Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
AAAS	0	genome.wustl.edu	37	12	53708115	53708115	+	Missense_Mutation	SNP	A	A	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	12	53708115	53708115	A	G	SNP	AAAS	ENST00000209873	human	ensembl	69_37n	-1	known	missense	c.656	p.I219T	1.000	smart_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	AAAS	HGNC	ENSG00000094914	86	0	0.00	52	17	24.64	-	-	-
AADAT	0	genome.wustl.edu	37	4	170988516	170988516	+	Silent	SNP	G	G	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	4	170988516	170988516	G	A	SNP	AADAT	ENST00000509167	human	ensembl	69_37n	-1	known	silent	c.936	p.H312	0.836	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase_major_dom	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase_major_dom	-	no_errors	AADAT	HGNC	ENSG00000109576	85	0	0.00	90	23	20.35	-	-	-
ABCB8	0	genome.wustl.edu	37	7	150742383	150742384	+	Frame_Shift_Ins	INS	-	-	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	7	150742383	150742384	-	C	INS	ABCB8	ENST00000297504	human	ensembl	69_37n	+1	known	frame_shift_ins	c.2155_2156	p.P721fs	0.000:0.001	NULL	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_ABC_transptrTM_dom_typ1,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC_transporter_type1	-	no_errors	ABCB8	HGNC	ENSG00000197150	29	0	0.00	22	4	15.38	-	-	-
ACTL6B	0	genome.wustl.edu	37	7	100245130	100245131	+	Frame_Shift_Ins	INS	-	-	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	7	100245130	100245131	-	G	INS	ACTL6B	ENST00000160382	human	ensembl	69_37n	-1	known	frame_shift_ins	c.696_695	p.N233fs	1.000:1.000	pfam_Actin-like,smart_Actin-like	pfam_Actin-like,smart_Actin-like,prints_Actin-like	-	no_errors	ACTL6B	HGNC	ENSG00000077080	13	0	0.00	9	4	30.77	-	-	-
ATP9B	0	genome.wustl.edu	37	18	77137328	77137328	+	Missense_Mutation	SNP	T	T	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	18	77137328	77137328	T	G	SNP	ATP9B	ENST00000426216	human	ensembl	69_37n	+1	known	missense	c.3389	p.L1130R	1.000	tigrfam_ATPase_P-typ_Plipid-transl	pfam_ATPase_P-typ_ATPase-assoc-dom,pfam_Dehalogen-like_hydro,superfamily_HAD-like_dom,superfamily_ATPase_cation_domN,prints_ATPase_P-typ_ion-transptr,tigrfam_ATPase_P-typ_Plipid-transl,tigrfam_ATPase_P-typ_ion-transptr	-	no_errors	ATP9B	HGNC	ENSG00000166377	43	0	0.00	25	10	28.57	-	-	-
BOP1	0	genome.wustl.edu	37	8	145512978	145512979	+	Frame_Shift_Ins	INS	-	-	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	8	145512978	145512979	-	G	INS	BOP1	ENST00000307404	human	ensembl	69_37n	-1	known	frame_shift_ins	c.107_106	p.L36fs	0.008:0.001	NULL	pfam_BOP1_N_dom,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	BOP1	HGNC	ENSG00000170727	19	0	0.00	17	2	10.53	-	-	-
C3orf43	0	genome.wustl.edu	37	3	196234930	196234930	+	Missense_Mutation	SNP	C	C	T			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	3	196234930	196234930	C	T	SNP	C3orf43	ENST00000397537	human	ensembl	69_37n	-1	known	missense	c.473	p.R158K	0.146	NULL	NULL	-	no_errors	C3orf43	HGNC	ENSG00000214097	183	0	0.00	111	22	16.54	-	-	-
