Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
QPCT	25797	broad.mit.edu	37	2	37594434	37594434	+	Silent	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr2:37594434G>A	ENST00000338415.3	+	4	764	c.606G>A	c.(604-606)gaG>gaA	p.E202E	QPCT_ENST00000537448.1_Silent_p.E153E	NM_012413.3	NP_036545.1	Q16769	QPCT_HUMAN	glutaminyl-peptide cyclotransferase	202					peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase|proteolysis	extracellular region	acyltransferase activity|glutaminyl-peptide cyclotransferase activity|peptidase activity|zinc ion binding			central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(4)|lung(3)|prostate(1)|stomach(2)	17		Ovarian(717;0.051)|all_hematologic(82;0.21)				ATGGTGAAGAGGCTTTTCTTC	0.458000													22	73					0	0	1	0	0
PVALB	5816	broad.mit.edu	37	22	37211274	37211274	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr22:37211274C>T	ENST00000216200.5	-	3	122	c.67G>A	c.(67-69)Gac>Aac	p.D23N	PVALB_ENST00000417718.2_Missense_Mutation_p.D23N|PVALB_ENST00000404171.1_5'UTR	NM_002854.2	NP_002845.1	P20472	PRVA_HUMAN	parvalbumin	23							calcium ion binding			large_intestine(1)|lung(1)|skin(1)	3						TCGAAGGAGTCGGTAGCTGTG	0.507000													11	16					0	0	1	0	0
U2AF1	7307	broad.mit.edu	37	21	44521486	44521486	+	Translation_Start_Site	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr21:44521486G>A	ENST00000398137.1	-	0	272				U2AF1_ENST00000291552.4_Intron|U2AF1_ENST00000380276.2_Silent_p.D63D|U2AF1_ENST00000486519.1_Intron|U2AF1_ENST00000459639.1_Intron	NM_001025204.1	NP_001020375.1	Q01081	U2AF1_HUMAN	U2 small nuclear RNA auxiliary factor 1						mRNA 3'-end processing|mRNA export from nucleus|termination of RNA polymerase II transcription	Cajal body|catalytic step 2 spliceosome|nuclear speck	nucleotide binding|RNA binding|zinc ion binding			breast(1)|central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(111)|large_intestine(2)|lung(7)|prostate(2)|skin(1)	126						AGTGTGAGCCGTCAGCCGTCT	0.413000			Mis		"""CLL, MDS"""								4	286					0	0	1	0	0
TTN	7273	broad.mit.edu	37	2	179495667	179495667	+	Missense_Mutation	SNP	C	C	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr2:179495667C>A	ENST00000589042.1	-	238	44242	c.44018G>T	c.(44017-44019)cGg>cTg	p.R14673L	TTN_ENST00000460472.2_Missense_Mutation_p.R5608L|TTN-AS1_ENST00000585451.1_RNA|TTN-AS1_ENST00000589487.1_RNA|TTN-AS1_ENST00000589830.1_RNA|TTN-AS1_ENST00000592630.1_RNA|TTN_ENST00000591111.1_Missense_Mutation_p.R13032L|TTN-AS1_ENST00000590807.1_RNA|TTN_ENST00000342992.6_Missense_Mutation_p.R12105L|TTN_ENST00000342175.6_Missense_Mutation_p.R5800L|TTN_ENST00000359218.5_Missense_Mutation_p.R5733L|TTN-AS1_ENST00000589907.1_RNA	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	13032	Ig-like 96.						ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			TTTAATTTCCCGATCTAGAAA	0.473000													3	28					0.115264	0.115264	1	1	0
DPP9	91039	broad.mit.edu	37	19	4704312	4704312	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr19:4704312G>A	ENST00000262960.9	-	6	708	c.431C>T	c.(430-432)aCg>aTg	p.T144M	DPP9_ENST00000597849.1_Missense_Mutation_p.T144M|DPP9_ENST00000598800.1_Missense_Mutation_p.T115M|DPP9_ENST00000594671.1_Missense_Mutation_p.T115M	NM_139159.4	NP_631898.3	Q86TI2	DPP9_HUMAN	dipeptidyl-peptidase 9	115					proteolysis	cytosol|membrane	aminopeptidase activity|serine-type peptidase activity			cervix(2)|endometrium(3)|kidney(3)|large_intestine(2)|lung(6)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	20		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.00884)		ATGGTGGGGCGTGGCCTGGAA	0.647000													28	59					0	0	1	0	0
