Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut	init_n_lod
SVIL	6840	broad.mit.edu	37	10	29759247	29759247	+	Missense_Mutation	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr10:29759247G>A	uc001iut.1	-	32	6554	c.5801C>T	c.(5800-5802)ACG>ATG	p.T1934M	LOC387647_uc001iup.2_Intron|LOC387647_uc001iuq.1_Intron|SVIL_uc010qdw.1_Missense_Mutation_p.T848M|SVIL_uc001iuu.1_Missense_Mutation_p.T1508M	NM_021738	NP_068506	O95425	SVIL_HUMAN	supervillin isoform 2	1934	Gelsolin-like 4.				cytoskeleton organization|skeletal muscle tissue development	cell junction|costamere|invadopodium|nucleus|podosome	actin filament binding			ovary(5)|upper_aerodigestive_tract(1)	6		Breast(68;0.103)				GACCTCCTTCGTGTGGGCCTG	0.597000													20	124					0	0	0.003330	0	0	
DOCK1	1793	broad.mit.edu	37	10	128851029	128851029	+	Silent	SNP	G	T	T			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr10:128851029G>T	uc001ljt.2	+	22	2287	c.2223G>T	c.(2221-2223)GCG>GCT	p.A741A	DOCK1_uc010qun.1_Silent_p.A762A	NM_001380	NP_001371	Q14185	DOCK1_HUMAN	dedicator of cytokinesis 1	741					apoptosis|axon guidance|blood coagulation|integrin-mediated signaling pathway|phagocytosis, engulfment|small GTPase mediated signal transduction	cytosol|membrane	GTP binding|GTPase activator activity|GTPase binding|guanyl-nucleotide exchange factor activity|SH3 domain binding			central_nervous_system(4)|ovary(2)|lung(1)|breast(1)|kidney(1)	9		all_epithelial(44;2.3e-07)|all_lung(145;0.00466)|Lung NSC(174;0.00685)|Colorectal(57;0.0107)|Renal(717;0.0113)|Breast(234;0.0492)|all_neural(114;0.108)|all_hematologic(284;0.14)		BRCA - Breast invasive adenocarcinoma(275;0.0221)|Colorectal(40;0.115)		CCATGAAAGCGCTAGAATCCA	0.502000													11	47					1.08611e-07	1.52055e-07	0.010729	1	0	
LOC653544	653544	broad.mit.edu	37	10	135491123	135491123	+	Missense_Mutation	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr10:135491123G>A	uc010qvi.1	+	1	845	c.734G>A	c.(733-735)GGC>GAC	p.G245D		NM_001127389	NP_001120861	F5GZ66	F5GZ66_HUMAN	double homeobox, 4-like	245						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0						GCCCACACCGGCGCGTGGGGA	0.786000													3	33					0	0	0.001168	0	0	
CHID1	66005	broad.mit.edu	37	11	902239	902239	+	Missense_Mutation	SNP	C	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr11:902239C>A	uc001lsl.2	-	4	514	c.353G>T	c.(352-354)CGT>CTT	p.R118L	CHID1_uc010qwu.1_Missense_Mutation_p.R148L|CHID1_uc010qwv.1_Missense_Mutation_p.R179L|CHID1_uc001lsn.2_Missense_Mutation_p.R143L|CHID1_uc001lsm.2_Missense_Mutation_p.R118L|CHID1_uc001lso.2_Missense_Mutation_p.R118L|CHID1_uc001lsp.2_Missense_Mutation_p.R118L|CHID1_uc010qww.1_Missense_Mutation_p.R118L	NM_023947	NP_076436	Q9BWS9	CHID1_HUMAN	chitinase domain containing 1 isoform a	118					chitin catabolic process|innate immune response	extracellular region|lysosome	cation binding|chitinase activity				0		all_cancers(49;9.46e-06)|Breast(177;0.00257)|all_epithelial(84;0.0027)|Ovarian(85;0.0228)|Medulloblastoma(188;0.0321)|all_neural(188;0.0762)		all cancers(45;5.48e-25)|Epithelial(43;3.75e-24)|BRCA - Breast invasive adenocarcinoma(625;4.65e-05)|Lung(200;0.0624)|LUSC - Lung squamous cell carcinoma(625;0.0735)		AAACATCTCACGGCCACGTCT	0.557000													11	77					6.42651e-13	9.30736e-13	0.010729	1	0	
