Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PHF20L1	51105	broad.mit.edu	37	8	133829702	133829702	+	Missense_Mutation	SNP	T	T	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr8:133829702T>G	uc003ytt.3	+	11	1816	c.1491T>G	c.(1489-1491)tgT>tgG	p.C497W	PHF20L1_uc003yts.3_Missense_Mutation_p.C497W|PHF20L1_uc011lja.2_Missense_Mutation_p.C471W|PHF20L1_uc003ytu.1_Non-coding_Transcript	NM_016018	NP_057102	A8MW92	P20L1_HUMAN	Homo sapiens PHD finger protein 20-like 1 (PHF20L1), transcript variant 1, mRNA.	497							nucleic acid binding|zinc ion binding			breast(1)|endometrium(1)|large_intestine(1)|lung(10)|ovary(2)	15	all_neural(3;2.72e-06)|Medulloblastoma(3;7.08e-05)|Ovarian(258;0.00438)|Esophageal squamous(12;0.00507)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;4.46e-05)			GTAATGAATGTCCCAGGGCAG	0.478000													7	51					0	0	1	0	0
HCP5	10866	broad.mit.edu	37	6	31431638	31431638	+	RNA	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr6:31431638C>T	uc003ntl.3	+	1		c.591C>T			HCP5_uc021yup.1_Non-coding_Transcript			Q6MZN7	HCP5_HUMAN	Homo sapiens HLA complex P5 (non-protein coding) (HCP5), non-coding RNA.						defense response					urinary_tract(1)	1						tccctgggttccacacgaact	0.567000													21	30					0	0	1	0	0
MYO1A	4640	broad.mit.edu	37	12	57440666	57440666	+	Silent	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr12:57440666G>A	uc001smw.4	-	6	762	c.522C>T	c.(520-522)ctC>ctT	p.L174L	MYO1A_uc010sqz.2_Silent_p.L12L|MYO1A_uc009zpd.3_Silent_p.L174L	NM_005379	NP_005370	Q9UBC5	MYO1A_HUMAN	Homo sapiens myosin IA (MYO1A), transcript variant 2, mRNA.	174	Myosin head-like.				sensory perception of sound|vesicle localization	brush border|cortical actin cytoskeleton|filamentous actin|lateral plasma membrane|microvillus|myosin complex	ATP binding|actin binding|calmodulin binding|motor activity			breast(1)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(12)|lung(17)|ovary(2)|skin(7)|urinary_tract(3)	50						TGACACCACCGAGGGGGGATC	0.498000													11	124					0	0	1	0	0
LAMP2	3920	broad.mit.edu	37	X	119581842	119581842	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chrX:119581842G>A	uc004ess.4	-	4	775	c.595C>T	c.(595-597)Ccc>Tcc	p.P199S	LAMP2_uc004est.4_Missense_Mutation_p.P199S|LAMP2_uc011mtz.2_Missense_Mutation_p.P88S|LAMP2_uc011mua.1_Missense_Mutation_p.P152S|LAMP2_uc010nqp.1_Missense_Mutation_p.P199S	NM_001122606	NP_001116078	P13473	LAMP2_HUMAN	Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant C, mRNA.	199	Hinge.				platelet activation|platelet degranulation	endosome membrane|integral to membrane|late endosome|lysosomal membrane|membrane fraction|plasma membrane|platelet dense granule membrane				endometrium(4)|large_intestine(2)|lung(5)|ovary(2)|urinary_tract(2)	15						TGTATGGTGGGTGCCACTGTT	0.408000													8	84					0	0	1	0	0
ABCA6	23460	broad.mit.edu	37	17	67081770	67081770	+	Missense_Mutation	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr17:67081770C>T	uc002jhw.1	-	30	4200	c.4025G>A	c.(4024-4026)gGa>gAa	p.G1342E		NM_080284	NP_525023	Q8N139	ABCA6_HUMAN	Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 6 (ABCA6), mRNA.	1342	ABC transporter 2.				transport	integral to membrane	ATP binding|ATPase activity			breast(6)|endometrium(5)|kidney(17)|large_intestine(18)|lung(20)|ovary(3)|prostate(2)|skin(5)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	82	Breast(10;5.65e-12)					CACTACCTCTCCAGCAGTTGG	0.343000													10	213					0	0	1	0	0
MGC70870	403340	broad.mit.edu	37	GL000205.1	117012	117012	+	RNA	SNP	C	C	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chrGL000205.1:117012C>A	uc002kgk.4	+	0		c.390C>A								Homo sapiens C-terminal binding protein 2 pseudogene (MGC70870), non-coding RNA.																		ACCAAAGAAGCTGTATTCCCT	0.478000													4	9					0.150653	0.150653	1	1	0
ASXL3	80816	broad.mit.edu	37	18	31224902	31224902	+	Missense_Mutation	SNP	A	A	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr18:31224902A>G	uc010dmg.1	+	2	237	c.182A>G	c.(181-183)aAc>aGc	p.N61S	ASXL3_uc002kxq.2_5'UTR	NM_030632	NP_085135	Q9C0F0	ASXL3_HUMAN	Homo sapiens additional sex combs like 3 (Drosophila) (ASXL3), mRNA.	61					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	metal ion binding	p.F60S(1)		breast(3)|endometrium(3)|kidney(3)|large_intestine(6)|lung(22)|ovary(2)|pancreas(1)|skin(2)|urinary_tract(1)	43						CTTCACACTAACACTCGAATA	0.393000													4	32					0	0	1	0	0
FREM2	341640	broad.mit.edu	37	13	39438496	39438496	+	Missense_Mutation	SNP	A	A	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr13:39438496A>G	uc001uwv.3	+	15	8045	c.7736A>G	c.(7735-7737)aAg>aGg	p.K2579R	FREM2_uc001uww.3_Missense_Mutation_p.K665R	NM_207361	NP_997244	Q5SZK8	FREM2_HUMAN	Homo sapiens FRAS1 related extracellular matrix protein 2 (FREM2), mRNA.	2579					cell communication|homophilic cell adhesion|multicellular organismal development	integral to membrane|plasma membrane	calcium ion binding			NS(1)|breast(2)|central_nervous_system(2)|cervix(1)|endometrium(14)|haematopoietic_and_lymphoid_tissue(3)|kidney(8)|large_intestine(35)|lung(39)|ovary(9)|pancreas(2)|prostate(12)|skin(11)|upper_aerodigestive_tract(7)|urinary_tract(2)	148		Lung NSC(96;1.04e-07)|Prostate(109;0.00384)|Breast(139;0.00396)|Lung SC(185;0.0565)|Hepatocellular(188;0.114)		all cancers(112;3.32e-07)|Epithelial(112;1.66e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.00154)|BRCA - Breast invasive adenocarcinoma(63;0.00631)|GBM - Glioblastoma multiforme(144;0.0312)		GGAAACCACAAGTGCTCCAAC	0.438000													9	98					0	0	1	0	0
