Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
ACP5	0	genome.wustl.edu	37	19	11686061	11686061	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	11686061	11686061	G	C	SNP	ACP5	ENST00000218758	human	ensembl	69_37n	-1	known	missense	c.742	p.Q248E	0.803	NULL	pfam_Metallo_PEstase_dom	-	no_errors	ACP5	HGNC	ENSG00000102575	33	0	0.00	8	6	42.86	-	-	-
AHNAK	0	genome.wustl.edu	37	11	62288240	62288240	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	11	62288240	62288240	C	G	SNP	AHNAK	ENST00000378024	human	ensembl	69_37n	-1	known	missense	c.13649	p.G4550A	0.066	NULL	superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	AHNAK	HGNC	ENSG00000124942	225	0	0.00	47	19	28.79	-	-	-
ARHGEF6	0	genome.wustl.edu	37	X	135764932	135764932	+	Missense_Mutation	SNP	A	A	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	X	135764932	135764932	A	T	SNP	ARHGEF6	ENST00000250617	human	ensembl	69_37n	-1	known	missense	c.1464	p.S488R	1.000	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_DH-domain,pfam_SH3_2,pfam_SH3_domain,pfam_CH-domain,pfam_Pleckstrin_homology,pfam_CAMSAP_CH,superfamily_DH-domain,superfamily_CH-domain,superfamily_SH3_domain,smart_CH-domain,smart_SH3_domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_CH-domain,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_DH-domain,prints_SH3_domain,prints_SM22_calponin	-	no_errors	ARHGEF6	HGNC	ENSG00000129675	347	0	0.00	86	113	56.50	-	-	-
ARL11	0	genome.wustl.edu	37	13	50204809	50204809	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	13	50204809	50204809	G	A	SNP	ARL11	ENST00000282026	human	ensembl	69_37n	+1	known	missense	c.226	p.D76N	1.000	pfam_Small_GTPase_ARF/SAR,pfam_SRP_receptor_beta_su,pfam_Small_GTPase,pfam_Gtr1_RagA,pfam_MIRO-like,smart_Small_GTPase_SAR1,smart_Small_GTPase_ARF,prints_Small_GTPase_ARF/SAR,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase_ARF/SAR,pfam_SRP_receptor_beta_su,pfam_Small_GTPase,pfam_Gtr1_RagA,pfam_MIRO-like,smart_Small_GTPase_SAR1,smart_Small_GTPase_ARF,prints_Small_GTPase_ARF/SAR,tigrfam_Small_GTP-bd_dom	-	no_errors	ARL11	HGNC	ENSG00000152213	38	0	0.00	10	14	58.33	-	-	-
ATHL1	0	genome.wustl.edu	37	11	290714	290715	+	Frame_Shift_Ins	INS	-	-	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	11	290714	290715	-	G	INS	ATHL1	ENST00000409548	human	ensembl	69_37n	+1	known	frame_shift_ins	c.507_508	p.P171fs	0.850:0.999	NULL	pfam_Glyco_hydro_65_M,superfamily_6-hairpin_glycosidase-like	-	no_errors	ATHL1	HGNC	ENSG00000142102	25	0	0.00	13	3	18.75	-	-	-
ATP1A3	0	genome.wustl.edu	37	19	42482310	42482310	+	Missense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	42482310	42482310	C	T	SNP	ATP1A3	ENST00000545399	human	ensembl	69_37n	-1	known	missense	c.1838	p.G613D	1.000	pfam_Dehalogen-like_hydro,superfamily_HAD-like_dom,prints_ATPase_P-typ_ion-transptr,tigrfam_ATPase_P-typ_cation-ex_asu_euk	pfam_ATPase_P-typ_ATPase-assoc-dom,pfam_ATPase_P-typ_cation-transptr_C,pfam_Dehalogen-like_hydro,pfam_ATPase_P-typ_cation-transptr_N,superfamily_ATPase_cation_domN,superfamily_HAD-like_dom,smart_ATPase_P-typ_cation-transptr_N,prints_ATPase_P-typ_cation-exchng_asu,prints_ATPase_P-typ_ion-transptr,tigrfam_ATPase_P-typ_cation-ex_asu_euk,tigrfam_ATPase_P-typ_ion-transptr	-	no_errors	ATP1A3	HGNC	ENSG00000105409	292	0	0.00	159	89	35.89	-	-	-
BCL9	0	genome.wustl.edu	37	1	147092484	147092487	+	Frame_Shift_Del	DEL	GGGG	GGGG	-			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	GGGG	GGGG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	147092484	147092487	GGGG	-	DEL	BCL9	ENST00000234739	human	ensembl	69_37n	+1	known	frame_shift_del	c.2523_2526	p.R843fs	1.000:1.000:1.000:0.967	NULL	pfam_BCL9_beta-catenin-bd_dom	-	no_errors	BCL9	HGNC	ENSG00000116128	209	0	0.00	158	55	25.35	-	-	-
BCL9	0	genome.wustl.edu	37	1	147092488	147092488	+	Missense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	147092488	147092488	C	T	SNP	BCL9	ENST00000234739	human	ensembl	69_37n	+1	known	missense	c.2527	p.R843W	1.000	NULL	pfam_BCL9_beta-catenin-bd_dom	-	no_errors	BCL9	HGNC	ENSG00000116128	208	0	0.00	152	58	27.62	-	-	-
BPIFA2	0	genome.wustl.edu	37	20	31757009	31757009	+	Missense_Mutation	SNP	T	T	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	20	31757009	31757009	T	C	SNP	BPIFA2	ENST00000253362	human	ensembl	69_37n	+1	known	missense	c.58	p.S20P	0.000	NULL	pfam_Lipid-bd_serum_glycop_N,superfamily_Bactericidal_perm-incr_a/b_dom	-	no_errors	BPIFA2	HGNC	ENSG00000131050	128	0	0.00	73	10	12.05	-	-	-
C12orf55	0	genome.wustl.edu	37	12	97043730	97043733	+	Frame_Shift_Del	DEL	ACAA	ACAA	-			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	ACAA	ACAA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	97043730	97043733	ACAA	-	DEL	C12orf55	ENST00000342887	human	ensembl	69_37n	+1	known	frame_shift_del	c.27_30	p.T11fs	0.000:0.000:0.000:0.000	NULL	NULL	-	no_errors	C12orf55	HGNC	ENSG00000188596	270	0	0.00	85	64	42.95	-	-	-
C1orf54	0	genome.wustl.edu	37	1	150246528	150246528	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	150246528	150246528	G	A	SNP	C1orf54	ENST00000369099	human	ensembl	69_37n	+1	known	missense	c.85	p.E29K	0.024	NULL	NULL	-	no_errors	C1orf54	HGNC	ENSG00000118292	163	0	0.00	106	29	21.48	-	-	-
C20orf26	0	genome.wustl.edu	37	20	20232263	20232263	+	Silent	SNP	T	T	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	20	20232263	20232263	T	C	SNP	C20orf26	ENST00000245957	human	ensembl	69_37n	+1	known	silent	c.2184	p.Y728	0.997	NULL	superfamily_Acyl_CoA_acyltransferase	-	no_errors	C20orf26	HGNC	ENSG00000089101	140	0	0.00	50	36	41.86	-	-	-