FAT3	120114	broad.mit.edu	37	11	92616485	92616485	+	Missense_Mutation	SNP	A	C	C			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr11:92616485A>C	uc001pdj.3	+	23	12880	c.12863A>C	c.(12862-12864)AAC>ACC	p.N4288T	FAT3_uc001pdi.3_Missense_Mutation_p.N728T	NM_001008781	NP_001008781	Q8TDW7	FAT3_HUMAN	FAT tumor suppressor homolog 3	4288	Cytoplasmic (Potential).				homophilic cell adhesion|multicellular organismal development	integral to membrane|plasma membrane	calcium ion binding			ovary(4)|pancreas(1)	5		Acute lymphoblastic leukemia(157;3.01e-05)|all_hematologic(158;0.00858)				GTGGCCCCCAACCTCCCCGCC	0.657000										TCGA Ovarian(4;0.039)			9	45					0	0	0.004289	0	0	
Unknown	0	broad.mit.edu	37	13	24515577	24515577	+	RNA	SNP	C	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr13:24515577C>A	uc001upb.1	-	3		c.3713G>T								Homo sapiens cDNA FLJ45359 fis, clone BRHIP3013588.																		AATAATGGCACAAGCCTCTTC	0.433000													11	130					1.99824e-07	2.70729e-07	0.004990	1	0	
MTUS2	23281	broad.mit.edu	37	13	29600602	29600602	+	Missense_Mutation	SNP	C	G	G			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr13:29600602C>G	uc001usl.3	+	1	1855	c.1797C>G	c.(1795-1797)GAC>GAG	p.D599E		NM_001033602	NP_001028774	Q5JR59	MTUS2_HUMAN	hypothetical protein LOC23281 isoform a	589						cytoplasm|microtubule	microtubule binding|protein homodimerization activity				0						AAGTGCCTGACAAGAACACTT	0.532000													3	61					0	0	0.004672	0	0	
Unknown	0	broad.mit.edu	37	14	19857036	19857036	+	RNA	SNP	A	G	G			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr14:19857036A>G	uc001vvq.1	-	5		c.494T>C								Homo sapiens cDNA FLJ12852 fis, clone NT2RP2003445.																		CTGGATAATAAAGTTCATCTC	0.373000													4	120					0	0	0.009096	0	0	
TTLL5	23093	broad.mit.edu	37	14	76241900	76241900	+	Missense_Mutation	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr14:76241900G>A	uc001xrx.2	+	22	2415	c.2210G>A	c.(2209-2211)CGA>CAA	p.R737Q	TTLL5_uc010ask.1_Missense_Mutation_p.R751Q|TTLL5_uc001xrz.2_Missense_Mutation_p.R312Q|TTLL5_uc001xry.1_RNA	NM_015072	NP_055887	Q6EMB2	TTLL5_HUMAN	tubulin tyrosine ligase-like family, member 5	737					protein modification process|transcription, DNA-dependent	centrosome|cilium|microtubule basal body|nucleus	tubulin-tyrosine ligase activity			ovary(2)|central_nervous_system(1)	3				BRCA - Breast invasive adenocarcinoma(234;0.029)		TTACCCAGTCGACGATTGGCA	0.448000													8	164					0	0	0.003080	0	0	
TLN2	83660	broad.mit.edu	37	15	63084979	63084979	+	Missense_Mutation	SNP	C	T	T	rs140861754	byFrequency	TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr15:63084979C>T	uc002alb.3	+	43	5876	c.5876C>T	c.(5875-5877)ACG>ATG	p.T1959M	TLN2_uc002alc.3_Missense_Mutation_p.T352M	NM_015059	NP_055874	Q9Y4G6	TLN2_HUMAN	talin 2	1959					cell adhesion|cell-cell junction assembly|cytoskeletal anchoring at plasma membrane	actin cytoskeleton|cytoplasm|focal adhesion|ruffle|synapse	actin binding|insulin receptor binding|structural constituent of cytoskeleton			ovary(5)|upper_aerodigestive_tract(2)|lung(2)|breast(2)	11						CGTGCCGTCACGGAAAAGGTA	0.567000													6	31					0	0	0.001984	0	0	
