Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut	init_n_lod
PTCHD2	57540	broad.mit.edu	37	1	11561896	11561896	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:11561896G>A	uc001ash.3	+	2	985	c.847G>A	c.(847-849)GGC>AGC	p.G283S	PTCHD2_uc001asi.1_Missense_Mutation_p.G283S	NM_020780	NP_065831	Q9P2K9	PTHD2_HUMAN	patched domain containing 2	283	Extracellular (Potential).				cholesterol homeostasis|regulation of lipid transport|smoothened signaling pathway	endoplasmic reticulum|integral to membrane|nuclear membrane	hedgehog receptor activity			skin(3)|ovary(2)|pancreas(1)|breast(1)	7	Ovarian(185;0.249)	Lung NSC(185;4.16e-05)|all_lung(284;4.76e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00205)|Hepatocellular(190;0.00913)|Ovarian(437;0.00965)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;3.13e-07)|COAD - Colon adenocarcinoma(227;4.83e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000325)|Kidney(185;0.000877)|KIRC - Kidney renal clear cell carcinoma(229;0.00273)|STAD - Stomach adenocarcinoma(313;0.00766)|READ - Rectum adenocarcinoma(331;0.0549)		CCTGGCGCGCGGCGACGCGGA	0.647000													6	18					0	0	1	0	0	
CSMD2	114784	broad.mit.edu	37	1	34070967	34070967	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:34070967C>T	uc001bxn.1	-	43	6482	c.6453G>A	c.(6451-6453)CCG>CCA	p.P2151P	CSMD2_uc001bxm.1_Silent_p.P2149P|CSMD2_uc001bxo.1_Silent_p.P1022P	NM_052896	NP_443128	Q7Z408	CSMD2_HUMAN	CUB and Sushi multiple domains 2	2151	Sushi 12.|Extracellular (Potential).					integral to membrane|plasma membrane	protein binding			ovary(6)|skin(5)|pancreas(1)	12		Myeloproliferative disorder(586;0.0294)|all_neural(195;0.249)				ATTGATACCCCGGGAGGCACT	0.577000													15	32					0	0	1	0	0	
DLGAP3	58512	broad.mit.edu	37	1	35365751	35365751	+	Missense_Mutation	SNP	C	T	T	rs146586197	by1000genomes	TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:35365751C>T	uc001byc.2	-	2	1231	c.1231G>A	c.(1231-1233)GGC>AGC	p.G411S		NM_001080418	NP_001073887	O95886	DLGP3_HUMAN	discs, large (Drosophila) homolog-associated	411					cell-cell signaling	cell junction|postsynaptic density|postsynaptic membrane				ovary(3)	3		Myeloproliferative disorder(586;0.0393)				TTGGGGCTGCCGTCTGAGTCT	0.642000													46	69					0	0	1	0	0	
COL11A1	1301	broad.mit.edu	37	1	103435780	103435780	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:103435780C>T	uc001dul.2	-	37	3175	c.2857G>A	c.(2857-2859)GAG>AAG	p.E953K	COL11A1_uc001duk.2_Missense_Mutation_p.E149K|COL11A1_uc001dum.2_Missense_Mutation_p.E965K|COL11A1_uc001dun.2_Missense_Mutation_p.E914K|COL11A1_uc009weh.2_Missense_Mutation_p.E837K	NM_001854	NP_001845	P12107	COBA1_HUMAN	alpha 1 type XI collagen isoform A	953	Triple-helical region.				collagen fibril organization|detection of mechanical stimulus involved in sensory perception of sound|visual perception	collagen type XI	extracellular matrix binding|extracellular matrix structural constituent|protein binding, bridging			ovary(6)|breast(3)|upper_aerodigestive_tract(1)|central_nervous_system(1)|pancreas(1)	12		all_epithelial(167;2.52e-07)|all_lung(203;3.11e-05)|Lung NSC(277;6.61e-05)|Breast(1374;0.181)		Lung(183;0.186)|all cancers(265;0.242)|Epithelial(280;0.248)		CTTACAGTCTCCCCACGTTGC	0.363000													13	48					0	0	1	0	0	
SHE	126669	broad.mit.edu	37	1	154461630	154461630	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:154461630C>T	uc001ffb.2	-	3	1008	c.921G>A	c.(919-921)GCG>GCA	p.A307A	SHE_uc001ffc.2_RNA	NM_001010846	NP_001010846	Q5VZ18	SHE_HUMAN	Src homology 2 domain containing E	307										breast(3)|ovary(2)|central_nervous_system(1)	6	all_lung(78;1.72e-29)|Lung NSC(65;2.96e-27)|Hepatocellular(266;0.0877)|all_hematologic(923;0.088)		LUSC - Lung squamous cell carcinoma(543;0.185)			CTGGGGGCCGCGCCTTCCCCT	0.662000													5	27					0	0	1	0	0	
OR10X1	128367	broad.mit.edu	37	1	158549094	158549094	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:158549094G>T	uc010pin.1	-	1	596	c.596C>A	c.(595-597)GCA>GAA	p.A199E		NM_001004477	NP_001004477	Q8NGY0	O10X1_HUMAN	olfactory receptor, family 10, subfamily X,	199	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)	1	all_hematologic(112;0.0378)					CCTAATAACTGCCAGCATATG	0.443000													17	33					1.96292e-10	2.10414e-10	1	1	0	
PAPPA2	60676	broad.mit.edu	37	1	176564113	176564113	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:176564113C>T	uc001gkz.2	+	3	2537	c.1373C>T	c.(1372-1374)GCG>GTG	p.A458V	PAPPA2_uc001gky.1_Missense_Mutation_p.A458V|PAPPA2_uc009www.2_RNA	NM_020318	NP_064714	Q9BXP8	PAPP2_HUMAN	pappalysin 2 isoform 1	458	Metalloprotease.				cell differentiation|proteolysis|regulation of cell growth	extracellular region|intracellular|membrane	metalloendopeptidase activity|zinc ion binding			ovary(7)|central_nervous_system(5)|skin(2)|lung(1)|breast(1)	16						GTCCTGACAGCGAGCTTTGAG	0.532000													19	48					0	0	1	0	0	
ASTN1	460	broad.mit.edu	37	1	176845761	176845761	+	Missense_Mutation	SNP	C	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:176845761C>A	uc001glc.2	-	21	3587	c.3375G>T	c.(3373-3375)TGG>TGT	p.W1125C	ASTN1_uc001glb.1_Missense_Mutation_p.W1125C|ASTN1_uc001gld.1_Missense_Mutation_p.W1125C	NM_004319	NP_004310	O14525	ASTN1_HUMAN	astrotactin isoform 1	1133	Fibronectin type-III 1.				cell migration|neuron cell-cell adhesion	integral to membrane				ovary(6)|skin(5)|central_nervous_system(2)|large_intestine(1)|lung(1)	15						TGTCCACTCCCCACAGCGTGA	0.602000													8	26					1.12685e-05	1.15794e-05	1	1	0	
ASPM	259266	broad.mit.edu	37	1	197070783	197070783	+	Missense_Mutation	SNP	G	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:197070783G>C	uc001gtu.2	-	18	7855	c.7598C>G	c.(7597-7599)TCT>TGT	p.S2533C	ASPM_uc001gtv.2_Intron|ASPM_uc001gtw.3_Missense_Mutation_p.S381C	NM_018136	NP_060606	Q8IZT6	ASPM_HUMAN	asp (abnormal spindle)-like, microcephaly	2533	IQ 27.				mitosis	cytoplasm|nucleus	calmodulin binding			ovary(4)|central_nervous_system(2)	6						AACCACAGCAGAATGCCATTG	0.343000													12	37					0	0	1	0	0	
CRB1	23418	broad.mit.edu	37	1	197404316	197404316	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:197404316C>T	uc001gtz.2	+	9	3458	c.3323C>T	c.(3322-3324)TCT>TTT	p.S1108F	CRB1_uc010poz.1_Missense_Mutation_p.S1084F|CRB1_uc010ppa.1_RNA|CRB1_uc009wza.2_Missense_Mutation_p.S996F|CRB1_uc010ppb.1_Intron|CRB1_uc010ppd.1_Missense_Mutation_p.S589F|CRB1_uc001gub.1_Missense_Mutation_p.S757F	NM_201253	NP_957705	P82279	CRUM1_HUMAN	crumbs homolog 1 precursor	1108	Extracellular (Potential).|Laminin G-like 3.				cell-cell signaling|establishment or maintenance of cell polarity	apical plasma membrane|extracellular region|integral to membrane	calcium ion binding|protein binding			ovary(5)|skin(3)|large_intestine(1)	9						ATTTATCTCTCTTACTTTGAA	0.363000													17	37					0	0	1	0	0	
KCTD3	51133	broad.mit.edu	37	1	215781446	215781446	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:215781446C>T	uc001hks.2	+	14	1691	c.1397C>T	c.(1396-1398)GCG>GTG	p.A466V	KCTD3_uc001hkt.2_Missense_Mutation_p.A466V|KCTD3_uc010pub.1_Missense_Mutation_p.A364V|KCTD3_uc009xdn.2_Intron	NM_016121	NP_057205	Q9Y597	KCTD3_HUMAN	potassium channel tetramerisation domain	466						voltage-gated potassium channel complex	protein binding|voltage-gated potassium channel activity			ovary(3)	3				all cancers(67;0.0164)|OV - Ovarian serous cystadenocarcinoma(81;0.019)|GBM - Glioblastoma multiforme(131;0.0862)|Epithelial(68;0.13)		ACTCCTTTAGCGTCATTCAAG	0.433000													22	53					0	0	1	0	0	
C1orf198	84886	broad.mit.edu	37	1	231004179	231004179	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr1:231004179C>T	uc001hub.2	-	1	124	c.80G>A	c.(79-81)CGA>CAA	p.R27Q	C1orf198_uc001huc.1_Intron|C1orf198_uc001hud.1_Intron	NM_032800	NP_116189	Q9H425	CA198_HUMAN	hypothetical protein LOC84886 isoform 1	27											0	Breast(184;0.0871)|Ovarian(103;0.183)	Prostate(94;0.178)				GAAGCGCTTTCGCTCCCGGTC	0.637000													9	12					0	0	1	0	0	
PPIF	10105	broad.mit.edu	37	10	81107467	81107467	+	Missense_Mutation	SNP	A	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr10:81107467A>T	uc001kai.2	+	1	248	c.163A>T	c.(163-165)AAC>TAC	p.N55Y	PPIF_uc001kaj.2_Missense_Mutation_p.N55Y	NM_005729	NP_005720	P30405	PPIF_HUMAN	peptidylprolyl isomerase F precursor	55	PPIase cyclophilin-type.				protein folding	membrane fraction|mitochondrial matrix	peptidyl-prolyl cis-trans isomerase activity			skin(1)	1	all_cancers(46;0.0893)|Breast(12;8.52e-05)|all_epithelial(25;0.00449)|Prostate(51;0.00985)		Epithelial(14;0.00242)|all cancers(16;0.0069)|Colorectal(32;0.229)		Dimethyl sulfoxide(DB01093)|L-Proline(DB00172)	CGTGGACGCCAACGGGAAGCC	0.522000													3	8					0	0	1	0	0	
HSPA12A	259217	broad.mit.edu	37	10	118434842	118434842	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr10:118434842G>A	uc001lct.2	-	12	1583	c.1478C>T	c.(1477-1479)GCG>GTG	p.A493V	HSPA12A_uc001lcu.2_Missense_Mutation_p.A410V	NM_025015	NP_079291	O43301	HS12A_HUMAN	heat shock 70kDa protein 12A	493							ATP binding			ovary(1)	1				all cancers(201;0.0158)		AGCCTGCACCGCCTGCTGCAG	0.647000													7	8					0	0	1	0	0	
DPYSL4	10570	broad.mit.edu	37	10	134006217	134006217	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr10:134006217G>A	uc009ybb.2	+	3	338	c.184G>A	c.(184-186)GGC>AGC	p.G62S		NM_006426	NP_006417	O14531	DPYL4_HUMAN	dihydropyrimidinase-like 4	62					axon guidance|pyrimidine base catabolic process	cytosol	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides			central_nervous_system(2)	2		all_cancers(35;4.33e-08)|all_epithelial(44;6.75e-06)|Lung NSC(174;0.0108)|all_lung(145;0.0173)|all_neural(114;0.0726)|Glioma(114;0.172)|Melanoma(40;0.175)|Colorectal(31;0.19)		OV - Ovarian serous cystadenocarcinoma(35;7.21e-05)|Epithelial(32;8.01e-05)|all cancers(32;9.29e-05)|BRCA - Breast invasive adenocarcinoma(275;0.206)		TGACGCCCACGGCCTGATGGT	0.582000													20	30					0	0	1	0	0	
ZNF195	7748	broad.mit.edu	37	11	3380678	3380678	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr11:3380678C>T	uc001lxt.2	-	6	1738	c.1560G>A	c.(1558-1560)AAG>AAA	p.K520K	uc001lxr.2_5'Flank|ZNF195_uc001lxv.2_Silent_p.K497K|ZNF195_uc001lxs.2_Silent_p.K448K|ZNF195_uc010qxr.1_Silent_p.K501K|ZNF195_uc009ydz.2_Silent_p.K475K|ZNF195_uc001lxu.2_Silent_p.K452K	NM_001130520	NP_001123992	O14628	ZN195_HUMAN	zinc finger protein 195 isoform 1	520					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Medulloblastoma(188;0.00106)|Breast(177;0.00328)|all_neural(188;0.00681)|Ovarian(85;0.00965)		BRCA - Breast invasive adenocarcinoma(625;0.0361)|LUSC - Lung squamous cell carcinoma(625;0.2)		ATTTGTAGGGCTTCTCTCCAG	0.403000													5	130					0	0	1	0	0	
OR51B5	282763	broad.mit.edu	37	11	5364380	5364381	+	Nonsense_Mutation	DNP	GC	TT	TT			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr11:5364380_5364381GC>TT	uc001map.1	-	1	374_375	c.374_375GC>AA	c.(373-375)TGC>TAA	p.C125*	HBG2_uc001mak.1_Intron|HBE1_uc001mam.1_Intron|OR51B5_uc001maq.1_Nonsense_Mutation_p.C125*	NM_001005567	NP_001005567	Q9H339	O51B5_HUMAN	olfactory receptor, family 51, subfamily B,	125	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			skin(1)	1		Medulloblastoma(188;0.0075)|all_neural(188;0.0572)|Breast(177;0.0675)		Epithelial(150;3.05e-09)|BRCA - Breast invasive adenocarcinoma(625;0.135)		TAAGAGGGTTGCAGATGGCAAT	0.470000													17	32					0	0	1	0	0	
