Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
TTN	7273	broad.mit.edu	37	2	179455966	179455966	+	Silent	SNP	T	T	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr2:179455966T>A	ENST00000589042.1	-	304	60710	c.60486A>T	c.(60484-60486)gtA>gtT	p.V20162V	TTN-AS1_ENST00000419746.1_RNA|TTN_ENST00000460472.2_Silent_p.V11097V|TTN-AS1_ENST00000585451.1_RNA|TTN-AS1_ENST00000589907.1_RNA|TTN-AS1_ENST00000589234.1_RNA|TTN-AS1_ENST00000590807.1_RNA|TTN_ENST00000359218.5_Silent_p.V11222V|TTN_ENST00000342175.6_Silent_p.V11289V|TTN-AS1_ENST00000590743.1_RNA|TTN_ENST00000342992.6_Silent_p.V17594V|TTN-AS1_ENST00000592750.1_RNA|TTN-AS1_ENST00000592630.1_RNA|TTN-AS1_ENST00000456053.1_RNA|TTN-AS1_ENST00000592689.1_RNA|TTN-AS1_ENST00000591332.1_RNA|TTN_ENST00000591111.1_Silent_p.V18521V|TTN-AS1_ENST00000590932.1_RNA|TTN-AS1_ENST00000586452.1_RNA	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	18521	Fibronectin type-III 46.						ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			GATGTACGGCTACTGTTTTGC	0.438000													55	113					0	0	1	0	0
KIF2B	84643	broad.mit.edu	37	17	51901892	51901892	+	Missense_Mutation	SNP	A	A	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr17:51901892A>C	ENST00000268919.4	+	1	1654	c.1498A>C	c.(1498-1500)Aca>Cca	p.T500P		NM_032559.4	NP_115948.4	Q8N4N8	KIF2B_HUMAN	kinesin family member 2B	500				T -> A (in Ref. 1; AAK20830).	blood coagulation|cell division|microtubule depolymerization|microtubule-based movement|mitotic prometaphase|regulation of chromosome segregation	condensed chromosome kinetochore|cytosol|microtubule|microtubule organizing center|nucleolus|spindle	ATP binding|microtubule motor activity			NS(1)|breast(2)|endometrium(7)|kidney(2)|large_intestine(15)|lung(58)|ovary(5)|prostate(4)|skin(7)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	104						CAGCAAACTCACACTGGTGCT	0.502000													21	18					0	0	1	0	0
TTLL3	26140	broad.mit.edu	37	3	9859359	9859359	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr3:9859359C>T	ENST00000547186.1	+	5	562	c.346C>T	c.(346-348)Ccg>Tcg	p.P116S	TTLL3_ENST00000397241.1_5'UTR|TTLL3_ENST00000427853.3_5'UTR|ARPC4-TTLL3_ENST00000397256.1_Missense_Mutation_p.P210S|TTLL3_ENST00000426895.4_Missense_Mutation_p.P259S	NM_001025930.3	NP_001021100.3	Q9Y4R7	TTLL3_HUMAN	tubulin tyrosine ligase-like family, member 3	116					axoneme assembly|cilium assembly|protein polyglycylation	cilium axoneme|cytoplasm|microtubule	protein-glycine ligase activity, initiating|tubulin-tyrosine ligase activity	p.P116S(1)		central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|lung(10)|ovary(1)|prostate(2)|skin(1)	26	Medulloblastoma(99;0.227)					CCGGAATTTGCCGTGGTTTGA	0.547000													4	160					0	0	1	0	0
POMT2	29954	broad.mit.edu	37	14	77751945	77751945	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr14:77751945G>A	ENST00000261534.4	-	13	1565	c.1363C>T	c.(1363-1365)Cgg>Tgg	p.R455W		NM_013382.5	NP_037514.2	Q9UKY4	POMT2_HUMAN	protein-O-mannosyltransferase 2	455	MIR 2.				protein O-linked glycosylation	endoplasmic reticulum membrane|integral to membrane	dolichyl-phosphate-mannose-protein mannosyltransferase activity|metal ion binding			breast(2)|endometrium(2)|large_intestine(1)|liver(1)|lung(5)|ovary(1)|prostate(1)|skin(1)	14			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0292)		ACCTCAATCCGCCAGAAATCA	0.443000													5	563					0	0	1	0	0
