Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MEGF6	1953	broad.mit.edu	37	1	3418372	3418372	+	Missense_Mutation	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:3418372C>A	uc001akl.3	-	17	2529	c.2302G>T	c.(2302-2304)Gac>Tac	p.D768Y	MEGF6_uc001akk.3_Missense_Mutation_p.D663Y	NM_001409	NP_001400	O75095	MEGF6_HUMAN	Homo sapiens multiple EGF-like-domains 6 (MEGF6), mRNA.	768	EGF-like 12.					extracellular region	calcium ion binding			cervix(2)|endometrium(3)|large_intestine(3)|lung(8)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	19	all_cancers(77;0.00681)|all_epithelial(69;0.00301)|Ovarian(185;0.0634)|Lung NSC(156;0.0969)|all_lung(157;0.105)	all_epithelial(116;7.41e-22)|all_lung(118;8.3e-09)|Lung NSC(185;3.55e-06)|Breast(487;0.000659)|Renal(390;0.00121)|Hepatocellular(190;0.00308)|Myeloproliferative disorder(586;0.0255)|Lung SC(97;0.0262)|Ovarian(437;0.0308)|Medulloblastoma(700;0.211)		Epithelial(90;3.78e-37)|OV - Ovarian serous cystadenocarcinoma(86;6.86e-22)|GBM - Glioblastoma multiforme(42;1.96e-12)|Colorectal(212;6.15e-05)|COAD - Colon adenocarcinoma(227;0.000241)|Kidney(185;0.000448)|BRCA - Breast invasive adenocarcinoma(365;0.000779)|KIRC - Kidney renal clear cell carcinoma(229;0.00645)|STAD - Stomach adenocarcinoma(132;0.00669)|Lung(427;0.213)		GCCTCACAGTCTTCCCCAGTC	0.711000													12	22					0	0	1	0	0
AK021933	0	broad.mit.edu	37	GL000195.1	31448	31448	+	RNA	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrGL000195.1:31448G>C	uc003woi.3	-	0		c.533C>G								Homo sapiens cDNA FLJ11871 fis, clone HEMBA1007052.																		CCTCCAGTGAGGCGGACTGCC	0.552000													4	13					0	0	1	0	0
KIF2B	84643	broad.mit.edu	37	17	51901710	51901710	+	Missense_Mutation	SNP	T	T	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:51901710T>G	uc002iua.2	+	0	1472	c.1316T>G	c.(1315-1317)aTg>aGg	p.M439R	KIF2B_uc010wna.1_Non-coding_Transcript	NM_032559	NP_115948	Q8N4N8	KIF2B_HUMAN	Homo sapiens kinesin family member 2B (KIF2B), mRNA.	439	Kinesin-motor.				blood coagulation|cell division|microtubule depolymerization|microtubule-based movement|mitotic prometaphase|regulation of chromosome segregation	condensed chromosome kinetochore|cytosol|microtubule|microtubule organizing center|nucleolus|spindle	ATP binding|microtubule motor activity	p.M439I(1)		NS(1)|breast(2)|endometrium(7)|kidney(2)|large_intestine(15)|lung(58)|ovary(5)|prostate(4)|skin(7)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	104						GGACGGATAATGCATGGCAAG	0.507000													10	42					0	0	1	0	0
OR10A6	390093	broad.mit.edu	37	11	7950117	7950117	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr11:7950117G>A	uc010rbh.2	-	0	93	c.93C>T	c.(91-93)ttC>ttT	p.F31F		NM_001004461	NP_001004461	Q8NH74	O10A6_HUMAN	Homo sapiens olfactory receptor, family 10, subfamily A, member 6 (OR10A6), mRNA.	31					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(9)|lung(5)|ovary(1)|prostate(1)|skin(3)|urinary_tract(1)	22				Epithelial(150;1.38e-07)|BRCA - Breast invasive adenocarcinoma(625;0.189)		AAATAACCAGGAAAGCCACAA	0.448000													86	26					0	0	1	0	0
RUNX2	860	broad.mit.edu	37	6	45390466	45390466	+	Silent	SNP	A	A	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr6:45390466A>G	uc011dvx.2	+	2	405	c.195A>G	c.(193-195)caA>caG	p.Q65Q	RUNX2_uc011dvy.2_Silent_p.Q65Q|RUNX2_uc003oxt.3_Silent_p.Q51Q	NM_001024630	NP_001019801	Q13950	RUNX2_HUMAN	Homo sapiens runt-related transcription factor 2 (RUNX2), transcript variant 1, mRNA.	65	Poly-Gln.				negative regulation of transcription, DNA-dependent|osteoblast differentiation|positive regulation of transcription, DNA-dependent	nucleus	ATP binding|DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			breast(2)|endometrium(2)|kidney(1)|large_intestine(5)|liver(1)|lung(18)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	34						agcagcagcaacagcagcagc	0.731000													3	36					0	0	1	0	0
PPFIA2	8499	broad.mit.edu	37	12	81657012	81657012	+	Missense_Mutation	SNP	T	T	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr12:81657012T>A	uc001szo.2	-	30	3871	c.3710A>T	c.(3709-3711)gAt>gTt	p.D1237V	PPFIA2_uc010sug.2_Non-coding_Transcript|PPFIA2_uc021rbg.1_Missense_Mutation_p.D1136V|PPFIA2_uc021rbh.1_Missense_Mutation_p.D1132V|PPFIA2_uc021rbi.1_Missense_Mutation_p.D1231V|PPFIA2_uc021rbj.1_Missense_Mutation_p.D1216V|PPFIA2_uc021rbk.1_Missense_Mutation_p.D1222V|PPFIA2_uc021rbl.1_Missense_Mutation_p.D1237V|PPFIA2_uc010sue.2_Intron|PPFIA2_uc021rbe.1_Missense_Mutation_p.D773V|PPFIA2_uc021rbf.1_Missense_Mutation_p.D423V	NM_003625	NP_003616	B7Z663	B7Z663_HUMAN	Homo sapiens protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 (PPFIA2), transcript variant 1, mRNA.	1137										NS(1)|autonomic_ganglia(1)|central_nervous_system(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(15)|lung(37)|ovary(3)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(5)	85						TACTGTACCATCTGTTGTCAT	0.398000													3	5					0	0	1	0	0
NCKAP1L	3071	broad.mit.edu	37	12	54914489	54914489	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr12:54914489G>A	uc001sgc.4	+	16	1716	c.1637G>A	c.(1636-1638)cGt>cAt	p.R546H	NCKAP1L_uc010sox.2_Missense_Mutation_p.R88H|NCKAP1L_uc010soy.2_Missense_Mutation_p.R496H	NM_005337	NP_005328	P55160	NCKPL_HUMAN	Homo sapiens NCK-associated protein 1-like (NCKAP1L), transcript variant 1, mRNA.	546					B cell homeostasis|B cell receptor signaling pathway|T cell homeostasis|actin polymerization-dependent cell motility|cortical actin cytoskeleton organization|erythrocyte development|maintenance of cell polarity|myeloid cell homeostasis|negative regulation of apoptosis|negative regulation of interleukin-17 production|negative regulation of interleukin-6 production|negative regulation of myosin-light-chain-phosphatase activity|neutrophil chemotaxis|positive regulation of B cell differentiation|positive regulation of B cell proliferation|positive regulation of CD4-positive, alpha-beta T cell differentiation|positive regulation of CD8-positive, alpha-beta T cell differentiation|positive regulation of T cell proliferation|positive regulation of actin filament polymerization|positive regulation of cell adhesion mediated by integrin|positive regulation of erythrocyte differentiation|positive regulation of gamma-delta T cell differentiation|positive regulation of neutrophil chemotaxis|positive regulation of phagocytosis, engulfment|protein complex assembly|response to drug	SCAR complex|cytosol|integral to plasma membrane|membrane fraction	Rac GTPase activator activity|protein complex binding|protein kinase activator activity			NS(3)|breast(2)|central_nervous_system(2)|cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(12)|lung(37)|ovary(3)|prostate(3)|skin(3)|stomach(2)	80						TTTCATCTTCGTATCTTTGAG	0.393000													35	75					0	0	1	0	0
TP53	7157	broad.mit.edu	37	17	7577120	7577120	+	Missense_Mutation	SNP	C	C	T	rs28934576	by1000genomes	TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:7577120C>T	uc002gim.2	-	7	1012	c.818G>A	c.(817-819)cGt>cAt	p.R273H	TP53_uc002gig.1_Intron|TP53_uc002gih.3_Missense_Mutation_p.R273H|TP53_uc010cne.1_5'Flank|TP53_uc010cng.1_Missense_Mutation_p.R141H|TP53_uc010cnf.1_Missense_Mutation_p.R141H|TP53_uc002gii.1_Missense_Mutation_p.R141H|TP53_uc010cni.1_Missense_Mutation_p.R273H|TP53_uc010cnh.1_Missense_Mutation_p.R273H|TP53_uc002gij.2_Missense_Mutation_p.R273H|DL476366_uc021tpf.1_5'Flank|DL476309_uc021tpg.1_5'Flank|DL476358_uc021tph.1_5'Flank	NM_001126112	NP_001119587	P04637	P53_HUMAN	Homo sapiens tumor protein p53 (TP53), transcript variant 2, mRNA.	273	Interaction with AXIN1 (By similarity).|Interaction with DNA.|Interaction with E4F1.|Interaction with HIPK1 (By similarity).		R -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> G (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation; abolishes sequence-specific DNA binding; dbSNP:rs28934576).|R -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions).|R -> P (in sporadic cancers; somatic mutation).|R -> Q (in sporadic cancers; somatic mutation).|R -> S (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> Y (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions).		DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|Ras protein signal transduction|activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to UV|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|determination of adult lifespan|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|regulation of mitochondrial membrane permeability|replicative senescence|response to X-ray|response to antibiotic|response to gamma radiation	PML body|cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|protein complex|replication fork	ATP binding|DNA strand annealing activity|RNA polymerase II transcription factor binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|histone acetyltransferase binding|p53 binding|protease binding|protein N-terminus binding|protein binding|protein heterodimerization activity|protein kinase binding|protein phosphatase 2A binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.R273H(1040)|p.R273C(471)|p.R273L(185)|p.V272M(75)|p.R273P(63)|p.V272L(26)|p.R273S(15)|p.R273G(9)|p.V272E(8)|p.0?(8)|p.V272A(7)|p.V272G(5)|p.R273fs*72(4)|p.V272fs*73(4)|p.V272V(4)|p.R273fs*33(3)|p.R273fs*32(3)|p.R273_C275delRVC(2)|p.R273fs*71(2)|p.E271_R273delEVR(2)|p.?(2)|p.L265_K305del41(2)|p.F270_D281del12(2)|p.V272_K292del21(2)|p.R273R(1)|p.E258fs*71(1)|p.S269fs*21(1)|p.V272>?