Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
RP11-146E13.4	0	broad.mit.edu	37	14	19857036	19857036	+	RNA	SNP	A	A	G			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr14:19857036A>G	ENST00000548109.1	+	0	72																											CTGGATAATAAAGTTCATCTC	0.373000													4	127					0	0	1	0	0
TUBB8P7	0	broad.mit.edu	37	16	90161578	90161578	+	RNA	SNP	G	G	A	rs13337896	by1000genomes	TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr16:90161578G>A	ENST00000564451.1	+	0	931				TUBB8P7_ENST00000567960.1_RNA														p.R105H(3)									GCCAAGGGACGCTACACCGAA	0.587000													5	32					0	0	1	0	0
PARD3B	117583	broad.mit.edu	37	2	205829978	205829978	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr2:205829978C>T	ENST00000406610.2	+	3	533	c.326C>T	c.(325-327)gCc>gTc	p.A109V	PARD3B_ENST00000358768.2_Missense_Mutation_p.A109V|PARD3B_ENST00000351153.1_Missense_Mutation_p.A109V|PARD3B_ENST00000462231.1_Missense_Mutation_p.A109V|PARD3B_ENST00000349953.3_Missense_Mutation_p.A109V	NM_057177.6|NM_152526.5|NM_205863.3	NP_476518.4|NP_689739.4|NP_995585.2	Q8TEW8	PAR3L_HUMAN	par-3 family cell polarity regulator beta	109					cell cycle|cell division	endomembrane system|tight junction				breast(1)|endometrium(9)|kidney(2)|large_intestine(6)|liver(4)|lung(33)|ovary(1)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(4)	65		all_cancers(1;2.88e-06)|all_epithelial(1;3.23e-06)		Epithelial(149;0.0739)		ACAGAAGTGGCCGCCCAACTG	0.468000													4	56					0	0	1	0	0
MGA	23269	broad.mit.edu	37	15	42035001	42035001	+	Missense_Mutation	SNP	A	A	G			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr15:42035001A>G	ENST00000219905.7	+	15	5024	c.4843A>G	c.(4843-4845)Atg>Gtg	p.M1615V	MGA_ENST00000570161.1_Missense_Mutation_p.M1615V|MGA_ENST00000545763.1_Intron|MGA_ENST00000389936.4_Missense_Mutation_p.M1615V|MGA_ENST00000566586.1_Intron	NM_001164273.1	NP_001157745.1	Q8IWI9	MGAP_HUMAN	MGA, MAX dimerization protein	1615	Thr-rich.					MLL1 complex	DNA binding|sequence-specific DNA binding transcription factor activity			NS(1)|breast(4)|central_nervous_system(3)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(18)|lung(33)|ovary(8)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	95		all_cancers(109;0.00356)|all_epithelial(112;0.0413)|all_lung(180;0.18)|Ovarian(310;0.238)		OV - Ovarian serous cystadenocarcinoma(18;1.41e-18)|GBM - Glioblastoma multiforme(113;2.15e-06)|COAD - Colon adenocarcinoma(120;0.031)|Lung(196;0.0721)|BRCA - Breast invasive adenocarcinoma(123;0.0964)|Colorectal(105;0.0998)|LUSC - Lung squamous cell carcinoma(244;0.235)		TGTGACACCTATGACTGCTAT	0.463000													16	36					0	0	1	0	0
NCOA6	23054	broad.mit.edu	37	20	33345744	33345744	+	Silent	SNP	C	C	T			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr20:33345744C>T	ENST00000374796.2	-	8	3377	c.807G>A	c.(805-807)caG>caA	p.Q269Q	NCOA6_ENST00000359003.2_Silent_p.Q269Q			Q14686	NCOA6_HUMAN	nuclear receptor coactivator 6	269	CREBBP-binding region.|Gln-rich.|NCOA1-binding region.|TBP/GTF2A-binding region.				