Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ZFP36L1	677	broad.mit.edu	37	14	69256720	69256720	+	Missense_Mutation	SNP	G	G	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr14:69256720G>C	uc021rve.1	-	2	848	c.754C>G	c.(754-756)Cgt>Ggt	p.R252G	ZFP36L1_uc001xki.2_Missense_Mutation_p.R183G|ZFP36L1_uc001xkh.2_Missense_Mutation_p.R183G	NM_001244701	NP_001231630	Q07352	TISB_HUMAN	Homo sapiens zinc finger protein 36, C3H type-like 1 (ZFP36L1), transcript variant 3, mRNA.	183					regulation of mRNA stability	cytosol|nucleus	DNA binding|mRNA binding|protein binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(4)|kidney(1)|large_intestine(1)|liver(2)|lung(9)|ovary(1)|prostate(2)|urinary_tract(1)	21				all cancers(60;0.00203)|BRCA - Breast invasive adenocarcinoma(234;0.00205)|OV - Ovarian serous cystadenocarcinoma(108;0.0401)		GCCAGGGCACGGCGCTCTTCA	0.672000											OREG0022753	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	20	19					0	0	1	0	0
MYO15A	51168	broad.mit.edu	37	17	18022689	18022689	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr17:18022689G>A	uc021trm.1	+	0	794	c.575G>A	c.(574-576)cGc>cAc	p.R192H	MYO15A_uc021trl.1_Missense_Mutation_p.R192H	NM_016239	NP_057323	Q9UKN7	MYO15_HUMAN	Homo sapiens myosin XVA (MYO15A), mRNA.	192	Myosin head-like.				sensory perception of sound	cytoplasm|myosin complex|stereocilium	ATP binding|actin binding|calmodulin binding|motor activity			breast(5)|central_nervous_system(2)|endometrium(17)|kidney(3)|large_intestine(16)|lung(27)|ovary(3)|pancreas(1)|prostate(6)|skin(13)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	99	all_neural(463;0.228)					AGGTTCCCCCGCAGCCGCAGC	0.711000													3	25					0	0	1	0	0
CCDC61	729440	broad.mit.edu	37	19	46518613	46518613	+	Missense_Mutation	SNP	C	C	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr19:46518613C>A	uc002pdw.3	+	7	944	c.944C>A	c.(943-945)gCg>gAg	p.A315E	CCDC61_uc021uwd.1_Intron	NM_001080402	NP_001073871			Homo sapiens coiled-coil domain containing 61 (CCDC61), mRNA.											endometrium(3)|kidney(3)|large_intestine(1)|lung(5)|ovary(1)	13		all_neural(266;0.113)|Ovarian(192;0.127)		OV - Ovarian serous cystadenocarcinoma(262;0.00221)|GBM - Glioblastoma multiforme(486;0.0233)|Epithelial(262;0.164)		CTCGAGGAGGCGAAGGCATCG	0.741000													6	24					0	0	1	0	0
COL24A1	255631	broad.mit.edu	37	1	86210365	86210365	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:86210365T>G	uc001dlj.3	-	56	4731	c.4656A>C	c.(4654-4656)gaA>gaC	p.E1552D	COL24A1_uc001dli.3_Missense_Mutation_p.E667D|COL24A1_uc010osf.2_Non-coding_Transcript|COL24A1_uc010osd.2_Missense_Mutation_p.E852D|COL24A1_uc001dlk.3_Non-coding_Transcript|COL24A1_uc010ose.2_Non-coding_Transcript	NM_152890	NP_690850	Q17RW2	COOA1_HUMAN	Homo sapiens collagen, type XXIV, alpha 1 (COL24A1), mRNA.	1552	Fibrillar collagen NC1.				cell adhesion	collagen	extracellular matrix structural constituent			NS(3)|central_nervous_system(2)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(9)|liver(1)|lung(56)|ovary(4)|prostate(2)|skin(5)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	101				all cancers(265;0.0627)|Epithelial(280;0.0689)		ATACTTTTTGTTCACAGTTAA	0.373000													13	62					0	0	1	0	0
WDR72	256764	broad.mit.edu	37	15	53992051	53992051	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr15:53992051C>T	uc002acj.2	-	12	1703	c.1661G>A	c.(1660-1662)cGg>cAg	p.R554Q	WDR72_uc010bfi.1_Missense_Mutation_p.R554Q	NM_182758	NP_877435	Q3MJ13	WDR72_HUMAN	Homo sapiens WD repeat domain 72 (WDR72), mRNA.	554								p.R554W(1)		NS(1)|breast(1)|endometrium(4)|kidney(4)|large_intestine(18)|lung(29)|prostate(3)|skin(6)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	71				all cancers(107;0.0511)		AAGGTGCTTCCGGGCATGCAG	0.458000													43	109					0	0	1	0	0
LIG1	3978	broad.mit.edu	37	19	48621022	48621022	+	Missense_Mutation	SNP	C	C	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr19:48621022C>A	uc002pia.1	-	25	2576	c.2456G>T	c.(2455-2457)aGc>aTc	p.S819I	LIG1_uc010xze.1_Missense_Mutation_p.S512I|LIG1_uc002phz.1_Non-coding_Transcript|LIG1_uc002pib.1_Non-coding_Transcript|LIG1_uc010xzf.1_Missense_Mutation_p.S751I|LIG1_uc010xzg.1_Missense_Mutation_p.S788I	NM_000234	NP_000225	P18858	DNLI1_HUMAN	Homo sapiens ligase I, DNA, ATP-dependent (LIG1), mRNA.	819					DNA ligation involved in DNA repair|DNA strand elongation involved in DNA replication|S phase of mitotic cell cycle|anatomical structure morphogenesis|base-excision repair|cell division|double-strand break repair via homologous recombination|nucleotide-excision repair, DNA gap filling|telomere maintenance via recombination|telomere maintenance via semi-conservative replication|transcription-coupled nucleotide-excision repair	nucleoplasm	ATP binding|DNA binding|DNA ligase (ATP) activity|metal ion binding			breast(1)|cervix(1)|endometrium(7)|kidney(1)|large_intestine(9)|lung(22)|prostate(2)|skin(1)	44		all_epithelial(76;3.1e-06)|all_lung(116;4.39e-06)|Lung NSC(112;8.96e-06)|all_neural(266;0.0189)|Ovarian(192;0.0261)|Breast(70;0.203)		OV - Ovarian serous cystadenocarcinoma(262;8.45e-05)|all cancers(93;0.000423)|Epithelial(262;0.0177)|GBM - Glioblastoma multiforme(486;0.0329)	Bleomycin(DB00290)	AGGGCGTGGGCTGGGCAGCAC	0.622000								Nucleotide excision repair (NER)					5	22					0	0	1	0	0