CBX2	0	genome.wustl.edu	37	17	77758219	77758220	+	Frame_Shift_Ins	INS	-	-	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	17	77758219	77758220	-	C	INS	CBX2	ENST00000310942	human	ensembl	69_37n	+1	known	frame_shift_ins	c.977_978	p.H329fs	0.033:0.000	NULL	pfam_Chromo_domain,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,pfscan_Chromo_domain/shadow	-	no_errors	CBX2	HGNC	ENSG00000173894	12	0	0.00	4	2	33.33	-	-	-
CCDC48	0	genome.wustl.edu	37	3	128753127	128753128	+	Frame_Shift_Ins	INS	-	-	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	3	128753127	128753128	-	A	INS	CCDC48	ENST00000436022	human	ensembl	69_37n	+1	known	frame_shift_ins	c.93_94	p.T31fs	0.023:0.020	NULL	NULL	-	no_errors	CCDC48	HGNC	ENSG00000114654	30	0	0.00	14	10	41.67	-	-	-
CDH24	0	genome.wustl.edu	37	14	23523727	23523728	+	Frame_Shift_Ins	INS	-	-	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	14	23523727	23523728	-	G	INS	CDH24	ENST00000267383	human	ensembl	69_37n	-1	known	frame_shift_ins	c.772_771	p.K257fs	1.000:1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH24	HGNC	ENSG00000139880	29	0	0.00	17	5	22.73	-	-	-
CSAD	0	genome.wustl.edu	37	12	53552403	53552403	+	Missense_Mutation	SNP	G	G	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	12	53552403	53552403	G	A	SNP	CSAD	ENST00000379850	human	ensembl	69_37n	-1	novel	missense	c.1450	p.R484W	0.061	superfamily_PyrdxlP-dep_Trfase_major_dom	pfam_PyrdxlP-dep_de-COase,pfam_Aminotrans_V/Cys_dSase,pfam_ArAA_b-elim_lyase/Thr_aldolase,superfamily_PyrdxlP-dep_Trfase_major_dom	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	CSAD	HGNC	ENSG00000139631	35	0	0.00	18	10	35.71	-	-	-
CTNNA2	0	genome.wustl.edu	37	2	80773103	80773103	+	Frame_Shift_Del	DEL	C	C	-			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	2	80773103	80773103	C	-	DEL	CTNNA2	ENST00000361291	human	ensembl	69_37n	+1	known	frame_shift_del	c.1557	p.F519fs	1.000	pfam_Vinculin/catenin,superfamily_Vinculin/catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTNNA2	HGNC	ENSG00000066032	62	0	0.00	39	52	55.32	-	-	-
EDDM3A	0	genome.wustl.edu	37	14	21216114	21216114	+	Missense_Mutation	SNP	C	C	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	14	21216114	21216114	C	A	SNP	EDDM3A	ENST00000326842	human	ensembl	69_37n	+1	known	missense	c.375	p.F125L	0.315	superfamily_RNaseA_domain	superfamily_RNaseA_domain	-	no_errors	EDDM3A	HGNC	ENSG00000181562	160	0	0.00	108	16	12.90	-	-	-
ENPP7	0	genome.wustl.edu	37	17	77709202	77709203	+	Frame_Shift_Ins	INS	-	-	CC			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	17	77709202	77709203	-	CC	INS	ENPP7	ENST00000328313	human	ensembl	69_37n	+1	known	frame_shift_ins	c.760_761	p.K254fs	0.544:0.531	pfam_Phosphodiest/P_Trfase,superfamily_Alkaline_phosphatase_core	pfam_Phosphodiest/P_Trfase,pfam_Metalloenzyme,superfamily_Alkaline_phosphatase_core	-	no_errors	ENPP7	HGNC	ENSG00000182156	38	0	0.00	37	19	33.93	-	-	-
GDAP1	0	genome.wustl.edu	37	8	75276444	75276444	+	Missense_Mutation	SNP	A	A	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	8	75276444	75276444	A	G	SNP	GDAP1	ENST00000220822	human	ensembl	69_37n	+1	known	missense	c.919	p.T307A	1.000	NULL	pfam_Glutathione_S-Trfase_N,pfam_GST_C,superfamily_Thioredoxin-like_fold,superfamily_Glutathione-S-Trfase_C-like	-	no_errors	GDAP1	HGNC	ENSG00000104381	140	1	0.71	241	34	12.36	-	-	-