CDH1	999	broad.mit.edu	37	16	68844172	68844172	+	Missense_Mutation	SNP	G	T	T			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr16:68844172G>T	uc002ewg.1	+	6	884	c.760G>T	c.(760-762)GAT>TAT	p.D254Y	CDH1_uc010vlj.1_RNA|CDH1_uc010cfg.1_Missense_Mutation_p.D254Y	NM_004360	NP_004351	P12830	CADH1_HUMAN	cadherin 1, type 1 preproprotein	254	Cadherin 1.|Extracellular (Potential).				adherens junction organization|cellular component disassembly involved in apoptosis|cellular response to indole-3-methanol|cellular response to lithium ion|homophilic cell adhesion|negative regulation of cell-cell adhesion|positive regulation of transcription factor import into nucleus|positive regulation of transcription, DNA-dependent|regulation of immune response	actin cytoskeleton|aggresome|apical junction complex|catenin complex|cell-cell adherens junction|endosome|focal adhesion|Golgi apparatus|integral to membrane|internal side of plasma membrane|lateral plasma membrane|perinuclear region of cytoplasm	cell adhesion molecule binding|gamma-catenin binding	p.?(2)|p.D254fs*9(1)|p.D254H(1)|p.D254Y(1)		breast(148)|stomach(71)|biliary_tract(8)|endometrium(3)|soft_tissue(2)|large_intestine(2)|urinary_tract(2)|oesophagus(2)|ovary(2)|thyroid(1)|central_nervous_system(1)|lung(1)	243		all_neural(199;0.0189)|Ovarian(137;0.0563)		Epithelial(162;8.44e-05)|all cancers(182;0.000404)|OV - Ovarian serous cystadenocarcinoma(108;0.000426)|BRCA - Breast invasive adenocarcinoma(181;0.0261)		CACGGTAACCGATCAGAATGA	0.468000			Mis|N|F|S		lobular breast|gastric	gastric			Hereditary_Diffuse_Gastric_Cancer				56	155					1.87469e-40	2.91619e-40	0.003610	1	0	
TP53	7157	broad.mit.edu	37	17	7578542	7578542	+	Missense_Mutation	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr17:7578542G>A	uc002gim.2	-	5	582	c.388C>T	c.(388-390)CTC>TTC	p.L130F	TP53_uc002gig.1_Missense_Mutation_p.L130F|TP53_uc002gih.2_Missense_Mutation_p.L130F|TP53_uc010cne.1_5'Flank|TP53_uc010cnf.1_5'UTR|TP53_uc010cng.1_5'UTR|TP53_uc002gii.1_5'UTR|TP53_uc010cnh.1_Missense_Mutation_p.L130F|TP53_uc010cni.1_Missense_Mutation_p.L130F|TP53_uc002gij.2_Missense_Mutation_p.L130F|TP53_uc010cnj.1_RNA|TP53_uc002gin.2_Missense_Mutation_p.L37F|TP53_uc002gio.2_5'UTR|TP53_uc010vug.1_Missense_Mutation_p.L91F	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	130	Required for interaction with FBXO42.||Interaction with HIPK1 (By similarity).|Interaction with AXIN1 (By similarity).		L -> H (in sporadic cancers; somatic mutation).|L -> F (in sporadic cancers; somatic mutation).|L -> I (in a sporadic cancer; somatic mutation).|L -> R (in sporadic cancers; somatic mutation).|L -> V (in sporadic cancers; somatic mutation).|L -> P (in sporadic cancers; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.L130V(11)|p.L130F(7)|p.L130R(7)|p.0?