Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut	init_n_lod
PTPN14	5784	broad.mit.edu	37	1	214557344	214557344	+	Silent	SNP	A	G	G			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr1:214557344A>G	uc001hkk.1	-	13	2125	c.1854T>C	c.(1852-1854)CAT>CAC	p.H618H	PTPN14_uc010pty.1_Silent_p.H519H	NM_005401	NP_005392	Q15678	PTN14_HUMAN	protein tyrosine phosphatase, non-receptor type	618					lymphangiogenesis	cytoplasm|cytoskeleton	protein tyrosine phosphatase activity|receptor tyrosine kinase binding			breast(2)|ovary(1)|kidney(1)|skin(1)	5				OV - Ovarian serous cystadenocarcinoma(81;0.00181)|all cancers(67;0.00194)|Epithelial(68;0.0157)|GBM - Glioblastoma multiforme(131;0.155)		GGAGAGACTGATGAACCACCG	0.632000													4	44					0	0	1	0	0	
LOC642826	642826	broad.mit.edu	37	10	47207813	47207813	+	RNA	SNP	T	C	C			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr10:47207813T>C	uc001jei.2	-	12		c.1586A>G			uc009xnf.2_Missense_Mutation_p.H132R					Homo sapiens cDNA, FLJ99065.												0						TTTACTTACATGGTTTGTACA	0.294000													7	23					0	0	1	0	0	
Unknown	0	broad.mit.edu	37	10	48968566	48968566	+	RNA	SNP	A	G	G			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr10:48968566A>G	uc001jgc.1	+	3		c.1234A>G								full-length cDNA clone CS0DI009YC01 of Placenta Cot 25-normalized of Homo sapiens (human).																		ACAGGATAACAAACTGGAAAA	0.284000													4	29					0	0	1	0	0	
NECAP1	25977	broad.mit.edu	37	12	8245589	8245589	+	Missense_Mutation	SNP	C	T	T			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr12:8245589C>T	uc001qtx.2	+	6	692	c.614C>T	c.(613-615)GCC>GTC	p.A205V	NECAP1_uc001qty.2_Missense_Mutation_p.A63V	NM_015509	NP_056324	Q8NC96	NECP1_HUMAN	NECAP endocytosis associated 1	205					endocytosis|protein transport	clathrin coated vesicle membrane|plasma membrane				ovary(1)	1				Kidney(36;0.0915)		TCCTCAGTTGCCATCAGCAAT	0.517000													18	168					0	0	1	0	0	
BEST3	144453	broad.mit.edu	37	12	70049306	70049306	+	Missense_Mutation	SNP	T	G	G			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr12:70049306T>G	uc001svg.2	-	10	1615	c.1388A>C	c.(1387-1389)CAC>CCC	p.H463P	BEST3_uc001svd.1_Intron|BEST3_uc001sve.1_Intron|BEST3_uc001svf.2_Missense_Mutation_p.H250P|BEST3_uc010stm.1_Missense_Mutation_p.H357P	NM_032735	NP_116124	Q8N1M1	BEST3_HUMAN	vitelliform macular dystrophy 2-like 3 isoform	463	Cytoplasmic (Potential).					chloride channel complex|plasma membrane	chloride channel activity				0	Breast(13;2.31e-06)|Esophageal squamous(21;0.187)		Lung(24;0.000278)|OV - Ovarian serous cystadenocarcinoma(12;0.0019)|STAD - Stomach adenocarcinoma(21;0.00694)			CATGCTGAAGTGCAGCGTGGG	0.587000													5	74					0	0	1	0	0	
RIMBP2	23504	broad.mit.edu	37	12	130919389	130919389	+	Missense_Mutation	SNP	C	T	T			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr12:130919389C>T	uc001uil.2	-	11	2256	c.2092G>A	c.(2092-2094)GCG>ACG	p.A698T	RIMBP2_uc001uim.2_Missense_Mutation_p.A606T|RIMBP2_uc001uin.1_Missense_Mutation_p.A357T	NM_015347	NP_056162	O15034	RIMB2_HUMAN	RIM-binding protein 2	698						cell junction|synapse				upper_aerodigestive_tract(3)|ovary(3)|large_intestine(2)|central_nervous_system(2)|pancreas(1)	11	all_neural(191;0.101)|Medulloblastoma(191;0.163)	all_epithelial(31;0.213)		OV - Ovarian serous cystadenocarcinoma(86;4.29e-06)|all cancers(50;4.56e-05)|Epithelial(86;5.41e-05)		TACTGCCCCGCGCTGCTTCTC	0.592000													6	71					0	0	1	0	0	
