Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
ASXL1	0	genome.wustl.edu	37	20	31023102	31023102	+	Missense_Mutation	SNP	G	G	C			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	20	31023102	31023102	G	C	SNP	ASXL1	ENST00000375687	human	ensembl	69_37n	+1	known	missense	c.2587	p.D863H	0.035	NULL	NULL	-	no_errors	ASXL1	HGNC	ENSG00000171456	178	0	0.00	486	70	12.57	-	-	-
ASXL1	0	genome.wustl.edu	37	20	31023531	31023531	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	20	31023531	31023531	G	A	SNP	ASXL1	ENST00000375687	human	ensembl	69_37n	+1	known	missense	c.3016	p.E1006K	1.000	NULL	NULL	-	no_errors	ASXL1	HGNC	ENSG00000171456	92	0	0.00	221	37	14.34	-	-	-
ASXL1	0	genome.wustl.edu	37	20	31024108	31024108	+	Missense_Mutation	SNP	G	G	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	20	31024108	31024108	G	T	SNP	ASXL1	ENST00000375687	human	ensembl	69_37n	+1	known	missense	c.3593	p.G1198V	0.056	NULL	NULL	-	no_errors	ASXL1	HGNC	ENSG00000171456	92	0	0.00	145	20	12.12	-	-	-
CC2D1B	0	genome.wustl.edu	37	1	52824769	52824769	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	1	52824769	52824769	C	T	SNP	CC2D1B	ENST00000371586	human	ensembl	69_37n	-1	known	missense	c.1187	p.R396H	0.248	smart_DM14	pfam_C2_Ca-dep,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_DM14,smart_C2_Ca-dep	-	no_errors	CC2D1B	HGNC	ENSG00000154222	28	0	0.00	50	8	13.79	-	-	-
CYP26B1	0	genome.wustl.edu	37	2	72371201	72371201	+	Nonsense_Mutation	SNP	C	C	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	2	72371201	72371201	C	A	SNP	CYP26B1	ENST00000001146	human	ensembl	69_37n	-1	known	nonsense	c.346	p.E116*	1.000	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_B,prints_Cyt_P450	-	no_errors	CYP26B1	HGNC	ENSG00000003137	16	0	0.00	7	7	50.00	-	-	-
ECM1	0	genome.wustl.edu	37	1	150485271	150485271	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	1	150485271	150485271	T	C	SNP	ECM1	ENST00000369049	human	ensembl	69_37n	+1	known	missense	c.1456	p.C486R	1.000	pfam_ECM1	pfam_ECM1,superfamily_Serum_albumin-like	-	no_errors	ECM1	HGNC	ENSG00000143369	160	0	0.00	269	81	23.14	-	-	-
GYS1	0	genome.wustl.edu	37	19	49489210	49489210	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	19	49489210	49489210	C	T	SNP	GYS1	ENST00000323798	human	ensembl	69_37n	-1	known	missense	c.575	p.R192H	0.994	pfam_Glycogen_synth,pfam_Starch_synth_cat_dom	pfam_Glycogen_synth,pfam_Glyco_trans_1,pfam_Starch_synth_cat_dom	-	no_errors	GYS1	HGNC	ENSG00000104812	30	0	0.00	28	15	34.88	-	-	-
IQGAP1	0	genome.wustl.edu	37	15	91019954	91019954	+	Missense_Mutation	SNP	G	G	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	15	91019954	91019954	G	T	SNP	IQGAP1	ENST00000268182	human	ensembl	69_37n	+1	known	missense	c.2844	p.M948I	1.000	NULL	pfam_RasGAP,pfam_RasGAP_C,pfam_IQ_motif_EF-hand-BS,pfam_CH-domain,pfam_WW_Rsp5_WWP,superfamily_Rho_GTPase_activation_prot,superfamily_CH-domain,smart_CH-domain,smart_WW_Rsp5_WWP,smart_IQ_motif_EF-hand-BS,smart_RasGAP,pfscan_CH-domain,pfscan_IQ_motif_EF-hand-BS,pfscan_WW_Rsp5_WWP,pfscan_RasGAP	-	no_errors	IQGAP1	HGNC	ENSG00000140575	282	0	0.00	93	139	59.91	-	-	-
KANK4	0	genome.wustl.edu	37	1	62740107	62740107	+	Silent	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	1	62740107	62740107	C	T	SNP	KANK4	ENST00000371153	human	ensembl	69_37n	-1	known	silent	c.669	p.R223	0.000	NULL	pfam_KN_motif,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	KANK4	HGNC	ENSG00000132854	37	0	0.00	45	13	22.41	-	-	-
