Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
QRFPR	84109	broad.mit.edu	37	4	122250693	122250693	+	Missense_Mutation	SNP	G	G	C			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr4:122250693G>C	ENST00000394427.2	-	6	1483	c.1072C>G	c.(1072-1074)Cca>Gca	p.P358A	QRFPR_ENST00000334383.5_3'UTR	NM_198179.2	NP_937822.2	Q96P65	QRFPR_HUMAN	pyroglutamylated RFamide peptide receptor	358						plasma membrane	neuropeptide Y receptor activity			endometrium(1)|kidney(2)|large_intestine(9)|lung(10)|prostate(2)|skin(3)|stomach(1)	28						CTTTGTGCTGGAGAGAAGGTT	0.368000													6	140					0	0	1	0	0
MACROD1	28992	broad.mit.edu	37	11	63767229	63767229	+	Missense_Mutation	SNP	A	A	G			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr11:63767229A>G	ENST00000255681.6	-	6	737	c.671T>C	c.(670-672)aTc>aCc	p.I224T	OTUB1_ENST00000535715.1_Intron	NM_014067.3	NP_054786.2	Q9BQ69	MACD1_HUMAN	MACRO domain containing 1	224	Macro.									breast(1)|large_intestine(3)|lung(6)|skin(1)	11						CACTGTGTGGATGACGTCTAC	0.701000													3	3					0	0	1	0	0
RNF149	284996	broad.mit.edu	37	2	101893717	101893717	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr2:101893717C>T	ENST00000295317.3	-	7	1293	c.1186G>A	c.(1186-1188)Gga>Aga	p.G396R		NM_173647.3	NP_775918.2	Q8NC42	RN149_HUMAN	ring finger protein 149	396						integral to membrane	ligase activity|zinc ion binding			breast(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(1)|lung(3)|ovary(1)|prostate(1)	12						ATGGGTCCTCCATGCCGAGAG	0.458000													15	29					0	0	1	0	0
SLC35C1	55343	broad.mit.edu	37	11	45827751	45827751	+	Silent	SNP	C	C	G			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr11:45827751C>G	ENST00000314134.3	+	1	1795	c.399C>G	c.(397-399)ctC>ctG	p.L133L	SLC35C1_ENST00000442528.2_Silent_p.L120L|SLC35C1_ENST00000456334.1_Silent_p.L120L	NM_018389.4	NP_060859.4	Q96A29	FUCT1_HUMAN	solute carrier family 35 (GDP-fucose transporter), member C1	133						Golgi membrane|integral to membrane	GDP-fucose transmembrane transporter activity			endometrium(3)|kidney(1)|lung(4)|ovary(1)|upper_aerodigestive_tract(1)	10				GBM - Glioblastoma multiforme(35;0.227)		TCAATAACCTCTGCCTCAAGT	0.607000													28	10					0	0	1	0	0
CCR8	1237	broad.mit.edu	37	3	39374010	39374010	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr3:39374010G>A	ENST00000326306.4	+	2	326	c.188G>A	c.(187-189)tGc>tAc	p.C63Y	CCR8_ENST00000545843.1_Intron|CCR8_ENST00000414803.1_Intron	NM_005201.3	NP_005192.1	P51685	CCR8_HUMAN	chemokine (C-C motif) receptor 8	63					cell adhesion|chemotaxis|elevation of cytosolic calcium ion concentration|immune response	integral to plasma membrane	coreceptor activity			NS(3)|breast(1)|endometrium(3)|large_intestine(5)|lung(7)|ovary(1)|skin(1)	21				KIRC - Kidney renal clear cell carcinoma(284;0.0504)|Kidney(284;0.0635)		CTTGTGGTCTGCAAGAAGCTG	0.478000													4	161					0	0	1	0	0
WASH3P	0	broad.mit.edu	37	15	102516511	102516511	+	RNA	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr15:102516511C>T	ENST00000557932.1	+	0	1459																				central_nervous_system(1)|endometrium(6)|kidney(11)|prostate(5)|stomach(1)|urinary_tract(1)	25						AGACTTGGGCCGTTGCTCTGA	0.627000													3	45					0	0	1	0	0
NUCKS1	64710	broad.mit.edu	37	1	205687522	205687522	+	Silent	SNP	T	T	C			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr1:205687522T>C	ENST00000367142.4	-	7	920	c.618A>G	c.(616-618)aaA>aaG	p.K206K		NM_022731.4	NP_073568.2	Q9H1E3	NUCKS_HUMAN	nuclear casein kinase and cyclin-dependent kinase substrate 1	206	Lys-rich.					nucleus				endometrium(4)|large_intestine(1)|lung(9)	14	Breast(84;0.07)		BRCA - Breast invasive adenocarcinoma(75;0.0194)			CATCTTCTTCTTTGGGAGAAG	0.493000													93	155					0	0	1	0	0
