Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample
TNN	63923	broad.mit.edu	37	1	175049544	175049544	+	Missense_Mutation	SNP	C	C	T	rs140077325		TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr1:175049544C>T	ENST00000239462.4	+	4	1143	c.1030C>T	c.(1030-1032)Cat>Tat	p.H344Y		NM_022093.1	NP_071376.1	Q9UQP3	TENN_HUMAN	tenascin N	344	Fibronectin type-III 1.				cell growth|cell migration|signal transduction	extracellular space|proteinaceous extracellular matrix				NS(1)|central_nervous_system(2)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(29)|liver(1)|lung(81)|ovary(5)|prostate(6)|skin(5)|stomach(4)|upper_aerodigestive_tract(3)|urinary_tract(3)	156		Breast(1374;0.000962)		KIRC - Kidney renal clear cell carcinoma(1967;0.00198)		CAGCCCACAGCATCTACTTGC	0.507													4	53	---	---	---	---
FUNDC2P2	388965	broad.mit.edu	37	2	84517924	84517924	+	RNA	SNP	G	G	A			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr2:84517924G>A	ENST00000331369.5	+	0	118																											GTGTGTCCTCGCAAGACTAGC	0.587													5	13	---	---	---	---
RGPD4	285190	broad.mit.edu	37	2	108487522	108487522	+	Missense_Mutation	SNP	T	T	C			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr2:108487522T>C	ENST00000408999.3	+	20	3139	c.3062T>C	c.(3061-3063)tTt>tCt	p.F1021S	RGPD4_ENST00000354986.4_Missense_Mutation_p.F1021S	NM_182588.2	NP_872394.2	Q7Z3J3	RGPD4_HUMAN	RANBP2-like and GRIP domain containing 4	1021					intracellular transport		binding			breast(1)|endometrium(7)|kidney(4)|lung(23)|pancreas(1)|prostate(1)|skin(3)|urinary_tract(3)	43						TCCGGTGACTTTGAGAAAGAT	0.383													4	264	---	---	---	---
MAP2	4133	broad.mit.edu	37	2	210588329	210588329	+	Nonsense_Mutation	SNP	T	T	A			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr2:210588329T>A	ENST00000199940.6	+	12	1627	c.1187T>A	c.(1186-1188)tTa>tAa	p.L396*	MAP2_ENST00000392194.1_Intron|MAP2_ENST00000447185.1_Intron|MAP2_ENST00000361559.4_Intron|MAP2_ENST00000475600.1_3'UTR|MAP2_ENST00000360351.4_Intron	NM_001039538.1	NP_001034627.1	P11137	MAP2_HUMAN	microtubule-associated protein 2	1674					central nervous system neuron development|dendrite morphogenesis|negative regulation of microtubule depolymerization	cytoplasm|microtubule|microtubule associated complex	beta-dystroglycan binding|calmodulin binding|structural molecule activity			breast(7)|central_nervous_system(1)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(36)|liver(2)|lung(42)|ovary(11)|pancreas(2)|prostate(2)|skin(2)|stomach(4)|upper_aerodigestive_tract(4)|urinary_tract(1)	124		Hepatocellular(293;0.137)|Lung NSC(271;0.163)|Renal(323;0.202)		UCEC - Uterine corpus endometrioid carcinoma (47;6.64e-05)|Epithelial(149;3.12e-100)|all cancers(144;6.88e-91)|Lung(261;0.0624)|LUSC - Lung squamous cell carcinoma(261;0.0662)|STAD - Stomach adenocarcinoma(1183;0.18)	Estramustine(DB01196)	GTTAGGATTTTAAACAAGAAG	0.408													11	28	---	---	---	---
CHL1	10752	broad.mit.edu	37	3	419627	419627	+	Splice_Site	SNP	T	T	C			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr3:419627T>C	ENST00000256509.2	+	16	2518		c.e16+2		CHL1-AS1_ENST00000417612.1_RNA|CHL1_ENST00000397491.2_Splice_Site	NM_001253387.1|NM_001253388.1|NM_006614.3	NP_001240316.1|NP_001240317.1|NP_006605.2	O00533	CHL1_HUMAN	cell adhesion molecule L1-like						axon guidance|cell adhesion|signal transduction	integral to membrane|plasma membrane|proteinaceous extracellular matrix				NS(1)|central_nervous_system(5)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(25)|lung(31)|ovary(1)|prostate(4)|skin(10)|stomach(1)	93		all_cancers(2;1.14e-06)|all_epithelial(2;0.00367)|all_lung(1;0.061)|Lung NSC(2;0.201)		Epithelial(13;5.36e-06)|all cancers(10;1.4e-05)|OV - Ovarian serous cystadenocarcinoma(96;0.00323)|COAD - Colon adenocarcinoma(1;0.00925)|Colorectal(20;0.0198)		CTGTTCTTGGTAAGTGCACTA	0.393													3	63	---	---	---	---
