Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
HIST1H1E	3008	broad.mit.edu	37	6	26156924	26156924	+	Silent	SNP	G	T	T			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr6:26156924G>T	uc003ngq.3	+	0	366	c.306G>T	c.(304-306)tcG>tcT	p.S102S	HIST1H2BD_uc003ngr.3_5'Flank|HIST1H2BD_uc003ngs.3_5'Flank	NM_005321	NP_005312	P10412	H14_HUMAN	Homo sapiens histone cluster 1, H1e (HIST1H1E), mRNA.	102	H15.				nucleosome assembly	nucleosome|nucleus	DNA binding|protein binding			NS(2)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(1)|liver(1)|lung(9)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)	26						CCGGCGCGTCGGGTTCCTTCA	0.612000														70			3		0.150653	0.160069	1	1	0
CYP2D7P1	1564	broad.mit.edu	37	22	42538870	42538870	+	Missense_Mutation	SNP	A	C	C	rs2982057	by1000genomes	TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr22:42538870A>C	uc003bci.3	-	2	475	c.94T>G	c.(94-96)Tcg>Gcg	p.S32A	CYP2D7P1_uc003bcg.3_5'Flank|CYP2D7P1_uc010gyv.3_Intron|CYP2D7P1_uc010gyw.3_Non-coding_Transcript|CYP2D7P1_uc021wqk.1_5'Flank|CYP2D7P1_uc010gyx.1_Missense_Mutation_p.S32A					Homo sapiens cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 1 (CYP2D7P1), non-coding RNA.											endometrium(1)	1						CCATAGCGCGACAGGAACACC	0.687000														52			3		0	0	1	0	0
FLJ36000	284124	broad.mit.edu	37	17	21904204	21904204	+	RNA	SNP	G	T	T			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr17:21904204G>T	uc002gza.2	+	0		c.143G>T								Homo sapiens uncharacterized FLJ36000 (FLJ36000), non-coding RNA.																		ctgccaggacggtgttcgggt	0.677000														174			11		0.010729	0.0121596	1	1	0
ZNF845	91664	broad.mit.edu	37	19	53855365	53855365	+	Silent	SNP	A	G	G			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr19:53855365A>G	uc010ydv.1	+	3	1554	c.1437A>G	c.(1435-1437)acA>acG	p.T479T	ZNF845_uc010ydw.1_Silent_p.T479T	NM_138374	NP_612383	Q96IR2	ZN845_HUMAN	Homo sapiens zinc finger protein 845 (ZNF845), mRNA.	479					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(2)|kidney(10)|lung(7)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|urinary_tract(2)	26						TCAGTCAGACATCATCCCTTG	0.378000														123			4		0	0	1	0	0
TOR1AIP2	163590	broad.mit.edu	37	1	179815714	179815714	+	Missense_Mutation	SNP	C	A	A			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr1:179815714C>A	uc001gnl.3	-	6	1719	c.905G>T	c.(904-906)cGg>cTg	p.R302L	TOR1AIP2_uc001gnk.3_Missense_Mutation_p.R302L	NM_001199260	NP_001186189	Q8NFQ8	TOIP2_HUMAN	Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 3, mRNA.	302						endoplasmic reticulum membrane|integral to membrane	protein binding	p.R302L(2)		cervix(1)|endometrium(3)|large_intestine(1)|lung(10)|ovary(1)|skin(2)	18						TCTTCCCTCCCGAGCTGCTGT	0.542000														141			4		1	1	1	1	0
MUC4	4585	broad.mit.edu	37	3	195511945	195511945	+	Missense_Mutation	SNP	G	A	A			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr3:195511945G>A	uc021xjp.1	-	1	6662	c.6506C>T	c.(6505-6507)gCa>gTa	p.A2169V	MUC4_uc003fvo.3_Intron|MUC4_uc003fvp.3_Intron	NM_018406	NP_060876	Q99102	MUC4_HUMAN	Homo sapiens mucin 4, cell surface associated (MUC4), transcript variant 1, mRNA.	948					cell-matrix adhesion	integral to plasma membrane|proteinaceous extracellular matrix	ErbB-2 class receptor binding|extracellular matrix constituent, lubricant activity	p.A2169V(4)		NS(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(5)|lung(23)|ovary(3)|prostate(8)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	51	all_cancers(143;1.11e-08)|Ovarian(172;0.0634)|Breast(254;0.206)	Lung NSC(153;0.191)	Epithelial(36;3.72e-24)|all cancers(36;6.22e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.1e-18)|Lung(62;4.65e-05)|LUSC - Lung squamous cell carcinoma(58;5.31e-05)	GBM - Glioblastoma multiforme(46;2.37e-05)		ACCTGTGGATGCTGAGGAAGT	0.572000														12			3		0	0	1	0	0