GRIPAP1	56850	broad.mit.edu	37	X	48840222	48840222	+	Missense_Mutation	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chrX:48840222C>T	uc004dly.1	-	14	1272	c.1237G>A	c.(1237-1239)Gag>Aag	p.E413K	GRIPAP1_uc004dlz.3_Missense_Mutation_p.E303K|GRIPAP1_uc004dma.3_Missense_Mutation_p.E360K	NM_020137	NP_064522	Q4V328	GRAP1_HUMAN	Homo sapiens GRIP1 associated protein 1 (GRIPAP1), transcript variant 1, mRNA.	413						early endosome				breast(2)|endometrium(1)|kidney(1)|large_intestine(4)|lung(2)	10						GTCAACTGCTCCTTCTCCTGC	0.507000													11	174					0	0	1	0	0
TCEB3B	51224	broad.mit.edu	37	18	44560193	44560193	+	Silent	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr18:44560193G>A	uc002lcr.1	-	0	1796	c.1443C>T	c.(1441-1443)gaC>gaT	p.D481D	KATNAL2_uc010dnq.1_Intron|KATNAL2_uc002lco.3_Intron	NM_016427	NP_057511	Q8IYF1	ELOA2_HUMAN	Homo sapiens transcription elongation factor B polypeptide 3B (elongin A2) (TCEB3B), mRNA.	481					regulation of transcription elongation, DNA-dependent|transcription from RNA polymerase II promoter	integral to membrane|nucleus	DNA binding			breast(1)|cervix(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(15)|lung(24)|ovary(2)|pancreas(2)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	58						AGGTCATGGAGTCAGAATCCG	0.582000													43	65					0	0	1	0	0
EYA4	2070	broad.mit.edu	37	6	133849920	133849920	+	Missense_Mutation	SNP	G	G	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr6:133849920G>T	uc011ecs.2	+	19	2231	c.1915G>T	c.(1915-1917)Gca>Tca	p.A639S	EYA4_uc011ecq.2_Missense_Mutation_p.A579S|EYA4_uc011ecr.2_Intron|EYA4_uc003qec.4_Missense_Mutation_p.A633S|EYA4_uc003qed.4_Missense_Mutation_p.A633S|EYA4_uc003qee.4_Missense_Mutation_p.A610S|BC041459_uc003qeg.1_Intron	NM_004100	NP_004091	O95677	EYA4_HUMAN	Homo sapiens eyes absent homolog 4 (Drosophila) (EYA4), transcript variant 1, mRNA.	633					DNA repair|anatomical structure morphogenesis|chromatin modification|multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent|visual perception	cytoplasm|nucleus	metal ion binding|protein tyrosine phosphatase activity	p.Y638N(1)		breast(1)|central_nervous_system(3)|endometrium(5)|kidney(2)|large_intestine(11)|lung(25)|skin(1)	48	Colorectal(23;0.221)			GBM - Glioblastoma multiforme(68;0.00457)|OV - Ovarian serous cystadenocarcinoma(155;0.0152)		TCTCCACCAAGCACTGGAATT	0.453000													12	207					3.27435e-08	3.65636e-08	1	1	0
ZNF709	163051	broad.mit.edu	37	19	12574997	12574997	+	Missense_Mutation	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr19:12574997C>T	uc002mtv.4	-	3	1900	c.1739G>A	c.(1738-1740)aGg>aAg	p.R580K	ZNF709_uc002mtw.4_Missense_Mutation_p.R548K|ZNF709_uc002mtx.4_Missense_Mutation_p.R580K	NM_152601	NP_689814	Q8N972	ZN709_HUMAN	Homo sapiens zinc finger protein 709 (ZNF709), mRNA.	580					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(3)|upper_aerodigestive_tract(3)	6						AGTGTGAGTCCTTTCATGCAT	0.423000													47	109					0	0	1	0	0
FPR3	2359	broad.mit.edu	37	19	52327625	52327625	+	Silent	SNP	T	T	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr19:52327625T>A	uc002pxt.1	+	1	808	c.624T>A	c.(622-624)atT>atA	p.I208I	FPR3_uc021uyq.1_Silent_p.I208I	NM_002030	NP_002021	P25089	FPR3_HUMAN	Homo sapiens formyl peptide receptor 3 (FPR3), mRNA.	208					cellular component movement|chemotaxis	integral to membrane|plasma membrane	N-formyl peptide receptor activity			NS(1)|breast(3)|endometrium(3)|kidney(1)|large_intestine(5)|lung(17)|ovary(1)|prostate(1)|skin(3)	35						ACTTCATTATTGGCTTCAGCG	0.458000													58	70					0	0	1	0	0
ITGA3	3675	broad.mit.edu	37	17	48148253	48148253	+	Missense_Mutation	SNP	A	A	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr17:48148253A>G	uc010dbm.3	+	4	1174	c.710A>G	c.(709-711)tAt>tGt	p.Y237C	ITGA3_uc010dbl.3_Missense_Mutation_p.Y237C	NM_005501	NP_005492	P26006	ITA3_HUMAN	Homo sapiens integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (ITGA3), transcript variant b, mRNA.	237					blood coagulation|cell-matrix adhesion|integrin-mediated signaling pathway|leukocyte migration	cell surface|integrin complex	protein binding|receptor activity			endometrium(3)|kidney(2)|large_intestine(7)|lung(11)|ovary(2)|pancreas(1)|prostate(1)|skin(2)|stomach(2)	31						TTATCTGAGTATAGTTACAAG	0.502000													74	103					0	0	1	0	0
KIF13B	23303	broad.mit.edu	37	8	29037680	29037680	+	Nonsense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr8:29037680G>A	uc003xhh.4	-	7	720	c.661C>T	c.(661-663)Cga>Tga	p.R221*	KIF13B_uc003xhj.2_Nonsense_Mutation_p.R118*|KIF13B_uc010lvf.1_Nonsense_Mutation_p.R157*	NM_015254	NP_056069	Q9NQT8	KI13B_HUMAN	Homo sapiens kinesin family member 13B (KIF13B), mRNA.	221	Kinesin-motor.				T cell activation|microtubule-based movement|protein targeting|signal transduction	cytoplasm|microtubule	ATP binding|microtubule motor activity|protein kinase binding			endometrium(6)|kidney(1)|lung(20)|urinary_tract(1)	28		Ovarian(32;0.000536)		KIRC - Kidney renal clear cell carcinoma(542;0.152)|Kidney(114;0.181)		GCATGGGATCGGCTACTCTCC	0.438000													100	165					0	0	1	0	0