C20orf85	0	genome.wustl.edu	37	20	56735726	56735727	+	Frame_Shift_Ins	INS	-	-	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	20	56735726	56735727	-	C	INS	C20orf85	ENST00000371168	human	ensembl	69_37n	+1	known	frame_shift_ins	c.262_263	p.V91fs	0.675:0.687	NULL	NULL	-	no_errors	C20orf85	HGNC	ENSG00000124237	49	0	0.00	34	4	10.53	-	-	-
C7orf62	0	genome.wustl.edu	37	7	88424032	88424032	+	Silent	SNP	T	T	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	7	88424032	88424032	T	A	SNP	C7orf62	ENST00000297203	human	ensembl	69_37n	-1	known	silent	c.225	p.S75	0.000	NULL	NULL	-	no_errors	C7orf62	HGNC	ENSG00000164645	402	0	0.00	140	70	33.33	-	-	-
C9orf43	0	genome.wustl.edu	37	9	116191234	116191234	+	Missense_Mutation	SNP	A	A	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	9	116191234	116191234	A	C	SNP	C9orf43	ENST00000288462	human	ensembl	69_37n	+1	known	missense	c.1162	p.S388R	0.000	NULL	NULL	-	no_errors	C9orf43	HGNC	ENSG00000157653	316	0	0.00	103	53	33.76	-	-	-
CECR1	0	genome.wustl.edu	37	22	17690423	17690424	+	Frame_Shift_Ins	INS	-	-	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	22	17690423	17690424	-	C	INS	CECR1	ENST00000262607	human	ensembl	69_37n	-1	known	frame_shift_ins	c.145_144	p.R48fs	0.036:0.052	pfam_A_deaminase_N,tigrfam_Ad_deam-like	pfam_A/AMP_deaminase_dom,pfam_A_deaminase_N,tigrfam_Ad_deam-like	-	no_errors	CECR1	HGNC	ENSG00000093072	70	0	0.00	41	5	10.87	-	-	-
CES5A	0	genome.wustl.edu	37	16	55903634	55903634	+	Missense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	16	55903634	55903634	C	T	SNP	CES5A	ENST00000521992	human	ensembl	69_37n	-1	known	missense	c.527	p.G176D	1.000	pfam_CarbesteraseB,pfam_AB_hydrolase_3	pfam_CarbesteraseB,pfam_AB_hydrolase_3	-	no_errors	CES5A	HGNC	ENSG00000159398	127	0	0.00	95	39	29.10	-	-	-
CHRM1	0	genome.wustl.edu	37	11	62678402	62678402	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	11	62678402	62678402	C	A	SNP	CHRM1	ENST00000306960	human	ensembl	69_37n	-1	known	missense	c.171	p.K57N	1.000	pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam	pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,prints_Musac_M1_rcpt,prints_Musac_rcpt,prints_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam	-	no_errors	CHRM1	HGNC	ENSG00000168539	365	1	0.27	138	71	33.97	-	-	-
CHRNA1	0	genome.wustl.edu	37	2	175618463	175618463	+	Silent	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	175618463	175618463	G	A	SNP	CHRNA1	ENST00000261007	human	ensembl	69_37n	-1	known	silent	c.621	p.S207	0.323	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd	pfam_Neurotrans-gated_channel_TM,pfam_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,prints_Nicotinic_acetylcholine_rcpt,prints_Neur_channel	-	no_errors	CHRNA1	HGNC	ENSG00000138435	226	0	0.00	79	58	42.34	-	-	-
CLUL1	0	genome.wustl.edu	37	18	618071	618071	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	18	618071	618071	G	C	SNP	CLUL1	ENST00000338387	human	ensembl	69_37n	+1	known	missense	c.71	p.W24S	0.982	pfam_Clusterin-like	pfam_Clusterin-like,smart_Clusterin_N,smart_Clusterin_C	-	no_errors	CLUL1	HGNC	ENSG00000079101	280	0	0.00	204	83	28.92	-	-	-
CNTLN	0	genome.wustl.edu	37	9	17409379	17409379	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	9	17409379	17409379	G	C	SNP	CNTLN	ENST00000380647	human	ensembl	69_37n	+1	known	missense	c.2704	p.D902H	0.945	NULL	superfamily_Prefoldin	-	no_errors	CNTLN	HGNC	ENSG00000044459	178	0	0.00	39	87	69.05	-	-	-
COL19A1	0	genome.wustl.edu	37	6	70610189	70610189	+	Silent	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	6	70610189	70610189	C	G	SNP	COL19A1	ENST00000322773	human	ensembl	69_37n	+1	known	silent	c.225	p.T75	0.962	superfamily_ConA-like_lec_gl,smart_Laminin_G	pfam_Collagen,superfamily_ConA-like_lec_gl,smart_Laminin_G	-	no_errors	COL19A1	HGNC	ENSG00000082293	205	0	0.00	25	7	21.88	-	-	-
COX15	0	genome.wustl.edu	37	10	101483877	101483877	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	10	101483877	101483877	G	C	SNP	COX15	ENST00000016171	human	ensembl	69_37n	-1	known	missense	c.586	p.L196V	1.000	pfam_HemeA_syn	pfam_HemeA_syn,superfamily_Pept_cys/ser_Trypsin-like	-	no_errors	COX15	HGNC	ENSG00000014919	243	0	0.00	125	39	23.64	-	-	-
CYP2D6	0	genome.wustl.edu	37	22	42525144	42525145	+	Frame_Shift_Ins	INS	-	-	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	22	42525144	42525145	-	T	INS	CYP2D6	ENST00000360608	human	ensembl	69_37n	-1	known	frame_shift_ins	c.396_395	p.R133fs	0.995:1.000	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_E_grp-I_CYP2D-like,prints_Cyt_P450,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450_B	-	no_errors	CYP2D6	HGNC	ENSG00000100197	106	0	0.00	13	26	66.67	-	-	-
DIO1	0	genome.wustl.edu	37	1	54371907	54371907	+	Silent	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	54371907	54371907	G	A	SNP	DIO1	ENST00000388876	human	ensembl	69_37n	+1	known	silent	c.477	p.Q159	0.095	pfam_Iodothyronine_deiodinase	pfam_Iodothyronine_deiodinase	-	no_errors	DIO1	HGNC	ENSG00000211452	66	0	0.00	63	25	28.41	-	-	-
DNAH9	0	genome.wustl.edu	37	17	11520810	11520810	+	Silent	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	17	11520810	11520810	G	A	SNP	DNAH9	ENST00000262442	human	ensembl	69_37n	+1	known	silent	c.987	p.P329	0.000	pfam_Dynein_heavy_dom-1	pfam_Dynein_heavy,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,smart_AAA+_ATPase	-	no_errors	DNAH9	HGNC	ENSG00000007174	68	0	0.00	22	36	62.07	-	-	-
DSEL	0	genome.wustl.edu	37	18	65178887	65178887	+	Frame_Shift_Del	DEL	C	C	-			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	18	65178887	65178887	C	-	DEL	DSEL	ENST00000310045	human	ensembl	69_37n	-1	known	frame_shift_del	c.2989	p.A997fs	1.000	pfam_Sulfotransferase_dom	pfam_Sulfotransferase_dom,superfamily_Chondroitin_lyas	-	no_errors	DSEL	HGNC	ENSG00000171451	64	0	0.00	11	2	15.38	-	-	-
