Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ADAM21P1	0	broad.mit.edu	37	14	70713782	70713782	+	RNA	SNP	A	A	G	rs114580810	by1000genomes	TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr14:70713782A>G	ENST00000530196.1	-	0	736					NR_003951.1																						GTCACCAGCAAATTTTGGTTC	0.443000													3	73					0	0	1	0	0
DNAI2	64446	broad.mit.edu	37	17	72285858	72285858	+	Nonsense_Mutation	SNP	C	C	A			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr17:72285858C>A	ENST00000579490.1	+	4	899	c.764C>A	c.(763-765)tCa>tAa	p.S255*	DNAI2_ENST00000311014.6_Nonsense_Mutation_p.S198*|DNAI2_ENST00000446837.2_Nonsense_Mutation_p.S198*|DNAI2_ENST00000307504.5_Nonsense_Mutation_p.S55*|DNAI2_ENST00000582036.1_Nonsense_Mutation_p.S198*			Q9GZS0	DNAI2_HUMAN	dynein, axonemal, intermediate chain 2	198					cilium assembly	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	microtubule motor activity			breast(1)|central_nervous_system(1)|endometrium(4)|large_intestine(6)|liver(2)|lung(19)|ovary(3)|upper_aerodigestive_tract(1)|urinary_tract(2)	39						AGCAGCGATTCATACATCTGG	0.637000									Kartagener syndrome				3	45					1	1	1	1	0
RNF17	56163	broad.mit.edu	37	13	25399864	25399864	+	Silent	SNP	T	T	C			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr13:25399864T>C	ENST00000255324.5	+	16	2251	c.2199T>C	c.(2197-2199)tgT>tgC	p.C733C	RNF17_ENST00000381921.1_Silent_p.C733C	NM_001184993.1|NM_031277.2	NP_001171922.1|NP_112567.2	Q9BXT8	RNF17_HUMAN	ring finger protein 17	733	Tudor 1.				multicellular organismal development	cytoplasm|nucleus	hydrolase activity, acting on ester bonds|nucleic acid binding|zinc ion binding			NS(1)|breast(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(15)|ovary(1)|prostate(3)|skin(6)	36		Lung SC(185;0.0225)|Breast(139;0.077)		all cancers(112;0.0114)|OV - Ovarian serous cystadenocarcinoma(117;0.0311)|Epithelial(112;0.0524)		ATCAAGCCTGTGTAGCTAAAT	0.363000													14	73					0	0	1	0	0
PCDHB6	0	broad.mit.edu	37	5	140530109	140530109	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr5:140530109C>T	ENST00000231136.1	+	1	271	c.271C>T	c.(271-273)Cgg>Tgg	p.R91W	PCDHB6_ENST00000543635.1_5'UTR	NM_018939.2	NP_061762.1	Q9Y5E3	PCDB6_HUMAN		91	Cadherin 1.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to plasma membrane	calcium ion binding			cervix(1)|endometrium(14)|kidney(6)|large_intestine(16)|liver(1)|lung(33)|ovary(1)|pancreas(2)|prostate(1)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	84			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			AAAACTGGACCGGGAGGAGCT	0.507000													13	57					0	0	1	0	0
VPS54	51542	broad.mit.edu	37	2	64199342	64199342	+	Missense_Mutation	SNP	G	G	C			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr2:64199342G>C	ENST00000354504.3	-	2	653	c.64C>G	c.(64-66)Cct>Gct	p.P22A	VPS54_ENST00000272322.4_Missense_Mutation_p.P139A|VPS54_ENST00000409558.3_Missense_Mutation_p.P127A			Q9P1Q0	VPS54_HUMAN	vacuolar protein sorting 54 homolog (S. cerevisiae)	139					protein transport|retrograde transport, endosome to Golgi					endometrium(3)|kidney(4)|large_intestine(8)|lung(10)|ovary(1)|upper_aerodigestive_tract(1)	27						TCTTTAGGAGGACAAATATTC	0.289000													14	58					0	0	1	0	0