(7)|p.Y126_K132delYSPALNK(6)|p.L130L(4)|p.L130H(3)|p.Y126_N131delYSPALN(3)|p.L130fs*19(2)|p.L130fs*41(2)|p.Y126fs*11(1)|p.S127_Q136del10(1)|p.A129_L130insXX(1)|p.A129_N131delALN(1)|p.L130P(1)|p.V73fs*9(1)|p.Y126fs*18(1)|p.L130fs*39(1)|p.L130fs*16(1)|p.A129_K132delALNK(1)|p.L130_M133delLNKM(1)|p.N131fs*27(1)|p.P13fs*18(1)|p.S127fs*36(1)|p.L130del(1)|p.L130fs*40(1)		large_intestine(4656)|breast(2429)|upper_aerodigestive_tract(2212)|lung(2028)|ovary(1592)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1228)|stomach(1136)|urinary_tract(1114)|central_nervous_system(1085)|liver(805)|skin(694)|pancreas(375)|biliary_tract(247)|soft_tissue(209)|prostate(194)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(43)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	22245		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		ATCTTGTTGAGGGCAGGGGAG	0.552000		111	Mis|N|F		breast|colorectal|lung|sarcoma|adrenocortical|glioma|multiple other tumour types	breast|sarcoma|adrenocortical carcinoma|glioma|multiple other tumour types		Other_conserved_DNA_damage_response_genes	Hereditary_Adrenocortical_Cancer|Endometrial_Cancer_Familial_Clustering_of|Hereditary_Breast-Ovarian_Cancer_non-BRCA1/2|Li-Fraumeni_syndrome|Osteosarcoma_Familial_Clustering_of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			6	47					0	0	0.001168	0	0	
SPDYE4	388333	broad.mit.edu	37	17	8656508	8656508	+	Missense_Mutation	SNP	G	T	T			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr17:8656508G>T	uc010cnz.1	-	6	839	c.662C>A	c.(661-663)GCT>GAT	p.A221D		NM_001128076	NP_001121548	A6NLX3	SPDE4_HUMAN	speedy homolog E4	221											0						TGGGTCATAAGCCTGGATCTG	0.617000													5	67					0.00307968	0.00404208	0.003080	1	0	
SPAG5	10615	broad.mit.edu	37	17	26905534	26905534	+	Missense_Mutation	SNP	C	T	T			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr17:26905534C>T	uc002hbq.2	-	21	3303	c.3211G>A	c.(3211-3213)GAG>AAG	p.E1071K	ALDOC_uc002hbp.2_5'Flank|ALDOC_uc010cro.2_5'Flank	NM_006461	NP_006452	Q96R06	SPAG5_HUMAN	sperm associated antigen 5	1071	Potential.				cell division|mitosis|phosphatidylinositol-mediated signaling|spindle organization	condensed chromosome kinetochore|cytoplasm|spindle pole	protein binding			central_nervous_system(1)	1	Lung NSC(42;0.00431)					TGGGTCACCTCCTCTCTAAGG	0.532000													20	116					0	0	0.002299	0	0	
ANKRD36	375248	broad.mit.edu	37	2	97911228	97911228	+	Missense_Mutation	SNP	A	G	G			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr2:97911228A>G	uc010yva.1	+	71	5148	c.4904A>G	c.(4903-4905)AAT>AGT	p.N1635S	ANKRD36_uc002sxr.1_Missense_Mutation_p.N459S|ANKRD36_uc002sxt.1_RNA	NM_001164315	NP_001157787	A6QL64	AN36A_HUMAN	ankyrin repeat domain 36	1635	Potential.										0						TGTAGACTGAATGCTGCTCGA	0.428000													10	146					0	0	0.008291	0	0	