CD82	3732	broad.mit.edu	37	11	44626715	44626715	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr11:44626715C>T	uc001myc.2	+	5	492	c.244C>T	c.(244-246)CGC>TGC	p.R82C	CD82_uc001myd.2_Missense_Mutation_p.R82C	NM_002231	NP_002222	P27701	CD82_HUMAN	CD82 antigen isoform 1	82	Cytoplasmic (Potential).					integral to plasma membrane	protein binding			ovary(1)	1						CAACGAGGTCCGCTGCCTGCT	0.652000													13	36					0	0	1	0	0	
RSF1	51773	broad.mit.edu	37	11	77412319	77412319	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr11:77412319C>T	uc001oyn.2	-	6	2075	c.1955G>A	c.(1954-1956)AGT>AAT	p.S652N	RSF1_uc001oym.2_Missense_Mutation_p.S400N	NM_016578	NP_057662	Q96T23	RSF1_HUMAN	remodeling and spacing factor 1	652					CenH3-containing nucleosome assembly at centromere|negative regulation of DNA binding|negative regulation of transcription, DNA-dependent|nucleosome positioning|positive regulation of transcription, DNA-dependent|positive regulation of viral transcription|transcription initiation, DNA-dependent	RSF complex	histone binding|protein binding|zinc ion binding			ovary(2)|central_nervous_system(2)	4	all_cancers(14;1.54e-17)|all_epithelial(13;4.06e-20)|Ovarian(111;0.152)		Epithelial(5;3e-50)|all cancers(3;6.37e-47)|BRCA - Breast invasive adenocarcinoma(5;9.82e-31)			AGTACTTGTACTCTGGCATTC	0.428000													76	37					0	0	1	0	0	
GRIA4	2893	broad.mit.edu	37	11	105732912	105732912	+	Missense_Mutation	SNP	G	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr11:105732912G>C	uc001pix.2	+	5	1096	c.650G>C	c.(649-651)AGA>ACA	p.R217T	GRIA4_uc001piu.1_Missense_Mutation_p.R217T|GRIA4_uc001piw.2_Missense_Mutation_p.R217T|GRIA4_uc001piv.2_Missense_Mutation_p.R217T|GRIA4_uc009yxk.1_Missense_Mutation_p.R217T	NM_000829	NP_000820	P48058	GRIA4_HUMAN	glutamate receptor, ionotrophic, AMPA 4 isoform	217	Extracellular (Potential).				glutamate signaling pathway|synaptic transmission	cell junction|endocytic vesicle membrane|integral to membrane|postsynaptic membrane	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|extracellular-glutamate-gated ion channel activity			ovary(3)|skin(3)|lung(1)|central_nervous_system(1)	8		Melanoma(852;0.000902)|Acute lymphoblastic leukemia(157;0.000994)|all_hematologic(158;0.0017)|Breast(348;0.0323)		BRCA - Breast invasive adenocarcinoma(274;0.000147)|Epithelial(105;0.0291)|all cancers(92;0.0899)	L-Glutamic Acid(DB00142)	GAGATAGAGAGACTTCAAAAC	0.328000													9	2					0	0	1	0	0	
TNFRSF1A	7132	broad.mit.edu	37	12	6440068	6440068	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:6440068C>T	uc001qnu.2	-	6	857	c.576G>A	c.(574-576)ACG>ACA	p.T192T	TNFRSF1A_uc001qnt.2_Silent_p.T84T|TNFRSF1A_uc010sey.1_5'UTR|TNFRSF1A_uc010sez.1_Silent_p.T84T|TNFRSF1A_uc009zek.2_Silent_p.T149T	NM_001065	NP_001056	P19438	TNR1A_HUMAN	tumor necrosis factor receptor 1 precursor	192	TNFR-Cys 4.|Extracellular (Potential).				apoptosis|cellular response to mechanical stimulus|induction of apoptosis by extracellular signals|inflammatory response|interspecies interaction between organisms|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of inflammatory response|positive regulation of transcription from RNA polymerase II promoter|prostaglandin metabolic process	extracellular region|integral to plasma membrane|membrane raft	tumor necrosis factor receptor activity			lung(2)|skin(1)	3						GGCACAACTTCGTGCACTCCA	0.507000													7	8					0	0	1	0	0	
SOX5	6660	broad.mit.edu	37	12	23793813	23793813	+	Missense_Mutation	SNP	T	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:23793813T>A	uc001rfw.2	-	8	1052	c.950A>T	c.(949-951)CAG>CTG	p.Q317L	SOX5_uc001rfx.2_Missense_Mutation_p.Q304L|SOX5_uc001rfy.2_Missense_Mutation_p.Q304L|SOX5_uc010siv.1_Missense_Mutation_p.Q304L|SOX5_uc010siw.1_RNA|SOX5_uc001rfz.1_Missense_Mutation_p.Q269L	NM_006940	NP_008871	P35711	SOX5_HUMAN	SRY (sex determining region Y)-box 5 isoform a	317					transcription from RNA polymerase II promoter	nucleus	DNA binding|protein binding|sequence-specific DNA binding transcription factor activity			ovary(5)|lung(1)	6						TGGGATCAGCTGAACAGGGTA	0.483000													49	51					0	0	1	0	0	
TUBA1A	7846	broad.mit.edu	37	12	49579682	49579682	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:49579682C>T	uc009zlf.2	-	4	739	c.467G>A	c.(466-468)CGT>CAT	p.R156H	TUBA1B_uc001rto.2_Intron|TUBA1A_uc001rtp.2_Missense_Mutation_p.R156H|TUBA1A_uc001rtq.2_Missense_Mutation_p.R3H|TUBA1A_uc001rtr.2_Missense_Mutation_p.R3H|TUBA1A_uc009zlg.2_Missense_Mutation_p.R3H	NM_006009	NP_006000	Q71U36	TBA1A_HUMAN	tubulin, alpha 1a	156					'de novo' posttranslational protein folding|G2/M transition of mitotic cell cycle|microtubule-based movement|protein polymerization	cytosol|microtubule	GTP binding|GTPase activity|structural molecule activity				0						AACTGAGAGACGTTCCATGAG	0.537000													10	20					0	0	1	0	0	
NEUROD4	58158	broad.mit.edu	37	12	55421022	55421022	+	Nonsense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:55421022C>T	uc001sgp.3	+	2	1177	c.799C>T	c.(799-801)CAA>TAA	p.Q267*		NM_021191	NP_067014	Q9HD90	NDF4_HUMAN	neurogenic differentiation 4	267					amacrine cell differentiation|positive regulation of cell differentiation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding			ovary(3)|skin(1)	4						CTCCTTGAAGCAAGATGGGTC	0.512000													33	64					0	0	1	0	0	
GLS2	27165	broad.mit.edu	37	12	56874168	56874168	+	Silent	SNP	A	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:56874168A>G	uc001slj.2	-	2	465	c.186T>C	c.(184-186)GAT>GAC	p.D62D	GLS2_uc009zos.2_RNA|GLS2_uc001slk.2_5'UTR|GLS2_uc009zot.2_5'UTR	NM_013267	NP_037399	Q9UI32	GLSL_HUMAN	glutaminase 2 precursor	62					cellular amino acid biosynthetic process|glutamate secretion|glutamine metabolic process|neurotransmitter secretion	mitochondrial matrix	glutaminase activity|protein binding			ovary(1)|central_nervous_system(1)	2					L-Glutamic Acid(DB00142)|L-Glutamine(DB00130)	TTTCTGATGAATCACTGTTTG	0.488000													28	38					0	0	1	0	0	
SRGAP1	57522	broad.mit.edu	37	12	64456870	64456870	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:64456870G>A	uc010ssp.1	+	7	1031	c.975G>A	c.(973-975)GCG>GCA	p.A325A	SRGAP1_uc001srt.2_Silent_p.A325A|SRGAP1_uc001srv.2_Silent_p.A285A	NM_020762	NP_065813	Q7Z6B7	SRGP1_HUMAN	SLIT-ROBO Rho GTPase activating protein 1	325					axon guidance	cytosol				ovary(2)|central_nervous_system(2)	4			GBM - Glioblastoma multiforme(3;0.000139)|BRCA - Breast invasive adenocarcinoma(9;0.225)	GBM - Glioblastoma multiforme(28;0.0608)		ACCCTGCTGCGTTCTGTCCAC	0.393000													11	91					0	0	1	0	0	
IL26	55801	broad.mit.edu	37	12	68618976	68618976	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:68618976G>A	uc001stx.1	-	3	351	c.316C>T	c.(316-318)CGC>TGC	p.R106C		NM_018402	NP_060872	Q9NPH9	IL26_HUMAN	interleukin 26 precursor	106					cell-cell signaling|negative regulation of epithelial cell proliferation|positive regulation of cytokine secretion|positive regulation of ERK1 and ERK2 cascade|positive regulation of JAK-STAT cascade|positive regulation of protein kinase B signaling cascade|positive regulation of stress-activated MAPK cascade|positive regulation of transcription from RNA polymerase II promoter	cytosol|extracellular space|soluble fraction	cytokine activity				0			Lung(24;0.000131)|LUAD - Lung adenocarcinoma(15;0.00107)|STAD - Stomach adenocarcinoma(21;0.018)	GBM - Glioblastoma multiforme(7;0.000515)		TCCACAAAGCGTATTTTCTTG	0.378000													24	50					0	0	1	0	0	
PLEKHG7	440107	broad.mit.edu	37	12	93135306	93135306	+	Missense_Mutation	SNP	A	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:93135306A>G	uc001tcj.2	+	4	369	c.139A>G	c.(139-141)AAG>GAG	p.K47E		NM_001004330	NP_001004330	Q6ZR37	PKHG7_HUMAN	pleckstrin homology domain containing, family G	47	DH.				regulation of Rho protein signal transduction	intracellular	Rho guanyl-nucleotide exchange factor activity			ovary(1)	1						TGGCATCATCAAGGACTATGT	0.418000													7	87					0	0	1	0	0	
PRDM4	11108	broad.mit.edu	37	12	108145867	108145867	+	Nonsense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr12:108145867G>A	uc001tmp.2	-	5	888	c.451C>T	c.(451-453)CAG>TAG	p.Q151*	PRDM4_uc001tmq.2_RNA	NM_012406	NP_036538	Q9UKN5	PRDM4_HUMAN	PR domain containing 4	151					cell proliferation|negative regulation of cell cycle|nerve growth factor receptor signaling pathway|regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter	nucleus	DNA binding|zinc ion binding			breast(1)|skin(1)	2						CCATTGGACTGATAGGGATCT	0.438000													51	103					0	0	1	0	0	
TRPC4	7223	broad.mit.edu	37	13	38357362	38357362	+	Missense_Mutation	SNP	A	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr13:38357362A>C	uc001uws.2	-	2	344	c.109T>G	c.(109-111)TTG>GTG	p.L37V	TRPC4_uc010abv.2_5'UTR|TRPC4_uc001uwt.2_Missense_Mutation_p.L37V|TRPC4_uc010tey.1_Missense_Mutation_p.L37V|TRPC4_uc010abw.2_Missense_Mutation_p.L37V|TRPC4_uc010abx.2_Missense_Mutation_p.L37V|TRPC4_uc010aby.2_Missense_Mutation_p.L37V	NM_016179	NP_057263	Q9UBN4	TRPC4_HUMAN	transient receptor potential cation channel,	37	Cytoplasmic (Potential).|ANK 1.				axon guidance|calcium ion import	basolateral plasma membrane|calcium channel complex|cell surface|cortical cytoskeleton	beta-catenin binding|cadherin binding|store-operated calcium channel activity			ovary(3)|skin(2)|breast(1)	6				all cancers(112;1.92e-08)|Epithelial(112;5.04e-06)|OV - Ovarian serous cystadenocarcinoma(117;0.000677)|GBM - Glioblastoma multiforme(144;0.00623)|BRCA - Breast invasive adenocarcinoma(63;0.0126)		ACAGCATTCAAGTAGGCTTTT	0.328000													42	105					0	0	1	0	0	
THSD1P1	374500	broad.mit.edu	37	13	52854029	52854029	+	RNA	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr13:52854029C>T	uc001vgm.1	-	6		c.497G>A								Homo sapiens cDNA FLJ14630 fis, clone NT2RP2000459.												0						AACGACATAGCGACAATATGT	0.308000													3	17					0	0	1	0	0	
OR11H12	440153	broad.mit.edu	37	14	19378556	19378556	+	Silent	SNP	A	G	G	rs144290036	by1000genomes	TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr14:19378556A>G	uc010tkp.1	+	1	963	c.963A>G	c.(961-963)GGA>GGG	p.G321G		NM_001013354	NP_001013372	B2RN74	O11HC_HUMAN	olfactory receptor, family 11, subfamily H,	321	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)	2	all_cancers(95;0.00108)		Epithelial(56;9.96e-07)|all cancers(55;2.95e-06)	GBM - Glioblastoma multiforme(265;0.00327)		AAGTTCTGGGAAGTTCCAACA	0.363000													4	23					0	0	1	0	0	
DYNC1H1	1778	broad.mit.edu	37	14	102516478	102516478	+	Silent	SNP	T	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr14:102516478T>C	uc001yks.2	+	77	13919	c.13755T>C	c.(13753-13755)CTT>CTC	p.L4585L		NM_001376	NP_001367	Q14204	DYHC1_HUMAN	cytoplasmic dynein 1 heavy chain 1	4585					cytoplasmic mRNA processing body assembly|G2/M transition of mitotic cell cycle|microtubule-based movement|mitotic spindle organization|stress granule assembly|transport	centrosome|cytoplasmic dynein complex|cytosol|Golgi apparatus|microtubule	ATP binding|ATPase activity, coupled|microtubule motor activity|protein binding			ovary(7)|central_nervous_system(2)|pancreas(1)	10						CAACCGCCCTTCCCCTGACGC	0.572000													3	44					0	0	1	0	0	
MTA1	9112	broad.mit.edu	37	14	105931130	105931130	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr14:105931130G>T	uc001yqx.2	+	15	1651	c.1464G>T	c.(1462-1464)GAG>GAT	p.E488D	MTA1_uc001yqy.2_RNA|MTA1_uc001yrb.2_Missense_Mutation_p.E249D	NM_004689	NP_004680	Q13330	MTA1_HUMAN	metastasis associated protein	488					signal transduction	cytoplasm|nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|central_nervous_system(1)	2		all_cancers(154;0.0293)|all_epithelial(191;0.128)|Melanoma(154;0.155)	OV - Ovarian serous cystadenocarcinoma(23;0.00897)|Epithelial(46;0.026)	Epithelial(152;0.19)		TGTGCCGTGAGATCCTGCGCC	0.667000													11	6					2.61681e-11	2.8254e-11	1	1	0	
