Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
GPR124	25960	broad.mit.edu	37	8	37697651	37697651	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr8:37697651C>G	ENST00000315215.7	+	14	2236	c.1873C>G	c.(1873-1875)Ctg>Gtg	p.L625V	GPR124_ENST00000412232.2_Missense_Mutation_p.L842V			Q96PE1	GP124_HUMAN	G protein-coupled receptor 124	842					central nervous system development|endothelial cell migration|neuropeptide signaling pathway|regulation of angiogenesis|regulation of chemotaxis|sprouting angiogenesis	integral to membrane|plasma membrane	G-protein coupled receptor activity			central_nervous_system(1)|endometrium(5)|kidney(3)|large_intestine(4)|lung(16)|ovary(4)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	37			BRCA - Breast invasive adenocarcinoma(5;2.75e-24)|LUSC - Lung squamous cell carcinoma(8;3.5e-10)			GGGCATCACCCTGCACTACTC	0.652000													6	44					0	0	1	0	0
GLG1	2734	broad.mit.edu	37	16	74502950	74502950	+	Missense_Mutation	SNP	A	A	C			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr16:74502950A>C	ENST00000422840.2	-	17	2329	c.2330T>G	c.(2329-2331)gTg>gGg	p.V777G	GLG1_ENST00000205061.5_Missense_Mutation_p.V777G|GLG1_ENST00000447066.2_Missense_Mutation_p.V766G	NM_001145667.1	NP_001139139.1	Q92896	GSLG1_HUMAN	golgi glycoprotein 1	777						Golgi membrane|integral to membrane	receptor binding			breast(2)|cervix(2)|endometrium(6)|kidney(8)|large_intestine(6)|lung(28)|ovary(3)|prostate(1)|skin(1)	57						CAGGCAGATCACCACGTCCAC	0.622000													15	27					0	0	1	0	0
PCDHB7	0	broad.mit.edu	37	5	140553994	140553994	+	Silent	SNP	G	G	T			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr5:140553994G>T	ENST00000231137.3	+	1	1752	c.1578G>T	c.(1576-1578)gcG>gcT	p.A526A		NM_018940.2	NP_061763.1	Q9Y5E2	PCDB7_HUMAN		526	Cadherin 5.				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding	p.A526A(1)		NS(2)|breast(2)|central_nervous_system(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(20)|lung(54)|ovary(5)|prostate(7)|skin(7)|upper_aerodigestive_tract(4)|urinary_tract(1)	119			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			CCCTGCAGGCGTTCGAGTTCC	0.706000													5	102					3.59834e-05	3.7619e-05	1	1	0
BMP2K	55589	broad.mit.edu	37	4	79792085	79792085	+	Missense_Mutation	SNP	G	G	C	rs71828885		TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr4:79792085G>C	ENST00000335016.5	+	11	1546	c.1380G>C	c.(1378-1380)caG>caC	p.Q460H	BMP2K_ENST00000502871.1_Missense_Mutation_p.Q460H	NM_198892.1	NP_942595.1	Q9NSY1	BMP2K_HUMAN	BMP2 inducible kinase	460	Gln/His-rich.					nucleus	ATP binding|protein serine/threonine kinase activity	p.Q460H(3)		NS(1)|breast(1)|endometrium(4)|large_intestine(2)|lung(3)|prostate(1)|urinary_tract(1)	13						ATCCTCACcagcagcagcagc	0.577000													3	40					0	0	1	0	0
BRCA2	675	broad.mit.edu	37	13	32968858	32968858	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr13:32968858T>C	ENST00000544455.1	+	25	9516	c.9289T>C	c.