(1)|p.V272fs*34(1)|p.V272fs*74(1)|p.R273*(1)		NS(16)|adrenal_gland(37)|autonomic_ganglia(16)|biliary_tract(273)|bone(108)|breast(2530)|central_nervous_system(1264)|cervix(68)|endometrium(223)|eye(24)|fallopian_tube(1)|gastrointestinal_tract_(site_indeterminate)(1)|genital_tract(16)|haematopoietic_and_lymphoid_tissue(1301)|kidney(96)|large_intestine(5124)|liver(897)|lung(2388)|meninges(5)|oesophagus(1473)|ovary(1659)|pancreas(452)|penis(10)|peritoneum(33)|pituitary(4)|placenta(1)|pleura(3)|prostate(235)|salivary_gland(43)|skin(791)|small_intestine(14)|soft_tissue(220)|stomach(1158)|testis(11)|thymus(21)|thyroid(54)|upper_aerodigestive_tract(2271)|urinary_tract(1259)|vagina(6)|vulva(79)	24185		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		GGCACAAACACGCACCTCAAA	0.542000	R273H(EN_ENDOMETRIUM)|R273H(HEC59_ENDOMETRIUM)|R273H(HEC6_ENDOMETRIUM)|R273H(HT29_LARGE_INTESTINE)|R273H(HT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273H(MDAMB468_BREAST)|R273H(MOLT13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273H(NCIH1155_LUNG)|R273H(NCIH1793_LUNG)|R273H(NCIH1975_LUNG)|R273H(NCIH2405_LUNG)|R273H(NCIH508_LARGE_INTESTINE)|R273H(OC314_OVARY)|R273H(PANC1_PANCREAS)|R273H(PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273H(SKMEL30_SKIN)|R273H(SNB19_CENTRAL_NERVOUS_SYSTEM)|R273H(SUDHL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273H(SUIT2_PANCREAS)|R273H(SUPT1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|R273H(SW1783_CENTRAL_NERVOUS_SYSTEM)|R273H(SW480_LARGE_INTESTINE)|R273H(SW620_LARGE_INTESTINE)|R273H(U251MG_CENTRAL_NERVOUS_SYSTEM)	111	"""Mis, N, F"""		"""breast, colorectal, lung, sarcoma, adrenocortical, glioma, multiple other tumour types"""	"""breast, sarcoma, adrenocortical carcinoma, glioma, multiple other tumour types"""		Other conserved DNA damage response genes	Osteosarcoma, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Breast-Ovarian Cancer, non-BRCA1/2;Hereditary Adrenocortical Cancer;Endometrial Cancer, Familial Clustering of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			24	8					0	0	1	0	0
PCDHB9	56127	broad.mit.edu	37	5	140568868	140568868	+	Silent	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr5:140568868C>T	uc003liw.1	+	1	1974	c.1974C>T	c.(1972-1974)caC>caT	p.H658H		NM_019119	NP_061992	Q9Y5E1	PCDB9_HUMAN	Homo sapiens protocadherin beta 9 (PCDHB9), mRNA.	659	Cadherin 6.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding							KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			CCACGCTGCACGTGCTCCTGG	0.706000													14	97					0	0	1	0	0
RHCG	51458	broad.mit.edu	37	15	90023572	90023572	+	Missense_Mutation	SNP	C	C	T	rs149510924	by1000genomes	TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr15:90023572C>T	uc002bnz.2	-	3	614	c.590G>A	c.(589-591)cGg>cAg	p.R197Q	RHCG_uc002boa.2_Non-coding_Transcript|RHCG_uc010bnq.1_Missense_Mutation_p.R81Q	NM_016321	NP_057405	Q9UBD6	RHCG_HUMAN	Homo sapiens Rh family, C glycoprotein (RHCG), mRNA.	197					amine transport|cellular ion homeostasis|epithelial cell differentiation|transepithelial ammonium transport	apical plasma membrane|basolateral plasma membrane|cytoplasmic vesicle|integral to plasma membrane	ammonia transmembrane transporter activity|ammonium transmembrane transporter activity|ankyrin binding	p.R197L(2)|p.R197Q(2)		breast(1)|endometrium(2)|kidney(2)|large_intestine(5)|lung(9)|upper_aerodigestive_tract(1)|urinary_tract(1)	21	Lung NSC(78;0.0237)|all_lung(78;0.0478)					GTAGAGGATCCGGGTCACTGT	0.557000													57	26					0	0	1	0	0
AK021933	0	broad.mit.edu	37	GL000195.1	31029	31029	+	RNA	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrGL000195.1:31029C>T	uc003woi.3	-	0		c.952G>A								Homo sapiens cDNA FLJ11871 fis, clone HEMBA1007052.																		CCTCCAGTGACGCGCACATTC	0.592000													3	5					0	0	1	0	0
LHFP	10186	broad.mit.edu	37	13	40175117	40175117	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr13:40175117G>A	uc001uxf.3	-	1	748	c.237C>T	c.(235-237)agC>agT	p.S79S		NM_005780	NP_005771	Q9Y693	LHFP_HUMAN	Homo sapiens lipoma HMGIC fusion partner (LHFP), mRNA.	79						integral to membrane	DNA binding		HMGA2/LHFP(2)	breast(1)|endometrium(2)|large_intestine(1)|liver(1)|lung(6)|prostate(2)	13		Lung NSC(96;3.55e-06)|Breast(139;0.00408)|Ovarian(182;0.0107)|Prostate(109;0.0118)|Lung SC(185;0.0719)|Hepatocellular(188;0.114)		OV - Ovarian serous cystadenocarcinoma(117;6.48e-46)|Epithelial(112;8.43e-42)|all cancers(112;1.42e-36)|GBM - Glioblastoma multiforme(144;0.00187)|BRCA - Breast invasive adenocarcinoma(63;0.00886)|KIRC - Kidney renal clear cell carcinoma(186;0.048)|Kidney(163;0.0601)|LUSC - Lung squamous cell carcinoma(192;0.105)		TCCATTCTGCGCTGGGGATGC	0.597000			T	HMGA2	lipoma								144	47					0	0	1	0	0
CYP11B2	1585	broad.mit.edu	37	8	143996607	143996607	+	Silent	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr8:143996607C>A	uc003yxk.1	-	2	453	c.450G>T	c.(448-450)tcG>tcT	p.S150S		NM_000498	NP_000489	P19099	C11B2_HUMAN	Homo sapiens cytochrome P450, family 11, subfamily B, polypeptide 2 (CYP11B2), nuclear gene encoding mitochondrial protein, mRNA.	150					aldosterone biosynthetic process|cellular response to hormone stimulus|cellular response to potassium ion|cortisol biosynthetic process|potassium ion homeostasis|regulation of blood volume by renal aldosterone|sodium ion homeostasis|xenobiotic metabolic process		corticosterone 18-monooxygenase activity|electron carrier activity|steroid 11-beta-monooxygenase activity			cervix(1)|endometrium(2)|kidney(3)|large_intestine(5)|lung(22)|ovary(3)|upper_aerodigestive_tract(3)	39	all_cancers(97;5.56e-11)|all_epithelial(106;2.49e-08)|Lung NSC(106;0.000228)|all_lung(105;0.000633)|Medulloblastoma(13;0.00276)|all_neural(13;0.00559)|Ovarian(258;0.0254)|Acute lymphoblastic leukemia(118;0.155)				Candesartan(DB00796)|Metyrapone(DB01011)	CGGCCTTGGGCGACAGCACAT	0.637000									Familial Hyperaldosteronism type I				7	71					0	0	1	0	0
HIVEP2	3097	broad.mit.edu	37	6	143091566	143091566	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr6:143091566C>T	uc003qjd.3	-	4	5053	c.4310G>A	c.(4309-4311)gGt>gAt	p.G1437D		NM_006734	NP_006725	P31629	ZEP2_HUMAN	Homo sapiens human immunodeficiency virus type I enhancer binding protein 2 (HIVEP2), mRNA.	1437					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(2)|breast(4)|central_nervous_system(6)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(19)|lung(35)|ovary(4)|prostate(6)|skin(4)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	100				OV - Ovarian serous cystadenocarcinoma(155;1.61e-05)|GBM - Glioblastoma multiforme(68;0.0102)		TCGCTTGCTACCTCCCAGGGT	0.512000													26	33					0	0	1	0	0
KIAA1045	23349	broad.mit.edu	37	9	34978096	34978096	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr9:34978096G>A	uc003zvq.3	+	7	1369	c.1191G>A	c.(1189-1191)aaG>aaA	p.K397K	KIAA1045_uc003zvr.3_Silent_p.K397K	NM_015297	NP_056112	Q9UPV7	K1045_HUMAN	Homo sapiens KIAA1045 (KIAA1045), mRNA.	397							calcium ion binding			breast(1)|endometrium(1)|kidney(1)|large_intestine(7)|lung(4)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	19			LUSC - Lung squamous cell carcinoma(32;0.00575)			TTCACCTGAAGCCCCCAGGAT	0.557000													14	79					0	0	1	0	0
SS18L1	26039	broad.mit.edu	37	20	60736500	60736500	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr20:60736500G>A	uc011aaa.1	+	3	295	c.240G>A	c.(238-240)acG>acA	p.T80T	SS18L1_uc002ybz.1_Non-coding_Transcript|SS18L1_uc002yca.1_Non-coding_Transcript|SS18L1_uc002ycb.3_Silent_p.T80T|SS18L1_uc002ycc.1_Non-coding_Transcript	NM_198935	NP_945173	O75177	CREST_HUMAN	Homo sapiens synovial sarcoma translocation gene on chromosome 18-like 1 (SS18L1), mRNA.	80	N-terminal auto-inhibitory domain; necessary for interaction with SMARCA4/BRG1 (By similarity).				chromatin modification|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	condensed chromosome kinetochore			SS18L1/SSX1(2)	ovary(2)|skin(1)	3	Breast(26;3.97e-09)		BRCA - Breast invasive adenocarcinoma(19;1.92e-08)			AGCCGCCCACGCAGAACATGA	0.622000			T	SSX1	synovial sarcoma								27	52					0	0	1	0	0
BC071797	0	broad.mit.edu	37	1	142803562	142803562	+	Splice_Site	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:142803562G>A	uc001ejc.3	+	1		c.32_splice	c.e1+1		CR936796_uc001eiw.1_Intron|BC053679_uc001ejb.3_Non-coding_Transcript					Homo sapiens, clone IMAGE:4720764, mRNA.																		TCTGCAGTCAGGTAAGATTTC	0.259000													5	158					0	0	1	0	0
SHOX	6473	broad.mit.edu	37	X	601571	601571	+	Silent	SNP	C	C	A	rs137852557		TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrX:601571C>A	uc004cph.1	+	3	1193	c.502C>A	c.(502-504)Cgg>Agg	p.R168R	SHOX_uc004cpi.3_Silent_p.R168R	NM_000451	NP_000442	O15266	SHOX_HUMAN	Homo sapiens short stature homeobox (SHOX), transcript variant 1, mRNA.	168			R -> W (in LMD).		skeletal system development|transcription from RNA polymerase II promoter	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity	p.R168R(1)|p.R168Q(1)		endometrium(3)|lung(9)|prostate(1)	13		all_cancers(21;4.28e-07)|all_epithelial(21;2.07e-08)|all_lung(23;2.81e-05)|Lung NSC(23;0.000693)|Lung SC(21;0.122)				GTTCCAGAACCGGAGAGCCAA	0.592000													5	74					0	0	1	0	0
BTNL2	56244	broad.mit.edu	37	6	32362585	32362585	+	Missense_Mutation	SNP	G	G	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr6:32362585G>T	uc003obg.1	-	5	1296	c.1296C>A	c.(1294-1296)gaC>gaA	p.D432E	BTNL2_uc010jty.1_Missense_Mutation_p.D155E|BTNL2_uc010jtz.1_Non-coding_Transcript|BTNL2_uc010jua.1_Missense_Mutation_p.D222E	NM_019602	NP_062548	Q9UIR0	BTNL2_HUMAN	Homo sapiens butyrophilin-like 2 (MHC class II associated) (BTNL2), mRNA.	432						integral to membrane		p.D432D(2)		central_nervous_system(3)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(5)|lung(5)|prostate(1)|urinary_tract(1)	19						AACAAGTGACGTCCACAGCGG	0.498000													14	78					0	0	1	0	0
LNPEP	4012	broad.mit.edu	37	5	96360368	96360368	+	Missense_Mutation	SNP	A	A	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr5:96360368A>G	uc003kmv.1	+	14	3219	c.2705A>G	c.(2704-2706)gAt>gGt	p.D902G	LNPEP_uc003kmw.1_Missense_Mutation_p.D888G	NM_005575	NP_787116	Q9UIQ6	LCAP_HUMAN	Homo sapiens leucyl/cystinyl aminopeptidase (LNPEP), transcript variant 1, mRNA.	902					cell-cell signaling|female pregnancy|proteolysis	extracellular region|integral to plasma membrane	aminopeptidase activity|metallopeptidase activity|zinc ion binding			breast(2)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(9)|lung(10)|ovary(3)|skin(1)|urinary_tract(1)	34		all_cancers(142;7e-07)|all_epithelial(76;9.52e-10)|all_lung(232;0.00101)|Lung NSC(167;0.00137)|Ovarian(225;0.024)|Colorectal(57;0.0269)|Breast(839;0.244)		COAD - Colon adenocarcinoma(37;0.072)		AGCTCAGAGGATGTGCGGAAG	0.408000													11	20					0	0	1	0	0
