deubiquitination|positive regulation of DNA repair|response to X-ray	BRCA1-A complex|BRISC complex|nuclear ubiquitin ligase complex	enzyme regulator activity|metal ion binding|metallopeptidase activity|polyubiquitin binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(1)|lung(7)|ovary(1)|pancreas(1)|skin(1)	22	all_cancers(53;1.86e-17)|all_epithelial(53;2.71e-11)|all_lung(58;1.84e-07)|Lung NSC(58;5.62e-07)|all_hematologic(71;2.45e-06)|Acute lymphoblastic leukemia(192;6.56e-05)|Breast(217;0.176)|Renal(33;0.214)					GAGGATCCACAGGTAGAGACc	0.502000														113			3		0	0	1	0	0
WASH3P	374666	broad.mit.edu	37	15	102515344	102515344	+	Missense_Mutation	SNP	A	C	C	rs141089280	by1000genomes	TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr15:102515344A>C	uc002cdi.3	+	8	1988	c.568A>C	c.(568-570)Aag>Cag	p.K190Q	WASH3P_uc010bpo.3_Non-coding_Transcript|WASH3P_uc002cdq.3_Non-coding_Transcript|WASH3P_uc002cdr.3_Non-coding_Transcript					Homo sapiens WAS protein family homolog 3 pseudogene (WASH3P), non-coding RNA.											central_nervous_system(1)|endometrium(6)|kidney(11)|prostate(5)|stomach(1)|urinary_tract(1)	25						GCTGGAGAAGAAGCAGCAGAA	0.662000														18			6		0	0	1	0	0
ADHFE1	137872	broad.mit.edu	37	8	67357454	67357454	+	Splice_Site	SNP	T	G	G			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr8:67357454T>G	uc003xwb.4	+	6	388	c.354_splice	c.e6-1	p.S118_splice	ADHFE1_uc003xwd.4_Splice_Site|ADHFE1_uc003xwc.4_Splice_Site_p.S70_splice|ADHFE1_uc003xwe.4_Splice_Site|ADHFE1_uc003xwf.4_Intron|ADHFE1_uc011les.2_Splice_Site_p.S48_splice|ADHFE1_uc011leq.1_Intron|ADHFE1_uc011ler.1_Intron	NM_144650	NP_653251	Q8IWW8	HOT_HUMAN	Homo sapiens alcohol dehydrogenase, iron containing, 1 (ADHFE1), nuclear gene encoding mitochondrial protein, mRNA.	118					2-oxoglutarate metabolic process|molecular hydrogen transport	mitochondrial matrix	hydroxyacid-oxoacid transhydrogenase activity|metal ion binding			breast(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(8)|lung(10)|ovary(1)|pancreas(1)|skin(2)|urinary_tract(2)	29		Lung NSC(129;0.197)	Epithelial(68;0.0321)|all cancers(69;0.0751)|BRCA - Breast invasive adenocarcinoma(89;0.0855)|OV - Ovarian serous cystadenocarcinoma(28;0.226)			TTCTCCAAGCTTCATGGAAGC	0.403000														44			31		0	0	1	0	0
RRN3P3	100131998	broad.mit.edu	37	16	22444123	22444123	+	RNA	SNP	G	A	A			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr16:22444123G>A	uc010vbu.1	-	3		c.1060C>T			RRN3P3_uc002dkp.2_Non-coding_Transcript					Homo sapiens RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 3 (RRN3P3), non-coding RNA.																		ATCACTATCCGCTCAAAATTC	0.333000														94			4		0	0	1	0	0
ZNF224	7767	broad.mit.edu	37	19	44611929	44611929	+	Missense_Mutation	SNP	C	T	T			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr19:44611929C>T	uc002oyh.2	+	5	1933	c.1616C>T	c.(1615-1617)cCa>cTa	p.P539L	LOC100379224_uc002oyi.3_Non-coding_Transcript	NM_013398	NP_037530	Q9NZL3	ZN224_HUMAN	Homo sapiens zinc finger protein 224 (ZNF224), mRNA.	539					negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	transcriptional repressor complex	DNA binding|protein binding|zinc ion binding	p.R538K(1)		NS(1)|breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(5)|lung(2)|ovary(2)|prostate(1)|stomach(2)|urinary_tract(1)	19		Prostate(69;0.0435)				GGAGAGAGACCATACAATTGT	0.428000														119			4		0	0	1	0	0
