Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
TUBB8	347688	broad.mit.edu	37	10	93548	93548	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr10:93548G>A	uc001ifi.2	-	3	784	c.784C>T	c.(784-786)Cgg>Tgg	p.R262W		NM_177987	NP_817124	Q3ZCM7	TBB8_HUMAN	Homo sapiens tubulin, beta 8 class VIII (TUBB8), transcript variant 1, mRNA.	262					microtubule-based movement|protein polymerization	cytoplasm|microtubule	GTP binding|GTPase activity|structural molecule activity			NS(1)|cervix(1)|endometrium(4)|large_intestine(5)|lung(12)|ovary(2)|prostate(3)|skin(3)|stomach(1)	32		all_cancers(4;0.00131)|all_lung(4;0.000777)|Lung NSC(4;0.0043)|all_epithelial(10;0.0154)|Colorectal(49;0.235)		Epithelial(11;0.00341)|all cancers(11;0.00922)|OV - Ovarian serous cystadenocarcinoma(14;0.0508)|Lung(33;0.132)		AAATGCAGCCGGGGAAACGGG	0.627000														31			6		0	0	0.001168	0	0
NKTR	4820	broad.mit.edu	37	3	42679557	42679557	+	Missense_Mutation	SNP	A	C	C			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr3:42679557A>C	uc003clo.3	+	12	2508	c.2361A>C	c.(2359-2361)aaA>aaC	p.K787N	NKTR_uc003clm.1_Missense_Mutation_p.K534N|NKTR_uc011azp.2_Intron|NKTR_uc003clp.3_Missense_Mutation_p.K534N|NKTR_uc003clq.1_Missense_Mutation_p.K677N|NKTR_uc003clr.1_Missense_Mutation_p.K534N|NKTR_uc003cls.3_Missense_Mutation_p.K487N	NM_005385	NP_005376	P30414	NKTR_HUMAN	Homo sapiens natural killer-tumor recognition sequence (NKTR), mRNA.	787	Arg/Ser-rich.				protein folding	membrane	cyclosporin A binding|peptidyl-prolyl cis-trans isomerase activity			breast(3)|central_nervous_system(1)|endometrium(7)|kidney(2)|large_intestine(6)|lung(10)|ovary(3)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(4)	41				KIRC - Kidney renal clear cell carcinoma(284;0.24)		AATATGTCAAAGGTAGAGACA	0.408000														49			41		0	0	0.008740	0	0
DDX12P	440081	broad.mit.edu	37	12	9580293	9580293	+	RNA	SNP	A	G	G	rs139954536	by1000genomes	TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr12:9580293A>G	uc021qut.1	-	4		c.329T>C			DDX12P_uc001qvx.4_Non-coding_Transcript					Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene (DDX12P), non-coding RNA.									p.M473T(1)									CTTCAGCTCCATCCCTGAGAA	0.502000														87			6		0	0	0.001168	0	0
ATAD5	79915	broad.mit.edu	37	17	29220572	29220572	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr17:29220572G>A	uc002hfs.1	+	20	5044	c.4701G>A	c.(4699-4701)aaG>aaA	p.K1567K		NM_024857	NP_079133	Q96QE3	ATAD5_HUMAN	Homo sapiens ATPase family, AAA domain containing 5 (ATAD5), mRNA.	1567					response to DNA damage stimulus	nucleus	ATP binding|nucleoside-triphosphatase activity			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(8)|kidney(3)|large_intestine(18)|lung(13)|ovary(3)|pancreas(1)	51		all_hematologic(16;0.0202)|Acute lymphoblastic leukemia(14;0.0238)|Myeloproliferative disorder(56;0.0393)				AGAAACAAAAGAAAACATTGG	0.373000														29			14		0	0	0.002450	0	0