LL22NC03-80A10.6	0	broad.mit.edu	37	22	22664141	22664141	+	RNA	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr22:22664141G>A	ENST00000426066.1	+	0	664					NR_027293.1																						AAATTTGAAGGTGCTGTGATT	0.448000													4	88					0	0	1	0	0
TMEM2	23670	broad.mit.edu	37	9	74360015	74360015	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr9:74360015G>A	ENST00000377044.4	-	4	1492	c.953C>T	c.(952-954)gCc>gTc	p.A318V	TMEM2_ENST00000377066.5_Missense_Mutation_p.A318V	NM_001135820.1|NM_013390.2	NP_001129292.1|NP_037522.1	Q9UHN6	TMEM2_HUMAN	transmembrane protein 2	318						integral to membrane				central_nervous_system(1)|endometrium(6)|kidney(3)|large_intestine(15)|liver(1)|lung(19)|ovary(2)|prostate(5)|skin(1)|stomach(1)|urinary_tract(2)	56		all_epithelial(88;4.56e-14)|Myeloproliferative disorder(762;0.0255)		GBM - Glioblastoma multiforme(74;7.45e-21)|OV - Ovarian serous cystadenocarcinoma(323;1.02e-16)		ACTTTTAGCGGCTGAATCCCC	0.507000													4	150					0	0	1	0	0
TPTE2P6	0	broad.mit.edu	37	13	25168471	25168471	+	RNA	SNP	C	C	T	rs61946941	by1000genomes	TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr13:25168471C>T	ENST00000453498.1	+	0	1143																											CATCTCTGTACGATGATGTGA	0.358000													4	60					0	0	1	0	0
FZD8	8325	broad.mit.edu	37	10	35928890	35928890	+	Missense_Mutation	SNP	C	C	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr10:35928890C>A	ENST00000374694.1	-	1	1472	c.1468G>T	c.(1468-1470)Gtc>Ttc	p.V490F		NM_031866.2	NP_114072.1	Q9H461	FZD8_HUMAN	frizzled family receptor 8	490					axonogenesis|brain development|canonical Wnt receptor signaling pathway|embryo development|gonad development|T cell differentiation in thymus|vasculature development	cell projection|Golgi apparatus|integral to membrane|plasma membrane	G-protein coupled receptor activity|PDZ domain binding|Wnt receptor activity|Wnt-protein binding			central_nervous_system(1)|endometrium(3)|large_intestine(2)|lung(3)|prostate(1)|urinary_tract(1)	11						AGGTAGATGACCAGCGGCGCC	0.662000													3	24					0.115264	0.115264	1	1	0
WASF3	10810	broad.mit.edu	37	13	27255299	27255299	+	Silent	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr13:27255299C>T	ENST00000361042.4	+	8	1041	c.816C>T	c.(814-816)caC>caT	p.H272H	WASF3_ENST00000335327.5_Silent_p.H275H			Q9UPY6	WASF3_HUMAN	WAS protein family, member 3	275					actin filament polymerization	cytoplasm|cytoskeleton	actin binding			breast(2)|endometrium(3)|kidney(2)|large_intestine(4)|lung(6)|pancreas(1)|prostate(2)|skin(2)	22	Colorectal(5;0.000247)	Lung SC(185;0.0156)|Breast(139;0.147)		all cancers(112;0.0114)|Epithelial(112;0.046)|OV - Ovarian serous cystadenocarcinoma(117;0.0547)|Lung(94;0.105)|LUSC - Lung squamous cell carcinoma(192;0.155)		TGCCACCACACGGGCCTGCAA	0.652000													4	135					0	0	1	0	0
RAB35	11021	broad.mit.edu	37	12	120536942	120536942	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr12:120536942G>A	ENST00000229340.5	-	4	432	c.244C>T	c.(244-246)Cac>Tac	p.H82Y	RAB35_ENST00000543364.1_5'UTR|RAB35_ENST00000534951.1_Missense_Mutation_p.H82Y	NM_001167606.1|NM_006861.6	NP_001161078.1|NP_006852.1	Q15286	RAB35_HUMAN	RAB35, member RAS oncogene family	82					cytokinesis|endosome transport|protein transport|small GTPase mediated signal transduction	cell projection membrane|clathrin-coated endocytic vesicle|coated pit|endosome|intercellular bridge|melanosome	GTP binding|GTPase activity|phosphatidylinositol-4,5-bisphosphate binding			endometrium(1)|ovary(1)	2	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)			BRCA - Breast invasive adenocarcinoma(302;0.248)		ATGACCCCGTGGGTCCCCCGA	0.597000													32	33					0	0	1	0	0