ANK2	287	broad.mit.edu	37	4	114278436	114278436	+	Nonsense_Mutation	SNP	A	A	T			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr4:114278436A>T	ENST00000357077.4	+	38	8715	c.8662A>T	c.(8662-8664)Aag>Tag	p.K2888*	ANK2_ENST00000394537.3_Intron|ANK2_ENST00000510275.2_Intron|ANK2_ENST00000264366.6_Nonsense_Mutation_p.K2855*|ANK2_ENST00000506722.1_Intron|ANK2_ENST00000509550.1_Intron	NM_001148.4	NP_001139.3	Q01484	ANK2_HUMAN	ankyrin 2, neuronal	2855					axon guidance|signal transduction	apical plasma membrane|basolateral plasma membrane|cytoskeleton|cytosol|sarcomere	protein binding			NS(1)|biliary_tract(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(54)|liver(2)|lung(112)|ovary(8)|pancreas(1)|prostate(7)|skin(11)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(10)	248		Ovarian(17;0.0448)|Hepatocellular(203;0.218)		OV - Ovarian serous cystadenocarcinoma(123;4.92e-05)		GAACTTACCAAAGGACTGCCC	0.383													4	113	---	---	---	---
PCDHA6	56142	broad.mit.edu	37	5	140209758	140209758	+	Silent	SNP	G	G	T			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr5:140209758G>T	ENST00000529310.1	+	1	2196	c.2082G>T	c.(2080-2082)gtG>gtT	p.V694V	PCDHA3_ENST00000522353.2_Intron|PCDHA4_ENST00000512229.2_Intron|PCDHA2_ENST00000526136.1_Intron|PCDHA5_ENST00000529859.1_Intron|PCDHA1_ENST00000504120.2_Intron|PCDHA6_ENST00000527624.1_Intron|PCDHA1_ENST00000394633.3_Intron|PCDHA4_ENST00000530339.1_Intron|PCDHA5_ENST00000529619.1_Intron	NM_018909.2|NM_031848.2|NM_031849.1	NP_061732.1|NP_114036.1|NP_114037.1														NS(1)|breast(2)|cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(11)|lung(42)|prostate(8)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(1)	89			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			CGGCGCTGGTGGATGTCAACG	0.677													5	112	---	---	---	---
CDSN	1041	broad.mit.edu	37	6	31084574	31084574	+	Missense_Mutation	SNP	C	C	T			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr6:31084574C>T	ENST00000376288.2	-	2	844	c.818G>A	c.(817-819)tGt>tAt	p.C273Y	PSORS1C1_ENST00000259881.9_Intron|PSORS1C1_ENST00000467107.1_3'UTR	NM_001264.4	NP_001255	Q15517	CDSN_HUMAN	corneodesmosin	273	Ser-rich.				cell-cell adhesion|keratinocyte differentiation|skin morphogenesis	cornified envelope|desmosome|extracellular region	protein homodimerization activity			central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(3)|ovary(1)|pancreas(1)	10						ACCATTGCTACAGGGGGGACC	0.602													11	31	---	---	---	---
UTRN	7402	broad.mit.edu	37	6	144768388	144768388	+	Missense_Mutation	SNP	A	A	C			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr6:144768388A>C	ENST00000367545.3	+	14	1656	c.1656A>C	c.(1654-1656)ttA>ttC	p.L552F		NM_007124.2	NP_009055.2	P46939	UTRO_HUMAN	utrophin	552	Interaction with SYNM.				muscle contraction|muscle organ development|positive regulation of cell-matrix adhesion	cell junction|cytoplasm|cytoskeleton|membrane fraction|nucleus|postsynaptic membrane	actin binding|calcium ion binding|zinc ion binding			NS(1)|autonomic_ganglia(1)|breast(7)|central_nervous_system(1)|cervix(2)|endometrium(21)|kidney(10)|large_intestine(29)|lung(56)|ovary(5)|pancreas(1)|prostate(1)|skin(5)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	148		Ovarian(120;0.218)		OV - Ovarian serous cystadenocarcinoma(155;5.72e-07)|GBM - Glioblastoma multiforme(68;4.9e-05)|Colorectal(48;0.213)		AAGAGGCTTTAAATAAAGTCC	0.363													14	20	---	---	---	---
