Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample
BNIPL	149428	broad.mit.edu	37	1	151011474	151011474	+	Silent	SNP	G	G	A			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr1:151011474G>A	ENST00000295294.7	+	4	768	c.159G>A	c.(157-159)ctG>ctA	p.L53L	BNIPL_ENST00000368931.3_Silent_p.L135L	NM_001159642.1	NP_001153114.1	Q7Z465	BNIPL_HUMAN	BCL2/adenovirus E1B 19kD interacting protein like	135					apoptosis|induction of apoptosis|negative regulation of cell proliferation|regulation of growth rate	cytosol|nucleus	identical protein binding			autonomic_ganglia(1)|endometrium(3)|large_intestine(1)|lung(4)|skin(1)	10	Lung SC(34;0.00471)|Ovarian(49;0.0167)|all_hematologic(923;0.0597)|Hepatocellular(266;0.0997)|Melanoma(130;0.185)		UCEC - Uterine corpus endometrioid carcinoma (35;0.0486)|LUSC - Lung squamous cell carcinoma(543;0.211)			CGGAGCAGCTGGACAGTGGAC	0.502													3	17	---	---	---	---
NR1I3	9970	broad.mit.edu	37	1	161203129	161203129	+	Splice_Site	SNP	C	C	A			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr1:161203129C>A	ENST00000367983.4	-	4	533		c.e4-1		NR1I3_ENST00000505005.1_Splice_Site|NR1I3_ENST00000511676.1_Splice_Site|NR1I3_ENST00000367979.2_Splice_Site|NR1I3_ENST00000508387.1_Intron|NR1I3_ENST00000508740.1_Splice_Site|NR1I3_ENST00000412844.2_Splice_Site|NR1I3_ENST00000515452.1_Splice_Site|NR1I3_ENST00000512372.1_Splice_Site|NR1I3_ENST00000504010.1_Splice_Site|NR1I3_ENST00000442691.2_Splice_Site|NR1I3_ENST00000502985.1_Intron|NR1I3_ENST00000367981.3_Splice_Site|NR1I3_ENST00000437437.2_Splice_Site|NR1I3_ENST00000511748.1_Intron|NR1I3_ENST00000367980.2_Splice_Site|NR1I3_ENST00000428574.2_Splice_Site|NR1I3_ENST00000367985.3_Splice_Site|NR1I3_ENST00000515621.1_Splice_Site|NR1I3_ENST00000367982.4_Splice_Site|NR1I3_ENST00000506209.1_Splice_Site|NR1I3_ENST00000367984.4_Splice_Site|NR1I3_ENST00000511944.1_Intron			Q14994	NR1I3_HUMAN	nuclear receptor subfamily 1, group I, member 3						regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	nucleoplasm	androgen receptor activity|protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|thyroid hormone receptor activity|transcription coactivator activity|zinc ion binding			endometrium(1)|kidney(1)|large_intestine(4)|lung(7)|ovary(1)|skin(1)	15	all_cancers(52;1.86e-18)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.00376)			GACAGTATCACTGTGCCAGGC	0.577													20	51	---	---	---	---
ARL13B	200894	broad.mit.edu	37	3	93769715	93769715	+	Missense_Mutation	SNP	C	C	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr3:93769715C>G	ENST00000535334.1	+	8	1403	c.880C>G	c.(880-882)Ctt>Gtt	p.L294V	ARL13B_ENST00000539730.1_Missense_Mutation_p.L118V|ARL13B_ENST00000394222.3_Missense_Mutation_p.L397V|ARL13B_ENST00000303097.7_Missense_Mutation_p.L290V|ARL13B_ENST00000471138.1_Missense_Mutation_p.L397V|DHFRL1_ENST00000481631.1_Intron	NM_001174151.1	NP_001167622.1	Q3SXY8	AR13B_HUMAN	ADP-ribosylation factor-like 13B	397							GTP binding			endometrium(1)|kidney(1)|large_intestine(3)|lung(3)|urinary_tract(2)	10						ACTTGAGCCTCTTGGTGAAAC	0.338													9	36	---	---	---	---
TRIM42	287015	broad.mit.edu	37	3	140397286	140397286	+	Missense_Mutation	SNP	A	A	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr3:140397286A>G	ENST00000286349.3	+	1	406	c.215A>G	c.(214-216)aAt>aGt	p.N72S		NM_152616.4	NP_689829.3	Q8IWZ5	TRI42_HUMAN	tripartite motif containing 42	72	Cys-rich.					intracellular	zinc ion binding			breast(1)|central_nervous_system(1)|cervix(2)|endometrium(2)|large_intestine(11)|lung(33)|ovary(2)|pancreas(1)|prostate(6)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(2)	69						TCTTGGGCCAATGATCCCAAC	0.537													17	53	---	---	---	---