SGSH	6448	broad.mit.edu	37	17	78184304	78184304	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:78184304C>T	uc002jxz.4	-	7	1543	c.1456G>A	c.(1456-1458)Gtc>Atc	p.V486I	SGSH_uc002jya.4_Missense_Mutation_p.V283I|SGSH_uc002jxy.2_3'UTR	NM_000199	NP_000190	P51688	SPHM_HUMAN	Homo sapiens N-sulfoglucosamine sulfohydrolase (SGSH), mRNA.	486			V -> F (in MPS3A).		proteoglycan metabolic process	lysosome	N-sulfoglucosamine sulfohydrolase activity|metal ion binding|sulfuric ester hydrolase activity			central_nervous_system(1)|large_intestine(1)|lung(2)|ovary(1)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	10	all_neural(118;0.0952)		OV - Ovarian serous cystadenocarcinoma(97;0.0292)|BRCA - Breast invasive adenocarcinoma(99;0.0908)			TCCTCCAGGACGCCGTCGGGG	0.652000													5	15					0	0	1	0	0
PTCHD4	442213	broad.mit.edu	37	6	47847228	47847228	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr6:47847228C>T	uc011dwm.2	-	2	1386	c.1352G>A	c.(1351-1353)cGt>cAt	p.R451H	PTCHD4_uc011dwn.2_Missense_Mutation_p.R198H	NM_001013732	NP_001013754	Q6ZW05	CF138_HUMAN	Homo sapiens chromosome 6 open reading frame 138 (C6orf138), transcript variant 1, mRNA.	451						integral to membrane	hedgehog receptor activity										ATAATGTTCACGGAGGAAGTG	0.448000													12	30					0	0	1	0	0
B4GALNT3	283358	broad.mit.edu	37	12	667810	667810	+	Missense_Mutation	SNP	C	C	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr12:667810C>G	uc001qii.1	+	17	2744	c.2744C>G	c.(2743-2745)aCc>aGc	p.T915S	B4GALNT3_uc001qik.1_Missense_Mutation_p.T464S	NM_173593	NP_775864	Q6L9W6	B4GN3_HUMAN	Homo sapiens beta-1,4-N-acetyl-galactosaminyl transferase 3 (B4GALNT3), mRNA.	915						Golgi cisterna membrane|integral to membrane	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity			breast(1)|central_nervous_system(1)|endometrium(6)|kidney(3)|large_intestine(1)|lung(10)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	26	all_cancers(10;0.0158)|all_epithelial(11;0.0274)|Ovarian(42;0.0512)|all_lung(10;0.154)|Lung NSC(10;0.215)		OV - Ovarian serous cystadenocarcinoma(31;0.00018)|BRCA - Breast invasive adenocarcinoma(9;0.0262)			TGTGGGGCCACCCCCCAGTGG	0.567000													9	30					0	0	1	0	0
ANXA10	11199	broad.mit.edu	37	4	169049237	169049237	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr4:169049237G>A	uc003irm.3	+	1	185	c.21G>A	c.(19-21)gtG>gtA	p.V7V		NM_007193	NP_009124	Q9UJ72	ANX10_HUMAN	Homo sapiens annexin A10 (ANXA10), mRNA.	7							calcium ion binding|calcium-dependent phospholipid binding			endometrium(1)|kidney(2)|large_intestine(4)|lung(6)|prostate(1)|stomach(2)	16		Prostate(90;0.00876)|Renal(120;0.0183)|all_neural(102;0.0837)|Melanoma(52;0.132)		GBM - Glioblastoma multiforme(119;0.0325)		CCCACCAGGTGCAAGGAACCA	0.433000													10	15					0	0	1	0	0
BC080605	0	broad.mit.edu	37	9	68414292	68414292	+	RNA	SNP	G	G	A	rs142049020		TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr9:68414292G>A	uc004aex.3	+	0		c.847G>A								Homo sapiens mRNA; cDNA DKFZp564N0763 (from clone DKFZp564N0763).																		agacttgcaagtctctcactt	0.438000													4	25					0	0	1	0	0
KIAA1211	57482	broad.mit.edu	37	4	57193840	57193840	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr4:57193840C>T	uc003hbk.2	+	10	3963	c.3572C>T	c.(3571-3573)cCg>cTg	p.P1191L	KIAA1211_uc010iha.2_Missense_Mutation_p.P1184L	NM_020722	NP_065773	Q6ZU35	K1211_HUMAN	Homo sapiens KIAA1211 (KIAA1211), mRNA.	1191										endometrium(7)|large_intestine(10)|lung(39)|ovary(2)|prostate(3)|skin(3)|stomach(1)	65	Glioma(25;0.08)|all_neural(26;0.101)					CCCCCAGCGCCGCTGGTAAAA	0.483000													62	76					0	0	1	0	0
BC063132	0	broad.mit.edu	37	GL000241.1	25528	25528	+	RNA	SNP	T	T	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrGL000241.1:25528T>G	uc011mgv.2	-	3		c.464A>C								Homo sapiens cDNA clone IMAGE:4673444, containing frame-shift errors.																		AGTGCATGTATATAGGTTCCC	0.388000													10	323					0	0	1	0	0
C1orf177	163747	broad.mit.edu	37	1	55277787	55277787	+	Silent	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:55277787C>A	uc001cyb.4	+	5	741	c.687C>A	c.(685-687)gtC>gtA	p.V229V	C1orf177_uc001cya.4_Silent_p.V229V	NM_001110533	NP_001104003	Q3ZCV2	CA177_HUMAN	Homo sapiens chromosome 1 open reading frame 177 (C1orf177), transcript variant 2, mRNA.	229										breast(1)|cervix(1)|kidney(1)|large_intestine(6)|lung(6)|prostate(2)	17						CACGATCCGTCGGCACCCGCG	0.587000													20	67					0	0	1	0	0
OR5D14	219436	broad.mit.edu	37	11	55563417	55563417	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr11:55563417G>A	uc010rim.2	+	0	386	c.386G>A	c.(385-387)tGc>tAc	p.C129Y		NM_001004735	NP_001004735	Q8NGL3	OR5DE_HUMAN	Homo sapiens olfactory receptor, family 5, subfamily D, member 14 (OR5D14), mRNA.	129					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(30)|ovary(2)|prostate(1)|skin(2)|stomach(3)|urinary_tract(1)	48		all_epithelial(135;0.196)				GTGGCCATCTGCAATCCTCTG	0.532000													7	50					0	0	1	0	0
KDELR2	11014	broad.mit.edu	37	7	6509337	6509337	+	Missense_Mutation	SNP	T	T	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr7:6509337T>G	uc003sqe.4	-	2	402	c.241A>C	c.(241-243)Aaa>Caa	p.K81Q	DAGLB_uc003sqd.4_Intron|KDELR2_uc003sqf.4_Missense_Mutation_p.K81Q	NM_006854	NP_006845	P33947	ERD22_HUMAN	Homo sapiens KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (KDELR2), transcript variant 1, mRNA.	81					intracellular protein transport|protein retention in ER lumen|vesicle-mediated transport	Golgi apparatus|endoplasmic reticulum membrane|integral to membrane	KDEL sequence binding|protein binding|receptor activity			central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(5)|ovary(1)	10		Ovarian(82;0.0776)		UCEC - Uterine corpus endometrioid carcinoma (126;0.101)		GCCTTAAATTTCAGGTAGATC	0.443000													21	66					0	0	1	0	0
SERPINB9	5272	broad.mit.edu	37	6	2893765	2893765	+	Silent	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr6:2893765C>T	uc003mug.3	-	4	568	c.447G>A	c.(445-447)ccG>ccA	p.P149P	AY927512_uc003mue.3_Intron|SERPINB9_uc003muf.3_5'Flank	NM_004155	NP_004146	P50453	SPB9_HUMAN	Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 9 (SERPINB9), mRNA.	149					anti-apoptosis|cellular response to estrogen stimulus|immune response|mast cell mediated immunity|regulation of proteolysis	cytosol|extracellular space|nucleus	caspase inhibitor activity|protease binding|serine-type endopeptidase inhibitor activity			breast(1)|endometrium(4)|large_intestine(3)|lung(5)|pancreas(1)|prostate(1)	15	Ovarian(93;0.0412)	all_hematologic(90;0.108)				TTGAGCTACCCGGCAACAACT	0.393000													39	13					0	0	1	0	0
CD1D	912	broad.mit.edu	37	1	158152703	158152703	+	Missense_Mutation	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:158152703C>A	uc001frr.3	+	4	1142	c.643C>A	c.(643-645)Cct>Act	p.P215T	CD1D_uc009wss.3_Intron	NM_001766	NP_001757	P15813	CD1D_HUMAN	Homo sapiens CD1d molecule (CD1D), mRNA.	215	Ig-like.				T cell selection|antigen processing and presentation, endogenous lipid antigen via MHC class Ib|detection of bacterium|innate immune response|interspecies interaction between organisms|positive regulation of innate immune response	endosome membrane|integral to plasma membrane|lysosomal membrane	beta-2-microglobulin binding|exogenous lipid antigen binding|histone binding			endometrium(1)|kidney(2)|large_intestine(2)|lung(19)|ovary(1)|prostate(3)|urinary_tract(2)	30	all_hematologic(112;0.0378)					TGGCCCCAGTCCTGGCCCTGG	0.592000													20	65					0	0	1	0	0
LRRC4B	94030	broad.mit.edu	37	19	51022478	51022478	+	Nonsense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr19:51022478C>T	uc002pss.3	-	2	629	c.492G>A	c.(490-492)tgG>tgA	p.W164*		NM_001080457	NP_001073926	Q9NT99	LRC4B_HUMAN	Homo sapiens leucine rich repeat containing 4B (LRRC4B), mRNA.	164						cell junction|integral to membrane|presynaptic membrane				breast(1)|central_nervous_system(1)|endometrium(4)|large_intestine(6)|liver(1)|lung(11)|prostate(4)|skin(1)|urinary_tract(1)	30		all_neural(266;0.131)		OV - Ovarian serous cystadenocarcinoma(262;0.00284)|GBM - Glioblastoma multiforme(134;0.0188)		TGTTCCGCAGCCAGAGCTCCC	0.652000													40	53					0	0	1	0	0
FAM49A	81553	broad.mit.edu	37	2	16742751	16742751	+	Silent	SNP	G	G	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr2:16742751G>T	uc010exm.2	-	5	634	c.486C>A	c.(484-486)atC>atA	p.I162I	FAM49A_uc002rck.2_Silent_p.I162I	NM_030797	NP_110424	Q9H0Q0	FA49A_HUMAN	Homo sapiens family with sequence similarity 49, member A (FAM49A), mRNA.	162						intracellular				breast(1)|central_nervous_system(1)|kidney(1)|large_intestine(4)|liver(1)|lung(11)|skin(3)|upper_aerodigestive_tract(1)	23	Acute lymphoblastic leukemia(172;0.0734)|all_hematologic(175;0.088)		GBM - Glioblastoma multiforme(3;0.00969)			GGTTGCGACTGATTGTTCTTC	0.493000													9	42					0	0	1	0	0
SLC43A1	8501	broad.mit.edu	37	11	57281459	57281459	+	Missense_Mutation	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr11:57281459G>C	uc001nkk.3	-	1	244	c.126C>G	c.(124-126)aaC>aaG	p.N42K	SLC43A1_uc001nkl.3_Missense_Mutation_p.N42K	NM_001198810	NP_001185739	O75387	LAT3_HUMAN	Homo sapiens solute carrier family 43, member 1 (SLC43A1), transcript variant 2, mRNA.	42					cellular nitrogen compound metabolic process|ion transport	integral to plasma membrane	neutral amino acid transmembrane transporter activity			breast(1)|endometrium(2)|large_intestine(5)|liver(1)|lung(6)|ovary(1)|skin(1)|upper_aerodigestive_tract(2)	19						AGAAGCCCTCGTTCTTCAGAA	0.597000													19	3					0	0	1	0	0
LARP4B	23185	broad.mit.edu	37	10	909780	909780	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:909780G>A	uc001ifs.1	-	3	374	c.333C>T	c.(331-333)gcC>gcT	p.A111A		NM_015155	NP_055970	Q92615	LAR4B_HUMAN	Homo sapiens La ribonucleoprotein domain family, member 4B (LARP4B), mRNA.	111							RNA binding|nucleotide binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(13)|lung(13)|ovary(2)|skin(2)|urinary_tract(2)	38						CTGGCAATGCGGCATTCTCAT	0.507000													49	48					0	0	1	0	0