PSD4	23550	broad.mit.edu	37	2	113955401	113955401	+	Silent	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr2:113955401G>A	uc002tjc.2	+	14	2718	c.2535G>A	c.(2533-2535)TCG>TCA	p.S845S	PSD4_uc002tjd.2_Silent_p.S465S|PSD4_uc002tje.2_Silent_p.S815S|PSD4_uc002tjf.2_Silent_p.S466S|PSD4_uc002tjg.2_Silent_p.S11S|PSD4_uc010yxs.1_Silent_p.S75S|PSD4_uc002tjh.2_5'Flank	NM_012455	NP_036587	Q8NDX1	PSD4_HUMAN	pleckstrin and Sec7 domain containing 4	845	PH.				regulation of ARF protein signal transduction	cytoplasm|plasma membrane	ARF guanyl-nucleotide exchange factor activity			ovary(2)	2						TGCACCACTCGCTGGCCACCC	0.647000													11	60					0	0	0.008291	0	0	
GPR155	151556	broad.mit.edu	37	2	175304637	175304637	+	Silent	SNP	G	C	C			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr2:175304637G>C	uc002uit.2	-	16	2692	c.2301C>G	c.(2299-2301)GTC>GTG	p.V767V	GPR155_uc002uiu.2_Silent_p.V767V|GPR155_uc002uiv.2_Silent_p.V767V|GPR155_uc010fqs.2_Silent_p.V739V	NM_001033045	NP_001028217	Q7Z3F1	GP155_HUMAN	G protein-coupled receptor 155 isoform 9	767	DEP.				intracellular signal transduction|transmembrane transport	integral to membrane				ovary(1)	1						TTCTTTCTTTGACAATGTTTC	0.348000													4	53					0	0	0.001984	0	0	
CTSA	5476	broad.mit.edu	37	20	44521890	44521890	+	Missense_Mutation	SNP	A	G	G			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr20:44521890A>G	uc002xqj.3	+	7	1106	c.632A>G	c.(631-633)TAT>TGT	p.Y211C	NEURL2_uc002xqg.1_5'Flank|CTSA_uc002xqh.2_Missense_Mutation_p.Y229C|CTSA_uc002xqi.2_RNA|CTSA_uc010zxi.1_Missense_Mutation_p.Y212C|CTSA_uc002xqk.3_Missense_Mutation_p.Y211C	NM_001127695	NP_001121167	P10619	PPGB_HUMAN	cathepsin A isoform b precursor	211					intracellular protein transport|proteolysis	endoplasmic reticulum|lysosome|nucleus	enzyme activator activity|protein binding|serine-type carboxypeptidase activity			ovary(1)	1		Myeloproliferative disorder(115;0.0122)				CTCTCCTCCTATGAGCAGAAT	0.567000													3	113					0	0	0.004672	0	0	
NRIP1	8204	broad.mit.edu	37	21	16339654	16339654	+	Missense_Mutation	SNP	G	A	A	rs150993445		TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr21:16339654G>A	uc002yjx.2	-	4	1458	c.860C>T	c.(859-861)ACG>ATG	p.T287M		NM_003489	NP_003480	P48552	NRIP1_HUMAN	nuclear receptor interacting protein 1	287	Repression domain 1.				androgen receptor signaling pathway|negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent		androgen receptor binding|estrogen receptor binding|glucocorticoid receptor binding|transcription coactivator activity|transcription corepressor activity				0				Epithelial(23;1.19e-05)|all cancers(11;4.64e-05)|COAD - Colon adenocarcinoma(22;0.000232)|Colorectal(24;0.0006)|OV - Ovarian serous cystadenocarcinoma(11;0.00418)|Lung(58;0.199)|LUSC - Lung squamous cell carcinoma(23;0.24)		TGCATTTTGCGTTTTTAAAGC	0.458000													12	68					0	0	0.001368	0	0	
LOC96610	96610	broad.mit.edu	37	22	22664743	22664743	+	RNA	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr22:22664743G>A	uc011aim.1	+	31		c.2258G>A			LOC96610_uc011aiq.1_RNA					Parts of antibodies, mostly variable regions.												0						CAGACTAAAGGCAAACAAGGA	0.498000													3	33					0	0	0.004672	0	0	