DKK3	27122	broad.mit.edu	37	11	12020296	12020296	+	Missense_Mutation	SNP	A	A	T			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr11:12020296A>T	ENST00000396505.2	-	4	620	c.382T>A	c.(382-384)Ttt>Att	p.F128I	DKK3_ENST00000525493.1_Missense_Mutation_p.F128I|DKK3_ENST00000326932.4_Missense_Mutation_p.F128I|DKK3_ENST00000527132.1_Intron|DKK3_ENST00000450094.2_Intron	NM_015881.5	NP_056965.3	Q9UBP4	DKK3_HUMAN	dickkopf WNT signaling pathway inhibitor 3	128					adrenal gland development|anatomical structure morphogenesis|negative regulation of aldosterone biosynthetic process|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of cortisol biosynthetic process|negative regulation of transcription, DNA-dependent|Wnt receptor signaling pathway	extracellular space				breast(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|ovary(1)|pancreas(1)	8				Epithelial(150;0.000502)		GTCTCTGAAAAGACCATTTGT	0.418000													30	37					0	0	1	0	0
FGD6	55785	broad.mit.edu	37	12	95528532	95528532	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr12:95528532T>C	ENST00000343958.4	-	8	3288	c.3065A>G	c.(3064-3066)tAc>tGc	p.Y1022C	FGD6_ENST00000549499.1_Missense_Mutation_p.Y1022C|FGD6_ENST00000546711.1_Missense_Mutation_p.Y1022C	NM_018351.3	NP_060821.3	Q6ZV73	FGD6_HUMAN	FYVE, RhoGEF and PH domain containing 6	1022	DH.				actin cytoskeleton organization|filopodium assembly|regulation of Cdc42 GTPase activity|regulation of cell shape	cytoskeleton|Golgi apparatus|lamellipodium|ruffle	metal ion binding|Rho guanyl-nucleotide exchange factor activity|small GTPase binding			breast(3)|cervix(1)|endometrium(6)|kidney(3)|large_intestine(14)|liver(1)|lung(12)|ovary(3)|prostate(3)|skin(6)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	56						CAACAGCCTGTACTGGGGGAT	0.517000													12	15					0	0	1	0	0
PCMTD1	115294	broad.mit.edu	37	8	52732912	52732912	+	Nonstop_Mutation	SNP	T	T	G			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr8:52732912T>G	ENST00000360540.5	-	7	1479	c.1073A>C	c.(1072-1074)tAa>tCa	p.*358S	PCMTD1_ENST00000544451.1_Nonstop_Mutation_p.*282S|PCMTD1_ENST00000522514.1_Nonstop_Mutation_p.*358S|PCMTD1_ENST00000519559.1_5'UTR	NM_052937.2	NP_443169.2	Q96MG8	PCMD1_HUMAN	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0						cytoplasm	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity			NS(2)|endometrium(1)|kidney(3)|large_intestine(3)|lung(17)|prostate(2)|skin(8)|soft_tissue(1)	37		Lung NSC(129;0.0795)|all_lung(136;0.144)				TGATCTAAGTTATTTGTCTCT	0.338000													4	55					0	0	1	0	0
PCDHB4	0	broad.mit.edu	37	5	140502263	140502263	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr5:140502263G>A	ENST00000194152.1	+	1	683	c.683G>A	c.(682-684)cGa>cAa	p.R228Q		NM_018938.2	NP_061761.1	Q9Y5E5	PCDB4_HUMAN		228	Cadherin 2.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	cytoplasm|integral to plasma membrane|intermediate filament cytoskeleton	calcium ion binding			autonomic_ganglia(1)|breast(2)|endometrium(4)|kidney(2)|large_intestine(12)|lung(35)|ovary(1)|pancreas(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(1)	67			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			GTCATGGTTCGAATCCTGATC	0.537000													34	36					0	0	1	0	0
C8orf37	157657	broad.mit.edu	37	8	96264494	96264494	+	Missense_Mutation	SNP	C	C	T	rs139137766	byFrequency	TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr8:96264494C>T	ENST00000286688.5	-	5	403	c.392G>A	c.(391-393)cGt>cAt	p.R131H		NM_177965.3	NP_808880.1	Q96NL8	CH037_HUMAN	chromosome 8 open reading frame 37	131										kidney(1)|large_intestine(1)|lung(5)	7	Breast(36;3.41e-05)					GGCTATACAACGCAGATGGTC	0.328000													5	79					0	0	1	0	0
FBXO21	23014	broad.mit.edu	37	12	117595766	117595766	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr12:117595766C>G	ENST00000427718.2	-	10	1503	c.1429G>C	c.(1429-1431)Gag>Cag	p.E477Q	FBXO21_ENST00000330622.5_Missense_Mutation_p.E484Q	NM_015002.2|NM_033624.2	NP_055817.1|NP_296373.1	O94952	FBX21_HUMAN	F-box protein 21	484					ubiquitin-dependent protein catabolic process	ubiquitin ligase complex	ubiquitin-protein ligase activity			breast(4)|endometrium(3)|kidney(2)|large_intestine(6)|lung(8)|pancreas(1)|upper_aerodigestive_tract(2)|urinary_tract(3)	29	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)			BRCA - Breast invasive adenocarcinoma(302;0.0291)		CCCACCTCCTCCTTTTTGCGC	0.582000													96	95					0	0	1	0	0