EIF2AK1	0	genome.wustl.edu	37	7	6077156	6077156	+	Splice_Site	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	7	6077156	6077156	C	T	SNP	EIF2AK1	ENST00000199389	human	ensembl	69_37n	-1	known	splice_site	c.1232-1	e11-1	1.000	-	-	-	no_errors	EIF2AK1	HGNC	ENSG00000086232	160	0	0.00	61	26	29.89	-	-	-
EMR1	0	genome.wustl.edu	37	19	6926403	6926403	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	6926403	6926403	C	A	SNP	EMR1	ENST00000312053	human	ensembl	69_37n	+1	known	missense	c.2013	p.F671L	0.083	pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	pfam_GPCR_2_secretin-like,pfam_EGF-like_Ca-bd,pfam_GPS_dom,smart_EGF-like_Ca-bd,smart_EGF-like,smart_GPS_dom,pfscan_EG-like_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_EMR1_rcpt,prints_GPCR_2_secretin-like	-	no_errors	EMR1	HGNC	ENSG00000174837	543	0	0.00	263	173	39.68	-	-	-
EPS8L1	0	genome.wustl.edu	37	19	55598949	55598949	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	55598949	55598949	G	C	SNP	EPS8L1	ENST00000201647	human	ensembl	69_37n	+1	known	missense	c.2139	p.K713N	1.000	NULL	pfam_PTB,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_SAM/pointed,smart_PTyr_interaction_dom,smart_SH3_domain,pfscan_SH3_domain	-	no_errors	EPS8L1	HGNC	ENSG00000131037	750	1	0.13	340	99	22.55	-	-	-
FAM157B	0	genome.wustl.edu	37	9	141107536	141107537	+	RNA	INS	-	-	GCA			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	9	141107536	141107537	-	GCA	INS	FAM157B	ENST00000446912	human	ensembl	69_37n	+1	known	rna	NULL	NULL	0.033:0.036	-	-	-	no_errors	FAM157B	HGNC	ENSG00000233013	94	0	0.00	43	10	18.87	-	-	-
FAM53B	0	genome.wustl.edu	37	10	126370497	126370497	+	Nonsense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	10	126370497	126370497	G	T	SNP	FAM53B	ENST00000337318	human	ensembl	69_37n	-1	known	nonsense	c.585	p.C195*	0.996	NULL	NULL	-	no_errors	FAM53B	HGNC	ENSG00000189319	46	0	0.00	19	9	32.14	-	-	-
FAM5C	0	genome.wustl.edu	37	1	190068109	190068109	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	190068109	190068109	G	A	SNP	FAM5C	ENST00000367462	human	ensembl	69_37n	-1	known	missense	c.1340	p.S447F	0.143	NULL	pfam_MACPF,smart_MACPF	-	no_errors	FAM5C	HGNC	ENSG00000162670	58	0	0.00	33	13	28.26	-	-	-
FAM90A1	0	genome.wustl.edu	37	12	8376138	8376138	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	8376138	8376138	C	A	SNP	FAM90A1	ENST00000307435	human	ensembl	69_37n	-1	known	missense	c.339	p.Q113H	0.000	NULL	NULL	-	no_errors	FAM90A1	HGNC	ENSG00000171847	66	0	0.00	18	15	45.45	-	-	-
FBXO21	0	genome.wustl.edu	37	12	117604733	117604733	+	Missense_Mutation	SNP	A	A	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	117604733	117604733	A	G	SNP	FBXO21	ENST00000330622	human	ensembl	69_37n	-1	known	missense	c.1163	p.M388T	1.000	superfamily_F-box_dom_cyclin-like	pfam_Hemimethylated_DNA-bd_dom,superfamily_Hemimethylated_DNA-bd_dom,superfamily_F-box_dom_cyclin-like,tigrfam_Hemimethylated_DNA-bd_dom	-	no_errors	FBXO21	HGNC	ENSG00000135108	360	0	0.00	107	49	31.41	-	-	-
FRMD6	0	genome.wustl.edu	37	14	52186813	52186813	+	Silent	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	14	52186813	52186813	G	C	SNP	FRMD6	ENST00000344768	human	ensembl	69_37n	+1	known	silent	c.1065	p.L355	1.000	NULL	pfam_FERM_central,pfam_FERM_PH-like_C,pfam_FERM_N,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain	-	no_errors	FRMD6	HGNC	ENSG00000139926	72	0	0.00	23	22	48.89	-	-	-
FXR1	0	genome.wustl.edu	37	3	180675642	180675642	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	3	180675642	180675642	G	C	SNP	FXR1	ENST00000357559	human	ensembl	69_37n	+1	known	missense	c.916	p.E306Q	1.000	pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1	pfam_Frag_X_MRP_fam,pfam_KH_dom_type_1,pfam_Agenet,superfamily_NA-bd_OB-fold-like,smart_KH_dom,pfscan_KH_dom_type_1	-	no_errors	FXR1	HGNC	ENSG00000114416	437	0	0.00	314	68	17.80	-	-	-
GJB5	0	genome.wustl.edu	37	1	35223621	35223621	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	35223621	35223621	C	A	SNP	GJB5	ENST00000338513	human	ensembl	69_37n	+1	known	missense	c.690	p.H230Q	0.000	NULL	pfam_Connexin_N,pfam_Connexin_CCC,smart_Connexin_N,prints_Connexin,prints_Connexin311	-	no_errors	GJB5	HGNC	ENSG00000189280	121	0	0.00	88	30	25.42	-	-	-
GOLGA8J	0	genome.wustl.edu	37	15	30435851	30435851	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	15	30435851	30435851	G	A	SNP	GOLGA8J	ENST00000569052	human	ensembl	69_37n	+1	novel	missense	c.1243	p.A415T	0.955	NULL	NULL	-	no_errors	RP5-1086D14.3	Clone_based_vega_gene	ENSG00000261247	20	0	0.00	7	5	41.67	-	-	-
HIVEP3	0	genome.wustl.edu	37	1	42046159	42046159	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	42046159	42046159	C	A	SNP	HIVEP3	ENST00000247584	human	ensembl	69_37n	-1	known	missense	c.4310	p.S1437I	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	HIVEP3	HGNC	ENSG00000127124	161	0	0.00	40	43	51.81	-	-	-
IFNE	0	genome.wustl.edu	37	9	21481513	21481513	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	9	21481513	21481513	G	C	SNP	IFNE	ENST00000448696	human	ensembl	69_37n	-1	known	missense	c.181	p.L61V	0.004	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta,prints_Interferon_alpha/beta/delta	pfam_Interferon_alpha/beta/delta,superfamily_4_helix_cytokine-like_core,smart_Interferon_alpha/beta/delta,prints_Interferon_alpha/beta/delta	-	no_errors	IFNE	HGNC	ENSG00000184995	182	0	0.00	82	37	31.09	-	-	-
IGKV1-5	0	genome.wustl.edu	37	2	89246827	89246827	+	Missense_Mutation	SNP	T	T	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	89246827	89246827	T	G	SNP	IGKV1-5	ENST00000496168	human	ensembl	69_37n	-1	known	missense	c.343	p.S115R	0.011	pfam_Ig_V-set,pfam_Ig_I-set,smart_Ig_sub,pfscan_Ig-like	pfam_Ig_V-set,pfam_Ig_I-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like	-	no_stop_codon	IGKV1-5	HGNC	ENSG00000243466	311	0	0.00	139	47	25.27	-	-	-
