Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
NOTCH4	4855	broad.mit.edu	37	6	32184732	32184732	+	Silent	SNP	A	A	G			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr6:32184732A>G	ENST00000375023.3	-	11	1989	c.1851T>C	c.(1849-1851)tcT>tcC	p.S617S		NM_004557.3	NP_004548.3	Q99466	NOTC4_HUMAN	notch 4	617	EGF-like 15; calcium-binding (Potential).				cell fate determination|embryo development|hemopoiesis|mammary gland development|negative regulation of endothelial cell differentiation|Notch receptor processing|Notch signaling pathway|patterning of blood vessels|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	cell surface|cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to plasma membrane|nucleoplasm	calcium ion binding|protein heterodimerization activity|receptor activity			NS(1)|autonomic_ganglia(1)|breast(4)|central_nervous_system(4)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(11)|lung(47)|ovary(5)|prostate(4)|skin(10)|upper_aerodigestive_tract(1)|urinary_tract(1)	100						CTGTGAAACCAGAGGGGCAGA	0.527000													12	39					0	0	1	0	0
AGO2	27161	broad.mit.edu	37	8	141551409	141551409	+	Missense_Mutation	SNP	G	G	A			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr8:141551409G>A	ENST00000220592.5	-	15	2000	c.1888C>T	c.(1888-1890)Cgc>Tgc	p.R630C	AGO2_ENST00000519980.1_Missense_Mutation_p.R630C	NM_012154.3	NP_036286.2			argonaute RISC catalytic component 2																		TGCTGCACGCGCACGGTGGCG	0.622000													3	19					0	0	1	0	0
KLHL23	151230	broad.mit.edu	37	2	170606207	170606207	+	Missense_Mutation	SNP	C	C	T			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr2:170606207C>T	ENST00000392647.2	+	4	1886	c.1642C>T	c.(1642-1644)Cgg>Tgg	p.R548W	KLHL23_ENST00000272797.4_Missense_Mutation_p.R548W|KLHL23_ENST00000602521.1_Missense_Mutation_p.R55W	NM_144711.5	NP_653312.2	Q8NBE8	KLH23_HUMAN	kelch-like family member 23	548										breast(1)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(6)|lung(4)|skin(1)|urinary_tract(1)	16						CAGTGCCATGCGGTCTCATGG	0.373000													4	100					0	0	1	0	0
OR6C76	390326	broad.mit.edu	37	12	55820078	55820078	+	Missense_Mutation	SNP	G	G	A			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr12:55820078G>A	ENST00000328314.3	+	1	41	c.41G>A	c.(40-42)gGt>gAt	p.G14D		NM_001005183.1	NP_001005183.1	A6NM76	O6C76_HUMAN	olfactory receptor, family 6, subfamily C, member 76	14					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|central_nervous_system(1)|large_intestine(3)|lung(4)|prostate(1)|skin(1)|soft_tissue(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	14						ATCCTTCTGGGTCTGACGGAT	0.373000													21	56					0	0	1	0	0
TRIO	7204	broad.mit.edu	37	5	14391061	14391061	+	Missense_Mutation	SNP	A	A	T			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr5:14391061A>T	ENST00000344204.4	+	27	4204	c.4180A>T	c.(4180-4182)Act>Tct	p.T1394S	TRIO_ENST00000509967.2_Missense_Mutation_p.T1345S|TRIO_ENST00000537187.1_Missense_Mutation_p.T1394S	NM_007118.2	NP_009049.2	O75962	TRIO_HUMAN	trio Rho guanine nucleotide exchange factor	1394	DH 1.				apoptosis|axon guidance|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|transmembrane receptor protein tyrosine phosphatase signaling pathway	cytosol	ATP binding|protein serine/threonine kinase activity|Rho guanyl-nucleotide exchange factor activity			NS(2)|breast(6)|central_nervous_system(4)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(21)|lung(34)|ovary(4)|prostate(2)|skin(11)|stomach(3)|upper_aerodigestive_tract(3)|urinary_tract(4)	118	Lung NSC(4;0.000742)					GCCTGATTCTACTCAGCTGAT	0.343000													17	56					0	0	1	0	0