TRBV5-7	0	broad.mit.edu	37	7	142111680	142111680	+	RNA	SNP	A	A	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr7:142111680A>C	ENST00000390378.1	-	0	55																											TCCAGCGTCCACTGGGCCTGT	0.552000													4	140					0	0	1	0	0
RP11-1166P10.6	0	broad.mit.edu	37	16	32070612	32070612	+	RNA	SNP	A	A	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr16:32070612A>C	ENST00000566806.1	-	0	499																											GGTCTCCTGCAAGGCTTCTGG	0.552000													4	69					0	0	1	0	0
SPTBN2	6712	broad.mit.edu	37	11	66457285	66457285	+	Silent	SNP	C	C	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr11:66457285C>A	ENST00000533211.1	-	29	6271	c.5940G>T	c.(5938-5940)gcG>gcT	p.A1980A	SPTBN2_ENST00000529997.1_Silent_p.A1980A|SPTBN2_ENST00000309996.2_Silent_p.A1980A			O15020	SPTN2_HUMAN	spectrin, beta, non-erythrocytic 2	1980					actin filament capping|axon guidance|cell death|vesicle-mediated transport	cytosol|spectrin	actin binding|structural constituent of cytoskeleton			autonomic_ganglia(1)|breast(1)|central_nervous_system(4)|cervix(1)|endometrium(10)|kidney(5)|large_intestine(15)|liver(1)|lung(22)|ovary(2)|pancreas(1)|prostate(3)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(1)	74						CCTCCTCGGCCGCATAGTGGC	0.602000													53	1					4.88482e-21	5.65611e-21	1	1	0
PNPT1	87178	broad.mit.edu	37	2	55900135	55900135	+	Silent	SNP	T	T	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr2:55900135T>C	ENST00000447944.2	-	9	845	c.759A>G	c.(757-759)caA>caG	p.Q253Q		NM_033109.3	NP_149100.2	Q8TCS8	PNPT1_HUMAN	polyribonucleotide nucleotidyltransferase 1	253					mRNA catabolic process|RNA processing	plasma membrane	3'-5'-exoribonuclease activity|polyribonucleotide nucleotidyltransferase activity|RNA binding			cervix(1)|endometrium(3)|kidney(1)|large_intestine(10)|lung(9)|skin(2)|urinary_tract(1)	27			LUSC - Lung squamous cell carcinoma(58;0.127)|Lung(47;0.132)			GAATTATTTGTTGGGTATATT	0.388000													39	94					0	0	1	0	0
FAM193B	54540	broad.mit.edu	37	5	176952164	176952164	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr5:176952164C>T	ENST00000329540.5	-	9	3025	c.196G>A	c.(196-198)Gca>Aca	p.A66T	FAM193B_ENST00000514747.1_Missense_Mutation_p.A440T|FAM193B_ENST00000443375.2_Missense_Mutation_p.A407T			Q6IPW0	Q6IPW0_HUMAN	family with sequence similarity 193, member B	116										kidney(1)|large_intestine(3)	4						ACACGATTTGCCTGCTTTAGA	0.577000													3	34					0	0	1	0	0
KRT35	3886	broad.mit.edu	37	17	39637289	39637289	+	Missense_Mutation	SNP	C	C	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr17:39637289C>A	ENST00000393989.1	-	1	103	c.61G>T	c.(61-63)Gcc>Tcc	p.A21S	KRT35_ENST00000246639.2_5'UTR	NM_002280.4	NP_002271.3	Q92764	KRT35_HUMAN	keratin 35	21	Head.				anatomical structure morphogenesis	intermediate filament	protein binding|structural molecule activity			NS(1)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(3)|lung(9)|ovary(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	29		Breast(137;0.000286)				CCCCCACTGGCCCCTCCTGGG	0.577000													13	43					0.00185496	0.0018981	1	1	0
CLCA1	1179	broad.mit.edu	37	1	86934788	86934788	+	Missense_Mutation	SNP	A	A	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr1:86934788A>C	ENST00000234701.3	+	2	485	c.134A>C	c.(133-135)gAa>gCa	p.E45A	CLCA1_ENST00000394711.1_Missense_Mutation_p.E45A			A8K7I4	CLCA1_HUMAN	chloride channel accessory 1	45					calcium ion transport	extracellular space|integral to plasma membrane	chloride channel activity			NS(1)|breast(3)|endometrium(1)|kidney(3)|large_intestine(9)|lung(14)|ovary(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	38		Lung NSC(277;0.239)		all cancers(265;0.0249)|Epithelial(280;0.0476)		AATGTGCCAGAAGATGAAACA	0.383000													31	0					0	0	1	0	0