GPR101	0	genome.wustl.edu	37	X	136112380	136112380	+	Missense_Mutation	SNP	G	G	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	X	136112380	136112380	G	C	SNP	GPR101	ENST00000298110	human	ensembl	69_37n	-1	known	missense	c.1454	p.P485R	0.873	NULL	pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfscan_GPCR_Rhodpsn_supfam,prints_7TM_GPCR_Rhodpsn	-	no_errors	GPR101	HGNC	ENSG00000165370	173	0	0.00	114	63	35.59	-	-	-
GYLTL1B	0	genome.wustl.edu	37	11	45948372	45948373	+	Frame_Shift_Ins	INS	-	-	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	11	45948372	45948373	-	C	INS	GYLTL1B	ENST00000325468	human	ensembl	69_37n	+1	known	frame_shift_ins	c.1275_1276	p.R427fs	0.002:0.023	NULL	pfam_Glyco_trans_8	-	no_errors	GYLTL1B	HGNC	ENSG00000165905	18	0	0.00	10	2	16.67	-	-	-
HHEX	0	genome.wustl.edu	37	10	94454508	94454509	+	Frame_Shift_Ins	INS	-	-	CC			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	10	94454508	94454509	-	CC	INS	HHEX	ENST00000282728	human	ensembl	69_37n	+1	known	frame_shift_ins	c.796_797	p.Y266fs	1.000:1.000	NULL	pfam_Homeodomain,superfamily_Homeodomain-like,smart_Homeodomain,pfscan_Homeodomain,prints_Homeobox_metazoa	-	no_errors	HHEX	HGNC	ENSG00000152804	84	0	0.00	60	55	47.83	-	-	-
HIPK2	0	genome.wustl.edu	37	7	139281654	139281654	+	Frame_Shift_Del	DEL	A	A	-			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	7	139281654	139281654	A	-	DEL	HIPK2	ENST00000406875	human	ensembl	69_37n	-1	known	frame_shift_del	c.2526	p.C842fs	0.991	NULL	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	-	no_errors	HIPK2	HGNC	ENSG00000064393	60	0	0.00	32	14	30.43	-	-	-
KIAA0195	0	genome.wustl.edu	37	17	73487171	73487172	+	Frame_Shift_Ins	INS	-	-	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	17	73487171	73487172	-	G	INS	KIAA0195	ENST00000314256	human	ensembl	69_37n	+1	known	frame_shift_ins	c.1170_1171	p.T392fs	0.998:0.997	NULL	pfam_ATPase_P-typ_cation-transptr_C	-	no_errors	KIAA0195	HGNC	ENSG00000177728	19	0	0.00	17	2	10.53	-	-	-
LAMB2	0	genome.wustl.edu	37	3	49158663	49158663	+	Missense_Mutation	SNP	T	T	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	3	49158663	49158663	T	A	SNP	LAMB2	ENST00000305544	human	ensembl	69_37n	-1	known	missense	c.5393	p.Q1798L	1.000	NULL	pfam_EGF_laminin,pfam_Laminin_N,smart_Laminin_N,smart_EGF_laminin,smart_EGF-like,pfscan_Laminin_IV,pfscan_EGF_laminin,pfscan_Laminin_N	-	no_errors	LAMB2	HGNC	ENSG00000172037	19	0	0.00	13	5	26.32	-	-	-
LEKR1	0	genome.wustl.edu	37	3	156763225	156763225	+	Frame_Shift_Del	DEL	A	A	-			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	3	156763225	156763225	A	-	DEL	LEKR1	ENST00000356539	human	ensembl	69_37n	+1	known	frame_shift_del	c.1765	p.S589fs	0.968	NULL	superfamily_Ribosomal_L29	-	no_errors	LEKR1	HGNC	ENSG00000178110	196	0	0.00	66	81	54.00	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56178399	56178400	+	Frame_Shift_Ins	INS	-	-	T			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	5	56178399	56178400	-	T	INS	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.3372_3373	p.N1124fs	1.000:1.000	NULL	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	224	0	0.00	90	31	25.62	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56178400	56178400	+	Missense_Mutation	SNP	A	A	