Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KIF12	113220	broad.mit.edu	37	9	116858369	116858369	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr9:116858369A>G	uc004bif.3	-	5	681	c.443T>C	c.(442-444)cTt>cCt	p.L148P	KIF12_uc004big.3_Non-coding_Transcript	NM_138424	NP_612433	Q96FN5	KIF12_HUMAN	Homo sapiens kinesin family member 12 (KIF12), mRNA.	281	Kinesin-motor.				microtubule-based movement	cytoplasm|microtubule	ATP binding|microtubule motor activity			breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(5)|prostate(1)|skin(1)|urinary_tract(1)	17						GTTAGCCTCAAGCATCAGCTC	0.627000													6	116					0	0	1	0	0
C9orf3	84909	broad.mit.edu	37	9	97843033	97843033	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr9:97843033A>G	uc004ava.3	+	13	2425	c.2290A>G	c.(2290-2292)Agt>Ggt	p.S764G	C9orf3_uc004auy.3_Missense_Mutation_p.S665G|C9orf3_uc004auz.1_Missense_Mutation_p.S665G|C9orf3_uc011luj.2_Missense_Mutation_p.S126G|C9orf3_uc011luk.2_Missense_Mutation_p.S105G	NM_001193329	NP_001180258	Q8N6M6	AMPO_HUMAN	Homo sapiens chromosome 9 open reading frame 3 (C9orf3), transcript variant 1, mRNA.	764					leukotriene biosynthetic process|proteolysis	cytoplasm	aminopeptidase activity|metallopeptidase activity|zinc ion binding			cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(12)|ovary(1)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	23				OV - Ovarian serous cystadenocarcinoma(323;0.000275)		AGCCTACAAAAGTGTGGAGAG	0.512000													24	65					0	0	1	0	0
ELK3	2004	broad.mit.edu	37	12	96641092	96641092	+	Silent	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr12:96641092C>T	uc001teo.1	+	2	861	c.582C>T	c.(580-582)gtC>gtT	p.V194V		NM_005230	NP_005221	P41970	ELK3_HUMAN	Homo sapiens ELK3, ETS-domain protein (SRF accessory protein 2) (ELK3), mRNA.	194					negative regulation of transcription, DNA-dependent|signal transduction	mitochondrion	protein binding|purine-rich negative regulatory element binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity			breast(2)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(4)|liver(1)|lung(5)|ovary(2)|prostate(1)|stomach(2)	20	all_cancers(2;0.00173)					ACAAGCACGTCACCAGGCCGG	0.607000													7	76					0	0	1	0	0
GLRA1	2741	broad.mit.edu	37	5	151239422	151239422	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr5:151239422C>T	uc003lut.3	-	3	687	c.400G>A	c.(400-402)Gcc>Acc	p.A134T	GLRA1_uc003lur.3_Missense_Mutation_p.A134T|GLRA1_uc003lus.3_Missense_Mutation_p.A51T	NM_001146040	NP_001139512	P23415	GLRA1_HUMAN	Homo sapiens glycine receptor, alpha 1 (GLRA1), transcript variant 1, mRNA.	134					muscle contraction|negative regulation of transmission of nerve impulse|neuropeptide signaling pathway|positive regulation of acrosome reaction|regulation of membrane potential|startle response	cell junction|chloride channel complex|integral to plasma membrane|intracellular membrane-bounded organelle|postsynaptic membrane	extracellular-glycine-gated chloride channel activity|glycine binding|protein binding|receptor activity|taurine binding|transmitter-gated ion channel activity			breast(1)|central_nervous_system(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(6)|ovary(1)|prostate(1)|skin(3)|urinary_tract(1)	23		all_hematologic(541;0.0341)|Medulloblastoma(196;0.0912)	Kidney(363;0.000171)|KIRC - Kidney renal clear cell carcinoma(527;0.000785)		Desflurane(DB01189)|Enflurane(DB00228)|Ethanol(DB00898)|Glycine(DB00145)|Halothane(DB01159)|Isoflurane(DB00753)|Methoxyflurane(DB01028)|Sevoflurane(DB01236)	TGGAAGTGGGCCCCCTTCTCG	0.522000													25	64					0	0	1	0	0
SLC4A2	6522	broad.mit.edu	37	7	150761318	150761318	+	Silent	SNP	G	G	A	rs142515597	byFrequency	TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr7:150761318G>A	uc022apz.1	+	2	1121	c.81G>A	c.(79-81)acG>acA	p.T27T	SLC4A2_uc003wit.4_Silent_p.T27T|SLC4A2_uc011kve.2_Silent_p.T18T|SLC4A2_uc003wiu.4_Silent_p.T13T	NM_001199692	NP_001186621	P04920	B3A2_HUMAN	Homo sapiens solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (SLC4A2), transcript variant 2, mRNA.	27	Pro-rich.				bicarbonate transport	integral to membrane|membrane fraction	inorganic anion exchanger activity			NS(1)|central_nervous_system(2)|endometrium(3)|kidney(1)|large_intestine(2)|liver(2)|lung(14)|prostate(3)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	33			OV - Ovarian serous cystadenocarcinoma(82;0.0121)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)		GCCCTGGGACGCCTGGGTTCC	0.622000													20	58					0	0	1	0	0
PRAMEF12	390999	broad.mit.edu	37	1	12836145	12836145	+	Missense_Mutation	SNP	C	C	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:12836145C>G	uc001aui.3	+	1	774	c.747C>G	c.(745-747)gaC>gaG	p.D249E		NM_001080830	NP_001074299	O95522	PRA12_HUMAN	Homo sapiens PRAME family member 12 (PRAMEF12), mRNA.	249										NS(2)|central_nervous_system(1)|cervix(1)|endometrium(2)|large_intestine(3)|lung(9)|ovary(3)|skin(1)|urinary_tract(1)	23	Ovarian(185;0.249)	Renal(390;0.000469)|Lung NSC(185;0.00143)|all_lung(284;0.00181)|Colorectal(325;0.00215)|Breast(348;0.0042)|Myeloproliferative disorder(586;0.0393)|Hepatocellular(190;0.0623)|Ovarian(437;0.0731)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00818)|Colorectal(212;5.04e-06)|Kidney(185;4.99e-05)|KIRC - Kidney renal clear cell carcinoma(229;0.000198)|COAD - Colon adenocarcinoma(227;0.000245)|BRCA - Breast invasive adenocarcinoma(304;0.000295)|STAD - Stomach adenocarcinoma(313;0.0072)|READ - Rectum adenocarcinoma(331;0.0649)		TTCCCCTAGACAGGAAGGAGC	0.498000													22	105					0	0	1	0	0