brain development|cellular lipid metabolic process|DNA recombination|DNA repair|DNA replication|estrogen receptor signaling pathway|glucocorticoid receptor signaling pathway|heart development|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|response to hormone stimulus|transcription initiation from RNA polymerase II promoter	transcription factor complex	chromatin binding|enzyme binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoid X receptor binding|thyroid hormone receptor binding	p.Q269Q(15)		NS(2)|breast(6)|central_nervous_system(3)|cervix(1)|endometrium(9)|kidney(8)|large_intestine(16)|lung(37)|ovary(4)|prostate(5)|skin(13)|upper_aerodigestive_tract(2)|urinary_tract(1)	107						gctgctgctgctgttgttgtt	0.537000													3	24					0	0	1	0	0
HMCN1	83872	broad.mit.edu	37	1	186008083	186008083	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr1:186008083G>A	ENST00000271588.4	+	38	6203	c.5974G>A	c.(5974-5976)Gtg>Atg	p.V1992M	HMCN1_ENST00000367492.2_Missense_Mutation_p.V1992M	NM_031935.2	NP_114141.2	Q96RW7	HMCN1_HUMAN	hemicentin 1	1992	Ig-like C2-type 17.				response to stimulus|visual perception	basement membrane	calcium ion binding			NS(2)|autonomic_ganglia(1)|breast(10)|central_nervous_system(2)|cervix(1)|endometrium(28)|haematopoietic_and_lymphoid_tissue(4)|kidney(13)|large_intestine(58)|liver(3)|lung(101)|ovary(23)|pancreas(4)|prostate(20)|skin(8)|stomach(1)|upper_aerodigestive_tract(11)|urinary_tract(18)	308						ATATAAATGCGTGGCCATCAA	0.438000													4	80					0	0	1	0	0
DNER	92737	broad.mit.edu	37	2	230272009	230272009	+	Silent	SNP	G	G	A			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr2:230272009G>A	ENST00000341772.4	-	10	1796	c.1662C>T	c.(1660-1662)aaC>aaT	p.N554N		NM_139072.3	NP_620711.3	Q8NFT8	DNER_HUMAN	delta/notch-like EGF repeat containing	554	EGF-like 9.|Follistatin-like.				central nervous system development|endocytosis|neuron migration|Notch signaling pathway|synapse assembly	dendrite|early endosome|integral to membrane|plasma membrane	calcium ion binding|clathrin binding|transmembrane receptor activity			NS(2)|breast(1)|endometrium(7)|kidney(1)|large_intestine(13)|liver(1)|lung(28)|ovary(2)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	63		all_lung(227;0.00413)|Renal(207;0.0113)|Lung NSC(271;0.0211)|all_hematologic(139;0.105)|Acute lymphoblastic leukemia(138;0.175)		Epithelial(121;1.4e-11)|all cancers(144;7.7e-09)|LUSC - Lung squamous cell carcinoma(224;0.034)|Lung(119;0.0375)		AGGTGGCTCCGTTCAGACAGC	0.517000													22	57					0	0	1	0	0
RGN	9104	broad.mit.edu	37	X	46951083	46951083	+	Missense_Mutation	SNP	G	G	T	rs147490967	byFrequency	TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chrX:46951083G>T	ENST00000397180.1	+	6	1538	c.569G>T	c.(568-570)cGc>cTc	p.R190L	RGN_ENST00000352078.4_Missense_Mutation_p.R190L|RGN_ENST00000336169.3_Missense_Mutation_p.R190L|RGN_ENST00000457380.1_Missense_Mutation_p.R118L	NM_152869.2	NP_690608.1	Q15493	RGN_HUMAN	regucalcin	190					cellular calcium ion homeostasis|positive regulation of ATPase activity|regulation of calcium-mediated signaling	cytoplasm|nucleus	calcium ion binding|enzyme regulator activity|gluconolactonase activity|zinc ion binding			breast(1)|central_nervous_system(2)|endometrium(1)|large_intestine(1)|lung(2)|skin(1)|urinary_tract(1)	9						ATAGCCAACCGCAGAAGTGTT	0.428000													3	21					0.004672	0.0049056	1	1	0