ADAMTS19	171019	broad.mit.edu	37	5	128994429	128994429	+	Splice_Site	SNP	A	A	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr5:128994429A>G	ENST00000274487.4	+	15	2551	c.2406A>G	c.(2404-2406)gcA>gcG	p.A802A	CTC-575N7.1_ENST00000503616.1_RNA	NM_133638.3	NP_598377.3	Q8TE59	ATS19_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 19	802	Spacer.				proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			NS(1)|breast(4)|endometrium(10)|kidney(9)|large_intestine(14)|lung(34)|ovary(6)|pancreas(1)|prostate(6)|skin(6)	91		all_cancers(142;0.0148)|Prostate(80;0.0494)|Breast(839;0.238)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)	OV - Ovarian serous cystadenocarcinoma(64;0.222)		CCAGAGGAGCAGGTAATTTTT	0.313													13	38	---	---	---	---
PCDHA7	56141	broad.mit.edu	37	5	140215501	140215501	+	Silent	SNP	C	C	T			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr5:140215501C>T	ENST00000525929.1	+	1	1533	c.1533C>T	c.(1531-1533)caC>caT	p.H511H	PCDHA7_ENST00000378125.3_Silent_p.H511H|PCDHA6_ENST00000527624.1_Intron|PCDHA4_ENST00000530339.1_Intron|PCDHA3_ENST00000522353.2_Intron|PCDHA1_ENST00000394633.3_Intron|PCDHA5_ENST00000529619.1_Intron|PCDHA1_ENST00000504120.2_Intron|PCDHA4_ENST00000512229.2_Intron|PCDHA2_ENST00000526136.1_Intron|PCDHA5_ENST00000529859.1_Intron|PCDHA6_ENST00000529310.1_Intron	NM_018910.2	NP_061733.1														NS(2)|biliary_tract(1)|breast(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(27)|ovary(3)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	63			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			TGTCAGTGCACGCGGAGAGCG	0.706													36	97	---	---	---	---
PCDHA8	56140	broad.mit.edu	37	5	140222414	140222414	+	Nonsense_Mutation	SNP	C	C	A			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr5:140222414C>A	ENST00000531613.1	+	1	1508	c.1508C>A	c.(1507-1509)tCg>tAg	p.S503*	PCDHA6_ENST00000527624.1_Intron|PCDHA8_ENST00000378123.3_Nonsense_Mutation_p.S503*|PCDHA4_ENST00000530339.1_Intron|PCDHA3_ENST00000522353.2_Intron|PCDHA1_ENST00000394633.3_Intron|PCDHA5_ENST00000529619.1_Intron|PCDHA1_ENST00000504120.2_Intron|PCDHA7_ENST00000525929.1_Intron|PCDHA4_ENST00000512229.2_Intron|PCDHA2_ENST00000526136.1_Intron|PCDHA5_ENST00000529859.1_Intron|PCDHA6_ENST00000529310.1_Intron	NM_018911.2	NP_061734.1														NS(2)|breast(3)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(10)|lung(31)|ovary(2)|prostate(2)|skin(4)|stomach(2)|upper_aerodigestive_tract(6)	78			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GGCGAGCGCTCGCTGTCGAGC	0.667													18	61	---	---	---	---
PCDHB7	56129	broad.mit.edu	37	5	140554104	140554104	+	Missense_Mutation	SNP	A	A	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr5:140554104A>G	ENST00000231137.3	+	1	1862	c.1688A>G	c.(1687-1689)tAc>tGc	p.Y563C		NM_018940.2	NP_061763.1	Q9Y5E2	PCDB7_HUMAN		563					calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding	p.Y563F(1)		NS(2)|breast(2)|central_nervous_system(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(20)|lung(54)|ovary(5)|prostate(7)|skin(7)|upper_aerodigestive_tract(4)|urinary_tract(1)	119			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			TTCGTGCTGTACCCGCTGCAG	0.736													14	32	---	---	---	---
OR12D3	81797	broad.mit.edu	37	6	29342301	29342301	+	Missense_Mutation	SNP	C	C	A			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr6:29342301C>A	ENST00000396806.3	-	1	767	c.764G>T	c.(763-765)gGc>gTc	p.G255V	OR5V1_ENST00000377154.1_Intron	NM_030959.2	NP_112221.1	Q9UGF7	O12D3_HUMAN	olfactory receptor, family 12, subfamily D, member 3	255					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|endometrium(2)|kidney(2)|large_intestine(6)|lung(6)|ovary(2)|skin(1)|upper_aerodigestive_tract(3)	23						ATATGTGAAGCCCACAGGTCC	0.478													3	40	---	---	---	---