CSMD1	64478	broad.mit.edu	37	8	3611520	3611520	+	Missense_Mutation	SNP	T	T	A			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr8:3611520T>A	ENST00000520002.1	-	6	1418	c.863A>T	c.(862-864)aAt>aTt	p.N288I	CSMD1_ENST00000537824.1_Missense_Mutation_p.N288I|CSMD1_ENST00000602723.1_Missense_Mutation_p.N288I|CSMD1_ENST00000400186.3_Missense_Mutation_p.N288I|CSMD1_ENST00000542608.1_Missense_Mutation_p.N288I|CSMD1_ENST00000602557.1_Missense_Mutation_p.N288I|CSMD1_ENST00000539096.1_Missense_Mutation_p.N288I			Q96PZ7	CSMD1_HUMAN	CUB and Sushi multiple domains 1	288	CUB 2.					integral to membrane				breast(20)|large_intestine(5)	25		all_cancers(1;5.7e-41)|all_epithelial(1;2.54e-36)|Lung NSC(1;7.54e-11)|all_lung(1;3.2e-10)|Hepatocellular(1;3.78e-05)|Breast(1;0.000196)|Myeloproliferative disorder(4;0.000374)|Esophageal squamous(1;0.0157)|Ovarian(12;0.091)|Renal(68;0.144)|Colorectal(14;0.234)		all cancers(1;5.03e-41)|Epithelial(1;4.78e-31)|Lung(1;1.14e-14)|LUSC - Lung squamous cell carcinoma(1;2.34e-14)|GBM - Glioblastoma multiforme(1;4.49e-10)|Colorectal(4;1.18e-07)|OV - Ovarian serous cystadenocarcinoma(1;3.2e-07)|BRCA - Breast invasive adenocarcinoma(1;6.17e-07)|COAD - Colon adenocarcinoma(4;0.000539)|READ - Rectum adenocarcinoma(4;0.00896)|Kidney(5;0.00957)|KIRC - Kidney renal clear cell carcinoma(5;0.0689)		TCGTAGCCAATTCTTGCTACT	0.433													3	28	---	---	---	---
FAM111B	374393	broad.mit.edu	37	11	58893556	58893556	+	Silent	SNP	T	T	C			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr11:58893556T>C	ENST00000343597.3	+	4	2177	c.1986T>C	c.(1984-1986)gtT>gtC	p.V662V	FAM111B_ENST00000411426.1_Silent_p.V632V|FAM111B_ENST00000529618.1_Silent_p.V632V	NM_198947.3	NP_945185.1	Q6SJ93	F111B_HUMAN	family with sequence similarity 111, member B	662							catalytic activity			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(13)|liver(1)|lung(12)|ovary(3)|pancreas(1)|skin(1)	40						GCAAATTGGTTGCTTTGCATA	0.383													10	96	---	---	---	---
RSF1	51773	broad.mit.edu	37	11	77412452	77412452	+	Missense_Mutation	SNP	C	C	G			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr11:77412452C>G	ENST00000308488.6	-	6	2124	c.1822G>C	c.(1822-1824)Gaa>Caa	p.E608Q	RSF1_ENST00000480887.1_Missense_Mutation_p.E356Q|RSF1_ENST00000360355.2_Missense_Mutation_p.E577Q			Q96T23	RSF1_HUMAN	remodeling and spacing factor 1	608					CenH3-containing nucleosome assembly at centromere|negative regulation of DNA binding|negative regulation of transcription, DNA-dependent|nucleosome positioning|positive regulation of transcription, DNA-dependent|positive regulation of viral transcription|transcription initiation, DNA-dependent	RSF complex	histone binding|protein binding|zinc ion binding			breast(3)|central_nervous_system(2)|endometrium(3)|kidney(4)|large_intestine(9)|lung(14)|ovary(2)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	43	all_cancers(14;1.54e-17)|all_epithelial(13;4.06e-20)|Ovarian(111;0.152)		Epithelial(5;3e-50)|all cancers(3;6.37e-47)|BRCA - Breast invasive adenocarcinoma(5;9.82e-31)			GGAACTTCTTCTGGTATTGGA	0.423													33	64	---	---	---	---
