Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	transcript_name	strand	transcript_status	amino_acid_change	ucsc_cons	normal_depth	normal_vaf	tumor_depth	tumor_vaf	rna_depth	rna_vaf	polyphen	sift	condel	domain
TP73-AS1	57212	genome.wustl.edu	37	1	3662321	3662321	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_207306.2	-1	predicted	p.L149	0.010	11	0%	22	36.4%	-	-	-	-	-	NULL
SPSB1	80176	genome.wustl.edu	37	1	9416307	9416307	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_025106.3	+1	validated	p.T119	0.019	24	0%	23	43.5%	-	-	-	-	-	HMMPfam_SPRY,HMMSmart_SPRY
PIK3CD	5293	genome.wustl.edu	37	1	9783218	9783218	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005026.3	+1	validated	p.R821H	0.967	41	0%	71	47.9%	-	-	benign(0.026)	tolerated(0.06)	neutral(0.324)	HMMPfam_PI3_PI4_kinase,HMMSmart_PI3Kc,superfamily_Kinase_like
PDPN	10630	genome.wustl.edu	37	1	13936948	13936948	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006474.4	+1	reviewed	p.V166I	0.011	143	0%	181	52.5%	-	-	benign(0.094)	tolerated(0.69)	neutral(0.009)	HMMPfam_Podoplanin
PINK1	65018	genome.wustl.edu	37	1	20975093	20975093	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032409.2	+1	reviewed	p.R407W	1.000	32	0%	20	55%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase
USP48	84196	genome.wustl.edu	37	1	22048218	22048218	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032236.5	-1	reviewed	p.R563H	1.000	59	0%	70	54.3%	-	-	probably_damaging(0.997)	deleterious(0.04)	deleterious(0.815)	NULL
ARID1A	8289	genome.wustl.edu	37	1	27088739	27088739	+	Frame_Shift_Del	DEL	C	C	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006015.4	+1	reviewed	p.T783fs	1.000	-	-	-	-	-	-	-	-	-	NULL
PHACTR4	65979	genome.wustl.edu	37	1	28802786	28802786	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_023923.3	+1	reviewed	p.E540G	1.000	128	0%	122	43.4%	-	-	possibly_damaging(0.588)	tolerated(0.06)	deleterious(0.526)	NULL
S100PBP	64766	genome.wustl.edu	37	1	33321534	33321534	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022753.2	+1	validated	p.A374	0.996	76	0%	96	36.5%	-	-	-	-	-	NULL
SLFNL1	200172	genome.wustl.edu	37	1	41483462	41483462	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_144990.3	-1	validated	p.V268M	0.997	74	0%	67	47.8%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMPfam_AAA_4
JAK1	3716	genome.wustl.edu	37	1	65316544	65316544	+	Frame_Shift_Del	DEL	G	G	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002227.2	-1	reviewed	p.V567fs	0.004	-	-	-	-	-	-	-	-	-	superfamily_SSF55550
GIPC2	54810	genome.wustl.edu	37	1	78560689	78560689	+	Missense_Mutation	SNP	T	T	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017655.4	+1	validated	p.D160E	1.000	238	0%	273	46.2%	-	-	probably_damaging(0.998)	deleterious(0.01)	deleterious(0.880)	HMMPfam_PDZ,HMMSmart_PDZ,superfamily_PDZ
DNTTIP2	30836	genome.wustl.edu	37	1	94342647	94342647	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014597.3	-1	provisional	p.E282K	0.000	137	0%	139	12.9%	-	-	benign(0)	tolerated(0.85)	neutral(0.001)	NULL
SYT6	148281	genome.wustl.edu	37	1	114640423	114640423	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_205848.2	-1	validated	p.E396K	1.000	137	0%	151	43.7%	-	-	probably_damaging(0.999)	deleterious(0.01)	deleterious(0.896)	HMMSmart_C2,superfamily_C2_CaLB
HSD3B1	3283	genome.wustl.edu	37	1	120050194	120050194	+	Missense_Mutation	SNP	T	T	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000862.2	+1	validated	p.I32N	0.985	369	0%	368	45.1%	-	-	probably_damaging(0.965)	deleterious(0)	deleterious(0.851)	HMMPfam_3Beta_HSD,superfamily_NAD(P)-bd
NBPF7	343505	genome.wustl.edu	37	1	120385056	120385056	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001047980.1	-1	predicted	p.R113M	0.005	191	0%	260	47.3%	-	-	-	-	-	NULL
PIAS3	10401	genome.wustl.edu	37	1	145585509	145585509	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006099.3	+1	reviewed	p.R592S	1.000	125	0%	123	48%	-	-	benign(0.006)	tolerated(0.65)	neutral(0.003)	NULL
PRKAB2	5565	genome.wustl.edu	37	1	146639477	146639477	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005399.3	-1	reviewed	p.Q64	0.996	224	0%	289	47.8%	-	-	-	-	-	NULL
SV2A	9900	genome.wustl.edu	37	1	149885237	149885237	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014849.3	-1	validated	p.E52D	0.178	251	0%	303	42.6%	-	-	benign(0.001)	tolerated(0.12)	neutral(0.261)	NULL
C1orf51	148523	genome.wustl.edu	37	1	150259121	150259121	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_144697.2	+1	predicted	p.H305N	0.563	530	0.2%	653	30.8%	-	-	benign(0.301)	deleterious(0)	deleterious(0.537)	NULL
DCST1	149095	genome.wustl.edu	37	1	155012971	155012971	+	Silent	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152494.2	+1	validated	p.A134	1.000	17	0.000	7	0.714	-	-	-	-	-	NULL
ADAM15	8751	genome.wustl.edu	37	1	155034944	155034944	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_207197.1	+1	reviewed	p.P853Q	0.819	9	0.000	12	0.333	-	-	unknown(0)	deleterious(0.03)	-	NULL
SLAMF8	56833	genome.wustl.edu	37	1	159802795	159802795	+	Missense_Mutation	SNP	G	G	A	rs186733189	by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020125.2	+1	reviewed	p.R166Q	0.606	179	0%	217	42.9%	-	-	benign(0.076)	tolerated(0.42)	neutral(0.019)	superfamily_Immunoglobulin
IGSF8	93185	genome.wustl.edu	37	1	160062723	160062723	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_052868.2	-1	provisional	p.R435W	0.909	161	0%	111	45.9%	-	-	probably_damaging(1)	deleterious(0.02)	deleterious(0.883)	HMMSmart_SM00409
RGS4	5999	genome.wustl.edu	37	1	163039248	163039249	+	Frame_Shift_Ins	INS	-	-	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001102445.2	+1	reviewed	p.A90fs	0.000:0.001	-	-	-	-	-	-	-	-	-	NULL
NUF2	83540	genome.wustl.edu	37	1	163317706	163317706	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_031423.3	+1	reviewed	p.Q368K	0.885	149	0.7%	184	10.9%	-	-	possibly_damaging(0.769)	deleterious(0.03)	deleterious(0.650)	NULL
BLZF1	8548	genome.wustl.edu	37	1	169346175	169346175	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003666.2	+1	validated	p.Q142H	1.000	242	0%	222	37.4%	-	-	probably_damaging(0.997)	deleterious(0)	deleterious(0.911)	NULL
PRRC2C	23215	genome.wustl.edu	37	1	171510116	171510116	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015172.3	+1	validated	p.T1169A	1.000	127	0%	121	38.8%	-	-	unknown(0)	-	-	NULL
TNN	63923	genome.wustl.edu	37	1	175113677	175113677	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022093.1	+1	validated	p.K1250	0.998	135	0%	149	18.1%	-	-	-	-	-	HMMPfam_Fibrinogen_C,HMMSmart_SM00186,superfamily_Fibrinogen C-terminal domain-like
CACNA1E	777	genome.wustl.edu	37	1	181754899	181754899	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000721.2	+1	reviewed	p.E1910D	1.000	443	0%	496	10.1%	-	-	benign(0.019)	tolerated(0.24)	neutral(0.038)	NULL
APOBEC4	403314	genome.wustl.edu	37	1	183616942	183616942	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_203454.2	-1	reviewed	p.M325I	0.002	308	0%	270	45.9%	-	-	benign(0)	tolerated(0.13)	neutral(0.253)	NULL
HMCN1	83872	genome.wustl.edu	37	1	185834941	185834941	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_031935.2	+1	reviewed	p.I189	1.000	155	0%	185	44.3%	-	-	-	-	-	superfamily_vWA-like
IGFN1	91156	genome.wustl.edu	37	1	201190806	201190806	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000451870	+1	known	p.A921V	0.995	75	0%	80	22.5%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III
LAD1	3898	genome.wustl.edu	37	1	201352317	201352317	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005558.3	-1	reviewed	p.R424Q	0.005	180	0%	235	43.4%	-	-	benign(0.116)	tolerated(0.3)	neutral(0.037)	NULL
PPFIA4	8497	genome.wustl.edu	37	1	203040888	203040888	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015053.1	+1	validated	p.D625	0.819	35	0%	35	45.7%	-	-	-	-	-	NULL
TMCC2	9911	genome.wustl.edu	37	1	205241234	205241234	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014858.3	+1	validated	p.H704	0.996	34	0%	44	31.8%	-	-	-	-	-	NULL
NUCKS1	64710	genome.wustl.edu	37	1	205696903	205696903	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022731.3	-1	validated	p.P33L	0.999	101	0%	99	39.4%	-	-	probably_damaging(0.997)	deleterious(0.01)	deleterious(0.872)	NULL
PLXNA2	5362	genome.wustl.edu	37	1	208272285	208272285	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_025179.3	-1	reviewed	p.A546V	1.000	18	0%	16	50%	-	-	probably_damaging(0.991)	tolerated(0.06)	deleterious(0.766)	HMMPfam_PSI,HMMSmart_SM00423,superfamily_Plexin repeat
KCNH1	3756	genome.wustl.edu	37	1	210971025	210971025	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_172362.2	-1	reviewed	p.P580	0.001	79	0%	76	46.1%	-	-	-	-	-	superfamily_cAMP-binding domain-like
USH2A	7399	genome.wustl.edu	37	1	215847527	215847527	+	Nonsense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_206933.2	-1	reviewed	p.E4576*	0.148	482	0%	482	41.9%	-	-	-	-	-	HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III
DUSP10	11221	genome.wustl.edu	37	1	221875919	221875919	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007207.3	-1	reviewed	p.R428	1.000	226	0%	178	33.7%	-	-	-	-	-	HMMPfam_DSPc,HMMSmart_SM00195,superfamily_(Phosphotyrosine protein) phosphatases II
ABCB10	23456	genome.wustl.edu	37	1	229665986	229665986	+	Silent	SNP	T	T	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_012089.2	-1	reviewed	p.T535	0.141	207	0%	248	12.9%	-	-	-	-	-	HMMPfam_ABC_tran,HMMSmart_AAA,superfamily_SSF52540
KIAA1804	84451	genome.wustl.edu	37	1	233489618	233489618	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032435.2	+1	validated	p.A351V	0.998	205	0%	193	15%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase
RYR2	6262	genome.wustl.edu	37	1	237949334	237949334	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001035.2	+1	reviewed	p.A4442	0.561	84	0%	93	11.8%	-	-	-	-	-	HMMPfam_RR_TM4-6
ATP6V1C2	245973	genome.wustl.edu	37	2	10917818	10917819	+	Frame_Shift_Ins	INS	-	-	AG	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001039362.1	+1	reviewed	p.E315fs	1.000:1.000	-	-	-	-	-	-	-	-	-	HMMPfam_V-ATPase_C
APOB	338	genome.wustl.edu	37	2	21239325	21239325	+	Silent	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000384.2	-1	reviewed	p.L1106	0.043	144	0%	136	35.3%	-	-	-	-	-	NULL
OTOF	9381	genome.wustl.edu	37	2	26683866	26683866	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_194248.2	-1	reviewed	p.R1856W	0.992	33	3%	42	45.2%	-	-	probably_damaging(0.997)	deleterious(0)	deleterious(0.911)	HMMSmart_SM00239,superfamily_C2 domain (Calcium/lipid-binding domain CaLB)
CAD	790	genome.wustl.edu	37	2	27448706	27448706	+	Missense_Mutation	SNP	C	C	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004341.3	+1	reviewed	p.T585S	1.000	138	0%	107	54.2%	-	-	benign(0.018)	tolerated(1)	neutral(0.001)	HMMPfam_CPSase_L_D2,superfamily_SSF56059
SLC30A3	7781	genome.wustl.edu	37	2	27480152	27480152	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003459.4	-1	validated	p.P216Q	0.999	15	0%	23	52.2%	-	-	benign(0.047)	tolerated(0.41)	neutral(0.018)	HMMPfam_Cation_efflux
C2orf16	84226	genome.wustl.edu	37	2	27803722	27803722	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032266.3	+1	validated	p.L1428S	0.000	125	0%	163	45.4%	-	-	possibly_damaging(0.68)	deleterious(0)	deleterious(0.687)	NULL
SLC8A1	6546	genome.wustl.edu	37	2	40342722	40342722	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_021097.2	-1	validated	p.A865T	1.000	107	0%	122	19.7%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMPfam_Na_Ca_ex
PLEKHH2	130271	genome.wustl.edu	37	2	43939469	43939469	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_172069.3	+1	validated	p.P803S	1.000	107	0%	115	46.1%	-	-	probably_damaging(0.991)	tolerated(0.08)	deleterious(0.744)	superfamily_PH domain-like
MTIF2	4528	genome.wustl.edu	37	2	55481207	55481207	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001005369.1	-1	reviewed	p.G212C	1.000	123	0%	129	39.5%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_GTP_EFTU,superfamily_SSF52540