CXorf48	54967	broad.mit.edu	37	X	134294442	134294442	+	Silent	SNP	G	A	A			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chrX:134294442G>A	uc004eyk.1	-	2	974	c.318C>T	c.(316-318)ccC>ccT	p.P106P	CXorf48_uc004eyl.1_Silent_p.P106P	NM_001031705	NP_001026875	Q8WUE5	CX048_HUMAN	Homo sapiens chromosome X open reading frame 48 (CXorf48), transcript variant 1, mRNA.	106										endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|lung(3)	5	Acute lymphoblastic leukemia(192;0.000127)					CTGAGTCTGAGGGTCCAGCAC	0.328000														314			5		0	0	1	0	0
ATP6V1A	523	broad.mit.edu	37	3	113522467	113522467	+	Missense_Mutation	SNP	T	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr3:113522467T>C	uc003eao.3	+	12	1640	c.1532T>C	c.(1531-1533)gTa>gCa	p.V511A	ATP6V1A_uc011bik.2_Missense_Mutation_p.V478A	NM_001690	NP_001681	P38606	VATA_HUMAN	Homo sapiens ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A (ATP6V1A), mRNA.	511					ATP hydrolysis coupled proton transport|cellular iron ion homeostasis|insulin receptor signaling pathway|transferrin transport	cytosol|integral to plasma membrane|proton-transporting V-type ATPase, V1 domain	ATP binding|hydrogen ion transporting ATP synthase activity, rotational mechanism|proton-transporting ATPase activity, rotational mechanism			breast(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(17)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	34						ACTCTGGAGGTAGCAAAACTT	0.308000														194			4		0	0	1	0	0
abParts	0	broad.mit.edu	37	14	106349982	106349982	+	RNA	SNP	T	C	C	rs61993612		TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr14:106349982T>C	uc021ser.1	-	3929		c.58668A>G								Parts of antibodies, mostly variable regions.																		CTGGGACGGGTCTCTGGTCAG	0.682000														68			10		0	0	1	0	0
LPHN3	23284	broad.mit.edu	37	4	62598528	62598528	+	Missense_Mutation	SNP	T	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr4:62598528T>C	uc010ihh.3	+	4	624	c.451T>C	c.(451-453)Tcc>Ccc	p.S151P	LPHN3_uc003hcq.4_Missense_Mutation_p.S151P|LPHN3_uc010ihg.1_Missense_Mutation_p.S219P|LPHN3_uc003hcs.1_5'UTR	NM_015236	NP_056051	Q9HAR2	LPHN3_HUMAN	Homo sapiens latrophilin 3 (LPHN3), mRNA.	151	Olfactomedin-like.				neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity|sugar binding			breast(5)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(5)|kidney(4)|large_intestine(21)|lung(73)|ovary(1)|pancreas(1)|prostate(6)|upper_aerodigestive_tract(1)	125						TTTGTTTGAGTCCGACCACCA	0.408000														68			5		0	0	1	0	0
GOLGA6L6	727832	broad.mit.edu	37	15	20740040	20740040	+	Missense_Mutation	SNP	A	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr15:20740040A>C	uc001ytk.2	-	7	1801	c.1710T>G	c.(1708-1710)gaT>gaG	p.D570E	DQ594309_uc010tzb.1_5'Flank	NM_001145004	NP_001138476	A8MZA4	GG6L6_HUMAN	Homo sapiens golgin A6 family-like 6 (GOLGA6L6), mRNA.	570	Gln-rich.|Glu-rich.							p.D570E(4)		NS(3)|endometrium(4)|kidney(1)|skin(3)	11						tccacatcttatcctcctgct	0.562000														98			12		0	0	1	0	0
DSCAM	1826	broad.mit.edu	37	21	41384994	41384994	+	Silent	SNP	G	A	A			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr21:41384994G>A	uc002yyq.1	-	32	6458	c.6006C>T	c.(6004-6006)aaC>aaT	p.N2002N	DSCAM_uc002yyr.1_Non-coding_Transcript	NM_001389	NP_001380	O60469	DSCAM_HUMAN	Homo sapiens Down syndrome cell adhesion molecule (DSCAM), transcript variant 1, mRNA.	2002				HRPGDLIHLPPYLRMDFLLNRGGPGTSRDLSLGQACLEPQK SRTLKRPTVLEPIPMEAASSASSTREGQSWQPGAVATLPQR EGAELGQAAKMSSSQESLLDSRGHLKGNNPYAKSYTLV -> IGQVTSYICLHTLEWTFC (in Ref. 1; AAC17966).	