KIAA0319	9856	broad.mit.edu	37	6	24596193	24596193	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr6:24596193G>A	ENST00000535378.1	-	4	1324	c.682C>T	c.(682-684)Ccc>Tcc	p.P228S	KIAA0319_ENST00000543707.1_Missense_Mutation_p.P237S|KIAA0319_ENST00000378214.3_Missense_Mutation_p.P237S|KIAA0319_ENST00000537886.1_Missense_Mutation_p.P237S|KIAA0319_ENST00000430948.2_Missense_Mutation_p.P192S	NM_001168374.1	NP_001161846.1	Q5VV43	K0319_HUMAN	KIAA0319	237					negative regulation of dendrite development|neuron migration	early endosome membrane|integral to membrane|plasma membrane	protein binding			breast(3)|endometrium(6)|kidney(3)|large_intestine(11)|lung(19)|ovary(1)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)	53						GTCGGCAAGGGAAGCAACACA	0.542000													15	64					0	0	1	0	0
ZMYND10	51364	broad.mit.edu	37	3	50379081	50379081	+	Missense_Mutation	SNP	G	G	A	rs150467144	byFrequency	TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr3:50379081G>A	ENST00000231749.3	-	11	2443	c.1171C>T	c.(1171-1173)Cgg>Tgg	p.R391W	ZMYND10-AS1_ENST00000440013.1_RNA|ZMYND10_ENST00000360165.3_Missense_Mutation_p.R386W|ZMYND10_ENST00000490675.1_5'UTR	NM_015896.2	NP_056980.2	O75800	ZMY10_HUMAN	zinc finger, MYND-type containing 10	391						cytoplasm	protein binding|zinc ion binding			endometrium(3)|kidney(2)|large_intestine(1)|lung(5)|ovary(1)|urinary_tract(2)	14				BRCA - Breast invasive adenocarcinoma(193;0.000272)|KIRC - Kidney renal clear cell carcinoma(197;0.00544)|Kidney(197;0.00607)		CAGCGGGGCCGCTCTGGAGCC	0.602000										TSP Lung(30;0.18)			4	59					0	0	1	0	0
BDP1	55814	broad.mit.edu	37	5	70757730	70757730	+	Silent	SNP	T	T	C			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr5:70757730T>C	ENST00000358731.4	+	3	839	c.576T>C	c.(574-576)taT>taC	p.Y192Y	BDP1_ENST00000380675.2_5'UTR	NM_018429.2	NP_060899.2	A6H8Y1	BDP1_HUMAN	B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB	192	Interaction with ZBTB43.				regulation of transcription, DNA-dependent|transcription from RNA polymerase III promoter	nucleoplasm	DNA binding			NS(2)|breast(3)|cervix(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(13)|lung(34)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	72		Lung NSC(167;0.000422)|Prostate(74;0.00815)|Ovarian(174;0.0176)|Breast(144;0.198)		OV - Ovarian serous cystadenocarcinoma(47;5.28e-56)|Epithelial(20;2.31e-50)		TCATATATTATCTACCAGATA	0.308000													8	148					0	0	1	0	0
MLXIP	22877	broad.mit.edu	37	12	122611891	122611891	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr12:122611891C>T	ENST00000319080.6	+	2	634	c.502C>T	c.(502-504)Cgg>Tgg	p.R168W				Q9HAP2	MLXIP_HUMAN	MLX interacting protein	168	Required for cytoplasmic localization.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrial outer membrane|nucleus	DNA binding			NS(1)|endometrium(4)|kidney(1)|large_intestine(4)|lung(7)|ovary(3)	20	all_neural(191;0.0837)|Medulloblastoma(191;0.163)	Lung NSC(355;0.0659)		OV - Ovarian serous cystadenocarcinoma(86;0.000599)|Epithelial(86;0.00102)|BRCA - Breast invasive adenocarcinoma(302;0.233)		TGCCATCTGGCGGGCCTGGTA	0.587000													12	15					0	0	1	0	0
DCC	1630	broad.mit.edu	37	18	50734115	50734115	+	Nonsense_Mutation	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr18:50734115C>T	ENST00000442544.2	+	11	2405	c.1789C>T	c.(1789-1791)Cga>Tga	p.R597*	DCC_ENST00000412726.1_Nonsense_Mutation_p.R445*|DCC_ENST00000581580.1_Nonsense_Mutation_p.R252*	NM_005215.3	NP_005206.2	P43146	DCC_HUMAN	deleted in colorectal carcinoma	597	Fibronectin type-III 2.				apoptosis|induction of apoptosis|negative regulation of collateral sprouting|negative regulation of dendrite development	cytosol|integral to membrane				NS(3)|breast(2)|central_nervous_system(1)|cervix(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(23)|liver(1)|lung(56)|ovary(7)|pancreas(3)|prostate(2)|skin(16)|stomach(2)|upper_aerodigestive_tract(4)|urinary_tract(6)	148		all_cancers(7;0.11)|all_epithelial(6;0.00126)		Colorectal(16;0.0251)|COAD - Colon adenocarcinoma(17;0.0942)		ATATAGTCTTCGATTCTTAGC	0.373000													5	211					0	0	1	0	0