HTR3B	9177	broad.mit.edu	37	11	113813797	113813797	+	Missense_Mutation	SNP	C	C	T			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr11:113813797C>T	ENST00000260191.2	+	7	1047	c.790C>T	c.(790-792)Cca>Tca	p.P264S	HTR3B_ENST00000537778.1_Missense_Mutation_p.P253S	NM_006028.4	NP_006019.1	O95264	5HT3B_HUMAN	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	264					synaptic transmission	integral to plasma membrane|postsynaptic membrane	serotonin receptor activity|serotonin-activated cation-selective channel activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(11)	20		all_cancers(61;6.81e-18)|all_epithelial(67;6.67e-11)|all_hematologic(158;4.67e-05)|Melanoma(852;0.000316)|Acute lymphoblastic leukemia(157;0.000976)|Breast(348;0.0101)|Prostate(24;0.0154)|all_neural(223;0.0281)|Medulloblastoma(222;0.0425)		BRCA - Breast invasive adenocarcinoma(274;3.04e-06)|Epithelial(105;1.98e-05)|all cancers(92;0.000201)|OV - Ovarian serous cystadenocarcinoma(223;0.151)		CTTCTACCTGCCACCCAACTG	0.587													16	23	---	---	---	---
FLRT2	23768	broad.mit.edu	37	14	86089586	86089586	+	Missense_Mutation	SNP	G	G	T			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr14:86089586G>T	ENST00000330753.4	+	2	2495	c.1728G>T	c.(1726-1728)aaG>aaT	p.K576N	FLRT2_ENST00000554746.1_Missense_Mutation_p.K576N	NM_013231.4	NP_037363.1	O43155	FLRT2_HUMAN	fibronectin leucine rich transmembrane protein 2	576					cell adhesion	integral to plasma membrane|proteinaceous extracellular matrix	protein binding, bridging|receptor signaling protein activity			NS(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(3)|kidney(7)|large_intestine(21)|lung(27)|ovary(3)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	73				BRCA - Breast invasive adenocarcinoma(234;0.0319)		CCTCCCAGAAGTGGAAATACA	0.542													4	100	---	---	---	---
PACS2	23241	broad.mit.edu	37	14	105818794	105818794	+	Missense_Mutation	SNP	T	T	C			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr14:105818794T>C	ENST00000447393.1	+	3	462	c.287T>C	c.(286-288)tTc>tCc	p.F96S	PACS2_ENST00000547217.1_Intron|PACS2_ENST00000325438.8_Missense_Mutation_p.F96S|PACS2_ENST00000458164.2_Missense_Mutation_p.F96S|PACS2_ENST00000430725.2_Missense_Mutation_p.F29S	NM_015197.3	NP_056012.2	Q86VP3	PACS2_HUMAN	phosphofurin acidic cluster sorting protein 2	96					apoptosis|interspecies interaction between organisms	endoplasmic reticulum lumen|mitochondrion				endometrium(2)|kidney(2)|lung(7)|ovary(3)|pancreas(1)|prostate(2)|skin(3)|urinary_tract(1)	21		all_cancers(154;0.0351)|all_epithelial(191;0.153)|Melanoma(154;0.155)	OV - Ovarian serous cystadenocarcinoma(23;0.0145)|Epithelial(46;0.036)	Epithelial(152;0.138)		GCCCTGACCTTCTCCTTGCAG	0.607											OREG0022968	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	17	47	---	---	---	---
CTDSPL2	51496	broad.mit.edu	37	15	44783110	44783110	+	Missense_Mutation	SNP	A	A	G			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr15:44783110A>G	ENST00000260327.4	+	5	1167	c.604A>G	c.(604-606)Aat>Gat	p.N202D	CTDSPL2_ENST00000558373.1_Intron|CTDSPL2_ENST00000396780.1_Intron|CTDSPL2_ENST00000558966.1_Missense_Mutation_p.N202D	NM_016396.2	NP_057480.2	Q05D32	CTSL2_HUMAN	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2	202							phosphoprotein phosphatase activity			breast(1)|endometrium(1)|kidney(2)|large_intestine(3)|lung(4)|upper_aerodigestive_tract(2)	13		all_cancers(109;4.36e-14)|all_epithelial(112;9.8e-12)|Lung NSC(122;1.66e-07)|all_lung(180;1.47e-06)|Melanoma(134;0.0122)		all cancers(107;1.02e-20)|GBM - Glioblastoma multiforme(94;1.49e-06)|COAD - Colon adenocarcinoma(120;0.0857)|Colorectal(105;0.0905)		AGCTTACTCAAATCAAGCAGT	0.393													27	57	---	---	---	---