abParts	0	broad.mit.edu	37	2	89976362	89976362	+	RNA	SNP	A	A	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr2:89976362A>G	uc010yts.2	+	10		c.1659A>G								Parts of antibodies, mostly variable regions.																		AAGGTTTCTAACTGGGACTCT	0.493000													17	380					0	0	1	0	0
TRIO	7204	broad.mit.edu	37	5	14497115	14497115	+	Missense_Mutation	SNP	G	G	C			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr5:14497115G>C	uc003jff.3	+	49	8014	c.8008G>C	c.(8008-8010)Gta>Cta	p.V2670L	TRIO_uc003jfg.3_Non-coding_Transcript	NM_007118	NP_009049	O75962	TRIO_HUMAN	Homo sapiens triple functional domain (PTPRF interacting) (TRIO), mRNA.	2670					apoptosis|axon guidance|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|transmembrane receptor protein tyrosine phosphatase signaling pathway	cytosol	ATP binding|Rho guanyl-nucleotide exchange factor activity|protein serine/threonine kinase activity			NS(2)|breast(6)|central_nervous_system(4)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(21)|lung(34)|ovary(4)|prostate(2)|skin(11)|stomach(3)|upper_aerodigestive_tract(3)|urinary_tract(4)	118	Lung NSC(4;0.000742)					CAGCAACAAGGTATCTGTGAA	0.498000													33	81					0	0	1	0	0
ATXN7	6314	broad.mit.edu	37	3	63981359	63981359	+	Missense_Mutation	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr3:63981359C>T	uc003dlv.3	+	11	2414	c.1861C>T	c.(1861-1863)Cat>Tat	p.H621Y	ATXN7_uc003dlw.4_Missense_Mutation_p.H621Y|ATXN7_uc021wzy.1_Missense_Mutation_p.H621Y|ATXN7_uc011bfn.2_Missense_Mutation_p.H476Y	NM_000333	NP_000324	O15265	ATX7_HUMAN	Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7a, mRNA.	621					cell death|histone deubiquitination|nucleus organization|regulation of transcription, DNA-dependent|transcription, DNA-dependent|visual perception	cytoplasm|nuclear matrix|nucleolus	protein binding|zinc ion binding			NS(1)|breast(1)|endometrium(6)|kidney(2)|large_intestine(7)|lung(12)|prostate(2)|stomach(1)|urinary_tract(3)	35		Prostate(884;0.0181)		BRCA - Breast invasive adenocarcinoma(55;0.000614)|KIRC - Kidney renal clear cell carcinoma(15;0.00294)|Kidney(15;0.00305)		GGTACCAGCTCATGGAACCAC	0.527000													83	209					0	0	1	0	0
WWP1	11059	broad.mit.edu	37	8	87443954	87443954	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr8:87443954G>A	uc003ydt.3	+	13	1863	c.1583G>A	c.(1582-1584)cGc>cAc	p.R528H	WWP1_uc010mai.3_Missense_Mutation_p.R304H	NM_007013	NP_008944	Q9H0M0	WWP1_HUMAN	Homo sapiens WW domain containing E3 ubiquitin protein ligase 1 (WWP1), mRNA.	528	WW 4.				central nervous system development|entry of virus into host cell|negative regulation of transcription, DNA-dependent|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|signal transduction	cytoplasm|nucleus|plasma membrane|ubiquitin ligase complex	protein binding|ubiquitin-protein ligase activity			endometrium(3)|kidney(2)|large_intestine(9)|liver(4)|lung(10)|prostate(2)|urinary_tract(1)	31						AAAGATCCTCGCAATGGGAAG	0.388000													5	105					0	0	1	0	0
DCUN1D3	123879	broad.mit.edu	37	16	20871250	20871250	+	Silent	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr16:20871250G>A	uc002dhz.3	-	2	1014	c.873C>T	c.(871-873)ctC>ctT	p.L291L	ERI2_uc002dht.3_Intron	NM_173475	NP_775746	Q8IWE4	DCNL3_HUMAN	Homo sapiens DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) (DCUN1D3), mRNA.	291					negative regulation of S phase of mitotic cell cycle|negative regulation of cell growth|positive regulation of apoptosis|response to UV-C|response to gamma radiation	perinuclear region of cytoplasm				NS(2)|breast(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(3)|ovary(2)	14				GBM - Glioblastoma multiforme(48;0.249)		GCCCTGAGCTGAGTGCACCTC	0.577000													68	89					0	0	1	0	0
OR10J5	127385	broad.mit.edu	37	1	159505502	159505502	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr1:159505502G>A	uc010piw.2	-	0	296	c.296C>T	c.(295-297)aCa>aTa	p.T99I		NM_001004469	NP_001004469	Q8NHC4	O10J5_HUMAN	Homo sapiens olfactory receptor, family 10, subfamily J, member 5 (OR10J5), mRNA.	99					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			kidney(1)|large_intestine(4)|lung(9)|ovary(1)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)	22	all_hematologic(112;0.0429)					GAACATTTGTGTAGCACAGCC	0.463000													6	191					0	0	1	0	0
TBC1D3P1-DHX40P1	653645	broad.mit.edu	37	17	58066651	58066651	+	Silent	SNP	C	C	T	rs144367363	by1000genomes	TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr17:58066651C>T	uc002iyf.2	-	8	721	c.486G>A	c.(484-486)caG>caA	p.Q162Q	AK097658_uc002iye.1_Intron					Homo sapiens TBC1D3P1-DHX40P1 readthrough (non-protein coding) (TBC1D3P1-DHX40P1), non-coding RNA.																		ACTGGTAAAGCTGTTTAAGAG	0.333000													3	125					0	0	1	0	0
RPL13	6137	broad.mit.edu	37	16	89627425	89627425	+	Missense_Mutation	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr16:89627425C>T	uc002fnm.2	+	1	134	c.58C>T	c.(58-60)Cgg>Tgg	p.R20W	RPL13_uc010vpj.2_Missense_Mutation_p.R20W|RPL13_uc021tmt.1_Missense_Mutation_p.R20W|RPL13_uc002fnn.2_Missense_Mutation_p.R20W|RPL13_uc002fno.2_Missense_Mutation_p.R20W|SNORD68_uc010cim.1_5'Flank	NM_000977	NP_150254	P26373	RL13_HUMAN	Homo sapiens ribosomal protein L13 (RPL13), transcript variant 1, mRNA.	20					endocrine pancreas development|translational elongation|translational termination|viral transcription	cytosolic ribosome	RNA binding|protein binding|structural constituent of ribosome			lung(3)|skin(1)|upper_aerodigestive_tract(2)	6		all_hematologic(23;0.0748)		all cancers(4;1.15e-07)|OV - Ovarian serous cystadenocarcinoma(4;7.8e-06)|BRCA - Breast invasive adenocarcinoma(80;0.0139)		GGACTGGCAGCGGCGCGTGGC	0.711000													22	25					0	0	1	0	0