TATDN2	9797	broad.mit.edu	37	3	10318140	10318140	+	Silent	SNP	A	A	G			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr3:10318140A>G	ENST00000287652.4	+	5	2980	c.1929A>G	c.(1927-1929)aaA>aaG	p.K643K	TATDN2_ENST00000448281.2_Silent_p.K643K|TATDN2_ENST00000496355.1_3'UTR|RP11-438J1.1_ENST00000450534.1_3'UTR	NM_014760.3	NP_055575.3	Q93075	TATD2_HUMAN	TatD DNase domain containing 2	643						nucleus	endodeoxyribonuclease activity, producing 5'-phosphomonoesters|metal ion binding			autonomic_ganglia(1)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(8)|lung(9)|pancreas(2)|prostate(1)|stomach(2)	28						AAATCATGAAAAAGTTTGTGC	0.468000													4	79					0	0	1	0	0
PMFBP1	83449	broad.mit.edu	37	16	72188312	72188312	+	Missense_Mutation	SNP	T	T	C			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr16:72188312T>C	ENST00000537465.1	-	4	370	c.212A>G	c.(211-213)gAa>gGa	p.E71G	PMFBP1_ENST00000355636.6_5'UTR|PMFBP1_ENST00000543746.1_5'UTR|PMFBP1_ENST00000237353.10_Missense_Mutation_p.E71G			Q8TBY8	PMFBP_HUMAN	polyamine modulated factor 1 binding protein 1	71										NS(1)|breast(3)|endometrium(1)|kidney(2)|large_intestine(7)|lung(25)|ovary(2)|skin(3)|urinary_tract(1)	45		Ovarian(137;0.179)				GGACCCAAATTCCACCTCTGA	0.433000													4	111					0	0	1	0	0
BEND5	79656	broad.mit.edu	37	1	49224701	49224701	+	Missense_Mutation	SNP	G	G	A	rs150209705	by1000genomes	TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr1:49224701G>A	ENST00000371833.3	-	3	702	c.616C>T	c.(616-618)Cgg>Tgg	p.R206W	BEND5_ENST00000476096.1_5'UTR|AGBL4_ENST00000371839.1_Intron|AGBL4_ENST00000371838.1_Intron	NM_024603.2	NP_078879.2	Q7L4P6	BEND5_HUMAN	BEN domain containing 5	206										large_intestine(5)|lung(2)|skin(1)	8						CTCCGAGTCCGCTCCAGCTCC	0.587000													4	69					0	0	1	0	0
RP9	6100	broad.mit.edu	37	7	33136944	33136944	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr7:33136944G>A	ENST00000297157.3	-	4	361	c.344C>T	c.(343-345)aCg>aTg	p.T115M		NM_203288.1	NP_976033.1	Q8TA86	RP9_HUMAN	retinitis pigmentosa 9 (autosomal dominant)	115	PIM1-binding (By similarity).				RNA splicing	nucleus	nucleic acid binding|protein binding|zinc ion binding			large_intestine(3)|lung(3)|urinary_tract(1)	7			GBM - Glioblastoma multiforme(11;0.0403)			TTTGTCACCCGTTCGGTGACC	0.378000													23	45					0	0	1	0	0
MUC16	94025	broad.mit.edu	37	19	9060544	9060544	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr19:9060544G>A	ENST00000397910.4	-	3	27105	c.26902C>T	c.(26902-26904)Cca>Tca	p.P8968S		NM_024690.2	NP_078966.2	Q8WXI7	MUC16_HUMAN	mucin 16, cell surface associated	8970	Ser-rich.|Thr-rich.				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding	p.P8968A(2)|p.P4601A(1)		NS(9)|autonomic_ganglia(1)|breast(26)|central_nervous_system(11)|cervix(1)|endometrium(46)|haematopoietic_and_lymphoid_tissue(5)|kidney(35)|large_intestine(91)|liver(1)|lung(278)|ovary(17)|pancreas(2)|prostate(17)|skin(18)|soft_tissue(1)|stomach(8)|upper_aerodigestive_tract(16)|urinary_tract(7)	590						GTGACCACTGGAGATGTCACT	0.463000													12	110					0	0	1	0	0
PRSS27	83886	broad.mit.edu	37	16	2763562	2763562	+	Missense_Mutation	SNP	C	C	T			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr16:2763562C>T	ENST00000302641.3	-	5	700	c.646G>A	c.(646-648)Ggc>Agc	p.G216S		NM_031948.3	NP_114154.1	Q9BQR3	PRS27_HUMAN	protease, serine 27	216	Peptidase S1.				proteolysis	extracellular region	serine-type endopeptidase activity			breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(2)|ovary(1)	8						TCCTCGAAGCCGGCGCACAGC	0.582000													5	119					0	0	1	0	0