PRB1	5542	broad.mit.edu	37	12	11506566	11506566	+	Silent	SNP	C	T	T			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr12:11506566C>T	uc001qzw.1	-	3	505	c.468G>A	c.(466-468)aaG>aaA	p.K156K	PRB1_uc001qzu.1_Intron|PRB1_uc001qzv.1_Intron	NM_005039	NP_005030	P04280	PRP1_HUMAN	Homo sapiens proline-rich protein BstNI subfamily 1 (PRB1), transcript variant 1, mRNA.	157	15 X 20 AA approximate tandem repeats of P-P-G-K-P-Q-G-P-P-[PAQ]-Q-[GE]-[GD]- [NKS]-[KSQRN]-[PRQS]-[QS] [GPS]-[PQAR]- [PSR].		Missing (in allele S).|Missing (in clone CP-4).|Missing (in clone CP-5).			extracellular region				NS(1)|central_nervous_system(1)|kidney(4)|large_intestine(1)|lung(9)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	20			OV - Ovarian serous cystadenocarcinoma(49;0.185)			GTCCTTGTGGCTTTCCTGGAG	0.597000														69			6		0	0	1	0	0
GGT3P	2679	broad.mit.edu	37	22	18778601	18778601	+	RNA	SNP	C	T	T			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr22:18778601C>T	uc011ago.1	-	1		c.219G>A			GGT3P_uc011agp.1_Non-coding_Transcript|GGT3P_uc002zob.1_Non-coding_Transcript					Homo sapiens gamma-glutamyltransferase 3 pseudogene (GGT3P), non-coding RNA.																		GCTTGGCATCCGCGGCCACGG	0.627000														12			6		0	0	1	0	0
ZNF708	7562	broad.mit.edu	37	19	21476519	21476519	+	Missense_Mutation	SNP	T	C	C			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr19:21476519T>C	uc002npq.1	-	3	1447	c.1249A>G	c.(1249-1251)Aag>Gag	p.K417E	ZNF708_uc002npr.1_Missense_Mutation_p.K353E|ZNF708_uc010ecs.1_Missense_Mutation_p.K353E	NM_021269	NP_067092	P17019	ZN708_HUMAN	Homo sapiens zinc finger protein 708 (ZNF708), mRNA.	417					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|central_nervous_system(6)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(9)|ovary(2)|skin(2)|stomach(1)	32						TAGGGTTTCTTTCCAGTATGA	0.343000														57			3		0	0	1	0	0
TAOK2	9344	broad.mit.edu	37	16	29998500	29998500	+	Silent	SNP	G	C	C			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr16:29998500G>C	uc010bzm.2	+	14	2963	c.2928G>C	c.(2926-2928)ctG>ctC	p.L976L	BOLA2_uc010bzb.1_Intron|TAOK2_uc002dvb.2_Intron|TAOK2_uc021tgf.1_Silent_p.L856L|TAOK2_uc002dva.2_Silent_p.L969L|TAOK2_uc002dvc.2_Intron|TAOK2_uc002dvd.2_Silent_p.L796L	NM_016151	NP_057235	Q9UL54	TAOK2_HUMAN	Homo sapiens TAO kinase 2 (TAOK2), transcript variant 1, mRNA.	969	Leu-rich.				actin cytoskeleton organization|activation of MAPKK activity|apoptosis|cell migration|focal adhesion assembly|positive regulation of JNK cascade|protein targeting to membrane|regulation of cell growth|regulation of cell shape|response to stress	cytoplasmic vesicle membrane|cytoskeleton|dendrite|integral to membrane|nucleolus	ATP binding|protein serine/threonine kinase activity			breast(1)|endometrium(3)|large_intestine(5)|lung(8)|ovary(1)|prostate(3)|skin(1)	22						TGCCCCTCCTGCTGCTGCTGC	0.711000														88			3		0	0	1	0	0
BAGE1	0	broad.mit.edu	37	GL000237.1	2603	2603	+	RNA	SNP	C	G	G			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chrGL000237.1:2603C>G	uc011mgu.1	-	0		c.84G>C								Homo sapiens B melanoma antigen variant f (BAGE1) mRNA, complete cds, alternatively spliced.																		gttacaggctccagcctccag	0.612000														9			3		0	0	1	0	0