KANSL3	0	genome.wustl.edu	37	2	97278595	97278595	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	2	97278595	97278595	C	T	SNP	KANSL3	ENST00000431828	human	ensembl	69_37n	-1	known	missense	c.872	p.R291H	1.000	NULL	NULL	-	no_errors	KANSL3	HGNC	ENSG00000114982	19	0	0.00	21	8	27.59	-	-	-
KIAA0895	0	genome.wustl.edu	37	7	36366445	36366445	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	7	36366445	36366445	C	T	SNP	KIAA0895	ENST00000297063	human	ensembl	69_37n	-1	known	missense	c.1487	p.G496D	0.003	pfam_DUF1704	pfam_DUF1704	-	no_errors	KIAA0895	HGNC	ENSG00000164542	151	0	0.00	153	51	25.00	-	-	-
LPA	0	genome.wustl.edu	37	6	161022000	161022000	+	Missense_Mutation	SNP	C	C	G			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	6	161022000	161022000	C	G	SNP	LPA	ENST00000316300	human	ensembl	69_37n	-1	known	missense	c.3076	p.V1026L	0.000	superfamily_Kringle-like	pfam_Kringle,pfam_Peptidase_S1_S6,pfam_Peptidase_S1A_nudel,superfamily_Pept_cys/ser_Trypsin-like,superfamily_Kringle-like,smart_Kringle,smart_Peptidase_S1_S6,prints_Peptidase_S1A,pfscan_Kringle,pfscan_Peptidase_S1_S6	-	no_errors	LPA	HGNC	ENSG00000198670	224	0	0.00	171	69	28.75	-	-	-
LRIG2	0	genome.wustl.edu	37	1	113616247	113616248	+	Frame_Shift_Ins	INS	-	-	C			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	1	113616247	113616248	-	C	INS	LRIG2	ENST00000361127	human	ensembl	69_37n	+1	known	frame_shift_ins	c.219_220	p.D75fs	1.000:1.000	NULL	pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Immunoglobulin,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like	-	no_errors	LRIG2	HGNC	ENSG00000198799	21	0	0.00	29	4	12.12	-	-	-
MLL2	0	genome.wustl.edu	37	12	49436351	49436351	+	Missense_Mutation	SNP	C	C	G			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	12	49436351	49436351	C	G	SNP	MLL2	ENST00000301067	human	ensembl	69_37n	-1	known	missense	c.5860	p.D1954H	1.000	NULL	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_superfamily,smart_Znf_PHD,smart_Znf_RING,smart_HMG_superfamily,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	MLL2	HGNC	ENSG00000167548	57	0	0.00	80	26	24.53	-	-	-
MYH14	0	genome.wustl.edu	37	19	50750310	50750310	+	Silent	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	19	50750310	50750310	C	T	SNP	MYH14	ENST00000262269	human	ensembl	69_37n	+1	known	silent	c.1260	p.S420	1.000	pfam_Myosin_head_motor_dom,smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_Myosin_tail,pfam_Myosin_N,superfamily_Prefoldin,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH14	HGNC	ENSG00000105357	13	0	0.00	11	12	52.17	-	-	-
MYO5B	0	genome.wustl.edu	37	18	47463624	47463624	+	Silent	SNP	A	A	G			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	18	47463624	47463624	A	G	SNP	MYO5B	ENST00000285039	human	ensembl	69_37n	-1	known	silent	c.1896	p.V632	1.000	pfam_Myosin_head_motor_dom,smart_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_Dil_domain,pfam_IQ_motif_EF-hand-BS,superfamily_Prefoldin,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_Dilute,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYO5B	HGNC	ENSG00000167306	191	0	0.00	231	59	20.27	-	-	-
NBPF10	0	genome.wustl.edu	37	1	145319647	145319647	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	1	145319647	145319647	T	C	SNP	NBPF10	ENST00000342960	human	ensembl	69_37n	+1	known	missense	c.2834	p.V945A	0.000	pfam_NBPF_dom	pfam_NBPF_dom	-	no_errors	NBPF10	HGNC	ENSG00000163386	37	0	0.00	45	5	10.00	-	-	-