LOC494141	494141	broad.mit.edu	37	11	18231915	18231915	+	RNA	SNP	T	T	C	rs2251440	by1000genomes	TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr11:18231915T>C	uc009yhh.3	+	1		c.939T>C			LOC494141_uc001mnx.4_Non-coding_Transcript|LOC494141_uc009yhi.2_Non-coding_Transcript					Homo sapiens mitochondrial carrier triple repeat 1 pseudogene (LOC494141), transcript variant 1, non-coding RNA.																		TTCCTGTTTTTTCCAATTAAT	0.438000													4	230					0	0	1	0	0
ITGA8	8516	broad.mit.edu	37	10	15688856	15688856	+	Missense_Mutation	SNP	T	T	C			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr10:15688856T>C	uc001ioc.1	-	11	1196	c.1196A>G	c.(1195-1197)gAt>gGt	p.D399G	ITGA8_uc010qcb.1_Missense_Mutation_p.D384G	NM_003638	NP_003629	P53708	ITA8_HUMAN	Homo sapiens integrin, alpha 8 (ITGA8), mRNA.	399					cell differentiation|cell-cell adhesion|cell-matrix adhesion|integrin-mediated signaling pathway|nervous system development	integrin complex	receptor activity			NS(2)|breast(1)|cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(10)|lung(57)|ovary(3)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(3)	96						ATTGTATCCATCTTGGTTCAG	0.468000													6	71					0	0	1	0	0
ATG10	83734	broad.mit.edu	37	5	81549249	81549249	+	Splice_Site	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr5:81549249G>A	uc003khs.3	+	8	1096	c.667_splice	c.e8+1		ATG10_uc003khr.3_Splice_Site|ATG10_uc010jas.3_Splice_Site	NM_001131028	NP_113670	Q9H0Y0	ATG10_HUMAN	Homo sapiens ATG10 autophagy related 10 homolog (S. cerevisiae) (ATG10), transcript variant 3, mRNA.						autophagy in response to ER overload|positive regulation of protein modification process|protein lipidation|protein modification by small protein conjugation|protein transport	cytoplasm	Atg12 ligase activity|protein binding			central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(4)|prostate(2)	9		Lung NSC(167;0.0258)|all_lung(232;0.0294)|Ovarian(174;0.135)		OV - Ovarian serous cystadenocarcinoma(54;9.94e-41)|Epithelial(54;6.3e-36)|all cancers(79;2.31e-30)		CCTTAACAAGGTAAAAGAAAA	0.408000													4	63					0	0	1	0	0
YSK4	80122	broad.mit.edu	37	2	135738691	135738691	+	Missense_Mutation	SNP	C	C	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr2:135738691C>G	uc002tue.1	-	8	3651	c.3620G>C	c.(3619-3621)tGt>tCt	p.C1207S	YSK4_uc002tuf.1_Missense_Mutation_p.C389S|YSK4_uc010fnc.1_Missense_Mutation_p.C341S|YSK4_uc010fnd.1_Missense_Mutation_p.C1094S|YSK4_uc010zbg.1_Missense_Mutation_p.C339S|YSK4_uc021vpz.1_Missense_Mutation_p.C68S|YSK4_uc002tuh.4_Missense_Mutation_p.C935S|YSK4_uc002tui.4_3'UTR	NM_025052	NP_079328	Q56UN5	YSK4_HUMAN	Homo sapiens YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae) (YSK4), transcript variant 1, mRNA.	1207	Protein kinase.						ATP binding|protein serine/threonine kinase activity			breast(1)|endometrium(2)|large_intestine(9)|lung(8)|ovary(2)|prostate(1)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	27				BRCA - Breast invasive adenocarcinoma(221;0.112)		ACGCCTGGCACAGCCAAAGTC	0.458000													20	51					0	0	1	0	0
LOC646214	646214	broad.mit.edu	37	15	21937331	21937331	+	RNA	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr15:21937331G>A	uc010tzj.1	-	0		c.3409C>T								Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 2 pseudogene (LOC646214), non-coding RNA.																		CCAGTGCAACGTCAGTAGCAG	0.348000													3	17					0	0	1	0	0
AHNAK2	113146	broad.mit.edu	37	14	105412335	105412335	+	Silent	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr14:105412335C>T	uc010axc.1	-	6	9573	c.9453G>A	c.(9451-9453)ccG>ccA	p.P3151P	AHNAK2_uc021seo.1_Intron|AHNAK2_uc001ypx.2_Silent_p.P3051P	NM_138420	NP_612429	Q8IVF2	AHNK2_HUMAN	Homo sapiens AHNAK nucleoprotein 2 (AHNAK2), mRNA.	3151						nucleus		p.P3151P(1)		cervix(4)|endometrium(4)|large_intestine(3)|lung(14)|ovary(2)|prostate(2)|skin(1)|stomach(3)	33		all_cancers(154;0.115)|Melanoma(154;0.155)|all_epithelial(191;0.183)	all cancers(16;0.000479)|OV - Ovarian serous cystadenocarcinoma(23;0.00659)|Epithelial(46;0.0151)|GBM - Glioblastoma multiforme(11;0.116)			CCCCGAACGACGGCATCTTGA	0.602000													4	50					0	0	1	0	0
LRRTM4	80059	broad.mit.edu	37	2	77746638	77746638	+	Missense_Mutation	SNP	G	G	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr2:77746638G>T	uc002snr.3	-	2	772	c.357C>A	c.(355-357)aaC>aaA	p.N119K	LRRTM4_uc002snq.3_Missense_Mutation_p.N119K|LRRTM4_uc002sns.2_Missense_Mutation_p.N119K|LRRTM4_uc002snt.2_Missense_Mutation_p.N120K	NM_001134745	NP_001128217	Q86VH4	LRRT4_HUMAN	Homo sapiens leucine rich repeat transmembrane neuronal 4 (LRRTM4), transcript variant 1, mRNA.	119						integral to membrane				autonomic_ganglia(1)|endometrium(1)|large_intestine(6)|lung(49)|ovary(2)|pancreas(3)|prostate(1)|upper_aerodigestive_tract(1)	64				Colorectal(11;0.059)		AAGTAATTTTGTTGGAGCTTA	0.373000													22	62					3.01185e-09	3.42023e-09	1	1	0
