Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
UVSSA	57654	broad.mit.edu	37	4	1374010	1374010	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr4:1374010C>T	uc003gde.4	+	10	2191	c.1744C>T	c.(1744-1746)Cgg>Tgg	p.R582W	UVSSA_uc010ibv.3_Missense_Mutation_p.R133W	NM_020894	NP_065945	Q2YD98	K1530_HUMAN	Homo sapiens KIAA1530 (KIAA1530), mRNA.	582																	GCGCCAAGACCGGCTGAAGGT	0.716000													3	23					0	0	1	0	0
AJAP1	55966	broad.mit.edu	37	1	4832438	4832438	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr1:4832438G>A	uc001alm.1	+	3	1397	c.1016G>A	c.(1015-1017)cGg>cAg	p.R339Q	AJAP1_uc001aln.3_Missense_Mutation_p.R339Q	NM_001042478	NP_061324	Q9UKB5	AJAP1_HUMAN	Homo sapiens adherens junctions associated protein 1 (AJAP1), transcript variant 2, mRNA.	339	Targeting signals.				cell adhesion	adherens junction|apical plasma membrane|basolateral plasma membrane|integral to membrane				endometrium(4)|large_intestine(6)|lung(11)|ovary(1)|prostate(1)|urinary_tract(1)	24	all_cancers(77;0.071)|Ovarian(185;0.0721)	all_cancers(23;1.77e-36)|all_epithelial(116;1.26e-21)|all_lung(118;3.51e-08)|Lung NSC(185;3.47e-06)|all_neural(13;8.84e-06)|all_hematologic(16;7.61e-05)|Breast(487;0.000507)|Renal(390;0.0007)|Colorectal(325;0.00117)|Hepatocellular(190;0.0071)|Glioma(11;0.0155)|Myeloproliferative disorder(586;0.0258)|Ovarian(437;0.0409)|Lung SC(97;0.133)|Medulloblastoma(700;0.215)		Epithelial(90;3.89e-35)|OV - Ovarian serous cystadenocarcinoma(86;1.97e-19)|GBM - Glioblastoma multiforme(42;3.71e-19)|Colorectal(212;4.57e-06)|COAD - Colon adenocarcinoma(227;0.00019)|Kidney(185;0.000969)|BRCA - Breast invasive adenocarcinoma(365;0.00122)|STAD - Stomach adenocarcinoma(132;0.00578)|KIRC - Kidney renal clear cell carcinoma(229;0.0126)|READ - Rectum adenocarcinoma(331;0.0689)		CCCTCGGCCCGGGTGCCCAGC	0.617000													4	43					0	0	1	0	0
TBXA2R	6915	broad.mit.edu	37	19	3600480	3600480	+	Silent	SNP	G	G	A			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr19:3600480G>A	uc021umv.1	-	1	540	c.153C>T	c.(151-153)ggC>ggT	p.G51G	TBXA2R_uc002lyg.2_Silent_p.G51G	NM_201636	NP_963998	P21731	TA2R_HUMAN	Homo sapiens thromboxane A2 receptor (TBXA2R), transcript variant b, mRNA.	51					platelet activation	integral to plasma membrane	guanyl-nucleotide exchange factor activity|protein binding|thromboxane A2 receptor activity			kidney(1)|lung(2)|ovary(1)|prostate(3)|upper_aerodigestive_tract(1)	8		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.00253)|STAD - Stomach adenocarcinoma(1328;0.18)	Ridogrel(DB01207)	CCTGCCGCGCGCCCGCCAGCA	0.706000													7	19					0	0	1	0	0
abParts	0	broad.mit.edu	37	14	106552349	106552349	+	RNA	SNP	G	G	C			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr14:106552349G>C	uc021ser.1	-	1994		c.36818C>G								Parts of antibodies, mostly variable regions.																		CAGATACAGGGAGTTCTTGGC	0.502000													75	140					0	0	1	0	0