FAM161A	84140	genome.wustl.edu	37	2	62067223	62067223	+	Missense_Mutation	SNP	G	G	A	rs183615774	by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032180.2	-1	validated	p.R306W	0.991	311	0%	370	45.7%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_UPF0564
ASPRV1	151516	genome.wustl.edu	37	2	70188817	70188817	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152792.2	-1	validated	p.G2W	0.969	139	0%	111	41.4%	-	-	probably_damaging(0.994)	deleterious(0)	deleterious(0.897)	NULL
SLC4A5	57835	genome.wustl.edu	37	2	74460641	74460641	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_021196.3	-1	reviewed	p.P828L	0.997	68	0%	50	12%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_HCO3_cotransp
C2orf15	150590	genome.wustl.edu	37	2	99767295	99767295	+	Nonstop_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_144706.2	+1	predicted	p.*126R	0.999	99	0%	118	17.8%	-	-	-	-	-	NULL
UGGT1	56886	genome.wustl.edu	37	2	128918111	128918111	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020120.3	+1	validated	p.C880	1.000	59	0%	54	50%	-	-	-	-	-	NULL
NCKAP5	344148	genome.wustl.edu	37	2	133554303	133554303	+	Splice_Site	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_207363.2	-1	validated	e10-1	1.000	53	0%	35	40%	-	-	-	-	-	-
GRB14	2888	genome.wustl.edu	37	2	165358837	165358837	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004490.2	-1	reviewed	p.M344I	1.000	37	0%	63	39.7%	-	-	benign(0.253)	tolerated(0.3)	neutral(0.054)	HMMSmart_PH,superfamily_SSF50729
NOSTRIN	115677	genome.wustl.edu	37	2	169690740	169690742	+	Splice_Site	DEL	AAG	AAG	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	AAG	AAG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000458381	+1	known	e7-1	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	-
RAPGEF4	11069	genome.wustl.edu	37	2	173679122	173679122	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007023.3	+1	validated	p.I138T	0.999	190	0%	186	51.1%	-	-	benign(0.046)	deleterious(0)	neutral(0.447)	HMMPfam_cNMP_binding,HMMSmart_SM00100,superfamily_cAMP-binding domain-like
RAPGEF4	11069	genome.wustl.edu	37	2	173832079	173832081	+	In_Frame_Del	DEL	AGA	AGA	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	AGA	AGA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007023.3	+1	validated	p.K306in_frame_del	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	"superfamily_""Winged helix"" DNA-binding domain"
DFNB59	494513	genome.wustl.edu	37	2	179320752	179320752	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000442710	+1	known	p.P89S	0.990	42	0%	53	43.4%	-	-	-	-	-	NULL
TTN	7273	genome.wustl.edu	37	2	179441333	179441333	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000356127	-1	known	p.R20643H	1.000	163	0%	191	31.9%	-	-	probably_damaging(1)	-	-	HMMPfam_fn3,HMMSmart_SM00060
TFPI	7035	genome.wustl.edu	37	2	188349619	188349619	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006287.4	-1	reviewed	p.R152C	0.016	132	0%	170	25.3%	-	-	probably_damaging(0.997)	deleterious(0.01)	deleterious(0.872)	HMMPfam_Kunitz_BPTI,HMMSmart_SM00131,superfamily_BPTI-like
MFSD6	54842	genome.wustl.edu	37	2	191300862	191300862	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017694.3	+1	validated	p.P36H	0.996	183	0%	191	46.6%	-	-	probably_damaging(0.995)	deleterious(0.01)	deleterious(0.863)	superfamily_MFS_gen_substrate_transporter
SATB2	23314	genome.wustl.edu	37	2	200173513	200173513	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015265.3	-1	reviewed	p.H570	0.108	138	0%	126	12.7%	-	-	-	-	-	NULL
CRYGA	1418	genome.wustl.edu	37	2	209025703	209025703	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014617.3	-1	validated	p.R117H	0.078	81	0%	110	53.6%	-	-	benign(0.001)	tolerated(0.71)	neutral(0.002)	HMMPfam_Crystall,HMMSmart_SM00247,superfamily_gamma-Crystallin-like
ZFAND2B	130617	genome.wustl.edu	37	2	220072128	220072128	+	Silent	SNP	A	A	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_138802.1	+1	provisional	p.G45	0.937	71	0%	73	38.4%	-	-	-	-	-	HMMPfam_zf-AN1,HMMSmart_SM00154
CCDC140	151278	genome.wustl.edu	37	2	223168833	223168833	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_153038.1	+1	validated	p.P71L	0.000	49	0%	66	43.9%	-	-	unknown(0)	-	-	NULL
GIGYF2	26058	genome.wustl.edu	37	2	233712227	233712229	+	In_Frame_Del	DEL	ACA	ACA	-	rs58340018		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	ACA	ACA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001103147.1	+1	reviewed	p.Q1235in_frame_del	0.057:0.094:0.124	-	-	-	-	-	-	-	-	-	NULL
NGEF	25791	genome.wustl.edu	37	2	233785159	233785159	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_019850.2	-1	validated	p.E221	0.996	35	0%	36	13.9%	-	-	-	-	-	NULL
TRPM8	79054	genome.wustl.edu	37	2	234846018	234846018	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024080.4	+1	validated	p.G71	0.997	156	0%	170	49.4%	-	-	-	-	-	NULL
RPUSD3	285367	genome.wustl.edu	37	3	9883682	9883682	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173659.3	-1	validated	p.V131A	0.973	234	0%	261	40.6%	-	-	probably_damaging(0.998)	deleterious(0)	deleterious(0.919)	HMMPfam_PseudoU_synth_2,superfamily_Pseudouridine synthase
IL17RE	132014	genome.wustl.edu	37	3	9950947	9950947	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_153480.1	+1	reviewed	p.F261S	1.000	40	0%	33	36.4%	-	-	probably_damaging(0.999)	deleterious(0)	deleterious(0.935)	NULL
TOP2B	7155	genome.wustl.edu	37	3	25651066	25651068	+	In_Frame_Del	DEL	CTT	CTT	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	CTT	CTT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001068.2	-1	reviewed	p.K1303in_frame_del	0.999:1.000:1.000	-	-	-	-	-	-	-	-	-	NULL
OXSM	54995	genome.wustl.edu	37	3	25833400	25833400	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017897.2	+1	reviewed	p.R297W	0.996	152	0%	169	14.2%	-	-	probably_damaging(0.998)	deleterious(0)	deleterious(0.919)	superfamily_Thiolase-like
RPSA	3921	genome.wustl.edu	37	3	39453847	39453847	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001012321.1	+1	reviewed	p.T292	0.530	71	0%	70	35.7%	-	-	-	-	-	NULL
CTNNB1	1499	genome.wustl.edu	37	3	41266112	41266112	+	Missense_Mutation	SNP	T	T	G	rs121913228	byCluster	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001098209.1	+1	reviewed	p.S37A	1.000	61	0%	91	51.6%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	NULL
COL7A1	1294	genome.wustl.edu	37	3	48602896	48602896	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000094.3	-1	reviewed	p.G2825D	0.001	34	0%	34	41.2%	-	-	unknown(0)	deleterious(0)	-	NULL
KLHDC8B	200942	genome.wustl.edu	37	3	49213142	49213142	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173546.1	+1	provisional	p.L325	0.988	55	0%	60	51.7%	-	-	-	-	-	HMMSmart_Kelch,superfamily_Gal_oxid_central
MST1R	4486	genome.wustl.edu	37	3	49928692	49928692	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000434765	-1	known	p.A172V	0.000	37	0%	34	44.1%	-	-	-	-	-	HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like)
COL8A1	1295	genome.wustl.edu	37	3	99514882	99514882	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001850.3	+1	reviewed	p.R713W	0.702	49	0%	48	50%	-	-	possibly_damaging(0.836)	deleterious(0.02)	deleterious(0.703)	HMMPfam_C1q,HMMSmart_SM00110,superfamily_TNF-like
PIK3CB	5291	genome.wustl.edu	37	3	138374301	138374301	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006219.1	-1	provisional	p.A1048V	1.000	221	0%	258	41.1%	-	-	probably_damaging(0.999)	deleterious(0)	deleterious(0.935)	HMMSmart_PI3Kc,superfamily_Kinase_like
PLS1	5357	genome.wustl.edu	37	3	142422826	142422826	+	Silent	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001145319.1	+1	reviewed	p.V496	0.221	80	0%	78	15.4%	-	-	-	-	-	PatternScan_ACTININ_2,HMMPfam_CH,HMMSmart_CH,superfamily_Calponin-homology
TRPC1	7220	genome.wustl.edu	37	3	142499741	142499741	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003304.4	+1	validated	p.R243Q	1.000	105	0%	116	39.7%	-	-	probably_damaging(0.999)	deleterious(0)	deleterious(0.935)	NULL
AADAC	13	genome.wustl.edu	37	3	151545954	151545954	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001086.2	+1	reviewed	p.N398	1.000	91	0%	113	44.2%	-	-	-	-	-	superfamily_alpha/beta-Hydrolases
PIK3CA	5290	genome.wustl.edu	37	3	178952085	178952085	+	Missense_Mutation	SNP	A	A	T	rs121913279	byCluster	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006218.2	+1	reviewed	p.H1047L	1.000	137	0%	180	45.6%	-	-	possibly_damaging(0.815)	tolerated(1)	neutral(0.307)	HMMSmart_PI3Kc,superfamily_Kinase_like
DVL3	1857	genome.wustl.edu	37	3	183888444	183888444	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004423.3	+1	reviewed	p.G684	1.000	14	0%	17	47.1%	-	-	-	-	-	NULL
SENP2	59343	genome.wustl.edu	37	3	185304233	185304233	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_021627.2	+1	validated	p.T11N	1.000	34	0%	66	13.6%	-	-	benign(0.348)	deleterious(0)	deleterious(0.554)	NULL
DGKG	1608	genome.wustl.edu	37	3	185997705	185997705	+	Nonsense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001346.2	-1	reviewed	p.Q243*	0.954	293	0%	313	39.6%	-	-	-	-	-	HMMSmart_SM00054,PatternScan_EF_HAND_1,superfamily_EF-hand,superfamily_Cysteine-rich domain
WDR53	348793	genome.wustl.edu	37	3	196288294	196288294	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_182627.1	-1	provisional	p.A18V	0.908	85	0%	80	46.3%	-	-	benign(0.001)	tolerated(1)	-	HMMSmart_SM00320,superfamily_WD40 repeat-like
HTT	3064	genome.wustl.edu	37	4	3156111	3156111	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002111.6	+1	reviewed	p.P1197L	0.978	61	0%	28	53.6%	-	-	probably_damaging(1)	tolerated(0.26)	deleterious(0.534)	NULL
MSANTD1	345222	genome.wustl.edu	37	4	3265632	3265632	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000341755	+1	known	p.T250	0.002	253	0%	249	45%	-	-	-	-	-	NULL
KIAA0232	9778	genome.wustl.edu	37	4	6862960	6862960	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001100590.1	+1	validated	p.R284H	0.980	143	0.7%	134	41%	-	-	probably_damaging(0.984)	deleterious(0)	deleterious(0.875)	NULL
PPARGC1A	10891	genome.wustl.edu	37	4	23825936	23825936	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_013261.3	-1	reviewed	p.R282C	1.000	266	0.4%	312	47.4%	-	-	probably_damaging(0.966)	deleterious(0)	deleterious(0.853)	NULL
USP46	64854	genome.wustl.edu	37	4	53494169	53494171	+	In_Frame_Del	DEL	CTT	CTT	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	CTT	CTT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022832.3	-1	validated	p.K93in_frame_del	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	HMMPfam_UCH,superfamily_Cysteine proteinases
SHROOM3	57619	genome.wustl.edu	37	4	77661775	77661775	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020859.3	+1	validated	p.T817A	0.000	65	0%	74	44.6%	-	-	benign(0.009)	tolerated(0.4)	neutral(0.017)	NULL
PTPN13	5783	genome.wustl.edu	37	4	87684281	87684281	+	Nonsense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_080685.2	+1	reviewed	p.G1319*	1.000	339	0%	426	38.7%	-	-	-	-	-	NULL
DMP1	1758	genome.wustl.edu	37	4	88583159	88583159	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004407.3	+1	reviewed	p.G77C	0.010	126	0%	139	48.9%	-	-	probably_damaging(0.999)	deleterious(0.01)	deleterious(0.896)	HMMPfam_DMP1
HERC3	8916	genome.wustl.edu	37	4	89574213	89574213	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014606.1	+1	provisional	p.A219	0.978	70	0%	71	36.6%	-	-	-	-	-	HMMPfam_RCC1,superfamily_RCC1/BLIP-II
DDIT4L	115265	genome.wustl.edu	37	4	101109162	101109162	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_145244.2	-1	provisional	p.T85I	1.000	118	0%	131	46.6%	-	-	probably_damaging(0.989)	tolerated(0.46)	neutral(0.452)	HMMPfam_RTP801_C
HSPA4L	22824	genome.wustl.edu	37	4	128732695	128732695	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014278.2	+1	provisional	p.S494	1.000	103	0%	116	46.6%	-	-	-	-	-	HMMPfam_HSP70,superfamily_SSF100920
ARHGAP10	79658	genome.wustl.edu	37	4	148800422	148800422	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024605.3	+1	validated	p.C291Y	1.000	211	0%	239	41%	-	-	probably_damaging(0.996)	deleterious(0)	deleterious(0.906)	HMMPfam_PH,HMMSmart_PH,superfamily_SSF50729