(9289-9291)Tgt>Cgt	p.C3097R	BRCA2_ENST00000380152.3_Missense_Mutation_p.C3097R	NM_000059.3	NP_000050.2	P51587	BRCA2_HUMAN	breast cancer 2, early onset	3097					cell cycle cytokinesis|centrosome duplication|double-strand break repair via homologous recombination|negative regulation of mammary gland epithelial cell proliferation|nucleotide-excision repair|positive regulation of transcription, DNA-dependent|regulation of S phase of mitotic cell cycle	BRCA2-MAGE-D1 complex|centrosome|nucleoplasm|stored secretory granule	gamma-tubulin binding|H3 histone acetyltransferase activity|H4 histone acetyltransferase activity|protease binding|single-stranded DNA binding			NS(3)|breast(13)|central_nervous_system(5)|cervix(2)|endometrium(24)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(32)|liver(1)|lung(41)|oesophagus(5)|ovary(22)|pancreas(4)|prostate(3)|salivary_gland(1)|skin(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	183		Lung SC(185;0.0262)		all cancers(112;7.13e-07)|Epithelial(112;1.59e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.000732)|BRCA - Breast invasive adenocarcinoma(63;0.0291)|GBM - Glioblastoma multiforme(144;0.0704)		GTCAGACGAATGTTACAATTT	0.353000			"""D, Mis, N, F, S"""		"""breast, ovarian, pancreatic"""	"""breast, ovarian, pancreatic, leukemia  (FANCB, FANCD1)"""		Homologous recombination	Pancreatic Cancer, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Prostate Cancer;Hereditary Breast-Ovarian Cancer, BRCA2 type;Fanconi Anemia type D1, bi-allelic BRCA2 mutations;Fanconi Anemia	TCGA Ovarian(8;0.087)			39	76					0	0	1	0	0
RAPH1	65059	broad.mit.edu	37	2	204354775	204354775	+	Silent	SNP	G	G	A			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr2:204354775G>A	ENST00000319170.5	-	4	563	c.264C>T	c.(262-264)gcC>gcT	p.A88A	RAPH1_ENST00000308091.4_Silent_p.A88A|RAPH1_ENST00000439222.1_Silent_p.A88A|RAPH1_ENST00000419464.1_Silent_p.A88A|RAPH1_ENST00000374488.2_Silent_p.A88A|RAPH1_ENST00000374493.3_Silent_p.A88A|RAPH1_ENST00000423104.1_Silent_p.A88A|RAPH1_ENST00000457812.1_Silent_p.A88A|RAPH1_ENST00000418114.1_Silent_p.A88A|RAPH1_ENST00000374489.2_Silent_p.A88A|RAPH1_ENST00000453034.1_Silent_p.A88A	NM_213589.1	NP_998754.1	Q70E73	RAPH1_HUMAN	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	88					cell-matrix adhesion|signal transduction	cytoplasm|cytoskeleton|filopodium|lamellipodium|nucleus|plasma membrane				breast(5)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|lung(7)|ovary(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	32						CAGCCATCAAGGCATCCAGAT	0.393000													4	111					0	0	1	0	0
ZNF77	58492	broad.mit.edu	37	19	2936578	2936578	+	Missense_Mutation	SNP	T	T	G			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr19:2936578T>G	ENST00000314531.4	-	3	347	c.255A>C	c.(253-255)gaA>gaC	p.E85D		NM_021217.2	NP_067040.1	Q15935	ZNF77_HUMAN	zinc finger protein 77	85	KRAB.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleolus	DNA binding|zinc ion binding			breast(2)|endometrium(3)|kidney(3)|large_intestine(3)|lung(5)|ovary(1)	17				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|GBM - Glioblastoma multiforme(1328;2.11e-07)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|Lung(535;0.174)|STAD - Stomach adenocarcinoma(1328;0.18)		ATCTCCAATTTTCTCCAAAAA	0.468000													25	46					0	0	1	0	0
IHH	3549	broad.mit.edu	37	2	219924911	219924911	+	Missense_Mutation	SNP	G	G	C			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr2:219924911G>C	ENST00000295731.5	-	1	278	c.279C>G	c.(277-279)gaC>gaG	p.D93E		NM_002181.3	NP_002172.2	Q14623	IHH_HUMAN	indian hedgehog	93					cell-cell signaling|intein-mediated protein splicing|proteolysis	extracellular space|plasma membrane	cholesterol binding|patched binding|peptidase activity			breast(1)|endometrium(2)|large_intestine(1)|lung(8)|skin(1)|upper_aerodigestive_tract(1)	14		Renal(207;0.0915)		Epithelial(149;1.13e-06)|all cancers(144;0.000188)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		TGTTCTCCTCGTCCTTGAAGA	0.657000													22	72					0	0	1	0	0