ITIH2	3698	broad.mit.edu	37	10	7751115	7751115	+	Missense_Mutation	SNP	T	T	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr10:7751115T>A	uc001ijs.3	+	3	485	c.323T>A	c.(322-324)gTt>gAt	p.V108D		NM_002216	NP_002207	P19823	ITIH2_HUMAN	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 2 (ITIH2), mRNA.	108	VIT.				hyaluronan metabolic process	extracellular region	serine-type endopeptidase inhibitor activity			NS(2)|breast(1)|endometrium(8)|kidney(1)|large_intestine(17)|lung(25)|ovary(1)|pancreas(1)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	64						GTGTTTGATGTTCAGATCCCC	0.453000													21	55					0	0	1	0	0
IL25	64806	broad.mit.edu	37	14	23844881	23844881	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr14:23844881G>A	uc001wjr.3	+	1	584	c.326G>A	c.(325-327)cGt>cAt	p.R109H	IL25_uc001wjq.3_Missense_Mutation_p.R93H|CMTM5_uc010akn.3_5'Flank|CMTM5_uc001wju.3_5'Flank|CMTM5_uc010ako.3_5'Flank|CMTM5_uc001wjs.3_5'Flank|CMTM5_uc001wjt.3_5'Flank|CMTM5_uc010akm.3_5'Flank	NM_022789	NP_073626	Q9H293	IL25_HUMAN	Homo sapiens interleukin 25 (IL25), transcript variant 1, mRNA.	109					inflammatory response	extracellular space|membrane	cytokine activity|interleukin-17E receptor binding			NS(1)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(2)|ovary(1)	9	all_cancers(95;2e-05)			GBM - Glioblastoma multiforme(265;0.00665)|READ - Rectum adenocarcinoma(4;0.0276)|Colorectal(4;0.0396)		TACCACGCCCGTTGCCTGTGC	0.632000													12	103					0	0	1	0	0
C3orf19	51244	broad.mit.edu	37	3	14712672	14712672	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr3:14712672A>G	uc003byw.3	+	10	1466	c.1375A>G	c.(1375-1377)Atg>Gtg	p.M459V	C3orf19_uc010hej.3_Missense_Mutation_p.M288V	NM_016474	NP_057558	Q6PII3	CC019_HUMAN	Homo sapiens chromosome 3 open reading frame 19 (C3orf19), mRNA.	459										endometrium(1)|kidney(1)|large_intestine(4)|lung(7)|prostate(1)	14						TCTGGATGACATGATTTCCTA	0.483000													33	48					0	0	1	0	0
COL6A3	1293	broad.mit.edu	37	2	238289893	238289893	+	Missense_Mutation	SNP	G	G	A	rs115881121	by1000genomes	TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr2:238289893G>A	uc002vwl.2	-	4	1847	c.1562C>T	c.(1561-1563)tCg>tTg	p.S521L	COL6A3_uc002vwo.2_Missense_Mutation_p.S315L|COL6A3_uc010znj.1_Missense_Mutation_p.S114L|COL6A3_uc002vwq.3_Missense_Mutation_p.S315L|COL6A3_uc002vwr.3_Missense_Mutation_p.S114L|COL6A3_uc010znk.1_Missense_Mutation_p.S521L	NM_004369	NP_004360	P12111	CO6A3_HUMAN	Homo sapiens collagen, type VI, alpha 3 (COL6A3), transcript variant 1, mRNA.	521	Nonhelical region.|VWFA 3.				axon guidance|cell adhesion|muscle organ development	collagen type VI|extracellular space	serine-type endopeptidase inhibitor activity	p.S521L(2)|p.G520G(1)		breast(6)|central_nervous_system(7)|cervix(3)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(13)|large_intestine(64)|lung(62)|ovary(14)|pancreas(2)|prostate(11)|skin(14)|stomach(2)|upper_aerodigestive_tract(6)|urinary_tract(4)	217		Breast(86;0.000301)|Renal(207;0.000966)|all_hematologic(139;0.067)|Ovarian(221;0.0694)|all_lung(227;0.0943)|Melanoma(123;0.203)		Epithelial(121;1.23e-21)|OV - Ovarian serous cystadenocarcinoma(60;1.34e-10)|Kidney(56;5.71e-09)|KIRC - Kidney renal clear cell carcinoma(57;1.51e-07)|BRCA - Breast invasive adenocarcinoma(100;0.00025)|Lung(119;0.0142)|LUSC - Lung squamous cell carcinoma(224;0.034)		GTACAGGGCCGAGCCGTCCAG	0.517000													29	65					0	0	1	0	0
DAB2IP	153090	broad.mit.edu	37	9	124532879	124532879	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr9:124532879G>A	uc004bln.3	+	10	1939	c.1870G>A	c.(1870-1872)Gca>Aca	p.A624T	DAB2IP_uc004blo.3_Missense_Mutation_p.A528T|DAB2IP_uc004blp.3_Missense_Mutation_p.A79T	NM_032552	NP_115941	Q5VWQ8	DAB2P_HUMAN	Homo sapiens DAB2 interacting protein (DAB2IP), transcript variant 1, mRNA.	652					activation of JUN kinase activity|apoptosis in response to endoplasmic reticulum stress|cellular response to epidermal growth factor stimulus|cellular response to tumor necrosis factor|negative regulation of I-kappaB kinase/NF-kappaB cascade|negative regulation of MAP kinase activity|negative regulation of NF-kappaB transcription factor activity|negative regulation of Ras GTPase activity|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of catenin import into nucleus|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of epithelial cell migration|negative regulation of epithelial cell proliferation|negative regulation of epithelial to mesenchymal transition|negative regulation of fibroblast proliferation|negative regulation of transcription from RNA polymerase II promoter|positive regulation of apoptosis|positive regulation of transcription from RNA polymerase II promoter	cytoplasm|intrinsic to internal side of plasma membrane	14-3-3 protein binding|Ras GTPase activator activity|death receptor binding|mitogen-activated protein kinase kinase kinase binding|protein homodimerization activity|protein phosphatase 2A binding|signaling adaptor activity	p.A528>?(1)		breast(3)|central_nervous_system(2)|cervix(1)|endometrium(3)|large_intestine(8)|lung(6)|ovary(1)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)	27						CGTCCACACAGCACTGAGCAC	0.612000													3	40					0	0	1	0	0