KLC4	89953	broad.mit.edu	37	6	43034200	43034200	+	Missense_Mutation	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr6:43034200G>A	ENST00000394056.2	+	6	1223	c.728G>A	c.(727-729)cGc>cAc	p.R243H	KLC4_ENST00000259708.3_Missense_Mutation_p.R261H|KLC4_ENST00000458460.2_Missense_Mutation_p.R243H|KLC4_ENST00000453940.2_Missense_Mutation_p.R166H|KLC4_ENST00000394058.1_Missense_Mutation_p.R243H|KLC4_ENST00000347162.5_Missense_Mutation_p.R243H|KLC4_ENST00000479388.1_Missense_Mutation_p.R243H			Q9NSK0	KLC4_HUMAN	kinesin light chain 4	243						cytoplasm|kinesin complex|microtubule	microtubule motor activity|protein binding			endometrium(2)|large_intestine(7)|lung(5)|ovary(1)|pancreas(1)|skin(3)|urinary_tract(4)	23			all cancers(41;0.00169)|Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|OV - Ovarian serous cystadenocarcinoma(102;0.0376)|KIRC - Kidney renal clear cell carcinoma(2;0.0453)			GACCTGGAGCGCACATCAGGC	0.597000													3	44					0	0	1	0	0
PTPN14	5784	broad.mit.edu	37	1	214537876	214537876	+	Missense_Mutation	SNP	G	G	C			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr1:214537876G>C	ENST00000366956.5	-	18	3608	c.3414C>G	c.(3412-3414)atC>atG	p.I1138M	PTPN14_ENST00000543945.1_3'UTR	NM_005401.4	NP_005392.2	Q15678	PTN14_HUMAN	protein tyrosine phosphatase, non-receptor type 14	1138	Tyrosine-protein phosphatase.				lymphangiogenesis	cytoplasm|cytoskeleton	protein tyrosine phosphatase activity|receptor tyrosine kinase binding			NS(2)|breast(3)|cervix(1)|endometrium(7)|kidney(2)|large_intestine(9)|liver(3)|lung(21)|ovary(1)|pancreas(1)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	58				OV - Ovarian serous cystadenocarcinoma(81;0.00181)|all cancers(67;0.00194)|Epithelial(68;0.0157)|GBM - Glioblastoma multiforme(131;0.155)		CCAAGCAGTAGATCATCAGCT	0.567000													10	46					0	0	1	0	0
AGAP11	119385	broad.mit.edu	37	10	88769022	88769022	+	RNA	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr10:88769022G>A	ENST00000444431.1	+	0	3622				RP11-96C23.5_ENST00000433214.2_RNA|RP11-96C23.14_ENST00000444180.3_RNA			Q8TF27	AGA11_HUMAN	ankyrin repeat and GTPase domain Arf GTPase activating protein 11						regulation of ARF GTPase activity		ARF GTPase activator activity|zinc ion binding										CAAAACATGCGTGGGAACTCC	0.552000													6	211					0	0	1	0	0
SHPRH	257218	broad.mit.edu	37	6	146262866	146262866	+	Missense_Mutation	SNP	G	G	T			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr6:146262866G>T	ENST00000367503.3	-	10	2781	c.2383C>A	c.(2383-2385)Cta>Ata	p.L795I	SHPRH_ENST00000275233.7_Missense_Mutation_p.L795I|SHPRH_ENST00000367505.2_Missense_Mutation_p.L795I|SHPRH_ENST00000438092.2_Missense_Mutation_p.L795I	NM_001042683.2	NP_001036148.2	Q149N8	SHPRH_HUMAN	SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase	795	Helicase ATP-binding; second part.				DNA repair|nucleosome assembly	nucleosome|nucleus	ATP binding|DNA binding|helicase activity|ligase activity|zinc ion binding			breast(2)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(15)|lung(33)|ovary(3)|pancreas(2)|prostate(7)|skin(1)|urinary_tract(1)	79		Ovarian(120;0.0365)		OV - Ovarian serous cystadenocarcinoma(155;1.47e-07)|GBM - Glioblastoma multiforme(68;0.0124)		TGGTTCCGTAGGCGACGCCCA	0.483000													5	39					0.014758	0.0158512	1	1	0