INTS3	0	genome.wustl.edu	37	1	153734075	153734075	+	Missense_Mutation	SNP	A	A	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	153734075	153734075	A	T	SNP	INTS3	ENST00000318967	human	ensembl	69_37n	+1	known	missense	c.1439	p.K480M	1.000	pfam_Integrator_3	pfam_Integrator_3	-	no_errors	INTS3	HGNC	ENSG00000143624	200	0	0.00	96	35	26.72	-	-	-
KIAA1383	0	genome.wustl.edu	37	1	232942237	232942237	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	232942237	232942237	C	G	SNP	KIAA1383	ENST00000418460	human	ensembl	69_37n	+1	known	missense	c.1468	p.H490D	0.000	NULL	NULL	-	no_errors	KIAA1383	HGNC	ENSG00000212916	133	0	0.00	47	14	22.95	-	-	-
KLHDC3	0	genome.wustl.edu	37	6	42986630	42986630	+	Missense_Mutation	SNP	A	A	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	6	42986630	42986630	A	C	SNP	KLHDC3	ENST00000326974	human	ensembl	69_37n	+1	known	missense	c.850	p.K284Q	1.000	NULL	pfam_Kelch_2,pfam_Kelch_1	-	no_errors	KLHDC3	HGNC	ENSG00000124702	113	0	0.00	46	12	20.69	-	-	-
KRT19	0	genome.wustl.edu	37	17	39680125	39680125	+	Missense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	17	39680125	39680125	C	T	SNP	KRT19	ENST00000361566	human	ensembl	69_37n	-1	known	missense	c.1073	p.R358Q	1.000	pfam_F	pfam_F,superfamily_Prefoldin,prints_Keratin_I	-	no_errors	KRT19	HGNC	ENSG00000171345	53	0	0.00	19	6	24.00	-	-	-
KRT4	0	genome.wustl.edu	37	12	53208015	53208015	+	Missense_Mutation	SNP	T	T	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	53208015	53208015	T	C	SNP	KRT4	ENST00000293774	human	ensembl	69_37n	-1	known	missense	c.50	p.D17G	0.996	NULL	pfam_F,superfamily_Prefoldin,prints_Keratin_II,prints_Keratin_I	-	no_errors	KRT4	HGNC	ENSG00000170477	71	0	0.00	19	17	47.22	-	-	-
LAMA2	0	genome.wustl.edu	37	6	129824389	129824389	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	6	129824389	129824389	G	C	SNP	LAMA2	ENST00000421865	human	ensembl	69_37n	+1	known	missense	c.8511	p.M2837I	1.000	pfam_Laminin_G,superfamily_ConA-like_lec_gl,smart_Laminin_G,pfscan_Laminin_G	pfam_Laminin_G,pfam_EGF_laminin,pfam_Laminin_N,pfam_Laminin_I,pfam_Laminin_B_type_IV,pfam_Laminin_II,superfamily_ConA-like_lec_gl,superfamily_Galactose-bd-like,superfamily_t-SNARE,smart_Laminin_N,smart_EGF_laminin,smart_EGF-like,smart_Laminin_B_subgr,smart_Laminin_G,pfscan_Laminin_B_type_IV,pfscan_EGF_laminin,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	LAMA2	HGNC	ENSG00000196569	121	0	0.00	62	51	45.13	-	-	-
LOC100996465	0	genome.wustl.edu	37	X	153149672	153149672	+	Missense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	X	153149672	153149672	G	T	SNP	LOC100996465	ENST00000452593	human	ensembl	69_37n	+1	putative	missense	c.503	p.W168L	0.000	NULL	NULL	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	U52112.12	Clone_based_vega_gene	ENSG00000196987	77	0	0.00	28	21	42.86	-	-	-
LRP1B	0	genome.wustl.edu	37	2	141528484	141528484	+	Silent	SNP	T	T	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	141528484	141528484	T	C	SNP	LRP1B	ENST00000389484	human	ensembl	69_37n	-1	known	silent	c.5592	p.G1864	0.987	smart_EGF-like	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,pfam_EGF-like_dom,superfamily_Growth_fac_rcpt,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EGF-like,smart_EGF-like_Ca-bd,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt	-	no_errors	LRP1B	HGNC	ENSG00000168702	185	0	0.00	17	21	55.26	-	-	-
LRRC4B	0	genome.wustl.edu	37	19	51021546	51021546	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	51021546	51021546	C	A	SNP	LRRC4B	ENST00000389201	human	ensembl	69_37n	-1	known	missense	c.1424	p.G475V	0.001	NULL	pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	-	no_errors	LRRC4B	HGNC	ENSG00000131409	20	0	0.00	5	10	66.67	-	-	-
LTBP4	0	genome.wustl.edu	37	19	41133242	41133242	+	Nonsense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	41133242	41133242	G	T	SNP	LTBP4	ENST00000308370	human	ensembl	69_37n	+1	known	nonsense	c.4546	p.E1516*	0.043	NULL	pfam_EGF-like_Ca-bd,pfam_TB_dom,superfamily_TB_dom,smart_EGF-like,smart_EGF-like_Ca-bd,pfscan_EG-like_dom	-	no_errors	LTBP4	HGNC	ENSG00000090006	27	0	0.00	14	6	30.00	-	-	-
MED16	0	genome.wustl.edu	37	19	884973	884973	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	884973	884973	G	C	SNP	MED16	ENST00000325464	human	ensembl	69_37n	-1	known	missense	c.915	p.I305M	0.384	pfam_Mediator_Med16,superfamily_WD40_repeat_dom	pfam_Mediator_Med16,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	MED16	HGNC	ENSG00000175221	8	0	0.00	7	6	46.15	-	-	-
MPHOSPH9	0	genome.wustl.edu	37	12	123703035	123703035	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	123703035	123703035	G	A	SNP	MPHOSPH9	ENST00000541076	human	ensembl	69_37n	-1	known	missense	c.428	p.T143I	1.000	NULL	superfamily_Prefoldin	-	no_errors	MPHOSPH9	HGNC	ENSG00000051825	288	0	0.00	62	108	63.53	-	-	-
MRPL48	0	genome.wustl.edu	37	11	73574260	73574260	+	Missense_Mutation	SNP	T	T	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	11	73574260	73574260	T	A	SNP	MRPL48	ENST00000310614	human	ensembl	69_37n	+1	known	missense	c.518	p.I173K	1.000	pfam_Ribosomal_S10,superfamily_Ribosomal_S10	pfam_Ribosomal_S10,superfamily_Ribosomal_S10	-	no_errors	MRPL48	HGNC	ENSG00000175581	167	0	0.00	30	60	65.93	-	-	-
MYO10	0	genome.wustl.edu	37	5	16818206	16818206	+	Missense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	5	16818206	16818206	C	T	SNP	MYO10	ENST00000513610	human	ensembl	69_37n	-1	known	missense	c.191	p.G64D	0.999	smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_MyTH4_dom,pfam_Pleckstrin_homology,pfam_FERM_central,pfam_IQ_motif_EF-hand-BS,pfam_Ras-assoc,superfamily_FERM_central,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,smart_Pleckstrin_homology,smart_MyTH4_dom,smart_Band_41_domain,pfscan_FERM_domain,pfscan_IQ_motif_EF-hand-BS,pfscan_MyTH4_dom,pfscan_Pleckstrin_homology,prints_Myosin_head_motor_dom	-	no_errors	MYO10	HGNC	ENSG00000145555	156	0	0.00	47	39	45.35	-	-	-
