Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ZDHHC24	254359	broad.mit.edu	37	11	66307235	66307235	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr11:66307235G>A	ENST00000310442.3	-	3	854	c.620C>T	c.(619-621)gCg>gTg	p.A207V	ZDHHC24_ENST00000526986.1_Intron	NM_207340.1	NP_997223.1	Q6UX98	ZDH24_HUMAN	zinc finger, DHHC-type containing 24	207	Leu-rich.					integral to membrane	acyltransferase activity|zinc ion binding			endometrium(1)|large_intestine(3)|ovary(1)|prostate(1)|skin(1)	7						GCACAGCAGCGCACCCGCCAC	0.647000													3	20					0	0	1	0	0
WDFY3	23001	broad.mit.edu	37	4	85636525	85636525	+	Silent	SNP	C	C	A			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr4:85636525C>A	ENST00000322366.6	-	49	8243	c.7836G>T	c.(7834-7836)gtG>gtT	p.V2612V	WDFY3_ENST00000295888.4_Silent_p.V2629V			Q8IZQ1	WDFY3_HUMAN	WD repeat and FYVE domain containing 3	2629						cytoplasmic part|extrinsic to membrane|nuclear envelope	1-phosphatidylinositol binding|metal ion binding|protein binding			breast(5)|central_nervous_system(5)|endometrium(15)|haematopoietic_and_lymphoid_tissue(3)|kidney(8)|large_intestine(32)|lung(50)|ovary(3)|prostate(5)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(2)	134		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.000808)		AGAAAACTTCCACAGCAATAG	0.318000													26	26					2.27525e-19	2.37867e-19	1	1	0
POTEC	388468	broad.mit.edu	37	18	14513764	14513764	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr18:14513764C>T	ENST00000358970.5	-	10	1429	c.1430G>A	c.(1429-1431)cGg>cAg	p.R477Q		NM_001137671.1	NP_001131143.1	B2RU33	POTEC_HUMAN	POTE ankyrin domain family, member C	477								p.R477Q(12)		NS(2)|breast(1)|endometrium(9)|kidney(13)|lung(14)|prostate(3)|skin(6)|soft_tissue(1)|urinary_tract(3)	52						AAGTTGTTTCCGGGTATCATT	0.358000													5	106					0	0	1	0	0
CYP2U1	113612	broad.mit.edu	37	4	108866589	108866589	+	Silent	SNP	A	A	T			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr4:108866589A>T	ENST00000332884.6	+	2	1229	c.954A>T	c.(952-954)atA>atT	p.I318I	CYP2U1_ENST00000508453.1_Silent_p.I109I|RP11-286E11.1_ENST00000513071.1_RNA	NM_183075.2	NP_898898.1	Q7Z449	CP2U1_HUMAN	cytochrome P450, family 2, subfamily U, polypeptide 1	318					xenobiotic metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	aromatase activity|electron carrier activity|heme binding|oxygen binding			breast(1)|large_intestine(2)|lung(4)|skin(2)|urinary_tract(1)	10		Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;0.000128)		AGGACTTCATAGACATGTACC	0.348000													4	51					0	0	1	0	0
RP11-156P1.3	0	broad.mit.edu	37	17	45127107	45127107	+	RNA	SNP	C	C	G	rs147409399	by1000genomes	TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr17:45127107C>G	ENST00000575173.1	-	0	418																											CCTTCGTTCACCCAAGAGCAT	0.592000													5	43					0	0	1	0	0
POM121	9883	broad.mit.edu	37	7	72398976	72398976	+	Missense_Mutation	SNP	A	A	G	rs147859349		TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr7:72398976A>G	ENST00000395270.1	+	7	1322	c.281A>G	c.(280-282)aAt>aGt	p.N94S	POM121_ENST00000446813.1_Missense_Mutation_p.N94S|POM121_ENST00000257622.4_Missense_Mutation_p.N94S|POM121_ENST00000434423.2_Missense_Mutation_p.N359S|POM121_ENST00000358357.3_Missense_Mutation_p.N94S	NM_001257190.1	NP_001244119.1	Q96HA1	P121A_HUMAN	POM121 transmembrane nucleoporin	359	Pore side (Potential).|Required for targeting to the nucleus and nuclear pore complex.				carbohydrate metabolic process|glucose transport|mRNA transport|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	endoplasmic reticulum membrane|nuclear membrane|nuclear pore				NS(1)|breast(1)|endometrium(9)|kidney(4)|large_intestine(6)|lung(12)|prostate(3)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	41		Lung NSC(55;0.163)				CTGGTGGCCAATGGAGTCCCC	0.468000													5	144					0	0	1	0	0