cell adhesion|dendrite self-avoidance|negative regulation of cell adhesion|positive regulation of axon extension involved in axon guidance|positive regulation of phosphorylation	axon|extracellular region|growth cone|integral to plasma membrane|membrane fraction	protein binding			NS(2)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(22)|haematopoietic_and_lymphoid_tissue(4)|kidney(6)|large_intestine(22)|lung(47)|ovary(7)|pancreas(2)|prostate(3)|skin(14)|upper_aerodigestive_tract(6)|urinary_tract(4)	142		all_cancers(19;0.186)|Prostate(19;1.15e-05)|all_epithelial(19;0.0103)				CGTAAGGATTGTTTCCTTTCA	0.463000														101			5		0	0	1	0	0
AMPD1	270	broad.mit.edu	37	1	115220103	115220103	+	Nonsense_Mutation	SNP	G	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr1:115220103G>C	uc001efe.2	-	9	1404	c.1356C>G	c.(1354-1356)taC>taG	p.Y452*	AMPD1_uc001eff.2_Nonsense_Mutation_p.Y448*	NM_000036	NP_000027	P23109	AMPD1_HUMAN	Homo sapiens adenosine monophosphate deaminase 1 (AMPD1), transcript variant 1, mRNA.	419					purine base metabolic process|purine ribonucleoside monophosphate biosynthetic process|purine-containing compound salvage	cytosol	AMP deaminase activity|metal ion binding			NS(1)|breast(1)|endometrium(5)|kidney(1)|large_intestine(10)|lung(17)|ovary(3)|pancreas(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)	45	all_epithelial(7;7.83e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;4.64e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)	Adenosine monophosphate(DB00131)	CAGCATGCTGGTACTTGGCCT	0.582000														61			7		0	0	1	0	0
GCET2	257144	broad.mit.edu	37	3	111842562	111842562	+	Missense_Mutation	SNP	C	A	A			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr3:111842562C>A	uc021xcl.1	-	5	468	c.283G>T	c.(283-285)Gtt>Ttt	p.V95F	C3orf52_uc011bht.1_Intron|C3orf52_uc003dyr.1_Intron|GCET2_uc003dys.2_Missense_Mutation_p.V93F|GCET2_uc021xcm.1_Missense_Mutation_p.V78F	NM_001190259	NP_001177188	Q8N6F7	GCET2_HUMAN	Homo sapiens germinal center expressed transcript 2 (GCET2), transcript variant 3, mRNA.	93						mitochondrion				endometrium(3)|large_intestine(1)|lung(3)|upper_aerodigestive_tract(1)	8						GTACAGAGAACCCGATGATTG	0.483000														129			4		0.000602214	0.000602214	1	1	0
CXCL13	10563	broad.mit.edu	37	4	78528886	78528886	+	Missense_Mutation	SNP	A	G	G			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr4:78528886A>G	uc003hkr.3	+	2	172	c.94A>G	c.(94-96)Agg>Ggg	p.R32G		NM_006419	NP_006410	O43927	CXL13_HUMAN	Homo sapiens chemokine (C-X-C motif) ligand 13 (CXCL13), mRNA.	32					B cell chemotaxis|activation of Rap GTPase activity|cell-cell signaling|chronic inflammatory response|defense response to bacterium|elevation of cytosolic calcium ion concentration|endothelial cell chemotaxis to fibroblast growth factor|germinal center formation|lymphocyte chemotaxis across high endothelial venule|negative regulation of apoptosis|positive regulation of T cell chemotaxis|positive regulation of cell-cell adhesion mediated by integrin|positive regulation of integrin activation|regulation of angiogenesis|regulation of humoral immune response	extracellular space|soluble fraction	CCR10 chemokine receptor binding|CXCR3 chemokine receptor binding|CXCR5 chemokine receptor binding|chemokine activity|fibroblast growth factor 2 binding|heparin binding|protein heterodimerization activity|receptor agonist activity			large_intestine(1)|ovary(1)|skin(1)|urinary_tract(1)	4						CACAAGCTTGAGGTGTAGATG	0.373000														153			4		0	0	1	0	0