NAP1L1	0	genome.wustl.edu	37	12	76453633	76453633	+	Missense_Mutation	SNP	T	T	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	76453633	76453633	T	A	SNP	NAP1L1	ENST00000261182	human	ensembl	69_37n	-1	known	missense	c.374	p.Y125F	1.000	pfam_NAP_family	pfam_NAP_family	-	no_errors	NAP1L1	HGNC	ENSG00000187109	208	0	0.00	79	15	15.96	-	-	-
NGLY1	0	genome.wustl.edu	37	3	25761640	25761640	+	Missense_Mutation	SNP	A	A	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	3	25761640	25761640	A	G	SNP	NGLY1	ENST00000280700	human	ensembl	69_37n	-1	known	missense	c.1654	p.S552P	1.000	pfam_Peptide_N_glycanase_PAW_dom,superfamily_Galactose-bd-like,smart_Peptide_N_glycanase_PAW_dom	pfam_PUB_domain,pfam_Transglutaminase-like,pfam_Rad4/PNGase_transGLS-fold,pfam_Peptide_N_glycanase_PAW_dom,superfamily_Galactose-bd-like,smart_PUG-dom,smart_Transglutaminase-like,smart_Peptide_N_glycanase_PAW_dom	-	no_errors	NGLY1	HGNC	ENSG00000151092	241	0	0.00	118	59	33.33	-	-	-
NID1	0	genome.wustl.edu	37	1	236205393	236205393	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	236205393	236205393	G	C	SNP	NID1	ENST00000264187	human	ensembl	69_37n	-1	known	missense	c.952	p.L318V	0.000	NULL	pfam_G2_nidogen/fibulin_G2F,pfam_LDLR_classB_rpt,pfam_Nidogen_extracell_dom,pfam_Thyroglobulin_1,pfam_EGF-like_Ca-bd,superfamily_Green_fluorescent_prot-like,superfamily_Thyroglobulin_1,smart_Nidogen_extracell_dom,smart_EGF-like_Ca-bd,smart_EGF-like,smart_G2_nidogen/fibulin_G2F,smart_Thyroglobulin_1,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDLR_classB_rpt,pfscan_G2_nidogen/fibulin_G2F,pfscan_Thyroglobulin_1	-	no_errors	NID1	HGNC	ENSG00000116962	71	0	0.00	40	14	25.93	-	-	-
NR1D2	0	genome.wustl.edu	37	3	24018854	24018854	+	Nonsense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	3	24018854	24018854	C	T	SNP	NR1D2	ENST00000312521	human	ensembl	69_37n	+1	known	nonsense	c.1684	p.R562*	1.000	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt	pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	NR1D2	HGNC	ENSG00000174738	195	0	0.00	26	51	66.23	-	-	-
NR4A3	0	genome.wustl.edu	37	9	102590381	102590381	+	Silent	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	9	102590381	102590381	G	A	SNP	NR4A3	ENST00000330847	human	ensembl	69_37n	+1	known	silent	c.90	p.A30	0.419	NULL	pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_NOR1_rcpt,prints_Nuc_orph_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_Retinoic_acid_rcpt	-	no_errors	NR4A3	HGNC	ENSG00000119508	104	0	0.00	56	29	34.12	-	-	-
NSUN4	0	genome.wustl.edu	37	1	46818635	46818635	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	46818635	46818635	C	G	SNP	NSUN4	ENST00000474844	human	ensembl	69_37n	+1	known	missense	c.688	p.Q230E	0.002	pfam_Fmu/NOL1/Nop2p	pfam_Fmu/NOL1/Nop2p,prints_RCMT	-	no_errors	NSUN4	HGNC	ENSG00000117481	379	0	0.00	229	85	26.98	-	-	-
NXF3	0	genome.wustl.edu	37	X	102332671	102332671	+	Missense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	X	102332671	102332671	C	T	SNP	NXF3	ENST00000427570	human	ensembl	69_37n	-1	known	missense	c.1073	p.C358Y	0.200	NULL	pfam_Tap_RNA-bd,pfam_NTF2,pfscan_Nuclear_transport_factor_2_euk	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	NXF3	HGNC	ENSG00000147206	105	0	0.00	26	31	54.39	-	-	-
OBSCN	0	genome.wustl.edu	37	1	228467646	228467646	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	228467646	228467646	C	G	SNP	OBSCN	ENST00000366706	human	ensembl	69_37n	+1	novel	missense	c.794	p.P265R	0.004	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	-	pseudogene:no_stop_codon:bad_bp_length_for_coding_region	OBSCN	HGNC	ENSG00000154358	52	0	0.00	20	6	23.08	-	-	-
OR10H4	0	genome.wustl.edu	37	19	16060433	16060433	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	16060433	16060433	G	A	SNP	OR10H4	ENST00000322107	human	ensembl	69_37n	+1	known	missense	c.616	p.V206I	0.002	pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_7TM_GPCR_Rhodpsn	pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn	-	no_errors	OR10H4	HGNC	ENSG00000176231	585	0	0.00	414	184	30.67	-	-	-
OR51B4	0	genome.wustl.edu	37	11	5322935	5322935	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	11	5322935	5322935	C	A	SNP	OR51B4	ENST00000380224	human	ensembl	69_37n	-1	known	missense	c.242	p.G81V	0.008	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn	-	no_errors	OR51B4	HGNC	ENSG00000183251	312	0	0.00	172	86	33.33	-	-	-
OR52A5	0	genome.wustl.edu	37	11	5153708	5153708	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	11	5153708	5153708	G	C	SNP	OR52A5	ENST00000307388	human	ensembl	69_37n	-1	known	missense	c.165	p.N55K	0.000	pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam	pfam_7TM_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn	-	no_errors	OR52A5	HGNC	ENSG00000171944	127	0	0.00	45	30	40.00	-	-	-
OR5H15	0	genome.wustl.edu	37	3	97887843	97887844	+	Frame_Shift_Ins	INS	-	-	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	3	97887843	97887844	-	T	INS	OR5H15	ENST00000356526	human	ensembl	69_37n	+1	known	frame_shift_ins	c.300_301	p.S102fs	0.003:0.000	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn	-	no_errors	OR5H15	HGNC	ENSG00000233412	374	0	0.00	207	54	20.69	-	-	-
PI16	0	genome.wustl.edu	37	6	36931628	36931628	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	6	36931628	36931628	G	C	SNP	PI16	ENST00000373674	human	ensembl	69_37n	+1	known	missense	c.1300	p.V434L	0.000	NULL	pfam_CAP_domain,superfamily_CAP_domain,smart_Allrgn_V5/Tpx1,prints_Allrgn_V5/Tpx1	-	no_errors	PI16	HGNC	ENSG00000164530	137	0	0.00	44	19	30.16	-	-	-