MTHFD1L	25902	broad.mit.edu	37	6	151336057	151336057	+	Silent	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr6:151336057G>A	ENST00000367321.3	+	23	2623	c.2349G>A	c.(2347-2349)aaG>aaA	p.K783K		NM_001242767.1|NM_001242768.1|NM_015440.4	NP_001229696.1|NP_001229697.1|NP_056255.2	Q6UB35	C1TM_HUMAN	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	783	Formyltetrahydrofolate synthetase.				folic acid-containing compound biosynthetic process|formate metabolic process|one-carbon metabolic process|tetrahydrofolate metabolic process	mitochondrion	ATP binding|formate-tetrahydrofolate ligase activity|protein homodimerization activity			central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(12)|lung(8)|ovary(3)|prostate(1)|upper_aerodigestive_tract(2)	29		Ovarian(120;0.128)		OV - Ovarian serous cystadenocarcinoma(155;8.7e-12)		ACCTCCAGAAGCAAATTCAGA	0.478000											OREG0017732	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	4	73					0	0	1	0	0
PAK3	5063	broad.mit.edu	37	X	110439691	110439691	+	Silent	SNP	C	C	G			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chrX:110439691C>G	ENST00000519681.1	+	17	1735	c.1293C>G	c.(1291-1293)gcC>gcG	p.A431A	PAK3_ENST00000446737.1_Silent_p.A410A|PAK3_ENST00000425146.1_Silent_p.A410A|PAK3_ENST00000262836.4_Silent_p.A425A|PAK3_ENST00000372007.4_Silent_p.A410A|PAK3_ENST00000372010.1_Silent_p.A425A|PAK3_ENST00000360648.4_Silent_p.A446A|PAK3_ENST00000518291.1_Silent_p.A446A|PAK3_ENST00000417227.1_Silent_p.A431A			O75914	PAK3_HUMAN	p21 protein (Cdc42/Rac)-activated kinase 3	425	Protein kinase.				multicellular organismal development		ATP binding|metal ion binding|protein serine/threonine kinase activity|SH3 domain binding			breast(1)|cervix(1)|endometrium(6)|kidney(1)|large_intestine(7)|lung(15)|ovary(3)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(4)	41						GGTTCTGTGCCCAGATCACTC	0.433000										TSP Lung(19;0.15)			13	115					0	0	1	0	0
NCOA3	8202	broad.mit.edu	37	20	46279860	46279860	+	Silent	SNP	G	G	A	rs151060280	byFrequency	TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr20:46279860G>A	ENST00000372004.3	+	20	3990	c.3774G>A	c.(3772-3774)caG>caA	p.Q1258Q	NCOA3_ENST00000371997.3_Silent_p.Q1253Q|NCOA3_ENST00000341724.6_Silent_p.Q1188Q|NCOA3_ENST00000371998.3_Silent_p.Q1262Q	NM_001174087.1|NM_001174088.1|NM_006534.3|NM_181659.2	NP_001167558.1|NP_001167559.1|NP_006525.2|NP_858045.1	Q9Y6Q9	NCOA3_HUMAN	nuclear receptor coactivator 3	1262	Acetyltransferase.|Poly-Gln.				androgen receptor signaling pathway|cellular lipid metabolic process|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nucleoplasm	androgen receptor binding|histone acetyltransferase activity|ligand-dependent nuclear receptor binding|protein N-terminus binding|signal transducer activity|thyroid hormone receptor binding	p.Q1262Q(1)		breast(3)|endometrium(3)|kidney(4)|large_intestine(12)|lung(19)|ovary(4)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	52						agcagcagcagcagcaacagc	0.567000													6	57					0	0	1	0	0
RSF1	51773	broad.mit.edu	37	11	77386295	77386295	+	Silent	SNP	T	T	C			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr11:77386295T>C	ENST00000308488.6	-	14	3650	c.3348A>G	c.(3346-3348)caA>caG	p.Q1116Q	RSF1_ENST00000480887.1_Silent_p.Q864Q|RSF1_ENST00000360355.2_Silent_p.Q1085Q			Q96T23	RSF1_HUMAN	remodeling and spacing factor 1	1116					CenH3-containing nucleosome assembly at centromere|negative regulation of DNA binding|negative regulation of transcription, DNA-dependent|nucleosome positioning|positive regulation of transcription, DNA-dependent|positive regulation of viral transcription|transcription initiation, DNA-dependent	RSF complex	histone binding|protein binding|zinc ion binding			breast(3)|central_nervous_system(2)|endometrium(3)|kidney(4)|large_intestine(9)|lung(14)|ovary(2)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	43	all_cancers(14;1.54e-17)|all_epithelial(13;4.06e-20)|Ovarian(111;0.152)		Epithelial(5;3e-50)|all cancers(3;6.37e-47)|BRCA - Breast invasive adenocarcinoma(5;9.82e-31)			CAAACTCATCTTGAGATCTGT	0.398000													16	8					0	0	1	0	0