RP11-156P1.3	0	broad.mit.edu	37	17	45127107	45127107	+	RNA	SNP	C	C	G	rs147409399	by1000genomes	TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr17:45127107C>G	ENST00000575173.1	-	0	418																											CCTTCGTTCACCCAAGAGCAT	0.592000													4	66					0	0	1	0	0
HNF1B	6928	broad.mit.edu	37	17	36099431	36099431	+	Splice_Site	SNP	G	G	A			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr17:36099431G>A	ENST00000225893.4	-	2	905	c.544_splice	c.e2+1	p.Q182_splice	HNF1B_ENST00000560016.1_Splice_Site_p.Q182_splice|HNF1B_ENST00000427275.2_Splice_Site_p.Q182_splice|HNF1B_ENST00000561193.1_Splice_Site_p.Q182_splice	NM_000458.2|NM_001165923.1	NP_000449.1|NP_001159395.1	P35680	HNF1B_HUMAN	HNF1 homeobox B	182					endocrine pancreas development|genitalia development|kidney development|positive regulation of transcription initiation from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|pronephric nephron tubule development|regulation of pronephros size	nucleus	DNA binding|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(2)|central_nervous_system(3)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(6)|kidney(3)|large_intestine(2)|liver(1)|lung(3)|ovary(3)|prostate(1)|skin(2)	28		Breast(25;0.00765)|Ovarian(249;0.15)	STAD - Stomach adenocarcinoma(1;0.0142)			AAACACTTACGTCGGAGGATC	0.547000													5	64					0	0	1	0	0
ZNF528	84436	broad.mit.edu	37	19	52919463	52919463	+	Missense_Mutation	SNP	C	C	G			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr19:52919463C>G	ENST00000360465.3	+	7	1784	c.1358C>G	c.(1357-1359)aCt>aGt	p.T453S	ZNF528_ENST00000391788.2_3'UTR	NM_032423.2	NP_115799.2	Q3MIS6	ZN528_HUMAN	zinc finger protein 528	453					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(13)|lung(6)|ovary(1)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)	39				GBM - Glioblastoma multiforme(134;0.00249)|OV - Ovarian serous cystadenocarcinoma(262;0.00817)		TCAGACCTTACTGCCCATTTT	0.373000													5	98					0	0	1	0	0
CYP2D7P1	0	broad.mit.edu	37	22	42538870	42538870	+	RNA	SNP	A	A	C	rs2982057	by1000genomes	TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr22:42538870A>C	ENST00000358097.4	-	0	449				CYP2D7P1_ENST00000424775.1_RNA|CYP2D7P1_ENST00000433992.1_RNA																endometrium(1)	1						CCATAGCGCGACAGGAACACC	0.687000													3	25					0	0	1	0	0
FAM47C	442444	broad.mit.edu	37	X	37028425	37028425	+	Missense_Mutation	SNP	A	A	G	rs145580328	byFrequency	TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chrX:37028425A>G	ENST00000358047.3	+	1	1994	c.1942A>G	c.(1942-1944)Aat>Gat	p.N648D		NM_001013736.2	NP_001013758.1	Q5HY64	FA47C_HUMAN	family with sequence similarity 47, member C	648								p.N648D(7)		breast(4)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(15)|lung(63)|ovary(6)|pancreas(1)|prostate(6)|skin(8)|upper_aerodigestive_tract(4)|urinary_tract(1)	120						GGAGCCTCCCAATACTGGAGT	0.642000													5	125					0	0	1	0	0
RP11-85G18.6	0	broad.mit.edu	37	10	27535352	27535352	+	RNA	SNP	G	G	A			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr10:27535352G>A	ENST00000574842.1	+	0	255																											AATCAAAGTCGTTAGTATTTC	0.383000													18	62					0	0	1	0	0
PCSK4	54760	broad.mit.edu	37	19	1490185	1490185	+	Missense_Mutation	SNP	C	C	T			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr19:1490185C>T	ENST00000300954.5	-	1	222	c.161G>A	c.(160-162)cGc>cAc	p.R54H	PCSK4_ENST00000587784.1_Intron	NM_017573.3	NP_060043.2	Q6UW60	PCSK4_HUMAN	proprotein convertase subtilisin/kexin type 4	54					proteolysis	integral to membrane	serine-type endopeptidase activity			cervix(2)|endometrium(2)|kidney(1)|lung(6)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)	15		Acute lymphoblastic leukemia(61;3.02e-13)|all_hematologic(61;4.32e-09)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		GCCGAATTTGCGTGCCAGGCG	0.687000													4	50					0	0	1	0	0