CD300C	10871	broad.mit.edu	37	17	72539104	72539104	+	Missense_Mutation	SNP	G	G	T			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr17:72539104G>T	ENST00000330793.1	-	3	783	c.423C>A	c.(421-423)agC>agA	p.S141R		NM_006678.3	NP_006669.1	Q08708	CLM6_HUMAN	CD300c molecule	141	Pro-rich.				cellular defense response	integral to plasma membrane	transmembrane receptor activity			endometrium(2)|kidney(1)|large_intestine(4)|lung(11)|skin(2)|upper_aerodigestive_tract(1)	21						AGCTCTGGGGGCTGGAGGCTG	0.607000													7	29					0.00448238	0.0049056	1	1	0
TTC17	55761	broad.mit.edu	37	11	43471655	43471655	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr11:43471655C>T	ENST00000039989.4	+	20	2824	c.2810C>T	c.(2809-2811)gCc>gTc	p.A937V		NM_018259.5	NP_060729.2	Q96AE7	TTC17_HUMAN	tetratricopeptide repeat domain 17	937							binding			breast(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(7)|lung(27)|ovary(5)|prostate(3)|skin(3)	53						ATAGATTTTGCCACCCCTATA	0.473000													4	93					0	0	1	0	0
AHNAK2	113146	broad.mit.edu	37	14	105409977	105409977	+	Silent	SNP	G	G	A			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr14:105409977G>A	ENST00000333244.5	-	7	11930	c.11811C>T	c.(11809-11811)gaC>gaT	p.D3937D	AHNAK2_ENST00000557457.1_Intron	NM_138420.2	NP_612429.2	Q8IVF2	AHNK2_HUMAN	AHNAK nucleoprotein 2	3937						nucleus				cervix(4)|endometrium(4)|large_intestine(3)|lung(14)|ovary(2)|prostate(2)|skin(1)|stomach(3)	33		all_cancers(154;0.115)|Melanoma(154;0.155)|all_epithelial(191;0.183)	all cancers(16;0.000479)|OV - Ovarian serous cystadenocarcinoma(23;0.00659)|Epithelial(46;0.0151)|GBM - Glioblastoma multiforme(11;0.116)			GGGCCTCGACGTCCACCTCCA	0.597000													6	289					0	0	1	0	0
TUBB8P7	0	broad.mit.edu	37	16	90161618	90161618	+	RNA	SNP	C	C	T	rs13338202	by1000genomes	TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr16:90161618C>T	ENST00000564451.1	+	0	971				TUBB8P7_ENST00000567960.1_RNA														p.D118D(2)									CAGTGATGGACGTTGTCAGAA	0.607000													8	31					0	0	1	0	0
MYADM	91663	broad.mit.edu	37	19	54377573	54377573	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr19:54377573G>A	ENST00000391769.2	+	3	1070	c.790G>A	c.(790-792)Gat>Aat	p.D264N	MYADM_ENST00000336967.3_Missense_Mutation_p.D264N|MYADM_ENST00000391768.2_Missense_Mutation_p.D264N|MYADM_ENST00000391770.4_Missense_Mutation_p.D264N|MYADM_ENST00000391771.1_Missense_Mutation_p.D264N	NM_001020821.1	NP_001018657.1	Q96S97	MYADM_HUMAN	myeloid-associated differentiation marker	264	MARVEL 2.					integral to membrane		p.D264Y(1)		central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(4)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)	12	Ovarian(34;0.19)			GBM - Glioblastoma multiforme(134;0.0488)		CTACCAGTTCGATGAGAAGTA	0.637000													3	42					0	0	1	0	0