ECHDC2	55268	broad.mit.edu	37	1	53377454	53377454	+	Missense_Mutation	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr1:53377454C>T	ENST00000371522.4	-	2	223	c.130G>A	c.(130-132)Gag>Aag	p.E44K	ECHDC2_ENST00000541281.1_5'UTR|ECHDC2_ENST00000536120.1_5'UTR|ECHDC2_ENST00000358358.5_Missense_Mutation_p.E44K|ECHDC2_ENST00000480312.2_5'UTR	NM_001198961.1	NP_001185890.1	Q86YB7	ECHD2_HUMAN	enoyl CoA hydratase domain containing 2	44					fatty acid metabolic process	mitochondrion	lyase activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(3)|prostate(1)|urinary_tract(1)	12						ATCAGAATCTCAGTGATCCCT	0.617000													22	15					0	0	1	0	0
SEMA3E	9723	broad.mit.edu	37	7	83029537	83029537	+	Silent	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr7:83029537G>A	ENST00000307792.3	-	11	1640	c.1173C>T	c.(1171-1173)taC>taT	p.Y391Y	SEMA3E_ENST00000427262.1_Silent_p.Y331Y	NM_012431.2	NP_036563.1	O15041	SEM3E_HUMAN	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	391	Sema.				axon guidance	extracellular space|membrane	receptor activity			breast(1)|endometrium(3)|kidney(4)|large_intestine(12)|liver(1)|lung(19)|ovary(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(3)	51		Medulloblastoma(109;0.109)				TGGTGGTTCCGTATCTCCCTC	0.388000													4	105					0	0	1	0	0
C3orf20	84077	broad.mit.edu	37	3	14745942	14745942	+	Missense_Mutation	SNP	G	G	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr3:14745942G>A	ENST00000253697.3	+	7	1429	c.977G>A	c.(976-978)cGc>cAc	p.R326H	C3orf20_ENST00000495387.1_3'UTR|C3orf20_ENST00000412910.1_Missense_Mutation_p.R204H|C3orf20_ENST00000435614.1_Missense_Mutation_p.R204H	NM_032137.4	NP_115513.4	Q8ND61	CC020_HUMAN	chromosome 3 open reading frame 20	326						cytoplasm|integral to membrane		p.R326H(1)		NS(1)|breast(1)|central_nervous_system(1)|endometrium(5)|kidney(2)|large_intestine(13)|lung(11)|ovary(4)|skin(2)	40						ATGTTGGCCCGCAAAGGAGAC	0.517000													4	122					0	0	1	0	0
RGAG1	57529	broad.mit.edu	37	X	109695456	109695456	+	Silent	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chrX:109695456C>T	ENST00000465301.2	+	3	1857	c.1611C>T	c.(1609-1611)tcC>tcT	p.S537S	RGAG1_ENST00000540313.1_Silent_p.S537S	NM_020769.2	NP_065820.1	Q8NET4	RGAG1_HUMAN	retrotransposon gag domain containing 1	537										NS(1)|autonomic_ganglia(1)|breast(2)|cervix(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(15)|liver(1)|lung(29)|ovary(1)|prostate(5)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(2)	73						GATCAATGTCCATGCTGCAAA	0.502000													84	126					0	0	1	0	0
NUP205	23165	broad.mit.edu	37	7	135323404	135323404	+	Missense_Mutation	SNP	A	A	G			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr7:135323404A>G	ENST00000285968.6	+	38	5391	c.5365A>G	c.(5365-5367)Aca>Gca	p.T1789A		NM_015135.2	NP_055950.1	Q92621	NU205_HUMAN	nucleoporin 205kDa	1789					carbohydrate metabolic process|glucose transport|mRNA transport|protein import into nucleus, docking|regulation of glucose transport|transmembrane transport|viral reproduction	nuclear pore	protein binding			breast(4)|central_nervous_system(2)|endometrium(9)|kidney(7)|large_intestine(17)|liver(4)|lung(36)|ovary(5)|prostate(1)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	93						CCTTTCAGAAACAGTTAATAG	0.438000													5	161					0	0	1	0	0