TRIM2	23321	genome.wustl.edu	37	4	154237081	154237081	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015271.3	+1	validated	p.S571N	1.000	121	0%	137	38%	-	-	benign(0)	tolerated(0.96)	-	HMMPfam_NHL,superfamily_NHL repeat
DDX60L	91351	genome.wustl.edu	37	4	169377257	169377257	+	Nonsense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001012967.1	-1	validated	p.S257*	0.055	72	0%	61	21.3%	-	-	-	-	-	NULL
MFAP3L	9848	genome.wustl.edu	37	4	170913366	170913366	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_021647.6	-1	validated	p.Y131	0.976	147	0%	151	11.3%	-	-	-	-	-	HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_I-set,superfamily_Immunoglobulin
MTNR1A	4543	genome.wustl.edu	37	4	187455686	187455686	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005958.3	-1	reviewed	p.A70	0.015	43	0%	79	40.5%	-	-	-	-	-	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like
TRIP13	9319	genome.wustl.edu	37	5	908513	908513	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004237.3	+1	reviewed	p.T268N	0.950	83	0%	99	37.4%	-	-	benign(0.001)	tolerated(0.69)	neutral(0.002)	HMMSmart_SM00382,HMMPfam_AAA,superfamily_P-loop containing nucleoside triphosphate hydrolases
DNAH5	1767	genome.wustl.edu	37	5	13727634	13727634	+	Silent	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001369.2	-1	reviewed	p.P4005	0.153	127	0%	129	42.6%	-	-	-	-	-	HMMPfam_Dynein_heavy
FBXL7	23194	genome.wustl.edu	37	5	15936981	15936981	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_012304.3	+1	reviewed	p.G388C	1.000	58	0%	59	57.6%	-	-	probably_damaging(0.986)	deleterious(0.04)	deleterious(0.783)	HMMSmart_SM00367,superfamily_RNI-like
LOC729862	729862	genome.wustl.edu	37	5	28927076	28927076	+	RNA	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	XR_040872.2	+1	model	NULL	0.819	33	0%	37	62.2%	-	-	-	-	-	-
NIPBL	25836	genome.wustl.edu	37	5	37007560	37007561	+	Frame_Shift_Del	DEL	AC	AC	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	AC	AC					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_133433.3	+1	reviewed	p.T1409fs	1.000:0.996	-	-	-	-	-	-	-	-	-	superfamily_ARM repeat
HEATR7B2	133558	genome.wustl.edu	37	5	41005726	41005726	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173489.4	-1	validated	p.H1257	0.000	39	0%	34	44.1%	-	-	-	-	-	superfamily_ARM repeat
KIF2A	3796	genome.wustl.edu	37	5	61653537	61653537	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001098511.1	+1	validated	p.C225Y	1.000	28	0%	38	47.4%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMSmart_KISc,superfamily_SSF52540
PAPD4	167153	genome.wustl.edu	37	5	78915846	78915846	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001114393.1	+1	validated	p.L56P	0.915	61	0%	76	36.8%	-	-	possibly_damaging(0.931)	deleterious(0.03)	deleterious(0.742)	NULL
CMYA5	202333	genome.wustl.edu	37	5	79030553	79030553	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_153610.3	+1	validated	p.E1989K	0.005	200	0%	221	42.1%	-	-	benign(0.139)	deleterious(0.02)	neutral(0.395)	NULL
ZFYVE16	9765	genome.wustl.edu	37	5	79733528	79733528	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001105251.1	+1	validated	p.A342T	0.081	174	0%	135	18.5%	-	-	benign(0.004)	tolerated(0.27)	neutral(0.034)	NULL
APC	324	genome.wustl.edu	37	5	112174009	112174009	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000038.4	+1	reviewed	p.S906	0.913	153	0%	197	48.2%	-	-	-	-	-	NULL
TSSK1B	83942	genome.wustl.edu	37	5	112770059	112770059	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032028.3	-1	validated	p.R160C	1.000	137	0%	149	43%	-	-	probably_damaging(0.996)	tolerated(0.17)	deleterious(0.520)	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase
YTHDC2	64848	genome.wustl.edu	37	5	112876808	112876808	+	Nonsense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022828.3	+1	validated	p.Q452*	1.000	311	0%	355	47.6%	-	-	-	-	-	NULL
FBN2	2201	genome.wustl.edu	37	5	127595357	127595357	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001999.3	-1	reviewed	p.S2843	0.007	172	0%	180	48.9%	-	-	-	-	-	NULL
KDM3B	51780	genome.wustl.edu	37	5	137727401	137727401	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_016604.3	+1	validated	p.I694V	1.000	110	0%	116	39.7%	-	-	benign(0.034)	tolerated(0.06)	neutral(0.325)	NULL
PCDHA8	56140	genome.wustl.edu	37	5	140222663	140222663	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018911.2	+1	reviewed	p.G586D	0.005	56	0%	49	57.1%	-	-	benign(0.01)	tolerated(0.64)	neutral(0.004)	superfamily_Cadherin-like
PCDHA10	56139	genome.wustl.edu	37	5	140237424	140237424	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018901.2	+1	reviewed	p.D597	0.989	31	0%	28	46.4%	-	-	-	-	-	HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like
PCDHB18	54660	genome.wustl.edu	37	5	140615467	140615467	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000274705	+1	known	p.N394	0.989	208	0%	314	43.6%	-	-	-	-	-	HMMSmart_CA,PatternScan_CADHERIN_1,superfamily_Cadherin
PCDHGB1	56104	genome.wustl.edu	37	5	140730145	140730145	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018922.2	+1	reviewed	p.V106	0.000	154	0%	137	46.7%	-	-	-	-	-	HMMSmart_SM00112,HMMPfam_Cadherin_2,superfamily_Cadherin-like
NDST1	3340	genome.wustl.edu	37	5	149914445	149914445	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001543.4	+1	validated	p.D371	0.018	54	0%	36	36.1%	-	-	-	-	-	NULL
G3BP1	10146	genome.wustl.edu	37	5	151183640	151183640	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005754.2	+1	reviewed	p.A463	1.000	72	0%	96	38.5%	-	-	-	-	-	NULL
SERPINB9	5272	genome.wustl.edu	37	6	2896423	2896423	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004155.4	-1	validated	p.A57V	0.011	252	0%	274	42.7%	-	-	benign(0.003)	tolerated(1)	-	HMMPfam_Serpin,HMMSmart_SERPIN,superfamily_Prot_inh_serpin
TUBB2A	7280	genome.wustl.edu	37	6	3154175	3154175	+	Silent	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001069.2	-1	validated	p.S420	0.910	126	0%	139	39.6%	-	-	-	-	-	superfamily_Tubulin C-terminal domain-like
PHACTR1	221692	genome.wustl.edu	37	6	13206268	13206268	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_030948.1	+1	validated	p.L296I	0.991	74	0%	95	18.9%	-	-	benign(0.01)	tolerated(0.23)	neutral(0.042)	NULL
ATXN1	6310	genome.wustl.edu	37	6	16306869	16306869	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000332.3	-1	reviewed	p.A713	0.835	96	1%	89	40.4%	-	-	-	-	-	NULL
PRL	5617	genome.wustl.edu	37	6	22294811	22294811	+	Missense_Mutation	SNP	A	A	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000948.4	-1	validated	p.S11A	0.942	35	2.9%	29	20.7%	-	-	benign(0.004)	tolerated(0.79)	neutral(0.001)	NULL
DCDC2	51473	genome.wustl.edu	37	6	24178636	24178636	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_016356.3	-1	reviewed	p.L416	0.984	288	0.3%	405	45.9%	-	-	-	-	-	NULL
BTN3A1	11119	genome.wustl.edu	37	6	26405834	26405834	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007048.5	+1	validated	p.R15C	0.000	120	0%	154	48.7%	-	-	probably_damaging(0.992)	tolerated(0.18)	deleterious(0.504)	NULL
ABT1	29777	genome.wustl.edu	37	6	26598284	26598284	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_013375.2	+1	reviewed	p.T128	0.442	51	0%	72	45.8%	-	-	-	-	-	superfamily_SSF54928
OR2B2	81697	genome.wustl.edu	37	6	27879737	27879737	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_033057.2	-1	validated	p.D121Y	1.000	261	0%	331	40.8%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like
MSH5	4439	genome.wustl.edu	37	6	31721125	31721125	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_025259.5	+1	reviewed	p.R304H	1.000	200	0%	225	44.4%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_MutS_III,HMMSmart_MUTSd,superfamily_DNA_repair_MutS_domIII
ZBTB9	221504	genome.wustl.edu	37	6	33423452	33423452	+	Missense_Mutation	SNP	C	C	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152735.3	+1	validated	p.T192S	0.008	71	0%	115	49.6%	-	-	benign(0)	tolerated(0.8)	neutral(0.001)	NULL
CUL9	23113	genome.wustl.edu	37	6	43167815	43167815	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015089.2	+1	validated	p.R1102L	0.957	109	0%	134	35.8%	-	-	possibly_damaging(0.847)	tolerated(0.11)	deleterious(0.597)	superfamily_ARM repeat
PKHD1	5314	genome.wustl.edu	37	6	51875160	51875160	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_138694.3	-1	reviewed	p.P1900S	1.000	133	0%	164	23.2%	-	-	probably_damaging(1)	tolerated(0.15)	deleterious(0.741)	NULL
PGM3	5238	genome.wustl.edu	37	6	83900643	83900643	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015599.1	-1	provisional	p.T30M	0.088	157	0%	163	54%	-	-	probably_damaging(0.99)	tolerated(0.33)	neutral(0.466)	NULL
BEND3	57673	genome.wustl.edu	37	6	107390739	107390739	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001080450.2	-1	validated	p.D552	1.000	30	0%	27	33.3%	-	-	-	-	-	NULL
MICAL1	64780	genome.wustl.edu	37	6	109774946	109774947	+	Frame_Shift_Del	DEL	GA	GA	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	GA	GA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022765.3	-1	validated	p.R121fs	0.999:0.992	-	-	-	-	-	-	-	-	-	HMMPfam_FAD_binding_3,superfamily_FAD/NAD(P)-binding domain
CDC40	51362	genome.wustl.edu	37	6	110530466	110530466	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000431461	+1	known	p.A116V	0.000	69	0%	60	10%	-	-	-	-	-	NULL
AMD1	262	genome.wustl.edu	37	6	111213992	111213992	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001634.4	+1	reviewed	p.N224D	1.000	219	0.5%	271	40.2%	-	-	benign(0)	tolerated(1)	-	HMMPfam_SAM_decarbox,superfamily_S-AdenosylMet_decarbase_core
MAP7	9053	genome.wustl.edu	37	6	136682192	136682192	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003980.3	-1	reviewed	p.E551G	0.778	15	0%	14	64.3%	-	-	unknown(0)	deleterious(0.02)	-	HMMPfam_MAP7
HECA	51696	genome.wustl.edu	37	6	139487523	139487523	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_016217.2	+1	reviewed	p.C125Y	0.951	129	0.8%	178	27.5%	-	-	benign(0)	tolerated(1)	-	NULL
HIVEP2	3097	genome.wustl.edu	37	6	143092440	143092440	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006734.3	-1	provisional	p.L1146	0.090	61	0%	79	48.1%	-	-	-	-	-	NULL
TAB2	23118	genome.wustl.edu	37	6	149699613	149699613	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015093.4	+1	reviewed	p.G188C	1.000	408	0.2%	409	38.1%	-	-	possibly_damaging(0.845)	tolerated(0.05)	deleterious(0.669)	NULL
ZC3H12D	340152	genome.wustl.edu	37	6	149777858	149777858	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000458251	-1	known	p.R50*	0.014	30	0%	32	50%	-	-	-	-	-	NULL
IGF2R	3482	genome.wustl.edu	37	6	160492998	160492998	+	Nonsense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000876.2	+1	reviewed	p.W1500*	0.997	175	0%	133	42.9%	-	-	-	-	-	HMMPfam_CIMR,superfamily_Mannose 6-phosphate receptor domain
MIOS	54468	genome.wustl.edu	37	7	7612370	7612370	+	Silent	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_019005.3	+1	validated	p.V88	0.845	170	0%	221	26.2%	-	-	-	-	-	superfamily_WD40 repeat-like
DNAH11	8701	genome.wustl.edu	37	7	21603811	21603811	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003777.3	+1	reviewed	p.L330	0.004	84	0%	86	36%	-	-	-	-	-	HMMPfam_DHC_N1
DNAH11	8701	genome.wustl.edu	37	7	21784132	21784132	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003777.3	+1	reviewed	p.R2751H	1.000	261	0%	268	43.3%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	superfamily_P-loop containing nucleoside triphosphate hydrolases
STK31	56164	genome.wustl.edu	37	7	23751758	23751758	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_031414.3	+1	reviewed	p.D31N	0.998	115	0%	135	43%	-	-	benign(0)	tolerated(1)	-	HMMPfam_TUDOR
AOAH	313	genome.wustl.edu	37	7	36661365	36661365	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001637.3	-1	reviewed	p.R202W	0.999	209	0%	220	44.1%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	NULL
PKD1L1	168507	genome.wustl.edu	37	7	47886656	47886656	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_138295.2	-1	reviewed	p.G1658	0.851	52	0%	80	48.7%	-	-	-	-	-	NULL