CTBP1	1487	broad.mit.edu	37	4	1235191	1235191	+	Translation_Start_Site	SNP	G	G	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr4:1235191G>T	ENST00000510568.1	-	0	520				CTBP1_ENST00000290921.6_Intron|CTBP1_ENST00000382952.3_De_novo_Start_InFrame|CTBP1_ENST00000515690.1_5'UTR			Q13363	CTBP1_HUMAN	C-terminal binding protein 1						interspecies interaction between organisms|negative regulation of cell proliferation|negative regulation of histone H4 acetylation|negative regulation of transcription from RNA polymerase II promoter|positive regulation of histone deacetylation|protein phosphorylation|regulation of cell cycle|regulation of transcription by chromatin organization|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|viral genome replication|white fat cell differentiation	cytoplasm|transcriptional repressor complex	NAD binding|oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor|protein C-terminus binding|protein domain specific binding|transcription factor binding			endometrium(1)|kidney(1)|large_intestine(1)|lung(2)|ovary(1)|skin(1)|urinary_tract(1)	8			OV - Ovarian serous cystadenocarcinoma(23;0.00818)	Colorectal(103;0.2)		aggatccccaggcagaaCCGC	0.527000													23	40					1.22574e-08	1.34831e-08	1	1	0
ATP6V1G3	127124	broad.mit.edu	37	1	198498307	198498307	+	Missense_Mutation	SNP	T	T	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr1:198498307T>A	ENST00000309309.7	-	4	238	c.133A>T	c.(133-135)Agg>Tgg	p.R45W	ATP6V1G3_ENST00000281087.2_Missense_Mutation_p.K29N|ATP6V1G3_ENST00000367381.1_Missense_Mutation_p.K35N|ATP6V1G3_ENST00000489986.1_Missense_Mutation_p.K35N|ATP6V1G3_ENST00000367382.1_Missense_Mutation_p.K29N	NM_133326.1	NP_579872.1	Q96LB4	VATG3_HUMAN	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	0					cellular iron ion homeostasis|insulin receptor signaling pathway|transferrin transport	cytosol|plasma membrane|vacuolar proton-transporting V-type ATPase complex	ATPase binding			central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|lung(3)|prostate(1)	7						ATCGCTTTCCTTTTCCTGAAA	0.254000													18	28					0	0	1	0	0
TAS2R8	50836	broad.mit.edu	37	12	10959260	10959260	+	Missense_Mutation	SNP	T	T	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr12:10959260T>C	ENST00000240615.2	-	1	632	c.320A>G	c.(319-321)tAt>tGt	p.Y107C		NM_023918.1	NP_076407.1	Q9NYW2	TA2R8_HUMAN	taste receptor, type 2, member 8	107					sensory perception of taste	integral to membrane	taste receptor activity			endometrium(2)|kidney(1)|large_intestine(3)|lung(3)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	14						CTTCAGAAAATAGAAGACATT	0.383000													37	35					0	0	1	0	0
FRG1B	0	broad.mit.edu	37	20	29625877	29625877	+	Missense_Mutation	SNP	G	G	A	rs7266938	by1000genomes	TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr20:29625877G>A	ENST00000278882.3	+	5	501	c.121G>A	c.(121-123)Gcc>Acc	p.A41T	FRG1B_ENST00000358464.4_Missense_Mutation_p.A41T|FRG1B_ENST00000439954.2_Missense_Mutation_p.A46T														p.A41T(2)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						GTACAGAATCGCCCTGAAATC	0.358000													7	99					0	0	1	0	0