GLTSCR1L	23506	broad.mit.edu	37	6	42832986	42832986	+	Missense_Mutation	SNP	C	C	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr6:42832986C>G	ENST00000314073.5	+	13	3218	c.3042C>G	c.(3040-3042)atC>atG	p.I1014M	GLTSCR1L_ENST00000394168.1_Missense_Mutation_p.I1014M					GLTSCR1-like																		TTAAGAACATCTTGGAACTCA	0.493													11	31	---	---	---	---
BRAF	673	broad.mit.edu	37	7	140453134	140453134	+	Missense_Mutation	SNP	T	T	C	rs121913377		TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr7:140453134T>C	ENST00000288602.6	-	15	1861	c.1801A>G	c.(1801-1803)Aaa>Gaa	p.K601E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	601	Protein kinase.		K -> E (in colorectal cancer).|K -> Q (in CFC syndrome).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.K601E(40)|p.V600_K601>E(12)|p.T599_R603>I(2)|p.K601del(1)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	CATCGAGATTTCACTGTAGCT	0.368		61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				11	40	---	---	---	---
MUC2	4583	broad.mit.edu	37	11	1075772	1075772	+	Missense_Mutation	SNP	C	C	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr11:1075772C>G	ENST00000441003.2	+	2	225	c.198C>G	c.(196-198)gaC>gaG	p.D66E	MUC2_ENST00000359061.5_Missense_Mutation_p.D66E	NM_002457.2	NP_002448.2	Q02817	MUC2_HUMAN	mucin 2, oligomeric mucus/gel-forming	66	VWFD 1.					inner mucus layer|outer mucus layer	protein binding			NS(3)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(26)|haematopoietic_and_lymphoid_tissue(4)|kidney(11)|large_intestine(5)|lung(22)|ovary(2)|prostate(16)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)	102		all_cancers(49;1.08e-07)|all_epithelial(84;5.08e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.191)		BRCA - Breast invasive adenocarcinoma(625;0.000207)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)	Pranlukast(DB01411)	TCGCCTCCGACTGCCGAGGCT	0.642													7	9	---	---	---	---
MOGAT2	80168	broad.mit.edu	37	11	75442268	75442268	+	Missense_Mutation	SNP	C	C	A			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr11:75442268C>A	ENST00000526712.1	+	5	1469	c.696C>A	c.(694-696)aaC>aaA	p.N232K	MOGAT2_ENST00000198801.5_Missense_Mutation_p.N314K			Q3SYC2	MOGT2_HUMAN	monoacylglycerol O-acyltransferase 2	314					glycerol metabolic process	endoplasmic reticulum membrane|integral to membrane	2-acylglycerol O-acyltransferase activity			NS(1)|kidney(2)|large_intestine(2)|lung(11)|ovary(2)|skin(1)|urinary_tract(1)	20	Ovarian(111;0.103)					AGCTGTGCAACCTCTTCGAGG	0.567													16	44	---	---	---	---
HSPB2	3316	broad.mit.edu	37	11	111784196	111784196	+	Silent	SNP	A	A	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr11:111784196A>G	ENST00000304298.3	+	2	714	c.126A>G	c.(124-126)acA>acG	p.T42T	CRYAB_ENST00000527950.1_Intron|HSPB2-C11orf52_ENST00000534100.1_Intron|HSPB2_ENST00000537382.1_Silent_p.T42T|CRYAB_ENST00000533475.1_Intron	NM_001541.3	NP_001532.1	Q16082	HSPB2_HUMAN	heat shock 27kDa protein 2	42					response to heat|response to unfolded protein	cytosol|nucleus	enzyme activator activity|protein binding			large_intestine(2)|lung(3)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	10		all_cancers(61;3.75e-11)|all_epithelial(67;2.33e-06)|Melanoma(852;9.42e-06)|all_hematologic(158;0.000885)|Acute lymphoblastic leukemia(157;0.000966)|Breast(348;0.0512)|Medulloblastoma(222;0.0523)|all_neural(223;0.0663)		Epithelial(105;3.57e-07)|BRCA - Breast invasive adenocarcinoma(274;1.1e-06)|all cancers(92;6.57e-06)|OV - Ovarian serous cystadenocarcinoma(223;0.051)		TGACCCCCACACTCTACCATG	0.637													30	108	---	---	---	---