ABCA13	154664	genome.wustl.edu	37	7	48390246	48390246	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152701.3	+1	reviewed	p.L3404P	0.005	120	0%	122	32%	-	-	benign(0.318)	-	-	NULL
RABGEF1	27342	genome.wustl.edu	37	7	66270295	66270295	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014504.2	+1	validated	p.R330H	1.000	170	0%	181	39.2%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMPfam_VPS9,HMMSmart_VPS9,superfamily_SSF109993
SEMA3C	10512	genome.wustl.edu	37	7	80546024	80546024	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006379.2	-1	validated	p.P25H	1.000	171	0%	220	10.5%	-	-	possibly_damaging(0.654)	deleterious(0)	deleterious(0.674)	superfamily_Sema
POP7	10248	genome.wustl.edu	37	7	100304521	100304521	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005837.2	+1	validated	p.R23M	1.000	34	0%	37	59.5%	-	-	probably_damaging(0.999)	deleterious(0.01)	deleterious(0.896)	NULL
DUS4L	11062	genome.wustl.edu	37	7	107216853	107216853	+	Splice_Site	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000422290	+1	known	e4-1	1.000	95	0%	91	38.5%	-	-	-	-	-	-
LAMB1	3912	genome.wustl.edu	37	7	107638831	107638831	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002291.2	-1	reviewed	p.R107H	1.000	113	0%	93	39.8%	-	-	probably_damaging(1)	deleterious(0.02)	deleterious(0.883)	HMMPfam_Laminin_N,HMMSmart_SM00136
LAMB4	22798	genome.wustl.edu	37	7	107744960	107744960	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007356.2	-1	validated	p.Q325H	0.001	131	0%	122	45.1%	-	-	benign(0)	tolerated(0.48)	neutral(0.011)	HMMPfam_Laminin_EGF,HMMSmart_SM00180,PatternScan_EGF_LAM_1,superfamily_EGF/Laminin
C7orf53	286006	genome.wustl.edu	37	7	112127072	112127072	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001134468.1	+1	validated	p.S74R	1.000	218	0%	206	23.8%	-	-	benign(0.418)	deleterious(0)	deleterious(0.580)	NULL
FSCN3	29999	genome.wustl.edu	37	7	127236393	127236393	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020369.1	+1	provisional	p.R285C	0.171	323	0%	331	38.1%	-	-	benign(0)	tolerated(0.32)	neutral(0.024)	superfamily_Actin_crosslink,HMMPfam_Fascin
SLC13A4	26266	genome.wustl.edu	37	7	135376066	135376066	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_012450.2	-1	validated	p.N442	0.000	123	0%	110	43.6%	-	-	-	-	-	HMMPfam_Na_sulph_symp
DENND2A	27147	genome.wustl.edu	37	7	140219504	140219504	+	Nonsense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015689.3	-1	validated	p.R976*	1.000	70	0%	70	42.9%	-	-	-	-	-	NULL
MGAM	8972	genome.wustl.edu	37	7	141763355	141763355	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004668.2	+1	reviewed	p.D1438	0.011	30	0%	30	46.7%	-	-	-	-	-	HMMPfam_Glyco_hydro_31
TRBV30	28557	genome.wustl.edu	37	7	142510336	142510336	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000417977	-1	known	p.Q90	0.007	22	0%	25	28%	-	-	-	-	-	HMMPfam_V-set,superfamily_SSF48726
ASIC3	9311	genome.wustl.edu	37	7	150749784	150749784	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020322.2	+1	reviewed	p.M528V	0.000	161	0%	153	13.7%	-	-	unknown(0)	-	-	NULL
INSIG1	3638	genome.wustl.edu	37	7	155099995	155099995	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_198336.2	+1	reviewed	p.P307Q	0.000	121	0.8%	112	43.8%	-	-	probably_damaging(0.968)	deleterious(0)	deleterious(0.855)	NULL
PTPRN2	5799	genome.wustl.edu	37	7	157985110	157985110	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002847.3	-1	reviewed	p.R153H	0.827	23	0%	24	33.3%	-	-	probably_damaging(0.995)	deleterious(0.01)	deleterious(0.863)	NULL
ARHGEF10	9639	genome.wustl.edu	37	8	1808128	1808128	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014629.2	+1	reviewed	p.M87V	0.000	108	0%	105	41.9%	-	-	benign(0)	tolerated(0.08)	neutral(0.300)	NULL
MTMR7	9108	genome.wustl.edu	37	8	17188770	17188770	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004686.4	-1	reviewed	p.A252T	1.000	81	0%	77	26%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMPfam_Myotub-related,superfamily_(Phosphotyrosine protein) phosphatases II
TNFRSF10D	8793	genome.wustl.edu	37	8	23012464	23012464	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003840.3	-1	reviewed	p.R60Q	0.000	64	0%	71	59.2%	-	-	benign(0.373)	tolerated(0.43)	neutral(0.133)	NULL
FZD3	7976	genome.wustl.edu	37	8	28360714	28360714	+	Missense_Mutation	SNP	A	A	G	rs61754565		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017412.2	+1	reviewed	p.M62V	1.000	117	0%	110	41.8%	-	-	benign(0.003)	tolerated(1)	-	superfamily_Frizzled cysteine-rich domain,HMMPfam_Fz,HMMSmart_SM00063
ADAM9	8754	genome.wustl.edu	37	8	38874739	38874739	+	Nonsense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003816.2	+1	reviewed	p.G138*	1.000	178	0%	164	12.8%	-	-	-	-	-	HMMPfam_Pep_M12B_propep
RP1	6101	genome.wustl.edu	37	8	55533929	55533929	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006269.1	+1	reviewed	p.A135T	0.074	28	0%	28	50%	-	-	benign(0)	tolerated(0.66)	neutral(0.003)	NULL
TGS1	96764	genome.wustl.edu	37	8	56699505	56699505	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024831.6	+1	validated	p.E350K	0.004	174	0%	152	43.4%	-	-	benign(0.002)	tolerated(0.07)	neutral(0.319)	NULL
CNBD1	168975	genome.wustl.edu	37	8	87917357	87917357	+	Missense_Mutation	SNP	A	A	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173538.2	+1	provisional	p.Q69H	0.999	53	0%	43	58.1%	-	-	probably_damaging(0.991)	tolerated(0.16)	deleterious(0.504)	NULL
OSGIN2	734	genome.wustl.edu	37	8	90937735	90937737	+	In_Frame_Del	DEL	GAG	GAG	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	GAG	GAG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001126111.1	+1	validated	p.G545in_frame_del	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	NULL
CPQ	10404	genome.wustl.edu	37	8	97797184	97797184	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_016134.2	+1	provisional	p.G20V	0.959	422	0%	404	40.1%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	NULL
SPAG1	6674	genome.wustl.edu	37	8	101174534	101174534	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003114.3	+1	reviewed	p.L9S	0.646	49	0%	58	37.9%	-	-	benign(0.05)	deleterious(0.01)	neutral(0.409)	NULL
ZFP41	286128	genome.wustl.edu	37	8	144332508	144332508	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173832.3	+1	provisional	p.H165	1.000	114	0%	111	41.4%	-	-	-	-	-	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667
GLI4	2738	genome.wustl.edu	37	8	144351679	144351679	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_138465.3	+1	validated	p.G38V	0.001	34	0%	35	51.4%	-	-	probably_damaging(1)	tolerated(0.12)	deleterious(0.760)	NULL
SH3GL2	6456	genome.wustl.edu	37	9	17789460	17789460	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003026.2	+1	validated	p.P179L	1.000	147	0%	173	41.6%	-	-	possibly_damaging(0.885)	deleterious(0.01)	deleterious(0.752)	HMMPfam_BAR,HMMSmart_SM00721
ADAMTSL1	92949	genome.wustl.edu	37	9	18639251	18639251	+	Splice_Site	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001040272.4	+1	validated	e7-1	1.000	138	0%	168	41.1%	-	-	-	-	-	-
DENND4C	55667	genome.wustl.edu	37	9	19346463	19346463	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017925.4	+1	provisional	p.S947	0.014	134	0%	156	41.7%	-	-	-	-	-	NULL
TLN1	7094	genome.wustl.edu	37	9	35698486	35698486	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006289.3	-1	reviewed	p.A2402V	1.000	25	0%	27	29.6%	-	-	probably_damaging(0.998)	deleterious(0.01)	deleterious(0.880)	HMMPfam_I_LWEQ,HMMSmart_ILWEQ,superfamily_SSF109885
FRMPD1	22844	genome.wustl.edu	37	9	37744397	37744398	+	Frame_Shift_Ins	INS	-	-	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014907.2	+1	validated	p.S791fs	0.012:0.069	-	-	-	-	-	-	-	-	-	NULL
C9orf129	445577	genome.wustl.edu	37	9	96097804	96097804	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001098808.1	-1	provisional	p.E73K	1.000	73	1.4%	86	45.3%	-	-	possibly_damaging(0.891)	deleterious(0.02)	deleterious(0.734)	NULL
KLF4	9314	genome.wustl.edu	37	9	110249444	110249444	+	Nonsense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004235.4	-1	validated	p.E377*	1.000	71	0%	62	27.4%	-	-	-	-	-	NULL
GSN	2934	genome.wustl.edu	37	9	124064372	124064372	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000177.4	+1	reviewed	p.G92	0.510	65	0%	62	53.2%	-	-	-	-	-	HMMSmart_SM00262,HMMPfam_Gelsolin,superfamily_Actin depolymerizing proteins
FPGS	2356	genome.wustl.edu	37	9	130573287	130573287	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004957.4	+1	reviewed	p.A451T	0.993	16	0%	11	45.5%	-	-	benign(0)	deleterious(0.03)	neutral(0.364)	HMMPfam_Mur_ligase_C
COQ4	51117	genome.wustl.edu	37	9	131095766	131095766	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_016035.3	+1	validated	p.L214M	1.000	39	0%	69	37.7%	-	-	probably_damaging(0.985)	tolerated(0.05)	deleterious(0.777)	HMMPfam_Coq4
LAMC3	10319	genome.wustl.edu	37	9	133917079	133917079	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006059.3	+1	reviewed	p.R447C	0.021	66	0%	57	47.4%	-	-	probably_damaging(0.998)	deleterious(0.04)	deleterious(0.823)	HMMPfam_Laminin_EGF,HMMSmart_EGF_Lam,superfamily_SSF57196
UPF2	26019	genome.wustl.edu	37	10	11990443	11990443	+	Missense_Mutation	SNP	T	T	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015542.2	-1	reviewed	p.E1033D	0.998	84	0%	103	30.1%	-	-	benign(0)	tolerated(0.67)	neutral(0.003)	NULL
PTER	9317	genome.wustl.edu	37	10	16528606	16528606	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001001484.1	+1	validated	p.H230Y	1.000	224	0%	275	41.8%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_PTE,superfamily_Metallo-dependent hydrolases
ST8SIA6	338596	genome.wustl.edu	37	10	17369027	17369027	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000440449	-1	known	p.R28*	0.289	117	0%	135	29.6%	-	-	-	-	-	HMMPfam_Glyco_transf_29
LOC645954	645954	genome.wustl.edu	37	10	31000309	31000310	+	RNA	INS	-	-	T	rs11450745	byCluster;by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	XR_017086.3	+1	model	NULL	1.000:1.000	-	-	-	-	-	-	-	-	-	-
ITGB1	3688	genome.wustl.edu	37	10	33208849	33208849	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_033667.2	-1	reviewed	p.H478R	0.995	279	0%	258	46.9%	-	-	possibly_damaging(0.661)	tolerated(0.16)	neutral(0.293)	NULL
DRGX	644168	genome.wustl.edu	37	10	50574230	50574230	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001080520.1	-1	provisional	p.A246	0.000	66	0%	54	42.6%	-	-	-	-	-	NULL
ANK3	288	genome.wustl.edu	37	10	61835608	61835608	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020987.2	-1	reviewed	p.S1677	0.997	275	0.4%	231	30.3%	-	-	-	-	-	NULL
MYPN	84665	genome.wustl.edu	37	10	69934351	69934351	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032578.2	+1	validated	p.L834	0.998	103	0%	116	44.8%	-	-	-	-	-	NULL
LRRC20	55222	genome.wustl.edu	37	10	72136224	72136224	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_207119.1	-1	validated	p.S22	0.999	112	0%	112	46.4%	-	-	-	-	-	NULL
CDH23	64072	genome.wustl.edu	37	10	73562691	73562691	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022124.5	+1	reviewed	p.P2507S	1.000	80	0%	82	48.8%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMSmart_SM00112,superfamily_Cadherin-like
PTEN	5728	genome.wustl.edu	37	10	89653796	89653798	+	In_Frame_Del	DEL	ATT	ATT	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	ATT	ATT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000371953	+1	known	p.I33in_frame_del	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	HMMSmart_SM00404,superfamily_(Phosphotyrosine protein) phosphatases II
ACTA2	59	genome.wustl.edu	37	10	90695022	90695022	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001141945.1	-1	reviewed	p.Y364	0.841	153	0%	221	32.6%	-	-	-	-	-	HMMPfam_Actin,HMMSmart_SM00268,PatternScan_ACTINS_2,superfamily_Actin-like ATPase domain
TNKS2	80351	genome.wustl.edu	37	10	93615445	93615445	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_025235.3	+1	validated	p.K996N	1.000	49	0%	58	34.5%	-	-	possibly_damaging(0.556)	deleterious(0.01)	deleterious(0.595)	HMMPfam_PARP,superfamily_SSF56399