MYO15A	51168	broad.mit.edu	37	17	18022636	18022636	+	Silent	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr17:18022636C>T	uc021trm.1	+	0	741	c.522C>T	c.(520-522)ttC>ttT	p.F174F	MYO15A_uc021trl.1_Silent_p.F174F	NM_016239	NP_057323	Q9UKN7	MYO15_HUMAN	Homo sapiens myosin XVA (MYO15A), mRNA.	174	Myosin head-like.				sensory perception of sound	cytoplasm|myosin complex|stereocilium	ATP binding|actin binding|calmodulin binding|motor activity			breast(5)|central_nervous_system(2)|endometrium(17)|kidney(3)|large_intestine(16)|lung(27)|ovary(3)|pancreas(1)|prostate(6)|skin(13)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	99	all_neural(463;0.228)					AACTCCCCTTCCCGTCGGGTG	0.711000														27			24		0	0	0.004656	0	0
STOML3	161003	broad.mit.edu	37	13	39550878	39550878	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr13:39550878G>A	uc001uwx.3	-	1	247	c.109C>T	c.(109-111)Ctg>Ttg	p.L37L	STOML3_uc010tez.2_Silent_p.L28L	NM_145286	NP_660329	Q8TAV4	STML3_HUMAN	Homo sapiens stomatin (EPB72)-like 3 (STOML3), transcript variant 1, mRNA.	37						integral to membrane|plasma membrane				breast(1)|large_intestine(2)|lung(5)|ovary(1)|prostate(1)|skin(1)	11		Lung NSC(96;1.42e-05)|Prostate(109;0.00851)|Breast(139;0.0199)|Lung SC(185;0.0743)		all cancers(112;2.93e-08)|Epithelial(112;3.64e-06)|OV - Ovarian serous cystadenocarcinoma(117;0.00107)|BRCA - Breast invasive adenocarcinoma(63;0.00349)|GBM - Glioblastoma multiforme(144;0.0137)		ATCACCAACAGGAAAGAGAGG	0.418000														17			11		0	0	0.013537	0	0
PPP1R3A	5506	broad.mit.edu	37	7	113519545	113519545	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr7:113519545G>A	uc010ljy.1	-	3	1633	c.1602C>T	c.(1600-1602)ttC>ttT	p.F534F		NM_002711	NP_002702	Q16821	PPR3A_HUMAN	Homo sapiens protein phosphatase 1, regulatory subunit 3A (PPP1R3A), mRNA.	534					glycogen metabolic process	integral to membrane				NS(2)|breast(8)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(14)|liver(1)|lung(43)|ovary(10)|pancreas(7)|prostate(3)|skin(15)|stomach(1)|upper_aerodigestive_tract(2)	121						AGATTGTTTGGAAATTTTTTC	0.373000														24			21		0	0	0.008871	0	0
DMRT2	10655	broad.mit.edu	37	9	1056913	1056913	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr9:1056913G>A	uc003zha.3	+	3	1526	c.1326G>A	c.(1324-1326)acG>acA	p.T442T	DMRT2_uc003zhb.4_3'UTR|DMRT2_uc003zgy.4_Silent_p.T286T|DMRT2_uc011llt.2_3'UTR|DMRT2_uc022bcw.1_3'UTR|DMRT2_uc011llv.2_Silent_p.T442T	NM_181872	NP_870987	Q9Y5R5	DMRT2_HUMAN	Homo sapiens doublesex and mab-3 related transcription factor 2 (DMRT2), transcript variant 3, mRNA.	442					male gonad development|sex determination	nucleus	DNA binding|metal ion binding|sequence-specific DNA binding transcription factor activity	p.T442T(1)		large_intestine(1)|lung(1)|prostate(2)	4		all_lung(10;1.49e-09)|Lung NSC(10;1.86e-09)		Lung(218;0.0195)|GBM - Glioblastoma multiforme(50;0.0388)		TTGTTGACACGGACTCCCTGG	0.527000														15			80		0	0	0.014410	0	0