TERF2	7014	broad.mit.edu	37	16	69404385	69404385	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr16:69404385C>T	ENST00000567296.2	-	5	857	c.841G>A	c.(841-843)Gtg>Atg	p.V281M	TERF2_ENST00000254942.3_Splice_Site|TERF2_ENST00000603068.1_Splice_Site|TERF2_ENST00000569611.2_Splice_Site			Q15554	TERF2_HUMAN	telomeric repeat binding factor 2	239					age-dependent telomere shortening|cell cycle|cellular senescence|negative regulation of telomere maintenance via semi-conservative replication|protection from non-homologous end joining at telomere|protein localization to chromosome, telomeric region|regulation of transcription, DNA-dependent|telomeric loop formation	Golgi apparatus|nuclear telomere cap complex|nucleoplasm	double-stranded telomeric DNA binding|protein C-terminus binding|protein homodimerization activity			NS(2)|breast(1)|large_intestine(3)|lung(1)	7		Ovarian(137;0.101)				CCAAGGCGCACCGTGAGGAGG	0.512000													3	53					0	0	1	0	0
SVOPL	136306	broad.mit.edu	37	7	138313042	138313042	+	Missense_Mutation	SNP	C	C	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr7:138313042C>A	ENST00000421622.1	-	7	778	c.570G>T	c.(568-570)ttG>ttT	p.L190F	SVOPL_ENST00000419765.3_Missense_Mutation_p.L310F|SVOPL_ENST00000288513.5_Missense_Mutation_p.L158F|SVOPL_ENST00000436657.1_Missense_Mutation_p.L158F			Q8N434	SVOPL_HUMAN	SVOP-like	310						integral to membrane	transmembrane transporter activity			NS(1)|endometrium(2)|kidney(1)|large_intestine(5)|lung(4)|ovary(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)	19						AACCACAGACCAAGTCCCGCT	0.562000													17	23					5.01169e-05	5.3784e-05	1	1	0
ACAP3	116983	broad.mit.edu	37	1	1233463	1233463	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr1:1233463G>A	ENST00000354700.5	-	13	1148	c.946C>T	c.(946-948)Cgc>Tgc	p.R316C	ACAP3_ENST00000379037.2_5'UTR|ACAP3_ENST00000353662.3_Missense_Mutation_p.R274C	NM_030649.2	NP_085152.2	Q96P50	ACAP3_HUMAN	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	316	PH.				filopodium assembly|regulation of ARF GTPase activity|signal transduction		ARF GTPase activator activity|cytoskeletal adaptor activity|SH3 domain binding|zinc ion binding			endometrium(3)|lung(9)|skin(1)|upper_aerodigestive_tract(1)	14						GAGCACAGGCGGAGGTCATCC	0.682000													3	19					0	0	1	0	0
SLIT1	6585	broad.mit.edu	37	10	98808821	98808821	+	Silent	SNP	G	G	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr10:98808821G>A	ENST00000266058.4	-	14	1601	c.1356C>T	c.(1354-1356)gaC>gaT	p.D452D	ARHGAP19-SLIT1_ENST00000453547.2_3'UTR|SLIT1_ENST00000371070.4_Silent_p.D452D	NM_003061.2	NP_003052.2	O75093	SLIT1_HUMAN	slit homolog 1 (Drosophila)	452	LRRCT 2.				axon extension involved in axon guidance|forebrain morphogenesis|motor axon guidance|negative chemotaxis|negative regulation of synaptogenesis	cytoplasm|extracellular space	calcium ion binding|Roundabout binding			breast(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(16)|lung(37)|ovary(5)|prostate(4)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	78		Colorectal(252;0.162)		Epithelial(162;2.02e-08)|all cancers(201;1.5e-06)		TGCGCAGGAAGTCTGCCAGCC	0.582000													9	57					0	0	1	0	0