NEDD4L	0	genome.wustl.edu	37	18	56010162	56010162	+	Missense_Mutation	SNP	C	C	G			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	18	56010162	56010162	C	G	SNP	NEDD4L	ENST00000400345	human	ensembl	69_37n	+1	known	missense	c.1402	p.R468G	0.997	NULL	pfam_HECT,pfam_WW_Rsp5_WWP,pfam_C2_Ca-dep,superfamily_HECT,superfamily_C2_Ca/lipid-bd_dom_CaLB,superfamily_WW_Rsp5_WWP,smart_C2_Ca-dep,smart_WW_Rsp5_WWP,smart_HECT,pfscan_HECT,pfscan_C2_membr_targeting,pfscan_WW_Rsp5_WWP,prints_C2_dom	-	no_errors	NEDD4L	HGNC	ENSG00000049759	127	0	0.00	123	28	18.54	-	-	-
NOTCH3	0	genome.wustl.edu	37	19	15271757	15271758	+	Frame_Shift_Del	DEL	TG	TG	-			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	TG	TG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	19	15271757	15271758	TG	-	DEL	NOTCH3	ENST00000263388	human	ensembl	69_37n	-1	known	frame_shift_del	c.6682_6681	p.H2227fs	0.005:0.002	pfam_DUF3454_notch,pirsf_Notch	pfam_EGF-like_dom,pfam_EGF-like_Ca-bd,pfam_Ankyrin_rpt,pfam_Notch_dom,pfam_Notch_NODP_dom,pfam_Notch_NOD_dom,pfam_EGF_extracell,pfam_DUF3454_notch,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EGF-like,smart_EGF-like_Ca-bd,smart_Notch_dom,smart_Ankyrin_rpt,pirsf_Notch,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom,prints_Notch_3,prints_Notch_dom	-	no_errors	NOTCH3	HGNC	ENSG00000074181	14	0	0.00	11	4	26.67	-	-	-
NOTCH4	0	genome.wustl.edu	37	6	32180644	32180644	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	6	32180644	32180644	G	A	SNP	NOTCH4	ENST00000375023	human	ensembl	69_37n	-1	known	missense	c.2483	p.P828L	0.936	pfam_EGF-like_dom,smart_EGF-like,smart_EGF-like_Ca-bd,pirsf_Notch,pfscan_EG-like_dom	pfam_EGF-like_dom,pfam_Ankyrin_rpt,pfam_EGF-like_Ca-bd,pfam_Notch_dom,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EGF-like,smart_EGF-like_Ca-bd,smart_Notch_dom,smart_Ankyrin_rpt,pirsf_Notch,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom,prints_Notch_4,prints_Notch_dom	-	no_errors	NOTCH4	HGNC	ENSG00000204301	22	0	0.00	22	19	46.34	-	-	-
PSMA7	0	genome.wustl.edu	37	20	60714888	60714888	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	20	60714888	60714888	C	T	SNP	PSMA7	ENST00000442551	human	ensembl	69_37n	-1	known	missense	c.74	p.R25K	1.000	pfam_Proteasome_sua/b	pfam_Proteasome_sua/b	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	PSMA7	HGNC	ENSG00000101182	13	0	0.00	20	10	33.33	-	-	-
RABGAP1	0	genome.wustl.edu	37	9	125863868	125863868	+	Silent	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	9	125863868	125863868	G	A	SNP	RABGAP1	ENST00000373647	human	ensembl	69_37n	+1	known	silent	c.2913	p.R971	1.000	NULL	pfam_Rab-GTPase-TBC_dom,pfam_Kinesin-like,pfam_PTyr_interaction_dom,superfamily_Rab-GTPase-TBC_dom,smart_PTyr_interaction_dom,smart_Rab-GTPase-TBC_dom,pfscan_PTyr_interaction_dom,pfscan_Rab-GTPase-TBC_dom	-	no_errors	RABGAP1	HGNC	ENSG00000011454	78	0	0.00	67	14	17.28	-	-	-
RBM15B	0	genome.wustl.edu	37	3	51431352	51431353	+	Frame_Shift_Ins	INS	-	-	G			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	3	51431352	51431353	-	G	INS	RBM15B	ENST00000323686	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.2522_2523	p.S844fs	1.000:1.000	pfam_SPOC_C,superfamily_SPOC-like,pfscan_SPOC_met	pfam_RRM_dom,pfam_SPOC_C,superfamily_SPOC-like,smart_RRM_dom,pfscan_SPOC_met,pfscan_RRM_dom	-	no_errors	RBM15B	HGNC	ENSG00000179837	40	0	0.00	26	3	10.34	-	-	-