IQSEC2	23096	broad.mit.edu	37	X	53268384	53268384	+	Missense_Mutation	SNP	C	C	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chrX:53268384C>A	ENST00000396435.3	-	11	3308	c.3108G>T	c.(3106-3108)caG>caT	p.Q1036H	IQSEC2_ENST00000375365.2_Missense_Mutation_p.Q831H|IQSEC2_ENST00000375368.5_Missense_Mutation_p.Q1026H	NM_001111125.2	NP_001104595.1	Q5JU85	IQEC2_HUMAN	IQ motif and Sec7 domain 2	1026	PH.				regulation of ARF protein signal transduction	cytoplasm	ARF guanyl-nucleotide exchange factor activity			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(4)|lung(10)|ovary(4)|skin(1)	29						CACATGAATTCTGGAAGAGCT	0.502000											OREG0019800	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	4	53					5.9392e-07	6.28856e-07	1	1	0
SLC38A4	55089	broad.mit.edu	37	12	47172479	47172479	+	Silent	SNP	C	C	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr12:47172479C>T	ENST00000447411.1	-	10	1004	c.798G>A	c.(796-798)acG>acA	p.T266T	SLC38A4_ENST00000266579.4_Silent_p.T266T	NM_001143824.1	NP_001137296.1	Q969I6	S38A4_HUMAN	solute carrier family 38, member 4	266					cellular nitrogen compound metabolic process|sodium ion transport	integral to membrane|plasma membrane	amino acid transmembrane transporter activity|symporter activity			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(2)|large_intestine(4)|lung(6)|ovary(3)|skin(1)	21	Lung SC(27;0.192)|Renal(347;0.236)					GCATTGGAAGCGTGTTGTTGA	0.428000													35	46					0	0	1	0	0
COL4A5	1287	broad.mit.edu	37	X	107930801	107930801	+	Missense_Mutation	SNP	C	C	A			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chrX:107930801C>A	ENST00000328300.6	+	49	4649	c.4405C>A	c.(4405-4407)Ctt>Att	p.L1469I	COL4A5_ENST00000361603.2_Missense_Mutation_p.L1463I	NM_033380.2	NP_203699.1	P29400	CO4A5_HUMAN	collagen, type IV, alpha 5	1463	Collagen IV NC1.				axon guidance	collagen type IV	extracellular matrix structural constituent|protein binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(25)|lung(32)|ovary(4)|prostate(2)|skin(8)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	99						ACATGGATTTCTTATTACACG	0.517000									Alport syndrome with Diffuse Leiomyomatosis				4	140					0.00909568	0.00935556	1	1	0
STXBP3	6814	broad.mit.edu	37	1	109338934	109338934	+	Frame_Shift_Del	DEL	A	A	-			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr1:109338934delA	ENST00000370008.3	+	14	1239	c.1189delA	c.(1189-1191)aafs	p.K397fs		NM_007269.2	NP_009200.2	O00186	STXB3_HUMAN	syntaxin binding protein 3	397					negative regulation of calcium ion-dependent exocytosis|neutrophil degranulation|platelet aggregation|protein transport|vesicle docking involved in exocytosis	cytosol|nucleus|platelet alpha granule|specific granule|tertiary granule	syntaxin-2 binding			breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(3)|lung(2)|ovary(3)|urinary_tract(1)	13		all_epithelial(167;0.000154)|all_lung(203;0.00026)|Lung NSC(277;0.000508)		Colorectal(144;0.0386)|Lung(183;0.104)|COAD - Colon adenocarcinoma(174;0.137)|Epithelial(280;0.231)		TCTACTCAACAAAAATCATGA	0.308													19	32	---	---	---	---					
CDS1	1040	broad.mit.edu	37	4	85556474	85556475	+	Frame_Shift_Ins	INS	-	-	T			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr4:85556474_85556475insT	ENST00000295887.5	+	8	1203_1204	c.780_781insT	c.(778-783)ggttttfs	p.GF260fs		NM_001263.3	NP_001254.2	Q92903	CDS1_HUMAN	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1	260					signal transduction|visual perception	endoplasmic reticulum membrane|integral to membrane	diacylglycerol cholinephosphotransferase activity|phosphatidate cytidylyltransferase activity	p.G260G(1)		breast(1)|endometrium(3)|kidney(1)|large_intestine(7)|liver(2)|lung(5)|ovary(1)	20		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.00101)		ACCTTTTTGGATTTTTTTTTGG	0.307													9	107	---	---	---	---					