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	5	56178400	56178400	A	G	SNP	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	missense	c.3373	p.N1125D	1.000	NULL	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	226	0	0.00	89	35	28.23	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56189387	56189387	+	Frame_Shift_Del	DEL	C	C	-			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	5	56189387	56189387	C	-	DEL	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_del	c.4419	p.P1474fs	1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	102	0	0.00	76	27	26.21	-	-	-
MLL3	0	genome.wustl.edu	37	7	151904386	151904386	+	Silent	SNP	T	T	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	7	151904386	151904386	T	C	SNP	MLL3	ENST00000355193	human	ensembl	69_37n	-1	known	silent	c.3840	p.P1280	1.000	NULL	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_superfamily,smart_Znf_PHD,smart_Znf_RING,smart_HMG_superfamily,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_DHHC_palmitoyltrfase,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	MLL3	HGNC	ENSG00000055609	488	0	0.00	176	134	43.23	-	-	-
MUC6	0	genome.wustl.edu	37	11	1016078	1016079	+	Frame_Shift_Ins	INS	-	-	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	11	1016078	1016079	-	G	INS	MUC6	ENST00000421673	human	ensembl	69_37n	-1	known	frame_shift_ins	c.6723_6722	p.A2242fs	0.000:0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_Cys_knot_C,pfscan_Cys_knot_C	-	no_errors	MUC6	HGNC	ENSG00000184956	21	0	0.00	21	11	34.38	-	-	-
MYCBP2	0	genome.wustl.edu	37	13	77671946	77671946	+	Missense_Mutation	SNP	T	T	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	13	77671946	77671946	T	C	SNP	MYCBP2	ENST00000407578	human	ensembl	69_37n	-1	known	missense	c.9343	p.I3115V	1.000	superfamily_ARM-type_fold	pfam_PHR,pfam_Reg_chr_condens,pfam_Filamin/ABP280_repeat-like,superfamily_Reg_csome_cond/b-lactamase_inh,superfamily_Galactose-bd-like,superfamily_Ig_E-set,superfamily_ARM-type_fold,smart_Znf_RING,prints_Reg_chr_condens,pfscan_Filamin/ABP280_repeat-like,pfscan_Znf_RING,pfscan_Reg_chr_condens	-	no_errors	MYCBP2	HGNC	ENSG00000005810	195	0	0.00	129	106	44.92	-	-	-
NACA	0	genome.wustl.edu	37	12	57118242	57118242	+	Missense_Mutation	SNP	C	C	T			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	12	57118242	57118242	C	T	SNP	NACA	ENST00000454682	human	ensembl	69_37n	-1	known	missense	c.64	p.E22K	1.000	NULL	pfam_Nas_poly-pep-assoc_cplx,superfamily_UBA-like,pfscan_Nas_poly-pep-assoc_cplx	-	no_errors	NACA	HGNC	ENSG00000196531	32	0	0.00	18	9	33.33	-	-	-
NBPF9	0	genome.wustl.edu	37	1	144827878	144827879	+	In_Frame_Ins	INS	-	-	AGG			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	1	144827878	144827879	-	AGG	INS	NBPF9	ENST00000375552	human	ensembl	69_37n	+1	known	in_frame_ins	c.1757_1758	p.587in_frame_insG	0.025:0.025	NULL	pfam_NBPF_dom	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	NBPF9	HGNC	ENSG00000168614	9	0	0.00	32	5	13.51	-	-	-
PIK3CA	0	genome.wustl.edu	37	3	178936091	178936091	+	Missense_Mutation	SNP	G	G	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	3	178936091	178936091	G	A	SNP	PIK3CA	ENST00000263967	human	ensembl	69_37n	+1	known	missense	c.1633	p.E545K	1.000	pfam_PInositide-3_kin_accessory_dom,superfamily_ARM-type_fold,smart_PInositide-3_kin_accessory_dom	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CA	HGNC	ENSG00000121879	126	0	0.00	72	30	29.41	-	-	-