PRC1	9055	broad.mit.edu	37	15	91517424	91517424	+	Missense_Mutation	SNP	G	G	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr15:91517424G>T	uc002bqm.3	-	10	1560	c.1403C>A	c.(1402-1404)cCt>cAt	p.P468H	PRC1_uc002bqn.3_Missense_Mutation_p.P468H|PRC1_uc002bqo.3_Missense_Mutation_p.P468H|PRC1_uc010uqs.2_Missense_Mutation_p.P427H	NM_003981	NP_003972	O43663	PRC1_HUMAN	Homo sapiens protein regulator of cytokinesis 1 (PRC1), transcript variant 1, mRNA.	468	Unstructured, Arg/Lys rich.				cytokinesis|mitotic spindle elongation	cytoplasm|nucleus|spindle microtubule|spindle pole	protein binding	p.P468R(2)		endometrium(1)|kidney(2)|large_intestine(7)|lung(9)|ovary(3)|prostate(1)|skin(2)	25	Lung NSC(78;0.0987)|all_lung(78;0.175)					AGGTGTTCGAGGAGCGCTGCC	0.498000													17	168					2.39187e-15	2.76303e-15	1	1	0
MGC70870	403340	broad.mit.edu	37	GL000205.1	116939	116939	+	RNA	SNP	G	G	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chrGL000205.1:116939G>T	uc002kgk.4	+	0		c.317G>T								Homo sapiens C-terminal binding protein 2 pseudogene (MGC70870), non-coding RNA.																		GAGATTCGTTGGTGGCTGCGC	0.557000													2	4					0.0784	0.0795879	1	1	0
IGFN1	91156	broad.mit.edu	37	1	201166405	201166405	+	Silent	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr1:201166405C>T	uc001gwc.3	+	4	457	c.327C>T	c.(325-327)taC>taT	p.Y109Y	IGFN1_uc001gwb.3_Non-coding_Transcript	NM_001164586	NP_001158058			Homo sapiens immunoglobulin-like and fibronectin type III domain containing 1 (IGFN1), mRNA.											autonomic_ganglia(2)|cervix(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(21)|ovary(2)|pancreas(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	45						TAAATGCGTACGGAGAGGCCG	0.557000													25	69					0	0	1	0	0
RICTOR	253260	broad.mit.edu	37	5	38947463	38947463	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr5:38947463G>A	uc003jlo.2	-	32	4311	c.4289C>T	c.(4288-4290)tCt>tTt	p.S1430F	RICTOR_uc003jlp.2_Missense_Mutation_p.S1406F|RICTOR_uc010ivf.2_Missense_Mutation_p.S1121F	NM_152756	NP_689969	Q6R327	RICTR_HUMAN	Homo sapiens RPTOR independent companion of MTOR, complex 2 (RICTOR), mRNA.	1406					T cell costimulation|actin cytoskeleton reorganization|embryo development|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of TOR signaling cascade|regulation of protein kinase B signaling cascade	TORC2 complex|cytosol	protein binding			NS(1)|breast(4)|central_nervous_system(2)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(14)|lung(33)|ovary(3)|prostate(3)|skin(5)	75	all_lung(31;0.000396)					CACTGAGGAAGATCGTTGCAG	0.388000													5	176					0	0	1	0	0
FAM75D1	389763	broad.mit.edu	37	9	84608041	84608041	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr9:84608041G>A	uc004amn.3	+	3	2703	c.2656G>A	c.(2656-2658)Gtt>Att	p.V886I		NM_001001670	NP_001001670	Q6ZQQ2	F75D1_HUMAN	Homo sapiens family with sequence similarity 75, member D1 (FAM75D1), mRNA.	886						integral to membrane				cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(11)|lung(57)|prostate(3)|skin(3)|stomach(1)|urinary_tract(1)	88						GGACCACTGCGTTGATACTTC	0.438000													85	95					0	0	1	0	0
MAML2	84441	broad.mit.edu	37	11	95825407	95825407	+	Silent	SNP	C	C	T	rs61901862	by1000genomes	TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr11:95825407C>T	uc001pfw.1	-	1	3073	c.1788G>A	c.(1786-1788)caG>caA	p.Q596Q		NM_032427	NP_115803	Q8IZL2	MAML2_HUMAN	Homo sapiens mastermind-like 2 (Drosophila) (MAML2), mRNA.	596					Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear speck	transcription coactivator activity	p.Q596Q(2)	CRTC3/MAML2(26)|CRTC1/MAML2(516)	breast(2)|cervix(1)|endometrium(11)|kidney(4)|large_intestine(8)|lung(12)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	43		Acute lymphoblastic leukemia(157;2.63e-05)|all_hematologic(158;0.00837)				gctgctgctgctgctgctgtt	0.532000			T	"""MECT1, CRTC3"""	salivary gland mucoepidermoid								24	135					0	0	1	0	0
CR1	1378	broad.mit.edu	37	1	207669654	207669654	+	Silent	SNP	G	G	C			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr1:207669654G>C	uc001hfy.3	+	0	182	c.42G>C	c.(40-42)ccG>ccC	p.P14P	CR1_uc009xcl.1_Silent_p.P14P|CR1_uc001hfx.3_Silent_p.P14P|CR1_uc021pij.1_Silent_p.P14P|CR1_uc010psg.1_Silent_p.P14P|CR1_uc009xcj.1_Silent_p.P14P|CR1_uc009xck.1_Silent_p.P14P	NM_000573	NP_000564	P17927	CR1_HUMAN	Homo sapiens complement component (3b/4b) receptor 1 (Knops blood group) (CR1), transcript variant F, mRNA.	14					complement activation, classical pathway|innate immune response	integral to plasma membrane	complement receptor activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(9)|kidney(11)|large_intestine(13)|lung(33)|ovary(3)|prostate(6)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	82						CTGTCGGGCCGCCGGCGCCCG	0.632000													3	26					0	0	1	0	0
CCDC132	55610	broad.mit.edu	37	7	92932815	92932815	+	Missense_Mutation	SNP	T	T	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr7:92932815T>G	uc003umo.3	+	16	1533	c.1405T>G	c.(1405-1407)Tgg>Ggg	p.W469G	CCDC132_uc003ump.3_Missense_Mutation_p.W439G|CCDC132_uc003umr.3_Non-coding_Transcript|CCDC132_uc011khz.2_Missense_Mutation_p.W189G	NM_017667	NP_060137	Q96JG6	CC132_HUMAN	Homo sapiens coiled-coil domain containing 132 (CCDC132), transcript variant 1, mRNA.	469										endometrium(1)|large_intestine(2)|lung(5)	8	all_cancers(62;2.64e-11)|all_epithelial(64;1.4e-10)|Breast(17;0.000675)|Lung NSC(181;0.0618)|all_lung(186;0.0837)		STAD - Stomach adenocarcinoma(171;0.000302)			GAATGAGACTTGGGAACTTTG	0.348000													12	16					0	0	1	0	0