GGT1	2678	broad.mit.edu	37	22	25011062	25011062	+	Missense_Mutation	SNP	C	G	G	rs138472970	by1000genomes	TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr22:25011062C>G	uc003aan.1	+	7	837	c.350C>G	c.(349-351)ACC>AGC	p.T117S	GGT1_uc003aas.1_Missense_Mutation_p.T117S|GGT1_uc003aat.1_Missense_Mutation_p.T117S|GGT1_uc003aau.1_Missense_Mutation_p.T117S|GGT1_uc003aav.1_Missense_Mutation_p.T117S|GGT1_uc003aaw.1_Missense_Mutation_p.T117S|GGT1_uc003aax.1_Missense_Mutation_p.T117S	NM_013430	NP_038347	P19440	GGT1_HUMAN	gamma-glutamyltransferase 1 precursor	117	Extracellular (Potential).				glutathione biosynthetic process	integral to membrane	acyltransferase activity|gamma-glutamyltransferase activity|protein binding				0					Glutathione(DB00143)	GCCTTTGCCACCATGTTCAAC	0.637000													4	81					0	0	0.009096	0	0	
C22orf33	339669	broad.mit.edu	37	22	37395899	37395899	+	Missense_Mutation	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr22:37395899G>A	uc003aqf.2	-	4	762	c.616C>T	c.(616-618)CGG>TGG	p.R206W	C22orf33_uc003aqe.2_Missense_Mutation_p.R121W	NM_001163857	NP_001157329	O43247	EAN57_HUMAN	hypothetical protein LOC339669 isoform 1	206											0						AAGTTTGACCGCATGTTGTAG	0.567000													4	122					0	0	0.009096	0	0	
ZNF860	344787	broad.mit.edu	37	3	32032150	32032150	+	Missense_Mutation	SNP	C	T	T			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr3:32032150C>T	uc011axg.1	+	2	2128	c.1579C>T	c.(1579-1581)CGT>TGT	p.R527C		NM_001137674	NP_001131146	A6NHJ4	ZN860_HUMAN	zinc finger protein 860	527	C2H2-type 11.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)	1						AACCCTTGCACGTCATCATAG	0.378000													10	79					0	0	0.008291	0	0	
PCDHGA8	9708	broad.mit.edu	37	5	140773225	140773225	+	Missense_Mutation	SNP	G	A	A	rs141295392	by1000genomes	TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr5:140773225G>A	uc003lkd.1	+	1	1743	c.845G>A	c.(844-846)CGG>CAG	p.R282Q	PCDHGA1_uc003lji.1_Intron|PCDHGA2_uc003ljk.1_Intron|PCDHGA3_uc003ljm.1_Intron|PCDHGA3_uc010jfx.1_Intron|PCDHGB1_uc003ljo.1_Intron|PCDHGA4_uc003ljq.1_Intron|PCDHGB2_uc003ljs.1_Intron|PCDHGA5_uc003lju.1_Intron|PCDHGB3_uc003ljw.1_Intron|PCDHGA6_uc003ljy.1_Intron|PCDHGA7_uc003lka.1_Intron|PCDHGB4_uc003lkc.1_Intron|PCDHGA8_uc003lkb.3_Missense_Mutation_p.R282Q	NM_032088	NP_114477	Q9Y5G5	PCDG8_HUMAN	protocadherin gamma subfamily A, 8 isoform 1	282	Cadherin 3.|Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			TACAAATTCCGGAAAATTAAT	0.408000													18	118					0	0	0.004990	0	0	
FAT2	2196	broad.mit.edu	37	5	150924600	150924600	+	Missense_Mutation	SNP	G	A	A			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr5:150924600G>A	uc003lue.3	-	9	6101	c.6088C>T	c.(6088-6090)CGG>TGG	p.R2030W	GM2A_uc011dcs.1_Intron	NM_001447	NP_001438	Q9NYQ8	FAT2_HUMAN	FAT tumor suppressor 2 precursor	2030	Extracellular (Potential).|Cadherin 17.				epithelial cell migration|homophilic cell adhesion	cell-cell adherens junction|integral to membrane|nucleus	calcium ion binding			ovary(4)|upper_aerodigestive_tract(1)|skin(1)	6		Medulloblastoma(196;0.0912)|all_hematologic(541;0.104)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			TGCTGCTCCCGGTCAAACGCC	0.507000													4	153					0	0	0.009096	0	0	
