Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
IGF1R	3480	broad.mit.edu	37	15	99486194	99486194	+	Missense_Mutation	SNP	G	G	A			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr15:99486194G>A	ENST00000268035.6	+	19	4111	c.3500G>A	c.(3499-3501)cGg>cAg	p.R1167Q	IGF1R_ENST00000558762.1_Missense_Mutation_p.R1166Q	NM_000875.3	NP_000866.1	P08069	IGF1R_HUMAN	insulin-like growth factor 1 receptor	1167	Protein kinase.				anti-apoptosis|immune response|insulin receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of cell migration|positive regulation of cell proliferation|positive regulation of DNA replication|protein autophosphorylation|protein tetramerization	microsome	ATP binding|identical protein binding|insulin binding|insulin receptor binding|insulin receptor substrate binding|insulin-like growth factor I binding|insulin-like growth factor receptor activity|metal ion binding|phosphatidylinositol 3-kinase binding			NS(2)|breast(1)|central_nervous_system(1)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(13)|lung(20)|ovary(1)|prostate(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	63	all_cancers(4;4.17e-14)|all_epithelial(3;4.34e-15)|Lung NSC(78;0.00175)|all_lung(78;0.00351)|Melanoma(26;0.00505)|Medulloblastoma(229;0.163)		Epithelial(2;1.94e-12)|all cancers(5;6.83e-11)|BRCA - Breast invasive adenocarcinoma(2;2.88e-09)|OV - Ovarian serous cystadenocarcinoma(32;0.00261)		Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)|Mecasermin(DB01277)	GACTATTACCGGAAAGGAGGG	0.537000													4	71					0	0	1	0	0
AKR7A3	22977	broad.mit.edu	37	1	19615030	19615030	+	Silent	SNP	A	A	C	rs150259165	by1000genomes	TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr1:19615030A>C	ENST00000361640.4	-	1	714	c.174T>G	c.(172-174)ctT>ctG	p.L58L		NM_012067.2	NP_036199.2	O95154	ARK73_HUMAN	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	58					cellular aldehyde metabolic process	cytosol	aldo-keto reductase (NADP) activity|electron carrier activity			NS(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|lung(4)|ovary(1)|stomach(2)	13		Colorectal(325;3.46e-05)|Renal(390;0.000147)|all_lung(284;0.000321)|Lung NSC(340;0.000398)|Breast(348;0.00049)|Ovarian(437;0.00764)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00459)|BRCA - Breast invasive adenocarcinoma(304;1.78e-05)|Kidney(64;0.00016)|KIRC - Kidney renal clear cell carcinoma(64;0.00258)|GBM - Glioblastoma multiforme(114;0.00276)|STAD - Stomach adenocarcinoma(196;0.00644)|READ - Rectum adenocarcinoma(331;0.0649)		CCAGGCCGCCAAGGATGGTCT	0.697000													3	17					0	0	1	0	0
LINC00969	0	broad.mit.edu	37	3	195410689	195410689	+	RNA	SNP	C	C	T	rs6583275	by1000genomes	TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr3:195410689C>T	ENST00000445430.1	+	0	1886																											CTTTGAGGTGCACTGGAGGAA	0.567000													3	14					0	0	1	0	0
SPON1	10418	broad.mit.edu	37	11	14284285	14284285	+	RNA	SNP	C	C	G			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr11:14284285C>G	ENST00000310358.7	+	0	2559							Q9HCB6	SPON1_HUMAN	spondin 1, extracellular matrix protein						cell adhesion	extracellular space|proteinaceous extracellular matrix	protein binding			NS(1)|endometrium(1)|large_intestine(5)|lung(11)|prostate(2)|upper_aerodigestive_tract(1)	21				Epithelial(150;0.00898)		ACCGAGTGGTCCCAGTGGTCG	0.517000													5	15					0	0	1	0	0