ATP8A2	51761	broad.mit.edu	37	13	26343262	26343262	+	Silent	SNP	C	T	T			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr13:26343262C>T	uc001uqk.2	+	26	2605	c.2463C>T	c.(2461-2463)GAC>GAT	p.D821D	ATP8A2_uc010tdi.1_Silent_p.D781D|ATP8A2_uc010tdj.1_RNA|ATP8A2_uc010aaj.1_Silent_p.D371D	NM_016529	NP_057613	Q9NTI2	AT8A2_HUMAN	ATPase, aminophospholipid transporter-like,	781	Cytoplasmic (Potential).	Magnesium (By similarity).			ATP biosynthetic process|negative regulation of cell proliferation	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			ovary(2)|large_intestine(1)|skin(1)	4		Breast(139;0.0201)|Lung SC(185;0.0225)		all cancers(112;0.043)|OV - Ovarian serous cystadenocarcinoma(117;0.0748)|Epithelial(112;0.079)		CCATCGGAGACGGCGCCAACG	0.557000													5	69					0	0	1	0	0	
Unknown	0	broad.mit.edu	37	16	32070612	32070612	+	RNA	SNP	A	C	C			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr16:32070612A>C	uc002ecv.1	+	1		c.65A>C								Homo sapiens IGH mRNA for immunoglobulin heavy chain VHDJ region, partial cds, clone:TRH1-22.																		GGTCTCCTGCAAGGCTTCTGG	0.552000													6	63					0	0	1	0	0	
FTO	79068	broad.mit.edu	37	16	53860211	53860211	+	Missense_Mutation	SNP	G	C	C			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr16:53860211G>C	uc002ehr.2	+	3	781	c.559G>C	c.(559-561)GGA>CGA	p.G187R	FTO_uc010vha.1_Intron	NM_001080432	NP_001073901	Q9C0B1	FTO_HUMAN	fat mass and obesity associated	187	Fe2OG dioxygenase domain.				DNA dealkylation involved in DNA repair|oxidative single-stranded DNA demethylation|oxidative single-stranded RNA demethylation|RNA repair	nucleus	DNA-N1-methyladenine dioxygenase activity|ferrous iron binding|oxidative DNA demethylase activity|oxidative RNA demethylase activity|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen				0						ATCCTACAACGGACAAGATGA	0.448000													6	96					0	0	1	0	0	
CDH3	1001	broad.mit.edu	37	16	68718494	68718494	+	Missense_Mutation	SNP	T	A	A			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr16:68718494T>A	uc002ewf.2	+	10	2323	c.1191T>A	c.(1189-1191)GAT>GAA	p.D397E	CDH3_uc010vli.1_Missense_Mutation_p.D342E	NM_001793	NP_001784	P22223	CADH3_HUMAN	cadherin 3, type 1 preproprotein	397	Extracellular (Potential).|Cadherin 3.				adherens junction organization|cell junction assembly|homophilic cell adhesion|response to stimulus|visual perception	integral to membrane	calcium ion binding	p.?(1)		ovary(3)|breast(1)|skin(1)	5		Ovarian(137;0.0564)		OV - Ovarian serous cystadenocarcinoma(108;0.000782)|Epithelial(162;0.0054)|all cancers(182;0.0384)		AGGGTTTGGATTTTGAGGCCA	0.517000													21	310					0	0	1	0	0	