PYY	5697	broad.mit.edu	37	17	42030806	42030806	+	Missense_Mutation	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:42030806G>C	uc002ieq.3	-	4	587	c.46C>G	c.(46-48)Ctg>Gtg	p.L16V	PYY_uc002ier.1_Missense_Mutation_p.L16V	NM_004160	NP_004151	P10082	PYY_HUMAN	Homo sapiens peptide YY (PYY), mRNA.	16					G-protein coupled receptor protein signaling pathway|cell proliferation|cell-cell signaling|cellular component movement|cytoskeleton organization|digestion	soluble fraction				endometrium(1)|ovary(1)	2		Breast(137;0.00314)|Prostate(33;0.0724)		BRCA - Breast invasive adenocarcinoma(366;0.12)		AGCAGGGCCAGAAGCACTGTG	0.662000													4	22					0	0	1	0	0
MPHOSPH9	10198	broad.mit.edu	37	12	123703047	123703047	+	Splice_Site	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr12:123703047C>A	uc001uel.3	-	2	525	c.417_splice	c.e2-1	p.S139_splice	MPHOSPH9_uc010tal.2_Splice_Site|MPHOSPH9_uc010tam.2_Splice_Site|MPHOSPH9_uc001uem.3_Splice_Site	NM_022782	NP_073619	Q99550	MPP9_HUMAN	Homo sapiens M-phase phosphoprotein 9 (MPHOSPH9), mRNA.	139					M phase of mitotic cell cycle	Golgi membrane|centriole				NS(1)|breast(1)|endometrium(4)|kidney(1)|large_intestine(5)|lung(18)|prostate(2)|skin(1)	33	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.000182)|Epithelial(86;0.00046)|BRCA - Breast invasive adenocarcinoma(302;0.169)		TATAGCATTACTATTTAAGAA	0.398000													9	76					0	0	1	0	0
MARCH8	220972	broad.mit.edu	37	10	45954693	45954693	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:45954693G>A	uc001jci.1	-	5	685	c.446C>T	c.(445-447)tCc>tTc	p.S149F	MARCH8_uc001jch.2_Missense_Mutation_p.S431F|MARCH8_uc001jcj.1_Missense_Mutation_p.S149F|MARCH8_uc001jck.1_Missense_Mutation_p.S149F|DL492557_uc001jcf.3_5'Flank|MARCH8_uc001jcg.1_Missense_Mutation_p.S18F	NM_001002266	NP_659458	Q5T0T0	MARH8_HUMAN	Homo sapiens membrane-associated ring finger (C3HC4) 8 (MARCH8), transcript variant 7, mRNA.	149						cytoplasmic vesicle membrane|early endosome membrane|integral to membrane|lysosomal membrane	ubiquitin-protein ligase activity|zinc ion binding			endometrium(2)|kidney(1)|large_intestine(5)|lung(4)	12						GCGCTCGCTGGACGTCATCTG	0.532000													17	96					0	0	1	0	0
MKI67	4288	broad.mit.edu	37	10	129905831	129905831	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:129905831C>T	uc001lke.3	-	12	4468	c.4273G>A	c.(4273-4275)Gga>Aga	p.G1425R	MKI67_uc001lkf.3_Missense_Mutation_p.G1065R|MKI67_uc009yav.1_Missense_Mutation_p.G1000R|MKI67_uc009yaw.1_Missense_Mutation_p.G575R	NM_002417	NP_002408	P46013	KI67_HUMAN	Homo sapiens antigen identified by monoclonal antibody Ki-67 (MKI67), transcript variant 1, mRNA.	1425	16 X 122 AA approximate repeats.				cell proliferation	nucleolus	ATP binding|protein C-terminus binding			NS(2)|autonomic_ganglia(1)|breast(2)|central_nervous_system(2)|cervix(2)|endometrium(14)|haematopoietic_and_lymphoid_tissue(5)|kidney(7)|large_intestine(30)|lung(64)|ovary(4)|pancreas(1)|prostate(4)|skin(2)|soft_tissue(1)|stomach(10)|upper_aerodigestive_tract(4)|urinary_tract(4)	159		all_epithelial(44;2.12e-05)|all_lung(145;0.00679)|Lung NSC(174;0.00998)|all_neural(114;0.0936)|Colorectal(57;0.14)|Breast(234;0.166)|Melanoma(40;0.203)				TCCTCACCTCCTGGTACTTTA	0.478000													6	246					0	0	1	0	0
C14orf49	161176	broad.mit.edu	37	14	95921744	95921744	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr14:95921744G>A	uc001yei.4	-	4	1122	c.1107C>T	c.(1105-1107)gaC>gaT	p.D369D	C14orf49_uc010avi.3_Silent_p.D369D|C14orf49_uc001yej.1_Silent_p.D369D	NM_152592	NP_689805	Q6ZMZ3	SYNE3_HUMAN	Homo sapiens chromosome 14 open reading frame 49 (C14orf49), mRNA.	369					cytoskeletal anchoring at nuclear membrane	SUN-KASH complex|integral to membrane|nuclear outer membrane	actin binding			breast(3)|central_nervous_system(1)|endometrium(2)|large_intestine(6)|lung(27)|prostate(5)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	50		all_cancers(154;0.0937)		COAD - Colon adenocarcinoma(157;0.245)		CCACCAGCTCGTCCTCGGTCC	0.642000													8	29					0	0	1	0	0
BC080605	0	broad.mit.edu	37	9	68414259	68414259	+	RNA	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr9:68414259C>T	uc004aex.3	+	0		c.814C>T								Homo sapiens mRNA; cDNA DKFZp564N0763 (from clone DKFZp564N0763).																		ccacagtggcctcaaagaact	0.483000													3	26					0	0	1	0	0
BC080605	0	broad.mit.edu	37	9	68414371	68414371	+	RNA	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr9:68414371C>T	uc004aex.3	+	0		c.926C>T								Homo sapiens mRNA; cDNA DKFZp564N0763 (from clone DKFZp564N0763).																		gagaagtcaacacttggcttc	0.418000													4	15					0	0	1	0	0
FAM86EP	348926	broad.mit.edu	37	4	3952899	3952899	+	RNA	SNP	A	A	T	rs17410906		TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr4:3952899A>T	uc011bvu.2	-	2		c.209T>A			FAM86EP_uc003ghn.3_Intron					Homo sapiens family with sequence similarity 86, member E, pseudogene (FAM86EP), non-coding RNA.																		AGCACCGGGCATACTTGACTG	0.557000													4	51					0	0	1	0	0
BAGE1	0	broad.mit.edu	37	GL000237.1	407	407	+	RNA	SNP	A	A	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrGL000237.1:407A>G	uc011mgu.1	-	1		c.811T>C								Homo sapiens B melanoma antigen variant f (BAGE1) mRNA, complete cds, alternatively spliced.																		atcccatgacaccaaaaccca	0.463000													3	11					0	0	1	0	0
NT5C1B-RDH14	100526794	broad.mit.edu	37	2	18736500	18736500	+	Missense_Mutation	SNP	T	T	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr2:18736500T>G	uc010exr.3	-	8	2022	c.1910A>C	c.(1909-1911)aAa>aCa	p.K637T	NT5C1B-RDH14_uc002rcy.3_3'UTR|NT5C1B-RDH14_uc002rcx.4_Missense_Mutation_p.K323T	NM_001199103	NP_001186032	Q96P26	5NT1B_HUMAN	Homo sapiens NT5C1B-RDH14 readthrough (NT5C1B-RDH14), transcript variant 1, mRNA.	0					purine base metabolic process|purine nucleotide catabolic process	cytosol	5'-nucleotidase activity|magnesium ion binding|nucleotide binding										ATCCCAGAGTTTTCTTGCAAC	0.413000													33	71					0	0	1	0	0
HBA1	3039	broad.mit.edu	37	16	227404	227404	+	Nonsense_Mutation	SNP	C	C	A	rs121913128		TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr16:227404C>A	uc002cfx.1	+	2	460	c.423C>A	c.(421-423)taC>taA	p.Y141*	HBQ1_uc002cfz.3_5'Flank	NM_000558	NP_000549	P69905	HBA_HUMAN	Homo sapiens hemoglobin, alpha 1 (HBA1), mRNA.	141			Y -> H (in Rouen/Ethiopia; O(2) affinity up).		hydrogen peroxide catabolic process|positive regulation of cell death|protein heterooligomerization	cytosolic small ribosomal subunit|haptoglobin-hemoglobin complex|hemoglobin complex	heme binding|oxygen binding|oxygen transporter activity|protein binding			lung(1)	1		all_cancers(16;2.03e-06)|all_epithelial(16;5.16e-06)|Hepatocellular(16;0.000325)|Lung NSC(18;0.0138)|all_lung(18;0.0306)			Amodiaquine(DB00613)|Chloroquine(DB00608)|Iron Dextran(DB00893)|Mefloquine(DB00358)|Primaquine(DB01087)|Quinine(DB00468)	CCTCCAAATACCGTTAAGCTG	0.647000											OREG0003687	type=REGULATORY REGION|Gene=SERPINB9|Dataset=Stanford ENCODE Dataset|EvidenceSubtype=Transient transfection luciferase assay	5	17					0	0	1	0	0
GRXCR1	389207	broad.mit.edu	37	4	42895339	42895339	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr4:42895339G>A	uc003gwt.3	+	0	57	c.56G>A	c.(55-57)cGg>cAg	p.R19Q		NM_001080476	NP_001073945	A8MXD5	GRCR1_HUMAN	Homo sapiens glutaredoxin, cysteine rich 1 (GRXCR1), mRNA.	19					cell redox homeostasis|inner ear receptor stereocilium organization|sensory perception of sound|vestibular receptor cell development	kinocilium|stereocilium	electron carrier activity|protein disulfide oxidoreductase activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(22)|ovary(1)|prostate(2)|skin(1)	32						GTCCGGTTTCGGATCGCGTCC	0.512000													19	105					0	0	1	0	0
TRHR	7201	broad.mit.edu	37	8	110131681	110131681	+	Missense_Mutation	SNP	T	T	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr8:110131681T>A	uc003ymz.4	+	1	1283	c.1194T>A	c.(1192-1194)agT>agA	p.S398R		NM_003301	NP_003292	P34981	TRFR_HUMAN	Homo sapiens thyrotropin-releasing hormone receptor (TRHR), mRNA.	398						integral to plasma membrane	thyrotropin-releasing hormone receptor activity			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(8)|lung(12)|prostate(4)|skin(4)|urinary_tract(1)	37			OV - Ovarian serous cystadenocarcinoma(57;2.3e-11)			TTAGCCAAAGTTGATTCATGA	0.403000													12	80					0	0	1	0	0
ZNF792	126375	broad.mit.edu	37	19	35448925	35448925	+	Missense_Mutation	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr19:35448925G>C	uc002nxh.1	-	3	2221	c.1834C>G	c.(1834-1836)Cag>Gag	p.Q612E		NM_175872	NP_787068	Q3KQV3	ZN792_HUMAN	Homo sapiens zinc finger protein 792 (ZNF792), mRNA.	612					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			cervix(1)|endometrium(4)|kidney(1)|large_intestine(1)|lung(5)	12	all_lung(56;4.18e-08)|Lung NSC(56;6.62e-08)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0849)			ACAGCGCCCTGATAAGGTCTG	0.488000													10	17					0	0	1	0	0
CNTN4	152330	broad.mit.edu	37	3	3076369	3076369	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr3:3076369G>A	uc003bpc.3	+	16	2176	c.1837G>A	c.(1837-1839)Gct>Act	p.A613T	CNTN4_uc003bpb.1_Missense_Mutation_p.A284T|CNTN4_uc021wsg.1_Missense_Mutation_p.A613T|CNTN4_uc003bpd.1_Missense_Mutation_p.A613T|CNTN4_uc003bpe.3_Missense_Mutation_p.A285T|CNTN4_uc003bpf.3_Missense_Mutation_p.A284T	NM_175607	NP_783302	Q8IWV2	CNTN4_HUMAN	Homo sapiens contactin 4 (CNTN4), transcript variant 1, mRNA.	613	Fibronectin type-III 1.				axon guidance|axonal fasciculation|brain development|negative regulation of neuron differentiation|neuron cell-cell adhesion|regulation of synaptic plasticity	anchored to membrane|axon|extracellular region|plasma membrane	protein binding			NS(1)|breast(4)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(14)|lung(19)|ovary(2)|pancreas(4)|skin(7)|upper_aerodigestive_tract(1)|urinary_tract(1)	61		Ovarian(110;0.156)		Epithelial(13;0.000695)|all cancers(10;0.0047)|OV - Ovarian serous cystadenocarcinoma(96;0.01)		AGATACCACTGCTCAGCTCTC	0.552000													25	38					0	0	1	0	0