KIAA1755	85449	broad.mit.edu	37	20	36870194	36870194	+	Silent	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr20:36870194C>T	uc002xhy.1	-	2	611	c.339G>A	c.(337-339)gaG>gaA	p.E113E	KIAA1755_uc002xhz.1_Silent_p.E113E	NM_001029864	NP_001025035	Q5JYT7	K1755_HUMAN	Homo sapiens KIAA1755 (KIAA1755), mRNA.	113								p.E113K(1)		breast(2)|endometrium(3)|kidney(1)|large_intestine(5)|lung(31)|ovary(5)|pancreas(2)|skin(4)|stomach(1)	54		Myeloproliferative disorder(115;0.00874)				CAGACTGCTCCTCCTGGGGCT	0.557000													34	112					0	0	1	0	0
ACAD8	27034	broad.mit.edu	37	11	134131026	134131026	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr11:134131026G>A	uc001qhk.3	+	6	855	c.794G>A	c.(793-795)gGc>gAc	p.G265D	ACAD8_uc010sco.1_3'UTR|ACAD8_uc010scp.1_Non-coding_Transcript|ACAD8_uc010scq.2_Missense_Mutation_p.G188D|ACAD8_uc001qhl.3_Missense_Mutation_p.G138D|ACAD8_uc010scr.1_3'UTR|ACAD8_uc009zde.1_3'UTR	NM_014384	NP_055199	Q9UKU7	ACAD8_HUMAN	Homo sapiens acyl-CoA dehydrogenase family, member 8 (ACAD8), nuclear gene encoding mitochondrial protein, mRNA.	265					branched chain family amino acid catabolic process|lipid metabolic process|regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrial matrix	acyl-CoA dehydrogenase activity|flavin adenine dinucleotide binding			endometrium(4)|large_intestine(3)|lung(5)|ovary(1)|urinary_tract(1)	14	all_hematologic(175;0.127)	all_cancers(12;8e-23)|all_epithelial(12;2.59e-16)|all_lung(97;1.19e-05)|Lung NSC(97;2.76e-05)|Breast(109;0.000182)|all_neural(223;0.0189)|Medulloblastoma(222;0.0245)|Esophageal squamous(93;0.0559)		Epithelial(10;1.92e-10)|all cancers(11;2.26e-09)|BRCA - Breast invasive adenocarcinoma(10;8.73e-09)|OV - Ovarian serous cystadenocarcinoma(99;0.00154)|Lung(977;0.21)		GAGGGGCAGGGCTTCCTCATT	0.587000													55	70					0	0	1	0	0
PCDH11X	27328	broad.mit.edu	37	X	91133625	91133625	+	Missense_Mutation	SNP	C	C	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chrX:91133625C>A	uc004efk.2	+	1	3231	c.2386C>A	c.(2386-2388)Cca>Aca	p.P796T	PCDH11X_uc004efl.2_Missense_Mutation_p.P796T|PCDH11X_uc010nmv.2_Missense_Mutation_p.P796T|PCDH11X_uc004efm.2_Missense_Mutation_p.P796T|PCDH11X_uc004efn.2_Missense_Mutation_p.P796T|PCDH11X_uc004efo.2_Missense_Mutation_p.P796T|PCDH11X_uc004efh.2_Missense_Mutation_p.P796T|PCDH11X_uc004efj.1_Missense_Mutation_p.P796T	NM_032968	NP_116750	Q9BZA7	PC11X_HUMAN	Homo sapiens protocadherin 11 X-linked (PCDH11X), transcript variant c, mRNA.	796					homophilic cell adhesion	integral to plasma membrane	calcium ion binding			NS(1)|autonomic_ganglia(1)|biliary_tract(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(30)|liver(4)|lung(92)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(1)	159						ACCAGTGACCCCAAATACTGA	0.438000													181	241					8.09845e-80	1.00481e-79	1	1	0
TNXB	7148	broad.mit.edu	37	6	32037362	32037362	+	Missense_Mutation	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr6:32037362C>T	uc003nzl.2	-	14	5757	c.5555G>A	c.(5554-5556)cGt>cAt	p.R1852H		NM_019105	NP_061978	P22105	TENX_HUMAN	Homo sapiens tenascin XB (TNXB), transcript variant XB, mRNA.	1934					actin cytoskeleton organization|cell adhesion|collagen metabolic process|elastic fiber assembly|signal transduction	extracellular space|intracellular|proteinaceous extracellular matrix	heparin binding|integrin binding			endometrium(1)|kidney(1)|large_intestine(1)|lung(4)|prostate(1)	8						GGGGCCCACACGCTTGCCGTG	0.672000													7	81					0	0	1	0	0
TRPM5	29850	broad.mit.edu	37	11	2432685	2432685	+	Silent	SNP	C	C	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr11:2432685C>T	uc010qxl.2	-	17	2688	c.2679G>A	c.(2677-2679)gcG>gcA	p.A893A	TRPM5_uc001lwm.4_Silent_p.A893A|TRPM5_uc009ydn.3_Silent_p.A895A	NM_014555	NP_055370	Q9NZQ8	TRPM5_HUMAN	Homo sapiens transient receptor potential cation channel, subfamily M, member 5 (TRPM5), mRNA.	893						integral to membrane|plasma membrane	receptor activity|voltage-gated ion channel activity			breast(1)|central_nervous_system(1)|endometrium(4)|liver(1)|lung(8)|ovary(2)|prostate(2)|skin(2)|urinary_tract(2)	23		Medulloblastoma(188;0.0049)|Breast(177;0.00586)|all_epithelial(84;0.0075)|Ovarian(85;0.0256)|all_neural(188;0.0311)		BRCA - Breast invasive adenocarcinoma(625;0.00147)|LUSC - Lung squamous cell carcinoma(625;0.191)		GGTGCAGCAGCGCCTGGGTGG	0.632000													18	44					0	0	1	0	0
FLNC	2318	broad.mit.edu	37	7	128482660	128482660	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr7:128482660G>A	uc003vnz.4	+	14	2506	c.2297G>A	c.(2296-2298)cGg>cAg	p.R766Q	FLNC_uc003voa.4_Missense_Mutation_p.R766Q	NM_001458	NP_001449	Q14315	FLNC_HUMAN	Homo sapiens filamin C, gamma (FLNC), transcript variant 1, mRNA.	766					cell junction assembly	cytoskeleton|cytosol|plasma membrane|sarcomere	actin binding			biliary_tract(1)|breast(7)|central_nervous_system(1)|cervix(1)|endometrium(19)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(19)|lung(59)|ovary(2)|pancreas(2)|prostate(1)|skin(6)|upper_aerodigestive_tract(2)	128						CACCCCGAGCGGGTAAAGGTG	0.692000											OREG0018297	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	10	81					0	0	1	0	0
DDX11L11	0	broad.mit.edu	37	12	92119	92119	+	Missense_Mutation	SNP	T	T	C			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr12:92119T>C	uc010sdi.1	-	1	219	c.191A>G	c.(190-192)cAc>cGc	p.H64R	DDX11L11_uc010sdj.1_Non-coding_Transcript					SubName: Full=DEAD/H box polypeptide 11 like 11;																		CGCCAGGCAGTGGTGCAGCTG	0.592000													3	13					0	0	1	0	0