ARL16	339231	broad.mit.edu	37	17	79650772	79650772	+	Silent	SNP	C	C	G			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr17:79650772C>G	ENST00000397498.4	-	1	182	c.84G>C	c.(82-84)ctG>ctC	p.L28L		NM_001040025.1	NP_001035114.1	Q0P5N6	ARL16_HUMAN	ADP-ribosylation factor-like 16	28							GTP binding			central_nervous_system(1)|endometrium(1)|lung(4)|skin(1)	7	all_neural(118;0.0878)|all_lung(278;0.23)		BRCA - Breast invasive adenocarcinoma(99;0.0101)|OV - Ovarian serous cystadenocarcinoma(97;0.0739)			TGGCCCCCAGCAGGAGACACA	0.701													4	9	---	---	---	---
KCNG2	26251	broad.mit.edu	37	18	77659468	77659468	+	Silent	SNP	C	C	T			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr18:77659468C>T	ENST00000316249.3	+	2	1053	c.1053C>T	c.(1051-1053)cgC>cgT	p.R351R	KCNG2_ENST00000590307.1_3'UTR	NM_012283.1	NP_036415.1	Q9UJ96	KCNG2_HUMAN	potassium voltage-gated channel, subfamily G, member 2	351					energy reserve metabolic process|regulation of heart contraction|regulation of insulin secretion	voltage-gated potassium channel complex	delayed rectifier potassium channel activity	p.R351R(1)		breast(2)|endometrium(4)|lung(7)|skin(1)|upper_aerodigestive_tract(4)	18		Esophageal squamous(42;0.0157)|Melanoma(33;0.144)		OV - Ovarian serous cystadenocarcinoma(15;6.92e-07)|BRCA - Breast invasive adenocarcinoma(31;0.0244)		GCGCGCGCCGCGACTTCTCCA	0.721													8	17	---	---	---	---
ERGIC3	51614	broad.mit.edu	37	20	34143849	34143849	+	Missense_Mutation	SNP	T	T	A			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr20:34143849T>A	ENST00000348547.2	+	9	840	c.763T>A	c.(763-765)Tat>Aat	p.Y255N	ERGIC3_ENST00000447986.1_Missense_Mutation_p.Y270N|ERGIC3_ENST00000279052.6_Missense_Mutation_p.Y260N|ERGIC3_ENST00000357394.4_Missense_Mutation_p.Y260N|ERGIC3_ENST00000482338.1_3'UTR	NM_015966.2	NP_057050.1	Q9Y282	ERGI3_HUMAN	ERGIC and golgi 3	255					vesicle-mediated transport	endoplasmic reticulum membrane|ER-Golgi intermediate compartment membrane|Golgi apparatus|integral to membrane	protein binding			breast(1)|central_nervous_system(1)|endometrium(4)|large_intestine(4)|lung(4)|ovary(1)|prostate(1)	16	Lung NSC(9;0.00489)|all_lung(11;0.00729)		BRCA - Breast invasive adenocarcinoma(18;0.0127)			TGGGGAGGACTATCCAGGCAT	0.587													43	98	---	---	---	---
EBNA1BP2	10969	broad.mit.edu	37	1	43630134	43630136	+	In_Frame_Del	DEL	TCT	TCT	-			TCGA-EJ-A7NF-01A-11D-A33T-08	TCGA-EJ-A7NF-10A-01D-A33W-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0a1f24ca-9ea6-45b4-aae1-2174a9670065	db974012-6d0c-44c3-ae87-e0f05d96abdc	g.chr1:43630134_43630136delTCT	ENST00000431635.2	-	10	1212_1214	c.1064_1066delAGA	c.(1063-1068)aagatg>atg	p.K355del	EBNA1BP2_ENST00000236051.2_In_Frame_Del_p.K300del	NM_001159936.1	NP_001153408.1	Q99848	EBP2_HUMAN	EBNA1 binding protein 2	300					ribosome biogenesis	membrane fraction|nucleolus	protein binding			endometrium(1)|kidney(2)|large_intestine(4)|lung(9)	16	Ovarian(52;0.00579)|all_hematologic(146;0.0977)|Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0505)				CTGTTCTTCATCTTCTCTCTTGT	0.424													32	50	---	---	---	---