CPA4	51200	broad.mit.edu	37	7	129950692	129950692	+	Missense_Mutation	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr7:129950692G>C	uc003vpr.3	+	8	906	c.859G>C	c.(859-861)Gag>Cag	p.E287Q	CPA4_uc011kpd.2_Missense_Mutation_p.E254Q|CPA4_uc011kpe.2_Missense_Mutation_p.E183Q	NM_016352	NP_057436	Q9UI42	CBPA4_HUMAN	Homo sapiens carboxypeptidase A4 (CPA4), transcript variant 1, mRNA.	287					histone acetylation|proteolysis	extracellular region	metallocarboxypeptidase activity|zinc ion binding			central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(10)|ovary(1)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	21	Melanoma(18;0.0435)					TTCGGAAGTGGAGGTGAAATC	0.493000													26	71					0	0	1	0	0
BC101079	0	broad.mit.edu	37	15	102292797	102292797	+	Missense_Mutation	SNP	C	C	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr15:102292797C>G	uc010usj.2	+	3	444	c.385C>G	c.(385-387)Cca>Gca	p.P129A	DQ597539_uc002bxo.3_Non-coding_Transcript|DQ593624_uc002bxp.4_5'Flank|DQ576888_uc021sxy.1_5'Flank|DQ596486_uc002bxz.4_5'Flank|DQ582294_uc021syc.1_5'Flank|DQ595661_uc021sye.1_5'Flank|DQ588439_uc002byd.3_5'Flank|DQ593353_uc002bye.3_5'Flank|DQ597703_uc002byf.1_5'Flank|DQ585237_uc002byg.3_5'Flank|DQ588452_uc021syg.1_5'Flank|DQ586526_uc002byi.3_5'Flank|DQ588428_uc002byk.3_5'Flank|DQ597703_uc002bym.3_5'Flank|DQ571896_uc010usm.2_5'Flank|DQ586526_uc021syh.1_5'Flank|DQ588425_uc002byr.3_5'Flank					Homo sapiens cDNA clone IMAGE:40009338.									p.P129A(2)									GAGCTGCTGTCCAACCTGCAC	0.597000													3	37					0	0	1	0	0
TTLL6	284076	broad.mit.edu	37	17	46847315	46847315	+	Nonsense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:46847315G>A	uc021tzm.1	-	13	2220	c.2185C>T	c.(2185-2187)Cag>Tag	p.Q729*	TTLL6_uc002iob.3_Nonsense_Mutation_p.Q422*|TTLL6_uc010dbi.3_Intron|TTLL6_uc002ioc.3_Nonsense_Mutation_p.Q482*|TTLL6_uc002iod.3_Intron	NM_001130918	NP_001124390	Q8N841	TTLL6_HUMAN	Homo sapiens tubulin tyrosine ligase-like family, member 6 (TTLL6), transcript variant 1, mRNA.	681						cilium|microtubule basal body	ATP binding|tubulin binding|tubulin-tyrosine ligase activity			endometrium(1)|large_intestine(5)|lung(9)|prostate(1)|skin(2)	18						GGGGTCTGCTGCTTCTTGCAT	0.502000													12	105					0	0	1	0	0
SAMD4B	55095	broad.mit.edu	37	19	39868449	39868449	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr19:39868449C>T	uc002olb.3	+	9	2464	c.1429C>T	c.(1429-1431)Cgg>Tgg	p.R477W	SAMD4B_uc002ola.3_Missense_Mutation_p.R477W	NM_018028	NP_060498	Q5PRF9	SMAG2_HUMAN	Homo sapiens sterile alpha motif domain containing 4B (SAMD4B), mRNA.	477							protein binding			autonomic_ganglia(1)|breast(1)|endometrium(5)|large_intestine(1)|lung(4)|skin(1)|urinary_tract(2)	15	all_cancers(60;2.5e-07)|all_lung(34;4.03e-08)|Lung NSC(34;4.66e-08)|all_epithelial(25;6.4e-07)|Ovarian(47;0.0512)		Epithelial(26;9.6e-28)|all cancers(26;9.14e-25)|Lung(45;0.000168)|LUSC - Lung squamous cell carcinoma(53;0.000199)			CCAGTTTACACGGGTGATGGG	0.592000													21	51					0	0	1	0	0
MTR	4548	broad.mit.edu	37	1	237016332	237016332	+	Missense_Mutation	SNP	G	G	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:237016332G>T	uc001hyi.4	+	17	2320	c.1897G>T	c.(1897-1899)Gat>Tat	p.D633Y	MTR_uc010pxw.2_Missense_Mutation_p.D226Y|MTR_uc010pxx.2_Missense_Mutation_p.D633Y|MTR_uc010pxy.2_Intron	NM_000254	NP_000245	Q99707	METH_HUMAN	Homo sapiens 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR), mRNA.	633					nervous system development|xenobiotic metabolic process	cytosol	cobalamin binding|homocysteine S-methyltransferase activity|methionine synthase activity|protein binding|zinc ion binding			breast(4)|central_nervous_system(1)|cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(8)|lung(30)|ovary(1)|pancreas(1)|prostate(2)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	67	Ovarian(103;0.0634)|Breast(184;0.221)	all_cancers(173;2.79e-22)|all_epithelial(177;4.84e-14)|Breast(1374;0.00123)|Prostate(94;0.0181)|Lung SC(1967;0.0262)|Acute lymphoblastic leukemia(190;0.117)	OV - Ovarian serous cystadenocarcinoma(106;0.0106)	KIRC - Kidney renal clear cell carcinoma(1967;0.248)	Hydroxocobalamin(DB00200)|L-Methionine(DB00134)|Tetrahydrofolic acid(DB00116)	GCTCTGTGAAGATCTCATCTG	0.438000													14	46					0	0	1	0	0
WDR43	23160	broad.mit.edu	37	2	29158461	29158461	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr2:29158461G>A	uc002rmo.2	+	11	1544	c.1512G>A	c.(1510-1512)ccG>ccA	p.P504P		NM_015131	NP_055946	Q15061	WDR43_HUMAN	Homo sapiens WD repeat domain 43 (WDR43), mRNA.	504						nucleolus				breast(3)|endometrium(2)|kidney(1)|large_intestine(3)|lung(9)|ovary(1)|prostate(1)	20	Acute lymphoblastic leukemia(172;0.155)					CTATTATTCCGTTGTTACAAG	0.323000													12	31					0	0	1	0	0
BC080605	0	broad.mit.edu	37	9	68413639	68413639	+	RNA	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr9:68413639G>C	uc004aex.3	+	0		c.194G>C								Homo sapiens mRNA; cDNA DKFZp564N0763 (from clone DKFZp564N0763).																		TAACAGGCTGGAGGTGAGTGC	0.632000													3	23					0	0	1	0	0
WDR72	256764	broad.mit.edu	37	15	53889416	53889416	+	Missense_Mutation	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr15:53889416C>A	uc002acj.2	-	17	3050	c.3008G>T	c.(3007-3009)aGt>aTt	p.S1003I		NM_182758	NP_877435	Q3MJ13	WDR72_HUMAN	Homo sapiens WD repeat domain 72 (WDR72), mRNA.	1003										NS(1)|breast(1)|endometrium(4)|kidney(4)|large_intestine(18)|lung(29)|prostate(3)|skin(6)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	71				all cancers(107;0.0511)		CTTTCCCAAACTCTTCATGTG	0.388000													15	68					0	0	1	0	0
LOC399753	399753	broad.mit.edu	37	10	49219518	49219518	+	Silent	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:49219518C>T	uc001jgd.3	-	7	780	c.621G>A	c.(619-621)cgG>cgA	p.R207R						Homo sapiens uncharacterized LOC399753 (LOC399753), non-coding RNA.																		AGCGCATGGACCGCTTGCAAA	0.572000													78	468					0	0	1	0	0
AK302879	0	broad.mit.edu	37	15	76074504	76074504	+	Silent	SNP	C	C	T	rs146281026	by1000genomes	TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr15:76074504C>T	uc010umm.1	+	7	683	c.606C>T	c.(604-606)caC>caT	p.H202H	DNM1P35_uc021sqp.1_Intron|DQ582939_uc002bba.1_5'Flank					SubName: Full=cDNA FLJ59077, highly similar to Golgin subfamily A member 6;																		TGAACGCACACGTGACACAGG	0.572000													3	30					0	0	1	0	0
KCNJ18	100134444	broad.mit.edu	37	17	21319329	21319329	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:21319329G>A	uc021tss.1	+	2	1045	c.675G>A	c.(673-675)gaG>gaA	p.E225E	KCNJ18_uc002gyv.1_Silent_p.E225E|KCNJ18_uc021tst.1_Silent_p.E225E	NM_001194958	NP_001181887	B7U540	IRK18_HUMAN	Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 18 (KCNJ18), mRNA.	225						integral to membrane	inward rectifier potassium channel activity										ACATTGTGGAGGCCCATGTGC	0.642000													4	84					0	0	1	0	0
OR10J5	127385	broad.mit.edu	37	1	159505384	159505384	+	Silent	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:159505384C>T	uc010piw.2	-	0	414	c.414G>A	c.(412-414)aaG>aaA	p.K138K		NM_001004469	NP_001004469	Q8NHC4	O10J5_HUMAN	Homo sapiens olfactory receptor, family 10, subfamily J, member 5 (OR10J5), mRNA.	138					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			kidney(1)|large_intestine(4)|lung(9)|ovary(1)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)	22	all_hematologic(112;0.0429)					CACATAGTCCCTTGCTCATGA	0.502000													4	85					0	0	1	0	0
STAB2	55576	broad.mit.edu	37	12	104155079	104155079	+	Splice_Site	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr12:104155079C>T	uc001tjw.3	+	66	7435	c.7249_splice	c.e66-1	p.T2417_splice	STAB2_uc009zug.3_Splice_Site	NM_017564	NP_060034	Q8WWQ8	STAB2_HUMAN	Homo sapiens stabilin 2 (STAB2), mRNA.	2417	FAS1 7.				angiogenesis|cell adhesion|defense response to bacterium|receptor-mediated endocytosis	cytoplasm|external side of plasma membrane|integral to plasma membrane	Gram-negative bacterial cell surface binding|hyaluronic acid binding|low-density lipoprotein receptor activity|protein disulfide oxidoreductase activity|scavenger receptor activity	p.T2417M(1)		NS(4)|breast(7)|central_nervous_system(1)|cervix(1)|endometrium(15)|kidney(11)|large_intestine(26)|lung(77)|ovary(10)|pancreas(1)|prostate(5)|skin(14)|stomach(2)	174						TTTCCCTAGACGGAGACCAGG	0.512000													7	33					0	0	1	0	0
TMEM125	128218	broad.mit.edu	37	1	43738488	43738488	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:43738488G>A	uc021omm.1	+	0	95	c.95G>A	c.(94-96)cGg>cAg	p.R32Q	EBNA1BP2_uc001cio.3_5'Flank|TMEM125_uc021oml.1_Missense_Mutation_p.R32Q|TMEM125_uc001cir.3_Missense_Mutation_p.R32Q	NM_144626	NP_653227	Q96AQ2	TM125_HUMAN	Homo sapiens transmembrane protein 125 (TMEM125), mRNA.	32						integral to membrane				breast(1)|large_intestine(1)|lung(1)	3	Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0505)				CAGCAGCCGCGGCGCTCGGCG	0.711000													3	13					0	0	1	0	0