SPON1	10418	broad.mit.edu	37	11	14284282	14284282	+	RNA	SNP	G	G	T			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr11:14284282G>T	ENST00000310358.7	+	0	2556							Q9HCB6	SPON1_HUMAN	spondin 1, extracellular matrix protein						cell adhesion	extracellular space|proteinaceous extracellular matrix	protein binding			NS(1)|endometrium(1)|large_intestine(5)|lung(11)|prostate(2)|upper_aerodigestive_tract(1)	21				Epithelial(150;0.00898)		CTCACCGAGTGGTCCCAGTGG	0.517000													5	16					0.0293803	0.0293803	1	1	0
FRG1B	0	broad.mit.edu	37	20	29633906	29633906	+	Missense_Mutation	SNP	A	A	T			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr20:29633906A>T	ENST00000278882.3	+	9	925	c.545A>T	c.(544-546)aAt>aTt	p.N182I	FRG1B_ENST00000358464.4_Missense_Mutation_p.N182I																endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						AGAGAACCAAATTGAAAGCCG	0.264000													3	58					0	0	1	0	0
LINC00969	0	broad.mit.edu	37	3	195410687	195410687	+	RNA	SNP	T	T	A	rs6583274	by1000genomes	TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr3:195410687T>A	ENST00000445430.1	+	0	1884																											CCCTTTGAGGTGCACTGGAGG	0.567000													3	15					0	0	1	0	0
STK40	83931	broad.mit.edu	37	1	36823840	36823840	+	Splice_Site	SNP	C	C	T			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr1:36823840C>T	ENST00000359297.2	-	3	349	c.342_splice	c.e3+1	p.Q114_splice	STK40_ENST00000482458.1_5'UTR|STK40_ENST00000373130.3_Splice_Site_p.Q119_splice|STK40_ENST00000373132.3_Splice_Site_p.Q114_splice|STK40_ENST00000373129.3_Splice_Site_p.Q114_splice			Q8N2I9	STK40_HUMAN	serine/threonine kinase 40	114	Protein kinase.					cytoplasm|nucleus	ATP binding|protein serine/threonine kinase activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(3)|ovary(1)|skin(1)|stomach(1)	13		Myeloproliferative disorder(586;0.0393)				GGCCGCTCACCTGGAAGAGGC	0.647000													6	20					0	0	1	0	0
CAGE1	285782	broad.mit.edu	37	6	7373788	7373788	+	Nonsense_Mutation	SNP	C	C	A			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr6:7373788C>A	ENST00000502583.1	-	5	1828	c.1264G>T	c.(1264-1266)Gaa>Taa	p.E422*	CAGE1_ENST00000338150.4_Nonsense_Mutation_p.E422*|CAGE1_ENST00000379918.4_Nonsense_Mutation_p.E422*|CAGE1_ENST00000512086.1_Nonsense_Mutation_p.E422*|CAGE1_ENST00000296742.7_Nonsense_Mutation_p.E286*	NM_001170692.1	NP_001164163.1	Q8TC20	CAGE1_HUMAN	cancer antigen 1	422										breast(1)|cervix(1)|endometrium(3)|kidney(2)|lung(11)|urinary_tract(1)	19	Ovarian(93;0.0418)					ATGTACCTTTCCTGTAAACAC	0.343000													6	37					1.6384e-10	1.87246e-10	1	1	0
LL22NC03-80A10.6	0	broad.mit.edu	37	22	22663087	22663087	+	RNA	SNP	A	A	G	rs1054158		TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr22:22663087A>G	ENST00000426066.1	+	0	526					NR_027293.1																						GCTGCCACATAAGTTGTCCTT	0.303000													3	29					0	0	1	0	0
BAGE2	85319	broad.mit.edu	37	21	11058353	11058353	+	RNA	SNP	T	T	C	rs79433933	by1000genomes	TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr21:11058353T>C	ENST00000470054.1	-	0	324									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		GAAATCTCTTTATAAAACCTT	0.343000													4	142					0	0	1	0	0