GUCY1A3	2982	broad.mit.edu	37	4	156638325	156638325	+	Silent	SNP	C	T	T	rs112384014		TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr4:156638325C>T	uc003iov.3	+	8	2123	c.1587C>T	c.(1585-1587)ggC>ggT	p.G529G	GUCY1A3_uc010iqc.2_Silent_p.G529G|GUCY1A3_uc010iqd.3_Silent_p.G528G|GUCY1A3_uc003iow.3_Silent_p.G529G|GUCY1A3_uc003iox.3_Silent_p.G529G|GUCY1A3_uc010iqe.3_Silent_p.G294G|GUCY1A3_uc003ioy.3_Silent_p.G529G|GUCY1A3_uc003ioz.3_Silent_p.G294G|GUCY1A3_uc003ipa.3_Non-coding_Transcript|GUCY1A3_uc003ipb.3_Silent_p.G529G	NM_000856	NP_001124157	Q02108	GCYA3_HUMAN	Homo sapiens guanylate cyclase 1, soluble, alpha 3 (GUCY1A3), transcript variant 1, mRNA.	529	Guanylate cyclase.			GDAYCVA -> AMPIVWL (in Ref. 1; CAA47145).	blood circulation|intracellular signal transduction|nitric oxide mediated signal transduction|platelet activation	guanylate cyclase complex, soluble	GTP binding|guanylate cyclase activity|heme binding|receptor activity	p.G529G(2)		central_nervous_system(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(25)|liver(2)|lung(19)|ovary(1)|pancreas(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(1)	64	all_hematologic(180;0.24)	Renal(120;0.0854)		COAD - Colon adenocarcinoma(41;0.17)		AGACCATTGGCGATGCCTATT	0.413000														190			10		0	0	1	0	0
FRAS1	80144	broad.mit.edu	37	4	79403634	79403634	+	Silent	SNP	C	T	T			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr4:79403634C>T	uc003hlb.2	+	57	9137	c.8697C>T	c.(8695-8697)gcC>gcT	p.A2899A		NM_025074	NP_079350	Q86XX4	FRAS1_HUMAN	Homo sapiens Fraser syndrome 1 (FRAS1), transcript variant 1, mRNA.	2894					cell communication	integral to membrane|plasma membrane	metal ion binding			breast(2)|central_nervous_system(2)|cervix(2)|endometrium(14)|haematopoietic_and_lymphoid_tissue(2)|kidney(9)|large_intestine(5)|lung(54)|prostate(7)|skin(2)|urinary_tract(4)	103						CACAAGGAGCCGAACTGACCA	0.443000														105			60		0	0	1	0	0
FAM135B	51059	broad.mit.edu	37	8	139165349	139165349	+	Missense_Mutation	SNP	T	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr8:139165349T>C	uc003yuy.3	-	12	1540	c.1369A>G	c.(1369-1371)Agg>Ggg	p.R457G	FAM135B_uc003yux.3_Missense_Mutation_p.R358G|FAM135B_uc003yuz.3_Non-coding_Transcript|FAM135B_uc003yva.3_Missense_Mutation_p.R19G|FAM135B_uc003yvb.3_Missense_Mutation_p.R19G	NM_015912	NP_056996	Q49AJ0	F135B_HUMAN	Homo sapiens family with sequence similarity 135, member B (FAM135B), mRNA.	457										NS(3)|breast(9)|endometrium(21)|kidney(5)|large_intestine(28)|liver(1)|lung(135)|ovary(9)|pancreas(1)|prostate(7)|skin(9)|stomach(1)|upper_aerodigestive_tract(8)|urinary_tract(1)	238	all_epithelial(106;8.29e-14)|Lung NSC(106;6.88e-06)|all_lung(105;1.44e-05)|Ovarian(258;0.00672)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0805)			AGGTCTTCCCTAAAAGATAAA	0.373000										HNSCC(54;0.14)				173			4		0	0	1	0	0
PASK	23178	broad.mit.edu	37	2	242076636	242076636	+	Missense_Mutation	SNP	G	A	A			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr2:242076636G>A	uc002wao.2	-	6	1053	c.920C>T	c.(919-921)aCc>aTc	p.T307I	PASK_uc010zol.2_Missense_Mutation_p.T121I|PASK_uc010zom.2_Missense_Mutation_p.T272I|PASK_uc010fzl.2_Missense_Mutation_p.T307I|PASK_uc010zon.2_Missense_Mutation_p.T88I|PASK_uc021vzf.1_Missense_Mutation_p.T307I|PASK_uc002wap.3_5'Flank|PASK_uc002waq.3_Missense_Mutation_p.T307I	NM_015148	NP_055963	Q96RG2	PASK_HUMAN	Homo sapiens PAS domain containing serine/threonine kinase (PASK), transcript variant 2, mRNA.	307					regulation of transcription, DNA-dependent	Golgi apparatus	ATP binding|identical protein binding|protein