MKRN3	7681	broad.mit.edu	37	15	23811866	23811866	+	Missense_Mutation	SNP	A	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr15:23811866A>T	uc001ywh.3	+	1	1413	c.937A>T	c.(937-939)ATC>TTC	p.I313F	MKRN3_uc001ywi.2_Intron|MKRN3_uc010ayi.1_Missense_Mutation_p.I313F	NM_005664	NP_005655	Q13064	MKRN3_HUMAN	makorin ring finger protein 3	313	RING-type.					ribonucleoprotein complex	ligase activity|nucleic acid binding|zinc ion binding			lung(6)|large_intestine(2)|ovary(2)	10		all_cancers(20;8.44e-25)|all_epithelial(15;3.69e-22)|Lung NSC(15;2.96e-18)|all_lung(15;2.8e-17)|Breast(32;0.000353)|Colorectal(260;0.14)		all cancers(64;3.02e-06)|Epithelial(43;1.94e-05)|BRCA - Breast invasive adenocarcinoma(123;0.0012)		GGTGTGTGGCATCTGCATGGA	0.502000													19	17					0	0	1	0	0	
WDR72	256764	broad.mit.edu	37	15	53992012	53992012	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr15:53992012G>A	uc002acj.2	-	13	1742	c.1700C>T	c.(1699-1701)CCG>CTG	p.P567L	WDR72_uc010bfi.1_Missense_Mutation_p.P567L	NM_182758	NP_877435	Q3MJ13	WDR72_HUMAN	WD repeat domain 72	567	WD 8.									lung(1)|skin(1)	2				all cancers(107;0.0511)		ATTCTCAACCGGGTGCCATTT	0.423000													30	112					0	0	1	0	0	
LBXCOR1	390598	broad.mit.edu	37	15	68118581	68118581	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr15:68118581C>T	uc002aqy.1	+	2	388	c.388C>T	c.(388-390)CGT>TGT	p.R130C		NM_001031807	NP_001026977	P84550	SKOR1_HUMAN	transcriptional corepressor Corl1	139					negative regulation of BMP signaling pathway|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transforming growth factor beta receptor signaling pathway|transcription, DNA-dependent	cytoplasm|dendrite|neuronal cell body|nucleus	nucleotide binding|SMAD binding|transcription repressor activity				0						GGAGATTCTGCGTCGGGCCGG	0.632000													9	27					0	0	1	0	0	
CYP1A2	1544	broad.mit.edu	37	15	75042262	75042262	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr15:75042262G>A	uc002ayr.1	+	2	247	c.183G>A	c.(181-183)CCG>CCA	p.P61P		NM_000761	NP_000752	P05177	CP1A2_HUMAN	cytochrome P450, family 1, subfamily A,	61					alkaloid metabolic process|exogenous drug catabolic process|methylation|monocarboxylic acid metabolic process|monoterpenoid metabolic process|oxidative deethylation|oxidative demethylation|steroid catabolic process|toxin biosynthetic process|xenobiotic metabolic process	endoplasmic reticulum membrane|microsome	aromatase activity|caffeine oxidase activity|demethylase activity|electron carrier activity|enzyme binding|heme binding|oxygen binding			ovary(3)|breast(1)	4					Acenocoumarol(DB01418)|Acetaminophen(DB00316)|Aciclovir(DB00787)|Alosetron(DB00969)|Aminophenazone(DB01424)|Amitriptyline(DB00321)|Anagrelide(DB00261)|Azelastine(DB00972)|Bortezomib(DB00188)|Caffeine(DB00201)|Carmustine(DB00262)|Chlordiazepoxide(DB00475)|Chlorpromazine(DB00477)|Chlorzoxazone(DB00356)|Cimetidine(DB00501)|Cinacalcet(DB01012)|Ciprofloxacin(DB00537)|Clomipramine(DB01242)|Clotrimazole(DB00257)|Clozapine(DB00363)|Conjugated Estrogens(DB00286)|Cyclobenzaprine(DB00924)|Dacarbazine(DB00851)|Desloratadine(DB00967)|Diazepam(DB00829)|Dibucaine(DB00527)|Diclofenac(DB00586)|Duloxetine(DB00476)|Enoxacin(DB00467)|Esomeprazole(DB00736)|Estradiol(DB00783)|Estrone(DB00655)|Fluorouracil(DB00544)|Flutamide(DB00499)|Fluvoxamine(DB00176)|Frovatriptan(DB00998)|Grepafloxacin(DB00365)|Haloperidol(DB00502)|Hesperetin(DB01094)|Imipramine(DB00458)|Ketoconazole(DB01026)|Leflunomide(DB01097)|Levobupivacaine(DB01002)|Levofloxacin(DB01137)|Lidocaine(DB00281)|Lomefloxacin(DB00978)|Melatonin(DB01065)|Mephenytoin(DB00532)|Mexiletine(DB00379)|Mirtazapine(DB00370)|Norfloxacin(DB01059)|Nortriptyline(DB00540)|Ofloxacin(DB01165)|Olanzapine(DB00334)|Ondansetron(DB00904)|Palonosetron(DB00377)|Pantoprazole(DB00213)|Pefloxacin(DB00487)|Pimozide(DB01100)|Propafenone(DB01182)|Propranolol(DB00571)|Quinidine(DB00908)|Ramelteon(DB00980)|Ranitidine(DB00863)|Rasagiline(DB01367)|Rifampin(DB01045)|Riluzole(DB00740)|Rofecoxib(DB00533)|Ropinirole(DB00268)|Ropivacaine(DB00296)|Tacrine(DB00382)|Telithromycin(DB00976)|Terfenadine(DB00342)|Theophylline(DB00277)|Thiabendazole(DB00730)|Tizanidine(DB00697)|Tolbutamide(DB01124)|Verapamil(DB00661)|Warfarin(DB00682)|Zileuton(DB00744)|Zolmitriptan(DB00315)	GGAAGAACCCGCACCTGGCAC	0.647000													14	35					0	0	1	0	0	
ACAN	176	broad.mit.edu	37	15	89402387	89402387	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr15:89402387G>A	uc010upo.1	+	12	6945	c.6571G>A	c.(6571-6573)GCT>ACT	p.A2191T	ACAN_uc010upp.1_Missense_Mutation_p.A2191T|ACAN_uc002bna.2_RNA	NM_013227	NP_037359	E7EX88	E7EX88_HUMAN	aggrecan isoform 2 precursor	2191					cell adhesion		hyaluronic acid binding|sugar binding			ovary(2)|central_nervous_system(1)	3	Lung NSC(78;0.0392)|all_lung(78;0.077)		BRCA - Breast invasive adenocarcinoma(143;0.146)			CACTCCCACGGCTTCTGGAGA	0.607000													24	73					0	0	1	0	0	
TSC2	7249	broad.mit.edu	37	16	2134515	2134515	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:2134515C>T	uc002con.2	+	34	4398	c.4292C>T	c.(4291-4293)TCG>TTG	p.S1431L	TSC2_uc010bsd.2_Missense_Mutation_p.S1408L|TSC2_uc002coo.2_Missense_Mutation_p.S1364L|TSC2_uc010uvv.1_Missense_Mutation_p.S1328L|TSC2_uc010uvw.1_Missense_Mutation_p.S1316L|TSC2_uc002cop.2_Missense_Mutation_p.S1187L|TSC2_uc002coq.2_Missense_Mutation_p.S206L|TSC2_uc002cor.2_Missense_Mutation_p.S132L	NM_000548	NP_000539	P49815	TSC2_HUMAN	tuberous sclerosis 2 isoform 1	1431					cell cycle arrest|endocytosis|heart development|insulin receptor signaling pathway|insulin-like growth factor receptor signaling pathway|negative regulation of cell size|negative regulation of phosphatidylinositol 3-kinase cascade|negative regulation of protein kinase B signaling cascade|negative regulation of TOR signaling cascade|negative regulation of Wnt receptor signaling pathway|nerve growth factor receptor signaling pathway|neural tube closure|phosphatidylinositol-mediated signaling|positive chemotaxis|protein import into nucleus|protein kinase B signaling cascade|regulation of endocytosis|regulation of insulin receptor signaling pathway|regulation of small GTPase mediated signal transduction	Golgi apparatus|nucleus|perinuclear region of cytoplasm|TSC1-TSC2 complex	GTPase activator activity|protein homodimerization activity			central_nervous_system(4)|lung(3)|ovary(2)|pancreas(1)	10		Hepatocellular(780;0.0202)				GCTGCCTGGTCGGCCTCGGGC	0.711000			D|Mis|N|F|S			hamartoma|renal cell			Tuberous_Sclerosis				3	4					0	0	1	0	0	
TAOK2	9344	broad.mit.edu	37	16	29994174	29994174	+	Missense_Mutation	SNP	C	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:29994174C>A	uc002dva.1	+	11	1734	c.951C>A	c.(949-951)TTC>TTA	p.F317L	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|TAOK2_uc002dvb.1_Missense_Mutation_p.F317L|TAOK2_uc002dvc.1_Missense_Mutation_p.F317L|TAOK2_uc010bzm.1_Missense_Mutation_p.F317L|TAOK2_uc002dvd.1_Missense_Mutation_p.F144L	NM_016151	NP_057235	Q9UL54	TAOK2_HUMAN	TAO kinase 2 isoform 2	317					actin cytoskeleton organization|activation of MAPKK activity|apoptosis|cell migration|focal adhesion assembly|positive regulation of JNK cascade|protein targeting to membrane|regulation of cell growth|regulation of cell shape|response to stress	cytoplasmic vesicle membrane|cytoskeleton|dendrite|integral to membrane|nucleolus	ATP binding|protein serine/threonine kinase activity			ovary(1)	1						AGATCCTGTTCCAAGAGGCAC	0.607000													22	136					4.7796e-09	5.08686e-09	1	1	0	
CORO1A	11151	broad.mit.edu	37	16	30198029	30198029	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:30198029C>T	uc002dww.2	+	3	431	c.309C>T	c.(307-309)GAC>GAT	p.D103D	uc002dtf.2_Intron|BOLA2_uc010bzb.1_Intron|CORO1A_uc010vej.1_Silent_p.D103D|CORO1A_uc010bzq.2_Silent_p.D103D|CORO1A_uc010bzr.2_Silent_p.D103D|CORO1A_uc002dwx.2_5'UTR|CORO1A_uc002dwy.1_5'UTR|LOC606724_uc002dwz.1_5'Flank	NM_007074	NP_009005	P31146	COR1A_HUMAN	coronin, actin binding protein, 1A	103	WD 2.				cell-substrate adhesion|innate immune response|leukocyte chemotaxis|negative regulation of actin nucleation|phagolysosome assembly|positive chemotaxis|regulation of cell shape|uropod organization	actin filament|cortical actin cytoskeleton|lamellipodium|phagocytic cup|phagocytic vesicle membrane	actin filament binding|phosphatidylinositol 3-kinase binding|protein C-terminus binding|protein homodimerization activity				0						GCTCCGAGGACTGCACAGTCA	0.612000													6	24					0	0	1	0	0	
ZNF689	115509	broad.mit.edu	37	16	30615983	30615983	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:30615983C>T	uc002dyx.2	-	3	1425	c.1105G>A	c.(1105-1107)GGA>AGA	p.G369R	ZNF689_uc010bzy.2_Silent_p.P24P	NM_138447	NP_612456	Q96CS4	ZN689_HUMAN	zinc finger protein HIT-39	369					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0			Colorectal(24;0.198)			GGCTTCTCTCCGGTGTGCAAG	0.682000													6	36					0	0	1	0	0	
UBE2MP1	606551	broad.mit.edu	37	16	34404281	34404281	+	RNA	SNP	G	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:34404281G>C	uc002edv.1	-	1		c.482C>G				NR_002837				full-length cDNA clone CS0DH003YB23 of T cells (Jurkat cell line) of Homo sapiens (human).												0						GGATGTTGAGGCAGACGTTGC	0.512000													8	21					0	0	1	0	0	
CDH11	1009	broad.mit.edu	37	16	65016158	65016158	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:65016158G>T	uc002eoi.2	-	8	1480	c.1046C>A	c.(1045-1047)GCA>GAA	p.A349E	CDH11_uc010cdn.2_Intron|CDH11_uc002eoj.2_Missense_Mutation_p.A349E|CDH11_uc010vin.1_Missense_Mutation_p.A223E|CDH11_uc002eok.1_RNA	NM_001797	NP_001788	P55287	CAD11_HUMAN	cadherin 11, type 2 preproprotein	349	Cadherin 3.|Extracellular (Potential).				adherens junction organization|cell junction assembly|homophilic cell adhesion|ossification|skeletal system development	integral to membrane|plasma membrane	calcium ion binding|protein binding			lung(10)|ovary(3)|skin(1)	14		Ovarian(137;0.0973)		OV - Ovarian serous cystadenocarcinoma(108;0.205)		CACGTTGGCTGCCTCTACCTT	0.453000			T	USP6	aneurysmal bone cysts					TSP Lung(24;0.17)			15	20					1.67942e-08	1.7747e-08	1	1	0	
WDR59	79726	broad.mit.edu	37	16	74943527	74943527	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:74943527G>A	uc002fdh.1	-	16	1616	c.1514C>T	c.(1513-1515)CCG>CTG	p.P505L	WDR59_uc002fdi.2_Missense_Mutation_p.P505L|WDR59_uc002fdg.1_Missense_Mutation_p.P97L	NM_030581	NP_085058	Q6PJI9	WDR59_HUMAN	WD repeat domain 59	505										ovary(1)|breast(1)	2						GAGTGCAAACGGGTTGCTGGA	0.502000													51	61					0	0	1	0	0	
C16orf3	750	broad.mit.edu	37	16	90095731	90095731	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr16:90095731G>A	uc002fqk.1	-	1	579	c.20C>T	c.(19-21)GCG>GTG	p.A7V	GAS8_uc010vps.1_Intron|GAS8_uc002fqh.2_Intron|GAS8_uc010vpt.1_Intron|GAS8_uc010vpu.1_Intron|GAS8_uc010vpv.1_Intron|GAS8_uc010cjc.1_Intron|GAS8_uc002fqi.1_Intron|GAS8_uc010vpw.1_Intron|GAS8_uc002fqj.1_Intron	NM_001214	NP_001205	O95177	CP003_HUMAN	hypothetical protein LOC750	7											0		all_cancers(9;9.01e-08)|Hepatocellular(780;0.000325)|Lung NSC(15;0.0104)|all_lung(18;0.0239)		BRCA - Breast invasive adenocarcinoma(80;0.0272)		ctcctgccccgcagcagagga	0.184000													21	57					0	0	1	0	0	