PIK3C2B	0	genome.wustl.edu	37	1	204403609	204403609	+	Missense_Mutation	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	204403609	204403609	C	T	SNP	PIK3C2B	ENST00000367187	human	ensembl	69_37n	-1	known	missense	c.3644	p.G1215D	1.000	pfam_PI3/4_kinase_cat_dom,superfamily_Kinase-like_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	pfam_PI3/4_kinase_cat_dom,pfam_PInositide-3_kin_accessory_dom,pfam_PI3K_C2_dom,pfam_PI3K_Ras-bd_dom,pfam_Phox,pfam_C2_Ca-dep,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,superfamily_Phox,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,smart_Phox,smart_C2_Ca-dep,pfscan_C2_membr_targeting,pfscan_Phox,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3C2B	HGNC	ENSG00000133056	177	0	0.00	79	40	33.61	-	-	-
PLK4	0	genome.wustl.edu	37	4	128804612	128804612	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	4	128804612	128804612	G	C	SNP	PLK4	ENST00000270861	human	ensembl	69_37n	+1	known	missense	c.241	p.D81H	1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_POLO_box_duplicated_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_POLO_box_duplicated_dom,pfscan_Prot_kinase_cat_dom	-	no_errors	PLK4	HGNC	ENSG00000142731	147	0	0.00	15	7	31.82	-	-	-
POTEJ	0	genome.wustl.edu	37	2	131414398	131414399	+	Frame_Shift_Ins	INS	-	-	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	131414398	131414399	-	C	INS	POTEJ	ENST00000409602	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.2065_2066	p.R691fs	1.000:1.000	pfam_Actin-like,smart_Actin-like,prints_Actin-like	pfam_Actin-like,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Actin-like,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Actin-like	-	no_errors	POTEJ	HGNC	ENSG00000222038	30	0	0.00	16	2	11.11	-	-	-
PRKCB	0	genome.wustl.edu	37	16	24183606	24183606	+	Missense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	16	24183606	24183606	G	T	SNP	PRKCB	ENST00000303531	human	ensembl	69_37n	+1	known	missense	c.1255	p.V419L	1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pirsf_Protein_kinase_C_a/b/g,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_C2_Ca-dep,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_C2_Ca-dep,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pirsf_Protein_kinase_C_a/b/g,prints_DAG/PE-bd,prints_C2_dom,pfscan_C2_membr_targeting,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_cat_dom	-	no_errors	PRKCB	HGNC	ENSG00000166501	355	2	0.56	195	80	29.09	-	-	-
PTPN18	0	genome.wustl.edu	37	2	131128528	131128530	+	In_Frame_Del	DEL	CAT	CAT	-			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	CAT	CAT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	131128528	131128530	CAT	-	DEL	PTPN18	ENST00000175756	human	ensembl	69_37n	+1	known	in_frame_del	c.915_917	p.I306in_frame_del	0.996:0.995:1.000	NULL	pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Tyr/Dual-specificity_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPN18	HGNC	ENSG00000072135	126	0	0.00	44	27	36.99	-	-	-
PVRL2	0	genome.wustl.edu	37	19	45368575	45368575	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	45368575	45368575	C	G	SNP	PVRL2	ENST00000252483	human	ensembl	69_37n	+1	known	missense	c.136	p.L46V	0.353	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like	pfam_CD80_C2-set,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like	-	no_errors	PVRL2	HGNC	ENSG00000130202	67	0	0.00	37	15	28.85	-	-	-
RANBP17	0	genome.wustl.edu	37	5	170597134	170597134	+	Missense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	5	170597134	170597134	G	T	SNP	RANBP17	ENST00000523189	human	ensembl	69_37n	+1	known	missense	c.1711	p.V571L	1.000	superfamily_ARM-type_fold	pfam_Importin-beta_N,superfamily_ARM-type_fold,smart_Importin-beta_N	-	no_errors	RANBP17	HGNC	ENSG00000204764	713	1	0.14	113	31	21.53	-	-	-
RASSF5	0	genome.wustl.edu	37	1	206760274	206760274	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	206760274	206760274	G	C	SNP	RASSF5	ENST00000355294	human	ensembl	69_37n	+1	known	missense	c.1221	p.E407D	0.990	pfscan_SARAH	pfam_Ras-assoc,pfam_Prot_Kinase_C-like_PE/DAG-bd,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Ras-assoc,pfscan_Ras-assoc,pfscan_SARAH,pfscan_Prot_Kinase_C-like_PE/DAG-bd	-	no_errors	RASSF5	HGNC	ENSG00000136653	351	0	0.00	74	50	40.32	-	-	-
RHOB	0	genome.wustl.edu	37	2	20647263	20647263	+	Missense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	20647263	20647263	G	T	SNP	RHOB	ENST00000272233	human	ensembl	69_37n	+1	known	missense	c.37	p.D13Y	1.000	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_ProtSyn_GTP-bd,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	-	no_errors	RHOB	HGNC	ENSG00000143878	37	0	0.00	28	11	28.21	-	-	-
SCARB1	0	genome.wustl.edu	37	12	125296490	125296490	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	125296490	125296490	G	A	SNP	SCARB1	ENST00000415380	human	ensembl	69_37n	-1	known	missense	c.652	p.L218F	0.134	pfam_CD36	pfam_CD36,prints_CD36,prints_CD36_antigen	-	no_errors	SCARB1	HGNC	ENSG00000073060	250	0	0.00	38	62	62.00	-	-	-
SCARB2	0	genome.wustl.edu	37	4	77100835	77100835	+	Silent	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	4	77100835	77100835	C	T	SNP	SCARB2	ENST00000264896	human	ensembl	69_37n	-1	known	silent	c.447	p.V149	0.000	pfam_CD36	pfam_CD36,superfamily_NA-bd_OB-fold-like,prints_LimpII,prints_CD36,prints_CD36_antigen	-	no_errors	SCARB2	HGNC	ENSG00000138760	96	0	0.00	21	40	65.57	-	-	-