serine/threonine kinase activity|signal transducer activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(6)|lung(20)|ovary(4)|prostate(4)|skin(1)|stomach(1)|urinary_tract(2)	53		all_cancers(19;4.46e-39)|all_epithelial(40;1.34e-17)|Breast(86;1.53e-05)|Renal(207;0.00179)|all_lung(227;0.00481)|Lung NSC(271;0.017)|Ovarian(221;0.0228)|Esophageal squamous(248;0.129)|all_hematologic(139;0.158)|Melanoma(123;0.16)|all_neural(83;0.243)|Hepatocellular(293;0.244)		Epithelial(32;1.34e-31)|all cancers(36;1e-28)|OV - Ovarian serous cystadenocarcinoma(60;3.53e-14)|Kidney(56;4.31e-09)|KIRC - Kidney renal clear cell carcinoma(57;4.35e-08)|BRCA - Breast invasive adenocarcinoma(100;5.64e-06)|Lung(119;0.000596)|LUSC - Lung squamous cell carcinoma(224;0.00481)|Colorectal(34;0.014)|COAD - Colon adenocarcinoma(134;0.0968)		AGGGAAGGTGGTACCGTCCCT	0.567000														69			24		0	0	1	0	0
HYDIN	54768	broad.mit.edu	37	GL000192.1	140116	140116	+	RNA	SNP	T	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chrGL000192.1:140116T>C	uc010yih.1	-	17		c.3489A>G						Q4G0P3	HYDIN_HUMAN	Homo sapiens mRNA for KIAA1864 protein, partial cds.											breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(17)|lung(12)|ovary(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)	43		Ovarian(137;0.0654)				GGGGGATGGTTCCCTGCATCA	0.567000														11			3		0	0	1	0	0
LMBRD2	92255	broad.mit.edu	37	5	36136550	36136550	+	Missense_Mutation	SNP	C	T	T			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr5:36136550C>T	uc003jkb.1	-	5	1023	c.608G>A	c.(607-609)gGg>gAg	p.G203E		NM_001007527	NP_001007528	Q68DH5	LMBD2_HUMAN	Homo sapiens LMBR1 domain containing 2 (LMBRD2), mRNA.	203						integral to membrane				breast(2)|endometrium(4)|kidney(3)|large_intestine(7)|lung(12)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	35	all_lung(31;0.000146)		Epithelial(62;0.0396)|Lung(74;0.111)|all cancers(62;0.115)|COAD - Colon adenocarcinoma(61;0.14)|Colorectal(62;0.202)			CAAGCCATACCCCAACAACAA	0.413000														31			53		0	0	1	0	0
SLCO1B3	28234	broad.mit.edu	37	12	21242855	21242855	+	Missense_Mutation	SNP	G	A	A	rs112108376		TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr12:21242855G>A	uc010sil.2	+	15	2127	c.2062G>A	c.(2062-2064)Ggc>Agc	p.G688S	SLCO1B3_uc010sim.2_Missense_Mutation_p.G627S|SLCO1B3_uc010sin.2_Missense_Mutation_p.G580S			Q9NPD5	SO1B3_HUMAN	Homo sapiens solute carrier organic anion transporter family, member 1B3 (SLCO1B3), mRNA.	638					bile acid metabolic process|sodium-independent organic anion transport	basolateral plasma membrane|cytoplasm|integral to plasma membrane	bile acid transmembrane transporter activity|organic anion transmembrane transporter activity			breast(3)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|lung(23)|ovary(2)|prostate(2)|skin(6)|upper_aerodigestive_tract(4)|urinary_tract(2)	63	Esophageal squamous(101;0.149)					AGCCTTCTTCGGCTTGAAGGT	0.303000														152			18		0	0	1	0	0
SERINC3	10955	broad.mit.edu	37	20	43129733	43129733	+	Missense_Mutation	SNP	T	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr20:43129733T>C	uc002xme.3	-	8	1398	c.1264A>G	c.(1264-1266)Acc>Gcc	p.T422A	SERINC3_uc002xmf.1_Missense_Mutation_p.T422A|SERINC3_uc010ggs.1_Missense_Mutation_p.T415A|SERINC3_uc010zwp.1_Missense_Mutation_p.T367A	NM_198941	NP_945179	Q13530	SERC3_HUMAN	Homo sapiens serine incorporator 3 (SERINC3), transcript variant 2, mRNA.	422						integral to membrane|plasma membrane	protein binding			endometrium(4)|large_intestine(2)|lung(8)|skin(3)|urinary_tract(1)	18		Myeloproliferative disorder(115;0.0122)	Colorectal(3;0.000291)|COAD - Colon adenocarcinoma(18;0.00189)			CTGGTCAGGGTCATCATGATG	0.493000														367			7		0	0	1	0	0