ARMC3	219681	broad.mit.edu	37	10	23287302	23287302	+	Silent	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr10:23287302G>A	uc001irm.4	+	10	1484	c.1401G>A	c.(1399-1401)gcG>gcA	p.A467A	ARMC3_uc010qcv.2_Silent_p.A467A|ARMC3_uc010qcw.2_Silent_p.A204A	NM_173081	NP_775104	Q5W041	ARMC3_HUMAN	Homo sapiens armadillo repeat containing 3 (ARMC3), mRNA.	467							binding			breast(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(8)|lung(24)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(2)	47						CCGCAACTGCGTGTGACGTTG	0.458000													13	15					0	0	1	0	0
ANKRD52	283373	broad.mit.edu	37	12	56647135	56647135	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr12:56647135G>A	uc001skm.4	-	9	1127	c.1037C>T	c.(1036-1038)gCt>gTt	p.A346V		NM_173595	NP_775866	Q8NB46	ANR52_HUMAN	Homo sapiens ankyrin repeat domain 52 (ANKRD52), mRNA.	346							protein binding			endometrium(9)|kidney(2)|large_intestine(8)|lung(6)|ovary(2)|prostate(1)|skin(1)	29						ATATCGAGCAGCCACATGCAG	0.582000													59	94					0	0	1	0	0
SUFU	51684	broad.mit.edu	37	10	104309804	104309804	+	Missense_Mutation	SNP	C	C	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr10:104309804C>G	uc001kvy.2	+	2	586	c.395C>G	c.(394-396)gCc>gGc	p.A132G	SUFU_uc001kvw.2_Missense_Mutation_p.A132G|SUFU_uc001kvx.3_Missense_Mutation_p.A132G	NM_016169	NP_057253	Q9UMX1	SUFU_HUMAN	Homo sapiens suppressor of fused homolog (Drosophila) (SUFU), transcript variant 1, mRNA.	132					negative regulation of transcription from RNA polymerase II promoter|proteolysis|skeletal system development	cytoplasm|nucleus	identical protein binding|protein binding|signal transducer activity|transcription corepressor activity|transcription factor binding			breast(2)|central_nervous_system(7)|endometrium(4)|kidney(1)|large_intestine(3)|lung(4)|prostate(1)|skin(2)	24		Colorectal(252;0.207)		Epithelial(162;1.36e-08)|all cancers(201;3.81e-07)|BRCA - Breast invasive adenocarcinoma(275;0.242)		GGGGAGTCTGCCCCACCAACA	0.522000			"""D, F, S"""		medulloblastoma	medulloblastoma			Medulloblastoma, associated with Germline SUFU Mutation				13	36					0	0	1	0	0
ZNF484	83744	broad.mit.edu	37	9	95609134	95609134	+	Silent	SNP	A	A	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr9:95609134A>G	uc004asu.1	-	4	2084	c.1935T>C	c.(1933-1935)ttT>ttC	p.F645F	ANKRD19P_uc004asr.4_Intron|ZNF484_uc011lub.1_Silent_p.F647F|ZNF484_uc004asv.1_Silent_p.F609F|ZNF484_uc010mrb.1_Silent_p.F609F	NM_031486	NP_001007102	Q5JVG2	ZN484_HUMAN	Homo sapiens zinc finger protein 484 (ZNF484), transcript variant 1, mRNA.	645					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(1)|breast(1)|cervix(1)|kidney(8)|large_intestine(10)|lung(10)|prostate(2)	33						ATCTGTCAGTAAAAGCCTTTC	0.423000													4	90					0	0	1	0	0
ZNF658	26149	broad.mit.edu	37	9	40774830	40774830	+	Missense_Mutation	SNP	C	C	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr9:40774830C>A	uc004abs.2	-	4	597	c.445G>T	c.(445-447)Gct>Tct	p.A149S	ZNF658_uc010mmm.2_Missense_Mutation_p.A149S|ZNF658_uc010mmn.1_Missense_Mutation_p.A149S	NM_033160	NP_149350	Q5TYW1	ZN658_HUMAN	Homo sapiens zinc finger protein 658 (ZNF658), mRNA.	149					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(3)|central_nervous_system(1)|endometrium(6)|kidney(1)|large_intestine(9)|lung(21)|ovary(2)|prostate(1)|upper_aerodigestive_tract(2)	46				GBM - Glioblastoma multiforme(29;0.02)|Lung(182;0.0681)		AATTGAGAAGCAACTGGCAAA	0.323000													3	7					0	0	1	0	0
TPP1	1200	broad.mit.edu	37	11	6640071	6640071	+	Silent	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr11:6640071C>T	uc001mel.1	-	2	226	c.165G>A	c.(163-165)caG>caA	p.Q55Q	TPP1_uc001mek.1_5'UTR|TPP1_uc010rar.1_Silent_p.Q55Q	NM_000391	NP_000382	O14773	TPP1_HUMAN	Homo sapiens tripeptidyl peptidase I (TPP1), mRNA.	55					bone resorption|cell death|lipid metabolic process|lysosome organization|nervous system development|neuromuscular process controlling balance|peptide catabolic process|protein catabolic process|proteolysis	lysosome|melanosome|soluble fraction	metal ion binding|peptide binding|protein binding|serine-type endopeptidase activity|tripeptidyl-peptidase activity			breast(2)|central_nervous_system(1)|endometrium(2)|large_intestine(6)|lung(9)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	23		Medulloblastoma(188;0.00263)|all_neural(188;0.026)		Epithelial(150;3.45e-09)|BRCA - Breast invasive adenocarcinoma(625;0.131)		CCACATTCTGCTGTCTCAGGG	0.612000													26	60					0	0	1	0	0
C9orf41	138199	broad.mit.edu	37	9	77599836	77599836	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr9:77599836C>T	uc004ajq.3	-	6	1268	c.1115G>A	c.(1114-1116)gGa>gAa	p.G372E	BC043649_uc004ajp.3_Intron|C9orf41_uc011lsi.1_Non-coding_Transcript	NM_152420	NP_689633	Q8N4J0	CI041_HUMAN	Homo sapiens chromosome 9 open reading frame 41 (C9orf41), mRNA.	372										endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(5)|ovary(1)|skin(1)|urinary_tract(2)	17						TACCTTGAATCCATACTGCAG	0.368000													3	39					0	0	1	0	0