NUDCD2	134492	broad.mit.edu	37	5	162886940	162886940	+	Silent	SNP	G	G	T	rs141206788		TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr5:162886940G>T	ENST00000302764.4	-	1	206	c.117C>A	c.(115-117)cgC>cgA	p.R39R	NUDCD2_ENST00000517501.1_Silent_p.R39R	NM_145266.4	NP_660309.1	Q8WVJ2	NUDC2_HUMAN	NudC domain containing 2	39	CS.					intracellular				large_intestine(1)|prostate(1)	2	Renal(175;0.000281)	Medulloblastoma(196;0.0207)|all_neural(177;0.0966)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.0981)|OV - Ovarian serous cystadenocarcinoma(192;0.183)|Epithelial(171;0.247)		TATCCTGGGCGCGCGTGCCTG	0.672000													57	82					1.74971e-23	1.91635e-23	1	1	0
IFITM3	10410	broad.mit.edu	37	11	320649	320649	+	Silent	SNP	G	G	A	rs11553885	by1000genomes	TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr11:320649G>A	ENST00000399808.4	-	1	401	c.165C>T	c.(163-165)ccC>ccT	p.P55P	RP11-326C3.11_ENST00000602429.1_RNA|IFITM3_ENST00000602735.1_Silent_p.P34P|RP11-326C3.11_ENST00000602756.1_RNA|IFITM3_ENST00000526811.1_Silent_p.P34P	NM_021034.2	NP_066362.2	Q01628	IFM3_HUMAN	interferon induced transmembrane protein 3	55					response to virus|type I interferon-mediated signaling pathway	integral to membrane|plasma membrane		p.P55P(5)		central_nervous_system(7)|endometrium(7)|kidney(2)|large_intestine(1)|lung(1)	18		all_cancers(49;2e-09)|all_epithelial(84;3.36e-06)|Breast(177;0.000162)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.0538)|all_lung(207;0.0713)		all cancers(45;8.85e-28)|Epithelial(43;5.52e-27)|OV - Ovarian serous cystadenocarcinoma(40;1.11e-20)|BRCA - Breast invasive adenocarcinoma(625;3.56e-05)|Lung(200;0.0327)|LUSC - Lung squamous cell carcinoma(625;0.122)		CGACATGGTCGGGCACGGAGG	0.637000													9	108					0	0	1	0	0
SCYL2	55681	broad.mit.edu	37	12	100722992	100722992	+	Silent	SNP	T	T	C			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr12:100722992T>C	ENST00000360820.2	+	13	2093	c.1656T>C	c.(1654-1656)tgT>tgC	p.C552C		NM_017988.4	NP_060458.3	Q6P3W7	SCYL2_HUMAN	SCY1-like 2 (S. cerevisiae)	552					endosome to lysosome transport|negative regulation of canonical Wnt receptor signaling pathway|positive regulation of clathrin-mediated endocytosis|positive regulation of receptor internalization	clathrin-coated vesicle|endosome membrane|Golgi apparatus|perinuclear region of cytoplasm	ATP binding|protein kinase activity|receptor binding			central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(12)|large_intestine(4)|lung(15)|ovary(2)|skin(1)	41						TTTACAAATGTACTTTTACTC	0.313000													4	58					0	0	1	0	0
NUDCD2	134492	broad.mit.edu	37	5	162886941	162886941	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr5:162886941C>T	ENST00000302764.4	-	1	205	c.116G>A	c.(115-117)cGc>cAc	p.R39H	NUDCD2_ENST00000517501.1_Missense_Mutation_p.R39H	NM_145266.4	NP_660309.1	Q8WVJ2	NUDC2_HUMAN	NudC domain containing 2	39	CS.					intracellular				large_intestine(1)|prostate(1)	2	Renal(175;0.000281)	Medulloblastoma(196;0.0207)|all_neural(177;0.0966)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.0981)|OV - Ovarian serous cystadenocarcinoma(192;0.183)|Epithelial(171;0.247)		ATCCTGGGCGCGCGTGCCTGG	0.672000													56	81					0	0	1	0	0