UBC	7316	broad.mit.edu	37	12	125397415	125397415	+	Silent	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr12:125397415G>A	ENST00000536769.1	-	1	2479	c.903C>T	c.(901-903)ctC>ctT	p.L301L	UBC_ENST00000546120.1_Silent_p.L225L|UBC_ENST00000538617.1_Intron|UBC_ENST00000339647.5_Silent_p.L301L			P0CG48	UBC_HUMAN	ubiquitin C	301	Ubiquitin-like 4.				activation of MAPK activity|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|anti-apoptosis|apoptosis|cellular membrane organization|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA repair|endosome transport|epidermal growth factor receptor signaling pathway|G1/S transition of mitotic cell cycle|I-kappaB kinase/NF-kappaB cascade|induction of apoptosis by extracellular signals|innate immune response|JNK cascade|M/G1 transition of mitotic cell cycle|mRNA metabolic process|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of type I interferon production|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|nerve growth factor receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|S phase of mitotic cell cycle|stress-activated MAPK cascade|T cell receptor signaling pathway|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway|viral reproduction	cytosol|endocytic vesicle membrane|endosome membrane|nucleoplasm|plasma membrane	protein binding			breast(3)|endometrium(4)|kidney(4)|large_intestine(2)|lung(13)|ovary(3)|prostate(4)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;6.17e-05)|Epithelial(86;0.000207)|all cancers(50;0.00308)		TCCCACCTCTGAGACGGAGCA	0.532000													4	121					0	0	1	0	0
MAN1B1	11253	broad.mit.edu	37	9	140001177	140001177	+	Silent	SNP	C	C	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr9:140001177C>A	ENST00000371589.4	+	10	1555	c.1482C>A	c.(1480-1482)gtC>gtA	p.V494V	MAN1B1_ENST00000474902.1_Silent_p.V197V|MAN1B1_ENST00000540391.1_3'UTR	NM_016219.4	NP_057303.2	Q9UKM7	MA1B1_HUMAN	mannosidase, alpha, class 1B, member 1	494					oligosaccharide metabolic process|post-translational protein modification|protein folding|protein N-linked glycosylation via asparagine	endoplasmic reticulum membrane|endoplasmic reticulum quality control compartment|integral to membrane	alpha-mannosidase activity|calcium ion binding|mannosyl-oligosaccharide 1,2-alpha-mannosidase activity			autonomic_ganglia(1)|central_nervous_system(2)|kidney(1)|large_intestine(2)|liver(2)|lung(4)|ovary(2)	14	all_cancers(76;0.0926)	Myeloproliferative disorder(178;0.0511)	STAD - Stomach adenocarcinoma(284;0.0878)	OV - Ovarian serous cystadenocarcinoma(145;3.08e-05)|Epithelial(140;0.000513)		TCGAGGGTGTCAGAACGCACC	0.627000													3	23					0.115264	0.115264	1	1	0
EXTL2	2135	broad.mit.edu	37	1	101339869	101339869	+	Missense_Mutation	SNP	A	A	G			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr1:101339869A>G	ENST00000370114.3	-	5	2058	c.622T>C	c.(622-624)Tac>Cac	p.Y208H	EXTL2_ENST00000535414.1_Missense_Mutation_p.Y195H|EXTL2_ENST00000370113.3_Missense_Mutation_p.Y208H	NM_001033025.2|NM_001261440.1	NP_001028197.1|NP_001248369.1	Q9UBQ6	EXTL2_HUMAN	exostosin-like glycosyltransferase 2	208					N-acetylglucosamine metabolic process|UDP-N-acetylgalactosamine metabolic process	extracellular region|integral to membrane|intrinsic to endoplasmic reticulum membrane	alpha-1,4-N-acetylgalactosaminyltransferase activity|glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity|metal ion binding			haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|lung(4)|skin(1)|urinary_tract(1)	14		all_epithelial(167;2.48e-06)|all_lung(203;0.000414)|Lung NSC(277;0.000946)		Epithelial(280;0.0425)|all cancers(265;0.0628)|COAD - Colon adenocarcinoma(174;0.148)|Colorectal(144;0.167)|Lung(183;0.195)		ACCATAGAGTACTGGTCACCA	0.413000													3	46					0	0	1	0	0