AGMO	392636	broad.mit.edu	37	7	15430468	15430468	+	Missense_Mutation	SNP	A	A	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr7:15430468A>G	uc003stb.1	-	6	909	c.739T>C	c.(739-741)Ttt>Ctt	p.F247L		NM_001004320	NP_001004320	Q6ZNB7	ALKMO_HUMAN	Homo sapiens alkylglycerol monooxygenase (AGMO), mRNA.	247					ether lipid metabolic process|fatty acid biosynthetic process|membrane lipid metabolic process	endoplasmic reticulum membrane|integral to membrane	glyceryl-ether monooxygenase activity|iron ion binding			breast(1)|kidney(1)|large_intestine(6)|liver(1)|lung(30)|prostate(1)|skin(2)	42						TACTTACCAAAAATTTTATCC	0.259000													4	13					0	0	1	0	0
PRG4	10216	broad.mit.edu	37	1	186276981	186276981	+	Silent	SNP	A	A	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:186276981A>G	uc001gru.4	+	6	2181	c.2130A>G	c.(2128-2130)aaA>aaG	p.K710K	MIR548F1_uc021pgf.1_Intron|PRG4_uc001grt.4_Silent_p.K669K|PRG4_uc009wyl.3_Silent_p.K617K|PRG4_uc009wym.3_Silent_p.K576K|PRG4_uc010poo.2_Intron	NM_005807	NP_005798	Q92954	PRG4_HUMAN	Homo sapiens proteoglycan 4 (PRG4), transcript variant A, mRNA.	710	59 X 8 AA repeats of K-X-P-X-P-T-T-X.				cell proliferation|immune response	extracellular region	polysaccharide binding|protein binding|scavenger receptor activity			NS(2)|breast(1)|central_nervous_system(1)|endometrium(26)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(12)|lung(33)|prostate(7)|skin(9)|upper_aerodigestive_tract(2)|urinary_tract(1)	102						CTACCCCTAAAGGGACTGCTC	0.582000													4	87					0	0	1	0	0
NETO1	81832	broad.mit.edu	37	18	70423359	70423359	+	Missense_Mutation	SNP	A	A	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr18:70423359A>C	uc002lkw.3	-	7	1176	c.892T>G	c.(892-894)Ttc>Gtc	p.F298V	NETO1_uc002lky.2_Missense_Mutation_p.F298V	NM_001201465	NP_001188394	Q8TDF5	NETO1_HUMAN	Homo sapiens neuropilin (NRP) and tolloid (TLL)-like 1 (NETO1), transcript variant 4, mRNA.	298	LDL-receptor class A.				memory|regulation of long-term neuronal synaptic plasticity|visual learning	cell junction|excitatory synapse|extracellular region|integral to membrane|postsynaptic density|postsynaptic membrane	receptor activity			NS(3)|breast(2)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(7)|lung(36)|ovary(2)|prostate(3)|skin(3)|stomach(1)	63		Esophageal squamous(42;0.129)		READ - Rectum adenocarcinoma(1;0.0487)		CTATGGCAGAAGAATGTGTTG	0.353000													21	34					0	0	1	0	0
TTC26	79989	broad.mit.edu	37	7	138851601	138851601	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr7:138851601C>T	uc003vus.2	+	9	1025	c.911C>T	c.(910-912)gCt>gTt	p.A304V	TTC26_uc003vur.4_Missense_Mutation_p.A304V|TTC26_uc011kqn.1_Missense_Mutation_p.A304V|TTC26_uc011kqo.1_Missense_Mutation_p.A273V|TTC26_uc011kqp.1_Missense_Mutation_p.A199V|TTC26_uc003vut.2_Missense_Mutation_p.A164V|TTC26_uc011kqq.1_Missense_Mutation_p.A173V	NM_024926	NP_079202	A0AVF1	TTC26_HUMAN	Homo sapiens tetratricopeptide repeat domain 26 (TTC26), transcript variant 1, mRNA.	304							binding			breast(1)|endometrium(5)|kidney(2)|large_intestine(3)|lung(7)|ovary(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	24						GTACAAGAAGCTTATAACTTA	0.348000													5	56					0	0	1	0	0
GDAP2	54834	broad.mit.edu	37	1	118426197	118426197	+	Missense_Mutation	SNP	A	A	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:118426197A>C	uc001ehf.3	-	10	1459	c.1160T>G	c.(1159-1161)gTa>gGa	p.V387G	GDAP2_uc001ehg.3_Missense_Mutation_p.V387G	NM_017686	NP_060156	Q9NXN4	GDAP2_HUMAN	Homo sapiens ganglioside induced differentiation associated protein 2 (GDAP2), transcript variant 1, mRNA.	387	CRAL-TRIO.									kidney(2)|large_intestine(3)|lung(9)|ovary(2)	16		all_cancers(81;0.0156)|all_lung(203;5.81e-05)|Lung NSC(69;0.000446)|all_epithelial(167;0.00295)		Lung(183;0.0583)|LUSC - Lung squamous cell carcinoma(189;0.194)		ATACACTAATACATACTCCTT	0.363000													3	40					0	0	1	0	0
PLA2G4A	5321	broad.mit.edu	37	1	186862236	186862236	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:186862236T>G	uc001gsc.3	+	3	414	c.209T>G	c.(208-210)gTg>gGg	p.V70G	PLA2G4A_uc010pos.2_Missense_Mutation_p.V70G	NM_024420	NP_077734	P47712	PA24A_HUMAN	Homo sapiens phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A), mRNA.	70	C2.|Phospholipid binding (Probable).				phospholipid catabolic process|platelet activating factor biosynthetic process|platelet activation	cytosol|endoplasmic reticulum membrane	calcium ion binding|calcium-dependent phospholipid binding|lysophospholipase activity	p.V70E(2)		breast(3)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(3)|large_intestine(9)|lung(22)|ovary(1)|prostate(3)|skin(4)|stomach(1)	53					Flunisolide(DB00180)|Fluocinolone Acetonide(DB00591)|Fluocinonide(DB01047)|Fluorometholone(DB00324)|Flurandrenolide(DB00846)|Fluticasone Propionate(DB00588)|Medrysone(DB00253)|Quinacrine(DB01103)	ATAAACCCTGTGTGGAATGAG	0.378000													19	151					0	0	1	0	0