KIF11	3832	genome.wustl.edu	37	10	94393494	94393494	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004523.3	+1	reviewed	p.M606T	0.201	136	0%	177	49.2%	-	-	benign(0.03)	tolerated(0.58)	neutral(0.007)	NULL
PIK3AP1	118788	genome.wustl.edu	37	10	98469724	98469724	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152309.2	-1	validated	p.C10	0.082	63	0%	65	58.5%	-	-	-	-	-	NULL
ANKRD2	26287	genome.wustl.edu	37	10	99338293	99338293	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020349.2	+1	validated	p.A156	0.005	7	0.000	8	0.500	-	-	-	-	-	HMMSmart_SM00248,superfamily_Ankyrin repeat
PPRC1	23082	genome.wustl.edu	37	10	103906833	103906833	+	Nonsense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015062.3	+1	reviewed	p.Q1362*	0.982	90	0%	132	12.1%	-	-	-	-	-	NULL
GPAM	57678	genome.wustl.edu	37	10	113919686	113919686	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020918.4	-1	validated	p.E629K	1.000	121	0%	123	54.5%	-	-	probably_damaging(0.995)	deleterious(0)	deleterious(0.902)	NULL
GFRA1	2674	genome.wustl.edu	37	10	118030540	118030540	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005264.4	-1	reviewed	p.S43N	1.000	45	0%	38	55.3%	-	-	probably_damaging(1)	deleterious(0.03)	deleterious(0.865)	HMMPfam_GDNF,superfamily_GDNF receptor-like (Pfam 02351)
VAX1	11023	genome.wustl.edu	37	10	118891747	118891747	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_199131.2	-1	reviewed	p.S178	0.000	30	0%	35	37.1%	-	-	-	-	-	NULL
MKI67	4288	genome.wustl.edu	37	10	129904780	129904780	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002417.4	-1	reviewed	p.T1775M	0.000	297	0%	366	29.8%	-	-	probably_damaging(1)	tolerated(0.11)	deleterious(0.772)	HMMPfam_K167R
C10orf91	170393	genome.wustl.edu	37	10	134261361	134261361	+	Silent	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173541.2	+1	validated	p.A78	0.000	35	0%	45	35.6%	-	-	-	-	-	NULL
APBB1	322	genome.wustl.edu	37	11	6422803	6422803	+	Splice_Site	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001164.2	-1	reviewed	e9+1	1.000	88	0%	104	28.8%	-	-	-	-	-	-
SPON1	10418	genome.wustl.edu	37	11	14101497	14101497	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006108.2	+1	validated	p.A202V	0.994	86	0%	86	32.6%	-	-	possibly_damaging(0.543)	deleterious(0.01)	deleterious(0.590)	NULL
SPON1	10418	genome.wustl.edu	37	11	14287139	14287139	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000310358	+1	known	p.R776H	1.000	40	0%	70	52.9%	-	-	unknown(0)	-	-	HMMPfam_TSP_1,HMMSmart_SM00209,superfamily_TSP-1 type 1 repeat
ABCC8	6833	genome.wustl.edu	37	11	17452412	17452412	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000352.3	-1	reviewed	p.P589L	1.000	164	0%	168	41.7%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_ABC_membrane,superfamily_Multidrug resistance ABC transporter MsbA N-terminal domain
NAT10	55226	genome.wustl.edu	37	11	34160759	34160759	+	Missense_Mutation	SNP	T	T	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024662.2	+1	validated	p.S745A	1.000	229	0%	189	38.6%	-	-	benign(0.28)	deleterious(0)	deleterious(0.530)	superfamily_Acyl-CoA N-acyltransferases (Nat)
TTC17	55761	genome.wustl.edu	37	11	43419565	43419565	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018259.5	+1	validated	p.H320	1.000	144	0%	132	45.5%	-	-	-	-	-	HMMPfam_TPR_1,HMMSmart_TPR,superfamily_SSF48452
GYLTL1B	120071	genome.wustl.edu	37	11	45948422	45948422	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152312.3	+1	validated	p.R442Q	1.000	24	0%	19	47.4%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	NULL
SPRYD5	84767	genome.wustl.edu	37	11	55652996	55652996	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032681.3	+1	validated	p.G31V	1.000	132	0%	154	54.5%	-	-	probably_damaging(1)	tolerated(0.07)	deleterious(0.819)	HMMSmart_SM00184,PatternScan_ZF_RING_1,HMMPfam_zf-C3HC4,superfamily_RING/U-box
TNKS1BP1	85456	genome.wustl.edu	37	11	57088122	57088122	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_033396.2	-1	validated	p.L53	1.000	15	0%	22	54.5%	-	-	-	-	-	NULL
DPF2	5977	genome.wustl.edu	37	11	65111216	65111216	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006268.3	+1	reviewed	p.R156W	1.000	27	0%	29	51.7%	-	-	benign(0.001)	tolerated(0.07)	neutral(0.319)	NULL
SUV420H1	51111	genome.wustl.edu	37	11	67939116	67939116	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000323599	-1	known	p.R228K	1.000	84	0%	89	36%	-	-	-	-	-	superfamily_SET domain
USP35	57558	genome.wustl.edu	37	11	77921120	77921120	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020798.2	+1	provisional	p.T740I	0.000	186	0%	187	45.5%	-	-	unknown(0)	deleterious(0.02)	-	HMMPfam_UCH,superfamily_Cysteine proteinases
ODZ4	26011	genome.wustl.edu	37	11	78412983	78412983	+	Nonsense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001098816.2	-1	validated	p.R1559*	1.000	99	0%	94	24.5%	-	-	-	-	-	HMMPfam_NHL,superfamily_SSF101898,superfamily_TolB_C
GRM5	2915	genome.wustl.edu	37	11	88300813	88300815	+	In_Frame_Del	DEL	TCT	TCT	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	TCT	TCT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001143831.2	-1	reviewed	p.K679in_frame_del	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	HMMPfam_7tm_3
C11orf87	399947	genome.wustl.edu	37	11	109294373	109294373	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_207645.3	+1	validated	p.A5V	0.998	33	0%	22	36.4%	-	-	probably_damaging(0.959)	tolerated(1)	neutral(0.403)	NULL
APOA1	335	genome.wustl.edu	37	11	116707771	116707771	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000039.1	-1	reviewed	p.S49N	0.021	49	0%	43	46.5%	-	-	benign(0.155)	tolerated(0.08)	neutral(0.314)	superfamily_SSF47162
TBCEL	219899	genome.wustl.edu	37	11	120957679	120957679	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001130047.1	+1	validated	p.M383I	1.000	198	0%	193	46.1%	-	-	benign(0.002)	tolerated(0.15)	neutral(0.241)	superfamily_SSF54236
TECTA	7007	genome.wustl.edu	37	11	121023729	121023729	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005422.2	+1	reviewed	p.N1415	0.968	62	0%	72	16.7%	-	-	-	-	-	superfamily_Serine proterase inhibitors,HMMSmart_SM00181,PatternScan_EGF_2,HMMPfam_TIL
SRPR	6734	genome.wustl.edu	37	11	126136085	126136085	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003139.3	-1	reviewed	p.P310L	1.000	162	0%	215	18.6%	-	-	benign(0.018)	tolerated(0.12)	neutral(0.261)	NULL
OPCML	4978	genome.wustl.edu	37	11	132812851	132812851	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002545.3	-1	reviewed	p.T46M	1.000	47	0%	33	33.3%	-	-	probably_damaging(1)	deleterious(0.04)	deleterious(0.849)	HMMSmart_SM00409,HMMPfam_V-set,superfamily_Immunoglobulin
NCAPD3	23310	genome.wustl.edu	37	11	134051035	134051035	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015261.2	-1	validated	p.E832	0.037	52	0%	47	53.2%	-	-	-	-	-	superfamily_ARM-type_fold
B4GALNT3	283358	genome.wustl.edu	37	12	665930	665930	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173593.3	+1	validated	p.R760C	0.002	16	0%	18	44.4%	-	-	possibly_damaging(0.906)	deleterious(0.01)	deleterious(0.765)	NULL
CCND2	894	genome.wustl.edu	37	12	4409088	4409088	+	Nonsense_Mutation	SNP	C	C	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001759.3	+1	validated	p.Y261*	1.000	134	0%	133	51.1%	-	-	-	-	-	HMMPfam_Cyclin_C
CD9	928	genome.wustl.edu	37	12	6341821	6341821	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001769.2	+1	reviewed	p.G67S	0.995	8	0.000	8	0.500	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_Tetraspannin,PatternScan_TM4_1
NCAPD2	9918	genome.wustl.edu	37	12	6640140	6640140	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014865.3	+1	validated	p.P1340S	0.945	120	0%	120	41.7%	-	-	probably_damaging(1)	tolerated(0.15)	deleterious(0.741)	NULL
OLR1	4973	genome.wustl.edu	37	12	10319465	10319465	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002543.3	-1	reviewed	p.Q90	0.000	206	0%	293	27.6%	-	-	-	-	-	NULL
HEBP1	50865	genome.wustl.edu	37	12	13128270	13128270	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015987.3	-1	reviewed	p.R181H	0.999	119	0%	157	40.8%	-	-	possibly_damaging(0.48)	deleterious(0.01)	deleterious(0.565)	HMMPfam_SOUL
KRAS	3845	genome.wustl.edu	37	12	25380275	25380275	+	Missense_Mutation	SNP	T	T	G	rs17851045	byCluster	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_033360.2	-1	reviewed	p.Q61H	1.000	59	0%	96	43.8%	-	-	benign(0.006)	deleterious(0.01)	neutral(0.406)	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases
PKP2	5318	genome.wustl.edu	37	12	32975444	32975446	+	In_Frame_Del	DEL	TTG	TTG	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	TTG	TTG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004572.3	-1	reviewed	p.N642in_frame_del	0.920:0.919:0.688	-	-	-	-	-	-	-	-	-	superfamily_ARM repeat
MLL2	8085	genome.wustl.edu	37	12	49416428	49416428	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003482.3	-1	validated	p.G5428D	1.000	230	0%	247	42.1%	-	-	unknown(0)	-	-	HMMPfam_SET,HMMSmart_SM00317,superfamily_SET domain
SLC4A8	9498	genome.wustl.edu	37	12	51888848	51888848	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001039960.1	+1	validated	p.L963	0.297	171	0%	205	46.3%	-	-	-	-	-	NULL
KRT83	3889	genome.wustl.edu	37	12	52711516	52711516	+	Silent	SNP	G	G	A	rs186866078	by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002282.3	-1	reviewed	p.N233	0.030	221	0%	308	48.1%	-	-	-	-	-	HMMPfam_Filament
NCKAP1L	3071	genome.wustl.edu	37	12	54902244	54902244	+	Silent	SNP	G	G	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005337.4	+1	reviewed	p.L145	1.000	366	0%	434	48.8%	-	-	-	-	-	HMMPfam_Nckap1
MYL6B	140465	genome.wustl.edu	37	12	56549385	56549385	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000405661	+1	known	p.G177C	0.959	60	0%	58	32.8%	-	-	-	-	-	NULL
IFNG	3458	genome.wustl.edu	37	12	68553345	68553345	+	Silent	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000619.2	-1	reviewed	p.G17	0.033	41	0%	46	45.7%	-	-	-	-	-	HMMPfam_IFN-gamma
MDM1	56890	genome.wustl.edu	37	12	68709980	68709980	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017440.4	-1	reviewed	p.T353	0.954	69	0%	88	44.3%	-	-	-	-	-	NULL
ACSS3	79611	genome.wustl.edu	37	12	81537007	81537007	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024560.2	+1	validated	p.G301D	1.000	137	0%	139	20.1%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_AMP-binding,PatternScan_AMP_BINDING,superfamily_Acetyl-CoA synthetase-like
DAO	1610	genome.wustl.edu	37	12	109278864	109278864	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001917.4	+1	reviewed	p.Q28K	0.248	85	0%	103	62.1%	-	-	benign(0)	tolerated(0.8)	neutral(0.001)	HMMPfam_DAO,superfamily_Nucleotide-binding domain
ATP2A2	488	genome.wustl.edu	37	12	110778612	110778612	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_170665.3	+1	reviewed	p.R637H	1.000	81	0%	113	44.2%	-	-	probably_damaging(0.98)	deleterious(0.03)	deleterious(0.788)	HMMPfam_Hydrolase,superfamily_HAD-like,superfamily_Calcium ATPase transmembrane domain M
PLBD2	196463	genome.wustl.edu	37	12	113824842	113824842	+	Silent	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173542.3	+1	validated	p.R463	0.982	93	0%	110	43.6%	-	-	-	-	-	HMMPfam_Phospholip_B
NOS1	4842	genome.wustl.edu	37	12	117718666	117718666	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000620.2	-1	reviewed	p.A463V	1.000	52	0%	72	41.7%	-	-	probably_damaging(0.996)	tolerated(0.15)	deleterious(0.703)	HMMPfam_NO_synthase,superfamily_Nitric oxide (NO) synthase oxygenase domain
KSR2	283455	genome.wustl.edu	37	12	117909047	117909047	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_173598.4	-1	validated	p.G858	0.999	84	0%	102	46.1%	-	-	-	-	-	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase
DNAH10	196385	genome.wustl.edu	37	12	124323046	124323046	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_207437.3	+1	validated	p.C1531Y	1.000	117	0%	108	49.1%	-	-	probably_damaging(0.999)	deleterious(0.02)	deleterious(0.873)	HMMPfam_DHC_N2
EP400	57634	genome.wustl.edu	37	12	132514661	132514661	+	Silent	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015409.3	+1	validated	p.T1903	1.000	88	0%	93	33.3%	-	-	-	-	-	HMMPfam_Helicase_C,HMMSmart_HELICc,superfamily_SSF52540