RNF17	56163	broad.mit.edu	37	13	25451163	25451163	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr13:25451163C>T	ENST00000255324.5	+	34	4664	c.4612C>T	c.(4612-4614)Cgg>Tgg	p.R1538W	RNF17_ENST00000381921.1_Missense_Mutation_p.R1496W|RNF17_ENST00000339524.3_Missense_Mutation_p.R548W	NM_001184993.1|NM_031277.2	NP_001171922.1|NP_112567.2	Q9BXT8	RNF17_HUMAN	ring finger protein 17	1538	Tudor 4.				multicellular organismal development	cytoplasm|nucleus	hydrolase activity, acting on ester bonds|nucleic acid binding|zinc ion binding			NS(1)|breast(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(15)|ovary(1)|prostate(3)|skin(6)	36		Lung SC(185;0.0225)|Breast(139;0.077)		all cancers(112;0.0114)|OV - Ovarian serous cystadenocarcinoma(117;0.0311)|Epithelial(112;0.0524)		TCATCTTATGCGGTATCCAGC	0.403000													4	72					0	0	1	0	0
RPS27L	51065	broad.mit.edu	37	15	63447932	63447932	+	Splice_Site	SNP	T	T	C			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr15:63447932T>C	ENST00000330964.5	-	3	512		c.e3-2		RPS27L_ENST00000455271.1_Splice_Site|RPS27L_ENST00000411926.1_Splice_Site|RPS27L_ENST00000439025.1_Splice_Site|RPS27L_ENST00000462430.1_Splice_Site	NM_015920.3	NP_057004.1	Q71UM5	RS27L_HUMAN	ribosomal protein S27-like						DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA repair|mitotic cell cycle G1/S transition DNA damage checkpoint|positive regulation of anti-apoptosis|translation	nucleus|ribosome	caspase activator activity|metal ion binding|structural constituent of ribosome|translation activator activity			large_intestine(1)	1						TGTAGCAACCTAAAAAAAAAA	0.398000													4	17					0	0	1	0	0
JARID2	3720	broad.mit.edu	37	6	15501192	15501192	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr6:15501192G>A	ENST00000341776.2	+	8	2244	c.2000G>A	c.(1999-2001)gGc>gAc	p.G667D	JARID2_ENST00000397311.3_Missense_Mutation_p.G495D|JARID2_ENST00000541660.1_Missense_Mutation_p.G629D	NM_004973.3	NP_004964.2	Q92833	JARD2_HUMAN	jumonji, AT rich interactive domain 2	667	ARID.				central nervous system development|chromatin modification|negative regulation of histone methylation|positive regulation of histone H3-K9 methylation|stem cell differentiation|transcription, DNA-dependent		chromatin binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(10)|kidney(2)|large_intestine(15)|lung(19)|ovary(3)|pancreas(1)|prostate(5)|stomach(1)	59	Breast(50;0.0142)|Ovarian(93;0.103)	all_hematologic(90;0.00612)				GAGATGGGCGGCATGCAGCAA	0.562000													4	124					0	0	1	0	0
ARID3A	1820	broad.mit.edu	37	19	971939	971939	+	Silent	SNP	C	C	T			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr19:971939C>T	ENST00000263620.3	+	9	1983	c.1656C>T	c.(1654-1656)ggC>ggT	p.G552G		NM_005224.2	NP_005215.1	Q99856	ARI3A_HUMAN	AT rich interactive domain 3A (BRIGHT-like)	552	Gly-rich.|Important for cytoplasmic localization (By similarity).					cytoplasm|nucleus	DNA binding|sequence-specific DNA binding transcription factor activity	p.G552G(1)		breast(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(1)|lung(2)|ovary(1)	10		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;1.04e-05)|all_lung(49;1.53e-05)|Breast(49;9.42e-05)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		AAGGAggcggcggcggcggcg	0.657000													3	37					0	0	1	0	0