USP3	9960	broad.mit.edu	37	15	63852135	63852135	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr15:63852135A>G	uc002amf.3	+	6	742	c.613A>G	c.(613-615)Aca>Gca	p.T205A	USP3_uc010uii.1_Intron|USP3_uc002amg.3_Missense_Mutation_p.T120A|USP3_uc002amh.3_Missense_Mutation_p.T183A|USP3_uc010uij.2_Missense_Mutation_p.T161A|USP3_uc010uik.2_Intron|USP3_uc010bgs.3_Missense_Mutation_p.T188A|USP3_uc002ami.3_Missense_Mutation_p.T36A	NM_006537	NP_006528	Q9Y6I4	UBP3_HUMAN	Homo sapiens ubiquitin specific peptidase 3 (USP3), mRNA.	205					DNA repair|histone deubiquitination|mitotic cell cycle|regulation of protein stability|ubiquitin-dependent protein catabolic process	nuclear chromatin	histone binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|zinc ion binding			endometrium(3)|large_intestine(7)|lung(4)	14				GBM - Glioblastoma multiforme(80;0.0187)		AGGAAGGCGGACATACCACAC	0.413000													5	22					0	0	1	0	0
RAB4B	53916	broad.mit.edu	37	19	41289852	41289852	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:41289852C>T	uc002opd.2	+	4	459	c.302C>T	c.(301-303)gCc>gTc	p.A101V	RAB4B_uc002opc.2_Non-coding_Transcript|RAB4B_uc002ope.2_Intron|EGLN2_uc010ehd.3_5'UTR|RAB4B_uc002opf.2_Missense_Mutation_p.A127V	NM_016154	NP_057238	P61018	RAB4B_HUMAN	Homo sapiens RAB4B, member RAS oncogene family (RAB4B), mRNA.	101					protein transport|small GTPase mediated signal transduction|vesicle-mediated transport	intracellular|plasma membrane	GTP binding|GTPase activity			endometrium(2)|kidney(3)|large_intestine(3)|lung(1)|skin(1)|upper_aerodigestive_tract(1)	11			LUSC - Lung squamous cell carcinoma(20;0.000219)|Lung(22;0.000959)			TCACTGGCTGCCTGGCTGACG	0.642000													15	36					0	0	1	0	0
ZNF101	94039	broad.mit.edu	37	19	19790542	19790542	+	Silent	SNP	T	T	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:19790542T>C	uc002nni.2	+	3	854	c.744T>C	c.(742-744)acT>acC	p.T248T	ZNF101_uc010ecg.2_Silent_p.T128T|ZNF101_uc002nnj.2_Silent_p.T128T	NM_033204	NP_149981	Q8IZC7	ZN101_HUMAN	Homo sapiens zinc finger protein 101 (ZNF101), mRNA.	248					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|endometrium(1)|kidney(1)|large_intestine(6)|lung(4)|ovary(2)|prostate(1)	17						GAACTCACACTGGAGAAAAAC	0.383000													6	23					0	0	1	0	0
CAT	847	broad.mit.edu	37	11	34474685	34474685	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr11:34474685A>G	uc001mvm.3	+	4	618	c.529A>G	c.(529-531)Aag>Gag	p.K177E	CAT_uc009ykc.1_Non-coding_Transcript	NM_001752	NP_001743	P04040	CATA_HUMAN	Homo sapiens catalase (CAT), mRNA.	177					UV protection|hydrogen peroxide catabolic process|negative regulation of apoptosis|positive regulation of cell division|protein tetramerization|purine base metabolic process|purine nucleotide catabolic process	peroxisomal matrix|peroxisomal membrane	NADP binding|catalase activity|heme binding|protein homodimerization activity			breast(1)|cervix(2)|endometrium(3)|kidney(2)|large_intestine(6)|lung(5)|ovary(2)|pancreas(1)|stomach(1)|urinary_tract(3)	26		Lung NSC(402;2.76e-08)|Acute lymphoblastic leukemia(5;0.00143)|all_hematologic(20;0.0116)|Melanoma(852;0.027)		BRCA - Breast invasive adenocarcinoma(625;0.000995)	Fomepizole(DB01213)	gacacatctgaaggatccgga	0.398000													7	23					0	0	1	0	0
ZNF326	284695	broad.mit.edu	37	1	90473286	90473286	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:90473286A>G	uc001dnq.2	+	4	731	c.592A>G	c.(592-594)Aca>Gca	p.T198A	ZNF326_uc009wda.1_Missense_Mutation_p.T109A|ZNF326_uc001dnr.2_Intron	NM_182976	NP_892021	Q5BKZ1	ZN326_HUMAN	Homo sapiens zinc finger protein 326 (ZNF326), transcript variant 1, mRNA.	198	Gly-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nuclear matrix	DNA binding			central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(12)|lung(7)|ovary(1)	25		all_lung(203;0.0116)|Lung NSC(277;0.0417)		all cancers(265;0.00728)|Epithelial(280;0.0265)		AGGACCATCAACAGGCAGAGG	0.463000													7	51					0	0	1	0	0
TSGA10	80705	broad.mit.edu	37	2	99725896	99725896	+	Nonsense_Mutation	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr2:99725896G>A	uc002szg.4	-	3	635	c.7C>T	c.(7-9)Cga>Tga	p.R3*	TSGA10_uc002szh.4_Nonsense_Mutation_p.R3*|TSGA10_uc002szi.4_Nonsense_Mutation_p.R3*|TSGA10_uc010fin.1_Nonsense_Mutation_p.R3*|TSGA10_uc010yvn.1_Nonsense_Mutation_p.R3*	NM_182911	NP_878915	Q9BZW7	TSG10_HUMAN	Homo sapiens testis specific, 10 (TSGA10), transcript variant 2, mRNA.	3					spermatogenesis	cytoplasm|nuclear membrane				NS(2)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(8)|lung(10)|ovary(1)|prostate(2)|upper_aerodigestive_tract(1)	34						GACCTACTTCGCATCATCTTT	0.393000													9	52					0	0	1	0	0
SYTL1	84958	broad.mit.edu	37	1	27674032	27674032	+	Silent	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:27674032G>A	uc001bnw.2	+	2	509	c.312G>A	c.(310-312)gcG>gcA	p.A104A	SYTL1_uc001bnv.2_Silent_p.A104A|SYTL1_uc001bnx.2_Silent_p.A104A|SYTL1_uc009vsv.2_Silent_p.A104A	NM_001193308	NP_001180237	Q8IYJ3	SYTL1_HUMAN	Homo sapiens synaptotagmin-like 1 (SYTL1), transcript variant 1, mRNA.	104					exocytosis|intracellular protein transport	extrinsic to plasma membrane|melanosome|soluble fraction	Rab GTPase binding|neurexin binding			NS(1)|large_intestine(4)|lung(5)|ovary(1)|urinary_tract(1)	12		Colorectal(325;0.000147)|all_lung(284;0.000366)|Lung NSC(340;0.000548)|Renal(390;0.00211)|Breast(348;0.0115)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0908)|all_neural(195;0.0966)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0416)|OV - Ovarian serous cystadenocarcinoma(117;1.5e-28)|Colorectal(126;1.24e-08)|COAD - Colon adenocarcinoma(152;1.7e-06)|BRCA - Breast invasive adenocarcinoma(304;0.0013)|KIRC - Kidney renal clear cell carcinoma(1967;0.00158)|STAD - Stomach adenocarcinoma(196;0.00303)|READ - Rectum adenocarcinoma(331;0.0419)		TTGTCCGAGCGTCTATGCGCA	0.632000													19	53					0	0	1	0	0