MTMR6	9107	genome.wustl.edu	37	13	25832812	25832812	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004685.3	-1	validated	p.R249G	1.000	54	0%	71	42.3%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMPfam_Myotub-related,superfamily_(Phosphotyrosine protein) phosphatases II
FREM2	341640	genome.wustl.edu	37	13	39262222	39262222	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_207361.4	+1	reviewed	p.G247	0.000	47	0%	26	53.8%	-	-	-	-	-	NULL
KIAA0564	23078	genome.wustl.edu	37	13	42357946	42357946	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015058.1	-1	validated	p.F754L	1.000	105	0%	102	41.2%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	superfamily_P-loop containing nucleoside triphosphate hydrolases
KLF12	11278	genome.wustl.edu	37	13	74289618	74289618	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007249.4	-1	validated	p.R305L	1.000	105	0%	123	43.9%	-	-	benign(0.254)	tolerated(0.15)	neutral(0.267)	NULL
TBC1D4	9882	genome.wustl.edu	37	13	75873473	75873473	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014832.2	-1	validated	p.S1050L	1.000	102	0%	97	18.6%	-	-	possibly_damaging(0.928)	tolerated(0.21)	neutral(0.419)	HMMPfam_TBC,HMMSmart_SM00164,superfamily_Ypt/Rab-GAP domain of gyp1p
FAM70B	348013	genome.wustl.edu	37	13	114471915	114471915	+	Silent	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000375348	+1	known	p.T62	0.001	35	0%	38	39.5%	-	-	-	-	-	NULL
OR4K2	390431	genome.wustl.edu	37	14	20344740	20344740	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001005501.1	+1	provisional	p.H105R	0.688	346	0%	395	39.7%	-	-	probably_damaging(0.999)	deleterious(0)	deleterious(0.935)	HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like
PRMT5	10419	genome.wustl.edu	37	14	23393582	23393582	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006109.3	-1	validated	p.A366T	1.000	159	0%	249	10.8%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_PRMT5,superfamily_S-adenosyl-L-methionine-dependent methyltransferases
MIPOL1	145282	genome.wustl.edu	37	14	37736237	37736237	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_138731.5	+1	validated	p.M38I	0.002	90	1.1%	86	19.8%	-	-	possibly_damaging(0.574)	tolerated(0.62)	neutral(0.201)	NULL
MGAT2	4247	genome.wustl.edu	37	14	50089047	50089047	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002408.3	+1	reviewed	p.T354I	1.000	181	0%	182	12.1%	-	-	possibly_damaging(0.948)	deleterious(0)	deleterious(0.836)	HMMPfam_MGAT2,superfamily_Nucleotide-diphospho-sugar transferases
GALNTL1	57452	genome.wustl.edu	37	14	69818849	69818849	+	Silent	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020692.2	+1	validated	p.A547	0.591	84	0%	69	10.1%	-	-	-	-	-	HMMPfam_Ricin_B_lectin,HMMSmart_SM00458,superfamily_Ricin B-like lectins
PNMA1	9240	genome.wustl.edu	37	14	74179647	74179647	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006029.4	-1	validated	p.A232	0.853	90	0%	107	46.7%	-	-	-	-	-	NULL
ISM2	145501	genome.wustl.edu	37	14	77942165	77942165	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_199296.2	-1	reviewed	p.D497Y	0.000	45	0%	35	54.3%	-	-	possibly_damaging(0.467)	tolerated(0.07)	deleterious(0.473)	HMMPfam_AMOP,HMMSmart_SM00723
PTPN21	11099	genome.wustl.edu	37	14	88936361	88936361	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007039.3	-1	reviewed	p.A969T	1.000	54	0%	61	42.6%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMPfam_Y_phosphatase,HMMSmart_SM00194,superfamily_(Phosphotyrosine protein) phosphatases II
C14orf102	55051	genome.wustl.edu	37	14	90778853	90778853	+	Missense_Mutation	SNP	G	G	A	rs187130409	by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017970.2	-1	validated	p.R148C	0.001	210	0%	238	47.1%	-	-	probably_damaging(0.994)	deleterious(0.04)	deleterious(0.801)	NULL
EVL	51466	genome.wustl.edu	37	14	100604092	100604092	+	Frame_Shift_Del	DEL	A	A	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_016337.2	+1	validated	p.K350fs	0.968	-	-	-	-	-	-	-	-	-	NULL
CYFIP1	23191	genome.wustl.edu	37	15	22997828	22997828	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014608.2	+1	validated	p.A1025V	1.000	196	0%	179	18.4%	-	-	probably_damaging(1)	tolerated(0.14)	deleterious(0.750)	HMMPfam_FragX_IP
RYR3	6263	genome.wustl.edu	37	15	34018675	34018675	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001036.3	+1	validated	p.S2334N	1.000	25	0%	18	66.7%	-	-	probably_damaging(0.998)	-	-	NULL
BAHD1	22893	genome.wustl.edu	37	15	40752064	40752064	+	Silent	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014952.3	+1	validated	p.G467	0.976	23	0%	26	61.5%	-	-	-	-	-	NULL
FAM82A2	55177	genome.wustl.edu	37	15	41030190	41030190	+	Missense_Mutation	SNP	G	G	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018145.1	-1	provisional	p.H366Q	1.000	268	0%	341	39%	-	-	probably_damaging(0.964)	deleterious(0.03)	deleterious(0.771)	superfamily_TPR-like
ATP8B4	79895	genome.wustl.edu	37	15	50271881	50271881	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024837.2	-1	validated	p.G323R	1.000	338	0%	365	41.9%	-	-	probably_damaging(0.995)	deleterious(0)	deleterious(0.902)	HMMPfam_E1-E2_ATPase,superfamily_SSF81665
LEO1	123169	genome.wustl.edu	37	15	52251016	52251016	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_138792.2	-1	provisional	p.D390N	1.000	153	0%	185	42.7%	-	-	probably_damaging(0.958)	deleterious(0)	deleterious(0.846)	HMMPfam_Leo1
MYO5C	55930	genome.wustl.edu	37	15	52567772	52567772	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018728.2	-1	validated	p.N198S	1.000	125	0.8%	164	48.2%	-	-	possibly_damaging(0.547)	tolerated(1)	neutral(0.185)	HMMPfam_Myosin_head,HMMSmart_SM00242,superfamily_P-loop containing nucleoside triphosphate hydrolases
HERC1	8925	genome.wustl.edu	37	15	63986307	63986307	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003922.3	-1	reviewed	p.L1844	1.000	60	0%	70	47.1%	-	-	-	-	-	NULL
SLC24A1	9187	genome.wustl.edu	37	15	65917240	65917240	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004727.2	+1	validated	p.S274	0.000	91	0%	155	52.3%	-	-	-	-	-	NULL
MEGF11	84465	genome.wustl.edu	37	15	66249927	66249927	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032445.2	-1	validated	p.C415	0.984	32	0%	26	30.8%	-	-	-	-	-	HMMSmart_SM00180,HMMSmart_SM00181
MPI	4351	genome.wustl.edu	37	15	75189853	75189853	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002435.1	+1	reviewed	p.V352I	1.000	78	0%	80	48.7%	-	-	benign(0.082)	tolerated(0.3)	neutral(0.035)	HMMPfam_PMI_typeI,superfamily_RmlC-like cupins
ENSG00000214677	0	genome.wustl.edu	37	15	76031447	76031447	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000398772	-1	known	p.G171V	1.000	13	0%	13	38.5%	-	-	-	-	-	NULL
CHRNB4	1143	genome.wustl.edu	37	15	78917546	78917546	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000750.3	-1	validated	p.G476W	1.000	147	0%	158	33.5%	-	-	probably_damaging(1)	deleterious(0.03)	deleterious(0.865)	HMMPfam_Neur_chan_memb,superfamily_Neu_channel_TM
IL16	3603	genome.wustl.edu	37	15	81598375	81598375	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_172217.3	+1	reviewed	p.R1183C	1.000	127	0%	150	34.7%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_PDZ,HMMSmart_SM00228,superfamily_PDZ domain-like
ANPEP	290	genome.wustl.edu	37	15	90340839	90340839	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001150.2	-1	reviewed	p.M708I	1.000	189	0%	182	10.4%	-	-	possibly_damaging(0.695)	deleterious(0.02)	deleterious(0.632)	NULL
NAA60	79903	genome.wustl.edu	37	16	3533572	3533572	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001083600.1	+1	validated	p.G183S	1.000	48	0%	50	48%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	superfamily_Acyl_CoA_acyltransferase
PPL	5493	genome.wustl.edu	37	16	4934260	4934260	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002705.4	-1	reviewed	p.L1466	1.000	138	0%	112	33%	-	-	-	-	-	NULL
PRM2	5620	genome.wustl.edu	37	16	11369990	11369990	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002762.2	-1	validated	p.R80C	0.011	26	0%	19	36.8%	-	-	benign(0.134)	-	-	HMMPfam_Protamine_P2
PDXDC1	23042	genome.wustl.edu	37	16	15129951	15129951	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015027.2	+1	validated	p.L729S	1.000	111	0%	144	42.4%	-	-	possibly_damaging(0.527)	deleterious(0.01)	deleterious(0.584)	NULL
XYLT1	64131	genome.wustl.edu	37	16	17352862	17352862	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022166.3	-1	reviewed	p.R299Q	0.992	121	0%	118	10.2%	-	-	probably_damaging(0.979)	tolerated(0.08)	deleterious(0.722)	NULL
ENSG00000245868	0	genome.wustl.edu	37	16	23490063	23490063	+	RNA	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000498959	+1	novel	NULL	0.005	63	0%	44	25%	-	-	-	-	-	-
RRN3P2	653390	genome.wustl.edu	37	16	29110458	29110458	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000427965	+1	known	p.W375R	0.991	103	1%	117	21.4%	-	-	benign(0)	tolerated(1)	-	HMMPfam_RRN3
KIF22	3835	genome.wustl.edu	37	16	29809773	29809773	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007317.1	+1	reviewed	p.L115	1.000	89	0%	68	50%	-	-	-	-	-	HMMPfam_Kinesin,HMMSmart_KISc,superfamily_SSF52540
ITGAX	3687	genome.wustl.edu	37	16	31374634	31374634	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000887.3	+1	reviewed	p.R550Q	0.000	102	0%	119	47.1%	-	-	benign(0.405)	tolerated(0.47)	neutral(0.142)	HMMPfam_FG-GAP,HMMSmart_Int_alpha,superfamily_SSF69318
ZNF267	10308	genome.wustl.edu	37	16	31927101	31927101	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003414.4	+1	validated	p.R511W	0.989	169	0%	173	42.8%	-	-	probably_damaging(0.971)	tolerated(0.08)	deleterious(0.713)	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers
ORC6	23594	genome.wustl.edu	37	16	46724956	46724956	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014321.2	+1	reviewed	p.A40V	0.694	82	0%	108	48.1%	-	-	possibly_damaging(0.901)	tolerated(0.28)	neutral(0.388)	HMMPfam_ORC6
CES5A	221223	genome.wustl.edu	37	16	55890355	55890355	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001143685.1	-1	validated	p.K353	0.062	178	0.6%	182	45.6%	-	-	-	-	-	HMMPfam_COesterase,superfamily_alpha/beta-Hydrolases
SLC12A3	6559	genome.wustl.edu	37	16	56899291	56899291	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000339.2	+1	reviewed	p.S48	1.000	73	0%	77	49.4%	-	-	-	-	-	NULL
CPNE2	221184	genome.wustl.edu	37	16	57149427	57149427	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152727.4	+1	reviewed	p.L134	0.992	38	0%	42	57.1%	-	-	-	-	-	superfamily_C2_CaLB
FAM65A	79567	genome.wustl.edu	37	16	67572665	67572665	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000428437	+1	known	p.R60C	0.956	70	1.4%	68	55.9%	-	-	-	-	-	NULL
SLC12A4	6560	genome.wustl.edu	37	16	67979272	67979272	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005072.4	-1	validated	p.P1011L	1.000	38	0%	29	44.8%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	NULL
AARS	16	genome.wustl.edu	37	16	70295027	70295027	+	Nonsense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001605.2	-1	reviewed	p.R569*	1.000	51	0%	45	46.7%	-	-	-	-	-	HMMPfam_tRNA-synt_2c
FUK	197258	genome.wustl.edu	37	16	70501303	70501303	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_145059.2	+1	reviewed	p.A171T	1.000	4	0.000	10	0.400	-	-	benign(0.004)	tolerated(0.6)	neutral(0.004)	HMMPfam_Fucokinase
HYDIN	54768	genome.wustl.edu	37	16	71065649	71065649	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032821.2	-1	validated	p.G901R	0.988	118	0%	107	40.2%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	NULL
ZFHX3	463	genome.wustl.edu	37	16	72984792	72984792	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006885.3	-1	reviewed	p.G931D	1.000	77	0%	78	39.7%	-	-	unknown(0)	-	-	NULL
CHST5	23563	genome.wustl.edu	37	16	75563388	75563388	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024533.3	-1	validated	p.A299T	1.000	27	0%	28	17.9%	-	-	benign(0.018)	tolerated(0.12)	neutral(0.261)	HMMPfam_Sulfotransfer_1,superfamily_P-loop containing nucleoside triphosphate hydrolases