CYP11B1	0	broad.mit.edu	37	8	143961139	143961139	+	Missense_Mutation	SNP	C	C	A			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr8:143961139C>A	ENST00000292427.4	-	1	123	c.91G>T	c.(91-93)Gtc>Ttc	p.V31F	CYP11B1_ENST00000377675.3_Missense_Mutation_p.V31F|CYP11B1_ENST00000517471.1_Missense_Mutation_p.V31F	NM_000497.3	NP_000488.3	P15538	C11B1_HUMAN	cytochrome P450, family 11, subfamily B, polypeptide 1	31					aldosterone biosynthetic process|cellular response to hormone stimulus|cellular response to potassium ion|cortisol biosynthetic process|glucose homeostasis|immune response|regulation of blood pressure|response to stress|xenobiotic metabolic process	mitochondrial inner membrane	electron carrier activity|steroid 11-beta-monooxygenase activity			central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(10)|lung(36)|ovary(4)|prostate(3)|skin(2)|upper_aerodigestive_tract(2)	67	all_cancers(97;4.74e-11)|all_epithelial(106;2.06e-08)|Lung NSC(106;0.000228)|all_lung(105;0.000633)|Medulloblastoma(13;0.00276)|all_neural(13;0.00559)|Ovarian(258;0.0254)|Acute lymphoblastic leukemia(118;0.155)				Mitotane(DB00648)	GTCCTGGGGACCCGGGCGGCT	0.642000									Familial Hyperaldosteronism type I				29	20					1.75199e-13	1.83162e-13	1	1	0
CCT6B	10693	broad.mit.edu	37	17	33269552	33269552	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr17:33269552T>C	ENST00000314144.5	-	7	951	c.836A>G	c.(835-837)gAc>gGc	p.D279G	CCT6B_ENST00000436961.3_Missense_Mutation_p.D234G|CCT6B_ENST00000421975.3_Missense_Mutation_p.D242G	NM_006584.3	NP_006575.2	Q92526	TCPW_HUMAN	chaperonin containing TCP1, subunit 6B (zeta 2)	279					chaperone-mediated protein complex assembly|protein folding|spermatogenesis	cytoplasm	ATP binding|protein transporter activity|unfolded protein binding			NS(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(3)|lung(7)|ovary(1)|pancreas(1)	20		Ovarian(249;0.17)				ACAGACTTTGTCCTTCAGGTC	0.294000													17	2					0	0	1	0	0
BCHE	590	broad.mit.edu	37	3	165547533	165547533	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr3:165547533G>A	ENST00000264381.3	-	2	1455	c.1289C>T	c.(1288-1290)gCc>gTc	p.A430V	BCHE_ENST00000540653.1_Intron	NM_000055.2	NP_000046.1	P06276	CHLE_HUMAN	butyrylcholinesterase	430					choline metabolic process|cocaine metabolic process|synaptic transmission, cholinergic	endoplasmic reticulum lumen|extracellular space|membrane	acetylcholinesterase activity|beta-amyloid binding|carboxylesterase activity|cholinesterase activity|enzyme binding			breast(1)|endometrium(2)|kidney(1)|large_intestine(10)|lung(34)|ovary(4)|pancreas(2)|stomach(1)	55					Ambenonium(DB01122)|Atropine(DB00572)|Bambuterol(DB01408)|Chlorpromazine(DB00477)|Choline(DB00122)|Cinnarizine(DB00568)|Demecarium bromide(DB00944)|Dibucaine(DB00527)|Donepezil(DB00843)|Echothiophate Iodide(DB01057)|Edrophonium(DB01010)|Ethopropazine(DB00392)|Etomidate(DB00292)|Galantamine(DB00674)|Hexafluronium bromide(DB00941)|Isoflurophate(DB00677)|Mefloquine(DB00358)|Mivacurium(DB01226)|Neostigmine(DB01400)|Pancuronium(DB01337)|Pralidoxime(DB00733)|Procainamide(DB01035)|Pyridostigmine(DB00545)|Rivastigmine(DB00989)|Succinylcholine(DB00202)|Terbutaline(DB00871)|Trimethaphan(DB01116)	GAACTCCAAGGCAGGGCATAT	0.438000													6	26					0	0	1	0	0