PIP5K1C	0	genome.wustl.edu	37	19	3656491	3656491	+	Missense_Mutation	SNP	T	T	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	19	3656491	3656491	T	C	SNP	PIP5K1C	ENST00000537021	human	ensembl	69_37n	-1	known	missense	c.533	p.Y178C	1.000	pfam_PInositol-4-P-5-kinase_core,smart_PInositol-4P-5-kinase_core_sub	pfam_PInositol-4-P-5-kinase_core,smart_PInositol-4P-5-kinase_core_sub	-	no_errors	PIP5K1C	HGNC	ENSG00000186111	9	0	0.00	6	6	50.00	-	-	-
POGK	0	genome.wustl.edu	37	1	166810249	166810249	+	Frame_Shift_Del	DEL	A	A	-			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	1	166810249	166810249	A	-	DEL	POGK	ENST00000367875	human	ensembl	69_37n	+1	known	frame_shift_del	c.56	p.E20fs	1.000	NULL	pfam_DDE_SF_endonuclease_CENPB-like,pfam_Brinker_DNA-bd,pfam_HTH_CenpB_DNA-bd_dom,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,superfamily_Homeodomain-like,smart_Krueppel-associated_box,smart_HTH_CenpB_DNA-bd_dom,pfscan_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel	-	no_errors	POGK	HGNC	ENSG00000143157	92	0	0.00	34	38	52.78	-	-	-
POLQ	0	genome.wustl.edu	37	3	121207309	121207309	+	Missense_Mutation	SNP	A	A	G			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	3	121207309	121207309	A	G	SNP	POLQ	ENST00000264233	human	ensembl	69_37n	-1	known	missense	c.4469	p.L1490P	0.993	NULL	pfam_DNA-dir_DNA_pol_A_palm_dom,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_RNaseH-like_dom,smart_Helicase_ATP-bd,smart_Helicase_C,smart_DNA-dir_DNA_pol_A_palm_dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,prints_DNA_polymerase_A	-	no_errors	POLQ	HGNC	ENSG00000051341	229	0	0.00	203	25	10.96	-	-	-
PRICKLE3	0	genome.wustl.edu	37	X	49040116	49040117	+	Frame_Shift_Del	DEL	GT	GT	-			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	GT	GT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	X	49040116	49040117	GT	-	DEL	PRICKLE3	ENST00000536904	human	ensembl	69_37n	-1	known	frame_shift_del	c.179_178	p.T60fs	0.149:0.119	NULL	pfam_Znf_LIM,pfam_PET_domain,smart_Znf_LIM,pfscan_Znf_LIM	-	no_errors	PRICKLE3	HGNC	ENSG00000012211	32	0	0.00	12	3	20.00	-	-	-
PTCHD1	0	genome.wustl.edu	37	X	23412005	23412005	+	Silent	SNP	C	C	T			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	X	23412005	23412005	C	T	SNP	PTCHD1	ENST00000379361	human	ensembl	69_37n	+1	known	silent	c.2370	p.A790	1.000	pfam_Patched	pfam_Patched,pfscan_SSD	-	no_errors	PTCHD1	HGNC	ENSG00000165186	166	0	0.00	150	25	14.29	-	-	-
RAB40C	0	genome.wustl.edu	37	16	677579	677580	+	Frame_Shift_Ins	INS	-	-	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	16	677579	677580	-	C	INS	RAB40C	ENST00000248139	human	ensembl	69_37n	+1	known	frame_shift_ins	c.803_804	p.Q271fs	1.000:1.000	NULL	pfam_Small_GTPase,pfam_MIRO-like,pfam_SOCS_C,pfam_Small_GTPase_ARF/SAR,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,smart_SOCS_C,prints_Small_GTPase,pfscan_SOCS_C,tigrfam_Small_GTP-bd_dom	-	no_errors	RAB40C	HGNC	ENSG00000197562	13	0	0.00	10	3	23.08	-	-	-