JPH3	57338	genome.wustl.edu	37	16	87678382	87678382	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020655.2	+1	reviewed	p.G301S	1.000	24	0%	25	36%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_MORN,HMMSmart_SM00698,superfamily_Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain
BANP	54971	genome.wustl.edu	37	16	88039856	88039856	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_079837.2	+1	reviewed	p.T175A	1.000	35	0%	53	39.6%	-	-	probably_damaging(0.975)	deleterious(0)	deleterious(0.861)	NULL
ZC3H18	124245	genome.wustl.edu	37	16	88675400	88675400	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_144604.3	+1	validated	p.G383R	1.000	172	0.6%	171	33.3%	-	-	unknown(0)	deleterious(0.01)	-	NULL
SERPINF1	5176	genome.wustl.edu	37	17	1678426	1678426	+	Missense_Mutation	SNP	A	A	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002615.4	+1	validated	p.R240W	0.000	62	0%	81	46.9%	-	-	probably_damaging(0.992)	deleterious(0.02)	deleterious(0.831)	HMMPfam_Serpin,HMMSmart_SM00093,superfamily_Serpins
PELP1	27043	genome.wustl.edu	37	17	4576196	4576196	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014389.2	-1	validated	p.S697L	0.276	35	0%	31	29%	-	-	unknown(0)	deleterious(0)	-	NULL
DNAH2	146754	genome.wustl.edu	37	17	7708650	7708650	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020877.2	+1	validated	p.M3127I	1.000	127	0%	128	21.9%	-	-	benign(0.079)	deleterious(0.02)	neutral(0.389)	NULL
GAS7	8522	genome.wustl.edu	37	17	9820563	9820563	+	Silent	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_201433.1	-1	reviewed	p.P471	0.030	90	0%	79	41.8%	-	-	-	-	-	NULL
MYH8	4626	genome.wustl.edu	37	17	10307665	10307665	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002472.2	-1	reviewed	p.L890	1.000	76	0%	99	43.4%	-	-	-	-	-	NULL
MYH1	4619	genome.wustl.edu	37	17	10400729	10400729	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005963.3	-1	reviewed	p.A1469V	1.000	82	0%	79	36.7%	-	-	unknown(0)	tolerated(0.12)	-	HMMPfam_Myosin_tail_1
FAM83G	644815	genome.wustl.edu	37	17	18874816	18874816	+	Silent	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001039999.2	-1	validated	p.T776	0.000	43	0%	26	19.2%	-	-	-	-	-	NULL
SLC35G3	146861	genome.wustl.edu	37	17	33520477	33520477	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152462.2	-1	validated	p.A284T	1.000	145	0%	174	29.3%	-	-	benign(0)	tolerated(0.55)	neutral(0.007)	superfamily_Multidrug resistance efflux transporter EmrE
PIGW	284098	genome.wustl.edu	37	17	34893921	34893922	+	Frame_Shift_Del	DEL	TA	TA	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	TA	TA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_178517.3	+1	validated	p.M326fs	0.000:0.097	-	-	-	-	-	-	-	-	-	HMMPfam_GWT1
MED24	9862	genome.wustl.edu	37	17	38189362	38189362	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014815.3	-1	reviewed	p.T257A	1.000	55	0%	45	46.7%	-	-	possibly_damaging(0.858)	tolerated(0.19)	neutral(0.381)	NULL
KRTAP9-9	81870	genome.wustl.edu	37	17	39411660	39411660	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_030975.2	+1	reviewed	p.C8Y	1.000	274	0%	391	39.9%	-	-	unknown(0)	tolerated(0.07)	-	HMMPfam_Keratin_B2
KRTAP9-9	81870	genome.wustl.edu	37	17	39412141	39412141	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_030975.2	+1	reviewed	p.C148	0.998	390	0%	526	26.8%	-	-	-	-	-	HMMPfam_Keratin_B2
DHX58	79132	genome.wustl.edu	37	17	40262917	40262917	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024119.2	-1	validated	p.V129M	0.785	81	0%	80	43.8%	-	-	possibly_damaging(0.939)	deleterious(0)	deleterious(0.829)	HMMPfam_DEAD,HMMSmart_DEXDc,superfamily_SSF52540
NAGS	162417	genome.wustl.edu	37	17	42085860	42085862	+	In_Frame_Del	DEL	TCT	TCT	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	TCT	TCT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_153006.2	+1	reviewed	p.F501in_frame_del	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	HMMPfam_DUF619
TBKBP1	9755	genome.wustl.edu	37	17	45773581	45773581	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014726.2	+1	validated	p.D35N	1.000	49	0%	78	26.9%	-	-	probably_damaging(0.979)	deleterious(0)	deleterious(0.867)	NULL
CACNA1G	8913	genome.wustl.edu	37	17	48650469	48650469	+	Missense_Mutation	SNP	A	A	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018896.3	+1	validated	p.I379L	1.000	17	0%	15	40%	-	-	probably_damaging(0.995)	tolerated(0.09)	deleterious(0.754)	HMMPfam_Ion_trans,superfamily_Voltage-gated potassium channels
CACNA1G	8913	genome.wustl.edu	37	17	48669123	48669123	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018896.3	+1	validated	p.G888D	1.000	92	0%	91	16.5%	-	-	probably_damaging(0.986)	deleterious(0)	deleterious(0.879)	HMMPfam_Ion_trans,superfamily_Voltage-gated potassium channels
TANC2	26115	genome.wustl.edu	37	17	61432681	61432681	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_025185.3	+1	validated	p.H764Y	1.000	101	0%	118	48.3%	-	-	probably_damaging(0.999)	deleterious(0)	deleterious(0.935)	NULL
ACE	1636	genome.wustl.edu	37	17	61564379	61564379	+	Silent	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000789.2	+1	reviewed	p.T750	0.004	25	0%	32	46.9%	-	-	-	-	-	"HMMPfam_Peptidase_M2,superfamily_Metalloproteases (""zincins"") catalytic domain"
DDX42	11325	genome.wustl.edu	37	17	61890661	61890661	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007372.2	+1	reviewed	p.T583	0.409	156	0%	156	44.9%	-	-	-	-	-	HMMPfam_Helicase_C,HMMSmart_SM00490,superfamily_P-loop containing nucleoside triphosphate hydrolases
POLG2	11232	genome.wustl.edu	37	17	62486940	62486940	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_007215.3	-1	reviewed	p.M314I	0.939	147	0%	160	27.5%	-	-	benign(0.156)	tolerated(0.2)	neutral(0.063)	superfamily_SSF55681
PRKCA	5578	genome.wustl.edu	37	17	64770120	64770120	+	Frame_Shift_Del	DEL	C	C	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002737.2	+1	reviewed	p.P514fs	1.000	-	-	-	-	-	-	-	-	-	HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase
DNAI2	64446	genome.wustl.edu	37	17	72305490	72305490	+	Missense_Mutation	SNP	T	T	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_023036.4	+1	reviewed	p.F437Y	0.976	30	0%	28	17.9%	-	-	benign(0)	tolerated(0.7)	neutral(0.002)	superfamily_WD40 repeat-like
CD300LF	146722	genome.wustl.edu	37	17	72694595	72694595	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_139018.3	-1	validated	p.L158F	0.304	25	0%	30	50%	-	-	unknown(0)	deleterious(0)	-	NULL
EVPL	2125	genome.wustl.edu	37	17	74004680	74004680	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001988.2	-1	validated	p.R1536W	0.987	79	0%	100	48%	-	-	probably_damaging(1)	tolerated(0.05)	deleterious(0.845)	NULL
DNAH17	8632	genome.wustl.edu	37	17	76446338	76446338	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000389840	-1	known	p.K3666E	1.000	25	0%	15	53.3%	-	-	possibly_damaging(0.945)	tolerated(0.46)	neutral(0.402)	NULL
ENGASE	64772	genome.wustl.edu	37	17	77076311	77076311	+	Silent	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001042573.1	+1	validated	p.N196	0.000	23	0%	31	19.4%	-	-	-	-	-	HMMPfam_Glyco_hydro_85
C17orf70	80233	genome.wustl.edu	37	17	79516258	79516258	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_025161.5	-1	validated	p.L308	0.004	13	0%	14	35.7%	-	-	-	-	-	NULL
MYOM1	8736	genome.wustl.edu	37	18	3075754	3075754	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003803.3	-1	reviewed	p.D1552N	1.000	24	0%	36	52.8%	-	-	benign(0.41)	deleterious(0.01)	deleterious(0.538)	NULL
TGIF1	7050	genome.wustl.edu	37	18	3457801	3457802	+	Frame_Shift_Del	DEL	AC	AC	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	AC	AC					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_170695.2	+1	reviewed	p.Q358fs	0.961:0.995	-	-	-	-	-	-	-	-	-	NULL
PPP4R1	9989	genome.wustl.edu	37	18	9549316	9549316	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001042388.1	-1	validated	p.C856	1.000	136	0%	135	43.7%	-	-	-	-	-	superfamily_ARM repeat
MOCOS	55034	genome.wustl.edu	37	18	33795824	33795824	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017947.2	+1	validated	p.A561T	0.000	130	0%	140	46.4%	-	-	benign(0)	tolerated(0.64)	neutral(0.003)	NULL
NFATC1	4772	genome.wustl.edu	37	18	77246358	77246358	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_172387.1	+1	reviewed	p.A722T	0.024	30	0%	32	62.5%	-	-	benign(0)	tolerated(0.77)	neutral(0.001)	NULL
HCN2	610	genome.wustl.edu	37	19	608076	608076	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001194.3	+1	validated	p.T444I	1.000	9	0.000	11	0.364	-	-	possibly_damaging(0.76)	deleterious(0.01)	deleterious(0.687)	HMMPfam_Ion_trans,superfamily_SSF81324
ABCA7	10347	genome.wustl.edu	37	19	1061871	1061871	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_019112.3	+1	reviewed	p.V1852M	0.686	3	0.000	8	0.625	-	-	benign(0.394)	tolerated(0.15)	neutral(0.367)	HMMPfam_ABC_tran,HMMSmart_SM00382,superfamily_P-loop containing nucleoside triphosphate hydrolases
DENND1C	79958	genome.wustl.edu	37	19	6470326	6470326	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024898.2	-1	validated	p.V448I	0.950	34	0%	21	28.6%	-	-	probably_damaging(0.995)	deleterious(0.01)	deleterious(0.863)	NULL
MUC16	94025	genome.wustl.edu	37	19	9077331	9077331	+	Missense_Mutation	SNP	G	G	T	rs143304016	by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024690.2	-1	validated	p.P3372H	0.000	706	0%	703	44.1%	-	-	unknown(0)	-	-	NULL
ZNF763	284390	genome.wustl.edu	37	19	12089469	12089469	+	Nonsense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001012753.1	+1	validated	p.R247*	0.000	176	0%	242	40.9%	-	-	-	-	-	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667
FBXW9	84261	genome.wustl.edu	37	19	12801980	12801980	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032301.2	-1	validated	p.A295S	1.000	68	0%	77	28.6%	-	-	possibly_damaging(0.795)	tolerated(0.35)	neutral(0.319)	superfamily_WD40_like
OR7A10	390892	genome.wustl.edu	37	19	14952485	14952485	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001005190.1	-1	provisional	p.V69I	0.001	244	0%	362	46.4%	-	-	benign(0.081)	tolerated(0.16)	neutral(0.066)	HMMPfam_7tm_1,superfamily_SSF81321
RASAL3	64926	genome.wustl.edu	37	19	15572100	15572100	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_022904.1	-1	validated	p.R158Q	0.724	15	0%	35	48.6%	-	-	probably_damaging(0.97)	tolerated(0.07)	deleterious(0.732)	NULL
ZNF91	7644	genome.wustl.edu	37	19	23545000	23545000	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003430.2	-1	validated	p.A261T	0.047	390	0.3%	506	13.8%	-	-	benign(0.003)	tolerated(1)	-	superfamily_C2H2 and C2HC zinc fingers
MAG	4099	genome.wustl.edu	37	19	35790481	35790481	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002361.2	+1	reviewed	p.P147L	0.565	12	0%	17	41.2%	-	-	possibly_damaging(0.461)	tolerated(0.06)	deleterious(0.474)	HMMPfam_C2-set_2,superfamily_SSF48726
KIRREL2	84063	genome.wustl.edu	37	19	36353881	36353881	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_199180.2	+1	validated	p.S556	0.037	8	0.000	15	0.533	-	-	-	-	-	NULL
RYR1	6261	genome.wustl.edu	37	19	38990636	38990636	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000540.2	+1	reviewed	p.R2435C	1.000	32	0%	31	67.7%	-	-	probably_damaging(1)	-	-	NULL
CIC	23152	genome.wustl.edu	37	19	42791587	42791587	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015125.3	+1	validated	p.R190C	1.000	125	0%	73	38.4%	-	-	probably_damaging(0.979)	deleterious(0.01)	deleterious(0.828)	superfamily_HMG-box
PVRL2	5819	genome.wustl.edu	37	19	45377679	45377679	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001042724.1	+1	reviewed	p.C329Y	0.999	154	0%	106	40.6%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMSmart_SM00409,HMMPfam_ig,superfamily_Immunoglobulin
CLPTM1	1209	genome.wustl.edu	37	19	45493682	45493682	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001294.1	+1	provisional	p.L388M	1.000	103	0%	94	39.4%	-	-	probably_damaging(0.968)	tolerated(0.36)	neutral(0.430)	HMMPfam_CLPTM1