IQSEC2	23096	broad.mit.edu	37	X	53279664	53279664	+	Silent	SNP	G	G	A			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chrX:53279664G>A	ENST00000396435.3	-	5	2294	c.2094C>T	c.(2092-2094)agC>agT	p.S698S	IQSEC2_ENST00000375365.2_Silent_p.S493S|IQSEC2_ENST00000375368.5_Silent_p.S688S	NM_001111125.2	NP_001104595.1	Q5JU85	IQEC2_HUMAN	IQ motif and Sec7 domain 2	688					regulation of ARF protein signal transduction	cytoplasm	ARF guanyl-nucleotide exchange factor activity			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(4)|lung(10)|ovary(4)|skin(1)	29						AGCTCTCAAGGCTCTCGTTAT	0.617000													4	40					0	0	1	0	0
MRPL46	26589	broad.mit.edu	37	15	89010473	89010473	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr15:89010473G>A	ENST00000312475.4	-	1	177	c.136C>T	c.(136-138)Cgc>Tgc	p.R46C		NM_022163.3	NP_071446.2	Q9H2W6	RM46_HUMAN	mitochondrial ribosomal protein L46	46						mitochondrion|ribosome	hydrolase activity			central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(1)	5	Lung NSC(78;0.203)		BRCA - Breast invasive adenocarcinoma(143;0.188)			CCCAACAAGCGCCATGGGGAT	0.652000													13	13					0	0	1	0	0
PSG7	5676	broad.mit.edu	37	19	43441282	43441282	+	RNA	SNP	T	T	A			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr19:43441282T>A	ENST00000406070.2	-	0	43				PSG7_ENST00000471557.1_RNA|PSG7_ENST00000446844.3_RNA	NM_002783.2	NP_002774.2	Q13046	PSG7_HUMAN	pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)						female pregnancy	extracellular region							Prostate(69;0.00682)				GGATCCAGAATCTTCCTGAGC	0.597000													3	43					0	0	1	0	0
ZNF844	284391	broad.mit.edu	37	19	12187443	12187443	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr19:12187443C>G	ENST00000439326.3	+	4	1683	c.1508C>G	c.(1507-1509)cCt>cGt	p.P503R	ZNF844_ENST00000441304.2_3'UTR	NM_001136501.1	NP_001129973.1	Q08AG5	ZN844_HUMAN	zinc finger protein 844	503					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding	p.P503R(1)		NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|kidney(2)|lung(1)|prostate(1)	10						GAGAGAAACCCTATGAGTGTA	0.413000													4	55					0	0	1	0	0
HSPG2	3339	broad.mit.edu	37	1	22207315	22207315	+	Frame_Shift_Del	DEL	C	C	-			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr1:22207315delC	ENST00000374695.3	-	15	1911	c.1832delG	c.(1831-1833)gcfs	p.G612fs		NM_005529.5	NP_005520.4	P98160	PGBM_HUMAN	heparan sulfate proteoglycan 2	612	Laminin IV type A 1.				angiogenesis|cell adhesion|lipid metabolic process|lipoprotein metabolic process	basement membrane|extracellular space|plasma membrane	protein C-terminus binding			breast(6)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(9)|large_intestine(15)|liver(1)|lung(44)|ovary(10)|pancreas(1)|prostate(10)|skin(9)|upper_aerodigestive_tract(3)|urinary_tract(3)	127		Colorectal(325;3.46e-05)|all_lung(284;7.93e-05)|Lung NSC(340;8.71e-05)|Renal(390;0.000219)|Breast(348;0.00222)|Ovarian(437;0.00308)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0498)|OV - Ovarian serous cystadenocarcinoma(117;1.14e-26)|Colorectal(126;4.18e-07)|COAD - Colon adenocarcinoma(152;1.82e-05)|GBM - Glioblastoma multiforme(114;3.13e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000756)|STAD - Stomach adenocarcinoma(196;0.00656)|KIRC - Kidney renal clear cell carcinoma(1967;0.00942)|READ - Rectum adenocarcinoma(331;0.0721)|Lung(427;0.223)	Becaplermin(DB00102)|Palifermin(DB00039)	CAGGGAGCCGCCATAGGAGTC	0.637													2	4	---	---	---	---					
ANKRD20A12P	0	broad.mit.edu	37	1	142716575	142716578	+	RNA	DEL	AAAC	AAAC	-			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr1:142716575_142716578delAAAC	ENST00000595144.1	-	0	418																											catctcagaaaaacaaacaaacaa	0.422													7	170	---	---	---	---					