RAP1GAP2	23108	broad.mit.edu	37	17	2934234	2934234	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr17:2934234C>T	uc010ckd.2	+	23	2216	c.2126C>T	c.(2125-2127)TCC>TTC	p.S709F	RAP1GAP2_uc010cke.2_Missense_Mutation_p.S694F	NM_015085	NP_055900	Q684P5	RPGP2_HUMAN	RAP1 GTPase activating protein 2 isoform 1	709	Ser-rich.				regulation of small GTPase mediated signal transduction	centrosome|cytosol|perinuclear region of cytoplasm	GTPase activator activity			ovary(1)	1						AGCAGAAACTCCCCGAGATCG	0.572000													3	6					0	0	1	0	0	
TP53	7157	broad.mit.edu	37	17	7574003	7574003	+	Nonsense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr17:7574003G>A	uc002gim.2	-	10	1218	c.1024C>T	c.(1024-1026)CGA>TGA	p.R342*	TP53_uc002gig.1_Intron|TP53_uc002gih.2_Intron|TP53_uc010cne.1_Intron|TP53_uc010cnf.1_3'UTR|TP53_uc010cng.1_3'UTR|TP53_uc002gii.1_Nonsense_Mutation_p.R210*|TP53_uc010cnh.1_3'UTR|TP53_uc010cni.1_3'UTR|TP53_uc002gij.2_Nonsense_Mutation_p.R342*	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	342	Oligomerization.|Interaction with HIPK1 (By similarity).|Interaction with CARM1.|Nuclear export signal.|Interaction with HIPK2.		R -> P (in sporadic cancers; somatic mutation).|R -> Q (in sporadic cancers; somatic mutation).|R -> L (in a sporadic cancer; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.R342*(49)|p.0?(7)|p.R342fs*3(5)|p.R342P(3)|p.R342Q(2)|p.?(1)|p.R342_N345delRELN(1)|p.I332fs*5(1)		large_intestine(4656)|breast(2429)|upper_aerodigestive_tract(2212)|lung(2028)|ovary(1592)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1228)|stomach(1136)|urinary_tract(1114)|central_nervous_system(1085)|liver(805)|skin(694)|pancreas(375)|biliary_tract(247)|soft_tissue(209)|prostate(194)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(43)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	22245		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		TTCAGCTCTCGGAACATCTCG	0.498000		111	Mis|N|F		breast|colorectal|lung|sarcoma|adrenocortical|glioma|multiple other tumour types	breast|sarcoma|adrenocortical carcinoma|glioma|multiple other tumour types		Other_conserved_DNA_damage_response_genes	Hereditary_Adrenocortical_Cancer|Endometrial_Cancer_Familial_Clustering_of|Hereditary_Breast-Ovarian_Cancer_non-BRCA1/2|Li-Fraumeni_syndrome|Osteosarcoma_Familial_Clustering_of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			19	5					0	0	1	0	0	
Unknown	0	broad.mit.edu	37	17	21730847	21730847	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr17:21730847G>T	uc002gyy.3	+	2	274	c.149G>T	c.(148-150)CGG>CTG	p.R50L						SubName: Full=cDNA FLJ51326, highly similar to Homo sapiens ubiquitin B (UBB), mRNA;																		GGCAAGCAGCGGGAAGATGGC	0.522000													4	21					0.00909568	0.00909568	1	1	0	
C17orf42	79736	broad.mit.edu	37	17	29226358	29226358	+	Silent	SNP	G	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr17:29226358G>C	uc002hfu.2	-	4	982	c.912C>G	c.(910-912)CTC>CTG	p.L304L	C17orf42_uc002hfv.2_RNA	NM_024683	NP_078959	Q96QE5	TEFM_HUMAN	hypothetical protein LOC79736	304					oxidative phosphorylation|regulation of transcription, DNA-dependent|transcription from mitochondrial promoter	mitochondrial nucleoid|ribonucleoprotein complex	DNA polymerase processivity factor activity|nucleic acid binding|protein binding			ovary(1)	1		all_cancers(10;4.64e-07)|all_hematologic(16;0.014)|Acute lymphoblastic leukemia(14;0.0236)|Myeloproliferative disorder(56;0.0255)				TAGAATCGAAGAGAAACTGCT	0.428000													21	51					0	0	1	0	0	
KRT23	25984	broad.mit.edu	37	17	39081631	39081631	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr17:39081631G>A	uc002hvm.1	-	7	1706	c.1117C>T	c.(1117-1119)CGG>TGG	p.R373W	KRT23_uc010wfl.1_Missense_Mutation_p.R236W|KRT23_uc010cxf.1_Missense_Mutation_p.R160W|KRT23_uc010cxg.2_Missense_Mutation_p.R373W	NM_015515	NP_056330	Q9C075	K1C23_HUMAN	keratin 23	373	Rod.|Coil 2.					intermediate filament	structural molecule activity			ovary(1)	1		Breast(137;0.000301)|Ovarian(249;0.15)				TCCAGGAGCCGTCGGTACGTG	0.562000													36	399					0	0	1	0	0	
KRT40	125115	broad.mit.edu	37	17	39135121	39135121	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr17:39135121G>A	uc010cxh.1	-	8	1292	c.1131C>T	c.(1129-1131)GAC>GAT	p.D377D	KRT40_uc002hvq.1_RNA	NM_182497	NP_872303	Q6A162	K1C40_HUMAN	type I hair keratin KA36	377	Rod.|Coil 2.					intermediate filament	structural molecule activity				0		Breast(137;0.00043)				GGGCCTTCACGTCCAGGAGCA	0.587000													35	372					0	0	1	0	0	
HEATR6	63897	broad.mit.edu	37	17	58134504	58134504	+	Missense_Mutation	SNP	C	T	T	rs147472962	byFrequency	TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr17:58134504C>T	uc002iyk.1	-	12	2001	c.1984G>A	c.(1984-1986)GTA>ATA	p.V662I	HEATR6_uc010ddk.1_Missense_Mutation_p.V201I|HEATR6_uc010wos.1_Missense_Mutation_p.V494I	NM_022070	NP_071353	Q6AI08	HEAT6_HUMAN	HEAT repeat containing 6	662							binding			ovary(1)|skin(1)	2	all_cancers(5;2.25e-13)|Breast(5;4.84e-25)|all_neural(34;0.0878)|Medulloblastoma(34;0.0922)		BRCA - Breast invasive adenocarcinoma(1;5.93e-19)|Epithelial(12;7.59e-12)|all cancers(12;1.26e-10)			TTGGGCAGTACGACAATGGAA	0.557000													22	81					0	0	1	0	0	
PTPRM	5797	broad.mit.edu	37	18	8376491	8376491	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr18:8376491G>A	uc002knn.3	+	24	3822	c.3319G>A	c.(3319-3321)GTC>ATC	p.V1107I	PTPRM_uc010dkv.2_Missense_Mutation_p.V1120I|PTPRM_uc010wzl.1_Missense_Mutation_p.V894I	NM_002845	NP_002836	P28827	PTPRM_HUMAN	protein tyrosine phosphatase, receptor type, M	1107	Tyrosine-protein phosphatase 1.|Cytoplasmic (Potential).				homophilic cell adhesion|negative regulation of angiogenesis|negative regulation of endothelial cell migration|negative regulation of endothelial cell proliferation|response to drug|retina layer formation|retinal ganglion cell axon guidance	cell-cell adherens junction|integral to plasma membrane|lamellipodium|perinuclear region of cytoplasm	cadherin binding|transmembrane receptor protein tyrosine phosphatase activity			lung(3)|ovary(2)|central_nervous_system(1)	6		Colorectal(10;0.234)				CTGTTTCATCGTCATTGATAT	0.517000													47	60					0	0	1	0	0	
CIDEA	1149	broad.mit.edu	37	18	12274118	12274118	+	Silent	SNP	G	A	A	rs140727009	byFrequency	TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr18:12274118G>A	uc002kqt.3	+	4	422	c.357G>A	c.(355-357)TCG>TCA	p.S119S	CIDEA_uc002kqu.3_Silent_p.S153S|CIDEA_uc010dlc.2_RNA	NM_001279	NP_001270	O60543	CIDEA_HUMAN	cell death-inducing DFFA-like effector a isoform	119					DNA damage response, signal transduction resulting in induction of apoptosis|DNA fragmentation involved in apoptotic nuclear change|lipid metabolic process|lipid storage|negative regulation of apoptosis|negative regulation of cytokine secretion|negative regulation of lipid catabolic process|negative regulation of transforming growth factor beta receptor signaling pathway|negative regulation of tumor necrosis factor production|positive regulation of sequestering of triglyceride|temperature homeostasis	mitochondrial envelope|nucleus	protein homodimerization activity			ovary(1)|central_nervous_system(1)	2						CCACTTGCTCGCCGCCGAAGA	0.592000													28	31					0	0	1	0	0	
TMPRSS9	360200	broad.mit.edu	37	19	2403177	2403177	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:2403177C>T	uc010xgx.1	+	5	552	c.552C>T	c.(550-552)TCC>TCT	p.S184S	TMPRSS9_uc002lvv.1_Silent_p.S218S	NM_182973	NP_892018	Q7Z410	TMPS9_HUMAN	transmembrane protease, serine 9	184	LDL-receptor class A.|Extracellular (Potential).				proteolysis	integral to plasma membrane	serine-type endopeptidase activity			ovary(1)|central_nervous_system(1)	2				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CCGATGGGTCCGACGAGGCGC	0.632000													6	5					0	0	1	0	0	
PLIN4	729359	broad.mit.edu	37	19	4512722	4512722	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:4512722G>A	uc002mar.1	-	3	1208	c.1208C>T	c.(1207-1209)GCC>GTC	p.A403V	PLIN4_uc010dub.1_5'Flank	NM_001080400	NP_001073869	Q96Q06	PLIN4_HUMAN	plasma membrane associated protein, S3-12	403	10.|27 X 33 AA approximate tandem repeat.					lipid particle|plasma membrane					0						AGTTTGCATGGCCCCCTTGGC	0.567000													4	81					0	0	1	0	0	
TICAM1	148022	broad.mit.edu	37	19	4817152	4817152	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:4817152C>T	uc002mbi.2	-	2	1489	c.1238G>A	c.(1237-1239)CGG>CAG	p.R413Q		NM_182919	NP_891549	Q8IUC6	TCAM1_HUMAN	toll-like receptor adaptor molecule 1	413	TIR.				apoptosis|I-kappaB kinase/NF-kappaB cascade|inflammatory response|innate immune response|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB cascade|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|endosome membrane|plasma membrane	protein kinase binding|signal transducer activity			breast(1)	1				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0139)		CAGCTTCTCCCGAACCCGCAG	0.617000													5	27					0	0	1	0	0	
ADAMTS10	81794	broad.mit.edu	37	19	8670208	8670208	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:8670208C>T	uc002mkj.1	-	4	398	c.124G>A	c.(124-126)GCC>ACC	p.A42T	ADAMTS10_uc002mkk.1_5'UTR	NM_030957	NP_112219	Q9H324	ATS10_HUMAN	ADAM metallopeptidase with thrombospondin type 1	42					proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			pancreas(2)|skin(2)	4						GTGGGGAAGGCGATCTCATAG	0.677000													3	7					0	0	1	0	0	
MUC16	94025	broad.mit.edu	37	19	9058711	9058711	+	Missense_Mutation	SNP	A	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:9058711A>T	uc002mkp.2	-	3	28939	c.28735T>A	c.(28735-28737)TCA>ACA	p.S9579T		NM_024690	NP_078966	Q8WXI7	MUC16_HUMAN	mucin 16	9581	Ser-rich.|Thr-rich.|Extracellular (Potential).				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			lung(30)|ovary(15)|breast(8)|large_intestine(1)|skin(1)|prostate(1)|pancreas(1)	57						GTCAGAGATGACATTGACTCT	0.502000													11	27					0	0	1	0	0	
OR7D2	162998	broad.mit.edu	37	19	9297245	9297245	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:9297245C>T	uc002mkz.1	+	1	976	c.788C>T	c.(787-789)GCG>GTG	p.A263V		NM_175883	NP_787079	Q96RA2	OR7D2_HUMAN	olfactory receptor, family 7, subfamily D,	263	Extracellular (Potential).				regulation of transcription, DNA-dependent|sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)|upper_aerodigestive_tract(1)	3						TTCACTTCTGCGGTGACTCAC	0.507000													26	68					0	0	1	0	0	
RAVER1	125950	broad.mit.edu	37	19	10434179	10434179	+	Missense_Mutation	SNP	T	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:10434179T>C	uc002moa.2	-	4	951	c.871A>G	c.(871-873)ATG>GTG	p.M291V		NM_133452	NP_597709	Q8IY67	RAVR1_HUMAN	RAVER1	274	RRM 3.					cytoplasm|nucleus	nucleotide binding|protein binding|RNA binding			ovary(1)	1			OV - Ovarian serous cystadenocarcinoma(20;1.81e-09)|Epithelial(33;3.65e-06)|all cancers(31;8.35e-06)			TCCTCCGCCATCTCAGCCGTC	0.697000													15	33					0	0	1	0	0	
ZNF99	7652	broad.mit.edu	37	19	22951157	22951157	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:22951157C>T	uc010xrh.1	-	3	239	c.239G>A	c.(238-240)GGG>GAG	p.G80E		NM_001080409	NP_001073878			zinc finger protein 99											ovary(1)|skin(1)	2		Lung NSC(12;0.0207)|all_lung(12;0.0214)|all_epithelial(12;0.102)				AGGCTCTTTCCCTTGCTTCAG	0.363000													7	15					0	0	1	0	0	