CDH4	1002	broad.mit.edu	37	20	60448832	60448832	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr20:60448832C>T	uc002ybn.2	+	6	1014	c.926C>T	c.(925-927)aCg>aTg	p.T309M	CDH4_uc002ybr.2_Missense_Mutation_p.T272M|CDH4_uc002ybp.2_Missense_Mutation_p.T235M	NM_001794	NP_001785	P55283	CADH4_HUMAN	Homo sapiens cadherin 4, type 1, R-cadherin (retinal) (CDH4), transcript variant 1, mRNA.	309	Cadherin 2.				adherens junction organization|cell junction assembly		calcium ion binding			NS(2)|breast(2)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(17)|liver(2)|lung(25)|ovary(2)|prostate(1)|skin(7)|upper_aerodigestive_tract(1)|urinary_tract(1)	74			BRCA - Breast invasive adenocarcinoma(19;2.36e-08)			GACAGCACCACGGCCAACGGG	0.602000													26	73					0	0	1	0	0
DYNC1H1	1778	broad.mit.edu	37	14	102482730	102482730	+	Silent	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr14:102482730C>T	uc001yks.2	+	36	7682	c.7518C>T	c.(7516-7518)agC>agT	p.S2506S	DYNC1H1_uc001ykt.1_5'UTR	NM_001376	NP_001367	Q14204	DYHC1_HUMAN	Homo sapiens dynein, cytoplasmic 1, heavy chain 1 (DYNC1H1), mRNA.	2506					G2/M transition of mitotic cell cycle|cytoplasmic mRNA processing body assembly|microtubule-based movement|mitotic spindle organization|stress granule assembly|transport	Golgi apparatus|centrosome|cytoplasmic dynein complex|cytosol|microtubule	ATP binding|ATPase activity, coupled|microtubule motor activity|protein binding			NS(1)|biliary_tract(1)|breast(4)|central_nervous_system(5)|cervix(1)|endometrium(21)|haematopoietic_and_lymphoid_tissue(3)|kidney(10)|large_intestine(28)|lung(60)|ovary(9)|pancreas(1)|prostate(6)|skin(7)|stomach(3)|upper_aerodigestive_tract(4)|urinary_tract(2)	166						CTGGAGACAGCCGGCTAAAAA	0.418000													4	56					0	0	1	0	0
SZT2	23334	broad.mit.edu	37	1	43906957	43906957	+	Missense_Mutation	SNP	A	A	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:43906957A>T	uc001cjk.2	+	51	7330	c.4720A>T	c.(4720-4722)Act>Tct	p.T1574S		NM_015284	NP_056099	Q5T011	SZT2_HUMAN	Homo sapiens seizure threshold 2 homolog (mouse) (SZT2), mRNA.	2473						peroxisome				NS(2)|breast(9)|central_nervous_system(1)|endometrium(17)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(19)|lung(39)|ovary(4)|pancreas(3)|prostate(4)|skin(2)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(3)	113						GCCAGAAGACACTCGGGGCCG	0.552000													39	131					0	0	1	0	0
ANAPC5	51433	broad.mit.edu	37	12	121766164	121766164	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr12:121766164A>G	uc001uag.3	-	9	1381	c.1259T>C	c.(1258-1260)aTc>aCc	p.I420T	ANAPC5_uc010szu.2_Missense_Mutation_p.I86T|ANAPC5_uc001uae.3_5'UTR|ANAPC5_uc010szv.2_Missense_Mutation_p.I22T|ANAPC5_uc001uaf.3_Non-coding_Transcript|ANAPC5_uc001uah.3_Missense_Mutation_p.I308T	NM_016237	NP_057321	Q9UJX4	APC5_HUMAN	Homo sapiens anaphase promoting complex subunit 5 (ANAPC5), transcript variant 1, mRNA.	420					G2/M transition of mitotic cell cycle|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell division|mitotic anaphase|mitotic cell cycle spindle assembly checkpoint|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination	anaphase-promoting complex|cytosol|nucleoplasm	protein phosphatase binding|ubiquitin-protein ligase activity			breast(6)|endometrium(3)|kidney(3)|large_intestine(5)|lung(10)|prostate(1)|skin(3)	31	all_neural(191;0.0684)|Medulloblastoma(191;0.0922)					TGCGATGCTGATATCGATGAG	0.547000													11	36					0	0	1	0	0
LOC650368	650368	broad.mit.edu	37	11	3427759	3427759	+	RNA	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr11:3427759C>T	uc010qxs.1	+	8		c.752C>T			LOC650368_uc001lxy.2_Non-coding_Transcript					Homo sapiens asparagine-linked glycosylation 1-like pseudogene (LOC650368), non-coding RNA.																		TGTCTGCACACGTCCTGCAGT	0.612000													4	46					0	0	1	0	0
ITGAX	3687	broad.mit.edu	37	16	31372440	31372440	+	Silent	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr16:31372440G>A	uc002ebt.3	+	8	985	c.918G>A	c.(916-918)tcG>tcA	p.S306S	ITGAX_uc002ebu.1_Silent_p.S306S|ITGAX_uc010vfk.1_5'Flank	NM_000887	NP_000878	P20702	ITAX_HUMAN	Homo sapiens integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), mRNA.	306	VWFA.				blood coagulation|cell adhesion|integrin-mediated signaling pathway|leukocyte migration|organ morphogenesis	integrin complex	protein binding|receptor activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(8)|lung(42)|ovary(2)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	77						ACATTGCATCGAAGCCCTCCC	0.363000													30	104					0	0	1	0	0
COBRA1	25920	broad.mit.edu	37	9	140161398	140161398	+	Missense_Mutation	SNP	G	G	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr9:140161398G>C	uc004cmm.4	+	8	1301	c.1098G>C	c.(1096-1098)gaG>gaC	p.E366D		NM_015456	NP_056271	Q8WX92	NELFB_HUMAN	Homo sapiens cofactor of BRCA1 (COBRA1), mRNA.	366					negative regulation of transcription, DNA-dependent|positive regulation of viral transcription|transcription elongation from RNA polymerase II promoter|viral reproduction	cytoplasm|nucleoplasm	protein binding			endometrium(2)|large_intestine(5)|lung(5)|skin(3)|upper_aerodigestive_tract(1)	16	all_cancers(76;0.0926)		STAD - Stomach adenocarcinoma(284;0.137)	OV - Ovarian serous cystadenocarcinoma(145;9.42e-05)|Epithelial(140;0.000766)		CCTCGTAGGAGGTAGAGCTCA	0.642000													8	35					0	0	1	0	0