REXO2	0	genome.wustl.edu	37	11	114320615	114320615	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	11	114320615	114320615	G	A	SNP	REXO2	ENST00000265881	human	ensembl	69_37n	+1	known	missense	c.632	p.R211Q	1.000	superfamily_RNaseH-like_dom,smart_Exonuclease	pfam_Exonuclease_RNaseT/DNA_pol3,superfamily_RNaseH-like_dom,smart_Exonuclease	-	no_errors	REXO2	HGNC	ENSG00000076043	207	0	0.00	197	86	30.39	-	-	-
RNF213	0	genome.wustl.edu	37	17	78321232	78321232	+	Missense_Mutation	SNP	G	G	C			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	17	78321232	78321232	G	C	SNP	RNF213	ENST00000582970	human	ensembl	69_37n	+1	known	missense	c.9097	p.E3033Q	0.000	NULL	smart_AAA+_ATPase,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF213	HGNC	ENSG00000173821	43	0	0.00	26	32	55.17	-	-	-
RYR1	0	genome.wustl.edu	37	19	39018962	39018962	+	Missense_Mutation	SNP	A	A	G			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	19	39018962	39018962	A	G	SNP	RYR1	ENST00000359596	human	ensembl	69_37n	+1	known	missense	c.10841	p.K3614R	1.000	NULL	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR,superfamily_ConA-like_lec_gl,superfamily_MG_RAP_rcpt_1,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_MIR_motif	-	no_errors	RYR1	HGNC	ENSG00000196218	46	0	0.00	37	23	38.33	-	-	-
SCAMP2	0	genome.wustl.edu	37	15	75146427	75146427	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	15	75146427	75146427	G	A	SNP	SCAMP2	ENST00000268099	human	ensembl	69_37n	-1	known	missense	c.160	p.L54F	0.334	NULL	pfam_SCAMP	-	no_errors	SCAMP2	HGNC	ENSG00000140497	14	0	0.00	13	12	48.00	-	-	-
SGCD	0	genome.wustl.edu	37	5	156074477	156074477	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	5	156074477	156074477	C	T	SNP	SGCD	ENST00000337851	human	ensembl	69_37n	+1	known	missense	c.506	p.A169V	0.999	pfam_Sarcoglycan	pfam_Sarcoglycan	-	no_errors	SGCD	HGNC	ENSG00000170624	14	0	0.00	15	7	31.82	-	-	-
SIPA1	0	genome.wustl.edu	37	11	65413699	65413701	+	In_Frame_Del	DEL	GGA	GGA	-			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	GGA	GGA					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	11	65413699	65413701	GGA	-	DEL	SIPA1	ENST00000394224	human	ensembl	69_37n	+1	known	in_frame_del	c.1271_1273	p.RK424in_frame_delQ	1.000:1.000:1.000	pfam_Rap_GAP,pfscan_Rap_GAP	pfam_Rap_GAP,pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ,pfscan_Rap_GAP	-	no_errors	SIPA1	HGNC	ENSG00000213445	68	0	0.00	67	30	29.70	-	-	-
SLC22A14	0	genome.wustl.edu	37	3	38348770	38348771	+	Frame_Shift_Del	DEL	CG	CG	-			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	CG	CG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	3	38348770	38348771	CG	-	DEL	SLC22A14	ENST00000273173	human	ensembl	69_37n	+1	known	frame_shift_del	c.542_543	p.T181fs	0.000:0.000	superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC22A14	HGNC	ENSG00000144671	54	0	0.00	48	7	12.73	-	-	-
TAS2R43	0	genome.wustl.edu	37	12	11244488	11244488	+	Missense_Mutation	SNP	G	G	C			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	12	11244488	11244488	G	C	SNP	TAS2R43	ENST00000531678	human	ensembl	69_37n	-1	known	missense	c.341	p.S114C	0.139	pfam_TAS2_rcpt	pfam_TAS2_rcpt	-	no_errors	TAS2R43	HGNC	ENSG00000255374	337	0	0.00	601	216	26.37	-	-	-