AK3	50808	broad.mit.edu	37	9	4713048	4713048	+	Missense_Mutation	SNP	A	C	C			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr9:4713048A>C	uc003ziq.1	-	5	752	c.612T>G	c.(610-612)ATT>ATG	p.I204M	AK3_uc003zip.1_RNA|AK3_uc011lma.1_Missense_Mutation_p.I164M|AK3_uc003zir.1_Missense_Mutation_p.I134M	NM_016282	NP_057366	Q9UIJ7	KAD3_HUMAN	adenylate kinase 3	204					blood coagulation	mitochondrial matrix	ATP binding|GTP binding|nucleoside triphosphate adenylate kinase activity			ovary(2)	2	all_hematologic(13;0.137)	Breast(48;0.238)		GBM - Glioblastoma multiforme(50;0.0302)		CATAGGGCCAAATCTTGTTGG	0.378000													14	80					0	0	0.001855	0	0	
LOC442421	442421	broad.mit.edu	37	9	66500794	66500794	+	RNA	SNP	T	C	C	rs7866420	by1000genomes	TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr9:66500794T>C	uc004aed.1	+	3		c.887T>C								Homo sapiens similar to prostaglandin E receptor 4, subtype EP4; PGE receptor, EP4 subtype; prostaglandin E2 receptor, mRNA (cDNA clone IMAGE:5288780).												0						TTAAAGACTTTGGACCACCTA	0.647000													7	31					0	0	0.001984	0	0	
LOC442421	442421	broad.mit.edu	37	9	66500841	66500841	+	RNA	SNP	C	T	T			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr9:66500841C>T	uc004aed.1	+	3		c.934C>T								Homo sapiens similar to prostaglandin E receptor 4, subtype EP4; PGE receptor, EP4 subtype; prostaglandin E2 receptor, mRNA (cDNA clone IMAGE:5288780).												0						CCACCTGGTGCCCAGGGCTCC	0.632000													4	52					0	0	0.000602	0	0	
MAGEB1	4112	broad.mit.edu	37	X	30269600	30269600	+	Silent	SNP	G	T	T			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chrX:30269600G>T	uc004dcc.2	+	4	1310	c.990G>T	c.(988-990)ACG>ACT	p.T330T	MAGEB1_uc004dcd.2_Silent_p.T330T|MAGEB1_uc004dce.2_Silent_p.T330T	NM_002363	NP_002354	P43366	MAGB1_HUMAN	melanoma antigen family B, 1	330											0						CTACTGCCACGACTTTTAGAG	0.527000													16	111					2.48551e-13	3.72826e-13	0.004990	1	0	
SIRT6	51548	broad.mit.edu	37	19	4174643	4174643	+	Frame_Shift_Del	DEL	T	-	-			TCGA-BR-6803-01A-11D-1882-08	TCGA-BR-6803-11A-01D-1882-08									Somatic	Phase_I	Capture				Illumina GAIIx	2275270e-2d72-4999-9b99-b5c2269ac152	d0480e71-0454-44a5-936e-632da9b69470	g.chr19:4174643delT	uc002lzo.2	-	8	1099	c.1039delA	c.(1039-1041)AGGfs	p.R347fs	SIRT6_uc002lzn.2_3'UTR|SIRT6_uc002lzp.2_3'UTR|SIRT6_uc010xid.1_Frame_Shift_Del_p.R275fs|SIRT6_uc002lzq.2_Frame_Shift_Del_p.R320fs|SIRT6_uc002lzr.2_Frame_Shift_Del_p.R248fs	NM_016539	NP_057623	Q8N6T7	SIRT6_HUMAN	sirtuin 6	347					chromatin silencing|protein ADP-ribosylation	nuclear telomeric heterochromatin|nucleoplasm	NAD(P)+-protein-arginine ADP-ribosyltransferase activity|NAD+ ADP-ribosyltransferase activity|NAD+ binding|NAD-dependent histone deacetylase activity (H3-K9 specific)|protein binding|zinc ion binding			skin(1)	1		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.023)|STAD - Stomach adenocarcinoma(1328;0.18)		GCCTTCACCCTTTTGGGGGGT	0.647													2	4	---	---	---	---						.
