Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
F11R	50848	broad.mit.edu	37	1	160971131	160971131	+	Missense_Mutation	SNP	A	A	G			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr1:160971131A>G	ENST00000368026.6	-	2	351	c.77T>C	c.(76-78)tTg>tCg	p.L26S	F11R_ENST00000537746.1_Missense_Mutation_p.L26S|F11R_ENST00000289779.3_3'UTR	NM_016946.4	NP_058642.1	Q9Y624	JAM1_HUMAN	F11 receptor	26					blood coagulation|inflammatory response|interspecies interaction between organisms|leukocyte migration|tight junction assembly	integral to membrane|tight junction				breast(1)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(3)|ovary(2)	12	all_cancers(52;6.73e-18)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.00207)			AACACTGCCCAATGCCAGGGA	0.542000													3	39					0	0	1	0	0
FASTKD5	60493	broad.mit.edu	37	20	3128950	3128950	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr20:3128950C>T	ENST00000380266.3	-	2	1088	c.767G>A	c.(766-768)cGc>cAc	p.R256H	UBOX5_ENST00000348031.2_Intron|UBOX5_ENST00000217173.2_Intron|UBOX5-AS1_ENST00000446537.1_RNA	NM_021826.4	NP_068598.1	Q7L8L6	FAKD5_HUMAN	FAST kinase domains 5	256			R -> C (in dbSNP:rs3746700).		apoptosis|cellular respiration	mitochondrion	ATP binding|protein kinase activity			breast(2)|endometrium(2)|large_intestine(2)|lung(8)|prostate(2)|skin(1)|urinary_tract(2)	19						AGGTACTTTGCGGCCTAAGTA	0.393000													4	78					0	0	1	0	0
FBXO27	126433	broad.mit.edu	37	19	39522616	39522616	+	Silent	SNP	G	G	A			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr19:39522616G>A	ENST00000292853.4	-	2	371	c.252C>T	c.(250-252)caC>caT	p.H84H	FBXO27_ENST00000600828.1_Silent_p.H84H|FBXO27_ENST00000509137.2_Silent_p.H84H	NM_178820.3	NP_849142.1	Q8NI29	FBX27_HUMAN	F-box protein 27	84					protein catabolic process	SCF ubiquitin ligase complex	glycoprotein binding			cervix(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(5)|ovary(1)|urinary_tract(2)	17	all_cancers(60;3.79e-07)|all_lung(34;1.26e-07)|Lung NSC(34;1.46e-07)|all_epithelial(25;4.69e-07)|Ovarian(47;0.0454)		Lung(45;0.000419)|LUSC - Lung squamous cell carcinoma(53;0.000554)			TGCGGGCGAGGTGCAGCAGCG	0.736000													3	4					0	0	1	0	0
LILRB5	0	broad.mit.edu	37	19	54754843	54754843	+	Missense_Mutation	SNP	A	A	G			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr19:54754843A>G	ENST00000450632.1	-	13	1869	c.1792T>C	c.(1792-1794)Tcc>Ccc	p.S598P	LILRB5_ENST00000345866.6_Intron|LILRB5_ENST00000449561.2_Intron|LILRB5_ENST00000316219.5_Intron			O75023	LIRB5_HUMAN	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	423					cell surface receptor linked signaling pathway|defense response	integral to membrane	transmembrane receptor activity			NS(1)|breast(1)|endometrium(3)|kidney(5)|large_intestine(12)|lung(25)|ovary(1)|pancreas(1)|prostate(3)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	56	all_cancers(19;0.00681)|all_epithelial(19;0.00368)|all_lung(19;0.016)|Lung NSC(19;0.0296)|Ovarian(34;0.19)			GBM - Glioblastoma multiforme(193;0.105)		GGGGGTGGGGAGGCCTGGGGG	0.607000													5	19					0	0	1	0	0
LRRC43	254050	broad.mit.edu	37	12	122674895	122674895	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr12:122674895G>A	ENST00000339777.4	+	5	909	c.881G>A	c.(880-882)cGg>cAg	p.R294Q	LRRC43_ENST00000425921.1_Missense_Mutation_p.R109Q	NM_152759.4	NP_689972.3	Q8N309	LRC43_HUMAN	leucine rich repeat containing 43	294	LRRCT.									NS(1)|endometrium(1)|large_intestine(4)|lung(10)|skin(1)|upper_aerodigestive_tract(2)	19	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.000312)|Epithelial(86;0.000539)|BRCA - Breast invasive adenocarcinoma(302;0.225)		CATCTCTTCCGGGGGCTCAGC	0.667000													4	58					0	0	1	0	0
TUBB8P7	0	broad.mit.edu	37	16	90162513	90162513	+	RNA	SNP	T	T	C			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr16:90162513T>C	ENST00000564451.1	+	0	1866				TUBB8P7_ENST00000567960.1_RNA														p.N415N(2)									GCAACATGAATGACCTGGTGT	0.537000													5	107					0	0	1	0	0
POM121L9P	0	broad.mit.edu	37	22	24659734	24659734	+	RNA	SNP	T	T	C			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr22:24659734T>C	ENST00000414583.2	+	0	3259					NR_003714.1																						CTCTCTCCTGTGGGAGGGGGG	0.632000													3	12					0	0	1	0	0