SYNGR4	23546	genome.wustl.edu	37	19	48878931	48878931	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_012451.2	+1	reviewed	p.S131	0.000	48	0%	75	46.7%	-	-	-	-	-	HMMPfam_MARVEL
GRWD1	83743	genome.wustl.edu	37	19	48954462	48954462	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_031485.3	+1	validated	p.K333E	1.000	46	0%	40	50%	-	-	possibly_damaging(0.95)	tolerated(0.08)	deleterious(0.694)	HMMSmart_SM00320,superfamily_WD40 repeat-like,PatternScan_WD_REPEATS_1,HMMPfam_WD40
ZNF525	170958	genome.wustl.edu	37	19	53884007	53884009	+	In_Frame_Del	DEL	TCA	TCA	-	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	TCA	TCA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000474037	+1	known	p.S60in_frame_del	0.100:0.099:0.091	-	-	-	-	-	-	-	-	-	HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352)
KIR2DL4	3805	genome.wustl.edu	37	19	55325391	55325391	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001080770.1	+1	reviewed	p.S285I	0.000	296	0%	366	19.9%	-	-	benign(0.001)	deleterious(0)	neutral(0.445)	NULL
LOC646698	646698	genome.wustl.edu	37	19	56756741	56756741	+	Missense_Mutation	SNP	G	G	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	XM_001725568.1	+1	model	p.A176P	0.001	52	0%	53	35.8%	-	-	-	-	-	NULL
ZSCAN4	201516	genome.wustl.edu	37	19	58187704	58187704	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_152677.2	+1	validated	p.R64I	0.007	125	0%	172	41.9%	-	-	probably_damaging(0.998)	tolerated(0.09)	deleterious(0.771)	HMMPfam_SCAN
ZNF814	730051	genome.wustl.edu	37	19	58384588	58384588	+	Missense_Mutation	SNP	A	A	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001144989.1	-1	validated	p.F724I	0.000	142	0%	199	46.7%	-	-	benign(0.141)	tolerated(0.58)	neutral(0.017)	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers
SNPH	9751	genome.wustl.edu	37	20	1286361	1286361	+	Missense_Mutation	SNP	C	C	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014723.2	+1	reviewed	p.P383H	0.609	5	0.000	12	0.583	-	-	possibly_damaging(0.631)	tolerated(0.06)	deleterious(0.543)	NULL
SIRPB2	284759	genome.wustl.edu	37	20	1471988	1471988	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001122962.1	-1	validated	p.S6	0.005	22	0%	19	57.9%	-	-	-	-	-	NULL
TGM6	343641	genome.wustl.edu	37	20	2375953	2375953	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_198994.2	+1	validated	p.V99I	0.004	62	0%	60	48.3%	-	-	benign(0.005)	tolerated(0.44)	neutral(0.013)	HMMPfam_Transglut_N,superfamily_E set domains
DEFB118	117285	genome.wustl.edu	37	20	29960960	29960960	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_054112.1	+1	provisional	p.H120R	0.000	184	0%	194	49.5%	-	-	benign(0.171)	deleterious(0)	neutral(0.460)	NULL
TTLL9	164395	genome.wustl.edu	37	20	30496476	30496476	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001008409.2	+1	provisional	p.R97W	0.999	16	0%	29	31%	-	-	probably_damaging(1)	deleterious(0)	deleterious(0.945)	HMMPfam_TTL
XKR7	343702	genome.wustl.edu	37	20	30584922	30584922	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001011718.1	+1	provisional	p.A468T	0.996	25	0%	35	42.9%	-	-	benign(0.424)	tolerated(0.17)	neutral(0.197)	NULL
BPIFB6	128859	genome.wustl.edu	37	20	31628108	31628108	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_174897.2	+1	validated	p.A376T	0.761	47	0%	62	21%	-	-	benign(0.001)	tolerated(0.58)	neutral(0.005)	HMMPfam_LBP_BPI_CETP_C,HMMSmart_BPI2,superfamily_Bactericidal_perm-incr_a/b_dom
ZNF341	84905	genome.wustl.edu	37	20	32349699	32349699	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032819.3	+1	validated	p.A347T	1.000	150	0%	207	25.6%	-	-	benign(0.156)	tolerated(0.38)	neutral(0.032)	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667
RBL1	5933	genome.wustl.edu	37	20	35724211	35724211	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_002895.2	-1	reviewed	p.D41N	1.000	10	0%	14	42.9%	-	-	benign(0.004)	tolerated(0.9)	-	NULL
PPP1R16B	26051	genome.wustl.edu	37	20	37547220	37547220	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015568.2	+1	reviewed	p.V539I	0.998	45	0%	53	17%	-	-	possibly_damaging(0.815)	tolerated(0.42)	neutral(0.322)	NULL
SEMG2	6407	genome.wustl.edu	37	20	43850637	43850637	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003008.2	+1	reviewed	p.H122Y	0.000	307	0%	303	47.5%	-	-	possibly_damaging(0.797)	deleterious(0.01)	deleterious(0.705)	HMMPfam_Semenogelin
SLC9A8	23315	genome.wustl.edu	37	20	48497525	48497525	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015266.1	+1	validated	p.R408Q	1.000	347	0%	354	46.9%	-	-	probably_damaging(1)	deleterious(0.01)	deleterious(0.905)	HMMPfam_Na_H_Exchanger
BCAS1	8537	genome.wustl.edu	37	20	52645024	52645024	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003657.2	-1	reviewed	p.D210	0.000	418	0.2%	461	45.8%	-	-	-	-	-	NULL
SLC5A3	6526	genome.wustl.edu	37	21	35467997	35467997	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_006933.4	+1	validated	p.G167D	1.000	206	0%	210	30.5%	-	-	benign(0.196)	deleterious(0.02)	neutral(0.402)	HMMPfam_SSF,PatternScan_NA_SOLUT_SYMP_1
WRB	7485	genome.wustl.edu	37	21	40763744	40763744	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_004627.4	+1	reviewed	p.V106	0.788	106	0%	90	34.4%	-	-	-	-	-	HMMPfam_CHD5
RIPK4	54101	genome.wustl.edu	37	21	43161264	43161264	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_020639.2	-1	reviewed	p.L697	0.039	44	0%	41	22%	-	-	-	-	-	HMMPfam_Ank,HMMSmart_ANK,superfamily_ANK
PWP2	5822	genome.wustl.edu	37	21	45535193	45535193	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000456705	+1	known	p.P140L	0.053	68	0%	56	28.6%	-	-	unknown(0)	-	-	NULL
MCM3AP	8888	genome.wustl.edu	37	21	47704816	47704816	+	Nonsense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003906.3	-1	reviewed	p.Q129*	0.000	76	0%	91	42.9%	-	-	-	-	-	NULL
C21orf58	54058	genome.wustl.edu	37	21	47721985	47721986	+	In_Frame_Ins	INS	-	-	TGG	rs71318063	byCluster;by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000291691	-1	known	p.300in_frame_insH	0.000:0.001	-	-	-	-	-	-	-	-	-	NULL
LOC100287161	100287161	genome.wustl.edu	37	22	24656788	24656788	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	XM_002343792.1	-1	model	p.S101	0.870	21	0%	20	35%	-	-	-	-	-	HMMPfam_RhoGAP,HMMSmart_SM00324,superfamily_GTPase activation domain GAP
ZNRF3	84133	genome.wustl.edu	37	22	29445298	29445298	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_032173.2	+1	validated	p.A277T	1.000	47	0%	63	57.1%	-	-	probably_damaging(0.955)	tolerated(0.1)	deleterious(0.685)	NULL
TNRC6B	23112	genome.wustl.edu	37	22	40662362	40662362	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015088.2	+1	validated	p.G710R	1.000	84	0%	80	32.5%	-	-	probably_damaging(0.998)	deleterious(0)	deleterious(0.919)	NULL
TNRC6B	23112	genome.wustl.edu	37	22	40697177	40697179	+	In_Frame_Del	DEL	GCA	GCA	-	rs71764365	byCluster;by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	GCA	GCA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_015088.2	+1	validated	p.Q1214in_frame_del	1.000:1.000:1.000	-	-	-	-	-	-	-	-	-	NULL
TCF20	6942	genome.wustl.edu	37	22	42610471	42610471	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005650.1	-1	reviewed	p.A281T	0.998	425	0%	468	43.2%	-	-	probably_damaging(0.98)	deleterious(0.01)	deleterious(0.830)	NULL
NCAPH2	29781	genome.wustl.edu	37	22	50961624	50961624	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000395701	+1	known	p.G569E	0.000	9	0.000	14	0.643	-	-	benign(0.29)	tolerated(1)	neutral(0.089)	HMMPfam_DUF1032
KIR2DL5B	553128	genome.wustl.edu	37	GL000209.1	67542	67542	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	ENST00000400851	+1	known	p.S340I	NULL	277	0%	296	41.2%	-	-	benign(0.025)	deleterious(0)	neutral(0.446)	NULL
PHKA2	5256	genome.wustl.edu	37	X	18970629	18970629	+	Nonsense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000292.2	-1	reviewed	p.Q90*	1.000	142	0%	155	41.3%	-	-	-	-	-	HMMPfam_PHK_AB,superfamily_Six-hairpin glycosidases
PDK3	5165	genome.wustl.edu	37	X	24552116	24552116	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001142386.2	+1	reviewed	p.T383M	0.982	107	0%	116	10.3%	-	-	benign(0.356)	tolerated(0.13)	neutral(0.365)	NULL
CASK	8573	genome.wustl.edu	37	X	41379784	41379784	+	Silent	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003688.3	-1	reviewed	p.F885	1.000	153	0%	170	41.2%	-	-	-	-	-	HMMSmart_GuKc,superfamily_SSF52540
ERAS	3266	genome.wustl.edu	37	X	48687822	48687822	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_181532.2	+1	provisional	p.A97T	0.614	57	0%	32	37.5%	-	-	benign(0.184)	deleterious(0)	neutral(0.462)	HMMSmart_RAS,HMMPfam_Ras,superfamily_SSF52540
HUWE1	10075	genome.wustl.edu	37	X	53607838	53607838	+	Missense_Mutation	SNP	T	T	C	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_031407.4	-1	reviewed	p.N1890S	1.000	43	0%	42	16.7%	-	-	benign(0)	tolerated(0.13)	neutral(0.253)	superfamily_ARM repeat
APEX2	27301	genome.wustl.edu	37	X	55028778	55028778	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_014481.2	+1	reviewed	p.C112	1.000	56	0%	75	10.7%	-	-	-	-	-	HMMPfam_Exo_endo_phos,superfamily_Exo_endo_phos
LAS1L	81887	genome.wustl.edu	37	X	64753514	64753514	+	Missense_Mutation	SNP	A	A	G	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_031206.4	-1	validated	p.L113P	1.000	331	0%	398	46.2%	-	-	probably_damaging(0.999)	deleterious(0.01)	deleterious(0.896)	HMMPfam_Las1
ZMYM3	9203	genome.wustl.edu	37	X	70468138	70468138	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_005096.3	-1	reviewed	p.R617C	0.998	44	0%	56	57.1%	-	-	probably_damaging(0.988)	deleterious(0)	deleterious(0.882)	HMMPfam_zf-FCS,HMMSmart_SM00746
NONO	4841	genome.wustl.edu	37	X	70517254	70517254	+	Missense_Mutation	SNP	G	G	A	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_001145408.1	+1	reviewed	p.R324Q	1.000	26	0%	20	60%	-	-	probably_damaging(0.998)	tolerated(0.1)	deleterious(0.761)	NULL
ACRC	93953	genome.wustl.edu	37	X	70814209	70814209	+	Missense_Mutation	SNP	G	G	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_052957.4	+1	validated	p.G57C	0.001	126	0%	117	43.6%	-	-	unknown(0)	deleterious(0)	-	NULL
NAP1L2	4674	genome.wustl.edu	37	X	72434247	72434247	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_021963.2	-1	reviewed	p.G28R	0.012	147	0%	200	19%	-	-	benign(0.002)	deleterious(0)	neutral(0.445)	NULL
BRWD3	254065	genome.wustl.edu	37	X	79932558	79932558	+	Missense_Mutation	SNP	T	T	A	rs181617490	by1000genomes	TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_153252.4	-1	reviewed	p.K1653N	1.000	545	0.2%	683	42%	-	-	probably_damaging(0.988)	deleterious(0)	deleterious(0.882)	NULL
PABPC5	140886	genome.wustl.edu	37	X	90690585	90690585	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_080832.2	+1	reviewed	p.S3	0.996	54	0%	50	32%	-	-	-	-	-	NULL
CXorf57	55086	genome.wustl.edu	37	X	105865979	105865979	+	Nonsense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_018015.5	+1	validated	p.R248*	0.991	163	0.6%	205	48.3%	-	-	-	-	-	superfamily_Nucleic acid-binding proteins
MORC4	79710	genome.wustl.edu	37	X	106229258	106229258	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_024657.4	-1	reviewed	p.A161T	1.000	344	0.3%	337	42.7%	-	-	probably_damaging(0.987)	tolerated(0.17)	deleterious(0.495)	superfamily_ATP_bd_ATPase
AVPR2	554	genome.wustl.edu	37	X	153171375	153171375	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_000054.4	+1	reviewed	p.R139C	0.998	63	0%	51	47.1%	-	-	probably_damaging(0.999)	tolerated(0.17)	deleterious(0.549)	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_Family A G protein-coupled receptor-like
NAA10	8260	genome.wustl.edu	37	X	153195637	153195637	+	Missense_Mutation	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_003491.2	-1	provisional	p.V171M	0.008	40	0%	44	22.7%	-	-	benign(0.186)	tolerated(0.29)	neutral(0.046)	NULL
PLXNA3	55558	genome.wustl.edu	37	X	153689949	153689949	+	Silent	SNP	C	C	T	novel		TCGA-AP-A0LG-01A-11W-A062-09	TCGA-AP-A0LG-10A-01W-A062-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	ce187e7f-447e-48ca-87f4-55d616a5b67e	e1f4872f-2c1a-445f-8a50-8f3a3a554a9f	NM_017514.3	+1	reviewed	p.L369	1.000	30	0%	18	22.2%	-	-	-	-	-	HMMPfam_Sema,HMMSmart_Sema,superfamily_Sema