ABCA7	10347	broad.mit.edu	37	19	1042792	1042792	+	Silent	SNP	C	T	T			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr19:1042792C>T	uc002lqw.3	+	7	777	c.546C>T	c.(544-546)AGC>AGT	p.S182S	ABCA7_uc010dsb.1_Silent_p.S44S	NM_019112	NP_061985	Q8IZY2	ABCA7_HUMAN	ATP-binding cassette, sub-family A, member 7	182	Extracellular (By similarity).				phagocytosis|transmembrane transport	ATP-binding cassette (ABC) transporter complex|endosome membrane|Golgi membrane|integral to membrane|plasma membrane	ATP binding|ATPase activity|transporter activity			pancreas(7)|ovary(1)|central_nervous_system(1)	9		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;1.04e-05)|all_lung(49;1.53e-05)|Breast(49;9.42e-05)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CCTTGCACAGCTTGTTGGAGG	0.632000													6	78					0	0	1	0	0	
CRX	1406	broad.mit.edu	37	19	48342758	48342758	+	Missense_Mutation	SNP	C	A	A			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr19:48342758C>A	uc002phq.3	+	4	638	c.434C>A	c.(433-435)CCT>CAT	p.P145H		NM_000554	NP_000545	O43186	CRX_HUMAN	cone-rod homeobox protein	145					organ morphogenesis|response to stimulus|visual perception		leucine zipper domain binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(1)|central_nervous_system(1)	2		all_cancers(25;2.76e-09)|all_epithelial(76;7.01e-07)|all_lung(116;2.48e-06)|Lung NSC(112;5.15e-06)|Ovarian(192;0.0139)|all_neural(266;0.0146)|Breast(70;0.133)		OV - Ovarian serous cystadenocarcinoma(262;0.000266)|all cancers(93;0.000788)|Epithelial(262;0.0226)|GBM - Glioblastoma multiforme(486;0.0521)		TACAGTCCCCCTCTGCCCGGC	0.672000													6	82					5.9392e-07	5.9392e-07	1	1	0	
U2AF1	7307	broad.mit.edu	37	21	44524474	44524474	+	Missense_Mutation	SNP	C	T	T			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr21:44524474C>T	uc002zda.1	-	2	167	c.83G>A	c.(82-84)CGT>CAT	p.R28H	U2AF1_uc002zcy.1_5'UTR|U2AF1_uc002zcz.1_5'UTR|U2AF1_uc002zdb.1_Missense_Mutation_p.R28H|U2AF1_uc010gpi.1_Missense_Mutation_p.R28H|U2AF1_uc002zdc.1_Missense_Mutation_p.R28H	NM_001025203	NP_001020374	Q01081	U2AF1_HUMAN	U2 small nuclear RNA auxillary factor 1 isoform	28	C3H1-type 1.				mRNA 3'-end processing|mRNA export from nucleus|termination of RNA polymerase II transcription	Cajal body|catalytic step 2 spliceosome|nuclear speck	nucleotide binding|RNA binding|zinc ion binding				0						GTCTCCATGACGACATGCTCC	0.363000													4	34					0	0	1	0	0	
CNTN6	27255	broad.mit.edu	37	3	1427322	1427322	+	Missense_Mutation	SNP	G	A	A			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr3:1427322G>A	uc003boz.2	+	20	2812	c.2545G>A	c.(2545-2547)GAA>AAA	p.E849K	CNTN6_uc011asj.1_Missense_Mutation_p.E777K|CNTN6_uc003bpa.2_Missense_Mutation_p.E849K	NM_014461	NP_055276	Q9UQ52	CNTN6_HUMAN	contactin 6 precursor	849	Fibronectin type-III 3.				axon guidance|cell adhesion|central nervous system development|Notch signaling pathway	anchored to membrane|plasma membrane				skin(3)|lung(2)|breast(2)|pancreas(1)	8		all_cancers(2;0.000164)|all_epithelial(2;0.107)		Epithelial(13;0.000233)|all cancers(10;0.0013)|OV - Ovarian serous cystadenocarcinoma(96;0.0139)		TGACTCCAAAGAATCCATGAT	0.348000													9	91					0	0	1	0	0	