MLLT6	4302	broad.mit.edu	37	17	36873756	36873756	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr17:36873756C>T	ENST00000325718.7	+	11	1814	c.1723C>T	c.(1723-1725)Ctc>Ttc	p.L575F	CTB-58E17.9_ENST00000579499.1_RNA	NM_005937.3	NP_005928.2	P55198	AF17_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	575					regulation of transcription, DNA-dependent	nucleus	protein binding|zinc ion binding			breast(3)|lung(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	8	Breast(7;4.43e-21)					CAGCACCCCTCTCTCCTCCAG	0.657000			T	MLL	AL								25	61					0	0	1	0	0
ANKRD30A	91074	broad.mit.edu	37	10	37430948	37430948	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr10:37430948C>G	ENST00000374660.1	+	7	1054	c.955C>G	c.(955-957)Cca>Gca	p.P319A	ANKRD30A_ENST00000361713.1_Missense_Mutation_p.P319A|ANKRD30A_ENST00000602533.1_Missense_Mutation_p.P319A			Q9BXX3	AN30A_HUMAN	ankyrin repeat domain 30A	375						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity			NS(1)|breast(8)|endometrium(14)|kidney(21)|large_intestine(13)|lung(70)|ovary(8)|pancreas(1)|prostate(3)|skin(15)|stomach(1)|urinary_tract(3)	158						ATTTACGTGGCCAGCAAAAGG	0.423000													4	124					0	0	1	0	0
ETV7	51513	broad.mit.edu	37	6	36343733	36343733	+	Silent	SNP	G	G	A			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr6:36343733G>A	ENST00000339796.5	-	3	1067	c.222C>T	c.(220-222)tgC>tgT	p.C74C	ETV7_ENST00000340181.4_Silent_p.C74C|ETV7_ENST00000538992.1_Intron|ETV7_ENST00000373738.1_Intron|ETV7_ENST00000373737.4_Silent_p.C74C	NM_001207035.1	NP_001193964.1	Q9Y603	ETV7_HUMAN	ets variant 7	74	PNT.				organ morphogenesis|transcription from RNA polymerase II promoter	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(2)|ovary(1)|skin(4)	10						GCTCCGCGGTGCATGGCAGAG	0.652000													22	33					0	0	1	0	0
MTFR1	9650	broad.mit.edu	37	8	66617057	66617057	+	Missense_Mutation	SNP	A	A	G			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr8:66617057A>G	ENST00000262146.4	+	5	536	c.410A>G	c.(409-411)aAt>aGt	p.N137S	MTFR1_ENST00000458689.2_Missense_Mutation_p.N104S|MTFR1_ENST00000517944.1_3'UTR	NM_014637.3	NP_055452.3	Q15390	MTFR1_HUMAN	mitochondrial fission regulator 1	137						mitochondrion|plasma membrane				cervix(1)|endometrium(1)|kidney(1)|large_intestine(5)|lung(1)|pancreas(1)|urinary_tract(1)	11			Epithelial(68;0.0526)|BRCA - Breast invasive adenocarcinoma(89;0.156)|all cancers(69;0.171)|OV - Ovarian serous cystadenocarcinoma(28;0.194)			GCGCTGGCAAATGAGGAAGCA	0.493000													38	34					0	0	1	0	0
PRUNE2	158471	broad.mit.edu	37	9	79322065	79322065	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr9:79322065C>T	ENST00000428286.1	-	8	5248	c.4048G>A	c.(4048-4050)Gtt>Att	p.V1350I	PRUNE2_ENST00000376718.3_Missense_Mutation_p.V1709I			Q8WUY3	PRUN2_HUMAN	prune homolog 2 (Drosophila)	1709					apoptosis|G1 phase|induction of apoptosis	cytoplasm	metal ion binding|pyrophosphatase activity			endometrium(1)|kidney(4)|large_intestine(3)|lung(7)|prostate(1)	16						TCCTCAGCAACGTGGCAGTTG	0.443000													28	32					0	0	1	0	0