GABRA1	2554	broad.mit.edu	37	5	161318010	161318010	+	Silent	SNP	C	C	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr5:161318010C>G	uc010jiw.3	+	8	1278	c.810C>G	c.(808-810)gtC>gtG	p.V270V	GABRA1_uc010jix.3_Silent_p.V270V|GABRA1_uc010jiy.3_Silent_p.V270V|GABRA1_uc003lyx.4_Silent_p.V270V|GABRA1_uc010jiz.3_Silent_p.V270V|GABRA1_uc010jja.3_Silent_p.V270V|GABRA1_uc010jjb.3_Silent_p.V270V	NM_000806	NP_001121120	P14867	GBRA1_HUMAN	Homo sapiens gamma-aminobutyric acid (GABA) A receptor, alpha 1 (GABRA1), transcript variant 1, mRNA.	270					gamma-aminobutyric acid signaling pathway|synaptic transmission	cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	GABA-A receptor activity|chloride channel activity|extracellular ligand-gated ion channel activity			NS(1)|endometrium(2)|kidney(3)|large_intestine(4)|liver(1)|lung(22)|ovary(2)|pancreas(2)|prostate(1)|skin(3)|urinary_tract(1)	42	Renal(175;0.00259)	Medulloblastoma(196;0.0208)|all_neural(177;0.0672)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.228)	Alprazolam(DB00404)|Butabarbital(DB00237)|Butalbital(DB00241)|Butethal(DB01353)|Chlordiazepoxide(DB00475)|Clobazam(DB00349)|Clonazepam(DB01068)|Clorazepate(DB00628)|Desflurane(DB01189)|Diazepam(DB00829)|Enflurane(DB00228)|Ethanol(DB00898)|Ethchlorvynol(DB00189)|Etomidate(DB00292)|Flumazenil(DB01205)|Flurazepam(DB00690)|Halazepam(DB00801)|Halothane(DB01159)|Hexobarbital(DB01355)|Isoflurane(DB00753)|Lorazepam(DB00186)|Meprobamate(DB00371)|Metharbital(DB00463)|Methohexital(DB00474)|Methoxyflurane(DB01028)|Methylphenobarbital(DB00849)|Methyprylon(DB01107)|Midazolam(DB00683)|Nitrazepam(DB01595)|Oxazepam(DB00842)|Pentobarbital(DB00312)|Phenobarbital(DB01174)|Picrotoxin(DB00466)|Prazepam(DB01588)|Primidone(DB00794)|Progabide(DB00837)|Propofol(DB00818)|Quazepam(DB01589)|Secobarbital(DB00418)|Sevoflurane(DB01236)|Talbutal(DB00306)|Thiamylal(DB01154)|Thiopental(DB00599)|Topiramate(DB00273)|Zaleplon(DB00962)|Zolpidem(DB00425)	TCTCACAAGTCTCCTTCTGGC	0.408000													61	10					0	0	1	0	0
SSTR4	6754	broad.mit.edu	37	20	23016994	23016994	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr20:23016994G>A	uc002wsr.2	+	0	938	c.874G>A	c.(874-876)Gtc>Atc	p.V292I		NM_001052	NP_001043	P31391	SSR4_HUMAN	Homo sapiens somatostatin receptor 4 (SSTR4), mRNA.	292					G-protein signaling, coupled to cyclic nucleotide second messenger|negative regulation of cell proliferation	integral to plasma membrane	somatostatin receptor activity	p.T291T(2)		breast(1)|central_nervous_system(2)|endometrium(6)|kidney(1)|large_intestine(4)|lung(16)|ovary(1)|upper_aerodigestive_tract(1)	32	Colorectal(13;0.0518)|Lung NSC(19;0.0542)|all_lung(19;0.118)					TGATGCCACCGTCAACCACGT	0.567000													46	21					0	0	1	0	0
TTLL6	284076	broad.mit.edu	37	17	46847428	46847428	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:46847428G>A	uc021tzm.1	-	13	2107	c.2072C>T	c.(2071-2073)tCc>tTc	p.S691F	TTLL6_uc002iob.3_Missense_Mutation_p.S384F|TTLL6_uc010dbi.3_Intron|TTLL6_uc002ioc.3_Missense_Mutation_p.S444F|TTLL6_uc002iod.3_Intron	NM_001130918	NP_001124390	Q8N841	TTLL6_HUMAN	Homo sapiens tubulin tyrosine ligase-like family, member 6 (TTLL6), transcript variant 1, mRNA.	643						cilium|microtubule basal body	ATP binding|tubulin binding|tubulin-tyrosine ligase activity			endometrium(1)|large_intestine(5)|lung(9)|prostate(1)|skin(2)	18						TTGGGTGGTGGATTCTGGGGT	0.498000													11	88					0	0	1	0	0
FOXR2	139628	broad.mit.edu	37	X	55650343	55650343	+	Missense_Mutation	SNP	C	C	A	rs142979047	byFrequency	TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrX:55650343C>A	uc004duo.3	+	0	511	c.199C>A	c.(199-201)Cct>Act	p.P67T		NM_198451	NP_940853	Q6PJQ5	FOXR2_HUMAN	Homo sapiens forkhead box R2 (FOXR2), mRNA.	67					embryo development|organ development|pattern specification process|regulation of sequence-specific DNA binding transcription factor activity|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding			biliary_tract(1)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(1)|liver(1)|lung(8)|prostate(1)|skin(1)|urinary_tract(1)	19						GAGACCCAGTCCTGATGGAGA	0.552000													25	36					0	0	1	0	0
ZNF384	171017	broad.mit.edu	37	12	6787485	6787485	+	Missense_Mutation	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr12:6787485G>C	uc010sfh.2	-	5	764	c.494C>G	c.(493-495)tCc>tGc	p.S165C	ZNF384_uc001qqa.3_Missense_Mutation_p.S165C|ZNF384_uc001qqd.3_Missense_Mutation_p.S110C|ZNF384_uc009zew.1_Missense_Mutation_p.S20C	NM_001135734	NP_001129206	Q8TF68	ZN384_HUMAN	Homo sapiens zinc finger protein 384 (ZNF384), transcript variant 7, mRNA.	165					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding		EWSR1/ZNF384(4)	breast(3)|central_nervous_system(3)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(1)|lung(6)|prostate(1)|urinary_tract(1)	18						TACCTTCTTGGAGAGGTCAGG	0.607000			T	"""EWSR1, TAF15 """	ALL								24	20					0	0	1	0	0
FAM86EP	348926	broad.mit.edu	37	4	3952901	3952901	+	RNA	SNP	A	A	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr4:3952901A>T	uc011bvu.2	-	2		c.207T>A			FAM86EP_uc003ghn.3_Intron					Homo sapiens family with sequence similarity 86, member E, pseudogene (FAM86EP), non-coding RNA.																		CACCGGGCATACTTGACTGAC	0.552000													4	53					0	0	1	0	0
MATR3	9782	broad.mit.edu	37	5	138643467	138643467	+	Missense_Mutation	SNP	C	C	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr5:138643467C>G	uc003ldw.3	+	2	766	c.363C>G	c.(361-363)gaC>gaG	p.D121E	MATR3_uc003lds.3_Missense_Mutation_p.D121E|MATR3_uc003ldt.3_Intron|MATR3_uc003ldu.3_Missense_Mutation_p.D121E|MATR3_uc010jfb.3_Missense_Mutation_p.D121E|MATR3_uc003ldx.3_Missense_Mutation_p.D121E|MATR3_uc003ldy.3_Intron|MATR3_uc003ldz.3_Missense_Mutation_p.D121E|MATR3_uc011czb.2_Intron	NM_018834	NP_954659	P43243	MATR3_HUMAN	Homo sapiens matrin 3 (MATR3), transcript variant 2, mRNA.	121						nuclear inner membrane|nuclear matrix	RNA binding|nucleotide binding|protein binding|structural molecule activity|zinc ion binding			breast(2)|endometrium(3)|kidney(4)|large_intestine(6)|lung(9)|ovary(2)|prostate(1)|skin(1)|urinary_tract(1)	29			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00325)			CTGCTAGAGACTTAGATGAAC	0.463000													9	52					0	0	1	0	0
UGDH	7358	broad.mit.edu	37	4	39506922	39506922	+	Missense_Mutation	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr4:39506922G>C	uc003guk.2	-	8	1429	c.1106C>G	c.(1105-1107)cCa>cGa	p.P369R	UGDH_uc011byp.2_Missense_Mutation_p.P272R|UGDH_uc003gul.2_Missense_Mutation_p.P302R	NM_003359	NP_001171630	O60701	UGDH_HUMAN	Homo sapiens UDP-glucose 6-dehydrogenase (UGDH), transcript variant 1, mRNA.	369					UDP-glucose metabolic process|UDP-glucuronate biosynthetic process|glycosaminoglycan biosynthetic process|xenobiotic metabolic process	cytosol	NAD binding|UDP-glucose 6-dehydrogenase activity|electron carrier activity			breast(1)|central_nervous_system(1)|cervix(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(6)|lung(10)|ovary(3)|skin(1)|urinary_tract(2)	27					NADH(DB00157)	AGGTACTTTTGGATCATATAT	0.348000													11	37					0	0	1	0	0
SYT15	83849	broad.mit.edu	37	10	46964009	46964009	+	Silent	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:46964009G>C	uc001jea.3	-	6	1107	c.954C>G	c.(952-954)gtC>gtG	p.V318V	SYT15_uc001jdz.2_Silent_p.V318V|SYT15_uc001jeb.3_Silent_p.V196V|SYT15_uc010qfp.1_Non-coding_Transcript	NM_031912	NP_114118	Q9BQS2	SYT15_HUMAN	Homo sapiens synaptotagmin XV (SYT15), transcript variant a, mRNA.	318	C2 2.					integral to membrane|plasma membrane				cervix(1)|endometrium(5)|kidney(2)|lung(5)	13						GAGACACTTTGACAAACACAC	0.562000													19	152					0	0	1	0	0
PROKR2	128674	broad.mit.edu	37	20	5282948	5282948	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr20:5282948C>T	uc010zqw.2	-	1	901	c.893G>A	c.(892-894)cGt>cAt	p.R298H	PROKR2_uc010zqx.2_Missense_Mutation_p.R298H|PROKR2_uc010zqy.2_Missense_Mutation_p.R298H	NM_144773	NP_658986	Q8NFJ6	PKR2_HUMAN	Homo sapiens prokineticin receptor 2 (PROKR2), mRNA.	298						integral to membrane|plasma membrane	neuropeptide Y receptor activity	p.R298C(2)		autonomic_ganglia(1)|breast(3)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(4)|liver(3)|lung(22)|ovary(5)|pancreas(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(4)	53						GAAGAAGTCACGAACGATGGT	0.562000										HNSCC(71;0.22)			42	22					0	0	1	0	0
AKR1E2	83592	broad.mit.edu	37	10	4877922	4877922	+	Missense_Mutation	SNP	A	A	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:4877922A>T	uc001ihi.3	+	3	495	c.380A>T	c.(379-381)cAt>cTt	p.H127L	AKR1E2_uc010qam.1_Missense_Mutation_p.H88L|AKR1E2_uc001ihh.1_Missense_Mutation_p.H127L|AKR1E2_uc001ihj.3_Non-coding_Transcript|AKR1E2_uc001ihk.3_Missense_Mutation_p.H127L|AKR1E2_uc009xhw.3_Missense_Mutation_p.H127L	NM_001040177	NP_001035267	Q96JD6	AKCL2_HUMAN	Homo sapiens aldo-keto reductase family 1, member E2 (AKR1E2), mRNA.	127						cytoplasm	1,5-anhydro-D-fructose reductase activity			NS(1)|endometrium(2)|kidney(2)|large_intestine(1)|lung(9)	15						TGCCTCTCACATCCTCGAGTG	0.512000													4	55					0	0	1	0	0
USP42	84132	broad.mit.edu	37	7	6175578	6175578	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr7:6175578G>A	uc011jwo.1	+	3	672	c.549G>A	c.(547-549)atG>atA	p.M183I	USP42_uc011jwn.1_Missense_Mutation_p.M28I|USP42_uc010kth.1_Missense_Mutation_p.M116I|USP42_uc011jwp.2_Missense_Mutation_p.M183I|USP42_uc011jwq.2_5'UTR|USP42_uc011jwr.1_Missense_Mutation_p.M28I	NM_032172	NP_115548	Q9H9J4	UBP42_HUMAN	Homo sapiens ubiquitin specific peptidase 42 (USP42), mRNA.	183					cell differentiation|protein deubiquitination|spermatogenesis|ubiquitin-dependent protein catabolic process		cysteine-type peptidase activity|ubiquitin thiolesterase activity			breast(1)|central_nervous_system(1)|endometrium(5)|kidney(4)|large_intestine(2)|lung(14)|ovary(2)|pancreas(1)|prostate(1)|skin(3)|urinary_tract(1)	35		Ovarian(82;0.0423)		UCEC - Uterine corpus endometrioid carcinoma (126;0.108)|OV - Ovarian serous cystadenocarcinoma(56;5.77e-14)		TCAATGAGATGCGGCGTAAGT	0.348000													8	12					0	0	1	0	0
CCR7	1236	broad.mit.edu	37	17	38711153	38711153	+	Silent	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:38711153G>A	uc002huw.3	-	2	1053	c.978C>T	c.(976-978)taC>taT	p.Y326Y		NM_001838	NP_001829	P32248	CCR7_HUMAN	Homo sapiens chemokine (C-C motif) receptor 7 (CCR7), mRNA.	326					T cell costimulation|cell maturation|immunological synapse formation|inflammatory response|interleukin-12 secretion|lymphocyte migration into lymph node|positive regulation of dendritic cell antigen processing and presentation|positive regulation of glycoprotein biosynthetic process|positive regulation of humoral immune response|positive regulation of hypersensitivity|positive regulation of interleukin-12 production|positive regulation of neutrophil chemotaxis|regulation of interferon-gamma production|regulation of interleukin-1 beta secretion	integral to membrane|intracellular	C-C chemokine receptor activity|chemokine (C-C motif) ligand 19 binding|chemokine (C-C motif) ligand 21 binding			breast(1)|large_intestine(4)|lung(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	8		Breast(137;0.000496)				CGATGAAGGCGTACAAGAAAG	0.587000													14	45					0	0	1	0	0