ZNF626	199777	broad.mit.edu	37	19	20828569	20828569	+	Missense_Mutation	SNP	C	C	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:20828569C>A	uc002npb.1	-	2	297	c.147G>T	c.(145-147)aaG>aaT	p.K49N	ZNF626_uc002npc.1_Intron|ZNF626_uc002npd.1_Missense_Mutation_p.K49N	NM_001076675	NP_001070143	Q68DY1	ZN626_HUMAN	Homo sapiens zinc finger protein 626 (ZNF626), transcript variant 1, mRNA.	49	KRAB.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(1)|lung(3)|skin(1)	6						TCAGGTCTGGCTTAGAAACAG	0.378000													10	37					0	0	1	0	0
P2RX5	5026	broad.mit.edu	37	17	3593952	3593952	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr17:3593952G>A	uc002fwi.3	-	3	782	c.383C>T	c.(382-384)gCg>gTg	p.A128V	P2RX5_uc002fwd.3_Non-coding_Transcript|P2RX5_uc010vrx.2_Missense_Mutation_p.A68V|P2RX5_uc002fwk.3_Missense_Mutation_p.A128V|P2RX5_uc002fwj.3_Missense_Mutation_p.A104V|P2RX5_uc002fwl.3_Missense_Mutation_p.A104V|P2RX5_uc002fwm.2_Missense_Mutation_p.A128V	NM_002561	NP_002552	Q93086	P2RX5_HUMAN	Homo sapiens purinergic receptor P2X, ligand-gated ion channel, 5 (P2RX5), transcript variant 1, mRNA.	128					nervous system development|positive regulation of calcium ion transport into cytosol|positive regulation of calcium-mediated signaling	integral to plasma membrane	ATP binding|extracellular ATP-gated cation channel activity|purinergic nucleotide receptor activity			endometrium(1)|large_intestine(2)|lung(5)|ovary(2)|upper_aerodigestive_tract(1)	11						CTTGGAGCACGCGCCATCAGG	0.637000													14	39					0	0	1	0	0
SULT1C3	442038	broad.mit.edu	37	2	108863658	108863658	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr2:108863658A>G	uc010ywo.2	+	0	8	c.8A>G	c.(7-9)aAg>aGg	p.K3R		NM_001008743	NP_001008743	Q6IMI6	ST1C3_HUMAN	Homo sapiens sulfotransferase family, cytosolic, 1C, member 3 (SULT1C3), mRNA.	3						cytoplasm	alcohol sulfotransferase activity			breast(1)|kidney(1)|large_intestine(1)|lung(8)|prostate(1)|skin(4)	16						CCAATGGCGAAGATTGAGAAA	0.358000													13	63					0	0	1	0	0
SWI5	375757	broad.mit.edu	37	9	131038453	131038453	+	Nonsense_Mutation	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr9:131038453G>A	uc004bup.3	+	0	29	c.29G>A	c.(28-30)tGg>tAg	p.W10*	GOLGA2_uc011maw.2_5'Flank|GOLGA2_uc010mxw.3_5'Flank|GOLGA2_uc004bul.1_5'Flank|SWI5_uc010mxx.1_Nonsense_Mutation_p.W10*	NM_001040011	NP_001035100	Q1ZZU3	SWI5_HUMAN	Homo sapiens SWI5 recombination repair homolog (yeast) (SWI5), mRNA.	10					double-strand break repair via homologous recombination	Swi5-Sfr1 complex	protein binding	p.W10L(1)									AGGGACCTGTGGCGTCACAAC	0.642000													25	100					0	0	1	0	0
ODZ2	57451	broad.mit.edu	37	5	167655091	167655091	+	Missense_Mutation	SNP	G	G	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr5:167655091G>C	uc010jjd.3	+	24	5449	c.5449G>C	c.(5449-5451)Gaa>Caa	p.E1817Q	ODZ2_uc003lzr.4_Missense_Mutation_p.E1587Q|ODZ2_uc003lzt.4_Missense_Mutation_p.E1190Q|ODZ2_uc010jje.3_Missense_Mutation_p.E1081Q	NM_001122679	NP_001116151			Homo sapiens odz, odd Oz/ten-m homolog 2 (Drosophila) (ODZ2), mRNA.											NS(1)|autonomic_ganglia(1)|breast(5)|central_nervous_system(4)|cervix(2)|endometrium(11)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(29)|lung(45)|ovary(8)|pancreas(1)|prostate(3)|skin(2)|stomach(2)|urinary_tract(2)	122	Renal(175;0.00124)|Lung NSC(126;0.136)|all_lung(126;0.242)	Medulloblastoma(196;0.0241)|all_neural(177;0.026)	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.0444)|OV - Ovarian serous cystadenocarcinoma(192;0.0694)|Epithelial(171;0.124)		CCTAAGAAAGGAACAGATTAA	0.517000													3	21					0	0	1	0	0
LOC650368	650368	broad.mit.edu	37	11	3427765	3427765	+	RNA	SNP	G	G	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr11:3427765G>C	uc010qxs.1	+	8		c.758G>C			LOC650368_uc001lxy.2_Non-coding_Transcript					Homo sapiens asparagine-linked glycosylation 1-like pseudogene (LOC650368), non-coding RNA.																		CACACGTCCTGCAGTGGCCTG	0.602000													4	46					0	0	1	0	0
GCC2	9648	broad.mit.edu	37	2	109086210	109086210	+	Missense_Mutation	SNP	G	G	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr2:109086210G>T	uc002tec.3	+	5	579	c.425G>T	c.(424-426)cGt>cTt	p.R142L	GCC2_uc002ted.3_Missense_Mutation_p.R41L	NM_181453	NP_852118	Q8IWJ2	GCC2_HUMAN	Homo sapiens GRIP and coiled-coil domain containing 2 (GCC2), transcript variant 1, mRNA.	142					Golgi ribbon formation|late endosome to Golgi transport|microtubule anchoring|microtubule organizing center organization|protein localization in Golgi apparatus|protein targeting to lysosome|recycling endosome to Golgi transport|regulation of protein exit from endoplasmic reticulum	membrane|trans-Golgi network	identical protein binding			breast(8)|central_nervous_system(1)|endometrium(2)|kidney(5)|large_intestine(10)|lung(19)|ovary(2)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(2)|urinary_tract(3)	54						ATGGCAGTACGTTCCAAATAC	0.338000													22	52					0	0	1	0	0
ILVBL	10994	broad.mit.edu	37	19	15234004	15234004	+	Missense_Mutation	SNP	C	C	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:15234004C>A	uc002nam.3	-	3	509	c.388G>T	c.(388-390)Gtg>Ttg	p.V130L	ILVBL_uc010dzx.1_Missense_Mutation_p.V130L	NM_006844	NP_006835	A1L0T0	ILVBL_HUMAN	Homo sapiens ilvB (bacterial acetolactate synthase)-like (ILVBL), mRNA.	130						integral to membrane	magnesium ion binding|thiamine pyrophosphate binding|transferase activity			NS(3)|breast(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(5)|ovary(2)|skin(1)	26						ACCGCAGTCACCGTGTTGGTG	0.627000													25	103					0	0	1	0	0