IVNS1ABP	10625	broad.mit.edu	37	1	185267218	185267218	+	Nonsense_Mutation	SNP	A	A	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:185267218A>C	uc001grl.3	-	14	2501	c.1878T>G	c.(1876-1878)taT>taG	p.Y626*	IVNS1ABP_uc001gri.3_Nonsense_Mutation_p.Y286*|IVNS1ABP_uc001grj.3_Nonsense_Mutation_p.Y286*|IVNS1ABP_uc009wyj.3_Nonsense_Mutation_p.Y408*|IVNS1ABP_uc009wyk.3_Non-coding_Transcript	NM_006469	NP_006460	Q9Y6Y0	NS1BP_HUMAN	Homo sapiens influenza virus NS1A binding protein (IVNS1ABP), mRNA.	626					RNA splicing|interspecies interaction between organisms|response to virus|transcription from RNA polymerase III promoter	cytoplasm|cytoskeleton|spliceosomal complex|transcription factor complex				breast(1)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|lung(11)|ovary(4)|prostate(2)	29						ACTCAAGGTTATAGACTTCCA	0.403000													52	99					0	0	1	0	0
SOX8	30812	broad.mit.edu	37	16	1033810	1033810	+	Missense_Mutation	SNP	T	T	G			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr16:1033810T>G	uc002ckn.3	+	1	620	c.505T>G	c.(505-507)Tac>Gac	p.Y169D	LMF1_uc002ckk.2_5'Flank|LMF1_uc002ckm.1_5'Flank	NM_014587	NP_055402	P57073	SOX8_HUMAN	Homo sapiens SRY (sex determining region Y)-box 8 (SOX8), mRNA.	169					Sertoli cell development|adipose tissue development|enteric nervous system development|fat cell differentiation|in utero embryonic development|metanephric nephron tubule formation|morphogenesis of a branching epithelium|negative regulation of apoptosis|negative regulation of myoblast differentiation|negative regulation of transcription, DNA-dependent|neural crest cell migration|oligodendrocyte differentiation|osteoblast differentiation|peripheral nervous system development|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of gliogenesis|positive regulation of osteoblast proliferation|positive regulation of transcription from RNA polymerase II promoter|regulation of hormone levels|renal vesicle induction|retinal rod cell differentiation|signal transduction|spermatogenesis|ureter morphogenesis	cytoplasm|nucleus				central_nervous_system(1)|kidney(1)|lung(5)|prostate(2)|skin(1)	10		Hepatocellular(780;0.00308)				CCACCCCGACTACAAGTACCA	0.682000													3	40					0	0	1	0	0
HSF5	124535	broad.mit.edu	37	17	56565351	56565351	+	Silent	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr17:56565351G>A	uc002iwi.1	-	0	409	c.285C>T	c.(283-285)ggC>ggT	p.G95G		NM_001080439	NP_001073908	Q4G112	HSF5_HUMAN	Homo sapiens heat shock transcription factor family member 5 (HSF5), mRNA.	95						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(7)|ovary(3)|skin(1)	16	Medulloblastoma(34;0.127)|all_neural(34;0.237)					CCCCCGGCCCGCCCAGCACCA	0.682000													3	44					0	0	1	0	0
LTF	4057	broad.mit.edu	37	3	46490370	46490370	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr3:46490370C>T	uc003cpq.3	-	8	1437	c.1196G>A	c.(1195-1197)tGc>tAc	p.C399Y	LTF_uc003fzr.3_Missense_Mutation_p.C355Y|LTF_uc010hjh.3_Missense_Mutation_p.C399Y|LTF_uc003cpr.3_Missense_Mutation_p.C386Y	NM_002343	NP_001186078	P02788	TRFL_HUMAN	Homo sapiens lactotransferrin (LTF), transcript variant 1, mRNA.	399	Transferrin-like 2.				cellular iron ion homeostasis|defense response to bacterium|humoral immune response|iron ion transport	extracellular region|stored secretory granule	ferric iron binding|heparin binding|protein binding|serine-type endopeptidase activity			NS(1)|breast(3)|central_nervous_system(3)|endometrium(4)|kidney(3)|large_intestine(5)|lung(13)|ovary(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(2)	40				all cancers(1;7.55e-14)|GBM - Glioblastoma multiforme(1;2.1e-09)|Epithelial(1;9.25e-07)|Colorectal(1;3.81e-05)|BRCA - Breast invasive adenocarcinoma(193;0.00129)|COAD - Colon adenocarcinoma(1;0.00308)|KIRC - Kidney renal clear cell carcinoma(197;0.0205)|Kidney(197;0.0242)|OV - Ovarian serous cystadenocarcinoma(275;0.089)	Pefloxacin(DB00487)	CAGGGCGATGCAGTCCTCTGT	0.637000													11	56					0	0	1	0	0
ZNF799	90576	broad.mit.edu	37	19	12501446	12501446	+	Missense_Mutation	SNP	T	T	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr19:12501446T>C	uc010dyt.3	-	3	1970	c.1766A>G	c.(1765-1767)gAa>gGa	p.E589G	ZNF799_uc002mts.4_Intron	NM_001080821	NP_001074290	Q96GE5	ZN799_HUMAN	Homo sapiens zinc finger protein 799 (ZNF799), mRNA.	589					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(3)|kidney(2)|large_intestine(4)|lung(4)|ovary(2)|prostate(2)|skin(2)	19						TTCCTTACATTCATACGGGTT	0.413000													4	53					0	0	1	0	0
FAM86C1	55199	broad.mit.edu	37	8	8093396	8093396	+	RNA	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr8:8093396C>T	uc011kwt.2	+	4		c.533C>T			FAM86C1_uc010lrq.2_Non-coding_Transcript|FAM86C1_uc003wsf.4_Non-coding_Transcript			Q9NVL1	FA86C_HUMAN	Homo sapiens family with sequence similarity 86, member A pseudogene (FLJ10661), transcript variant 1, non-coding RNA.											lung(1)	1						CACAGCACCACGGGTCTGGTC	0.617000													12	25					0	0	1	0	0
PTPRG	5793	broad.mit.edu	37	3	62257083	62257083	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr3:62257083G>A	uc003dlb.3	+	20	3754	c.3035G>A	c.(3034-3036)cGt>cAt	p.R1012H	PTPRG_uc003dlc.3_Missense_Mutation_p.R983H|PTPRG_uc011bfi.2_Missense_Mutation_p.R258H|LOC100506994_uc003dld.4_Intron|LOC100506994_uc010hnp.3_Intron|LOC100506994_uc003dle.4_Intron|LOC100506994_uc010hno.3_Intron	NM_002841	NP_002832	P23470	PTPRG_HUMAN	Homo sapiens protein tyrosine phosphatase, receptor type, G (PTPRG), mRNA.	1012	Tyrosine-protein phosphatase 1.				transmembrane receptor protein tyrosine kinase signaling pathway	integral to plasma membrane	identical protein binding|transmembrane receptor protein tyrosine phosphatase activity			NS(1)|breast(4)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(12)|liver(2)|lung(15)|ovary(7)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	62				BRCA - Breast invasive adenocarcinoma(55;0.000376)|KIRC - Kidney renal clear cell carcinoma(10;0.0499)|Kidney(10;0.065)		CCCAAGGGTCGTCAGAATGAA	0.468000													6	56					0	0	1	0	0