FPR3	2359	broad.mit.edu	37	19	52327921	52327921	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:52327921G>A	uc002pxt.1	+	2	1104	c.920G>A	c.(919-921)CGT>CAT	p.R307H		NM_002030	NP_002021	P25089	FPR3_HUMAN	formyl peptide receptor-like 2	307	Cytoplasmic (Potential).				cellular component movement|chemotaxis	integral to membrane|plasma membrane	N-formyl peptide receptor activity			lung(4)|breast(1)|skin(1)	6						TTTATGGGTCGTAACTTCCAA	0.473000													47	86					0	0	1	0	0	
ZNF813	126017	broad.mit.edu	37	19	53994528	53994528	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:53994528C>T	uc002qbu.2	+	4	1170	c.1042C>T	c.(1042-1044)CTT>TTT	p.L348F	ZNF813_uc010eqq.1_Intron	NM_001004301	NP_001004301	Q6ZN06	ZN813_HUMAN	zinc finger protein 813	348	C2H2-type 5.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(1)	1				GBM - Glioblastoma multiforme(134;0.00619)		CCATCGTAGACTTCATACTGG	0.418000													12	191					0	0	1	0	0	
ZNF813	126017	broad.mit.edu	37	19	53994690	53994690	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:53994690C>T	uc002qbu.2	+	4	1332	c.1204C>T	c.(1204-1206)CGT>TGT	p.R402C	ZNF813_uc010eqq.1_Intron	NM_001004301	NP_001004301	Q6ZN06	ZN813_HUMAN	zinc finger protein 813	402	C2H2-type 7.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(1)	1				GBM - Glioblastoma multiforme(134;0.00619)		TAAATGCCATCGTAGACTTCA	0.408000													10	36					0	0	1	0	0	
ZNF471	57573	broad.mit.edu	37	19	57036448	57036448	+	Nonsense_Mutation	SNP	A	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:57036448A>T	uc002qnh.2	+	5	1145	c.1012A>T	c.(1012-1014)AGA>TGA	p.R338*		NM_020813	NP_065864	Q9BX82	ZN471_HUMAN	zinc finger protein 471	338	C2H2-type 5.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(1)|ovary(1)	2		Colorectal(82;5.46e-05)|Ovarian(87;0.0822)|Renal(1328;0.157)		GBM - Glioblastoma multiforme(193;0.0307)		TCGACATCAGAGATGTCACAC	0.428000													12	33					0	0	1	0	0	
ZNF418	147686	broad.mit.edu	37	19	58439318	58439318	+	Silent	SNP	A	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:58439318A>T	uc002qqs.1	-	4	523	c.231T>A	c.(229-231)TCT>TCA	p.S77S	ZNF418_uc010yhn.1_RNA|ZNF418_uc010yho.1_5'UTR	NM_133460	NP_597717	Q8TF45	ZN418_HUMAN	zinc finger protein 418	77	KRAB.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Colorectal(82;0.000256)|all_neural(62;0.0577)|Breast(46;0.147)|Ovarian(87;0.156)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0158)		CCTTCTTGGGAGACACACCTG	0.502000													18	40					0	0	1	0	0	
ZNF606	80095	broad.mit.edu	37	19	58489952	58489952	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:58489952C>T	uc002qqw.2	-	7	2714	c.2096G>A	c.(2095-2097)CGG>CAG	p.R699Q	ZNF606_uc010yhp.1_Missense_Mutation_p.R609Q	NM_025027	NP_079303	Q8WXB4	ZN606_HUMAN	zinc finger protein 606	699	C2H2-type 13.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			upper_aerodigestive_tract(1)|ovary(1)	2		Colorectal(82;5.46e-05)|all_neural(62;0.0182)|Breast(46;0.0389)|Ovarian(87;0.0443)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0168)		ATGAGTTCTCCGGTGTGCAAT	0.408000													16	50					0	0	1	0	0	
PXDN	7837	broad.mit.edu	37	2	1653281	1653281	+	Silent	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:1653281G>T	uc002qxa.2	-	17	2335	c.2271C>A	c.(2269-2271)GGC>GGA	p.G757G		NM_012293	NP_036425	Q92626	PXDN_HUMAN	peroxidasin precursor	757					extracellular matrix organization|hydrogen peroxide catabolic process|immune response	endoplasmic reticulum|extracellular space|proteinaceous extracellular matrix	extracellular matrix structural constituent|heme binding|interleukin-1 receptor antagonist activity|peroxidase activity			pancreas(6)|ovary(2)	8	Acute lymphoblastic leukemia(172;0.0627)|all_hematologic(175;0.0797)	all_cancers(51;0.0845)|Lung NSC(108;0.00641)|all_epithelial(98;0.00716)		all cancers(51;0.0492)|OV - Ovarian serous cystadenocarcinoma(76;0.0973)|Epithelial(75;0.17)|GBM - Glioblastoma multiforme(21;0.228)		TCAGCGAGGCGCCCCACATGG	0.637000													46	87					6.9144e-35	7.6884e-35	1	1	0	
OTOF	9381	broad.mit.edu	37	2	26712165	26712165	+	Splice_Site	SNP	T	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:26712165T>G	uc002rhk.2	-	11	1088	c.961_splice	c.e11-1	p.V321_splice		NM_194248	NP_919224	Q9HC10	OTOF_HUMAN	otoferlin isoform a						cellular membrane fusion|sensory perception of sound|synaptic vesicle exocytosis	basolateral plasma membrane|cell junction|cytosol|endoplasmic reticulum membrane|integral to membrane|membrane fraction|synaptic vesicle membrane	calcium ion binding			ovary(3)|breast(2)|central_nervous_system(1)|pancreas(1)	7	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					GTGAATCACCTTTCAGGCAGA	0.612000													6	15					0	0	1	0	0	
ZFP36L2	678	broad.mit.edu	37	2	43452440	43452440	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:43452440C>T	uc002rsv.3	-	2	794	c.503G>A	c.(502-504)TGC>TAC	p.C168Y	LOC100129726_uc010ynx.1_5'Flank	NM_006887	NP_008818	P47974	TISD_HUMAN	zinc finger protein 36, C3H type-like 2	168	C3H1-type 1.				cell proliferation	nucleus	DNA binding|RNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding				0		Acute lymphoblastic leukemia(82;0.00323)|all_hematologic(82;0.00824)				GCCGTACTTGCACGTGCCGCT	0.637000													12	22					0	0	1	0	0	
TSN	7247	broad.mit.edu	37	2	122519067	122519067	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:122519067G>A	uc002tnl.2	+	4	575	c.340G>A	c.(340-342)GTG>ATG	p.V114M	TSN_uc002tnm.2_Missense_Mutation_p.V67M|TSN_uc010yze.1_Missense_Mutation_p.V114M|TSN_uc010flt.2_Intron	NM_004622	NP_004613	Q15631	TSN_HUMAN	translin	114					DNA recombination	cytoplasm|nucleus	sequence-specific DNA binding			breast(2)|large_intestine(1)	3		Ovarian(717;0.0563)|Prostate(154;0.116)				AGAAACACTAGTGACTCGAGA	0.428000													58	101					0	0	1	0	0	
GALNT3	2591	broad.mit.edu	37	2	166606374	166606374	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:166606374G>A	uc010fph.1	-	10	2044	c.1657C>T	c.(1657-1659)CGG>TGG	p.R553W		NM_004482	NP_004473	Q14435	GALT3_HUMAN	polypeptide N-acetylgalactosaminyltransferase 3	553	Ricin B-type lectin.|Lumenal (Potential).				protein O-linked glycosylation via serine|protein O-linked glycosylation via threonine	Golgi cisterna membrane|integral to membrane|membrane fraction|nucleus|perinuclear region of cytoplasm	calcium ion binding|manganese ion binding|polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			central_nervous_system(2)|ovary(1)	3						ATGTTGTGCCGAATTTCATGT	0.403000													39	71					0	0	1	0	0	
SCN9A	6335	broad.mit.edu	37	2	167133552	167133552	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:167133552C>T	uc010fpl.2	-	16	3123	c.2782G>A	c.(2782-2784)GCT>ACT	p.A928T	uc002udp.2_Intron	NM_002977	NP_002968	Q15858	SCN9A_HUMAN	sodium channel, voltage-gated, type IX, alpha	939	II.					voltage-gated sodium channel complex	voltage-gated sodium channel activity			ovary(6)|central_nervous_system(5)|skin(2)	13					Lamotrigine(DB00555)|Lidocaine(DB00281)	GCTTGACCAGCGACCTCCATA	0.478000													17	241					0	0	1	0	0	
METTL8	79828	broad.mit.edu	37	2	172216943	172216943	+	Missense_Mutation	SNP	A	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:172216943A>G	uc010zdo.1	-	3	365	c.224T>C	c.(223-225)CTG>CCG	p.L75P	METTL8_uc002ugu.3_Missense_Mutation_p.L75P|METTL8_uc002ugv.3_Missense_Mutation_p.L75P|METTL8_uc002ugt.3_Missense_Mutation_p.L75P|METTL8_uc002ugs.3_Missense_Mutation_p.L25P|METTL8_uc010zdp.1_Missense_Mutation_p.L30P	NM_024770	NP_079046	B3KW44	B3KW44_HUMAN	methyltransferase like 8	75							methyltransferase activity			ovary(1)	1						TTGCTCTTCCAGAAGGACTCG	0.443000													8	15					0	0	1	0	0	
HOXD10	3236	broad.mit.edu	37	2	176981726	176981726	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:176981726G>A	uc002ukj.2	+	1	235	c.165G>A	c.(163-165)CCG>CCA	p.P55P		NM_002148	NP_002139	P28358	HXD10_HUMAN	homeobox D10	55						nucleus	sequence-specific DNA binding			ovary(1)	1			OV - Ovarian serous cystadenocarcinoma(117;0.0207)|Epithelial(96;0.18)	Colorectal(32;0.0226)|READ - Rectum adenocarcinoma(9;0.0556)		GACTGCTCCCGTCTCTGGCCA	0.488000													30	53					0	0	1	0	0	
PDE11A	50940	broad.mit.edu	37	2	178769850	178769850	+	Nonsense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:178769850G>T	uc002ulq.2	-	3	1454	c.1136C>A	c.(1135-1137)TCA>TAA	p.S379*	PDE11A_uc002ulr.2_Nonsense_Mutation_p.S129*|PDE11A_uc002uls.1_Nonsense_Mutation_p.S21*|PDE11A_uc002ult.1_Nonsense_Mutation_p.S129*|PDE11A_uc002ulu.1_Nonsense_Mutation_p.S21*	NM_016953	NP_058649	Q9HCR9	PDE11_HUMAN	phosphodiesterase 11A isoform 4	379					platelet activation|signal transduction	cytosol	3',5'-cyclic-AMP phosphodiesterase activity|3',5'-cyclic-GMP phosphodiesterase activity|metal ion binding			ovary(3)|large_intestine(1)	4			OV - Ovarian serous cystadenocarcinoma(117;0.00121)|Epithelial(96;0.00455)|all cancers(119;0.02)			TTCTTTCCTTGAGGCAGCAAA	0.358000									Primary_Pigmented_Nodular_Adrenocortical_Disease_Familial				13	23					3.27435e-08	3.43576e-08	1	1	0	
TTN	7273	broad.mit.edu	37	2	179548772	179548772	+	Missense_Mutation	SNP	T	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:179548772T>G	uc010zfg.1	-	130	29252	c.29028A>C	c.(29026-29028)AAA>AAC	p.K9676N	TTN_uc010zfh.1_Intron|TTN_uc010zfi.1_Intron|TTN_uc010zfj.1_Intron|TTN_uc002umz.1_Missense_Mutation_p.K6337N|TTN_uc010fre.1_Intron	NM_133378	NP_596869	Q8WZ42	TITIN_HUMAN	titin isoform N2-A	10603							ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			ovary(58)|stomach(19)|large_intestine(17)|lung(16)|skin(16)|breast(10)|pancreas(7)|kidney(4)|central_nervous_system(3)|urinary_tract(2)|upper_aerodigestive_tract(1)	153			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			GTTTCAGAACTTTTTCTTCTG	0.368000													10	41					0	0	1	0	0	
SLC23A3	151295	broad.mit.edu	37	2	220032917	220032917	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:220032917C>T	uc010zks.1	-	6	909	c.798G>A	c.(796-798)TCG>TCA	p.S266S	NHEJ1_uc002vjq.3_RNA|SLC23A3_uc010zkr.1_Silent_p.S274S|SLC23A3_uc010fwb.2_Missense_Mutation_p.R256Q|SLC23A3_uc002vjs.1_Missense_Mutation_p.G119S|SLC23A3_uc002vjt.1_Missense_Mutation_p.G126S	NM_001144889	NP_001138361	Q6PIS1	S23A3_HUMAN	solute carrier family 23 (nucleobase	266	Extracellular (Potential).				transmembrane transport	integral to membrane	protein binding|transporter activity				0		Renal(207;0.0474)		Epithelial(149;9.27e-07)|all cancers(144;0.000156)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		CCACACATACCGAAAGGAGCC	0.587000													12	27					0	0	1	0	0	
NCOA5	57727	broad.mit.edu	37	20	44698970	44698970	+	Missense_Mutation	SNP	G	A	A	rs41282786		TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr20:44698970G>A	uc002xrd.2	-	2	772	c.244C>T	c.(244-246)CGG>TGG	p.R82W	NCOA5_uc002xrc.2_5'UTR|NCOA5_uc002xre.2_Missense_Mutation_p.R82W	NM_020967	NP_066018	Q9HCD5	NCOA5_HUMAN	nuclear receptor coactivator 5	82	Arg/Asp-rich (mixed charge).|Transcription repression.				regulation of transcription, DNA-dependent|transcription, DNA-dependent|translation	nucleus	aminoacyl-tRNA ligase activity|ATP binding			central_nervous_system(1)|skin(1)	2		Myeloproliferative disorder(115;0.0122)				CTCACGTCCCGAACGTCGCGC	0.532000													62	117					0	0	1	0	0	