PCDHGA8	0	broad.mit.edu	37	5	140773281	140773281	+	Missense_Mutation	SNP	A	A	G			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr5:140773281A>G	ENST00000398604.2	+	1	901	c.901A>G	c.(901-903)Ata>Gta	p.I301V	PCDHGA5_ENST00000518069.1_Intron|PCDHGA1_ENST00000517417.1_Intron|PCDHGA6_ENST00000517434.1_Intron|PCDHGB3_ENST00000576222.1_Intron|PCDHGA2_ENST00000394576.2_Intron|PCDHGA4_ENST00000571252.1_Intron|PCDHGB1_ENST00000523390.1_Intron|PCDHGB2_ENST00000522605.1_Intron|PCDHGA3_ENST00000253812.6_Intron|PCDHGB4_ENST00000519479.1_Intron|PCDHGA7_ENST00000518325.1_Intron	NM_032088.1	NP_114477.1														endometrium(6)|kidney(6)|large_intestine(6)|lung(30)|ovary(1)|stomach(1)|upper_aerodigestive_tract(1)	51			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			TACTGGGGAAATATCAATAGC	0.388000													3	85					0	0	1	0	0
DIP2C	22982	broad.mit.edu	37	10	445145	445145	+	Missense_Mutation	SNP	G	G	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr10:445145G>C	ENST00000280886.6	-	10	1251	c.1164C>G	c.(1162-1164)ttC>ttG	p.F388L	DIP2C_ENST00000381496.3_Missense_Mutation_p.F281L	NM_014974.2	NP_055789.1	Q9Y2E4	DIP2C_HUMAN	DIP2 disco-interacting protein 2 homolog C (Drosophila)	388						nucleus	catalytic activity|transcription factor binding			breast(8)|endometrium(6)|kidney(10)|large_intestine(13)|lung(26)|ovary(3)|prostate(6)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(4)	81		all_cancers(4;0.00336)|all_lung(4;0.00732)|Lung NSC(4;0.00785)|all_epithelial(10;0.0159)|Colorectal(49;0.235)	OV - Ovarian serous cystadenocarcinoma(33;0.136)	Epithelial(11;0.0123)|all cancers(11;0.0467)|Lung(33;0.0864)|OV - Ovarian serous cystadenocarcinoma(14;0.106)		CATTGTTGGGGAACACCAGTG	0.617000													21	36					0	0	1	0	0
DCDC1	341019	broad.mit.edu	37	11	31086025	31086025	+	Missense_Mutation	SNP	G	G	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr11:31086025G>C	ENST00000597505.1	-	18	2581	c.2582C>G	c.(2581-2583)tCt>tGt	p.S861C	DCDC1_ENST00000437348.1_5'UTR			P59894	DCDC1_HUMAN	doublecortin domain containing 1	0					intracellular signal transduction					central_nervous_system(1)|cervix(1)|endometrium(1)|kidney(2)|large_intestine(4)|lung(17)|pancreas(2)|prostate(1)|skin(1)|stomach(1)	31	Lung SC(675;0.225)					CCTCTGAGCAGAAGCCTTAGG	0.438000													42	38					0	0	1	0	0
ABCA13	154664	broad.mit.edu	37	7	48314395	48314395	+	Missense_Mutation	SNP	G	G	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr7:48314395G>T	ENST00000435803.1	+	17	5156	c.5132G>T	c.(5131-5133)gGc>gTc	p.G1711V		NM_152701.3	NP_689914.2	Q86UQ4	ABCAD_HUMAN	ATP-binding cassette, sub-family A (ABC1), member 13	1711					transport	integral to membrane	ATP binding|ATPase activity			breast(13)|central_nervous_system(8)|endometrium(25)|haematopoietic_and_lymphoid_tissue(4)|kidney(20)|large_intestine(51)|lung(100)|ovary(5)|pancreas(2)|prostate(22)|skin(10)|stomach(3)|upper_aerodigestive_tract(3)|urinary_tract(4)	270						TTGCTTGTTGGCTTGATGGAA	0.393000													16	65					2.5808e-16	2.91167e-16	1	1	0
POLR3B	55703	broad.mit.edu	37	12	106820987	106820987	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr12:106820987C>T	ENST00000228347.4	+	13	1336	c.1114C>T	c.(1114-1116)Ctt>Ttt	p.L372F	POLR3B_ENST00000549195.1_3'UTR|POLR3B_ENST00000539066.1_Missense_Mutation_p.L314F	NM_018082.5	NP_060552.4	Q9NW08	RPC2_HUMAN	polymerase (RNA) III (DNA directed) polypeptide B	372					innate immune response|positive regulation of innate immune response|positive regulation of interferon-beta production|response to virus|termination of RNA polymerase III transcription|transcription elongation from RNA polymerase III promoter	nucleoplasm	DNA binding|DNA-directed RNA polymerase activity|metal ion binding|ribonucleoside binding	p.L372F(2)		breast(2)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(3)|large_intestine(14)|lung(22)|ovary(1)|prostate(3)|skin(3)|urinary_tract(2)	57						TTTATCTCTTCTTTTTGAAGA	0.274000													8	32					0	0	1	0	0