UBR4	23352	broad.mit.edu	37	1	19481549	19481549	+	Silent	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:19481549C>T	uc001bbi.3	-	43	6325	c.6321G>A	c.(6319-6321)gcG>gcA	p.A2107A	UBR4_uc001bbl.1_Silent_p.A44A|UBR4_uc001bbm.1_Silent_p.A1319A	NM_020765	NP_065816	Q5T4S7	UBR4_HUMAN	Homo sapiens ubiquitin protein ligase E3 component n-recognin 4 (UBR4), mRNA.	2107					interspecies interaction between organisms	cytoplasm|cytoskeleton|integral to membrane|nucleus	calmodulin binding|ubiquitin-protein ligase activity|zinc ion binding			breast(7)|central_nervous_system(1)|cervix(2)|endometrium(23)|kidney(25)|large_intestine(25)|liver(2)|lung(47)|ovary(10)|pancreas(2)|prostate(7)|skin(5)|stomach(5)|upper_aerodigestive_tract(4)|urinary_tract(6)	171		Colorectal(325;3.46e-05)|Renal(390;0.000147)|all_lung(284;0.000328)|Lung NSC(340;0.000406)|Breast(348;0.000814)|Ovarian(437;0.00774)|Myeloproliferative disorder(586;0.0256)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00674)|BRCA - Breast invasive adenocarcinoma(304;5.43e-05)|Kidney(64;0.000337)|KIRC - Kidney renal clear cell carcinoma(64;0.00426)|STAD - Stomach adenocarcinoma(196;0.00715)|READ - Rectum adenocarcinoma(331;0.0816)		CACCACCGCCCGCCACCTGGC	0.483000													10	151					0	0	1	0	0
PIK3CG	5294	broad.mit.edu	37	7	106513199	106513199	+	Silent	SNP	T	T	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr7:106513199T>C	uc003vdv.4	+	3	2188	c.2103T>C	c.(2101-2103)agT>agC	p.S701S	PIK3CG_uc003vdu.3_Silent_p.S701S|PIK3CG_uc003vdw.3_Silent_p.S701S	NM_002649	NP_002640	P48736	PK3CG_HUMAN	Homo sapiens phosphoinositide-3-kinase, catalytic, gamma polypeptide (PIK3CG), mRNA.	701					G-protein coupled receptor protein signaling pathway|phosphatidylinositol-mediated signaling|platelet activation	phosphatidylinositol 3-kinase complex	1-phosphatidylinositol-3-kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|protein binding			breast(7)|central_nervous_system(9)|cervix(1)|endometrium(6)|kidney(4)|large_intestine(16)|liver(4)|lung(59)|ovary(4)|pancreas(4)|prostate(3)|skin(6)|stomach(3)|upper_aerodigestive_tract(5)|urinary_tract(1)	132						TCTTGAGAAGTGAGATAGCCC	0.448000													23	36					0	0	1	0	0
TMEM184B	25829	broad.mit.edu	37	22	38641959	38641959	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr22:38641959C>T	uc003avf.1	-	2	564	c.340G>A	c.(340-342)Gtc>Atc	p.V114I	TMEM184B_uc003avh.2_Missense_Mutation_p.V48I|TMEM184B_uc003avg.2_Missense_Mutation_p.V114I|TMEM184B_uc010gxl.2_Non-coding_Transcript	NM_001195071	NP_001182001	Q9Y519	T184B_HUMAN	Homo sapiens transmembrane protein 184B (TMEM184B), transcript variant 2, mRNA.	114						integral to membrane				endometrium(1)|large_intestine(2)|lung(2)|skin(2)|upper_aerodigestive_tract(1)	8	Melanoma(58;0.045)					CAGTCGCGGACGGTGCCGAAG	0.647000													17	22					0	0	1	0	0
MUC5B	727897	broad.mit.edu	37	11	1266624	1266624	+	Missense_Mutation	SNP	G	G	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr11:1266624G>T	uc001lta.3	+	30	8573	c.8514G>T	c.(8512-8514)agG>agT	p.R2838S		NM_002458	NP_002449	Q9HC84	MUC5B_HUMAN	Homo sapiens mucin 5B, oligomeric mucus/gel-forming (MUC5B), mRNA.	2838	7 X Cys-rich subdomain repeats.|Thr-rich.			Missing (in Ref. 6; AAB61398).	cell adhesion	extracellular region	extracellular matrix structural constituent|protein binding			cervix(2)|endometrium(36)|kidney(9)|lung(89)|urinary_tract(1)	137		all_cancers(49;6.97e-08)|all_epithelial(84;3.45e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.229)		BRCA - Breast invasive adenocarcinoma(625;0.00141)|Lung(200;0.0853)|LUSC - Lung squamous cell carcinoma(625;0.1)		CCACCTCCAGGACCACGGCCA	0.692000													21	41					0	0	1	0	0
YEATS2	55689	broad.mit.edu	37	3	183474355	183474355	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr3:183474355G>A	uc003fly.2	+	11	1625	c.1430G>A	c.(1429-1431)cGa>cAa	p.R477Q		NM_018023	NP_060493	Q9ULM3	YETS2_HUMAN	Homo sapiens YEATS domain containing 2 (YEATS2), mRNA.	477					histone H3 acetylation|negative regulation of transcription from RNA polymerase II promoter	Ada2/Gcn5/Ada3 transcription activator complex	TBP-class protein binding	p.P476S(1)		NS(1)|breast(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(9)|lung(24)|ovary(3)|prostate(2)|skin(3)	49	all_cancers(143;6.55e-10)|Ovarian(172;0.0303)		all cancers(12;2.38e-42)|Epithelial(37;1.9e-36)|OV - Ovarian serous cystadenocarcinoma(80;6.48e-22)			CCATTGCCTCGAACCCCGACT	0.433000													13	137					0	0	1	0	0
ZNF563	147837	broad.mit.edu	37	19	12429722	12429722	+	Missense_Mutation	SNP	T	T	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr19:12429722T>C	uc002mtp.3	-	3	1355	c.1117A>G	c.(1117-1119)Acg>Gcg	p.T373A		NM_145276	NP_660319	Q8TA94	ZN563_HUMAN	Homo sapiens zinc finger protein 563 (ZNF563), mRNA.	373					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(4)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	20						TGAGATAACGTTTTCCCACAC	0.413000													6	150					0	0	1	0	0