MAGOH	4116	broad.mit.edu	37	1	53692717	53692717	+	Silent	SNP	C	C	T	rs75427086	byFrequency	TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr1:53692717C>T	ENST00000371470.3	-	5	602	c.441G>A	c.(439-441)taG>taA	p.*147*	MAGOH_ENST00000371466.4_Silent_p.*110*	NM_002370.3	NP_002361.1	P61326	MGN_HUMAN	mago-nashi homolog, proliferation-associated (Drosophila)	0					mRNA 3'-end processing|mRNA export from nucleus|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of translation|termination of RNA polymerase II transcription	catalytic step 2 spliceosome|cytosol|exon-exon junction complex|nuclear speck	protein binding|RNA binding			haematopoietic_and_lymphoid_tissue(1)|lung(4)|urinary_tract(1)	6						AATATTCAGTCTAGATTGGTT	0.368000													3	26					0	0	1	0	0
GABBR1	0	broad.mit.edu	37	6	29574694	29574694	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr6:29574694G>A	ENST00000377034.4	-	18	2532	c.2197C>T	c.(2197-2199)Cct>Tct	p.P733S	GABBR1_ENST00000377016.4_Missense_Mutation_p.P671S|GABBR1_ENST00000355973.3_Missense_Mutation_p.P616S|GABBR1_ENST00000377012.4_Missense_Mutation_p.P616S|GABBR1_ENST00000376977.3_3'UTR	NM_001470.2	NP_001461.1	Q9UBS5	GABR1_HUMAN	gamma-aminobutyric acid (GABA) B receptor, 1	733					gamma-aminobutyric acid signaling pathway|negative regulation of adenylate cyclase activity|synaptic transmission	cell junction|extracellular region|integral to plasma membrane|postsynaptic membrane	G-protein coupled receptor activity|GABA-B receptor activity			endometrium(3)|kidney(1)|large_intestine(13)|liver(1)|lung(16)|ovary(5)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	47					Baclofen(DB00181)|Progabide(DB00837)	CGGTGCAGAGGGTCCACGATC	0.587000													15	33					0	0	1	0	0
TUBA3E	112714	broad.mit.edu	37	2	130951512	130951512	+	Silent	SNP	C	C	T	rs146523442		TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr2:130951512C>T	ENST00000312988.7	-	4	1003	c.903G>A	c.(901-903)caG>caA	p.Q301Q		NM_207312.2	NP_997195.1	Q6PEY2	TBA3E_HUMAN	tubulin, alpha 3e	301					microtubule-based movement|protein polymerization	cytoplasm|microtubule	GTP binding|GTPase activity|structural molecule activity			endometrium(4)|kidney(7)|large_intestine(6)|lung(9)|skin(2)	28	Colorectal(110;0.1)					ACTTGACCATCTGATTGGCTG	0.602000													5	126					0	0	1	0	0
MAGOH	4116	broad.mit.edu	37	1	53692748	53692748	+	Missense_Mutation	SNP	A	A	G			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr1:53692748A>G	ENST00000371470.3	-	5	571	c.410T>C	c.(409-411)aTt>aCt	p.I137T	MAGOH_ENST00000371466.4_Missense_Mutation_p.I100T	NM_002370.3	NP_002361.1	P61326	MGN_HUMAN	mago-nashi homolog, proliferation-associated (Drosophila)	137					mRNA 3'-end processing|mRNA export from nucleus|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|regulation of translation|termination of RNA polymerase II transcription	catalytic step 2 spliceosome|cytosol|exon-exon junction complex|nuclear speck	protein binding|RNA binding	p.I137T(1)		haematopoietic_and_lymphoid_tissue(1)|lung(4)|urinary_tract(1)	6						GTGTAATCCAATAAGACTGAA	0.378000													3	29					0	0	1	0	0
RP11-377D9.3	0	broad.mit.edu	37	12	13174142	13174144	+	RNA	DEL	AAC	AAC	-	rs59907395		TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr12:13174142_13174144delAAC	ENST00000543321.1	+	0	1025																											ctgtctcaaaaacaacaacaaca	0.552													4	8	---	---	---	---					
SNX29P2	0	broad.mit.edu	37	16	29439785	29439786	+	RNA	INS	-	-	A			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr16:29439785_29439786insA	ENST00000398878.3	+	0	5991																											GTGGAACCATTAAAAAAAAACA	0.351													2	4	---	---	---	---					
FAM83D	81610	broad.mit.edu	37	20	37555202	37555202	+	Frame_Shift_Del	DEL	G	G	-			TCGA-RW-A68B-01A-11D-A35D-08	TCGA-RW-A68B-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4afc3d13-ad9f-4900-8507-b37de18d0347	dc696df8-0c64-4c3f-9044-7c0156062d78	g.chr20:37555202delG	ENST00000217429.4	+	1	248	c.207delG	c.(205-207)ctfs	p.L69fs		NM_030919.2	NP_112181.2	Q9H4H8	FA83D_HUMAN	family with sequence similarity 83, member D	39					cell division|mitosis	cytoplasm|spindle pole				endometrium(2)|kidney(2)|large_intestine(7)|lung(12)|ovary(4)|stomach(1)	28		Myeloproliferative disorder(115;0.00878)				TGGAGGAGCTGGTGGCGGGCG	0.736													2	4	---	---	---	---					