SMTNL1	0	genome.wustl.edu	37	11	57311158	57311158	+	Missense_Mutation	SNP	C	C	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	11	57311158	57311158	C	A	SNP	SMTNL1	ENST00000457912	human	ensembl	69_37n	+1	known	missense	c.848	p.A283E	0.446	NULL	pfam_CH-domain,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	-	no_errors	SMTNL1	HGNC	ENSG00000214872	10	0	0.00	9	5	35.71	-	-	-
SUFU	0	genome.wustl.edu	37	10	104356980	104356981	+	Frame_Shift_Ins	INS	-	-	C			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	10	104356980	104356981	-	C	INS	SUFU	ENST00000369902	human	ensembl	69_37n	+1	known	frame_shift_ins	c.840_841	p.E282fs	0.594:1.000	pfam_SUFU_C,pirsf_Suppressor_of_fused_protein	pfam_SUFU_C,pfam_SUFU_domain,pirsf_Suppressor_of_fused_protein	-	no_errors	SUFU	HGNC	ENSG00000107882	57	0	0.00	11	3	21.43	-	-	-
SYNCRIP	0	genome.wustl.edu	37	6	86350199	86350199	+	Nonsense_Mutation	SNP	G	G	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	6	86350199	86350199	G	A	SNP	SYNCRIP	ENST00000369622	human	ensembl	69_37n	-1	known	nonsense	c.232	p.Q78*	1.000	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom,tigrfam_HnRNP_R/Q_splicing_fac	-	no_errors	SYNCRIP	HGNC	ENSG00000135316	220	0	0.00	195	69	26.14	-	-	-
TCF19	0	genome.wustl.edu	37	6	31127397	31127398	+	Frame_Shift_Ins	INS	-	-	A			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	6	31127397	31127398	-	A	INS	TCF19	ENST00000376255	human	ensembl	69_37n	+1	known	frame_shift_ins	c.151_152	p.G51fs	0.800:0.937	pfam_FHA_dom,superfamily_SMAD_FHA_domain,smart_FHA_dom,pfscan_FHA_dom	pfam_FHA_dom,pfam_Znf_PHD-finger,superfamily_SMAD_FHA_domain,superfamily_Znf_FYVE_PHD,smart_FHA_dom,smart_Znf_PHD,pfscan_FHA_dom	-	no_errors	TCF19	HGNC	ENSG00000137310	10	0	0.00	11	3	21.43	-	-	-
TPCN2	0	genome.wustl.edu	37	11	68822752	68822753	+	Frame_Shift_Ins	INS	-	-	CT			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	11	68822752	68822753	-	CT	INS	TPCN2	ENST00000294309	human	ensembl	69_37n	+1	known	frame_shift_ins	c.361_362	p.C122fs	0.999:1.000	NULL	pfam_Ion_trans_dom	-	no_errors	TPCN2	HGNC	ENSG00000162341	52	0	0.00	38	5	11.63	-	-	-
TRIM28	0	genome.wustl.edu	37	19	59061549	59061549	+	Silent	SNP	C	C	T			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	19	59061549	59061549	C	T	SNP	TRIM28	ENST00000253024	human	ensembl	69_37n	+1	known	silent	c.2229	p.I743	0.962	superfamily_Bromodomain,smart_Bromodomain	pfam_Znf_B-box,pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,superfamily_Bromodomain,smart_Znf_RING,smart_Znf_B-box,smart_Bbox_C,smart_Znf_PHD,smart_Bromodomain,pfscan_Znf_B-box,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	TRIM28	HGNC	ENSG00000130726	11	0	0.00	22	21	48.84	-	-	-
UROD	0	genome.wustl.edu	37	1	45478691	45478691	+	Frame_Shift_Del	DEL	G	G	-			TCGA-A8-A06P-01A-11W-A019-09	TCGA-A8-A06P-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	239b3d55-c5d6-4478-9b7b-1cbad3c03c81	f8f99cc8-0355-4bf9-b26e-65603682d0f9	1	45478691	45478691	G	-	DEL	UROD	ENST00000246337	human	ensembl	69_37n	+1	known	frame_shift_del	c.133	p.E45fs	1.000	pfam_Uroporphyrinogen_deCOase,tigrfam_Uroporphyrinogen_deCO2ase_HemE	pfam_Uroporphyrinogen_deCOase,tigrfam_Uroporphyrinogen_deCO2ase_HemE	-	no_errors	UROD	HGNC	ENSG00000126088	42	0	0.00	20	29	59.18	-	-	-