BAP1	8314	broad.mit.edu	37	3	52440318	52440318	+	Missense_Mutation	SNP	A	G	G			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr3:52440318A>G	uc003ddx.2	-	9	849	c.734T>C	c.(733-735)CTG>CCG	p.L245P	BAP1_uc003ddw.2_5'Flank|BAP1_uc010hmg.2_5'Flank|BAP1_uc010hmh.2_5'Flank	NM_004656	NP_004647	Q92560	BAP1_HUMAN	BRCA1 associated protein-1	245					monoubiquitinated histone H2A deubiquitination|negative regulation of cell proliferation|protein K48-linked deubiquitination|regulation of cell cycle|regulation of cell growth|ubiquitin-dependent protein catabolic process	cytoplasm|nucleolus|PR-DUB complex	chromatin binding|protein binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity			pleura(32)|eye(28)|lung(2)|ovary(2)|breast(1)	65				BRCA - Breast invasive adenocarcinoma(193;1.72e-05)|Kidney(197;0.0018)|KIRC - Kidney renal clear cell carcinoma(197;0.00203)|OV - Ovarian serous cystadenocarcinoma(275;0.0277)		CAGCACATGCAGCCTGGCCTC	0.607000			N|Mis|F|S|O		uveal melanoma|breast|NSCLC								7	41					0	0	1	0	0	
PAK2	5062	broad.mit.edu	37	3	196534697	196534697	+	Silent	SNP	T	C	C			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr3:196534697T>C	uc003fwy.3	+	7	943	c.621T>C	c.(619-621)GGT>GGC	p.G207G		NM_002577	NP_002568	Q13177	PAK2_HUMAN	p21-activated kinase 2	207					axon guidance|cellular component disassembly involved in apoptosis|interspecies interaction between organisms|negative regulation of protein kinase activity|peptidyl-serine phosphorylation|positive regulation of peptidyl-tyrosine phosphorylation|protein autophosphorylation|regulation of apoptosis|regulation of defense response to virus by virus|regulation of growth|T cell costimulation|T cell receptor signaling pathway|viral reproduction	cytosol|nucleus|perinuclear region of cytoplasm|plasma membrane	ATP binding|identical protein binding|protein kinase binding|protein serine/threonine kinase activity|protein tyrosine kinase activator activity			ovary(1)|lung(1)	2	all_cancers(143;1.8e-08)|Ovarian(172;0.0634)|Breast(254;0.135)		Epithelial(36;1.07e-23)|all cancers(36;6.38e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.5e-18)|LUSC - Lung squamous cell carcinoma(58;1.51e-06)|Lung(62;1.95e-06)	GBM - Glioblastoma multiforme(46;0.00405)		CACCAGTTGGTGATTCACATG	0.373000													6	78					0	0	1	0	0	
F11	2160	broad.mit.edu	37	4	187197452	187197452	+	Silent	SNP	C	T	T	rs142846329	byFrequency	TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr4:187197452C>T	uc003iza.1	+	7	996	c.663C>T	c.(661-663)CCC>CCT	p.P221P		NM_000128	NP_000119	P03951	FA11_HUMAN	coagulation factor XI precursor	221	Apple 3.				blood coagulation, intrinsic pathway|plasminogen activation|positive regulation of fibrinolysis	extracellular space|plasma membrane	heparin binding|serine-type endopeptidase activity				0		all_cancers(14;6.2e-52)|all_epithelial(14;1.62e-38)|all_lung(41;1.34e-13)|Lung NSC(41;3.58e-13)|Melanoma(20;1.91e-06)|Hepatocellular(41;0.00886)|Renal(120;0.00988)|Prostate(90;0.00996)|all_hematologic(60;0.014)|Colorectal(36;0.0161)|all_neural(102;0.202)		OV - Ovarian serous cystadenocarcinoma(60;2.13e-11)|BRCA - Breast invasive adenocarcinoma(30;4.59e-06)|GBM - Glioblastoma multiforme(59;0.000149)|STAD - Stomach adenocarcinoma(60;0.000314)|LUSC - Lung squamous cell carcinoma(40;0.00112)|READ - Rectum adenocarcinoma(43;0.176)	Coagulation Factor IX(DB00100)	TCATGGCTCCCGATGCTTTTG	0.478000													6	68					0	0	1	0	0	