PTPRD	5789	broad.mit.edu	37	9	8331734	8331734	+	Silent	SNP	G	G	A	rs143526425	byFrequency	TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr9:8331734G>A	uc003zkk.3	-	43	6125	c.5382C>T	c.(5380-5382)gaC>gaT	p.D1794D	PTPRD_uc003zkp.3_Silent_p.D1388D|PTPRD_uc003zkq.3_Silent_p.D1387D|PTPRD_uc003zkr.3_Silent_p.D1378D|PTPRD_uc003zks.3_Silent_p.D1387D|PTPRD_uc022bdj.1_Silent_p.D1384D	NM_002839	NP_002830	P23468	PTPRD_HUMAN	Homo sapiens protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 1, mRNA.	1794	Tyrosine-protein phosphatase 2.				transmembrane receptor protein tyrosine phosphatase signaling pathway	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity			NS(1)|breast(7)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(22)|liver(1)|lung(83)|ovary(4)|pancreas(1)|prostate(7)|skin(19)|stomach(3)|upper_aerodigestive_tract(5)|urinary_tract(1)	168		all_cancers(3;3.38e-95)|all_epithelial(3;2.84e-91)|all_lung(3;7.3e-56)|Lung NSC(3;1.82e-52)|Renal(3;3.42e-19)|all_hematologic(3;0.000134)|all_neural(3;0.00409)|Acute lymphoblastic leukemia(23;0.0069)|Melanoma(3;0.0121)|Myeloproliferative disorder(4;0.0122)|Medulloblastoma(3;0.0144)|Lung SC(3;0.0301)|Ovarian(56;0.0694)|Hepatocellular(3;0.0824)		all cancers(1;3.38e-12)|Epithelial(1;2.12e-09)|STAD - Stomach adenocarcinoma(1;1.29e-07)|KIRC - Kidney renal clear cell carcinoma(3;5.49e-07)|Kidney(3;6.36e-07)|GBM - Glioblastoma multiforme(50;9.05e-05)|Lung(1;0.000189)|BRCA - Breast invasive adenocarcinoma(1;0.00178)|LUSC - Lung squamous cell carcinoma(1;0.0115)|LUAD - Lung adenocarcinoma(58;0.119)		GGGACTGGCCGTCCTTTAGAA	0.512000										TSP Lung(15;0.13)			13	32					0	0	1	0	0
BAGE1	0	broad.mit.edu	37	GL000237.1	403	403	+	RNA	SNP	T	T	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrGL000237.1:403T>C	uc011mgu.1	-	1		c.815A>G								Homo sapiens B melanoma antigen variant f (BAGE1) mRNA, complete cds, alternatively spliced.																		ggggatcccatgacaccaaaa	0.473000													3	11					0	0	1	0	0
TEX2	55852	broad.mit.edu	37	17	62272447	62272447	+	Missense_Mutation	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr17:62272447C>A	uc002jed.3	-	2	1804	c.1653G>T	c.(1651-1653)atG>atT	p.M551I	TEX2_uc002jec.3_Missense_Mutation_p.M551I|TEX2_uc002jee.3_Missense_Mutation_p.M551I	NM_018469	NP_060939	Q8IWB9	TEX2_HUMAN	Homo sapiens testis expressed 2 (TEX2), mRNA.	551					signal transduction|sphingolipid metabolic process	integral to membrane				breast(3)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(2)|lung(15)|ovary(1)|pancreas(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	41			BRCA - Breast invasive adenocarcinoma(8;1.33e-10)	READ - Rectum adenocarcinoma(1115;0.0689)		AAATCTCATTCATCCATCCCT	0.383000													6	56					0	0	1	0	0
MAG	4099	broad.mit.edu	37	19	35791110	35791110	+	Missense_Mutation	SNP	G	G	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr19:35791110G>T	uc002nyy.2	+	5	971	c.773G>T	c.(772-774)aGc>aTc	p.S258I	MAG_uc002nyx.2_Missense_Mutation_p.S258I|MAG_uc010eds.2_Missense_Mutation_p.S233I|MAG_uc002nyz.2_Missense_Mutation_p.S258I	NM_002361	NP_001186145	P20916	MAG_HUMAN	Homo sapiens myelin associated glycoprotein (MAG), transcript variant 1, mRNA.	258	Ig-like C2-type 2.				blood coagulation|cell adhesion|leukocyte migration|negative regulation of axonogenesis|nerve growth factor receptor signaling pathway	integral to membrane|plasma membrane	sugar binding			NS(1)|breast(4)|central_nervous_system(1)|endometrium(3)|large_intestine(10)|lung(11)|skin(2)|upper_aerodigestive_tract(2)	34	all_lung(56;2.37e-08)|Lung NSC(56;3.66e-08)|Esophageal squamous(110;0.162)	Renal(1328;0.242)	Epithelial(14;3.14e-19)|OV - Ovarian serous cystadenocarcinoma(14;1.5e-18)|all cancers(14;1.5e-16)|LUSC - Lung squamous cell carcinoma(66;0.0417)			TCCCACGTGAGCCTGCTCTGT	0.677000													7	10					0	0	1	0	0
LOC220729	220729	broad.mit.edu	37	3	197348646	197348646	+	RNA	SNP	T	T	C	rs138265355	by1000genomes	TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr3:197348646T>C	uc011bug.2	-	3		c.445A>G			LOC220729_uc003fxy.3_Non-coding_Transcript|LOC220729_uc010iao.2_Intron					Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) pseudogene (LOC220729), non-coding RNA.																		TGGGCCTGCCTGCCCTTTCCA	0.532000													6	91					0	0	1	0	0
PPP2R2D	55844	broad.mit.edu	37	10	133758848	133758848	+	Silent	SNP	C	C	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:133758848C>A	uc001lks.3	+	4	607	c.606C>A	c.(604-606)atC>atA	p.I202I	PPP2R2D_uc001lkr.3_Silent_p.I8I|PPP2R2D_uc001lkt.3_Silent_p.I8I|PPP2R2D_uc009yay.3_Silent_p.I70I	NM_018461	NP_060931	Q66LE6	2ABD_HUMAN	Homo sapiens protein phosphatase 2, regulatory subunit B, delta (PPP2R2D), transcript variant 1, mRNA.	235					cell division|exit from mitosis|mitosis|signal transduction	cytoplasm|protein phosphatase type 2A complex	protein phosphatase type 2A regulator activity			endometrium(3)|large_intestine(3)|liver(1)|lung(4)|skin(1)|upper_aerodigestive_tract(1)	13		all_cancers(35;2.16e-12)|all_epithelial(44;2.77e-09)|Lung NSC(174;0.00237)|all_lung(145;0.00354)|Colorectal(31;0.0124)|Breast(234;0.023)|all_neural(114;0.0299)|Melanoma(40;0.123)|Glioma(114;0.203)		OV - Ovarian serous cystadenocarcinoma(35;7.86e-05)|Epithelial(32;8.82e-05)|all cancers(32;0.000106)|BRCA - Breast invasive adenocarcinoma(275;0.21)		CCGAAGTCATCACTGCAGCCG	0.562000													15	97					0	0	1	0	0
FCGBP	8857	broad.mit.edu	37	19	40374023	40374023	+	Missense_Mutation	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr19:40374023C>T	uc002omp.4	-	25	12063	c.12055G>A	c.(12055-12057)Gtg>Atg	p.V4019M		NM_003890	NP_003881	Q9Y6R7	FCGBP_HUMAN	Homo sapiens Fc fragment of IgG binding protein (FCGBP), mRNA.	4019	Cys-rich.					extracellular region	protein binding			NS(3)|autonomic_ganglia(1)|breast(7)|central_nervous_system(5)|endometrium(13)|kidney(9)|large_intestine(27)|lung(49)|ovary(8)|pancreas(3)|prostate(13)|skin(9)|stomach(9)|upper_aerodigestive_tract(6)|urinary_tract(3)	165	all_cancers(60;6.03e-06)|all_lung(34;5.58e-08)|Lung NSC(34;6.62e-08)|Ovarian(47;0.06)		Epithelial(26;6.25e-23)|all cancers(26;1.13e-20)			TGGCACACCACGACTTTACCC	0.642000													3	18					0	0	1	0	0
ZNF167	55888	broad.mit.edu	37	3	44611529	44611529	+	Silent	SNP	A	A	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr3:44611529A>T	uc003cnj.3	+	5	1343	c.927A>T	c.(925-927)gcA>gcT	p.A309A	ZNF167_uc003cnk.3_Intron|ZNF167_uc003cnh.3_Non-coding_Transcript|ZNF167_uc010hin.3_Silent_p.A309A|ZNF167_uc003cni.3_Intron|ZNF167_uc010hio.3_Silent_p.A158A	NM_018651	NP_061121	Q9P0L1	ZN167_HUMAN	Homo sapiens zinc finger protein 167 (ZNF167), transcript variant 1, mRNA.	309					viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|endometrium(1)|kidney(3)|large_intestine(12)|lung(4)|ovary(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	29				KIRC - Kidney renal clear cell carcinoma(197;0.0486)|Kidney(197;0.0609)		CTGGGGCAGCAGAGACTGGAG	0.438000													28	116					0	0	1	0	0
CDH9	1007	broad.mit.edu	37	5	26886102	26886102	+	Missense_Mutation	SNP	G	G	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr5:26886102G>C	uc003jgs.1	-	9	1772	c.1603C>G	c.(1603-1605)Ccg>Gcg	p.P535A	CDH9_uc011cnv.1_Missense_Mutation_p.P128A	NM_016279	NP_057363	Q9ULB4	CADH9_HUMAN	Homo sapiens cadherin 9, type 2 (T1-cadherin) (CDH9), mRNA.	535	Cadherin 5.				adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding	p.P535T(2)|p.P535L(1)		breast(6)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(25)|lung(80)|ovary(5)|prostate(4)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(1)	137						GTGAAATTCGGATTGAGAGTA	0.318000													4	94					0	0	1	0	0
FZD1	8321	broad.mit.edu	37	7	90895680	90895680	+	Silent	SNP	C	C	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr7:90895680C>G	uc003ula.3	+	0	1898	c.1485C>G	c.(1483-1485)ctC>ctG	p.L495L		NM_003505	NP_003496	Q9UP38	FZD1_HUMAN	Homo sapiens frizzled family receptor 1 (FZD1), mRNA.	495					G-protein signaling, coupled to cGMP nucleotide second messenger|Wnt receptor signaling pathway, calcium modulating pathway|autocrine signaling|axonogenesis|brain development|canonical Wnt receptor signaling pathway involved in mesenchymal stem cell differentiation|canonical Wnt receptor signaling pathway involved in osteoblast differentiation|embryo development|epithelial cell differentiation|gonad development|lung alveolus development|negative regulation of BMP signaling pathway|negative regulation of canonical Wnt receptor signaling pathway|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription, DNA-dependent|response to drug|vasculature development	apical part of cell|cell surface|cytoplasm|integral to membrane|neuron projection membrane	G-protein coupled receptor activity|PDZ domain binding|Wnt receptor activity|Wnt-protein binding|receptor binding			breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(4)|liver(1)|lung(7)|ovary(1)|prostate(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	24	all_cancers(62;3.1e-10)|all_epithelial(64;1.66e-08)|Breast(17;0.000635)|Lung NSC(181;0.153)|all_lung(186;0.154)|all_hematologic(106;0.215)		STAD - Stomach adenocarcinoma(171;0.0134)			TGGCGCCCCTCTTCGTGTACC	0.622000													74	100					0	0	1	0	0
TAS2R1	50834	broad.mit.edu	37	5	9630016	9630016	+	Silent	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr5:9630016C>T	uc003jem.1	-	0	448	c.129G>A	c.(127-129)ccG>ccA	p.P43P		NM_019599	NP_062545	Q9NYW7	TA2R1_HUMAN	Homo sapiens taste receptor, type 2, member 1 (TAS2R1), mRNA.	43					chemosensory behavior|sensory perception of taste	integral to membrane	taste receptor activity	p.A42V(1)		breast(5)|central_nervous_system(1)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(19)|ovary(3)|prostate(1)|skin(1)|stomach(1)	39						GGAGATCCAGCGGAGCCATTT	0.378000													8	72					0	0	1	0	0