KIAA1407	57577	broad.mit.edu	37	3	113775289	113775289	+	Missense_Mutation	SNP	A	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr3:113775289A>C	uc003eax.3	-	0	172	c.25T>G	c.(25-27)Tcc>Gcc	p.S9A	KIAA1407_uc011bin.1_Non-coding_Transcript|KIAA1407_uc011bio.1_Missense_Mutation_p.V47G|KIAA1407_uc011bip.1_Missense_Mutation_p.S9A|QTRTD1_uc003eay.3_5'Flank|QTRTD1_uc003eaz.3_5'Flank|QTRTD1_uc011biq.2_5'Flank|QTRTD1_uc011bir.2_5'Flank	NM_020817	NP_065868	Q8NCU4	K1407_HUMAN	Homo sapiens KIAA1407 (KIAA1407), mRNA.	9										endometrium(9)|large_intestine(7)|lung(19)|ovary(2)|pancreas(1)|prostate(1)|urinary_tract(1)	40						TTTGAGAAGGACCTTCCCTGA	0.602000														15			17		0	0	1	0	0
BRWD3	254065	broad.mit.edu	37	X	79989615	79989615	+	Splice_Site	SNP	A	G	G			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chrX:79989615A>G	uc004edt.3	-	11	1349	c.1086_splice	c.e11+1	p.T362_splice	BRWD3_uc004edp.3_Splice_Site_p.T191_splice|BRWD3_uc004edq.3_Splice_Site|BRWD3_uc010nmj.2_Splice_Site|BRWD3_uc004edr.3_Splice_Site_p.T32_splice|BRWD3_uc004eds.3_Splice_Site|BRWD3_uc004edo.3_Splice_Site|BRWD3_uc004edu.3_Splice_Site_p.T32_splice|BRWD3_uc004edv.3_Splice_Site|BRWD3_uc004edw.3_Splice_Site|BRWD3_uc004edx.3_Splice_Site|BRWD3_uc004edy.3_Splice_Site|BRWD3_uc004edz.3_Splice_Site_p.T32_splice|BRWD3_uc004eea.3_Splice_Site_p.T32_splice|BRWD3_uc004eeb.3_Splice_Site	NM_153252	NP_694984	Q6RI45	BRWD3_HUMAN	Homo sapiens bromodomain and WD repeat domain containing 3 (BRWD3), mRNA.	362										breast(4)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|lung(39)|ovary(4)|prostate(2)|skin(3)	87						ATTTTCTCTTACCGTATGTGA	0.333000														171			4		0	0	1	0	0
ELAVL2	1993	broad.mit.edu	37	9	23762052	23762052	+	Missense_Mutation	SNP	T	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr9:23762052T>C	uc003zpu.3	-	1	456	c.181A>G	c.(181-183)Agc>Ggc	p.S61G	ELAVL2_uc003zps.3_Missense_Mutation_p.S61G|ELAVL2_uc003zpt.3_Missense_Mutation_p.S61G|ELAVL2_uc003zpv.3_Missense_Mutation_p.S61G|ELAVL2_uc003zpw.3_Missense_Mutation_p.S61G	NM_004432	NP_004423	Q12926	ELAV2_HUMAN	Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) (ELAVL2), transcript variant 1, mRNA.	61	RRM 1.				regulation of transcription, DNA-dependent		mRNA 3'-UTR binding|nucleotide binding|protein binding			breast(1)|central_nervous_system(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(8)|lung(20)|ovary(2)|skin(1)|stomach(1)|urinary_tract(1)	39				GBM - Glioblastoma multiforme(1;2.18e-156)|Lung(42;2.15e-28)|LUSC - Lung squamous cell carcinoma(38;1.02e-19)		TCACCAATGCTCCCAAAGAGA	0.393000														158			6		0	0	1	0	0
ZDHHC17	23390	broad.mit.edu	37	12	77216266	77216266	+	Silent	SNP	A	G	G			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr12:77216266A>G	uc001syk.1	+	7	1015	c.852A>G	c.(850-852)aaA>aaG	p.K284K	ZDHHC17_uc001syi.1_Non-coding_Transcript|ZDHHC17_uc001syj.2_Non-coding_Transcript	NM_015336	NP_056151	Q8IUH5	ZDH17_HUMAN	Homo sapiens zinc finger, DHHC-type containing 17 (ZDHHC17), mRNA.	284					lipoprotein transport|positive regulation of I-kappaB kinase/NF-kappaB cascade	Golgi-associated vesicle membrane|integral to membrane	magnesium ion transmembrane transporter activity|protein binding|protein-cysteine S-palmitoleyltransferase activity|signal transducer activity|zinc ion binding			breast(2)|endometrium(2)|large_intestine(3)|liver(2)|lung(14)	23						GGCAAGCAAAAGGATATGACA	0.368000														235			6		0	0	1	0	0