SNX18	112574	broad.mit.edu	37	5	53815333	53815333	+	Silent	SNP	C	T	T	rs151150635		TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr5:53815333C>T	uc003jpj.3	+	1	1741	c.1551C>T	c.(1549-1551)CCC>CCT	p.P517P	SNX18_uc011cqg.1_Silent_p.P517P|SNX18_uc003jpi.3_Silent_p.P517P	NM_052870	NP_443102	Q96RF0	SNX18_HUMAN	sorting nexin 18 isoform b	517	BAR.				cell communication|endocytosis|positive regulation of GTPase activity|protein transport	endomembrane system|endosome membrane|extrinsic to internal side of plasma membrane	phosphatidylinositol binding|protein binding				0		Lung NSC(810;3.46e-05)|Breast(144;0.102)				ACCTGGATCCCGTCATGGACC	0.577000													9	85					0	0	1	0	0	
CAP2	10486	broad.mit.edu	37	6	17421835	17421835	+	Missense_Mutation	SNP	C	T	T			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr6:17421835C>T	uc003ncb.2	+	2	292	c.49C>T	c.(49-51)CGC>TGC	p.R17C	CAP2_uc010jpk.1_RNA|CAP2_uc011dja.1_Missense_Mutation_p.R17C|CAP2_uc011djb.1_Missense_Mutation_p.R17C|CAP2_uc011djc.1_Missense_Mutation_p.R17C|CAP2_uc011djd.1_Missense_Mutation_p.R17C	NM_006366	NP_006357	P40123	CAP2_HUMAN	adenylyl cyclase-associated protein 2	17					activation of adenylate cyclase activity|axon guidance|cytoskeleton organization|establishment or maintenance of cell polarity|signal transduction	plasma membrane	actin binding			ovary(1)	1	Breast(50;0.0333)|Ovarian(93;0.0386)	all_hematologic(90;0.0466)	all cancers(50;0.194)|Epithelial(50;0.227)			AGCTGTCAGCCGCCTGGAGTC	0.562000													10	85					0	0	1	0	0	
KHDRBS2	202559	broad.mit.edu	37	6	62407141	62407141	+	Missense_Mutation	SNP	T	C	C			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr6:62407141T>C	uc003peg.2	-	8	1158	c.911A>G	c.(910-912)GAC>GGC	p.D304G		NM_152688	NP_689901	Q5VWX1	KHDR2_HUMAN	KH domain-containing, RNA-binding, signal	304					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	SH3 domain binding			skin(7)|ovary(3)|liver(1)	11				BRCA - Breast invasive adenocarcinoma(397;0.149)		ATGACCGTAGTCATAGTATTC	0.383000													5	52					0	0	1	0	0	
SLCO5A1	81796	broad.mit.edu	37	8	70744581	70744581	+	Missense_Mutation	SNP	C	T	T	rs34148850	byFrequency	TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr8:70744581C>T	uc003xyl.2	-	2	1035	c.328G>A	c.(328-330)GCC>ACC	p.A110T	SLCO5A1_uc010lzb.2_Missense_Mutation_p.A110T|SLCO5A1_uc011lfa.1_RNA|SLCO5A1_uc003xyk.2_Missense_Mutation_p.A110T|SLCO5A1_uc010lzc.2_Missense_Mutation_p.A110T	NM_030958	NP_112220	Q9H2Y9	SO5A1_HUMAN	solute carrier organic anion transporter family,	110	Cytoplasmic (Potential).					integral to membrane|plasma membrane	transporter activity			ovary(3)|upper_aerodigestive_tract(1)	4	Breast(64;0.0654)		Epithelial(68;0.0141)|OV - Ovarian serous cystadenocarcinoma(28;0.0315)|all cancers(69;0.0594)			ATGGCCAAGGCGGAGGACACC	0.617000											OREG0018815	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	5	64					0	0	1	0	0	