AMER1	139285	broad.mit.edu	37	X	63412784	63412784	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chrX:63412784G>A	ENST00000330258.3	-	2	655	c.383C>T	c.(382-384)cCc>cTc	p.P128L	AMER1_ENST00000403336.1_Missense_Mutation_p.P128L|AMER1_ENST00000374869.3_Missense_Mutation_p.P128L	NM_152424.3	NP_689637.3			APC membrane recruitment protein 1									p.0?(67)									CTGAGAGCTGGGAAATTGGCA	0.552000													19	16					0	0	1	0	0
COL12A1	1303	broad.mit.edu	37	6	75811733	75811733	+	Silent	SNP	T	T	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr6:75811733T>C	ENST00000322507.8	-	57	8760	c.8451A>G	c.(8449-8451)ccA>ccG	p.P2817P	COL12A1_ENST00000345356.6_Silent_p.P1653P|COL12A1_ENST00000416123.2_Silent_p.P2741P|COL12A1_ENST00000483888.2_Silent_p.P2817P	NM_004370.5	NP_004361.3	Q99715	COCA1_HUMAN	collagen, type XII, alpha 1	2817	Triple-helical region (COL2) with 1 imperfection.				cell adhesion|collagen fibril organization|skeletal system development	collagen type XII|extracellular space	extracellular matrix structural constituent conferring tensile strength			breast(7)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(5)|kidney(5)|large_intestine(44)|liver(1)|lung(77)|ovary(7)|prostate(3)|skin(4)|stomach(2)|upper_aerodigestive_tract(4)|urinary_tract(2)	169						CTGGAAGTCCTGGCTCTCCAG	0.458000													4	150					0	0	1	0	0
DCAF17	80067	broad.mit.edu	37	2	172306405	172306405	+	Missense_Mutation	SNP	A	A	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr2:172306405A>T	ENST00000375255.3	+	5	802	c.475A>T	c.(475-477)Act>Tct	p.T159S	DCAF17_ENST00000468592.1_3'UTR|DCAF17_ENST00000539783.1_Missense_Mutation_p.T159S	NM_025000.3	NP_079276.2	Q5H9S7	DCA17_HUMAN	DDB1 and CUL4 associated factor 17	159						CUL4 RING ubiquitin ligase complex|integral to membrane|nucleolus				endometrium(1)|kidney(2)|large_intestine(3)|lung(10)|prostate(1)	17						GAGCTGGGACACTCCTCAAGA	0.338000													3	43					0	0	1	0	0
ZNF394	84124	broad.mit.edu	37	7	99091213	99091213	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr7:99091213C>T	ENST00000337673.6	-	3	1828	c.1625G>A	c.(1624-1626)cGa>cAa	p.R542Q	ZNF394_ENST00000426306.2_3'UTR|ZNF789_ENST00000494186.1_Intron|ZNF789_ENST00000493485.1_Intron	NM_032164.2	NP_115540.2	Q53GI3	ZN394_HUMAN	zinc finger protein 394	542					viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|liver(1)|lung(5)|stomach(1)|urinary_tract(1)	16	all_cancers(62;2.54e-08)|all_epithelial(64;2.55e-09)|Lung NSC(181;0.0053)|all_lung(186;0.00895)|Esophageal squamous(72;0.0166)					TCTTTGGTGTCGGATAAGGTG	0.463000													75	81					0	0	1	0	0
WDR11	55717	broad.mit.edu	37	10	122619631	122619631	+	Missense_Mutation	SNP	G	G	C			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr10:122619631G>C	ENST00000263461.6	+	4	609	c.363G>C	c.(361-363)tgG>tgC	p.W121C		NM_018117.11	NP_060587.8	Q9BZH6	WDR11_HUMAN	WD repeat domain 11	121						integral to membrane				breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(11)|lung(9)|prostate(2)|skin(2)|stomach(5)	38						ATGTTCAGTGGTTGTGGAATC	0.428000													32	87					0	0	1	0	0