TMPRSS15	0	genome.wustl.edu	37	21	19666646	19666646	+	Silent	SNP	G	G	C			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	21	19666646	19666646	G	C	SNP	TMPRSS15	ENST00000284885	human	ensembl	69_37n	-1	known	silent	c.2427	p.L809	0.102	pfam_Peptidase_S1_S6,pfam_Peptidase_S1A_nudel,superfamily_Pept_cys/ser_Trypsin-like,smart_Peptidase_S1_S6,pfscan_Peptidase_S1_S6	pfam_Peptidase_S1_S6,pfam_CUB,pfam_MAM_dom,pfam_SEA,pfam_LDrepeatLR_classA_rpt,pfam_Peptidase_S1A_nudel,pfam_Srcr_rcpt,superfamily_Pept_cys/ser_Trypsin-like,superfamily_ConA-like_lec_gl,superfamily_CUB,superfamily_LDrepeatLR_classA_rpt,superfamily_Srcr_rcpt-rel,smart_SEA,smart_LDrepeatLR_classA_rpt,smart_CUB,smart_MAM_dom,smart_Srcr_rcpt-rel,smart_Peptidase_S1_S6,pfscan_CUB,pfscan_LDrepeatLR_classA_rpt,pfscan_MAM_dom,pfscan_SEA,pfscan_Srcr_rcpt,pfscan_Peptidase_S1_S6,prints_Peptidase_S1A	-	no_errors	TMPRSS15	HGNC	ENSG00000154646	80	0	0.00	68	36	34.62	-	-	-
TP53	0	genome.wustl.edu	37	17	7577106	7577106	+	Missense_Mutation	SNP	G	G	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	17	7577106	7577106	G	T	SNP	TP53	ENST00000269305	human	ensembl	69_37n	-1	known	missense	c.832	p.P278T	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	55	0	0.00	40	39	49.37	-	-	-
USP12	0	genome.wustl.edu	37	13	27679970	27679970	+	Missense_Mutation	SNP	G	G	T			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	13	27679970	27679970	G	T	SNP	USP12	ENST00000282344	human	ensembl	69_37n	-1	known	missense	c.241	p.L81I	0.998	pfam_Peptidase_C19,pfscan_Peptidase_C19	pfam_Peptidase_C19,pfscan_Peptidase_C19	-	no_errors	USP12	HGNC	ENSG00000152484	138	0	0.00	233	57	19.66	-	-	-
USP36	0	genome.wustl.edu	37	17	76799860	76799861	+	Frame_Shift_Ins	INS	-	-	G			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	17	76799860	76799861	-	G	INS	USP36	ENST00000312010	human	ensembl	69_37n	-1	known	frame_shift_ins	c.2417_2416	p.Q806fs	0.000:0.000	NULL	pfam_Peptidase_C19,pfscan_Peptidase_C19	-	no_errors	USP36	HGNC	ENSG00000055483	14	0	0.00	29	5	14.71	-	-	-
WWC3	0	genome.wustl.edu	37	X	10102551	10102551	+	Frame_Shift_Del	DEL	C	C	-			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	X	10102551	10102551	C	-	DEL	WWC3	ENST00000380861	human	ensembl	69_37n	+1	known	frame_shift_del	c.2678	p.R894fs	0.075	NULL	superfamily_C2_Ca/lipid-bd_dom_CaLB	-	no_errors	WWC3	HGNC	ENSG00000047644	176	0	0.00	109	71	36.41	-	-	-
XKR4	0	genome.wustl.edu	37	8	56435863	56435863	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	8	56435863	56435863	G	A	SNP	XKR4	ENST00000327381	human	ensembl	69_37n	+1	known	missense	c.1030	p.V344M	0.999	pfam_Transport_prot_XK	pfam_Transport_prot_XK	-	no_errors	XKR4	HGNC	ENSG00000206579	86	0	0.00	119	45	27.44	-	-	-
ZFPM2	0	genome.wustl.edu	37	8	106814408	106814408	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	8	106814408	106814408	G	A	SNP	ZFPM2	ENST00000407775	human	ensembl	69_37n	+1	known	missense	c.2098	p.E700K	1.000	smart_Znf_C2H2-like	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZFPM2	HGNC	ENSG00000169946	88	0	0.00	91	33	26.61	-	-	-
ZNF655	0	genome.wustl.edu	37	7	99158245	99158245	+	Silent	SNP	G	G	A			TCGA-BH-A0B9-01A-11W-A071-09	TCGA-BH-A0B9-10A-01W-A071-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	c57595bb-7953-4611-b0d1-3c2c40feb3b9	02613b8d-b01c-401a-a0be-71f258dea92a	7	99158245	99158245	G	A	SNP	ZNF655	ENST00000424881	human	ensembl	69_37n	+1	known	silent	c.63	p.E21	0.315	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF655	HGNC	ENSG00000197343	52	0	0.00	67	33	33.00	-	-	-