TAF9	6880	broad.mit.edu	37	5	68661172	68661172	+	Silent	SNP	A	A	C			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr5:68661172A>C	ENST00000328663.4	-	3	859	c.393T>G	c.(391-393)tcT>tcG	p.S131S	TAF9_ENST00000506736.1_Silent_p.S131S|TAF9_ENST00000502819.1_Intron|TAF9_ENST00000380818.3_Intron|TAF9_ENST00000380822.4_Intron|TAF9_ENST00000512561.1_Intron|TAF9_ENST00000217893.5_Silent_p.S131S	NM_001015892.1	NP_001015892.1	Q9Y3D8	KAD6_HUMAN	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa	0						Cajal body	adenylate kinase activity|ATP binding|protein binding			central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(4)|urinary_tract(1)	8		Lung NSC(167;7.26e-05)|Prostate(74;0.0143)|Ovarian(174;0.0448)|Breast(144;0.198)		OV - Ovarian serous cystadenocarcinoma(47;1.1e-56)|Epithelial(20;9.54e-53)|all cancers(19;2.2e-48)|Lung(70;0.0176)		TTTTCTGTAAAGATTTCAGCC	0.443000													9	165					0	0	1	0	0
ZNF287	57336	broad.mit.edu	37	17	16456249	16456249	+	Missense_Mutation	SNP	T	T	C			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr17:16456249T>C	ENST00000395824.1	-	6	1824	c.1207A>G	c.(1207-1209)Aaa>Gaa	p.K403E	ZNF287_ENST00000395825.3_Missense_Mutation_p.K403E			Q9HBT7	ZN287_HUMAN	zinc finger protein 287	396					viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(1)|endometrium(3)|kidney(2)|large_intestine(7)|lung(5)|prostate(1)|urinary_tract(1)	20				UCEC - Uterine corpus endometrioid carcinoma (92;0.083)		CTAAACTCTTTCCCACATTCT	0.428000													14	90					0	0	1	0	0
FADD	8772	broad.mit.edu	37	11	70052302	70052302	+	Missense_Mutation	SNP	G	G	C			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr11:70052302G>C	ENST00000301838.4	+	2	647	c.350G>C	c.(349-351)cGt>cCt	p.R117P		NM_003824.3	NP_003815.1	Q13158	FADD_HUMAN	Fas (TNFRSF6)-associated via death domain	117	Death.				activation of caspase activity|activation of pro-apoptotic gene products|cellular response to mechanical stimulus|defense response to virus|induction of apoptosis via death domain receptors|innate immune response|interspecies interaction between organisms|necrotic cell death|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of interleukin-8 production|positive regulation of transcription from RNA polymerase II promoter|positive regulation of tumor necrosis factor production|positive regulation of type I interferon-mediated signaling pathway|signal transduction	cytosol	death receptor binding|identical protein binding			endometrium(1)|lung(4)|ovary(1)|pancreas(1)|urinary_tract(2)	9	Esophageal squamous(2;1.19e-45)		LUSC - Lung squamous cell carcinoma(11;1.46e-14)|STAD - Stomach adenocarcinoma(18;0.0513)			AGGCTGGCTCGTCAGCTCAAA	0.498000													5	11					0	0	1	0	0
AKR7A3	22977	broad.mit.edu	37	1	19615023	19615023	+	Silent	SNP	G	G	A	rs115242113	by1000genomes	TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr1:19615023G>A	ENST00000361640.4	-	1	721	c.181C>T	c.