TUBA1B	10376	broad.mit.edu	37	12	49522057	49522057	+	Missense_Mutation	SNP	C	A	A			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr12:49522057C>A	uc001rtm.3	-	3	1261	c.1040G>T	c.(1039-1041)tGc>tTc	p.C347F	TUBA1B_uc021qxn.1_Missense_Mutation_p.C145F|TUBA1B_uc001rtl.3_Missense_Mutation_p.C312F|TUBA1A_uc010smg.1_5'UTR	NM_006082	NP_006073	P68363	TBA1B_HUMAN	Homo sapiens tubulin, alpha 1b (TUBA1B), mRNA.	347					'de novo' posttranslational protein folding|microtubule-based movement|protein polymerization	cytoplasm|microtubule	GTP binding|GTPase activity|protein binding			breast(2)|cervix(1)|endometrium(3)|large_intestine(2)|lung(4)	12						GCCAGTGGGGCACCAATCCAC	0.557000														56			6		0.00307968	0.00373961	1	1	0
MYH10	4628	broad.mit.edu	37	17	8397110	8397110	+	Missense_Mutation	SNP	C	G	G			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr17:8397110C>G	uc002glm.3	-	31	4246	c.4150G>C	c.(4150-4152)Gag>Cag	p.E1384Q	MYH10_uc002gll.3_Missense_Mutation_p.E1353Q|MYH10_uc010cnx.3_Missense_Mutation_p.E1362Q	NM_005964	NP_005955	P35580	MYH10_HUMAN	Homo sapiens myosin, heavy chain 10, non-muscle (MYH10), transcript variant 2, mRNA.	1353					actin filament-based movement|axon guidance|cytokinesis after mitosis|regulation of cell shape	cell cortex|cleavage furrow|midbody|myosin complex|stress fiber	ADP binding|ATP binding|actin filament binding|actin-dependent ATPase activity|calmodulin binding|microfilament motor activity			breast(5)|endometrium(9)|kidney(2)|large_intestine(16)|lung(9)|ovary(3)|prostate(3)|skin(4)|stomach(1)	52						TCCTCCTCCTCCTGCTGCTCC	0.587000														71			3		0	0	1	0	0
CLASP2	23122	broad.mit.edu	37	3	33602361	33602361	+	Frame_Shift_Del	DEL	T	-	-			TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr3:33602361delT	uc021wvc.1	-	27	3104	c.2893delA	c.(2893-2895)atgfs	p.M965fs	CLASP2_uc003cfs.3_Frame_Shift_Del_p.M164fs|CLASP2_uc021wva.1_Frame_Shift_Del_p.M39fs|CLASP2_uc021wvb.1_Frame_Shift_Del_p.M744fs|CLASP2_uc011axt.1_Frame_Shift_Del_p.M557fs	NM_015097	NP_055912	B2RTR1	B2RTR1_HUMAN	Homo sapiens cytoplasmic linker associated protein 2 (CLASP2), transcript variant 1, mRNA.	966										breast(2)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(19)|ovary(3)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	48						TCAGCACCCATTTTTTTTAGT	0.343													---	164	---	---	8	---					
HTT	3064	broad.mit.edu	37	4	3076604	3076609	+	In_Frame_Del	DEL	CAGCAG	-	-	rs71180116		TCGA-DA-A3F2-06A-11D-A20D-08	TCGA-DA-A3F2-10A-01D-A20D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	635a1c2f-50dd-4f35-b90c-d83ca860fba1	330fdd5b-7536-4de7-be64-511963e75655	g.chr4:3076604_3076609delCAGCAG	uc021xkv.1	+	0	197_202	c.52_57delCAGCAG	c.(52-57)cagcagdel	p.QQ36del	HTT-AS1_uc021xku.1_5'Flank	NM_002111	NP_002102	P42858	HD_HUMAN	Homo sapiens huntingtin (HTT), mRNA.	36	Poly-Gln.				Golgi organization|establishment of mitotic spindle orientation|retrograde vesicle-mediated transport, Golgi to ER|vesicle transport along microtubule	Golgi apparatus|autophagic vacuole|axon|cytoplasmic vesicle membrane|cytosol|dendrite|endoplasmic reticulum|late endosome|membrane fraction|nucleus|protein complex	beta-tubulin binding|dynactin binding|dynein intermediate chain binding|p53 binding|transcription factor binding			breast(1)|cervix(2)|endometrium(14)|kidney(5)|large_intestine(23)|lung(28)|ovary(4)|prostate(2)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	87		all_epithelial(65;0.18)		UCEC - Uterine corpus endometrioid carcinoma (64;0.187)		CAAGTCCTTCcagcagcagcagcagc	0.704													---	4	---	---	3	---					