ADCY8	114	broad.mit.edu	37	8	131916177	131916177	+	Silent	SNP	A	C	C			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr8:131916177A>C	uc003ytd.3	-	7	2008	c.1752T>G	c.(1750-1752)ACT>ACG	p.T584T	ADCY8_uc010mds.2_Silent_p.T584T	NM_001115	NP_001106	P40145	ADCY8_HUMAN	adenylate cyclase 8	584	Cytoplasmic (Potential).				activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity|activation of protein kinase A activity|cellular response to glucagon stimulus|energy reserve metabolic process|inhibition of adenylate cyclase activity by G-protein signaling pathway|nerve growth factor receptor signaling pathway|synaptic transmission|transmembrane transport|water transport	integral to membrane|membrane fraction|plasma membrane	ATP binding|calcium- and calmodulin-responsive adenylate cyclase activity|metal ion binding			skin(4)|large_intestine(1)|central_nervous_system(1)	6	Esophageal squamous(12;0.00693)|Ovarian(258;0.00707)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.000538)			TAATTAAGTAAGTTTCGATAT	0.483000										HNSCC(32;0.087)			8	126					0	0	1	0	0	
TNC	3371	broad.mit.edu	37	9	117840372	117840372	+	Missense_Mutation	SNP	C	T	T			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr9:117840372C>T	uc004bjj.3	-	7	2886	c.2524G>A	c.(2524-2526)GTG>ATG	p.V842M	TNC_uc010mvf.2_Missense_Mutation_p.V842M	NM_002160	NP_002151	P24821	TENA_HUMAN	tenascin C precursor	842	Fibronectin type-III 3.				cell adhesion|response to wounding|signal transduction	extracellular space	receptor binding|syndecan binding			central_nervous_system(4)|upper_aerodigestive_tract(1)|ovary(1)|skin(1)	7						TCTCCTGGCACGTCTTTGATG	0.547000													5	41					0	0	1	0	0	
MAGEB3	4114	broad.mit.edu	37	X	30254145	30254145	+	Missense_Mutation	SNP	A	G	G			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chrX:30254145A>G	uc004dca.1	+	5	841	c.104A>G	c.(103-105)AAG>AGG	p.K35R		NM_002365	NP_002356	O15480	MAGB3_HUMAN	melanoma antigen family B, 3	35											0						GCAACTAACAAGAAAAAAGTA	0.517000													3	23					0	0	1	0	0	
MMGT1	93380	broad.mit.edu	37	X	135049608	135049608	+	Silent	SNP	A	G	G			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chrX:135049608A>G	uc004ezi.1	-	3	477	c.177T>C	c.(175-177)GGT>GGC	p.G59G	MMGT1_uc011mvw.1_Silent_p.G124G	NM_173470	NP_775741	Q8N4V1	MMGT1_HUMAN	membrane magnesium transporter 1 precursor	59	Helical; (Potential).					early endosome membrane|endoplasmic reticulum membrane|Golgi membrane|integral to membrane	magnesium ion transmembrane transporter activity				0						TATGAACTATACCGTAACAGG	0.323000													8	67					0	0	1	0	0	
FBN3	84467	broad.mit.edu	37	19	8212045	8212045	+	Frame_Shift_Del	DEL	G	-	-			TCGA-BR-8371-01A-11D-2340-08	TCGA-BR-8371-10A-01D-2341-08									Somatic	Phase_I	Capture				Illumina GAIIx	8509693c-ad35-4c24-80de-f84ae07fe87e	be24ceb1-6f72-48d3-8dc9-7649fd72609f	g.chr19:8212045delG	uc002mjf.2	-	2	214	c.193delC	c.(193-195)CATfs	p.H65fs		NM_032447	NP_115823	Q75N90	FBN3_HUMAN	fibrillin 3 precursor	65						proteinaceous extracellular matrix	calcium ion binding|extracellular matrix structural constituent			ovary(6)|skin(3)|pancreas(1)|central_nervous_system(1)	11						CAGTAGGCATGGAACCGGGAG	0.677													2	4	---	---	---	---						.