EP400	57634	broad.mit.edu	37	12	132547093	132547093	+	Silent	SNP	A	A	G	rs60608267	by1000genomes	TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr12:132547093A>G	ENST00000333577.4	+	48	8398	c.8289A>G	c.(8287-8289)caA>caG	p.Q2763Q	EP400_ENST00000332482.4_Silent_p.Q2690Q|EP400_ENST00000389561.2_Silent_p.Q2727Q|EP400_ENST00000389562.2_Silent_p.Q2726Q|EP400_ENST00000330386.6_Silent_p.Q2646Q			Q96L91	EP400_HUMAN	E1A binding protein p400	2763	Interaction with ZNF42 (By similarity).|Poly-Gln.				histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent	NuA4 histone acetyltransferase complex|nuclear speck	ATP binding|DNA binding|helicase activity	p.Q2726Q(9)		NS(1)|breast(6)|central_nervous_system(10)|cervix(1)|endometrium(21)|kidney(13)|large_intestine(25)|lung(56)|ovary(5)|prostate(8)|skin(6)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	161	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.198)		OV - Ovarian serous cystadenocarcinoma(86;3.01e-08)|Epithelial(86;3.43e-07)|all cancers(50;2.01e-06)		agcagcaacaacagcagcagc	0.567000													3	44					0	0	1	0	0
P4HA2	8974	broad.mit.edu	37	5	131546166	131546166	+	Missense_Mutation	SNP	G	G	A			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr5:131546166G>A	ENST00000401867.1	-	7	1088	c.520C>T	c.(520-522)Cgc>Tgc	p.R174C	P4HA2_ENST00000379100.2_Missense_Mutation_p.R174C|P4HA2_ENST00000379104.2_Missense_Mutation_p.R174C|P4HA2_ENST00000360568.3_Missense_Mutation_p.R174C|P4HA2_ENST00000166534.4_Missense_Mutation_p.R174C|P4HA2_ENST00000379086.1_Missense_Mutation_p.R174C			O15460	P4HA2_HUMAN	prolyl 4-hydroxylase, alpha polypeptide II	174						endoplasmic reticulum lumen	electron carrier activity|iron ion binding|L-ascorbic acid binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|procollagen-proline 4-dioxygenase activity|protein binding	p.R174C(1)		breast(1)|endometrium(3)|kidney(2)|large_intestine(4)|lung(8)|prostate(4)|skin(1)|upper_aerodigestive_tract(1)	24		all_cancers(142;0.103)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)		L-Proline(DB00172)|Succinic acid(DB00139)	TAGGCCGAGCGGCCCATCCCA	0.537000													22	354					0	0	1	0	0
BAGE2	85319	broad.mit.edu	37	21	11098863	11098863	+	RNA	SNP	A	A	G	rs75318310	by1000genomes	TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr21:11098863A>G	ENST00000470054.1	-	0	62									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		ccagcctccaactcccccttc	0.627000													3	19					0	0	1	0	0
FRG1B	0	broad.mit.edu	37	20	29628236	29628236	+	Missense_Mutation	SNP	G	G	C	rs145412486	by1000genomes	TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr20:29628236G>C	ENST00000278882.3	+	6	618	c.238G>C	c.(238-240)Gct>Cct	p.A80P	FRG1B_ENST00000439954.2_Missense_Mutation_p.A85P|FRG1B_ENST00000358464.4_Missense_Mutation_p.A80P														p.A80P(8)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						GGGGAAAATGGCTTTGTTGGC	0.363000													7	131					0	0	1	0	0
OR1J2	26740	broad.mit.edu	37	9	125273104	125273104	+	Silent	SNP	C	C	T			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr9:125273104C>T	ENST00000335302.5	+	1	24	c.24C>T	c.(22-24)agC>agT	p.S8S		NM_054107.1	NP_473448.1	Q8NGS2	OR1J2_HUMAN	olfactory receptor, family 1, subfamily J, member 2	8					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(3)|lung(8)|pancreas(1)|skin(7)|stomach(1)	26						ACCAGAGCAGCGTGTCCGAGT	0.527000													4	96					0	0	1	0	0