THADA	63892	broad.mit.edu	37	2	43755040	43755040	+	Missense_Mutation	SNP	T	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr2:43755040T>C	uc002rsw.4	-	21	3704	c.3352A>G	c.(3352-3354)Aaa>Gaa	p.K1118E	THADA_uc010far.3_Missense_Mutation_p.K387E|THADA_uc002rsx.4_Missense_Mutation_p.K1118E|THADA_uc002rsy.4_Non-coding_Transcript|THADA_uc010fas.1_Non-coding_Transcript|THADA_uc002rsz.3_Missense_Mutation_p.K827E|THADA_uc010fat.1_Missense_Mutation_p.K265E|THADA_uc002rta.2_Missense_Mutation_p.K828E	NM_001083953	NP_071348	Q6YHU6	THADA_HUMAN	Homo sapiens thyroid adenoma associated (THADA), transcript variant 3, mRNA.	1118							binding			breast(1)|endometrium(9)|kidney(5)|large_intestine(9)|liver(1)|lung(28)|ovary(4)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(5)	66		Acute lymphoblastic leukemia(82;0.00361)|all_hematologic(82;0.00837)				TCAGTGAGTTTCACAAAACCA	0.313000														126			4		0	0	1	0	0
DDX11L9	100288486	broad.mit.edu	37	1	13417	13418	+	Frame_Shift_Ins	INS	-	GAGA	GAGA			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr1:13417_13418insGAGA	uc010nxq.1	+	2	496_497	c.180_181insGAGA	c.(178-183)cccgagfs	p.P60fs	DDX11L9_uc001aaa.3_Non-coding_Transcript|DDX11L9_uc010nxr.1_Non-coding_Transcript					SubName: Full=DEAD/H box polypeptide 11 like 9;																		TCCACCACCCCGAGATCACATT	0.559													---	4	---	---	3	---					
ATPAF1-AS1	374973	broad.mit.edu	37	1	47139255	47139255	+	Splice_Site	DEL	A	-	-			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr1:47139255delA	uc001cqj.3	+	2	859	c.749_splice	c.e2+1		KIAA0494_uc010omh.1_Intron|LOC100130197_uc021ond.1_5'Flank|LOC100130197_uc021one.1_5'Flank	NM_001145474	NP_001138946	Q6PEX7	ATAS1_HUMAN	Homo sapiens ATPAF1 antisense RNA 1 (non-protein coding) (ATPAF1-AS1), mRNA.							integral to membrane				endometrium(3)	3						ACATTAAAAGAAAAAAAAAAA	0.448													---	4	---	---	2	---					
PP14571	100130449	broad.mit.edu	37	2	241390113	241390114	+	Frame_Shift_Ins	INS	-	C	C			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr2:241390113_241390114insC	uc002vyy.1	-	1	739_740	c.455_456insG	c.(454-456)cgafs	p.R152fs	GPC1_uc002vyw.4_Intron					Homo sapiens uncharacterized LOC100130449 (PP14571), non-coding RNA.																		GGGGTGTGGCTCGTGGGCCATG	0.629													---	168	---	---	9	---					
ITGA2	3673	broad.mit.edu	37	5	52376390	52376393	+	Frame_Shift_Del	DEL	TCCC	-	-			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr5:52376390_52376393delTCCC	uc003joy.3	+	24	3121_3124	c.2978_2981delTCCC	c.(2977-2982)atccctfs	p.I993fs	ITGA2_uc011cqa.2_Non-coding_Transcript|ITGA2_uc011cqb.2_Non-coding_Transcript|ITGA2_uc011cqc.2_Frame_Shift_Del_p.I917fs|ITGA2_uc011cqd.2_Non-coding_Transcript|ITGA2_uc011cqe.2_Non-coding_Transcript	NM_002203	NP_002194	P17301	ITA2_HUMAN	Homo sapiens integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), mRNA.	993					axon guidance|blood coagulation|cell-matrix adhesion|integrin-mediated signaling pathway|interspecies interaction between organisms|organ morphogenesis	integrin complex	collagen binding|identical protein binding|receptor activity			breast(3)|central_nervous_system(2)|endometrium(5)|kidney(3)|large_intestine(8)|liver(1)|lung(18)|pancreas(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	47		Lung NSC(810;3.11e-05)|Breast(144;0.014)|Prostate(461;0.0181)				ATCATCCACATCCCTCAGTATACC	0.387													---	32	---	---	25	---					