TJAP1	93643	broad.mit.edu	37	6	43473228	43473228	+	Missense_Mutation	SNP	G	G	A	rs142853495		TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr6:43473228G>A	uc003ovd.2	+	10	1685	c.1309G>A	c.(1309-1311)Gat>Aat	p.D437N	TJAP1_uc003ovf.2_Missense_Mutation_p.D427N|TJAP1_uc003ove.2_Missense_Mutation_p.D427N|TJAP1_uc003ovc.2_Missense_Mutation_p.D427N|TJAP1_uc010jyp.2_Missense_Mutation_p.D396N|TJAP1_uc011dvh.1_Missense_Mutation_p.D427N|TJAP1_uc003ovg.2_Missense_Mutation_p.D303N|TJAP1_uc011dvi.1_Missense_Mutation_p.D437N|TJAP1_uc011dvj.2_Missense_Mutation_p.D237N|TJAP1_uc003ovi.2_Missense_Mutation_p.D303N	NM_001146016	NP_001139489	Q5JTD0	TJAP1_HUMAN	Homo sapiens tight junction associated protein 1 (peripheral) (TJAP1), transcript variant 1, mRNA.	437						Golgi apparatus|tight junction	protein binding			cervix(1)|endometrium(4)|kidney(1)|large_intestine(1)|lung(11)|ovary(1)|urinary_tract(2)	21	all_lung(25;0.00536)		Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.0122)|OV - Ovarian serous cystadenocarcinoma(102;0.0804)			CTTTGGACGCGATGCCCTCCC	0.622000													18	58					0	0	1	0	0
PBXIP1	57326	broad.mit.edu	37	1	154924328	154924328	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:154924328G>A	uc001ffr.3	-	2	180	c.121C>T	c.(121-123)Cct>Tct	p.P41S	PBXIP1_uc001ffs.3_Missense_Mutation_p.P12S|PBXIP1_uc010pep.2_Intron|PBXIP1_uc009woy.1_Non-coding_Transcript	NM_020524	NP_065385	Q96AQ6	PBIP1_HUMAN	Homo sapiens pre-B-cell leukemia homeobox interacting protein 1 (PBXIP1), mRNA.	41					cell differentiation|multicellular organismal development|negative regulation of transcription, DNA-dependent	cytosol|microtubule|nucleus	protein binding|transcription corepressor activity			breast(1)|kidney(2)|large_intestine(6)|lung(13)|prostate(1)|urinary_tract(1)	24	all_epithelial(22;4.9e-30)|all_lung(78;4.1e-28)|all_hematologic(923;0.0359)|Hepatocellular(266;0.0877)|all_neural(408;0.245)		BRCA - Breast invasive adenocarcinoma(34;0.00034)			GGGCTGTGAGGGGCCTGCAGG	0.582000													39	190					0	0	1	0	0
C10orf140	387640	broad.mit.edu	37	10	21805058	21805058	+	Missense_Mutation	SNP	T	T	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr10:21805058T>A	uc009xkd.3	-	3	3947	c.1694A>T	c.(1693-1695)aAg>aTg	p.K565M	AK055656_uc001iqp.1_Intron|C10orf140_uc021pnx.1_Missense_Mutation_p.K565M	NM_207371	NP_997254	Q1XH10	DLN1_HUMAN	Homo sapiens chromosome 10 open reading frame 140 (C10orf140), mRNA.	484						nucleus	nucleotide binding			kidney(1)|large_intestine(8)|lung(9)|ovary(1)|soft_tissue(1)|urinary_tract(1)	21						GTCAGTTCTCTTTACAGCATT	0.483000													20	65					0	0	1	0	0
FCGBP	8857	broad.mit.edu	37	19	40374061	40374061	+	Missense_Mutation	SNP	T	T	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:40374061T>C	uc002omp.4	-	25	12025	c.12017A>G	c.(12016-12018)aAc>aGc	p.N4006S		NM_003890	NP_003881	Q9Y6R7	FCGBP_HUMAN	Homo sapiens Fc fragment of IgG binding protein (FCGBP), mRNA.	4006	Cys-rich.					extracellular region	protein binding			NS(3)|autonomic_ganglia(1)|breast(7)|central_nervous_system(5)|endometrium(13)|kidney(9)|large_intestine(27)|lung(49)|ovary(8)|pancreas(3)|prostate(13)|skin(9)|stomach(9)|upper_aerodigestive_tract(6)|urinary_tract(3)	165	all_cancers(60;6.03e-06)|all_lung(34;5.58e-08)|Lung NSC(34;6.62e-08)|Ovarian(47;0.06)		Epithelial(26;6.25e-23)|all cancers(26;1.13e-20)			CTGCCGACAGTTGTCAATGAG	0.632000													4	11					0	0	1	0	0
NES	10763	broad.mit.edu	37	1	156641138	156641138	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:156641138C>T	uc001fpq.3	-	3	2975	c.2842G>A	c.(2842-2844)Gtg>Atg	p.V948M	NES_uc021pbh.1_5'Flank	NM_006617	NP_006608	P48681	NEST_HUMAN	Homo sapiens nestin (NES), mRNA.	948	Tail.				G2/M transition of mitotic cell cycle|brain development|embryonic camera-type eye development|negative regulation of apoptosis|positive regulation of intermediate filament depolymerization|positive regulation of neural precursor cell proliferation|stem cell proliferation	cytoplasm|intermediate filament	intermediate filament binding|structural molecule activity			central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(9)|lung(30)|ovary(6)|prostate(1)|skin(3)|stomach(1)|urinary_tract(4)	64	all_hematologic(923;0.088)|Hepatocellular(266;0.158)					CACCTCTGCACATCTGCAGAC	0.552000													5	247					0	0	1	0	0
SPOPL	339745	broad.mit.edu	37	2	139318404	139318404	+	Silent	SNP	T	T	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr2:139318404T>C	uc002tvh.3	+	7	1144	c.744T>C	c.(742-744)ccT>ccC	p.P248P		NM_001001664	NP_001001664	Q6IQ16	SPOPL_HUMAN	Homo sapiens speckle-type POZ protein-like (SPOPL), mRNA.	248	BTB.					nucleus				breast(2)|cervix(2)|endometrium(2)|large_intestine(2)|lung(11)|skin(2)	21				BRCA - Breast invasive adenocarcinoma(221;0.0296)		ATTTAGACCCTGAAGTTTTTA	0.333000													3	52					0	0	1	0	0
HRCT1	646962	broad.mit.edu	37	9	35906559	35906559	+	Missense_Mutation	SNP	A	A	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr9:35906559A>C	uc003zyr.1	+	0	371	c.275A>C	c.(274-276)cAc>cCc	p.H92P	LOC158376_uc003zys.1_5'Flank	NM_001039792	NP_001034881	Q6UXD1	HRCT1_HUMAN	Homo sapiens histidine rich carboxyl terminus 1 (HRCT1), mRNA.	92	His-rich.					integral to membrane		p.H92P(2)		NS(1)|haematopoietic_and_lymphoid_tissue(1)|lung(1)|prostate(1)	4						caccaccaccacccccgccac	0.682000													11	19					0	0	1	0	0