(181-183)Ctg>Ttg	p.L61L		NM_012067.2	NP_036199.2	O95154	ARK73_HUMAN	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	61					cellular aldehyde metabolic process	cytosol	aldo-keto reductase (NADP) activity|electron carrier activity	p.L61L(1)		NS(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|lung(4)|ovary(1)|stomach(2)	13		Colorectal(325;3.46e-05)|Renal(390;0.000147)|all_lung(284;0.000321)|Lung NSC(340;0.000398)|Breast(348;0.00049)|Ovarian(437;0.00764)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00459)|BRCA - Breast invasive adenocarcinoma(304;1.78e-05)|Kidney(64;0.00016)|KIRC - Kidney renal clear cell carcinoma(64;0.00258)|GBM - Glioblastoma multiforme(114;0.00276)|STAD - Stomach adenocarcinoma(196;0.00644)|READ - Rectum adenocarcinoma(331;0.0649)		CGGAGCCCCAGGCCGCCAAGG	0.692000													4	15					0	0	1	0	0
OR8A1	390275	broad.mit.edu	37	11	124440082	124440082	+	Missense_Mutation	SNP	C	C	T			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr11:124440082C>T	ENST00000284287.3	+	1	190	c.118C>T	c.(118-120)Ctc>Ttc	p.L40F		NM_001005194.1	NP_001005194.1	Q8NGG7	OR8A1_HUMAN	olfactory receptor, family 8, subfamily A, member 1	40					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			haematopoietic_and_lymphoid_tissue(1)|lung(16)|ovary(2)|prostate(1)|skin(2)	22		Breast(109;0.0115)|Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|all_neural(223;0.224)		BRCA - Breast invasive adenocarcinoma(274;1.49e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0214)		GAGAGCAGACCTCCAGCTCCC	0.527000													23	13					0	0	1	0	0
FAM107A	11170	broad.mit.edu	37	3	58552410	58552410	+	Missense_Mutation	SNP	G	G	A			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr3:58552410G>A	ENST00000394481.1	-	5	898	c.340C>T	c.(340-342)Cca>Tca	p.P114S	FAM107A_ENST00000474531.1_Missense_Mutation_p.P145S|FAM107A_ENST00000447756.2_Missense_Mutation_p.P142S|FAM107A_ENST00000360997.2_Missense_Mutation_p.P114S|FAM107A_ENST00000464064.1_3'UTR	NM_007177.2	NP_009108.1	O95990	F107A_HUMAN	family with sequence similarity 107, member A	114					regulation of cell growth	nucleus	protein binding			breast(1)|endometrium(2)|large_intestine(2)|lung(4)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	13				BRCA - Breast invasive adenocarcinoma(55;0.000189)|Kidney(10;0.000536)|KIRC - Kidney renal clear cell carcinoma(10;0.000716)|OV - Ovarian serous cystadenocarcinoma(275;0.154)		TCCTTCTCTGGTGGTTTTTCC	0.537000													13	43					0	0	1	0	0
ATAD3B	83858	broad.mit.edu	37	1	1421933	1421933	+	Missense_Mutation	SNP	C	C	A			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr1:1421933C>A	ENST00000308647.7	+	11	1215	c.1099C>A	c.(1099-1101)Ctg>Atg	p.L367M		NM_031921.4	NP_114127.3	Q5T9A4	ATD3B_HUMAN	ATPase family, AAA domain containing 3B	367							ATP binding|nucleoside-triphosphatase activity			endometrium(2)|large_intestine(1)|lung(3)|ovary(1)|skin(2)|urinary_tract(1)	10	all_cancers(77;0.00164)|all_epithelial(69;0.000959)|all_lung(157;0.00963)|Lung NSC(156;0.0232)|Ovarian(185;0.0634)	all_epithelial(116;9.48e-15)|all_lung(118;9.67e-07)|Lung NSC(185;5.59e-05)|Renal(390;0.00571)|Breast(487;0.0183)|Hepatocellular(190;0.0268)|Myeloproliferative disorder(586;0.028)|Ovarian(437;0.127)|Lung SC(97;0.217)		Epithelial(90;1.79e-36)|OV - Ovarian serous cystadenocarcinoma(86;3.94e-22)|Colorectal(212;0.000155)|COAD - Colon adenocarcinoma(227;0.000193)|Kidney(185;0.00227)|BRCA - Breast invasive adenocarcinoma(365;0.00461)|STAD - Stomach adenocarcinoma(132;0.00644)|KIRC - Kidney renal clear cell carcinoma(229;0.0339)|Lung(427;0.145)		GAAACTCGCCCTGCACTCAGG	0.617000													6	36					6.40141e-05	6.67973e-05	1	1	0