SIRT1	23411	broad.mit.edu	37	10	69648852	69648852	+	Frame_Shift_Del	DEL	A	-	-			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr10:69648852delA	uc001jnd.3	+	2	813	c.760delA	c.(760-762)aaafs	p.K254fs	SIRT1_uc010qis.2_Intron|SIRT1_uc009xpp.3_Frame_Shift_Del_p.K62fs|SIRT1_uc001jne.3_5'Flank	NM_012238	NP_001135970	Q96EB6	SIRT1_HUMAN	Homo sapiens sirtuin 1 (SIRT1), transcript variant 1, mRNA.	254	Deacetylase sirtuin-type.|Interaction with HIST1H1E.				DNA repair|DNA replication|apoptosis|cell aging|cellular response to hydrogen peroxide|cellular response to starvation|chromatin silencing at rDNA|establishment of chromatin silencing|histone H3 deacetylation|interspecies interaction between organisms|maintenance of chromatin silencing|muscle organ development|negative regulation of DNA damage response, signal transduction by p53 class mediator|negative regulation of androgen receptor signaling pathway|negative regulation of cell growth|negative regulation of fat cell differentiation|negative regulation of helicase activity|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|peptidyl-lysine acetylation|peptidyl-lysine deacetylation|positive regulation of DNA repair|positive regulation of anti-apoptosis|positive regulation of chromatin silencing|rRNA processing|regulation of apoptosis|regulation of cell proliferation|regulation of endodeoxyribonuclease activity|regulation of protein import into nucleus, translocation|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|transcription, DNA-dependent|triglyceride mobilization|white fat cell differentiation	PML body|chromatin silencing complex|cytoplasm|nuclear euchromatin|nuclear heterochromatin|nuclear inner membrane|nucleolus|rDNA heterochromatin	HLH domain binding|NAD+ binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|bHLH transcription factor binding|histone binding|identical protein binding|mitogen-activated protein kinase binding|p53 binding|protein C-terminus binding|transcription corepressor activity|zinc ion binding			central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(6)|lung(3)|skin(1)	14						GCAAGAGTGCAAAAAAATTAT	0.333													---	4	---	---	2	---					
LOC648809	648809	broad.mit.edu	37	15	84790370	84790371	+	Frame_Shift_Ins	INS	-	A	A			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr15:84790370_84790371insA	uc021stg.1	+	8	976_977	c.492_493insA	c.(490-495)aagaaafs	p.K164fs						Homo sapiens elongation factor Tu GTP-binding domain-containing protein 1 pseudogene (LOC648809), non-coding RNA.																		GAAGAGGAAAGAAAATTTTTGT	0.401													---	126	---	---	10	---					
CEP76	79959	broad.mit.edu	37	18	12699829	12699829	+	Splice_Site	DEL	T	-	-			TCGA-KO-8410-01A-11D-2310-10	TCGA-KO-8410-11A-01D-2311-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	798bd17b-69b7-40d7-92ff-7c2389edcccf	01229abb-7ade-4ab4-be30-3406270b8e6d	g.chr18:12699829delT	uc002kri.3	-	3	451	c.295_splice	c.e3+1	p.T99_splice	PSMG2_uc002krg.3_Intron|CEP76_uc002krh.3_Splice_Site|CEP76_uc010wzz.2_Splice_Site_p.S99_splice|CEP76_uc010xaa.1_Splice_Site|CEP76_uc010xab.1_Splice_Site_p.S99_splice	NM_024899	NP_079175	Q8TAP6	CEP76_HUMAN	Homo sapiens centrosomal protein 76kDa (CEP76), mRNA.	99					G2/M transition of mitotic cell cycle|regulation of centriole replication	centriole|cytosol	protein binding	p.T99fs*90(1)		endometrium(1)|kidney(3)|large_intestine(5)|lung(7)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	21						ATATACATACTTTTTTTTAAT	0.318													---	230	---	---	7	---					