MRI1	84245	broad.mit.edu	37	19	13879776	13879776	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr19:13879776G>A	ENST00000319545.8	+	5	779	c.722G>A	c.(721-723)cGt>cAt	p.R241H	MRI1_ENST00000040663.6_Missense_Mutation_p.R288H	NM_032285.2	NP_115661.1	Q9BV20	MTNA_HUMAN	methylthioribose-1-phosphate isomerase 1	288					L-methionine salvage from methylthioadenosine	cell projection|cytoplasm|nucleus	identical protein binding|S-methyl-5-thioribose-1-phosphate isomerase activity			breast(1)|large_intestine(1)|lung(2)|ovary(1)|prostate(1)	6						TGTGACCTCCGTCTGGAGACC	0.592000													17	13					0	0	1	0	0
PLCL1	5334	broad.mit.edu	37	2	198950399	198950399	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr2:198950399C>T	ENST00000428675.1	+	2	2556	c.2158C>T	c.(2158-2160)Cct>Tct	p.P720S	PLCL1_ENST00000437704.2_Missense_Mutation_p.P622S	NM_006226.3	NP_006217.3	Q15111	PLCL1_HUMAN	phospholipase C-like 1	720	C2.				intracellular signal transduction|lipid metabolic process	cytoplasm	calcium ion binding|phosphatidylinositol phospholipase C activity|signal transducer activity			autonomic_ganglia(1)|breast(1)|cervix(1)|endometrium(8)|kidney(1)|large_intestine(14)|lung(44)|ovary(1)|pancreas(2)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	80					Quinacrine(DB01103)	TGGGGTGTCTCCTCTAGCTCT	0.448000													37	51					0	0	1	0	0
OMD	4958	broad.mit.edu	37	9	95179741	95179741	+	Missense_Mutation	SNP	C	C	G			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr9:95179741C>G	ENST00000375550.4	-	2	375	c.100G>C	c.(100-102)Gag>Cag	p.E34Q	CENPP_ENST00000375587.3_Intron	NM_005014.2	NP_005005.1	Q99983	OMD_HUMAN	osteomodulin	34					cell adhesion	proteinaceous extracellular matrix				breast(1)|endometrium(1)|kidney(2)|large_intestine(4)|lung(3)|ovary(3)|skin(2)	16						TCATCTGGCTCTTGGTCATAG	0.363000			T	USP6	aneurysmal bone cysts								23	31					0	0	1	0	0
OR1J1	347168	broad.mit.edu	37	9	125239932	125239932	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr9:125239932C>T	ENST00000259357.2	-	1	303	c.274G>A	c.(274-276)Gtc>Atc	p.V92I		NM_001004451.1	NP_001004451.1	Q8NGS3	OR1J1_HUMAN	olfactory receptor, family 1, subfamily J, member 1	92					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(1)|large_intestine(4)|lung(6)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	16						TTGTAAAAGACGGCTAGGTGC	0.423000													30	52					0	0	1	0	0
ZFYVE28	57732	broad.mit.edu	37	4	2306616	2306616	+	Nonsense_Mutation	SNP	G	G	T			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr4:2306616G>T	ENST00000290974.2	-	8	1790	c.1451C>A	c.(1450-1452)tCg>tAg	p.S484*	RP11-478C1.7_ENST00000510632.1_RNA|ZFYVE28_ENST00000515312.1_Nonsense_Mutation_p.S414*|ZFYVE28_ENST00000511071.1_Nonsense_Mutation_p.S454*	NM_020972.2	NP_066023.2	Q9HCC9	LST2_HUMAN	zinc finger, FYVE domain containing 28	484					negative regulation of epidermal growth factor receptor activity	cytosol|early endosome membrane	metal ion binding|phosphatidylinositol-3-phosphate binding|protein binding			NS(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(17)|ovary(1)|pancreas(1)|prostate(1)|skin(4)	31						GTGCAGCCGCGAGTCCAGGCA	0.662000													3	57					1	1	1	1	0