KCNN3	3782	broad.mit.edu	37	1	154842199	154842200	+	In_Frame_Ins	INS	-	-	GCT	rs58327065		TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr1:154842199_154842200insGCT	ENST00000271915.3	-	1	556_557	c.241_242insAGC	c.(241-243)acc>AGCacc	p.80_81insS		NM_002249.5	NP_002240.3	Q9UGI6	KCNN3_HUMAN	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	80	Poly-Gln.					integral to membrane	calmodulin binding	p.Q80_P81insQQ(2)		cervix(1)|endometrium(3)|kidney(2)|large_intestine(6)|lung(11)|prostate(4)|skin(1)	28	all_lung(78;2.29e-27)|all_hematologic(923;0.088)|Hepatocellular(266;0.108)|all_neural(408;0.245)		BRCA - Breast invasive adenocarcinoma(34;0.00819)			GGGATGCGGTGgctgctgctgc	0.698													3	4	---	---	---	---					
AC019118.2	0	broad.mit.edu	37	2	2910744	2910744	+	RNA	DEL	C	C	-			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr2:2910744delC	ENST00000457478.1	-	0	594																											cagccactcacccctacacct	0.692													2	4	---	---	---	---					
CAMK2B	816	broad.mit.edu	37	7	44273998	44273998	+	Frame_Shift_Del	DEL	A	A	-			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr7:44273998delA	ENST00000395749.2	-	15	1198	c.1122delT	c.(1120-1122)ccfs	p.P374fs	CAMK2B_ENST00000258682.6_Frame_Shift_Del_p.P349fs|CAMK2B_ENST00000440254.2_Frame_Shift_Del_p.P374fs|CAMK2B_ENST00000457475.1_Frame_Shift_Del_p.P350fs|CAMK2B_ENST00000502837.2_Frame_Shift_Del_p.P245fs|CAMK2B_ENST00000395747.2_Frame_Shift_Del_p.P350fs|CAMK2B_ENST00000358707.3_Frame_Shift_Del_p.P350fs|CAMK2B_ENST00000353625.4_Intron|CAMK2B_ENST00000350811.3_Frame_Shift_Del_p.P374fs|CAMK2B_ENST00000347193.4_Intron|CAMK2B_ENST00000346990.4_Intron	NM_001220.4	NP_001211.3	Q13554	KCC2B_HUMAN	calcium/calmodulin-dependent protein kinase II beta	374					interferon-gamma-mediated signaling pathway|synaptic transmission	cytosol|endocytic vesicle membrane|nucleoplasm|plasma membrane	ATP binding|calmodulin binding|calmodulin-dependent protein kinase activity			cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|lung(6)|ovary(2)|skin(1)	18						CCAGGGCGGCAGGAGGAAGCG	0.617													2	4	---	---	---	---					
HNRNPUL2	221092	broad.mit.edu	37	11	62488846	62488846	+	Frame_Shift_Del	DEL	A	A	-			TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chr11:62488846delA	ENST00000301785.5	-	9	1724	c.1532delT	c.(1531-1533)tafs	p.L511fs	RP11-831H9.16_ENST00000403734.2_Frame_Shift_Del_p.L511fs	NM_001079559.2	NP_001073027.1	Q1KMD3	HNRL2_HUMAN	heterogeneous nuclear ribonucleoprotein U-like 2	511					cell killing	nucleus	ATP binding|nucleic acid binding			NS(1)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(10)|pancreas(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	20						TTGCTGAACTAAAAGGTCTCG	0.413													77	144	---	---	---	---					
SRPX	8406	broad.mit.edu	37	X	38079976	38079978	+	In_Frame_Del	DEL	GCA	GCA	-	rs72445954		TCGA-QR-A70H-01A-12D-A35D-08	TCGA-QR-A70H-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fbafc85e-deff-46cd-a40f-479b9dc92a60	31c6fa50-200a-46c1-a546-61b52592fd8f	g.chrX:38079976_38079978delGCA	ENST00000378533.3	-	1	174_176	c.68_70delTGC	c.(67-72)cgc>c	p.LR23del	SRPX_ENST00000343800.6_Intron|TM4SF2_ENST00000465127.1_Intron|SRPX_ENST00000432886.2_In_Frame_Del_p.LR23del|SRPX_ENST00000544439.1_In_Frame_Del_p.LR23del|SRPX_ENST00000538295.1_In_Frame_Del_p.LR23del	NM_006307.4	NP_006298.1	P78539	SRPX_HUMAN	sushi-repeat containing protein, X-linked	23			Missing.		cell adhesion	cell surface|membrane		p.L23delL(2)		autonomic_ganglia(1)|breast(2)|endometrium(5)|large_intestine(5)|lung(10)|prostate(2)	25						GGCGGGACGCgcagcagcagcag	0.729											OREG0019726	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	5	---	---	---	---					