CACNA1D	776	broad.mit.edu	37	3	53757871	53757879	+	In_Frame_Del	DEL	TCCATCGCT	TCCATCGCT	-	rs139269186		TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr3:53757871_53757879delTCCATCGCT	ENST00000288139.3	+	15	2123_2131	c.2005_2013delTCCATCGCT	c.(2005-2013)del	p.SIA669del	CACNA1D_ENST00000422281.2_In_Frame_Del_p.SIA649del|CACNA1D_ENST00000350061.5_In_Frame_Del_p.SIA649del	NM_000720.2	NP_000711.1	Q01668	CAC1D_HUMAN	calcium channel, voltage-dependent, L type, alpha 1D subunit	649					axon guidance|energy reserve metabolic process|regulation of insulin secretion	voltage-gated calcium channel complex	voltage-gated calcium channel activity			breast(3)|central_nervous_system(9)|cervix(2)|endometrium(11)|kidney(7)|large_intestine(13)|liver(1)|lung(29)|ovary(6)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	90				BRCA - Breast invasive adenocarcinoma(193;0.00029)|KIRC - Kidney renal clear cell carcinoma(284;0.0145)|Kidney(284;0.0175)|OV - Ovarian serous cystadenocarcinoma(275;0.0613)	Verapamil(DB00661)	CTCCATGAAGTCCATCGCTTCGCTGTTGC	0.455													19	113	---	---	---	---					
DGKB	1607	broad.mit.edu	37	7	14652983	14652983	+	Frame_Shift_Del	DEL	C	C	-			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr7:14652983delC	ENST00000403951.2	-	16	1762	c.1343delG	c.(1342-1344)gtfs	p.G449fs	DGKB_ENST00000403963.1_5'UTR|DGKB_ENST00000407950.1_Frame_Shift_Del_p.G441fs|DGKB_ENST00000406247.3_Frame_Shift_Del_p.G449fs|DGKB_ENST00000399322.3_Frame_Shift_Del_p.G449fs|DGKB_ENST00000258767.5_Frame_Shift_Del_p.G449fs|DGKB_ENST00000444700.2_Frame_Shift_Del_p.G430fs|DGKB_ENST00000402815.1_Frame_Shift_Del_p.G448fs			Q9Y6T7	DGKB_HUMAN	diacylglycerol kinase, beta 90kDa	449	DAGKc.				activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|intracellular signal transduction|platelet activation	cytoplasm|plasma membrane	ATP binding|calcium ion binding|diacylglycerol kinase activity|protein binding			NS(1)|breast(4)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(11)|liver(1)|lung(34)|ovary(4)|prostate(4)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	72					Phosphatidylserine(DB00144)	TTGTTTTCCACCACTTTTGGG	0.318													2	4	---	---	---	---					
PABPC1	26986	broad.mit.edu	37	8	101730036	101730037	+	Frame_Shift_Ins	INS	-	-	C			TCGA-WB-A817-01A-11D-A35I-08	TCGA-WB-A817-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f838433f-27eb-4de5-b188-19bec45b6297	c8459b8e-10f3-4a0d-8988-47ea061d3d49	g.chr8:101730036_101730037insC	ENST00000318607.5	-	3	1595_1596	c.467_468insG	c.(466-468)gaafs	p.E156fs	PABPC1_ENST00000519004.1_Frame_Shift_Ins_p.E111fs|PABPC1_ENST00000522387.1_Frame_Shift_Ins_p.E124fs	NM_002568.3	NP_002559.2	P11940	PABP1_HUMAN	poly(A) binding protein, cytoplasmic 1	156	RRM 2.				mRNA polyadenylation|mRNA stabilization|negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|nuclear-transcribed mRNA poly(A) tail shortening|translation	catalytic step 2 spliceosome|cytosol	nucleotide binding|poly(A) RNA binding|protein C-terminus binding|translation activator activity			breast(2)|endometrium(4)|kidney(15)|large_intestine(4)|lung(13)|prostate(1)|skin(1)	40	all_cancers(14;6.8e-05)|all_epithelial(15;3.16e-07)|Lung NSC(17;0.000453)|all_lung(17;0.00125)		Epithelial(11;6.37e-11)|all cancers(13;1.11e-08)|OV - Ovarian serous cystadenocarcinoma(57;3.91e-05)|STAD - Stomach adenocarcinoma(118;0.206)			CATTCATTTTTTCAATAGCTCT	0.337													7	59	---	---	---	---					
