Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
APOBR	0	genome.wustl.edu	37	16	28507415	28507417	+	In_Frame_Del	DEL	GGA	GGA	-			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	GGA	GGA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	16	28507415	28507417	GGA	-	DEL	APOBR	ENST00000564831	human	ensembl	69_37n	+1	known	in_frame_del	c.1053_1055	p.E353in_frame_del	0.000:0.005:0.010	NULL	NULL	-	no_errors	APOBR	HGNC	ENSG00000184730	17	0	0.00	16	4	18.18	-	-	-
ARHGAP18	0	genome.wustl.edu	37	6	129937374	129937374	+	Missense_Mutation	SNP	G	G	A			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	6	129937374	129937374	G	A	SNP	ARHGAP18	ENST00000275189	human	ensembl	69_37n	-1	known	missense	c.1027	p.P343S	1.000	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	ARHGAP18	HGNC	ENSG00000146376	144	0	0.00	307	74	19.42	-	-	-
CACNA1E	0	genome.wustl.edu	37	1	181726119	181726119	+	Missense_Mutation	SNP	C	C	T			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	1	181726119	181726119	C	T	SNP	CACNA1E	ENST00000367573	human	ensembl	69_37n	+1	known	missense	c.4186	p.R1396C	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,pfscan_EF_HAND_2,prints_VDCCAlpha1,prints_VDCC_R_a1su	-	no_errors	CACNA1E	HGNC	ENSG00000198216	261	0	0.00	510	115	18.40	-	-	-
CIT	0	genome.wustl.edu	37	12	120156088	120156088	+	Missense_Mutation	SNP	G	G	A			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	12	120156088	120156088	G	A	SNP	CIT	ENST00000261833	human	ensembl	69_37n	-1	known	missense	c.4004	p.P1335L	1.000	pirsf_Citron_Rho-interacting_kinase	pfam_Citron,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_HR1_rho-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Pleckstrin_homology,smart_Citron,pirsf_Citron_Rho-interacting_kinase,pfscan_Pleckstrin_homology,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_cat_dom	-	no_errors	CIT	HGNC	ENSG00000122966	80	0	0.00	127	27	17.53	-	-	-
CTAG2	0	genome.wustl.edu	37	X	153881613	153881613	+	Silent	SNP	G	G	A			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	X	153881613	153881613	G	A	SNP	CTAG2	ENST00000369585	human	ensembl	69_37n	-1	known	silent	c.177	p.G59	0.000	NULL	pfam_EKC/KEOPS_Pcc1	-	no_errors	CTAG2	HGNC	ENSG00000126890	11	0	0.00	70	28	28.57	-	-	-
CTGF	0	genome.wustl.edu	37	6	132270681	132270681	+	Missense_Mutation	SNP	C	C	T			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	6	132270681	132270681	C	T	SNP	CTGF	ENST00000367976	human	ensembl	69_37n	-1	known	missense	c.773	p.R258H	1.000	pfam_Cys_knot,pirsf_IGFBP_CNN,pfscan_Cys_knot_C	pfam_Cys_knot,pfam_IGFBP-like,pfam_VWF_C,pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_IGFBP-like,smart_VWF_C,smart_Thrombospondin_1_rpt,smart_Cys_knot_C,pirsf_IGFBP_CNN,pfscan_Cys_knot_C,pfscan_Thrombospondin_1_rpt,pfscan_VWF_C	-	no_errors	CTGF	HGNC	ENSG00000118523	110	0	0.00	187	41	17.98	-	-	-
DDC	0	genome.wustl.edu	37	7	50605566	50605566	+	Missense_Mutation	SNP	C	C	T			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	7	50605566	50605566	C	T	SNP	DDC	ENST00000357936	human	ensembl	69_37n	-1	known	missense	c.427	p.V143M	1.000	pfam_PyrdxlP-dep_de-COase,pfam_ArAA_b-elim_lyase/Thr_aldolase,superfamily_PyrdxlP-dep_Trfase_major_dom,prints_Aromatic_deC	pfam_PyrdxlP-dep_de-COase,pfam_ArAA_b-elim_lyase/Thr_aldolase,superfamily_PyrdxlP-dep_Trfase_major_dom,prints_Aromatic_deC	-	no_errors	DDC	HGNC	ENSG00000132437	223	0	0.00	402	93	18.75	-	-	-