RERE	473	broad.mit.edu	37	1	8418294	8418294	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:8418294G>A	uc001ape.3	-	20	5111	c.4301C>T	c.(4300-4302)tCc>tTc	p.S1434F	RERE_uc001apf.3_Missense_Mutation_p.S1434F|RERE_uc001apd.3_Missense_Mutation_p.S880F	NM_012102	NP_036234	Q9P2R6	RERE_HUMAN	Homo sapiens arginine-glutamic acid dipeptide (RE) repeats (RERE), transcript variant 1, mRNA.	1434	His-rich.				NLS-bearing substrate import into nucleus|multicellular organismal development	mitochondrion	poly-glutamine tract binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			central_nervous_system(1)|cervix(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(5)|liver(1)|lung(16)|ovary(3)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(2)	49	Ovarian(185;0.0661)	all_epithelial(116;1.17e-21)|all_lung(118;1.4e-06)|Lung NSC(185;3.06e-06)|Renal(390;0.000147)|Breast(348;0.000206)|Colorectal(325;0.00187)|Hepatocellular(190;0.00825)|Ovarian(437;0.0253)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|all cancers(8;9.64e-67)|GBM - Glioblastoma multiforme(8;9.89e-33)|Colorectal(212;1.45e-07)|COAD - Colon adenocarcinoma(227;3.42e-05)|Kidney(185;6e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000533)|KIRC - Kidney renal clear cell carcinoma(229;0.00106)|STAD - Stomach adenocarcinoma(132;0.00118)|READ - Rectum adenocarcinoma(331;0.0419)|Lung(427;0.195)		gtggaggtgggagtgaatgtg	0.642000													15	12					0	0	1	0	0
SCNN1A	6337	broad.mit.edu	37	12	6471351	6471351	+	Silent	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr12:6471351C>T	uc001qnw.3	-	2	1182	c.918G>A	c.(916-918)gcG>gcA	p.A306A	SCNN1A_uc001qnv.3_5'UTR|SCNN1A_uc001qnx.3_Silent_p.A247A|SCNN1A_uc010sfb.2_Silent_p.A270A	NM_001159576	NP_001029	P37088	SCNNA_HUMAN	Homo sapiens sodium channel, nonvoltage-gated 1 alpha (SCNN1A), transcript variant 2, mRNA.	247					excretion|response to stimulus|sensory perception of taste	apical plasma membrane	WW domain binding			central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|liver(2)|lung(6)|prostate(1)|skin(5)|upper_aerodigestive_tract(3)|urinary_tract(1)	27					Amiloride(DB00594)|Triamterene(DB00384)	ACTCCCTCACCGCATCCACCC	0.567000													11	108					0	0	1	0	0
PRSS23	11098	broad.mit.edu	37	11	86519574	86519574	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr11:86519574G>A	uc021qok.1	+	0	889	c.889G>A	c.(889-891)Gtc>Atc	p.V297I	PRSS23_uc001pcc.1_Intron|PRSS23_uc010rts.1_Missense_Mutation_p.V265I|PRSS23_uc001pcb.3_Missense_Mutation_p.V297I	NM_007173	NP_009104	O95084	PRS23_HUMAN	Homo sapiens protease, serine, 23 (PRSS23), mRNA.	297					proteolysis	extracellular region|nucleus	serine-type endopeptidase activity			central_nervous_system(1)|endometrium(1)|large_intestine(3)|lung(9)|pancreas(1)|skin(1)|stomach(1)|urinary_tract(1)	18		Acute lymphoblastic leukemia(157;2.31e-05)|all_hematologic(158;0.00824)				CTTCTGTGACGTCAAAGACGA	0.557000													8	72					0	0	1	0	0
OR51S1	119692	broad.mit.edu	37	11	4869891	4869891	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr11:4869891G>A	uc010qyo.2	-	0	548	c.548C>T	c.(547-549)aCc>aTc	p.T183I		NM_001004758	NP_001004758	Q8NGJ8	O51S1_HUMAN	Homo sapiens olfactory receptor, family 51, subfamily S, member 1 (OR51S1), mRNA.	183					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(3)|lung(15)|ovary(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(1)	33		Medulloblastoma(188;0.0075)|all_neural(188;0.0577)|Breast(177;0.086)		Epithelial(150;5.06e-12)|BRCA - Breast invasive adenocarcinoma(625;0.00438)|LUSC - Lung squamous cell carcinoma(625;0.19)		ATAAGAATGGGTTAGGACCTG	0.542000													5	129					0	0	1	0	0
RTKN2	219790	broad.mit.edu	37	10	63959566	63959566	+	Missense_Mutation	SNP	C	C	T			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr10:63959566C>T	uc001jlw.3	-	10	1338	c.1241G>A	c.(1240-1242)cGg>cAg	p.R414Q	RTKN2_uc009xpf.1_Missense_Mutation_p.R216Q|RTKN2_uc001jlv.3_Missense_Mutation_p.R68Q	NM_145307	NP_660350	Q8IZC4	RTKN2_HUMAN	Homo sapiens rhotekin 2 (RTKN2), mRNA.	414					signal transduction	intracellular				endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(3)|lung(6)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	21	Prostate(12;0.0297)|all_hematologic(501;0.215)					AGGTGGTTTCCGTGGTGACAT	0.378000													21	50					0	0	1	0	0
SYNPO	11346	broad.mit.edu	37	5	150029062	150029062	+	Silent	SNP	A	A	C			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr5:150029062A>C	uc003lsn.3	+	2	2331	c.1957A>C	c.(1957-1959)Agg>Cgg	p.R653R	SYNPO_uc021yfu.1_Silent_p.R653R|SYNPO_uc003lso.4_Silent_p.R409R|SYNPO_uc003lsp.3_Silent_p.R409R|SYNPO_uc021yfv.1_Silent_p.R409R	NM_001166208	NP_001159681	Q8N3V7	SYNPO_HUMAN	Homo sapiens synaptopodin (SYNPO), transcript variant 3, mRNA.	653					positive regulation of actin filament bundle assembly|regulation of stress fiber assembly	actin cytoskeleton|cytoplasm|dendritic spine|perikaryon|postsynaptic density|postsynaptic membrane|tight junction	actin binding|protein binding			NS(1)|cervix(1)|endometrium(3)|large_intestine(6)|lung(4)|prostate(1)|urinary_tract(2)	18		Medulloblastoma(196;0.134)|all_hematologic(541;0.224)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			GCGGCGGCAGAGGGACCAGGG	0.632000													9	18					0	0	1	0	0