NOTCH1	4851	broad.mit.edu	37	9	139414008	139414008	+	Missense_Mutation	SNP	C	C	T			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr9:139414008C>T	ENST00000277541.6	-	5	827	c.752G>A	c.(751-753)gGc>gAc	p.G251D		NM_017617.3	NP_060087.3	P46531	NOTC1_HUMAN	notch 1	251	EGF-like 6.				aortic valve morphogenesis|immune response|negative regulation of BMP signaling pathway|negative regulation of cell-substrate adhesion|negative regulation of myoblast differentiation|negative regulation of osteoblast differentiation|negative regulation of transcription, DNA-dependent|Notch receptor processing	cytosol|endoplasmic reticulum lumen|extracellular region|Golgi lumen|integral to membrane|nucleoplasm|plasma membrane	calcium ion binding|protein binding|receptor activity			breast(16)|central_nervous_system(17)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1183)|kidney(4)|large_intestine(1)|lung(57)|oesophagus(2)|ovary(3)|pancreas(1)|prostate(3)|skin(21)|upper_aerodigestive_tract(39)|urinary_tract(3)	1359	all_cancers(76;0.223)	Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;5.34e-06)|Epithelial(140;7.77e-06)		ACAGTTCTGGCCGGTGAAGCC	0.622000			"""T, Mis, O"""	TRB@	T-ALL					HNSCC(8;0.001)			5	217					0	0	1	0	0
ALG6	29929	broad.mit.edu	37	1	63877718	63877718	+	Frame_Shift_Del	DEL	C	C	-			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr1:63877718delC	ENST00000371108.4	+	9	1107	c.802delC	c.(802-804)gtfs	p.R268fs	ALG6_ENST00000263440.4_Frame_Shift_Del_p.R270fs	NM_013339.3	NP_037471.2	Q9Y672	ALG6_HUMAN	ALG6, alpha-1,3-glucosyltransferase	268					dolichol-linked oligosaccharide biosynthetic process|post-translational protein modification|protein N-linked glycosylation via asparagine	endoplasmic reticulum membrane|integral to membrane	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity			endometrium(1)|large_intestine(4)|lung(5)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	13						CCCGGTTGATCGTGGATTATT	0.438													42	140	---	---	---	---					
RP11-782C8.2	0	broad.mit.edu	37	1	143196702	143196702	+	RNA	DEL	T	T	-			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr1:143196702delT	ENST00000412204.2	-	0	1892				RP11-782C8.1_ENST00000438000.1_lincRNA																							CCTGTTGTACTTTTTTCATAG	0.313													2	4	---	---	---	---					
RP11-649A16.1	0	broad.mit.edu	37	3	146995077	146995077	+	RNA	DEL	A	A	-			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr3:146995077delA	ENST00000473299.1	-	0	132																											TCTGGACTGtaaaaaaaaaaa	0.294													4	3	---	---	---	---					
ZIC2	7546	broad.mit.edu	37	13	100635008	100635010	+	In_Frame_Del	DEL	CCA	CCA	-			TCGA-SR-A6N0-01A-11D-A35I-08	TCGA-SR-A6N0-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	031b30f4-2a2d-4cb5-a2b3-5c3bb6a32394	58d7aaf7-14d1-443c-8b7b-48a900d22a8a	g.chr13:100635008_100635010delCCA	ENST00000376335.3	+	1	983_985	c.690_692delCCA	c.(688-693)gcc>gc	p.AH230del		NM_007129.3	NP_009060.2	O95409	ZIC2_HUMAN	Zic family member 2	230	Necessary for interaction with MDFIC and transcriptional activation or repression (By similarity).|Poly-Ala.				brain development|negative regulation of transcription, DNA-dependent|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription, DNA-dependent|visual perception	cytoplasm|nucleus	chromatin DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			large_intestine(2)|liver(2)|lung(5)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	13	all_neural(89;0.0837)|Medulloblastoma(90;0.18)|Lung SC(71;0.184)					CAGCCGCGGCccaccaccaccac	0.621													7	54	---	---	---	---					