SCN8A	6334	broad.mit.edu	37	12	52139791	52139791	+	Missense_Mutation	SNP	G	G	A			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr12:52139791G>A	uc001ryw.3	+	12	2281	c.2103G>A	c.(2101-2103)atG>atA	p.M701I	SCN8A_uc010snl.2_Missense_Mutation_p.M701I|SCN8A_uc001ryx.1_Missense_Mutation_p.M577I|SCN8A_uc001ryz.1_Missense_Mutation_p.M577I|SCN8A_uc001ryy.2_Missense_Mutation_p.M566I	NM_014191	NP_055006	Q9UQD0	SCN8A_HUMAN	Homo sapiens sodium channel, voltage gated, type VIII, alpha subunit (SCN8A), transcript variant 1, mRNA.	701					axon guidance|myelination|peripheral nervous system development	cytoplasmic membrane-bounded vesicle|node of Ranvier	ATP binding|voltage-gated sodium channel activity			breast(2)|central_nervous_system(1)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(7)|lung(19)|ovary(8)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	55				BRCA - Breast invasive adenocarcinoma(357;0.181)	Lamotrigine(DB00555)	ACAGTATAATGAGTGTTGTTA	0.403000													22	19					0	0	1	0	0
NFATC2	4773	broad.mit.edu	37	20	50139907	50139907	+	Silent	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr20:50139907C>T	uc002xwd.3	-	1	1093	c.873G>A	c.(871-873)ccG>ccA	p.P291P	NFATC2_uc002xwc.3_Silent_p.P291P|NFATC2_uc010zyv.2_Silent_p.P72P|NFATC2_uc010zyw.2_Silent_p.P72P|NFATC2_uc002xwe.3_Silent_p.P271P|NFATC2_uc010zyx.2_Silent_p.P271P|NFATC2_uc010zyy.2_Silent_p.P72P|NFATC2_uc010zyz.2_Silent_p.P72P	NM_173091	NP_775114	Q13469	NFAC2_HUMAN	Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 2, mRNA.	291					B cell receptor signaling pathway|positive regulation of B cell proliferation|response to DNA damage stimulus|response to drug	actin cytoskeleton|nucleus|plasma membrane	protein binding|sequence-specific DNA binding transcription factor activity	p.P291Q(1)	EWSR1/NFATC2(9)	breast(2)|endometrium(7)|kidney(1)|large_intestine(7)|lung(25)|ovary(2)|prostate(2)|skin(5)|stomach(1)|urinary_tract(1)	53	Hepatocellular(150;0.248)					GGTACCCAGCCGGGGAGCCGT	0.697000													16	17					0	0	1	0	0
DYSF	8291	broad.mit.edu	37	2	71780304	71780304	+	Missense_Mutation	SNP	G	G	C	rs150417363		TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr2:71780304G>C	uc010fen.3	+	19	2111	c.1970G>C	c.(1969-1971)cGt>cCt	p.R657P	DYSF_uc010fei.3_Missense_Mutation_p.R656P|DYSF_uc010feh.3_Missense_Mutation_p.R625P|DYSF_uc002sig.4_Missense_Mutation_p.R625P|DYSF_uc010yqx.2_Non-coding_Transcript|DYSF_uc010feg.3_Missense_Mutation_p.R670P|DYSF_uc010fee.3_Missense_Mutation_p.R639P|DYSF_uc010fef.3_Missense_Mutation_p.R656P|DYSF_uc002sie.3_Missense_Mutation_p.R639P|DYSF_uc010feo.3_Missense_Mutation_p.R671P|DYSF_uc010fej.3_Missense_Mutation_p.R626P|DYSF_uc010fel.3_Missense_Mutation_p.R626P|DYSF_uc010fem.3_Missense_Mutation_p.R640P|DYSF_uc002sif.3_Missense_Mutation_p.R640P|DYSF_uc010fek.3_Missense_Mutation_p.R657P	NM_001130987	NP_001124459	O75923	DYSF_HUMAN	Homo sapiens dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) (DYSF), transcript variant 1, mRNA.	639						cytoplasmic vesicle membrane|integral to membrane|sarcolemma	calcium-dependent phospholipid binding			autonomic_ganglia(2)|breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(22)|lung(57)|ovary(3)|pancreas(1)|prostate(2)|skin(6)|upper_aerodigestive_tract(3)|urinary_tract(2)	111						CAGTACAGCCGTGCAGTCTTT	0.582000													10	113					0	0	1	0	0
CNTN3	5067	broad.mit.edu	37	3	74411041	74411041	+	Splice_Site	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr3:74411041C>T	uc003dpm.1	-	10	1444	c.1364_splice	c.e10+1	p.R455_splice		NM_020872	NP_065923	Q9P232	CNTN3_HUMAN	Homo sapiens contactin 3 (plasmacytoma associated) (CNTN3), mRNA.	455	Ig-like C2-type 5.				cell adhesion	anchored to membrane|plasma membrane	protein binding			NS(2)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(14)|lung(39)|ovary(1)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	83		Lung NSC(201;0.138)|Lung SC(41;0.21)		Epithelial(33;0.00212)|BRCA - Breast invasive adenocarcinoma(55;0.00258)|LUSC - Lung squamous cell carcinoma(21;0.00461)|Lung(16;0.01)		ATCAAAATACCTTTCATGCTC	0.448000													27	21					0	0	1	0	0
NCOA6	23054	broad.mit.edu	37	20	33345744	33345744	+	Silent	SNP	C	C	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr20:33345744C>T	uc002xav.3	-	7	3378	c.807G>A	c.(805-807)caG>caA	p.Q269Q	NCOA6_uc002xaw.3_Silent_p.Q269Q|NCOA6_uc021wcd.1_Silent_p.Q269Q|NCOA6_uc021wce.1_Silent_p.Q269Q|NCOA6_uc021wcf.1_Silent_p.Q269Q|NCOA6_uc010gew.1_Silent_p.Q226Q	NM_014071	NP_054790	Q14686	NCOA6_HUMAN	Homo sapiens nuclear receptor coactivator 6 (NCOA6), transcript variant 1, mRNA.	269	CREBBP-binding region.|Gln-rich.|NCOA1-binding region.|TBP/GTF2A-binding region.				DNA recombination|DNA repair|DNA replication|brain development|cellular lipid metabolic process|estrogen receptor signaling pathway|glucocorticoid receptor signaling pathway|heart development|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|response to hormone stimulus|transcription initiation from RNA polymerase II promoter	transcription factor complex	chromatin binding|enzyme binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoid X receptor binding|thyroid hormone receptor binding	p.Q269Q(29)		NS(2)|breast(6)|central_nervous_system(3)|cervix(1)|endometrium(9)|kidney(8)|large_intestine(16)|lung(37)|ovary(4)|prostate(5)|skin(13)|upper_aerodigestive_tract(2)|urinary_tract(1)	107						gctgctgctgctgttgttgtt	0.537000													4	94					0	0	1	0	0
AK021933	0	broad.mit.edu	37	GL000195.1	31176	31176	+	RNA	SNP	C	C	G			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chrGL000195.1:31176C>G	uc003woi.3	-	0		c.805G>C								Homo sapiens cDNA FLJ11871 fis, clone HEMBA1007052.																		GATTAGCGCACTCTCCCTGAT	0.542000													4	17					0	0	1	0	0
MKI67	4288	broad.mit.edu	37	10	129905829	129905829	+	Silent	SNP	T	T	C			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr10:129905829T>C	uc001lke.3	-	12	4470	c.4275A>G	c.(4273-4275)ggA>ggG	p.G1425G	MKI67_uc001lkf.3_Silent_p.G1065G|MKI67_uc009yav.1_Silent_p.G1000G|MKI67_uc009yaw.1_Silent_p.G575G	NM_002417	NP_002408	P46013	KI67_HUMAN	Homo sapiens antigen identified by monoclonal antibody Ki-67 (MKI67), transcript variant 1, mRNA.	1425	16 X 122 AA approximate repeats.				cell proliferation	nucleolus	ATP binding|protein C-terminus binding			NS(2)|autonomic_ganglia(1)|breast(2)|central_nervous_system(2)|cervix(2)|endometrium(14)|haematopoietic_and_lymphoid_tissue(5)|kidney(7)|large_intestine(30)|lung(64)|ovary(4)|pancreas(1)|prostate(4)|skin(2)|soft_tissue(1)|stomach(10)|upper_aerodigestive_tract(4)|urinary_tract(4)	159		all_epithelial(44;2.12e-05)|all_lung(145;0.00679)|Lung NSC(174;0.00998)|all_neural(114;0.0936)|Colorectal(57;0.14)|Breast(234;0.166)|Melanoma(40;0.203)				TATCCTCACCTCCTGGTACTT	0.483000													5	241					0	0	1	0	0
RAB42	115273	broad.mit.edu	37	1	28920318	28920318	+	Missense_Mutation	SNP	A	A	T			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:28920318A>T	uc001bqv.3	+	1	363	c.346A>T	c.(346-348)Act>Tct	p.T116S	RAB42_uc001bqu.3_Missense_Mutation_p.T3S|RAB42_uc021okd.1_Missense_Mutation_p.T3S	NM_001193532	NP_001180461	Q8N4Z0	RAB42_HUMAN	Homo sapiens RAB42, member RAS oncogene family (RAB42), transcript variant 1, mRNA.	3					small GTPase mediated signal transduction	membrane	GTP binding			breast(1)|endometrium(1)|large_intestine(1)|lung(2)	5		Colorectal(325;0.000147)|Renal(390;0.00357)|Lung NSC(340;0.00618)|all_lung(284;0.00909)|Breast(348;0.0249)|Myeloproliferative disorder(586;0.0393)|all_neural(195;0.0577)|Ovarian(437;0.127)|Medulloblastoma(700;0.151)		Colorectal(126;2.96e-08)|COAD - Colon adenocarcinoma(152;1.7e-06)|STAD - Stomach adenocarcinoma(196;0.00298)|KIRC - Kidney renal clear cell carcinoma(1967;0.00948)|BRCA - Breast invasive adenocarcinoma(304;0.0213)|READ - Rectum adenocarcinoma(331;0.0649)		GGTCATGGCCACTCAGGGCCC	0.577000													7	6					0	0	1	0	0
CD34	947	broad.mit.edu	37	1	208070903	208070903	+	Frame_Shift_Del	DEL	A	A	-			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr1:208070903delA	uc001hgw.1	-	3	790	c.532delT	c.(532-534)tcafs	p.S178fs	CD34_uc001hgx.1_Frame_Shift_Del_p.S178fs|CD34_uc010psj.1_Frame_Shift_Del_p.S43fs	NM_001025109	NP_001020280	P28906	CD34_HUMAN	Homo sapiens CD34 molecule (CD34), transcript variant 1, mRNA.	178					cell-cell adhesion|leukocyte migration|regulation of immune response	integral to membrane	carbohydrate binding			kidney(2)|large_intestine(2)|lung(8)|ovary(1)	13						CTGATGCCTGAACATTTGATT	0.418													2	4	---	---	---	---					
SRP72	6731	broad.mit.edu	37	4	57333819	57333820	+	Frame_Shift_Ins	INS	-	-	G	rs17524437	by1000genomes	TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr4:57333819_57333820insG	uc003hbv.3	+	0	58_59	c.18_19insG	c.(16-21)agcgggfs	p.S6fs	SRP72_uc010ihe.3_Frame_Shift_Ins_p.S6fs	NM_006947	NP_008878	O76094	SRP72_HUMAN	Homo sapiens signal recognition particle 72kDa (SRP72), mRNA.	6					SRP-dependent cotranslational protein targeting to membrane|response to drug	cytosol|nucleolus|plasma membrane|signal recognition particle, endoplasmic reticulum targeting	7S RNA binding|signal recognition particle binding			breast(2)|endometrium(4)|kidney(1)|large_intestine(4)|liver(2)|lung(7)|ovary(2)	22	Glioma(25;0.08)|all_neural(26;0.101)					GCGGCGGCAGCGGGGGGGTGTC	0.639													10	21	---	---	---	---					
ZNF252P-AS1	286103	broad.mit.edu	37	8	146228843	146228843	+	Frame_Shift_Del	DEL	G	G	-			TCGA-N8-A4PQ-01A-11D-A28R-08	TCGA-N8-A4PQ-10A-01D-A28U-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a3eaab79-ec94-43ea-bdeb-8e2b2a0ef27f	cab88f55-36e4-4645-a74e-6e3a2911e9c8	g.chr8:146228843delG	uc003zfb.4	+	0	647	c.471delG	c.(469-471)gcgfs	p.A157fs	ZNF252P_uc003zew.4_5'Flank|ZNF252P_uc011llo.2_5'Flank					Homo sapiens chromosome 8 open reading frame 77 (C8orf77), non-coding RNA.																		GGCGGCGGGCGGGGGTGAAGC	0.652													2	4	---	---	---	---					