CTC-338M12.9	0	broad.mit.edu	37	5	180708776	180708777	+	RNA	INS	-	-	G	rs140221514		TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr5:180708776_180708777insG	ENST00000412295.2	+	0	238																											gggcggtaggagggggctggag	0.728													4	4	---	---	---	---					
NF1	4763	broad.mit.edu	37	17	29653263	29653263	+	Frame_Shift_Del	DEL	C	C	-			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr17:29653263delC	ENST00000358273.4	+	37	5644	c.5261delC	c.(5260-5262)ttfs	p.S1754fs	NF1_ENST00000581113.2_3'UTR|NF1_ENST00000356175.3_Frame_Shift_Del_p.S1733fs	NM_001042492.2	NP_001035957.1	P21359	NF1_HUMAN	neurofibromin 1	1754					actin cytoskeleton organization|adrenal gland development|artery morphogenesis|camera-type eye morphogenesis|cerebral cortex development|collagen fibril organization|forebrain astrocyte development|forebrain morphogenesis|heart development|liver development|MAPKKK cascade|metanephros development|myelination in peripheral nervous system|negative regulation of cell migration|negative regulation of endothelial cell proliferation|negative regulation of MAP kinase activity|negative regulation of MAPKKK cascade|negative regulation of neuroblast proliferation|negative regulation of oligodendrocyte differentiation|negative regulation of transcription factor import into nucleus|osteoblast differentiation|phosphatidylinositol 3-kinase cascade|pigmentation|positive regulation of adenylate cyclase activity|positive regulation of neuron apoptosis|Ras protein signal transduction|regulation of blood vessel endothelial cell migration|regulation of bone resorption|response to hypoxia|smooth muscle tissue development|spinal cord development|sympathetic nervous system development|visual learning|wound healing	axon|cytoplasm|dendrite|intrinsic to internal side of plasma membrane|nucleus	protein binding|Ras GTPase activator activity	p.0?(8)|p.?(3)	NF1/ACCN1(2)	autonomic_ganglia(12)|breast(11)|central_nervous_system(72)|cervix(6)|endometrium(12)|haematopoietic_and_lymphoid_tissue(59)|kidney(9)|large_intestine(39)|liver(1)|lung(80)|ovary(20)|pancreas(2)|prostate(2)|skin(8)|soft_tissue(249)|stomach(2)|thyroid(1)|upper_aerodigestive_tract(5)|urinary_tract(9)	599		all_cancers(10;1.29e-12)|all_epithelial(10;0.00347)|all_hematologic(16;0.00556)|Acute lymphoblastic leukemia(14;0.00593)|Breast(31;0.014)|Myeloproliferative disorder(56;0.0255)|all_lung(9;0.0321)|Lung NSC(157;0.0659)		UCEC - Uterine corpus endometrioid carcinoma (4;4.38e-05)|all cancers(4;1.64e-26)|Epithelial(4;9.15e-23)|OV - Ovarian serous cystadenocarcinoma(4;3.58e-21)|GBM - Glioblastoma multiforme(4;0.00146)		ACCAAAGTTTCTATTAAAGTA	0.423			"""D, Mis, N, F, S, O"""		"""neurofibroma, glioma"""	"""neurofibroma, glioma"""			Neurofibromatosis, type 1	TCGA GBM(6;<1E-08)|TSP Lung(7;0.0071)|TCGA Ovarian(3;0.0088)			18	2	---	---	---	---					
IGLV3-12	0	broad.mit.edu	37	22	23114748	23114749	+	RNA	INS	-	-	T	rs58165270		TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chr22:23114748_23114749insT	ENST00000390313.2	+	0	55																											CCATCCTCTCCTTTTTTTTTTT	0.495													4	3	---	---	---	---					
RP11-308D16.4	0	broad.mit.edu	37	X	136030245	136030245	+	RNA	DEL	T	T	-			TCGA-QR-A70V-01A-11D-A35D-08	TCGA-QR-A70V-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5873ba50-f22c-4a5e-81c5-e2997bee3a8f	08885038-9c83-4bfc-9c3b-c3eb2b8c67e2	g.chrX:136030245delT	ENST00000424306.1	+	0	2052																											GAGAACCTGCTTTTTTTTTTT	0.438													4	5	---	---	---	---					