NFIC	4782	broad.mit.edu	37	19	3382111	3382111	+	Silent	SNP	G	G	A			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr19:3382111G>A	ENST00000589123.1	+	2	525	c.405G>A	c.(403-405)gaG>gaA	p.E135E	NFIC_ENST00000586919.1_Silent_p.E135E|NFIC_ENST00000346156.5_Silent_p.E135E|NFIC_ENST00000590282.1_Silent_p.E144E|NFIC_ENST00000443272.2_Silent_p.E144E|NFIC_ENST00000341919.3_Silent_p.E144E|NFIC_ENST00000395111.3_Silent_p.E135E	NM_001245005.1|NM_205843.2	NP_001231934.1|NP_995315.1	P08651	NFIC_HUMAN	nuclear factor I/C (CCAAT-binding transcription factor)	144					DNA replication|negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity			NS(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(10)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	21		Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;7.8e-05)|Epithelial(107;2.94e-108)|BRCA - Breast invasive adenocarcinoma(158;0.00154)|STAD - Stomach adenocarcinoma(1328;0.191)		TCCCGCTGGAGAGCACCGACG	0.667000													28	83					0	0	1	0	0
H1F0	3005	broad.mit.edu	37	22	38201891	38201891	+	Missense_Mutation	SNP	A	A	G			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr22:38201891A>G	ENST00000340857.2	+	1	778	c.340A>G	c.(340-342)Atc>Gtc	p.I114V		NM_005318.3	NP_005309.1	P07305	H10_HUMAN	H1 histone family, member 0	114					DNA fragmentation involved in apoptotic nuclear change|nucleosome assembly	actin cytoskeleton|Golgi apparatus|nucleoplasm|nucleosome	DNA binding			cervix(1)|endometrium(1)|kidney(2)|prostate(2)|urinary_tract(1)	7	Melanoma(58;0.045)					CAAGAAGGAAATCAAGAAGGT	0.572000													10	26					0	0	1	0	0
THSD7B	80731	broad.mit.edu	37	2	138413157	138413157	+	Silent	SNP	C	C	T			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr2:138413157C>T	ENST00000409968.1	+	22	4210	c.4032C>T	c.(4030-4032)gtC>gtT	p.V1344V	THSD7B_ENST00000543459.1_Intron|THSD7B_ENST00000413152.2_Silent_p.V1316V|THSD7B_ENST00000272643.3_Silent_p.V1347V					thrombospondin, type I, domain containing 7B											NS(3)|breast(3)|central_nervous_system(2)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(14)|lung(57)|ovary(4)|pancreas(3)|prostate(11)|skin(4)|stomach(3)|upper_aerodigestive_tract(5)|urinary_tract(3)	134				BRCA - Breast invasive adenocarcinoma(221;0.19)		CTGGACGTGTCGAGGATGCAC	0.537000													4	6					0	0	1	0	0
TRAV9-2	0	broad.mit.edu	37	14	22409533	22409539	+	RNA	DEL	CTCTCTC	CTCTCTC	-	rs57759840		TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr14:22409533_22409539delCTCTCTC	ENST00000390441.2	+	0	102																											ctctctctctctctctctTTTTTTTTT	0.415													5	3	---	---	---	---					
LMAN1L	79748	broad.mit.edu	37	15	75113473	75113474	+	Frame_Shift_Del	DEL	CT	CT	-			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr15:75113473_75113474delCT	ENST00000309664.5	+	9	1104_1105	c.965_966delCT	c.(964-966)gfs	p.A322fs	RP11-414J4.2_ENST00000564823.1_RNA|LMAN1L_ENST00000379709.3_Frame_Shift_Del_p.A310fs	NM_021819.2	NP_068591.2	Q9HAT1	LMA1L_HUMAN	lectin, mannose-binding, 1 like	322						ER-Golgi intermediate compartment membrane|integral to membrane	sugar binding			NS(2)|breast(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(8)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	19						ATCCTGCAGGCTCTGCGGGGTC	0.653													2	4	---	---	---	---					
ABCA17P	0	broad.mit.edu	37	16	2475097	2475098	+	RNA	DEL	TC	TC	-			TCGA-WB-A820-01A-11D-A35I-08	TCGA-WB-A820-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f618a4dd-f602-4499-ac44-f8bcd60ea8ce	858c3e31-1211-4c37-bb03-991a561f0860	g.chr16:2475097_2475098delTC	ENST00000469908.1	+	0	3047					NR_003574.1																						GGTAActctgtctctctctctc	0.559													2	4	---	---	---	---					