HCN1	348980	broad.mit.edu	37	5	45695922	45695922	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr5:45695922C>T	uc003jok.3	-	0	299	c.274G>A	c.(274-276)Ggc>Agc	p.G92S		NM_021072	NP_066550	O60741	HCN1_HUMAN	Homo sapiens hyperpolarization activated cyclic nucleotide-gated potassium channel 1 (HCN1), mRNA.	92	Involved in subunit assembly (By similarity).					integral to membrane	cAMP binding|sodium channel activity|voltage-gated potassium channel activity	p.Y91*(2)		NS(3)|breast(4)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(21)|liver(1)|lung(98)|ovary(1)|prostate(7)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(5)	156						TGCATGAAGCCGTACTGCCGC	0.697000													7	28					0	0	1	0	0
IL1RAPL2	26280	broad.mit.edu	37	X	104999297	104999297	+	Missense_Mutation	SNP	G	G	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chrX:104999297G>T	uc004elz.1	+	9	2075	c.1319G>T	c.(1318-1320)gGa>gTa	p.G440V		NM_017416	NP_059112	Q9NP60	IRPL2_HUMAN	Homo sapiens interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), mRNA.	440	TIR.				central nervous system development|innate immune response	integral to membrane	interleukin-1, Type II, blocking receptor activity	p.G440*(1)		breast(3)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(14)|lung(23)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	49						AAACACTATGGATATAAACTC	0.368000													33	40					0	0	1	0	0
LRIF1	55791	broad.mit.edu	37	1	111494344	111494344	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:111494344C>T	uc001eaa.3	-	1	1418	c.1162G>A	c.(1162-1164)Gat>Aat	p.D388N	LRIF1_uc001dzz.3_Intron|LRIF1_uc001eab.3_Intron	NM_018372	NP_060842	Q5T3J3	LRIF1_HUMAN	Homo sapiens ligand dependent nuclear receptor interacting factor 1 (LRIF1), transcript variant 1, mRNA.	388					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nuclear matrix	protein binding			endometrium(2)|kidney(2)|large_intestine(7)|lung(12)|ovary(2)|skin(1)|urinary_tract(2)	28						ACTGGAGTATCAGGAGAAACA	0.373000													44	158					0	0	1	0	0
PDPK1	5170	broad.mit.edu	37	16	2636776	2636776	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr16:2636776G>A	uc002cqs.3	+	10	1369	c.1225G>A	c.(1225-1227)Ggc>Agc	p.G409S	PDPK1_uc002cqt.3_Missense_Mutation_p.G282S|PDPK1_uc010bsn.3_Missense_Mutation_p.G409S|PDPK1_uc002cqu.3_Missense_Mutation_p.G382S	NM_002613	NP_002604	O15530	PDPK1_HUMAN	Homo sapiens 3-phosphoinositide dependent protein kinase-1 (PDPK1), transcript variant 1, mRNA.	409					T cell costimulation|T cell receptor signaling pathway|actin cytoskeleton organization|activation of protein kinase B activity|insulin receptor signaling pathway|negative regulation of protein kinase activity|nerve growth factor receptor signaling pathway|peptidyl-threonine phosphorylation|phosphatidylinositol-mediated signaling|platelet activation|positive regulation of establishment of protein localization in plasma membrane|synaptic transmission	cytosol|nucleoplasm|plasma membrane	3-phosphoinositide-dependent protein kinase activity|ATP binding			central_nervous_system(2)|endometrium(1)|large_intestine(1)|lung(2)|ovary(1)	7		Ovarian(90;0.17)			Celecoxib(DB00482)	CCAGAGGTCAGGCAGCAACAT	0.527000													36	111					0	0	1	0	0
KRTAP4-11	653240	broad.mit.edu	37	17	39274424	39274424	+	Missense_Mutation	SNP	G	G	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr17:39274424G>C	uc002hvz.3	-	0	183	c.144C>G	c.(142-144)agC>agG	p.S48R		NM_033059	NP_149048	Q9BYQ6	KR411_HUMAN	Homo sapiens keratin associated protein 4-11 (KRTAP4-11), mRNA.	48	27 X 5 AA repeats of C-C-[GIKRQVHEL]- [SPTR]-[STVQRMC].		Missing (in allele KAP4.14).			keratin filament		p.S48R(4)		endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|lung(8)|prostate(5)|skin(1)	33		Breast(137;0.000496)	STAD - Stomach adenocarcinoma(17;0.000371)			GCCTGCAGCAGCTGGACACAC	0.672000													5	71					0	0	1	0	0
NOL4	8715	broad.mit.edu	37	18	31802972	31802972	+	Nonsense_Mutation	SNP	G	G	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr18:31802972G>T	uc010dmi.3	-	0	544	c.246C>A	c.(244-246)taC>taA	p.Y82*	NOL4_uc002kxr.4_5'Flank|NOL4_uc010xbt.2_5'Flank|NOL4_uc010dmh.3_5'Flank|NOL4_uc010xbu.2_Nonsense_Mutation_p.Y82*|NOL4_uc002kxt.4_Nonsense_Mutation_p.Y82*	NM_003787	NP_001185478	O94818	NOL4_HUMAN	Homo sapiens nucleolar protein 4 (NOL4), transcript variant 1, mRNA.	82						nucleolus	RNA binding			NS(1)|breast(2)|endometrium(6)|kidney(1)|large_intestine(7)|lung(20)|ovary(4)|prostate(2)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(1)	51						TGACAGGCACGTAGAGCACTT	0.627000													9	38					0	0	1	0	0
ZFAT	57623	broad.mit.edu	37	8	135612780	135612780	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr8:135612780T>G	uc003yup.3	-	6	2560	c.2374A>C	c.(2374-2376)Aaa>Caa	p.K792Q	ZFAT_uc003yun.3_Missense_Mutation_p.K780Q|ZFAT_uc003yuo.3_Missense_Mutation_p.K780Q|ZFAT_uc010meh.3_Missense_Mutation_p.K780Q|ZFAT_uc010mej.3_Missense_Mutation_p.K730Q|ZFAT_uc010mei.3_Non-coding_Transcript|ZFAT_uc003yuq.3_Missense_Mutation_p.K780Q|ZFAT_uc003yur.3_Missense_Mutation_p.K780Q|ZFAT-AS1_uc003yus.1_Non-coding_Transcript	NM_020863	NP_001161055	Q9P243	ZFAT_HUMAN	Homo sapiens zinc finger and AT hook domain containing (ZFAT), transcript variant 1, mRNA.	792					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|nucleus	DNA binding|zinc ion binding			autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|endometrium(10)|kidney(9)|large_intestine(8)|lung(16)|prostate(3)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	54	all_epithelial(106;8.26e-19)|Lung NSC(106;3.47e-07)|all_lung(105;1.39e-06)|Ovarian(258;0.0102)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0432)			TTACTGTGTTTCTGAATTACG	0.438000													31	109					0	0	1	0	0