SHE	126669	broad.mit.edu	37	1	154471704	154471704	+	Missense_Mutation	SNP	A	A	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr1:154471704A>G	uc001ffb.3	-	1	626	c.602T>C	c.(601-603)tTa>tCa	p.L201S	SHE_uc001ffc.3_Non-coding_Transcript|TDRD10_uc001ffd.3_5'Flank|TDRD10_uc009wow.3_5'Flank	NM_001010846	NP_001010846	Q5VZ18	SHE_HUMAN	Homo sapiens Src homology 2 domain containing E (SHE), mRNA.	201										breast(4)|central_nervous_system(1)|kidney(2)|large_intestine(2)|lung(2)|ovary(2)|pancreas(1)	14	all_lung(78;1.72e-29)|Lung NSC(65;2.96e-27)|Hepatocellular(266;0.0877)|all_hematologic(923;0.088)		LUSC - Lung squamous cell carcinoma(543;0.185)			ATAGTCTTCTAAAATGATGAC	0.448000													30	79					0	0	1	0	0
abParts	0	broad.mit.edu	37	14	106539361	106539361	+	RNA	SNP	C	C	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr14:106539361C>A	uc021ser.1	-	2082		c.37785G>T								Parts of antibodies, mostly variable regions.																		CAGACTGCACCAGCTGCACCT	0.532000													3	16					0.014758	0.0152121	1	1	0
PROX1	5629	broad.mit.edu	37	1	214170147	214170147	+	Missense_Mutation	SNP	C	C	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr1:214170147C>A	uc001hkh.3	+	1	541	c.269C>A	c.(268-270)gCa>gAa	p.A90E	PROX1_uc001hkg.1_Missense_Mutation_p.A90E	NM_002763	NP_002754	Q92786	PROX1_HUMAN	Homo sapiens prospero homeobox 1 (PROX1), mRNA.	90					aorta smooth muscle tissue morphogenesis|atrial cardiac muscle tissue morphogenesis|brain development|dorsal spinal cord development|embryonic retina morphogenesis in camera-type eye|endocardium formation|hepatocyte differentiation|kidney development|lens fiber cell morphogenesis|lung development|lymphangiogenesis|negative regulation of bile acid biosynthetic process|negative regulation of cell proliferation|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of viral genome replication|neural tube development|olfactory placode formation|optic placode formation involved in camera-type eye formation|otic placode formation|pancreas development|positive regulation of S phase of mitotic cell cycle|positive regulation of cyclin-dependent protein kinase activity|positive regulation of endothelial cell migration|positive regulation of endothelial cell proliferation|positive regulation of heart growth|positive regulation of sarcomere organization|positive regulation of transcription, DNA-dependent|regulation of transcription involved in lymphatic endothelial cell fate commitment|skeletal muscle thin filament assembly|venous blood vessel morphogenesis|ventricular cardiac muscle tissue morphogenesis|ventricular cardiac myofibril development|ventricular septum morphogenesis	cytoplasm|nucleus	DBD domain binding|LBD domain binding|ligand-dependent nuclear receptor binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|transcription corepressor activity|transcription regulatory region DNA binding			autonomic_ganglia(1)|breast(3)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(6)|lung(15)|ovary(3)|prostate(2)|skin(4)	47				OV - Ovarian serous cystadenocarcinoma(81;0.0179)|all cancers(67;0.0488)|GBM - Glioblastoma multiforme(131;0.188)|Epithelial(68;0.219)		TTTCCAGGAGCAACCATAATT	0.488000													5	120					5.18039e-06	5.59816e-06	1	1	0
CILP2	148113	broad.mit.edu	37	19	19654855	19654855	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr19:19654855G>A	uc002nmw.4	+	7	1604	c.1519G>A	c.(1519-1521)Ggc>Agc	p.G507S	CILP2_uc002nmv.4_Missense_Mutation_p.G501S	NM_153221	NP_694953	Q8IUL8	CILP2_HUMAN	Homo sapiens cartilage intermediate layer protein 2 (CILP2), mRNA.	501						proteinaceous extracellular matrix	carbohydrate binding|carboxypeptidase activity	p.G507G(1)		NS(1)|breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(3)|large_intestine(3)|lung(17)|ovary(2)|prostate(2)|skin(1)|urinary_tract(1)	32						GGAGCCCATCGGCTTCACCGC	0.672000													20	42					0	0	1	0	0
SPAG7	9552	broad.mit.edu	37	17	4871031	4871031	+	Silent	SNP	A	A	C			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr17:4871031A>C	uc002gae.3	-	0	102	c.69T>G	c.(67-69)acT>acG	p.T23T	SPAG7_uc002gaf.3_Silent_p.T23T|DQ588877_uc021tof.1_5'Flank	NM_004890	NP_004881	O75391	SPAG7_HUMAN	Homo sapiens sperm associated antigen 7 (SPAG7), mRNA.	23						nucleus	nucleic acid binding|protein binding			central_nervous_system(1)|endometrium(1)|kidney(2)|lung(3)|ovary(2)|urinary_tract(1)	10						CCTTGCGCCGAGTCTCCTGGT	0.627000													14	46					0	0	1	0	0
CDH8	1006	broad.mit.edu	37	16	61687954	61687954	+	Missense_Mutation	SNP	A	A	C			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr16:61687954A>C	uc002eog.2	-	11	2913	c.1958T>G	c.(1957-1959)aTt>aGt	p.I653S		NM_001796	NP_001787	P55286	CADH8_HUMAN	Homo sapiens cadherin 8, type 2 (CDH8), mRNA.	653					adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			biliary_tract(1)|breast(3)|cervix(1)|endometrium(7)|kidney(6)|large_intestine(22)|liver(2)|lung(49)|ovary(6)|pancreas(2)|prostate(5)|skin(4)|urinary_tract(4)	112		Ovarian(137;0.0799)|Melanoma(118;0.16)		UCEC - Uterine corpus endometrioid carcinoma (183;0.196)|Epithelial(162;0.0155)|all cancers(182;0.0305)|OV - Ovarian serous cystadenocarcinoma(108;0.0499)|BRCA - Breast invasive adenocarcinoma(181;0.249)		ATCTTTGATAATTAATGGTTC	0.388000													37	86					0	0	1	0	0