NFATC2	4773	broad.mit.edu	37	20	50140079	50140079	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr20:50140079C>T	uc002xwd.2	-	2	921	c.701G>A	c.(700-702)CGC>CAC	p.R234H	NFATC2_uc002xwc.2_Missense_Mutation_p.R234H|NFATC2_uc010zyv.1_Missense_Mutation_p.R15H|NFATC2_uc010zyw.1_Missense_Mutation_p.R15H|NFATC2_uc010zyx.1_Missense_Mutation_p.R214H|NFATC2_uc010zyy.1_Missense_Mutation_p.R15H|NFATC2_uc010zyz.1_Missense_Mutation_p.R15H|NFATC2_uc002xwe.2_Missense_Mutation_p.R214H	NM_173091	NP_775114	Q13469	NFAC2_HUMAN	nuclear factor of activated T-cells,	234	3 X approximate SP repeats.				B cell receptor signaling pathway|positive regulation of B cell proliferation|response to DNA damage stimulus|response to drug	actin cytoskeleton|nucleus|plasma membrane	protein binding|sequence-specific DNA binding transcription factor activity			ovary(2)	2	Hepatocellular(150;0.248)					GGGCGAGTGGCGGCCCAGGCA	0.662000													34	159					0	0	1	0	0	
SALL4	57167	broad.mit.edu	37	20	50405596	50405596	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr20:50405596G>A	uc002xwh.3	-	3	2647	c.2546C>T	c.(2545-2547)TCG>TTG	p.S849L	SALL4_uc010gii.2_Missense_Mutation_p.S412L|SALL4_uc002xwi.3_Missense_Mutation_p.S72L	NM_020436	NP_065169	Q9UJQ4	SALL4_HUMAN	sal-like 4	849					transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(2)	2						GGACAATGTCGAGGGTCCCAC	0.582000													13	45					0	0	1	0	0	
DIDO1	11083	broad.mit.edu	37	20	61513397	61513397	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr20:61513397G>A	uc002ydr.1	-	16	4175	c.3911C>T	c.(3910-3912)GCT>GTT	p.A1304V	DIDO1_uc002yds.1_Missense_Mutation_p.A1304V	NM_033081	NP_149072	Q9BTC0	DIDO1_HUMAN	death inducer-obliterator 1 isoform c	1304					apoptosis|transcription, DNA-dependent	cytoplasm|nucleus	zinc ion binding			ovary(3)|skin(3)	6	Breast(26;5.68e-08)					AGCAGACGAAGCGGTGGAGGA	0.602000													61	134					0	0	1	0	0	
ZBTB46	140685	broad.mit.edu	37	20	62422081	62422081	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr20:62422081G>A	uc002ygv.1	-	2	231	c.30C>T	c.(28-30)ATC>ATT	p.I10I	ZBTB46_uc002ygu.2_RNA	NM_025224	NP_079500	Q86UZ6	ZBT46_HUMAN	zinc finger and BTB domain containing 46	10					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	nucleic acid binding|zinc ion binding			large_intestine(1)|ovary(1)	2	all_cancers(38;2.09e-12)|all_epithelial(29;3.8e-14)|Lung NSC(23;7.61e-10)|all_lung(23;2.64e-09)					AGTGGGACGTGATTTCCATAT	0.567000													8	33					0	0	1	0	0	
ZNF512B	57473	broad.mit.edu	37	20	62597698	62597698	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr20:62597698G>A	uc002yhl.1	-	5	884	c.830C>T	c.(829-831)ACG>ATG	p.T277M		NM_020713	NP_065764	Q96KM6	Z512B_HUMAN	zinc finger protein 512B	277					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0	all_cancers(38;2.14e-11)|all_epithelial(29;3.41e-13)|Lung NSC(23;3.41e-09)|all_lung(23;1.06e-08)					CTTTGTTACCGTAATGGGTTT	0.577000													107	529					0	0	1	0	0	
C21orf99	149992	broad.mit.edu	37	21	14439197	14439197	+	RNA	SNP	G	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr21:14439197G>C	uc002yja.3	+	10		c.2715G>C				NR_026916				Homo sapiens C21orf99 protein (C21orf99) mRNA, complete cds.												0						AAGAAGAAGAGAAGAGAAGAA	0.289000													3	27					0	0	1	0	0	
GGTLC2	91227	broad.mit.edu	37	22	22988895	22988895	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr22:22988895C>T	uc010gtt.2	+	1	114	c.80C>T	c.(79-81)CCC>CTC	p.P27L	LOC96610_uc011aim.1_Intron|POM121L1P_uc011ait.1_5'Flank|GGTLC2_uc010gts.2_Missense_Mutation_p.P27L	NM_199127	NP_954578	Q14390	GGTL2_HUMAN	gamma-glutamyltransferase-like 4 isoform 1	27					glutathione biosynthetic process		gamma-glutamyltransferase activity			ovary(1)	1	all_hematologic(9;0.0135)|Acute lymphoblastic leukemia(84;0.17)	all_hematologic(6;1.3e-31)|Acute lymphoblastic leukemia(6;5.54e-23)		READ - Rectum adenocarcinoma(21;0.145)		TACTACAAGCCCGAGTTCTAC	0.602000													25	21					0	0	1	0	0	
SLC6A1	6529	broad.mit.edu	37	3	11060366	11060366	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr3:11060366G>A	uc010hdq.2	+	5	864	c.453G>A	c.(451-453)CTG>CTA	p.L151L		NM_003042	NP_003033	P30531	SC6A1_HUMAN	solute carrier family 6 (neurotransmitter	151	Extracellular (Potential).				neurotransmitter secretion	integral to plasma membrane	gamma-aminobutyric acid:sodium symporter activity|neurotransmitter:sodium symporter activity			ovary(1)|skin(1)	2		Ovarian(110;0.0392)		OV - Ovarian serous cystadenocarcinoma(96;0.00099)	Cocaine(DB00907)|Tiagabine(DB00906)	TTTACTACCTGTACAACTCCT	0.582000													13	34					0	0	1	0	0	
SEMA3B	7869	broad.mit.edu	37	3	50314117	50314117	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr3:50314117C>T	uc003cyu.2	+	19	2472	c.2230C>T	c.(2230-2232)CGC>TGC	p.R744C	SEMA3B_uc003cyt.2_Missense_Mutation_p.R743C|SEMA3B_uc003cyv.2_Missense_Mutation_p.R631C|SEMA3B_uc003cyw.2_Missense_Mutation_p.R467C|SEMA3B_uc010hli.2_Missense_Mutation_p.R636C|SEMA3B_uc003cyx.2_Missense_Mutation_p.R630C|SEMA3B_uc003cyy.2_Missense_Mutation_p.R401C|SEMA3B_uc011bdo.1_Missense_Mutation_p.R401C|C3orf45_uc003cyz.2_5'Flank	NM_004636	NP_004627	Q13214	SEM3B_HUMAN	semaphorin 3B isoform 1 precursor	744	Arg-rich (basic).				axon guidance|cell-cell signaling	endoplasmic reticulum|extracellular region|membrane	receptor activity			lung(2)|central_nervous_system(2)|kidney(1)|skin(1)	6				BRCA - Breast invasive adenocarcinoma(193;0.000272)|KIRC - Kidney renal clear cell carcinoma(197;0.00544)|Kidney(197;0.00605)		GCGGGGGCCGCGCAGCGCAAC	0.692000													7	8					0	0	1	0	0	
GLYCTK	132158	broad.mit.edu	37	3	52325055	52325055	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr3:52325055C>T	uc003ddo.2	+	3	553	c.457C>T	c.(457-459)CGG>TGG	p.R153W	GLYCTK_uc003ddq.2_Missense_Mutation_p.R153W|GLYCTK_uc003ddm.2_RNA|GLYCTK_uc003ddn.2_RNA|GLYCTK_uc003ddp.1_Missense_Mutation_p.R153W|GLYCTK_uc003ddr.2_5'Flank	NM_145262	NP_660305	Q8IVS8	GLCTK_HUMAN	glycerate kinase isoform 1	153					protein phosphorylation	Golgi apparatus|mitochondrion	ATP binding|glycerate kinase activity|protein binding				0				BRCA - Breast invasive adenocarcinoma(193;3.56e-05)|Kidney(197;0.00171)|KIRC - Kidney renal clear cell carcinoma(197;0.00194)|OV - Ovarian serous cystadenocarcinoma(275;0.235)		CGATGCGCTGCGGGCTGCACT	0.612000													45	20					0	0	1	0	0	
ERC2	26059	broad.mit.edu	37	3	56115004	56115004	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr3:56115004C>T	uc003dhr.1	-	7	1738	c.1482G>A	c.(1480-1482)GCG>GCA	p.A494A	ERC2_uc003dht.1_5'UTR	NM_015576	NP_056391	O15083	ERC2_HUMAN	cytomatrix protein p110	494	Potential.					cell junction|cytoplasm|cytoskeleton|growth cone|presynaptic membrane|synaptosome	protein binding			ovary(2)	2				KIRC - Kidney renal clear cell carcinoma(284;0.0667)|Kidney(284;0.0873)|OV - Ovarian serous cystadenocarcinoma(275;0.219)		GTAATCTCAGCGCATCTACCT	0.438000													5	11					0	0	1	0	0	
C3orf21	152002	broad.mit.edu	37	3	194790650	194790650	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr3:194790650C>T	uc003fum.3	-	4	1084	c.976G>A	c.(976-978)GGC>AGC	p.G326S	C3orf21_uc003ful.2_Missense_Mutation_p.G123S|C3orf21_uc003fuk.2_Missense_Mutation_p.G120S	NM_152531	NP_689744	Q8NBI6	CC021_HUMAN	hypothetical protein LOC152002	326						integral to membrane	transferase activity, transferring glycosyl groups				0	all_cancers(143;9.33e-09)|Ovarian(172;0.0634)		Epithelial(36;1.73e-20)|all cancers(36;1.42e-18)|OV - Ovarian serous cystadenocarcinoma(49;1.56e-17)|Lung(62;0.000117)|LUSC - Lung squamous cell carcinoma(58;0.000146)	GBM - Glioblastoma multiforme(46;1.36e-05)		CCGAGGTGGCCGCGGAAGTGG	0.642000													18	40					0	0	1	0	0	
RGS12	6002	broad.mit.edu	37	4	3418745	3418745	+	Nonsense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr4:3418745C>T	uc003ggw.2	+	8	3437	c.2533C>T	c.(2533-2535)CAG>TAG	p.Q845*	RGS12_uc010ics.1_Nonsense_Mutation_p.Q44*|RGS12_uc003ggv.2_Nonsense_Mutation_p.Q845*|RGS12_uc003ggy.1_Nonsense_Mutation_p.Q243*|RGS12_uc010ict.1_Nonsense_Mutation_p.Q197*|RGS12_uc003ggz.2_Nonsense_Mutation_p.Q197*|RGS12_uc010icu.1_Nonsense_Mutation_p.Q44*|RGS12_uc011bvs.1_Nonsense_Mutation_p.Q187*|RGS12_uc003gha.2_Nonsense_Mutation_p.Q187*|RGS12_uc010icv.2_Nonsense_Mutation_p.Q44*|RGS12_uc003ghb.2_Nonsense_Mutation_p.Q44*	NM_198229	NP_937872	O14924	RGS12_HUMAN	regulator of G-protein signalling 12 isoform 1	845						condensed nuclear chromosome|cytoplasm|plasma membrane	GTPase activator activity|receptor signaling protein activity			skin(1)	1				UCEC - Uterine corpus endometrioid carcinoma (64;0.168)		CCCGGACTCGCAGCAGGTCCC	0.602000													26	31					0	0	1	0	0	
BOD1L	259282	broad.mit.edu	37	4	13605585	13605585	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr4:13605585G>A	uc003gmz.1	-	10	3056	c.2939C>T	c.(2938-2940)TCA>TTA	p.S980L	BOD1L_uc010idr.1_Missense_Mutation_p.S317L	NM_148894	NP_683692	Q8NFC6	BOD1L_HUMAN	biorientation of chromosomes in cell division	980	Lys-rich.						DNA binding			ovary(5)|breast(1)	6						ACTATGTGCTGAAGAAGAAGC	0.388000													45	73					0	0	1	0	0	
MTTP	4547	broad.mit.edu	37	4	100503097	100503097	+	Missense_Mutation	SNP	C	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr4:100503097C>A	uc003hvc.3	+	3	353	c.97C>A	c.(97-99)CTG>ATG	p.L33M	MTTP_uc011cej.1_Missense_Mutation_p.L60M|MTTP_uc003hvb.2_Missense_Mutation_p.L33M	NM_000253	NP_000244	P55157	MTP_HUMAN	microsomal triglyceride transfer protein large	33	Vitellogenin.				lipid metabolic process|lipoprotein metabolic process	endoplasmic reticulum lumen	lipid binding|lipid transporter activity			ovary(3)|central_nervous_system(1)	4				OV - Ovarian serous cystadenocarcinoma(123;6.04e-09)	Hesperetin(DB01094)	TAATGACCGGCTGTACAAGCT	0.463000													37	53					5.34276e-22	5.85346e-22	1	1	0	
SGMS2	166929	broad.mit.edu	37	4	108816777	108816777	+	Missense_Mutation	SNP	C	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr4:108816777C>G	uc003hyl.3	+	3	623	c.68C>G	c.(67-69)ACT>AGT	p.T23S	uc003hym.1_Intron|SGMS2_uc003hyn.2_Missense_Mutation_p.T23S|SGMS2_uc003hyo.2_Missense_Mutation_p.T23S	NM_001136258	NP_001129730	Q8NHU3	SMS2_HUMAN	sphingomyelin synthase 2	23					sphingomyelin biosynthetic process	integral to Golgi membrane|integral to plasma membrane	ceramide cholinephosphotransferase activity|kinase activity|sphingomyelin synthase activity			lung(1)	1				OV - Ovarian serous cystadenocarcinoma(123;2.95e-05)	Choline(DB00122)	CCTACGAACACTTATGCAAGA	0.423000													17	40					0	0	1	0	0	
PCDH10	57575	broad.mit.edu	37	4	134071388	134071388	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr4:134071388C>T	uc003iha.2	+	1	919	c.93C>T	c.(91-93)GGC>GGT	p.G31G	uc003igy.2_5'Flank|PCDH10_uc003igz.2_Silent_p.G31G	NM_032961	NP_116586	Q9P2E7	PCD10_HUMAN	protocadherin 10 isoform 1 precursor	31	Cadherin 1.|Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(2)	2				LUSC - Lung squamous cell carcinoma(193;0.227)		AGGAACATGGCACTTTCGTGG	0.493000													23	152					0	0	1	0	0	
PCDH10	57575	broad.mit.edu	37	4	134071615	134071615	+	Missense_Mutation	SNP	A	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr4:134071615A>G	uc003iha.2	+	1	1146	c.320A>G	c.(319-321)CAG>CGG	p.Q107R	uc003igy.2_5'Flank|PCDH10_uc003igz.2_Missense_Mutation_p.Q107R	NM_032961	NP_116586	Q9P2E7	PCD10_HUMAN	protocadherin 10 isoform 1 precursor	107	Cadherin 1.|Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(2)	2				LUSC - Lung squamous cell carcinoma(193;0.227)		GAGCTGTTCCAGGTGGAGATC	0.572000													69	46					0	0	1	0	0	
SPATA4	132851	broad.mit.edu	37	4	177113976	177113976	+	Missense_Mutation	SNP	A	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr4:177113976A>T	uc003iuo.1	-	4	599	c.490T>A	c.(490-492)TTT>ATT	p.F164I		NM_144644	NP_653245	Q8NEY3	SPAT4_HUMAN	spermatogenesis associated 4	164					apoptosis|spermatogenesis						0		Breast(14;0.0011)|Prostate(90;0.0129)|Melanoma(52;0.0133)|Renal(120;0.0376)|all_hematologic(60;0.124)		all cancers(43;2.9e-20)|Epithelial(43;1.99e-17)|OV - Ovarian serous cystadenocarcinoma(60;2.58e-09)|GBM - Glioblastoma multiforme(59;0.000162)|STAD - Stomach adenocarcinoma(60;0.000543)|LUSC - Lung squamous cell carcinoma(193;0.096)		AAATTCACAAAGTCATCCTGG	0.313000													9	18					0	0	1	0	0	