ARHGEF15	22899	broad.mit.edu	37	17	8215743	8215743	+	Missense_Mutation	SNP	C	C	T			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr17:8215743C>T	ENST00000361926.3	+	2	496	c.386C>T	c.(385-387)aCg>aTg	p.T129M	ARHGEF15_ENST00000421050.1_Missense_Mutation_p.T129M	NM_173728.3	NP_776089.2	O94989	ARHGF_HUMAN	Rho guanine nucleotide exchange factor (GEF) 15	129	Pro-rich.				negative regulation of synapse maturation|regulation of Rho protein signal transduction	dendrite|intracellular	GTPase activator activity|Rho guanyl-nucleotide exchange factor activity			breast(1)|endometrium(9)|large_intestine(5)|lung(11)|ovary(5)|prostate(3)|skin(2)|urinary_tract(1)	37						TCACCCTGCACGCCTCTGCTC	0.672000													10	61					0	0	1	0	0
FAM131C	348487	broad.mit.edu	37	1	16385168	16385169	+	Frame_Shift_Ins	INS	-	-	G			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr1:16385168_16385169insG	ENST00000375662.4	-	7	789_790	c.606_607insC	c.(604-609)cccacafs	p.T203fs	FAM131C_ENST00000494078.1_5'UTR	NM_182623.2	NP_872429.2	Q96AQ9	F131C_HUMAN	family with sequence similarity 131, member C	203										large_intestine(2)|lung(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	8		Colorectal(325;3.46e-05)|Breast(348;0.000278)|Lung NSC(340;0.000419)|Renal(390;0.000518)|all_lung(284;0.000567)|Ovarian(437;0.0221)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0178)|Colorectal(212;8.32e-08)|COAD - Colon adenocarcinoma(227;5.56e-06)|BRCA - Breast invasive adenocarcinoma(304;9.12e-05)|Kidney(64;0.000163)|KIRC - Kidney renal clear cell carcinoma(64;0.00258)|STAD - Stomach adenocarcinoma(313;0.00656)|READ - Rectum adenocarcinoma(331;0.0649)		TCATCCTGTGAGGGGCCGCTGG	0.653													2	4	---	---	---	---					
SULT1E1	6783	broad.mit.edu	37	4	70713495	70713496	+	Frame_Shift_Del	DEL	CA	CA	-			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr4:70713495_70713496delCA	ENST00000226444.3	-	6	623_624	c.511_512delTG	c.(511-513)gfs	p.W171fs		NM_005420.2	NP_005411.1	P49888	ST1E1_HUMAN	sulfotransferase family 1E, estrogen-preferring, member 1	171					3'-phosphoadenosine 5'-phosphosulfate metabolic process|sulfation|xenobiotic metabolic process	cytosol|nuclear membrane	estrone sulfotransferase activity|flavonol 3-sulfotransferase activity|steroid binding|steroid sulfotransferase activity			central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(2)|ovary(1)|prostate(1)|skin(1)	10						ATGTTTATACCAGGAACCATAA	0.366													8	111	---	---	---	---					
JMJD8	339123	broad.mit.edu	37	16	733880	733880	+	Frame_Shift_Del	DEL	T	T	-			TCGA-S7-A7WQ-01A-12D-A35I-08	TCGA-S7-A7WQ-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	26df2cdd-832c-42bf-9238-8e6ab68e05bd	9bfbaaff-29f2-4e99-8004-e96622a04dbb	g.chr16:733880delT	ENST00000293882.4	-	3	415	c.416delA	c.(415-417)cgfs	p.Q139fs	JMJD8_ENST00000562824.1_Frame_Shift_Del_p.Q39fs|JMJD8_ENST00000562111.1_Frame_Shift_Del_p.Q69fs|JMJD8_ENST00000454700.1_Frame_Shift_Del_p.Q109fs|JMJD8_ENST00000412368.2_Frame_Shift_Del_p.Q90fs			Q96S16	JMJD8_HUMAN	jumonji domain containing 8	139										breast(1)	1						CGTGAGTCCCTGCAGGATGAC	0.741													2	4	---	---	---	---					