OR4K2	390431	broad.mit.edu	37	14	20344905	20344905	+	Missense_Mutation	SNP	T	T	G			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr14:20344905T>G	ENST00000298642.2	+	1	515	c.479T>G	c.(478-480)gTc>gGc	p.V160G		NM_001005501.1	NP_001005501.1	Q8NGD2	OR4K2_HUMAN	olfactory receptor, family 4, subfamily K, member 2	160					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|endometrium(5)|kidney(2)|large_intestine(6)|lung(16)|ovary(2)|skin(9)|upper_aerodigestive_tract(2)	43	all_cancers(95;0.00108)		Epithelial(56;9.96e-07)|all cancers(55;2.95e-06)	GBM - Glioblastoma multiforme(265;0.00327)		ATGAGTCAGGTCATATTTGCC	0.483													50	237	---	---	---	---
ITGAX	3687	broad.mit.edu	37	16	31382413	31382413	+	Silent	SNP	G	G	A			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr16:31382413G>A	ENST00000268296.4	+	15	1840	c.1719G>A	c.(1717-1719)gcG>gcA	p.A573A	ITGAX_ENST00000562522.1_Silent_p.A573A	NM_000887.3	NP_000878.2	P20702	ITAX_HUMAN	integrin, alpha X (complement component 3 receptor 4 subunit)	573					blood coagulation|cell adhesion|integrin-mediated signaling pathway|leukocyte migration|organ morphogenesis	integrin complex	protein binding|receptor activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(8)|lung(42)|ovary(2)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	77						AGCGGATCGCGGGCTCCCAGC	0.582													14	50	---	---	---	---
ZNF536	9745	broad.mit.edu	37	19	31038939	31038939	+	Missense_Mutation	SNP	C	C	T			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr19:31038939C>T	ENST00000355537.3	+	4	2560	c.2413C>T	c.(2413-2415)Cgg>Tgg	p.R805W		NM_014717.1	NP_055532.1	O15090	ZN536_HUMAN	zinc finger protein 536	805					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	zinc ion binding			NS(3)|breast(6)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(22)|lung(119)|ovary(7)|prostate(4)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(3)	182	Esophageal squamous(110;0.0834)					CCATCGGGAGCGGCAGAACGG	0.537													8	33	---	---	---	---
SERHL	94009	broad.mit.edu	37	22	42905063	42905063	+	RNA	SNP	G	G	A			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr22:42905063G>A	ENST00000359906.2	+	0	644					NR_027786.1				serine hydrolase-like											endometrium(1)|large_intestine(1)	2						TCGTCAGCAGGGAGCTGTGTG	0.552													9	36	---	---	---	---
EHHADH	1962	broad.mit.edu	37	3	184922509	184922509	+	Frame_Shift_Del	DEL	G	G	-			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr3:184922509delG	ENST00000231887.3	-	6	680	c.605delC	c.(604-606)ccafs	p.P202fs	EHHADH_ENST00000456310.1_Frame_Shift_Del_p.P106fs	NM_001166415.1|NM_001966.3	NP_001159887.1|NP_001957.2	Q08426	ECHP_HUMAN	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	202	Enoyl-CoA hydratase / isomerase.					peroxisome	3-hydroxyacyl-CoA dehydrogenase activity|coenzyme binding|dodecenoyl-CoA delta-isomerase activity|enoyl-CoA hydratase activity			breast(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(9)|ovary(3)|prostate(2)|skin(3)	24	all_cancers(143;4.04e-11)|Ovarian(172;0.0339)|Breast(254;0.247)		Epithelial(37;1.98e-32)|OV - Ovarian serous cystadenocarcinoma(80;5.55e-21)		NADH(DB00157)	GCTCTGAATTGGCTTGTTGCA	0.468													13	79	---	---	---	---
IKBIP	121457	broad.mit.edu	37	12	99007629	99007635	+	Frame_Shift_Del	DEL	AGCTTAG	AGCTTAG	-			TCGA-V1-A8MU-01A-11D-A377-08	TCGA-V1-A8MU-10A-01D-A37A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	942a31bd-5417-43df-bc54-b74f9d8745ce	3f2fdbd9-19b0-41e2-87f3-ebc0f5fa5215	g.chr12:99007629_99007635delAGCTTAG	ENST00000342502.2	-	3	1192_1198	c.781_787delCTAAGCT	c.(781-789)ctaagcttafs	p.LSL261fs	IKBIP_ENST00000420861.1_Frame_Shift_Del_p.LSL155fs|IKBIP_ENST00000393042.3_3'UTR	NM_201612.2	NP_963906.1	Q70UQ0	IKIP_HUMAN	IKBKB interacting protein	261					induction of apoptosis|response to X-ray	endoplasmic reticulum membrane|integral to membrane	protein binding			NS(1)|kidney(1)|large_intestine(1)|lung(1)|prostate(2)	6						TCACCTTCTAAGCTTAGAAATCTATCT	0.377													17	47	---	---	---	---