RXFP3	51289	broad.mit.edu	37	5	33936956	33936956	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr5:33936956G>A	uc003jic.1	+	1	468	c.111G>A	c.(109-111)ACG>ACA	p.T37T		NM_016568	NP_057652	Q9NSD7	RL3R1_HUMAN	relaxin/insulin-like family peptide receptor 3	37	Extracellular (Potential).					integral to plasma membrane	N-formyl peptide receptor activity			upper_aerodigestive_tract(1)	1						CGGCCAACACGAGTGGTAACG	0.667000													68	39					0	0	1	0	0	
ARSI	340075	broad.mit.edu	37	5	149677329	149677329	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr5:149677329C>T	uc003lrv.2	-	2	1747	c.1158G>A	c.(1156-1158)ACG>ACA	p.T386T		NM_001012301	NP_001012301	Q5FYB1	ARSI_HUMAN	arylsulfatase family, member I precursor	386						endoplasmic reticulum|extracellular region	arylsulfatase activity|metal ion binding			ovary(1)|pancreas(1)	2			KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			GCAGGATCTCCGTGCGTGGTG	0.652000													16	14					0	0	1	0	0	
GFOD1	54438	broad.mit.edu	37	6	13365421	13365421	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr6:13365421C>T	uc003nat.1	-	2	1392	c.727G>A	c.(727-729)GGC>AGC	p.G243S	GFOD1_uc003nas.1_Missense_Mutation_p.G140S	NM_018988	NP_061861	Q9NXC2	GFOD1_HUMAN	glucose-fructose oxidoreductase domain	243						extracellular region	binding|oxidoreductase activity			ovary(2)	2	Breast(50;0.0296)|Ovarian(93;0.0454)	all_hematologic(90;0.135)	Epithelial(50;0.0348)|BRCA - Breast invasive adenocarcinoma(129;0.1)|all cancers(50;0.108)			TTGAACTCGCCGGGCACGTTG	0.657000													3	42					0	0	1	0	0	
C6orf153	88745	broad.mit.edu	37	6	42996916	42996916	+	Nonsense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr6:42996916C>T	uc003otp.1	+	7	738	c.730C>T	c.(730-732)CGA>TGA	p.R244*		NM_033112	NP_149103	Q96EU6	RRP36_HUMAN	hypothetical protein LOC88745	244	Nuclear localization signal (Potential).				ribosomal small subunit biogenesis|rRNA processing	nucleolus					0			Colorectal(64;0.00237)|all cancers(41;0.0034)|COAD - Colon adenocarcinoma(64;0.00473)|OV - Ovarian serous cystadenocarcinoma(102;0.0539)|KIRC - Kidney renal clear cell carcinoma(15;0.133)|Kidney(15;0.188)			TCGAAAGAGGCGACGAAATGC	0.502000													62	15					0	0	1	0	0	
DST	667	broad.mit.edu	37	6	56362226	56362226	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr6:56362226G>A	uc003pdf.2	-	76	13845	c.13817C>T	c.(13816-13818)CCG>CTG	p.P4606L	DST_uc003pcz.3_Missense_Mutation_p.P4428L|DST_uc011dxj.1_Missense_Mutation_p.P4457L|DST_uc011dxk.1_Missense_Mutation_p.P4468L|DST_uc003pcy.3_Missense_Mutation_p.P4102L	NM_001144769	NP_001138241	Q03001	DYST_HUMAN	dystonin isoform 2	6514	Spectrin 16.				cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere|Z disc	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein binding|protein C-terminus binding|protein homodimerization activity			ovary(7)|central_nervous_system(6)|upper_aerodigestive_tract(1)	14	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			ACCTCCCAGCGGTTTAGATGC	0.463000													48	25					0	0	1	0	0	
DDX43	55510	broad.mit.edu	37	6	74115481	74115481	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr6:74115481G>T	uc003pgw.2	+	6	1074	c.730G>T	c.(730-732)GAT>TAT	p.D244Y	DDX43_uc011dyn.1_RNA	NM_018665	NP_061135	Q9NXZ2	DDX43_HUMAN	DEAD (Asp-Glu-Ala-Asp) box polypeptide 43	244	Q motif.					intracellular	ATP binding|ATP-dependent RNA helicase activity|RNA binding			ovary(2)|upper_aerodigestive_tract(1)|skin(1)	4						CTGCACATTTGATGACGCCTT	0.358000													14	24					1.49906e-05	1.52986e-05	1	1	0	
TNRC18	84629	broad.mit.edu	37	7	5353457	5353457	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:5353457G>A	uc003soi.3	-	27	7414	c.7065C>T	c.(7063-7065)GAC>GAT	p.D2355D		NM_001080495	NP_001073964	O15417	TNC18_HUMAN	trinucleotide repeat containing 18	2355	Pro-rich.						DNA binding				0		Ovarian(82;0.142)		UCEC - Uterine corpus endometrioid carcinoma (126;0.195)|OV - Ovarian serous cystadenocarcinoma(56;5.32e-15)		TGGGGACCTCGTCTGTTGGGT	0.627000													10	25					0	0	1	0	0	
EPDR1	54749	broad.mit.edu	37	7	37988642	37988642	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:37988642C>T	uc003tfp.2	+	2	849	c.830C>T	c.(829-831)GCT>GTT	p.A277V	EPDR1_uc003tfq.2_Intron|EPDR1_uc010kxh.2_Missense_Mutation_p.A96V	NM_017549	NP_060019	Q9UM22	EPDR1_HUMAN	ependymin related protein 1 precursor	157					cell-matrix adhesion	extracellular region	calcium ion binding			upper_aerodigestive_tract(1)	1						AGAAAGTCAGCTAGATCCTGT	0.463000													14	34					0	0	1	0	0	
ZNF479	90827	broad.mit.edu	37	7	57187725	57187725	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:57187725G>T	uc010kzo.2	-	5	1668	c.1397C>A	c.(1396-1398)ACA>AAA	p.T466K		NM_033273	NP_150376	Q96JC4	ZN479_HUMAN	zinc finger protein 479	466	C2H2-type 11.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(3)|skin(1)	4			GBM - Glioblastoma multiforme(1;9.18e-12)			TTCTTCACATGTGTAGGGTCT	0.428000													6	121					0.000157383	0.000159525	1	1	0	
ZNF655	79027	broad.mit.edu	37	7	99170715	99170715	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:99170715G>T	uc003urh.2	+	3	1377	c.984G>T	c.(982-984)ATG>ATT	p.M328I	ZNF655_uc010lga.2_Missense_Mutation_p.M363I|ZNF655_uc010lgc.2_Missense_Mutation_p.M363I|ZNF655_uc003urj.2_Missense_Mutation_p.M328I|ZNF655_uc003urk.2_Missense_Mutation_p.M165I|ZNF655_uc010lgd.2_Missense_Mutation_p.M165I	NM_138494	NP_612503	Q8N720	ZN655_HUMAN	zinc finger protein 655 isoform a	328					G1 phase|regulation of mitotic cell cycle|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleolus	DNA binding|protein binding|zinc ion binding			ovary(1)	1	all_epithelial(64;3.19e-09)|Lung NSC(181;0.0066)|all_lung(186;0.011)|Esophageal squamous(72;0.0166)					ACAAAGAGATGCCCTGTAAGT	0.413000													32	60					1.58521e-26	1.7496e-26	1	1	0	
CHRM2	1129	broad.mit.edu	37	7	136699730	136699730	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:136699730G>A	uc003vtf.1	+	4	741	c.118G>A	c.(118-120)GGG>AGG	p.G40R	CHRM2_uc003vtg.1_Missense_Mutation_p.G40R|CHRM2_uc003vtj.1_Missense_Mutation_p.G40R|CHRM2_uc003vtk.1_Missense_Mutation_p.G40R|CHRM2_uc003vtl.1_Missense_Mutation_p.G40R|CHRM2_uc003vtm.1_Missense_Mutation_p.G40R|CHRM2_uc003vti.1_Missense_Mutation_p.G40R|CHRM2_uc003vto.1_Missense_Mutation_p.G40R|CHRM2_uc003vtn.1_Missense_Mutation_p.G40R|uc003vtp.1_Intron	NM_001006630	NP_001006631	P08172	ACM2_HUMAN	cholinergic receptor, muscarinic 2	40	Helical; Name=1; (By similarity).				activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway|G-protein signaling, coupled to cAMP nucleotide second messenger|nervous system development|regulation of heart contraction|response to virus	cell junction|integral to plasma membrane|postsynaptic membrane	muscarinic acetylcholine receptor activity|protein binding			ovary(4)|central_nervous_system(1)	5					Anisotropine Methylbromide(DB00517)|Atropine(DB00572)|Benzquinamide(DB00767)|Carbachol(DB00411)|Cryptenamine(DB00785)|Cyclizine(DB01176)|Desipramine(DB01151)|Diphenidol(DB01231)|Doxacurium(DB01334)|Doxacurium chloride(DB01135)|Flavoxate(DB01148)|Gallamine Triethiodide(DB00483)|Homatropine Methylbromide(DB00725)|Hyoscyamine(DB00424)|Ipratropium(DB00332)|Methotrimeprazine(DB01403)|Metixene(DB00340)|Metocurine(DB01336)|Mivacurium(DB01226)|Olanzapine(DB00334)|Oxybutynin(DB01062)|Oxyphencyclimine(DB00383)|Pilocarpine(DB01085)|Procyclidine(DB00387)|Promazine(DB00420)|Promethazine(DB01069)|Propiomazine(DB00777)|Rocuronium(DB00728)|Thiethylperazine(DB00372)|Tolterodine(DB01036)|Tridihexethyl(DB00505)|Triflupromazine(DB00508)	GACCATTATCGGGAACATCCT	0.448000													15	56					0	0	1	0	0	
OR2A2	442361	broad.mit.edu	37	7	143807591	143807591	+	Missense_Mutation	SNP	A	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:143807591A>T	uc011ktz.1	+	1	916	c.916A>T	c.(916-918)AGG>TGG	p.R306W		NM_001005480	NP_001005480	Q6IF42	OR2A2_HUMAN	olfactory receptor, family 2, subfamily A,	306	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			skin(2)	2	Melanoma(164;0.0783)					AGCACTCCAGAGGAAGAGGTC	0.443000													65	29					0	0	1	0	0	
DPP6	1804	broad.mit.edu	37	7	154593099	154593099	+	Missense_Mutation	SNP	A	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:154593099A>C	uc003wlk.2	+	13	1463	c.1334A>C	c.(1333-1335)AAG>ACG	p.K445T	DPP6_uc003wli.2_Missense_Mutation_p.K381T|DPP6_uc003wlm.2_Missense_Mutation_p.K383T|DPP6_uc011kvq.1_Missense_Mutation_p.K338T	NM_130797	NP_570629	P42658	DPP6_HUMAN	dipeptidyl-peptidase 6 isoform 1	445	Extracellular (Potential).				cell death|proteolysis	integral to membrane	dipeptidyl-peptidase activity|serine-type peptidase activity			pancreas(3)|breast(1)	4	all_neural(206;0.181)	all_hematologic(28;0.0044)|all_lung(21;0.0176)|Lung NSC(21;0.0204)	OV - Ovarian serous cystadenocarcinoma(82;0.0562)			GATGGCCGAAAGTTTTTCTTC	0.483000													4	6					0	0	1	0	0	
DPP6	1804	broad.mit.edu	37	7	154595588	154595588	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr7:154595588C>T	uc003wlk.2	+	14	1551	c.1422C>T	c.(1420-1422)AAC>AAT	p.N474N	DPP6_uc003wli.2_Silent_p.N410N|DPP6_uc003wlm.2_Silent_p.N412N|DPP6_uc011kvq.1_Silent_p.N367N	NM_130797	NP_570629	P42658	DPP6_HUMAN	dipeptidyl-peptidase 6 isoform 1	474	Extracellular (Potential).				cell death|proteolysis	integral to membrane	dipeptidyl-peptidase activity|serine-type peptidase activity			pancreas(3)|breast(1)	4	all_neural(206;0.181)	all_hematologic(28;0.0044)|all_lung(21;0.0176)|Lung NSC(21;0.0204)	OV - Ovarian serous cystadenocarcinoma(82;0.0562)			ACAGCAGCAACGACAACATCC	0.567000													9	21					0	0	1	0	0	
ZNF596	169270	broad.mit.edu	37	8	195985	195985	+	Nonsense_Mutation	SNP	C	T	T	rs140067348	byFrequency	TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr8:195985C>T	uc003wot.2	+	6	1426	c.1138C>T	c.(1138-1140)CGA>TGA	p.R380*	ZNF596_uc003wou.2_Nonsense_Mutation_p.R279*|ZNF596_uc003wov.2_Nonsense_Mutation_p.R380*|ZNF596_uc003wow.2_Nonsense_Mutation_p.R380*	NM_173539	NP_775810	Q8TC21	ZN596_HUMAN	zinc finger protein 596	380	C2H2-type 7.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		all_cancers(2;4.81e-29)|all_epithelial(2;5.03e-19)|Lung NSC(2;8.68e-08)|all_lung(2;1.52e-07)|Ovarian(12;0.00965)|Colorectal(14;0.0367)|all_neural(12;0.0837)|Myeloproliferative disorder(644;0.116)|all_hematologic(2;0.138)|Acute lymphoblastic leukemia(644;0.242)		Epithelial(5;3.77e-18)|all cancers(2;5.2e-17)|OV - Ovarian serous cystadenocarcinoma(5;5.37e-09)|BRCA - Breast invasive adenocarcinoma(11;1.7e-06)|Colorectal(2;6.51e-05)|READ - Rectum adenocarcinoma(2;0.0276)|COAD - Colon adenocarcinoma(149;0.0702)		TGTGCTTAAACGACATGAGAG	0.433000													25	20					0	0	1	0	0	
KCNU1	157855	broad.mit.edu	37	8	36788588	36788588	+	Silent	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr8:36788588G>A	uc010lvw.2	+	25	2943	c.2856G>A	c.(2854-2856)ACG>ACA	p.T952T	KCNU1_uc003xjw.2_RNA	NM_001031836	NP_001027006	A8MYU2	KCNU1_HUMAN	potassium channel, subfamily U, member 1	952	Cytoplasmic (Potential).					voltage-gated potassium channel complex	binding|large conductance calcium-activated potassium channel activity|voltage-gated potassium channel activity			ovary(1)	1				KIRC - Kidney renal clear cell carcinoma(67;0.0504)|Kidney(114;0.0634)		ATAGCTGCACGTCGCTCTTGT	0.448000													31	18					0	0	1	0	0	