SCLT1	0	genome.wustl.edu	37	4	129873937	129873937	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	4	129873937	129873937	G	A	SNP	SCLT1	ENST00000281142	human	ensembl	69_37n	-1	known	missense	c.1205	p.S402L	1.000	NULL	NULL	-	no_errors	SCLT1	HGNC	ENSG00000151466	301	0	0.00	82	14	14.58	-	-	-
SCN8A	0	genome.wustl.edu	37	12	52182482	52182482	+	Missense_Mutation	SNP	A	A	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	52182482	52182482	A	C	SNP	SCN8A	ENST00000354534	human	ensembl	69_37n	+1	known	missense	c.4231	p.T1411P	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,pfam_IQ_motif_EF-hand-BS,smart_IQ_motif_EF-hand-BS,prints_Na_channel_a8su,prints_Na_channel_asu,prints_PKD_2,pfscan_IQ_motif_EF-hand-BS	-	no_errors	SCN8A	HGNC	ENSG00000196876	126	0	0.00	22	31	58.49	-	-	-
SEZ6L	0	genome.wustl.edu	37	22	26689012	26689012	+	Missense_Mutation	SNP	A	A	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	22	26689012	26689012	A	T	SNP	SEZ6L	ENST00000248933	human	ensembl	69_37n	+1	known	missense	c.735	p.K245N	0.045	NULL	pfam_CUB,pfam_Sushi_SCR_CCP,superfamily_CUB,superfamily_Complement_control_module,smart_CUB,smart_Sushi_SCR_CCP,pfscan_CUB,pfscan_Sushi_SCR_CCP	-	no_errors	SEZ6L	HGNC	ENSG00000100095	162	0	0.00	49	53	51.96	-	-	-
SIRPB1	0	genome.wustl.edu	37	20	1600536	1600536	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	20	1600536	1600536	G	C	SNP	SIRPB1	ENST00000279477	human	ensembl	69_37n	-1	known	missense	c.55	p.L19V	0.008	pfscan_Ig-like	pfam_Ig_C1-set,pfam_CD80_C2-set,pfam_Ig_V-set,pfam_Ig_I-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Ig_C1-set,pfscan_Ig-like	-	no_errors	SIRPB1	HGNC	ENSG00000101307	263	0	0.00	146	87	37.34	-	-	-
SLC12A5	0	genome.wustl.edu	37	20	44669237	44669237	+	Missense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	20	44669237	44669237	G	T	SNP	SLC12A5	ENST00000454036	human	ensembl	69_37n	+1	known	missense	c.907	p.D303Y	1.000	prints_KCL_cotranspt,tigrfam_Na/K/Cl_cotransptS	pfam_AA-permease_dom,prints_KCL_cotranspt,tigrfam_Na/K/Cl_cotransptS	-	no_errors	SLC12A5	HGNC	ENSG00000124140	124	0	0.00	55	27	32.93	-	-	-
SLC45A4	0	genome.wustl.edu	37	8	142222615	142222615	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	8	142222615	142222615	C	G	SNP	SLC45A4	ENST00000517878	human	ensembl	69_37n	-1	known	missense	c.1982	p.G661A	1.000	superfamily_MFS_dom_general_subst_transpt	superfamily_MFS_dom_general_subst_transpt	-	no_errors	SLC45A4	HGNC	ENSG00000022567	87	0	0.00	23	12	33.33	-	-	-
SNN	0	genome.wustl.edu	37	16	11770041	11770041	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	16	11770041	11770041	C	G	SNP	SNN	ENST00000329565	human	ensembl	69_37n	+1	known	missense	c.126	p.S42R	1.000	pfam_SNN_linker	pfam_SNN_transmemb,pfam_SNN_linker,pfam_SNN_cytoplasm	-	no_errors	SNN	HGNC	ENSG00000184602	102	0	0.00	39	19	32.76	-	-	-
SNX13	0	genome.wustl.edu	37	7	17915306	17915306	+	Missense_Mutation	SNP	T	T	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	7	17915306	17915306	T	A	SNP	SNX13	ENST00000428135	human	ensembl	69_37n	-1	novel	missense	c.548	p.D183V	1.000	pfam_Phox_assoc,superfamily_Cyt_c_oxidase_su5A/6,smart_PX_assoc_Snx13,pfscan_Phox_assoc	pfam_Phox_assoc,pfam_Sorting_nexin_C,pfam_Phox,pfam_Regulat_G_prot_signal,superfamily_Regulat_G_prot_signal_superfam,superfamily_Phox,superfamily_Cyt_c_oxidase_su5A/6,smart_PX_assoc_Snx13,smart_Regulat_G_prot_signal,smart_Phox,pfscan_Phox,pfscan_Phox_assoc,pfscan_Regulat_G_prot_signal	-	no_errors	SNX13	HGNC	ENSG00000071189	767	0	0.00	326	64	16.41	-	-	-
STX10	0	genome.wustl.edu	37	19	13260582	13260582	+	Missense_Mutation	SNP	G	G	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	13260582	13260582	G	T	SNP	STX10	ENST00000587318	human	ensembl	69_37n	-1	putative	missense	c.118	p.Q40K	0.967	pfam_Syntaxin-6_N,superfamily_t-SNARE	pfam_Syntaxin-6_N,pfam_T_SNARE_dom,superfamily_t-SNARE,smart_T_SNARE_dom,pfscan_T_SNARE_dom	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	STX10	HGNC	ENSG00000104915	65	0	0.00	23	24	51.06	-	-	-
SUV420H2	0	genome.wustl.edu	37	19	55853589	55853590	+	Frame_Shift_Ins	INS	-	-	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	55853589	55853590	-	C	INS	SUV420H2	ENST00000255613	human	ensembl	69_37n	+1	known	frame_shift_ins	c.117_118	p.L41fs	0.990:1.000	NULL	pfam_SET_dom,smart_SET_dom,pfscan_SET_dom	-	no_errors	SUV420H2	HGNC	ENSG00000133247	9	0	0.00	4	2	33.33	-	-	-
SYNJ1	0	genome.wustl.edu	37	21	34099183	34099183	+	Silent	SNP	C	C	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	21	34099183	34099183	C	T	SNP	SYNJ1	ENST00000433931	human	ensembl	69_37n	-1	known	silent	c.141	p.R47	0.989	NULL	pfam_Syja_N,pfam_Endo/exonuclease/phosphatase,pfam_DUF1866,superfamily_Endo/exonuclease/phosphatase,smart_IPPc,pfscan_RRM_dom,pfscan_Syja_N	-	no_errors	SYNJ1	HGNC	ENSG00000159082	193	0	0.00	35	10	22.22	-	-	-
TAGLN2	0	genome.wustl.edu	37	1	159889125	159889125	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	159889125	159889125	C	G	SNP	TAGLN2	ENST00000368096	human	ensembl	69_37n	-1	known	missense	c.460	p.G154R	1.000	superfamily_CH-domain,prints_SM22_calponin,pfscan_CH-domain	pfam_CH-domain,pfam_Calponin_repeat,superfamily_CH-domain,smart_CH-domain,prints_SM22_calponin,prints_Transgelin,pfscan_CH-domain,pfscan_Calponin_repeat	-	no_errors	TAGLN2	HGNC	ENSG00000158710	102	0	0.00	88	19	17.76	-	-	-
TCEANC2	0	genome.wustl.edu	37	1	54534542	54534542	+	Silent	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	54534542	54534542	C	A	SNP	TCEANC2	ENST00000371331	human	ensembl	69_37n	+1	known	silent	c.306	p.S102	0.999	pfam_TFIIS_N,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub	pfam_TFIIS_N,superfamily_TFIIS_N,superfamily_TFIIS_cen_dom,smart_TFIIS/CRSP70_N_sub	-	no_errors	TCEANC2	HGNC	ENSG00000116205	106	0	0.00	42	36	46.15	-	-	-