NOTCH2	4853	broad.mit.edu	37	1	120611955	120611955	+	Frame_Shift_Del	DEL	G	-	-			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr1:120611955delG	uc001eik.3	-	0	363	c.66delC	c.(64-66)cccfs	p.P22fs	NOTCH2_uc001eil.3_Frame_Shift_Del_p.P22fs|NOTCH2_uc001eim.4_5'UTR	NM_024408	NP_077719	Q04721	NOTC2_HUMAN	Homo sapiens notch 2 (NOTCH2), transcript variant 1, mRNA.	22					Notch receptor processing|Notch signaling pathway|anti-apoptosis|bone remodeling|cell cycle arrest|cell fate determination|cell growth|hemopoiesis|induction of apoptosis|negative regulation of cell proliferation|nervous system development|organ morphogenesis|positive regulation of Ras protein signal transduction|regulation of transcription, DNA-dependent|stem cell maintenance|transcription, DNA-dependent	Golgi lumen|cell surface|cytosol|endoplasmic reticulum lumen|extracellular region|integral to plasma membrane|nucleoplasm	calcium ion binding|ligand-regulated transcription factor activity|protein binding|receptor activity			breast(4)|central_nervous_system(6)|cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(9)|kidney(9)|large_intestine(19)|liver(1)|lung(57)|ovary(4)|pancreas(1)|prostate(7)|skin(24)|stomach(2)|upper_aerodigestive_tract(5)|urinary_tract(1)	158	all_neural(166;0.153)	all_lung(203;1.96e-06)|Lung NSC(69;1.47e-05)|all_epithelial(167;0.000809)		Lung(183;0.0242)|LUSC - Lung squamous cell carcinoma(189;0.133)		CACCATGCGCGGGGGCCGCGC	0.756			"""N, F, Mis"""		"""marginal zone lymphoma, DLBCL"""				Alagille Syndrome				2	4	---	---	---	---					
DHX15	1665	broad.mit.edu	37	4	24544582	24544582	+	Frame_Shift_Del	DEL	G	-	-			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr4:24544582delG	uc003gqx.3	-	6	1484	c.1316delC	c.(1315-1317)cctfs	p.P439fs		NM_001358	NP_001349	O43143	DHX15_HUMAN	Homo sapiens DEAH (Asp-Glu-Ala-His) box polypeptide 15 (DHX15), mRNA.	439	Helicase C-terminal.				mRNA processing	U12-type spliceosomal complex	ATP binding|ATP-dependent helicase activity|RNA helicase activity|nucleic acid binding			breast(4)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(5)|liver(1)|lung(6)|ovary(1)|upper_aerodigestive_tract(1)	30		Breast(46;0.0503)				CGCAAATCCAGGATCAATCAC	0.313													17	107	---	---	---	---					
VARS2	57176	broad.mit.edu	37	6	30882973	30882975	+	In_Frame_Del	DEL	TAG	-	-			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr6:30882973_30882975delTAG	uc011dmz.2	+	2	413_415	c.332_334delTAG	c.(331-336)ttagta>tta	p.V112del	VARS2_uc003nsc.2_In_Frame_Del_p.V82del|VARS2_uc003nsd.3_In_Frame_Del_p.V82del|VARS2_uc011dmx.2_In_Frame_Del_p.V82del|VARS2_uc011dmy.2_5'UTR|VARS2_uc011dna.2_In_Frame_Del_p.V82del|VARS2_uc011dnb.2_Non-coding_Transcript|VARS2_uc011dnc.2_Non-coding_Transcript	NM_001167734	NP_001161205	Q5ST30	SYVM_HUMAN	Homo sapiens valyl-tRNA synthetase 2, mitochondrial (putative) (VARS2), transcript variant 1, mRNA.	82					valyl-tRNA aminoacylation	mitochondrion	ATP binding|valine-tRNA ligase activity			central_nervous_system(2)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(9)|lung(15)|ovary(3)|prostate(3)|skin(4)|urinary_tract(1)	46						CCTAAGGAGTTAGTATTGTATGA	0.468													20	79	---	---	---	---					
AARS	16	broad.mit.edu	37	16	70287871	70287871	+	Frame_Shift_Del	DEL	T	-	-			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr16:70287871delT	uc002eyn.1	-	17	2581	c.2471delA	c.(2470-2472)aagfs	p.K824fs	EXOSC6_uc002eym.1_5'Flank|AARS_uc010vlu.1_Frame_Shift_Del_p.K654fs	NM_001605	NP_001596	P49588	SYAC_HUMAN	Homo sapiens alanyl-tRNA synthetase (AARS), mRNA.	824					alanyl-tRNA aminoacylation|tRNA processing	cytosol|soluble fraction	ATP binding|alanine-tRNA ligase activity|metal ion binding|tRNA binding			breast(3)|cervix(2)|endometrium(5)|large_intestine(7)|lung(7)|ovary(1)|pancreas(1)|prostate(1)	27		Ovarian(137;0.0365)		BRCA - Breast invasive adenocarcinoma(221;0.161)	L-Alanine(DB00160)	ATCCATGACCTTCTTTAGGGA	0.552											OREG0023912	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	28	165	---	---	---	---					
PANK2	80025	broad.mit.edu	37	20	3893120	3893120	+	Frame_Shift_Del	DEL	T	-	-			TCGA-G9-7525-01A-31D-2260-08	TCGA-G9-7525-10A-01D-2260-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e92edf41-954e-46d6-b1ec-63e2d070f16f	476829e1-ad0a-4621-9ec5-7e20e881c540	g.chr20:3893120delT	uc002wkc.3	+	3	1257	c.1251delT	c.(1249-1251)actfs	p.T417fs	PANK2_uc002wkb.3_Frame_Shift_Del_p.T126fs|PANK2_uc002wkd.3_Non-coding_Transcript|PANK2_uc002wke.3_Frame_Shift_Del_p.T126fs|PANK2_uc002wkf.3_5'UTR	NM_153638	NP_705902	Q9BZ23	PANK2_HUMAN	Homo sapiens pantothenate kinase 2 (PANK2), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.	417					cell death|coenzyme A biosynthetic process|pantothenate metabolic process	mitochondrial intermembrane space|nucleus	ATP binding|pantothenate kinase activity|protein binding			breast(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(5)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	15						GAGGAGGAACTTTTTTTGGTC	0.343													8	229	---	---	---	---					