CACNA1I	8911	broad.mit.edu	37	22	40066135	40066135	+	Silent	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr22:40066135C>T	uc003ayc.3	+	24	4287	c.4287C>T	c.(4285-4287)gtC>gtT	p.V1429V	CACNA1I_uc003ayd.3_Silent_p.V1394V|CACNA1I_uc003aye.3_Silent_p.V1344V|CACNA1I_uc003ayf.3_Silent_p.V1309V	NM_021096	NP_066919	Q9P0X4	CAC1I_HUMAN	Homo sapiens calcium channel, voltage-dependent, T type, alpha 1I subunit (CACNA1I), transcript variant 1, mRNA.	1429					axon guidance|signal transduction	voltage-gated calcium channel complex	low voltage-gated calcium channel activity|protein binding			breast(2)|central_nervous_system(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|liver(2)|lung(27)|ovary(1)|pancreas(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	60	Melanoma(58;0.0749)				Flunarizine(DB04841)|Paramethadione(DB00617)|Verapamil(DB00661)	TTGTGGGTGTCGTGGTGGAGA	0.602000													4	265					0	0	1	0	0
TOX3	27324	broad.mit.edu	37	16	52484190	52484190	+	Splice_Site	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr16:52484190C>T	uc002egw.2	-	4	849	c.678_splice	c.e4+1	p.R226_splice	TOX3_uc010vgt.1_Splice_Site_p.R221_splice	NM_001080430	NP_001073899	O15405	TOX3_HUMAN	Homo sapiens TOX high mobility group box family member 3 (TOX3), transcript variant 1, mRNA.	226					apoptosis|negative regulation of neuron apoptosis|positive regulation of anti-apoptosis|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	chromatin binding|estrogen response element binding|phosphoprotein binding|protein homodimerization activity			NS(2)|endometrium(6)|kidney(1)|lung(8)|prostate(3)|stomach(3)|upper_aerodigestive_tract(1)	24						CTAACTTACTCTGTTGGCTTC	0.463000													13	41					0	0	1	0	0
FLG	2312	broad.mit.edu	37	1	152279919	152279919	+	Silent	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:152279919C>T	uc001ezu.1	-	2	7479	c.7443G>A	c.(7441-7443)ttG>ttA	p.L2481L		NM_002016	NP_002007	P20930	FILA_HUMAN	Homo sapiens filaggrin (FLG), mRNA.	2481	Ser-rich.				keratinocyte differentiation	cytoplasmic membrane-bounded vesicle|intermediate filament	calcium ion binding|structural molecule activity			autonomic_ganglia(1)|breast(13)|central_nervous_system(5)|cervix(2)|endometrium(38)|haematopoietic_and_lymphoid_tissue(1)|kidney(16)|large_intestine(57)|lung(211)|ovary(13)|pancreas(1)|prostate(15)|skin(24)|stomach(5)|upper_aerodigestive_tract(10)|urinary_tract(12)	424	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			ATCTATCTACCAATTGCTCGT	0.567000									Ichthyosis				8	523					0	0	1	0	0
BAI3	577	broad.mit.edu	37	6	70064192	70064192	+	Missense_Mutation	SNP	C	C	T	rs142863825		TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr6:70064192C>T	uc010kak.3	+	25	3803	c.3527C>T	c.(3526-3528)tCg>tTg	p.S1176L	BAI3_uc003pev.4_Missense_Mutation_p.S1176L|BAI3_uc011dxx.2_Missense_Mutation_p.S382L	NM_001704	NP_001695	O60242	BAI3_HUMAN	Homo sapiens brain-specific angiogenesis inhibitor 3 (BAI3), mRNA.	1176	Poly-Ser.				negative regulation of angiogenesis|neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(2)|breast(4)|central_nervous_system(5)|endometrium(5)|kidney(2)|large_intestine(28)|liver(1)|lung(111)|ovary(10)|pancreas(4)|prostate(7)|skin(22)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(4)	210		all_lung(197;0.212)				TCTTCGAGTTCGTTTCCTAAT	0.393000													23	77					0	0	1	0	0
FUT2	2524	broad.mit.edu	37	19	49206416	49206416	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:49206416C>T	uc002pke.4	+	1	314	c.203C>T	c.(202-204)gCa>gTa	p.A68V	FUT2_uc010emc.3_Missense_Mutation_p.A68V|FUT2_uc021uwx.1_Missense_Mutation_p.A68V	NM_001097638	NP_001091107	Q10981	FUT2_HUMAN	Homo sapiens fucosyltransferase 2 (secretor status included) (FUT2), transcript variant 2, mRNA.	68					L-fucose catabolic process|protein glycosylation	Golgi cisterna membrane|integral to Golgi membrane	galactoside 2-alpha-L-fucosyltransferase activity			breast(1)|central_nervous_system(2)|endometrium(1)|large_intestine(1)|lung(2)	7		all_lung(116;4.89e-06)|all_epithelial(76;7.04e-06)|Lung NSC(112;9.34e-06)|all_neural(266;0.0189)|Ovarian(192;0.0261)		OV - Ovarian serous cystadenocarcinoma(262;0.00011)|all cancers(93;0.000238)|GBM - Glioblastoma multiforme(486;0.0164)|Epithelial(262;0.017)		ACGATCAATGCAATAGGCCGC	0.607000													9	43					0	0	1	0	0
PCDH15	65217	broad.mit.edu	37	10	55591182	55591182	+	Missense_Mutation	SNP	C	C	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr10:55591182C>A	uc010qhy.1	-	30	4505	c.4110G>T	c.(4108-4110)aaG>aaT	p.K1370N	PCDH15_uc010qhq.2_Missense_Mutation_p.K1370N|PCDH15_uc010qhr.2_Missense_Mutation_p.K1365N|PCDH15_uc021pqv.1_Missense_Mutation_p.K1365N|PCDH15_uc021pqw.1_Missense_Mutation_p.K1377N|PCDH15_uc010qht.2_Missense_Mutation_p.K1372N|PCDH15_uc021pqx.1_Missense_Mutation_p.K1365N|PCDH15_uc001jjv.1_Intron|PCDH15_uc021pqy.1_Missense_Mutation_p.K1365N|PCDH15_uc021pqz.1_Missense_Mutation_p.K1343N|PCDH15_uc010qhv.1_Missense_Mutation_p.K1365N|PCDH15_uc010qhw.1_Missense_Mutation_p.K1328N|PCDH15_uc010qhx.1_Missense_Mutation_p.K1294N|PCDH15_uc010qhz.1_Missense_Mutation_p.K1365N|PCDH15_uc010qia.1_Missense_Mutation_p.K1343N|PCDH15_uc001jju.1_Missense_Mutation_p.K1365N|PCDH15_uc010qib.1_Missense_Mutation_p.K1343N	NM_001142763	NP_001136235	Q96QU1	PCD15_HUMAN	Homo sapiens protocadherin-related 15 (PCDH15), transcript variant A, mRNA.	1365					equilibrioception|homophilic cell adhesion|photoreceptor cell maintenance|sensory perception of sound	extracellular region|extracellular space|integral to membrane|photoreceptor outer segment|plasma membrane|stereocilium|synapse	calcium ion binding			NS(3)|breast(6)|central_nervous_system(1)|cervix(3)|endometrium(18)|haematopoietic_and_lymphoid_tissue(4)|kidney(13)|large_intestine(39)|lung(108)|ovary(5)|pancreas(6)|prostate(6)|skin(12)|upper_aerodigestive_tract(12)|urinary_tract(1)	237		Melanoma(3;0.117)|Lung SC(717;0.238)				TTTCTCCTCTCTTTTTAATGC	0.483000										HNSCC(58;0.16)			12	51					0	0	1	0	0