POU2F3	25833	broad.mit.edu	37	11	120169033	120169033	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr11:120169033C>T	uc010rzk.2	+	3	342	c.7C>T	c.(7-9)Cct>Tct	p.P3S	POU2F3_uc021qrk.1_Silent_p.H66H|POU2F3_uc001pxc.3_Silent_p.H64H|POU2F3_uc010rzl.2_5'UTR			Q9UKI9	PO2F3_HUMAN	Homo sapiens POU class 2 homeobox 3 (POU2F3), transcript variant 1, mRNA.	0					negative regulation by host of viral transcription	cytoplasm	sequence-specific DNA binding			large_intestine(5)|lung(7)|ovary(2)|prostate(2)|skin(1)	17		Breast(109;0.0011)|Medulloblastoma(222;0.0425)|Hepatocellular(160;0.0831)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;6.85e-06)		GGCCATGCCACCTGAGTCAAG	0.537000													61	151					0	0	1	0	0
GNAO1	2775	broad.mit.edu	37	16	56309933	56309933	+	Silent	SNP	C	C	T			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr16:56309933C>T	uc002eit.4	+	2	1149	c.252C>T	c.(250-252)atC>atT	p.I84I	GNAO1_uc002eiu.4_Silent_p.I84I	NM_138736	NP_620073	P09471	GNAO_HUMAN	Homo sapiens guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1), transcript variant 2, mRNA.	84					G-protein signaling, coupled to cAMP nucleotide second messenger|dopamine receptor signaling pathway|muscle contraction	heterotrimeric G-protein complex	G-protein beta/gamma-subunit complex binding|GTP binding|GTPase activity|metabotropic serotonin receptor binding|signal transducer activity			breast(2)|endometrium(3)|kidney(1)|large_intestine(6)|lung(4)|prostate(1)	17		all_neural(199;0.159)				TGGCAGCCATCGTCCGGGCCA	0.502000													12	44					0	0	1	0	0
DPP8	54878	broad.mit.edu	37	15	65743407	65743407	+	Missense_Mutation	SNP	T	T	G			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr15:65743407T>G	uc002aov.3	-	18	4082	c.2504A>C	c.(2503-2505)aAt>aCt	p.N835T	DPP8_uc002aow.3_Missense_Mutation_p.N835T|DPP8_uc010uiv.2_Non-coding_Transcript|DPP8_uc021soz.1_Missense_Mutation_p.N819T|DPP8_uc002aox.3_Missense_Mutation_p.N819T|DPP8_uc002aoy.3_Missense_Mutation_p.N784T|DPP8_uc002aoz.3_Missense_Mutation_p.N719T|DPP8_uc010bhj.3_Missense_Mutation_p.N835T|DPP8_uc010bhi.3_Missense_Mutation_p.N138T	NM_130434	NP_569118	Q6V1X1	DPP8_HUMAN	Homo sapiens dipeptidyl-peptidase 8 (DPP8), transcript variant 1, mRNA.	835					immune response|proteolysis	cytoplasm|membrane|nucleus	aminopeptidase activity|dipeptidyl-peptidase activity|serine-type peptidase activity			NS(1)|breast(2)|endometrium(3)|large_intestine(11)|lung(11)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	36						AAAATGGACATTCTCATCCAG	0.358000													37	78					0	0	1	0	0
WDR11	55717	broad.mit.edu	37	10	122612090	122612090	+	Missense_Mutation	SNP	T	T	G			TCGA-DJ-A4V5-01A-11D-A257-08	TCGA-DJ-A4V5-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	303e4531-b4c2-4f91-84ba-6246bd119c87	a9b59b90-c24f-48a9-b818-31a9eb1e2d87	g.chr10:122612090T>G	uc021pzt.1	+	1	387	c.141T>G	c.(139-141)gaT>gaG	p.D47E	LOC283089_uc001lfb.1_5'Flank|WDR11_uc010qte.2_Missense_Mutation_p.D47E|WDR11_uc001lfd.1_5'UTR	NM_018117	NP_060587	Q9BZH6	WDR11_HUMAN	Homo sapiens WD repeat domain 11 (WDR11), mRNA.	47						integral to membrane				breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(11)|lung(9)|prostate(2)|skin(2)|stomach(5)	38						TAGTGATTGATTCCATTACTG	0.368000													15	22					0	0	1	0	0