PXDNL	137902	broad.mit.edu	37	8	52321899	52321899	+	Missense_Mutation	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr8:52321899C>T	uc003xqu.3	-	17	2386	c.2285G>A	c.(2284-2286)CGC>CAC	p.R762H	PXDNL_uc003xqt.3_RNA	NM_144651	NP_653252	A1KZ92	PXDNL_HUMAN	peroxidasin homolog-like precursor	762					hydrogen peroxide catabolic process	extracellular space	heme binding|peroxidase activity			ovary(1)|pancreas(1)	2		all_cancers(86;0.107)|Lung NSC(129;0.00641)|all_epithelial(80;0.00716)|all_lung(136;0.015)				GCGGGGCGCGCGGATGCCGTC	0.791000													9	4					0	0	1	0	0	
ADCY8	114	broad.mit.edu	37	8	131955619	131955619	+	Missense_Mutation	SNP	G	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr8:131955619G>T	uc003ytd.3	-	4	1587	c.1331C>A	c.(1330-1332)GCC>GAC	p.A444D	ADCY8_uc010mds.2_Missense_Mutation_p.A444D	NM_001115	NP_001106	P40145	ADCY8_HUMAN	adenylate cyclase 8	444	Cytoplasmic (Potential).				activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity|activation of protein kinase A activity|cellular response to glucagon stimulus|energy reserve metabolic process|inhibition of adenylate cyclase activity by G-protein signaling pathway|nerve growth factor receptor signaling pathway|synaptic transmission|transmembrane transport|water transport	integral to membrane|membrane fraction|plasma membrane	ATP binding|calcium- and calmodulin-responsive adenylate cyclase activity|metal ion binding			skin(4)|large_intestine(1)|central_nervous_system(1)	6	Esophageal squamous(12;0.00693)|Ovarian(258;0.00707)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.000538)			ATCAAATCTGGCAAAGAGCTC	0.448000										HNSCC(32;0.087)			17	45					1.28384e-07	1.32842e-07	1	1	0	
ZFAT	57623	broad.mit.edu	37	8	135614315	135614315	+	Silent	SNP	C	T	T			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr8:135614315C>T	uc003yup.2	-	6	1822	c.1647G>A	c.(1645-1647)CCG>CCA	p.P549P	ZFAT_uc003yun.2_Silent_p.P537P|ZFAT_uc003yuo.2_Silent_p.P537P|ZFAT_uc010meh.2_Silent_p.P537P|ZFAT_uc010mei.2_RNA|ZFAT_uc003yuq.2_Silent_p.P537P|ZFAT_uc010mej.2_Silent_p.P487P|ZFAT_uc003yur.2_Silent_p.P537P	NM_020863	NP_065914	Q9P243	ZFAT_HUMAN	zinc finger protein 406 isoform ZFAT-1	549					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|nucleus	DNA binding|zinc ion binding			central_nervous_system(1)	1	all_epithelial(106;8.26e-19)|Lung NSC(106;3.47e-07)|all_lung(105;1.39e-06)|Ovarian(258;0.0102)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.0432)			CAGGGGCCTCCGGCTCCTTCC	0.652000													3	6					0	0	1	0	0	
RCL1	10171	broad.mit.edu	37	9	4849472	4849472	+	Missense_Mutation	SNP	A	G	G			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr9:4849472A>G	uc003zis.2	+	8	1151	c.893A>G	c.(892-894)CAA>CGA	p.Q298R	RCL1_uc003zit.2_Missense_Mutation_p.Q140R|RCL1_uc010mhk.1_Missense_Mutation_p.Q140R|RCL1_uc010mhl.1_Missense_Mutation_p.Q112R	NM_005772	NP_005763	Q9Y2P8	RCL1_HUMAN	RNA terminal phosphate cyclase-like 1	298					ribosome biogenesis|RNA processing	nucleolus	RNA-3'-phosphate cyclase activity				0	all_hematologic(13;0.137)	Acute lymphoblastic leukemia(23;0.0206)|Breast(48;0.147)		GBM - Glioblastoma multiforme(50;0.0244)		TCGACCAACCAAAGCCTGGCG	0.433000													4	36					0	0	1	0	0	
FAM129B	64855	broad.mit.edu	37	9	130271314	130271314	+	Nonsense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr9:130271314G>A	uc004brh.2	-	10	1460	c.1258C>T	c.(1258-1260)CGA>TGA	p.R420*	FAM129B_uc004bri.2_Nonsense_Mutation_p.R407*|FAM129B_uc004brj.3_Nonsense_Mutation_p.R420*	NM_022833	NP_073744	Q96TA1	NIBL1_HUMAN	hypothetical protein LOC64855 isoform 1	420							protein binding				0						ACATCAAATCGCTGCTGCAGC	0.617000													16	24					0	0	1	0	0	
NTNG2	84628	broad.mit.edu	37	9	135073611	135073611	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr9:135073611G>A	uc004cbh.2	+	3	1248	c.472G>A	c.(472-474)GGG>AGG	p.G158R		NM_032536	NP_115925	Q96CW9	NTNG2_HUMAN	netrin G2 precursor	158	Laminin N-terminal.				axonogenesis	anchored to plasma membrane					0				OV - Ovarian serous cystadenocarcinoma(145;1.23e-05)|Epithelial(140;0.000173)		CCTGGACAACGGGCGCACCTG	0.652000													23	28					0	0	1	0	0	
Unknown	0	broad.mit.edu	37	MT	12779	12779	+	RNA	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrM:12779G>A	uc004cox.3	+	1		c.443G>A			uc004coy.2_5'Flank					Homo sapiens NADH dehydrogenase subunit 5 (MTND5) mRNA, RNA 5, complete cds; mitochondrial gene for mitochondrial product.																		AGAGGGCGTAGGAATTATATC	0.428000													17	4					0	0	1	0	0	
Unknown	0	broad.mit.edu	37	MT	13069	13069	+	RNA	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrM:13069G>A	uc004cox.3	+	1		c.733G>A			uc004coy.2_5'Flank|uc004coz.1_5'Flank					Homo sapiens NADH dehydrogenase subunit 5 (MTND5) mRNA, RNA 5, complete cds; mitochondrial gene for mitochondrial product.																		CCCCAGTCTCAGCCCTACTCC	0.537000													41	4					0	0	1	0	0	
Unknown	0	broad.mit.edu	37	MT	13111	13111	+	RNA	SNP	T	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrM:13111T>C	uc004cox.3	+	1		c.775T>C			uc004coy.2_5'Flank|uc004coz.1_5'Flank					Homo sapiens NADH dehydrogenase subunit 5 (MTND5) mRNA, RNA 5, complete cds; mitochondrial gene for mitochondrial product.																		CAGGAATCTTCTTACTCATCC	0.527000													29	1					0	0	1	0	0	
ARHGAP6	395	broad.mit.edu	37	X	11174711	11174711	+	Missense_Mutation	SNP	G	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrX:11174711G>C	uc004cup.1	-	10	2718	c.1845C>G	c.(1843-1845)AGC>AGG	p.S615R	ARHGAP6_uc004cuo.1_RNA|ARHGAP6_uc004cur.1_Missense_Mutation_p.S615R|ARHGAP6_uc004cum.1_Missense_Mutation_p.S412R|ARHGAP6_uc004cun.1_Missense_Mutation_p.S435R|ARHGAP6_uc010neb.1_Missense_Mutation_p.S437R|ARHGAP6_uc011mif.1_Missense_Mutation_p.S412R	NM_013427	NP_038286	O43182	RHG06_HUMAN	Rho GTPase activating protein 6 isoform 1	615					actin filament polymerization|activation of phospholipase C activity|negative regulation of focal adhesion assembly|negative regulation of stress fiber assembly|Rho protein signal transduction	actin filament|cytosol	phospholipase activator activity|phospholipase binding|Rho GTPase activator activity|SH3 domain binding|SH3/SH2 adaptor activity			urinary_tract(1)|lung(1)	2						TCTCTAACAGGCTGATCAGCA	0.458000													6	5					0	0	1	0	0	
MAP3K15	389840	broad.mit.edu	37	X	19387274	19387274	+	Missense_Mutation	SNP	G	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrX:19387274G>A	uc004czk.1	-	26	3526	c.1889C>T	c.(1888-1890)GCG>GTG	p.A630V	MAP3K15_uc004czj.1_Missense_Mutation_p.A590V|MAP3K15_uc004czi.1_Missense_Mutation_p.A89V	NM_001001671	NP_001001671	Q6ZN16	M3K15_HUMAN	mitogen-activated protein kinase kinase kinase	1155							ATP binding|MAP kinase kinase kinase activity|metal ion binding			ovary(3)|lung(2)|stomach(1)|skin(1)	7	Hepatocellular(33;0.183)					GCCCTCTTCCGCTTCATCCAT	0.587000													37	22					0	0	1	0	0	
GPR174	84636	broad.mit.edu	37	X	78426762	78426762	+	Missense_Mutation	SNP	T	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrX:78426762T>A	uc004edg.1	+	1	294	c.258T>A	c.(256-258)TTT>TTA	p.F86L		NM_032553	NP_115942	Q9BXC1	GP174_HUMAN	putative purinergic receptor FKSG79	86	Extracellular (Potential).					integral to membrane|plasma membrane	purinergic nucleotide receptor activity, G-protein coupled			lung(1)|central_nervous_system(1)	2						ACTGGCCATTTGGGCCTGGTC	0.423000										HNSCC(63;0.18)			10	1					0	0	1	0	0	
AMOT	154796	broad.mit.edu	37	X	112048266	112048266	+	Missense_Mutation	SNP	C	T	T	rs139517376		TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrX:112048266C>T	uc004epr.2	-	5	1685	c.1685G>A	c.(1684-1686)CGT>CAT	p.R562H	AMOT_uc004eps.2_Missense_Mutation_p.R153H	NM_001113490	NP_001106962	Q4VCS5	AMOT_HUMAN	angiomotin isoform 1	562	Potential.				actin cytoskeleton organization|cell-cell junction assembly|negative regulation of angiogenesis|negative regulation of vascular permeability|positive regulation of blood vessel endothelial cell migration|positive regulation of cell size|positive regulation of stress fiber assembly|regulation of cell migration	actin filament|cell surface|cytoplasm|endocytic vesicle|external side of plasma membrane|integral to membrane|lamellipodium|ruffle|stress fiber|tight junction|tight junction	angiostatin binding|protein binding|receptor activity			ovary(1)	1						ATTGGTAGAACGGGCAGTGGC	0.517000													76	41					0	0	1	0	0	
Unknown	0	broad.mit.edu	37	X	155252868	155252868	+	Silent	SNP	T	A	A			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrX:155252868T>A	uc004fnw.1	+	6	1571	c.912T>A	c.(910-912)CCT>CCA	p.P304P	uc004fnx.3_Silent_p.P90P	NM_182905	NP_878908			WAS protein family homolog 1																		TAGCCGAGCCTCTCAAGGCAG	0.632000													6	7					0	0	1	0	0	
NOTCH3	4854	broad.mit.edu	37	19	15311632	15311632	+	Frame_Shift_Del	DEL	G	-	-			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr19:15311632delG	uc002nan.2	-	1	161	c.85delC	c.(85-87)CTGfs	p.L29fs	NOTCH3_uc002nao.1_Frame_Shift_Del_p.L29fs	NM_000435	NP_000426	Q9UM47	NOTC3_HUMAN	Notch homolog 3 precursor	29					Notch receptor processing|Notch signaling pathway|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to membrane|nucleoplasm|plasma membrane	calcium ion binding|protein binding|receptor activity			lung(8)|ovary(5)|skin(4)|prostate(2)|central_nervous_system(1)|breast(1)	21			OV - Ovarian serous cystadenocarcinoma(3;2.6e-20)|Epithelial(3;1.34e-16)|all cancers(3;5.13e-15)			AGCAGCAGCAGGGGCAGCGCC	0.597													2	4	---	---	---	---						.
FOSL2	2355	broad.mit.edu	37	2	28627222	28627223	+	Frame_Shift_Ins	INS	-	C	C			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr2:28627222_28627223insC	uc002rma.2	+	2	1160_1161	c.351_352insC	c.(349-354)GAGCAGfs	p.E117fs	FOSL2_uc010ymi.1_Frame_Shift_Ins_p.E78fs	NM_005253	NP_005244	P15408	FOSL2_HUMAN	FOS-like antigen 2	117_118					cell death|regulation of transcription from RNA polymerase II promoter	nucleus	protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			ovary(2)|breast(1)	3	Acute lymphoblastic leukemia(172;0.155)					GGAGAGATGAGCAGGTACAGCT	0.604													34	69	---	---	---	---						.
TMEM161B	153396	broad.mit.edu	37	5	87501702	87501703	+	Frame_Shift_Ins	INS	-	A	A	rs78741910		TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chr5:87501702_87501703insA	uc003kjc.2	-	8	853_854	c.728_729insT	c.(727-729)TTGfs	p.L243fs	TMEM161B_uc011cty.1_Frame_Shift_Ins_p.L232fs|TMEM161B_uc010jax.2_RNA|TMEM161B_uc011ctz.1_Frame_Shift_Ins_p.L110fs|TMEM161B_uc011ctx.1_Frame_Shift_Ins_p.L61fs	NM_153354	NP_699185	Q8NDZ6	T161B_HUMAN	transmembrane protein 161B	243	Helical; (Potential).					integral to membrane				skin(2)	2		all_cancers(142;0.000275)|Lung NSC(167;0.00901)|all_lung(232;0.0111)|Colorectal(57;0.0959)|Ovarian(174;0.1)		OV - Ovarian serous cystadenocarcinoma(54;6.24e-36)|Epithelial(54;6.8e-31)|all cancers(79;1.07e-26)		CAGGAAATGTCAAAAAAGCCCC	0.342													19	25	---	---	---	---						.
XIST	7503	broad.mit.edu	37	X	73072261	73072261	+	RNA	DEL	A	-	-			TCGA-IP-7968-01A-11D-2201-08	TCGA-IP-7968-11A-01D-2201-08									Somatic	Phase_I	Capture				Illumina GAIIx	3cd2ff4e-689b-4c9f-87b7-083a64c1e68f	28c72da0-4ad9-4df1-8584-302a03dfb8f0	g.chrX:73072261delA	uc004ebm.1	-	1		c.328delT				NR_001564				Homo sapiens cDNA: FLJ21545 fis, clone COL06195.												0						ACTGATCCACAAAAAACAGAG	0.333													2	4	---	---	---	---						.