NUP133	55746	broad.mit.edu	37	1	229577702	229577702	+	Silent	SNP	G	G	A			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr1:229577702G>A	uc001htn.3	-	25	3512	c.3420C>T	c.(3418-3420)ttC>ttT	p.F1140F		NM_018230	NP_060700	Q8WUM0	NU133_HUMAN	Homo sapiens nucleoporin 133kDa (NUP133), mRNA.	1140					carbohydrate metabolic process|glucose transport|mRNA export from nucleus|mitotic prometaphase|nuclear pore organization|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	Nup107-160 complex|condensed chromosome kinetochore|cytosol	nucleocytoplasmic transporter activity|protein binding			NS(1)|breast(7)|endometrium(1)|kidney(6)|large_intestine(9)|lung(20)|ovary(1)|pancreas(1)|prostate(3)|skin(3)|stomach(4)	56	Breast(184;0.104)|Ovarian(103;0.249)	Prostate(94;0.167)				AAACAAACTCGAAGTAAGGAT	0.363000													24	68					0	0	1	0	0
TTC1	7265	broad.mit.edu	37	5	159476556	159476556	+	Silent	SNP	T	T	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr5:159476556T>C	uc003lxu.3	+	5	627	c.577T>C	c.(577-579)Ttg>Ctg	p.L193L		NM_003314	NP_003305	Q99614	TTC1_HUMAN	Homo sapiens tetratricopeptide repeat domain 1 (TTC1), mRNA.	193					protein folding		unfolded protein binding			breast(1)|endometrium(1)|kidney(1)|large_intestine(4)|liver(2)|lung(1)|prostate(1)|skin(1)	12	Renal(175;0.00196)	all_hematologic(541;0.00014)|Breast(839;0.0101)|all_neural(177;0.0281)|Medulloblastoma(196;0.0425)|Lung NSC(249;0.119)|all_lung(500;0.163)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	Epithelial(171;8.37e-05)|all cancers(165;0.000694)|OV - Ovarian serous cystadenocarcinoma(192;0.0402)		CAGGGCAATATTGAGGAGAGC	0.348000													12	30					0	0	1	0	0
RPL37	6167	broad.mit.edu	37	5	40834355	40834355	+	Missense_Mutation	SNP	G	G	C			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr5:40834355G>C	uc003jme.1	-	2	252	c.152C>G	c.(151-153)gCc>gGc	p.A51G	SNORD72_uc003jmf.1_5'Flank	NM_000997	NP_000988	P61927	RL37_HUMAN	Homo sapiens ribosomal protein L37 (RPL37), mRNA.	51					endocrine pancreas development|translational elongation|translational termination|viral transcription	cytosolic large ribosomal subunit	metal ion binding|protein binding|rRNA binding|structural constituent of ribosome			lung(3)|ovary(1)	4		Breast(839;0.238)				TTTAGCCTTGGCACTCCAGTT	0.408000													15	57					0	0	1	0	0
USHBP1	83878	broad.mit.edu	37	19	17370705	17370705	+	Splice_Site	SNP	C	C	T			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:17370705C>T	uc002nfs.1	-	5	881	c.768_splice	c.e5+1	p.Q256_splice	USHBP1_uc002nfr.1_5'Flank|USHBP1_uc002nft.1_Splice_Site|USHBP1_uc010xpk.1_Splice_Site_p.Q192_splice|USHBP1_uc010eam.1_Splice_Site_p.Q184_splice	NM_031941	NP_114147	Q8N6Y0	USBP1_HUMAN	Homo sapiens Usher syndrome 1C binding protein 1 (USHBP1), mRNA.	256							PDZ domain binding			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(4)|large_intestine(10)|liver(1)|lung(12)|ovary(3)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)	44						CTCGCACTCACCTGAGTCTCC	0.542000													11	49					0	0	1	0	0
PPFIA2	8499	broad.mit.edu	37	12	81671195	81671195	+	Splice_Site	DEL	T	T	-			TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr12:81671195delT	uc001szo.2	-	28	3374	c.3213_splice	c.e28-1	p.R1071_splice	PPFIA2_uc010sug.2_Splice_Site|PPFIA2_uc021rbg.1_Splice_Site_p.R970_splice|PPFIA2_uc021rbh.1_Splice_Site_p.R966_splice|PPFIA2_uc021rbi.1_Splice_Site_p.R1065_splice|PPFIA2_uc021rbj.1_Splice_Site_p.R1050_splice|PPFIA2_uc021rbk.1_Splice_Site_p.R1056_splice|PPFIA2_uc021rbl.1_Splice_Site_p.R1071_splice|PPFIA2_uc010sue.2_Intron|PPFIA2_uc021rbe.1_Splice_Site_p.R607_splice|PPFIA2_uc021rbf.1_Splice_Site_p.R257_splice	NM_003625	NP_003616	B7Z663	B7Z663_HUMAN	Homo sapiens protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 (PPFIA2), transcript variant 1, mRNA.	970										NS(1)|autonomic_ganglia(1)|central_nervous_system(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(15)|lung(37)|ovary(3)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(5)	85						AAACTTGTTCtttttttttta	0.333													2	4	---	---	---	---					
PNMAL2	57469	broad.mit.edu	37	19	46997016	46997017	+	In_Frame_Ins	INS	-	-	CGGCCT	rs147338403	by1000genomes	TCGA-G9-6339-01A-12D-A30X-08	TCGA-G9-6339-10A-01D-A30X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6e297e93-6cfe-43b1-aeb2-1151c6fe2a8a	23a6d650-d249-4674-a652-4669df3e3d64	g.chr19:46997016_46997017insCGGCCT	uc002pes.2	-	0	2153_2154	c.1706_1707insAGGCCG	c.(1705-1707)cgg>cgAGGCCGg	p.569_569R>RGR	LOC100506012_uc021uwg.1_Intron|BC132841_uc002peu.1_5'Flank	NM_020709	NP_065760	Q9ULN7	PNML2_HUMAN	Homo sapiens PNMA-like 2 (PNMAL2), mRNA.	571										central_nervous_system(1)|endometrium(2)|large_intestine(1)|lung(4)	8		Ovarian(192;0.00965)|all_neural(266;0.0459)		OV - Ovarian serous cystadenocarcinoma(262;0.000322)|all cancers(93;0.00233)|GBM - Glioblastoma multiforme(486;0.0421)|Epithelial(262;0.0427)		GAGTGACGCCCCGGCCTCGGCC	0.777													2	4	---	---	---	---					