CLEC4M	10332	broad.mit.edu	37	19	7831056	7831056	+	Silent	SNP	A	A	G			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr19:7831056A>G	ENST00000327325.5	+	4	865	c.747A>G	c.(745-747)caA>caG	p.Q249Q	CLEC4M_ENST00000248228.4_Silent_p.Q227Q|CLEC4M_ENST00000359059.5_Intron|CLEC4M_ENST00000597522.1_Intron|CLEC4M_ENST00000596363.1_Silent_p.Q221Q|CLEC4M_ENST00000596707.1_Intron|CLEC4M_ENST00000394122.2_Silent_p.Q237Q|CLEC4M_ENST00000357361.2_Silent_p.Q249Q|CLEC4M_ENST00000334806.5_Silent_p.Q198Q|CLEC4M_ENST00000595496.1_Intron	NM_001144909.1|NM_014257.4	NP_001138381.1|NP_055072.3	Q9H2X3	CLC4M_HUMAN	C-type lectin domain family 4, member M	249	7 X approximate tandem repeats.				cell-cell recognition|endocytosis|innate immune response|intracellular signal transduction|intracellular virion transport|leukocyte cell-cell adhesion|peptide antigen transport|viral genome replication|virion attachment to host cell surface receptor	cytoplasm|extracellular region|integral to plasma membrane	ICAM-3 receptor activity|mannose binding|metal ion binding|peptide antigen binding|virion binding			breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(10)|pancreas(1)|prostate(1)|skin(1)	26						AGCAGCAGCAAATCTATCAAG	0.512000													62	46					0	0	1	0	0
USP36	57602	broad.mit.edu	37	17	76831368	76831368	+	Missense_Mutation	SNP	G	G	A	rs151065333	byFrequency	TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr17:76831368G>A	ENST00000312010.6	-	4	793	c.469C>T	c.(469-471)Cgc>Tgc	p.R157C	USP36_ENST00000542802.2_Missense_Mutation_p.R157C|USP36_ENST00000589424.1_Missense_Mutation_p.R157C|USP36_ENST00000590546.2_Missense_Mutation_p.R157C	NM_025090.3	NP_079366.3	Q9P275	UBP36_HUMAN	ubiquitin specific peptidase 36	157					ubiquitin-dependent protein catabolic process	nucleolus	cysteine-type peptidase activity|ubiquitin thiolesterase activity			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(3)|large_intestine(5)|lung(12)|ovary(3)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	34			BRCA - Breast invasive adenocarcinoma(99;0.000842)|OV - Ovarian serous cystadenocarcinoma(97;0.151)			TCACAGCTGCGAGCATGCTCC	0.552000													4	36					0	0	1	0	0
CCDC64	92558	broad.mit.edu	37	12	120510313	120510313	+	Splice_Site	SNP	A	A	G			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr12:120510313A>G	ENST00000397558.2	+	6	1089		c.e6-1		CCDC64_ENST00000257583.4_Splice_Site|CCDC64_ENST00000446727.2_Intron	NM_207311.2	NP_997194.2	Q6ZP65	BICR1_HUMAN	coiled-coil domain containing 64						Golgi to secretory granule transport|neuron projection development	centrosome	dynactin binding|Rab GTPase binding			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|liver(2)|lung(4)|ovary(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	22	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)					TCTGTGGAACAGCTGAGACTG	0.502000													25	58					0	0	1	0	0
UNC13D	201294	broad.mit.edu	37	17	73825012	73825012	+	Missense_Mutation	SNP	C	C	A			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr17:73825012C>A	ENST00000207549.4	-	31	3386	c.3007G>T	c.(3007-3009)Gtg>Ttg	p.V1003L	UNC13D_ENST00000412096.2_Missense_Mutation_p.V1003L	NM_199242.2	NP_954712.1	Q70J99	UN13D_HUMAN	unc-13 homolog D (C. elegans)	1003	C2 2.				positive regulation of exocytosis|regulation of mast cell degranulation	exocytic vesicle|late endosome|lysosome|membrane|recycling endosome	protein binding			central_nervous_system(1)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(9)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	29			all cancers(21;2.11e-06)|Epithelial(20;2.32e-06)|BRCA - Breast invasive adenocarcinoma(9;0.000618)|LUSC - Lung squamous cell carcinoma(166;0.154)			TAGTCCAGCACGGTGAGCAGG	0.706000									Familial Hemophagocytic Lymphohistiocytosis				11	14					0.000978159	0.00102474	1	1	0