TUBGCP6	85378	broad.mit.edu	37	22	50659143	50659143	+	Silent	SNP	G	G	A	rs143650291		TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr22:50659143G>A	ENST00000439308.2	-	16	4137	c.3645C>T	c.(3643-3645)caC>caT	p.H1215H	TUBGCP6_ENST00000248846.5_Silent_p.H1215H|TUBGCP6_ENST00000491449.1_5'UTR	NM_020461.3	NP_065194.2	Q96RT7	GCP6_HUMAN	tubulin, gamma complex associated protein 6	1215	9 X 27 AA tandem repeats.				G2/M transition of mitotic cell cycle|microtubule nucleation	centrosome|cytosol|gamma-tubulin ring complex|microtubule|spindle pole	microtubule binding			breast(4)|central_nervous_system(2)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|lung(13)|ovary(3)|prostate(2)|skin(2)	45		all_cancers(38;5.79e-13)|all_epithelial(38;1.71e-11)|all_lung(38;3.89e-05)|Breast(42;0.000523)|Lung NSC(38;0.000992)|Ovarian(80;0.0221)|Hepatocellular(38;0.0691)|Lung SC(80;0.113)		LUAD - Lung adenocarcinoma(64;0.109)|BRCA - Breast invasive adenocarcinoma(115;0.21)		ACACATGTCCGTGGGTGTTCC	0.622000													3	55					0	0	1	0	0
CSDE1	7812	broad.mit.edu	37	1	115267956	115267956	+	Splice_Site	SNP	T	T	A			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr1:115267956T>A	ENST00000438362.2	-	15	2157		c.e15-2		CSDE1_ENST00000339438.6_Splice_Site|CSDE1_ENST00000261443.5_Splice_Site|CSDE1_ENST00000369530.1_Splice_Site|CSDE1_ENST00000358528.4_Splice_Site|CSDE1_ENST00000534699.1_Splice_Site|CSDE1_ENST00000530886.1_Splice_Site	NM_001242891.1	NP_001229820.1	O75534	CSDE1_HUMAN	cold shock domain containing E1, RNA-binding						male gonad development|regulation of transcription, DNA-dependent	cytoplasm	DNA binding|protein binding|RNA binding			NS(1)|breast(4)|endometrium(11)|kidney(2)|large_intestine(12)|lung(17)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)	51	all_epithelial(7;5.11e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;2.21e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		GAGAACTCACTAAGGAGAAAG	0.403000													50	17					0	0	1	0	0
IFIT3	3437	broad.mit.edu	37	10	91099316	91099316	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr10:91099316G>A	ENST00000371818.4	+	2	1084	c.904G>A	c.(904-906)Gga>Aga	p.G302R	LIPA_ENST00000371837.1_Intron|LIPA_ENST00000487618.1_Intron|IFIT3_ENST00000371811.4_Missense_Mutation_p.G302R	NM_001549.4	NP_001540.2	O14879	IFIT3_HUMAN	interferon-induced protein with tetratricopeptide repeats 3	302					type I interferon-mediated signaling pathway		protein binding			breast(1)|central_nervous_system(3)|endometrium(1)|large_intestine(4)|lung(3)|skin(2)|urinary_tract(1)	15						TGAAGCTAGTGGAAATAAAGA	0.413000													31	17					0	0	1	0	0
REPS1	85021	broad.mit.edu	37	6	139266690	139266690	+	Missense_Mutation	SNP	T	T	C			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr6:139266690T>C	ENST00000450536.2	-	3	996	c.422A>G	c.(421-423)aAg>aGg	p.K141R	REPS1_ENST00000367663.4_Missense_Mutation_p.K141R|REPS1_ENST00000258062.5_Missense_Mutation_p.K141R|REPS1_ENST00000415951.2_Missense_Mutation_p.K141R|REPS1_ENST00000409812.2_Missense_Mutation_p.K141R			Q96D71	REPS1_HUMAN	RALBP1 associated Eps domain containing 1	141						coated pit|plasma membrane	calcium ion binding|SH3 domain binding			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(5)|lung(8)|upper_aerodigestive_tract(2)	19				GBM - Glioblastoma multiforme(68;0.000434)|OV - Ovarian serous cystadenocarcinoma(155;0.000548)		TACGGATCCCTTTTTCACTTG	0.478000													4	222					0	0	1	0	0