DTX2	113878	broad.mit.edu	37	7	76112249	76112249	+	Frame_Shift_Del	DEL	A	A	-	rs147779783	byFrequency	TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr7:76112249delA	ENST00000324432.5	+	5	1203	c.693delA	c.(691-693)ccfs	p.P231fs	DTX2_ENST00000430490.2_Frame_Shift_Del_p.P231fs|DTX2_ENST00000446600.1_Frame_Shift_Del_p.P140fs|DTX2_ENST00000413936.2_Frame_Shift_Del_p.P231fs|DTX2_ENST00000446820.2_Frame_Shift_Del_p.P231fs|DTX2_ENST00000307569.8_Frame_Shift_Del_p.P231fs	NM_020892.2	NP_065943.2	Q86UW9	DTX2_HUMAN	deltex homolog 2 (Drosophila)	231					Notch signaling pathway	cytoplasm|nucleus	protein binding|zinc ion binding			NS(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(14)|ovary(1)|skin(1)|stomach(2)	27						AGCACCCCCCACACAGGACCG	0.657													8	413	---	---	---	---					
SFRP1	6422	broad.mit.edu	37	8	41166638	41166640	+	In_Frame_Del	DEL	GCT	GCT	-	rs3055861		TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr8:41166638_41166640delGCT	ENST00000220772.3	-	1	376_378	c.39_41delAGC	c.(37-42)gcc>gc	p.AA13del		NM_003012.4	NP_003003.3	Q8N474	SFRP1_HUMAN	secreted frizzled-related protein 1	13					brain development|canonical Wnt receptor signaling pathway|cellular response to BMP stimulus|cellular response to estradiol stimulus|cellular response to fibroblast growth factor stimulus|cellular response to heparin|cellular response to hypoxia|cellular response to interleukin-1|cellular response to prostaglandin E stimulus|cellular response to starvation|cellular response to transforming growth factor beta stimulus|cellular response to tumor necrosis factor|cellular response to vitamin D|DNA fragmentation involved in apoptotic nuclear change|dorsal/ventral axis specification|hemopoietic progenitor cell differentiation|hemopoietic stem cell differentiation|menstrual cycle phase|negative regulation of androgen receptor signaling pathway|negative regulation of B cell differentiation|negative regulation of bone remodeling|negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation|negative regulation of cell growth|negative regulation of cell migration|negative regulation of cysteine-type endopeptidase activity|negative regulation of epithelial cell proliferation|negative regulation of epithelial to mesenchymal transition|negative regulation of fibroblast apoptosis|negative regulation of fibroblast proliferation|negative regulation of insulin secretion|negative regulation of ossification|negative regulation of osteoblast proliferation|negative regulation of peptidyl-tyrosine phosphorylation|negative regulation of transcription, DNA-dependent|negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification|osteoblast differentiation|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of cell growth|positive regulation of epithelial cell proliferation|positive regulation of fat cell differentiation|positive regulation of fibroblast apoptosis|positive regulation of focal adhesion assembly|positive regulation of non-canonical Wnt receptor signaling pathway|positive regulation of Rac GTPase activity|positive regulation of smoothened signaling pathway|positive regulation of stress fiber assembly|positive regulation of transcription, DNA-dependent|regulation of angiogenesis|regulation of cell cycle process|response to drug|response to organic cyclic compound|vasculature development	cell surface|cytosol|extracellular space|plasma membrane|proteinaceous extracellular matrix	cysteine-type endopeptidase activity|drug binding|frizzled binding|heparin binding|identical protein binding|PDZ domain binding|Wnt receptor activity|Wnt-protein binding			breast(1)|central_nervous_system(1)|large_intestine(2)|liver(1)|lung(1)|skin(1)	7	Breast(1;9.19e-13)|Ovarian(28;0.00769)|Colorectal(14;0.0305)|Lung SC(25;0.211)	all_lung(54;0.0034)|Lung NSC(58;0.0134)|Hepatocellular(245;0.023)|Esophageal squamous(32;0.0559)	BRCA - Breast invasive adenocarcinoma(1;1.11e-10)|LUSC - Lung squamous cell carcinoma(45;0.00894)|COAD - Colon adenocarcinoma(11;0.0174)			CACGCCCAGGGCTGCCCCGCGGC	0.764													3	4	---	---	---	---					