HIPK2	0	genome.wustl.edu	37	7	139257730	139257730	+	Silent	SNP	G	G	C			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	7	139257730	139257730	G	C	SNP	HIPK2	ENST00000406875	human	ensembl	69_37n	-1	known	silent	c.3540	p.T1180	1.000	NULL	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	-	no_errors	HIPK2	HGNC	ENSG00000064393	152	0	0.00	199	58	22.57	-	-	-
NARS2	0	genome.wustl.edu	37	11	78204212	78204212	+	Missense_Mutation	SNP	G	G	C			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	11	78204212	78204212	G	C	SNP	NARS2	ENST00000281038	human	ensembl	69_37n	-1	known	missense	c.719	p.P240R	1.000	pfam_aa-tRNA-synt_II,pfscan_aa-tRNA-synth_II,prints_Asp/Asn-tRNA-synth_IIb,tigrfam_Asn-tRNA-synth_IIb	pfam_aa-tRNA-synt_II,pfam_NA-bd_OB_tRNA-helicase,superfamily_NA-bd_OB-fold-like,pfscan_aa-tRNA-synth_II,prints_Asp/Asn-tRNA-synth_IIb,tigrfam_Asn-tRNA-synth_IIb	-	no_errors	NARS2	HGNC	ENSG00000137513	43	0	0.00	189	31	13.96	-	-	-
OR4N4	0	genome.wustl.edu	37	15	22382595	22382595	+	Silent	SNP	A	A	G			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	15	22382595	22382595	A	G	SNP	OR4N4	ENST00000328795	human	ensembl	69_37n	+1	known	silent	c.123	p.G41	0.998	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_7TM_GPCR_Rhodpsn	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn	-	no_errors	OR4N4	HGNC	ENSG00000183706	478	0	0.00	1096	134	10.89	-	-	-
PIK3CA	0	genome.wustl.edu	37	3	178936095	178936095	+	Missense_Mutation	SNP	A	A	G			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	3	178936095	178936095	A	G	SNP	PIK3CA	ENST00000263967	human	ensembl	69_37n	+1	known	missense	c.1637	p.Q546R	1.000	pfam_PInositide-3_kin_accessory_dom,superfamily_ARM-type_fold,smart_PInositide-3_kin_accessory_dom	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CA	HGNC	ENSG00000121879	63	0	0.00	140	42	23.08	-	-	-
RAD21	0	genome.wustl.edu	37	8	117862955	117862955	+	Missense_Mutation	SNP	C	C	G			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	8	117862955	117862955	C	G	SNP	RAD21	ENST00000297338	human	ensembl	69_37n	-1	known	missense	c.1522	p.E508Q	1.000	NULL	pfam_Rad21_Rec8_N,pfam_Rad21/Rec8_C_eu,pfam_ScpA	-	no_errors	RAD21	HGNC	ENSG00000164754	228	0	0.00	487	126	20.55	-	-	-
TTN	0	genome.wustl.edu	37	2	179467306	179467306	+	Missense_Mutation	SNP	G	G	T			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	2	179467306	179467306	G	T	SNP	TTN	ENST00000342992	human	ensembl	69_37n	-1	known	missense	c.47119	p.P15707T	0.922	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_cat_dom,pfscan_Ig-like	-	no_errors	TTN	HGNC	ENSG00000155657	78	0	0.00	180	55	23.40	-	-	-
ZNF45	0	genome.wustl.edu	37	19	44418767	44418767	+	Missense_Mutation	SNP	T	T	C			TCGA-A2-A0EW-01A-21D-A10Y-09	TCGA-A2-A0EW-10A-01D-A110-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	a045a04e-4f7b-4f9a-a733-47ad24475496	7ada2974-e227-405b-82c2-53909e722858	19	44418767	44418767	T	C	SNP	ZNF45	ENST00000269973	human	ensembl	69_37n	-1	known	missense	c.821	p.K274R	1.000	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF45	HGNC	ENSG00000124459	127	0	0.00	222	56	20.14	-	-	-