CDC45	8318	broad.mit.edu	37	22	19471512	19471512	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr22:19471512G>A	ENST00000407835.1	+	6	726	c.470G>A	c.(469-471)cGc>cAc	p.R157H	CDC45_ENST00000404724.3_Missense_Mutation_p.R111H|CDC45_ENST00000263201.1_Missense_Mutation_p.R157H|CDC45_ENST00000483431.1_3'UTR|CDC45_ENST00000437685.2_Missense_Mutation_p.R157H			O75419	CDC45_HUMAN	cell division cycle 45	157					DNA replication checkpoint|DNA strand elongation involved in DNA replication|DNA-dependent DNA replication initiation|M/G1 transition of mitotic cell cycle|regulation of transcription involved in G1/S phase of mitotic cell cycle|S phase of mitotic cell cycle	centrosome|nucleoplasm	protein binding			breast(1)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(2)|lung(7)|prostate(2)|skin(1)	19						TCTGAGAAGCGCACACGGTTA	0.532000													3	54					0	0	1	0	0
RP11-798G7.5	0	broad.mit.edu	37	17	43587576	43587576	+	RNA	SNP	A	A	G	rs145439557	by1000genomes	TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr17:43587576A>G	ENST00000253803.2	+	0	267				LRRC37A4P_ENST00000579913.1_RNA																							tctgaaaagaaaagaaaaaaa	0.428000													4	31					0	0	1	0	0
RP11-798G7.5	0	broad.mit.edu	37	17	43587569	43587569	+	RNA	SNP	G	G	C	rs149697015	by1000genomes	TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr17:43587569G>C	ENST00000253803.2	+	0	267				LRRC37A4P_ENST00000579913.1_RNA																							aactccgtctgaaaagaaaag	0.443000													3	25					0	0	1	0	0
PODXL	5420	broad.mit.edu	37	7	131241096	131241096	+	Frame_Shift_Del	DEL	G	G	-			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr7:131241096delG	ENST00000541194.1	-	1	280	c.23delC	c.(22-24)tgfs	p.S8fs	PODXL_ENST00000378555.3_Frame_Shift_Del_p.S8fs|PODXL_ENST00000322985.9_Frame_Shift_Del_p.S8fs|PODXL_ENST00000465001.1_Intron|PODXL_ENST00000537928.1_Frame_Shift_Del_p.S8fs	NM_001018111.2	NP_001018121.1	O00592	PODXL_HUMAN	podocalyxin-like	8					cell adhesion|epithelial tube formation|negative regulation of cell-cell adhesion|positive regulation of cell migration|positive regulation of cell-cell adhesion mediated by integrin|regulation of microvillus assembly	actin cytoskeleton|apical plasma membrane|centrosome|filopodium|integral to plasma membrane|lamellipodium|membrane raft|microvillus membrane|nucleolus|ruffle				NS(1)|breast(3)|endometrium(3)|kidney(3)|large_intestine(4)|lung(4)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	24	Melanoma(18;0.162)					CAGCAGCGCCGAGAGCGCCAG	0.741													2	4	---	---	---	---					
ALDH2	217	broad.mit.edu	37	12	112204841	112204843	+	In_Frame_Del	DEL	GCC	GCC	-			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr12:112204841_112204843delGCC	ENST00000261733.2	+	1	116_118	c.55_57delGCC	c.(55-57)del	p.A21del	RP11-162P23.2_ENST00000546840.2_Intron|ALDH2_ENST00000416293.3_In_Frame_Del_p.A21del	NM_000690.3	NP_000681.2	P05091	ALDH2_HUMAN	aldehyde dehydrogenase 2 family (mitochondrial)	21					carbohydrate metabolic process|ethanol oxidation|neurotransmitter biosynthetic process|xenobiotic metabolic process	mitochondrial matrix	aldehyde dehydrogenase|aldehyde dehydrogenase (NAD) activity|electron carrier activity			NS(1)|central_nervous_system(1)|endometrium(2)|kidney(2)|large_intestine(3)|liver(1)|lung(6)|ovary(2)|prostate(1)|skin(2)|stomach(1)	22					Disulfiram(DB00822)|Guanidine(DB00536)|NADH(DB00157)|Nitroglycerin(DB00727)	CCTCTTGTCAGCCGCCGCCACCC	0.734			T	HMGA2	leiomyoma								2	4	---	---	---	---					