TDRD5	0	genome.wustl.edu	37	1	179632507	179632507	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	179632507	179632507	G	A	SNP	TDRD5	ENST00000444136	human	ensembl	69_37n	+1	known	missense	c.2530	p.D844N	0.032	NULL	pfam_Tudor,smart_Tudor,pfscan_Tudor	-	no_errors	TDRD5	HGNC	ENSG00000162782	238	0	0.00	137	56	29.02	-	-	-
TET3	0	genome.wustl.edu	37	2	74274174	74274174	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	74274174	74274174	C	A	SNP	TET3	ENST00000409262	human	ensembl	69_37n	+1	known	missense	c.725	p.T242N	0.957	NULL	NULL	-	no_errors	TET3	HGNC	ENSG00000187605	71	0	0.00	28	17	37.78	-	-	-
TNRC18	0	genome.wustl.edu	37	7	5352742	5352742	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	7	5352742	5352742	C	A	SNP	TNRC18	ENST00000399537	human	ensembl	69_37n	-1	known	missense	c.7780	p.G2594C	0.540	NULL	pfam_BAH_dom,smart_BAH_dom,pfscan_BAH_dom	-	no_errors	TNRC18	HGNC	ENSG00000182095	13	0	0.00	29	9	23.68	-	-	-
TP53	0	genome.wustl.edu	37	17	7578218	7578218	+	Frame_Shift_Del	DEL	T	T	-			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	17	7578218	7578218	T	-	DEL	TP53	ENST00000269305	human	ensembl	69_37n	-1	known	frame_shift_del	c.631	p.T211fs	0.993	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	402	0	0.00	93	196	63.02	-	-	-
TTN	0	genome.wustl.edu	37	2	179442477	179442477	+	Missense_Mutation	SNP	G	G	C			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	2	179442477	179442477	G	C	SNP	TTN	ENST00000342992	human	ensembl	69_37n	-1	known	missense	c.60972	p.N20324K	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_cat_dom,pfscan_Ig-like	-	no_errors	TTN	HGNC	ENSG00000155657	122	0	0.00	65	24	26.97	-	-	-
TUBA1B	0	genome.wustl.edu	37	12	49523054	49523054	+	Missense_Mutation	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	12	49523054	49523054	C	G	SNP	TUBA1B	ENST00000336023	human	ensembl	69_37n	-1	known	missense	c.346	p.D116H	1.000	pfam_Tubulin_FtsZ_GTPase,superfamily_Tubulin_FtsZ_GTPase,smart_Tubulin_FtsZ_GTPase,prints_Tubulin,prints_Epsilon_tubulin,prints_Beta_tubulin	pfam_Tubulin_FtsZ_GTPase,pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tubulin_FtsZ_GTPase,superfamily_Tub_FtsZ_C,smart_Tubulin_FtsZ_GTPase,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Alpha_tubulin,prints_Tubulin,prints_Epsilon_tubulin,prints_Beta_tubulin,prints_Delta_tubulin	-	no_errors	TUBA1B	HGNC	ENSG00000123416	169	0	0.00	75	18	19.35	-	-	-
TULP4	0	genome.wustl.edu	37	6	158924964	158924964	+	Missense_Mutation	SNP	C	C	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	6	158924964	158924964	C	A	SNP	TULP4	ENST00000367097	human	ensembl	69_37n	+1	known	missense	c.4269	p.S1423R	1.000	NULL	pfam_Tubby_C,pfam_SOCS_C,pfam_WD40_repeat,superfamily_Tubby_C-like,superfamily_WD40_repeat_dom,superfamily_Tumour_necrosis_fac-like,smart_WD40_repeat,smart_SOCS_C,pfscan_SOCS_C,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	TULP4	HGNC	ENSG00000130338	100	0	0.00	8	17	68.00	-	-	-
UNC13A	0	genome.wustl.edu	37	19	17768991	17768991	+	Missense_Mutation	SNP	G	G	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	17768991	17768991	G	A	SNP	UNC13A	ENST00000428389	human	ensembl	69_37n	-1	known	missense	c.911	p.T304M	1.000	NULL	pfam_Munc13_subgr_dom-2,pfam_C2_Ca-dep,pfam_Ca-dep_secretion_activator,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_C2_Ca-dep,smart_Prot_Kinase_C-like_PE/DAG-bd,pfscan_C2_membr_targeting,pfscan_Prot_Kinase_C-like_PE/DAG-bd,prints_C2_dom	-	no_errors	UNC13A	HGNC	ENSG00000130477	99	0	0.00	74	19	20.43	-	-	-
USH2A	0	genome.wustl.edu	37	1	216062079	216062079	+	Missense_Mutation	SNP	T	T	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	216062079	216062079	T	G	SNP	USH2A	ENST00000366943	human	ensembl	69_37n	-1	known	missense	c.7912	p.T2638P	0.997	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_EGF_laminin,pfam_Laminin_G,superfamily_ConA-like_lec_gl,superfamily_Fibronectin_type3,smart_LamG-like,smart_Laminin_N,smart_EGF_laminin,smart_Fibronectin_type3,smart_Laminin_G,pfscan_EGF_laminin,pfscan_Fibronectin_type3,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	USH2A	HGNC	ENSG00000042781	329	0	0.00	156	88	36.07	-	-	-
WDR48	0	genome.wustl.edu	37	3	39118666	39118666	+	Missense_Mutation	SNP	A	A	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	3	39118666	39118666	A	G	SNP	WDR48	ENST00000302313	human	ensembl	69_37n	+1	known	missense	c.934	p.I312V	0.478	superfamily_WD40_repeat_dom	pfam_DUF3337,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,prints_G-protein_beta_WD-40_rep,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDR48	HGNC	ENSG00000114742	119	0	0.00	24	30	55.56	-	-	-
WIPF2	0	genome.wustl.edu	37	17	38412741	38412741	+	Silent	SNP	A	A	T			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	17	38412741	38412741	A	T	SNP	WIPF2	ENST00000323571	human	ensembl	69_37n	+1	known	silent	c.30	p.P10	0.038	NULL	smart_WH2_dom,pfscan_WH2_dom	-	no_errors	WIPF2	HGNC	ENSG00000171475	218	0	0.00	43	69	61.61	-	-	-
ZNF66P	0	genome.wustl.edu	37	19	20989903	20989903	+	Missense_Mutation	SNP	T	T	A			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	19	20989903	20989903	T	A	SNP	ZNF66P	ENST00000344519	human	ensembl	69_37n	+1	novel	missense	c.1497	p.H499Q	0.855	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF66P	HGNC	ENSG00000160229	31	0	0.00	31	7	18.42	-	-	-
ZNF687	0	genome.wustl.edu	37	1	151259889	151259889	+	Silent	SNP	C	C	G			TCGA-AO-A0J6-01A-11W-A050-09	TCGA-AO-A0J6-10A-01W-A055-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	7d21a0c4-03c7-4641-8b4d-7a5877960360	2014e5c3-3ac5-4d79-8942-3ee4e0cbf60d	1	151259889	151259889	C	G	SNP	ZNF687	ENST00000324048	human	ensembl	69_37n	+1	known	silent	c.1122	p.S374	1.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF687	HGNC	ENSG00000143373	74	0	0.00	46	22	32.35	-	-	-