UBE2W	55284	broad.mit.edu	37	8	74737421	74737421	+	Frame_Shift_Del	DEL	T	T	-			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr8:74737421delT	ENST00000517608.1	-	3	258	c.258delA	c.(256-258)ctfs	p.L86fs	UBE2W_ENST00000602593.1_Frame_Shift_Del_p.L57fs|UBE2W_ENST00000453587.2_Frame_Shift_Del_p.L57fs|UBE2W_ENST00000602969.1_Frame_Shift_Del_p.L68fs|RP11-463D19.2_ENST00000358757.5_Frame_Shift_Del_p.L57fs|UBE2W_ENST00000419880.3_Frame_Shift_Del_p.L97fs			Q96B02	UBE2W_HUMAN	ubiquitin-conjugating enzyme E2W (putative)	57					protein K11-linked ubiquitination|protein monoubiquitination		ATP binding|protein binding|ubiquitin-protein ligase activity			kidney(1)|lung(1)	2	Breast(64;0.0311)		Epithelial(68;0.0235)|all cancers(69;0.0687)|BRCA - Breast invasive adenocarcinoma(89;0.069)			TAAATTTAAATAGAAGTTGAA	0.313													2	4	---	---	---	---					
LRRC27	80313	broad.mit.edu	37	10	134169317	134169317	+	Frame_Shift_Del	DEL	G	G	-			TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr10:134169317delG	ENST00000368610.3	+	7	911	c.911delG	c.(910-912)tgfs	p.W304fs	LRRC27_ENST00000432555.2_Frame_Shift_Del_p.W239fs|LRRC27_ENST00000392638.2_3'UTR|LRRC27_ENST00000368614.3_Frame_Shift_Del_p.W366fs|LRRC27_ENST00000475747.1_3'UTR|LRRC27_ENST00000368613.4_Frame_Shift_Del_p.W366fs|LRRC27_ENST00000368612.1_Frame_Shift_Del_p.W304fs			Q9C0I9	LRC27_HUMAN	leucine rich repeat containing 27	366										breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(8)|ovary(1)|pancreas(1)	18		all_cancers(35;6.28e-08)|all_epithelial(44;6.75e-06)|Lung NSC(174;0.0108)|all_lung(145;0.0173)|all_neural(114;0.0726)|Glioma(114;0.172)|Melanoma(40;0.175)|Colorectal(31;0.19)		OV - Ovarian serous cystadenocarcinoma(35;9.12e-05)|Epithelial(32;0.000116)|all cancers(32;0.000145)|BRCA - Breast invasive adenocarcinoma(275;0.218)		CTGCAGGAGTGGAGAGAGCGA	0.572													2	4	---	---	---	---					
ZNF559	84527	broad.mit.edu	37	19	9452027	9452028	+	Frame_Shift_Del	DEL	CT	CT	-	rs55837495		TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chr19:9452027_9452028delCT	ENST00000592504.1	+	6	665_666	c.410_411delCT	c.(409-411)afs	p.T137fs	ZNF177_ENST00000541595.2_Intron|ZNF177_ENST00000446085.4_Intron|ZNF559_ENST00000538743.1_Intron|ZNF559_ENST00000393883.2_Intron|ZNF559_ENST00000317221.7_Intron|ZNF177_ENST00000602738.1_Intron|ZNF559_ENST00000603380.1_Intron|ZNF177_ENST00000602856.1_Intron|ZNF559_ENST00000587557.1_Intron|ZNF559_ENST00000586255.1_Intron|ZNF177_ENST00000605471.1_Intron|ZNF559_ENST00000585352.1_Intron|ZNF559_ENST00000592896.1_Intron			Q9BR84	ZN559_HUMAN	zinc finger protein 559	0					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(2)|large_intestine(7)|lung(15)|ovary(1)|urinary_tract(1)	26						TTGACAAACACTCTAAACATCC	0.347													4	2	---	---	---	---					
NUDT11	0	broad.mit.edu	37	X	51239296	51239309	+	Translation_Start_Site	DEL	TCCTCGAGGCAGCC	TCCTCGAGGCAGCC	-	rs78182391		TCGA-RW-A68F-01A-11D-A35D-08	TCGA-RW-A68F-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5b7164ea-e35a-4a1f-ba8c-6b7131dd3fe0	394f8b07-8cbd-4f98-80a5-b757a66d82fe	g.chrX:51239296_51239309delTCCTCGAGGCAGCC	ENST00000375992.3	-	0	139_152					NM_018159.3	NP_060629.2	Q96G61	NUD11_HUMAN	nudix (nucleoside diphosphate linked moiety X)-type motif 11							cytoplasm	diphosphoinositol-polyphosphate diphosphatase activity|metal ion binding	p.?(5)		breast(1)|central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(2)|prostate(1)|upper_aerodigestive_tract(2)	9	Ovarian(276;0.236)					TTGCACTTCATCCTCGAGGCAGCCTCCTCGAGGC	0.692										HNSCC(48;0.14)			7	8	---	---	---	---					