RBM11	54033	broad.mit.edu	37	21	15599303	15599303	+	Missense_Mutation	SNP	G	G	T			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr21:15599303G>T	uc002yjo.4	+	4	577	c.535G>T	c.(535-537)Gat>Tat	p.D179Y	RBM11_uc002yjn.4_Missense_Mutation_p.D65Y|RBM11_uc002yjp.4_Missense_Mutation_p.D65Y	NM_144770	NP_658983	P57052	RBM11_HUMAN	Homo sapiens RNA binding motif protein 11 (RBM11), mRNA.	179							RNA binding|nucleotide binding			endometrium(3)|kidney(3)|lung(7)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	16				Epithelial(23;0.000314)|COAD - Colon adenocarcinoma(22;0.00242)|Colorectal(24;0.0129)|Lung(58;0.141)		TCATGTTCCAGATCTTGAGGC	0.458000													118	150					2.06835e-67	2.51962e-67	1	1	0
PMS2P3	5387	broad.mit.edu	37	7	75145521	75145521	+	RNA	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr7:75145521G>A	uc022agi.1	-	2		c.644C>T			PMS2P3_uc003udq.3_Non-coding_Transcript|PMS2P3_uc022agj.1_Non-coding_Transcript					Homo sapiens postmeiotic segregation increased 2 pseudogene 3 (PMS2P3), non-coding RNA.											lung(1)	1						GAAATCCACAGCCACATCTTT	0.473000													153	256					0	0	1	0	0
abParts	0	broad.mit.edu	37	14	106539367	106539367	+	RNA	SNP	C	C	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr14:106539367C>G	uc021ser.1	-	2082		c.37779G>C								Parts of antibodies, mostly variable regions.																		GCACCAGCTGCACCTGGGAGT	0.527000													3	16					0	0	1	0	0
CGN	57530	broad.mit.edu	37	1	151502428	151502428	+	Missense_Mutation	SNP	G	G	A			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr1:151502428G>A	uc009wmw.3	+	11	2294	c.2150G>A	c.(2149-2151)cGg>cAg	p.R717Q		NM_020770	NP_065821	Q9P2M7	CING_HUMAN	Homo sapiens cingulin (CGN), mRNA.	711	Glu-rich.					myosin complex|tight junction	actin binding|motor activity			NS(1)|central_nervous_system(3)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(8)|liver(1)|lung(14)|ovary(3)|pancreas(1)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	45	Ovarian(49;0.0273)|Hepatocellular(266;0.0997)|all_hematologic(923;0.127)|Melanoma(130;0.185)		LUSC - Lung squamous cell carcinoma(543;0.181)			CTGGGGCAGCGGCGGGCCGCA	0.652000													76	77					0	0	1	0	0
ATP1B1	481	broad.mit.edu	37	1	169094224	169094232	+	In_Frame_Del	DEL	AAAAGTACA	AAAAGTACA	-			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr1:169094224_169094232delAAAAGTACA	uc001gfr.1	+	2	450_458	c.329_337delAAAAGTACA	c.(328-339)gaaaagtacaaa>gaa	p.KYK111del		NM_001677	NP_001668	P05026	AT1B1_HUMAN	Homo sapiens ATPase, Na+/K+ transporting, beta 1 polypeptide (ATP1B1), mRNA.	111					ATP biosynthetic process|blood coagulation|leukocyte migration	sodium:potassium-exchanging ATPase complex	protein binding|sodium:potassium-exchanging ATPase activity			breast(1)|endometrium(1)|kidney(3)|large_intestine(3)|lung(4)|ovary(1)|prostate(1)	14	all_hematologic(923;0.208)					AGGTTCCTGGAAAAGTACAAAGATTCAGC	0.392													29	105	---	---	---	---					
RBM45	129831	broad.mit.edu	37	2	178988920	178988920	+	Frame_Shift_Del	DEL	A	A	-			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr2:178988920delA	uc002ulv.3	+	7	1227	c.1135delA	c.(1135-1137)aaafs	p.K379fs		NM_152945	NP_694453	Q8IUH3	RBM45_HUMAN	Homo sapiens RNA binding motif protein 45 (RBM45), mRNA.	381					cell differentiation|nervous system development	cytoplasm|nucleus	RNA binding|nucleotide binding	p.A382fs*7(2)|p.?(1)		endometrium(3)|kidney(2)|large_intestine(8)|lung(10)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	27			OV - Ovarian serous cystadenocarcinoma(117;0.00854)|Epithelial(96;0.00957)|all cancers(119;0.037)			TCCATCATGCAAAAAAAAAGC	0.353													8	125	---	---	---	---					
CSMD1	64478	broad.mit.edu	37	8	2808726	2808727	+	Frame_Shift_Ins	INS	-	-	G			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr8:2808726_2808727insG	uc022aqr.1	-	65	10500_10501	c.10110_10111insC	c.(10108-10113)cccgccfs	p.P3370fs	CSMD1_uc011kwj.2_Frame_Shift_Ins_p.P2685fs|CSMD1_uc010lrg.3_Frame_Shift_Ins_p.P1262fs	NM_033225	NP_150094	Q96PZ7	CSMD1_HUMAN	Homo sapiens CUB and Sushi multiple domains 1 (CSMD1), mRNA.	3371			Q -> H (in dbSNP:rs34337712).			integral to membrane		p.P3370P(1)|p.P3099P(1)		breast(20)|large_intestine(5)	25		all_cancers(1;5.7e-41)|all_epithelial(1;2.54e-36)|Lung NSC(1;7.54e-11)|all_lung(1;3.2e-10)|Hepatocellular(1;3.78e-05)|Breast(1;0.000196)|Myeloproliferative disorder(4;0.000374)|Esophageal squamous(1;0.0157)|Ovarian(12;0.091)|Renal(68;0.144)|Colorectal(14;0.234)		all cancers(1;5.03e-41)|Epithelial(1;4.78e-31)|Lung(1;1.14e-14)|LUSC - Lung squamous cell carcinoma(1;2.34e-14)|GBM - Glioblastoma multiforme(1;4.49e-10)|Colorectal(4;1.18e-07)|OV - Ovarian serous cystadenocarcinoma(1;3.2e-07)|BRCA - Breast invasive adenocarcinoma(1;6.17e-07)|COAD - Colon adenocarcinoma(4;0.000539)|READ - Rectum adenocarcinoma(4;0.00896)|Kidney(5;0.00957)|KIRC - Kidney renal clear cell carcinoma(5;0.0689)		GTTAGAGTGGCGGGTTGTCTTT	0.485													8	141	---	---	---	---					
AK057887	0	broad.mit.edu	37	16	84696989	84696990	+	RNA	DEL	AC	AC	-			TCGA-F9-A4JJ-01A-11D-A25F-10	TCGA-F9-A4JJ-10A-01D-A25F-10								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0e4d764c-5196-4566-ae92-e291608bcd73	05c628cd-15ec-47b2-851d-fdcd131c5172	g.chr16:84696989_84696990delAC	uc002fih.3	+	0		c.56_57delAC								Homo sapiens cDNA FLJ31635 fis, clone NT2RI2003420.																		ACTCCTGCAAACAGTTCCTAAA	0.569													4	4	---	---	---	---					