CSDE1	7812	broad.mit.edu	37	1	115268982	115268985	+	Frame_Shift_Del	DEL	TGTT	TGTT	-			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr1:115268982_115268985delTGTT	ENST00000438362.2	-	14	2003_2006	c.1625_1628delAACA	c.(1624-1629)agfs	p.KQ542fs	CSDE1_ENST00000369530.1_Frame_Shift_Del_p.KQ511fs|CSDE1_ENST00000339438.6_Frame_Shift_Del_p.KQ465fs|CSDE1_ENST00000261443.5_Frame_Shift_Del_p.KQ465fs|CSDE1_ENST00000534699.1_Frame_Shift_Del_p.KQ496fs|CSDE1_ENST00000530886.1_Frame_Shift_Del_p.KQ366fs|CSDE1_ENST00000358528.4_Frame_Shift_Del_p.KQ496fs	NM_001242891.1	NP_001229820.1	O75534	CSDE1_HUMAN	cold shock domain containing E1, RNA-binding	496	CSD 7.				male gonad development|regulation of transcription, DNA-dependent	cytoplasm	DNA binding|protein binding|RNA binding			NS(1)|breast(4)|endometrium(11)|kidney(2)|large_intestine(12)|lung(17)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)	51	all_epithelial(7;5.11e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;2.21e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		TCCAGGCCTCTGTTTGTCACTAAT	0.397													30	9	---	---	---	---					
TMEM184A	202915	broad.mit.edu	37	7	1586653	1586654	+	In_Frame_Ins	INS	-	-	GCC	rs112463195	by1000genomes	TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr7:1586653_1586654insGCC	ENST00000297477.5	-	9	1492_1493	c.1176_1177insGGC	c.(1174-1179)ggccgg>ggGGCccgg	p.392_393GR>GAR		NM_001097620.1	NP_001091089.1	Q6ZMB5	T184A_HUMAN	transmembrane protein 184A	392						integral to membrane				endometrium(1)|large_intestine(1)|lung(6)|upper_aerodigestive_tract(3)|urinary_tract(1)	12		Ovarian(82;0.0253)		UCEC - Uterine corpus endometrioid carcinoma (27;0.0178)|OV - Ovarian serous cystadenocarcinoma(56;5.88e-15)		CTCCCGCCGGAGCCGCCGCTGG	0.708													6	9	---	---	---	---					
RP11-536C10.7	0	broad.mit.edu	37	14	19408019	19408019	+	RNA	DEL	A	A	-			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr14:19408019delA	ENST00000548050.1	-	0	279					NR_046104.1																						CTGTGGAGCCAAAAAAAAAAT	0.393													3	6	---	---	---	---					
TAOK2	9344	broad.mit.edu	37	16	29989145	29989146	+	Frame_Shift_Del	DEL	CT	CT	-			TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr16:29989145_29989146delCT	ENST00000308893.4	+	2	1095_1096	c.52_53delCT	c.(52-54)cfs	p.L18fs	TAOK2_ENST00000279394.3_Frame_Shift_Del_p.L18fs|TAOK2_ENST00000543033.1_Frame_Shift_Del_p.L18fs	NM_001252043.1|NM_016151.3	NP_001238972.1|NP_057235.2	Q9UL54	TAOK2_HUMAN	TAO kinase 2	18					actin cytoskeleton organization|activation of MAPKK activity|apoptosis|cell migration|focal adhesion assembly|positive regulation of JNK cascade|protein targeting to membrane|regulation of cell growth|regulation of cell shape|response to stress	cytoplasmic vesicle membrane|cytoskeleton|dendrite|integral to membrane|nucleolus	ATP binding|protein serine/threonine kinase activity			breast(1)|endometrium(3)|large_intestine(5)|lung(8)|ovary(1)|prostate(3)|skin(1)	22						TGTGGCTGAGCTCTTCTTCAAG	0.609													44	38	---	---	---	---					
TBC1D3P2	0	broad.mit.edu	37	17	60347260	60347260	+	RNA	DEL	T	T	-	rs71816198		TCGA-RW-A681-01A-11D-A35D-08	TCGA-RW-A681-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5cecab91-4ebe-445b-a47f-90e9e970f7fb	b93b415b-3112-47cc-bd50-43798db2a87e	g.chr17:60347260delT	ENST00000581291.1	-	0	581																				breast(2)|kidney(1)|lung(2)	5						CTCTGAATGATTTTTTTTTTT	0.448													2	4	---	---	---	---					