ADCY4	196883	broad.mit.edu	37	14	24801744	24801744	+	Frame_Shift_Del	DEL	G	G	-			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr14:24801744delG	ENST00000310677.4	-	4	616	c.503delC	c.(502-504)ctfs	p.P168fs	ADCY4_ENST00000396747.3_5'UTR|ADCY4_ENST00000554068.2_Frame_Shift_Del_p.P168fs|RP11-934B9.3_ENST00000555591.1_Frame_Shift_Del_p.A234fs|ADCY4_ENST00000418030.2_Frame_Shift_Del_p.P168fs	NM_001198568.1|NM_001198592.1|NM_139247.3	NP_001185497.1|NP_001185521.1|NP_640340.2	Q8NFM4	ADCY4_HUMAN	adenylate cyclase 4	168					activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity|activation of protein kinase A activity|cellular response to glucagon stimulus|energy reserve metabolic process|inhibition of adenylate cyclase activity by G-protein signaling pathway|nerve growth factor receptor signaling pathway|synaptic transmission|transmembrane transport|water transport	cytoplasm|integral to membrane|plasma membrane	adenylate cyclase activity|ATP binding|metal ion binding|protein binding			cervix(1)|endometrium(1)|kidney(1)|large_intestine(10)|lung(13)|ovary(2)|pancreas(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	34				GBM - Glioblastoma multiforme(265;0.0192)		CAGCAGTGCAGGCCGTGAGTC	0.662											OREG0022624	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	2	4	---	---	---	---					
GTF2A1	2957	broad.mit.edu	37	14	81646632	81646643	+	In_Frame_Del	DEL	CATCCTTGAGAT	CATCCTTGAGAT	-			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr14:81646632_81646643delCATCCTTGAGAT	ENST00000553612.1	-	9	1458_1469	c.1055_1066delATCTCAAGGATG	c.(1054-1068)cgc>c	p.HLKDG352del	GTF2A1_ENST00000434192.2_In_Frame_Del_p.HLKDG313del	NM_015859.3	NP_056943.1	P52655	TF2AA_HUMAN	general transcription factor IIA, 1, 19/37kDa	352					regulation of transcription, DNA-dependent|transcription elongation from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|viral reproduction	cytoplasm|transcription factor TFIIA complex	DNA binding|protein binding|protein heterodimerization activity|TBP-class protein binding|transcription coactivator activity			breast(1)|endometrium(1)|kidney(2)|large_intestine(2)|lung(5)|upper_aerodigestive_tract(1)	12				BRCA - Breast invasive adenocarcinoma(234;0.0287)		TTCATAATGCCATCCTTGAGATGAAATTTCCA	0.274													24	111	---	---	---	---					
DNM1P47	0	broad.mit.edu	37	15	102299886	102299887	+	RNA	INS	-	-	G			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr15:102299886_102299887insG	ENST00000561463.1	+	0	7932_7933																											AACCTGTACTCGCGTCGGAACC	0.589													3	6	---	---	---	---					
MYO18A	399687	broad.mit.edu	37	17	27423926	27423927	+	Frame_Shift_Ins	INS	-	-	C			TCGA-WB-A80M-01A-11D-A35I-08	TCGA-WB-A80M-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0cbee6b0-22b5-4a22-a79d-88867205e64b	01134613-e4be-423c-8a3f-0c3307fcb112	g.chr17:27423926_27423927insC	ENST00000527372.1	-	28	4417_4418	c.4237_4238insG	c.(4237-4239)cctfs	p.P1413fs	MYO18A_ENST00000533112.1_Frame_Shift_Ins_p.P1413fs|MYO18A_ENST00000531253.1_Frame_Shift_Ins_p.P1413fs|MYO18A_ENST00000354329.4_Frame_Shift_Ins_p.P1413fs	NM_078471.3	NP_510880.2	Q92614	MY18A_HUMAN	myosin XVIIIA	1413					anti-apoptosis|DNA metabolic process	ER-Golgi intermediate compartment|myosin complex	ATP binding|DNA binding|DNA-dependent ATPase activity|identical protein binding|motor activity			NS(1)|cervix(1)|endometrium(6)|kidney(6)|lung(20)|urinary_tract(2)	36			Epithelial(11;4.97e-05)|BRCA - Breast invasive adenocarcinoma(11;0.000221)|all cancers(11;0.000234)|Colorectal(6;0.0102)|COAD - Colon adenocarcinoma(6;0.031)			TGCCTGCAGGTCCCCGAGCTAG	0.589													2	4	---	---	---	---					