OTUD7A	161725	broad.mit.edu	37	15	31862357	31862357	+	Silent	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr15:31862357C>T	uc001zfq.3	-	1	288	c.195G>A	c.(193-195)caG>caA	p.Q65Q	OTUD7A_uc001zfr.3_Silent_p.Q65Q|OTUD7A_uc001zfs.1_Non-coding_Transcript|OTUD7A_uc010baa.1_Silent_p.Q65Q	NM_130901	NP_570971	Q8TE49	OTU7A_HUMAN	Homo sapiens OTU domain containing 7A (OTUD7A), mRNA.	65						cytoplasm|nucleus	DNA binding|cysteine-type peptidase activity|zinc ion binding			endometrium(7)|large_intestine(4)|lung(11)|pancreas(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(4)	30		all_lung(180;1.6e-09)		all cancers(64;2.44e-19)|Epithelial(43;6.82e-14)|GBM - Glioblastoma multiforme(186;1.49e-05)|BRCA - Breast invasive adenocarcinoma(123;0.00189)|Lung(196;0.208)		CCTGGCGGAGCTGCTCATAGT	0.567000														43			37		0	0	0.007835	0	0
SALL4	57167	broad.mit.edu	37	20	50400980	50400980	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr20:50400980G>A	uc002xwh.4	-	3	3087	c.2986C>T	c.(2986-2988)Cct>Tct	p.P996S	SALL4_uc010gii.3_Missense_Mutation_p.P559S|SALL4_uc002xwi.4_Missense_Mutation_p.P219S	NM_020436	NP_065169	Q9UJQ4	SALL4_HUMAN	Homo sapiens sal-like 4 (Drosophila) (SALL4), mRNA.	996					transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(7)|lung(27)|ovary(5)|prostate(2)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(1)	63						GGGAGGGTAGGAACCCCCCCA	0.557000														71			28		0	0	0.007291	0	0
NID2	22795	broad.mit.edu	37	14	52507401	52507401	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr14:52507401G>A	uc001wzo.3	-	7	2228	c.1994C>T	c.(1993-1995)cCc>cTc	p.P665L	NID2_uc010tqs.2_Missense_Mutation_p.P665L|NID2_uc010tqt.1_Missense_Mutation_p.P665L|NID2_uc001wzp.3_Missense_Mutation_p.P665L	NM_007361	NP_031387	Q14112	NID2_HUMAN	Homo sapiens nidogen 2 (osteonidogen) (NID2), mRNA.	665	Nidogen G2 beta-barrel.					basement membrane	calcium ion binding|collagen binding			NS(1)|breast(5)|endometrium(9)|kidney(4)|large_intestine(11)|liver(1)|lung(40)|ovary(2)|pancreas(2)|prostate(2)|skin(3)|soft_tissue(1)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	87	Breast(41;0.0639)|all_epithelial(31;0.123)					CTCCTTGTAGGGAGAGATGTG	0.473000														88			64		0	0	0.014410	0	0
TAS2R60	338398	broad.mit.edu	37	7	143141130	143141130	+	Silent	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr7:143141130C>T	uc011ktg.2	+	0	585	c.585C>T	c.(583-585)ttC>ttT	p.F195F	LOC285965_uc003wda.3_Intron	NM_177437	NP_803186	P59551	T2R60_HUMAN	Homo sapiens taste receptor, type 2, member 60 (TAS2R60), mRNA.	195					sensory perception of bitter taste	integral to membrane	G-protein coupled receptor activity	p.L194F(1)		breast(1)|kidney(1)|large_intestine(2)|lung(17)|prostate(1)|skin(7)|urinary_tract(2)	31	Melanoma(164;0.172)					TCTATCTCTTCCCTCTAAAAA	0.423000														97			67		0	0	0.014410	0	0
CDH6	1004	broad.mit.edu	37	5	31317540	31317540	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr5:31317540C>T	uc003jhe.2	+	9	1931	c.1571C>T	c.(1570-1572)tCg>tTg	p.S524L	CDH6_uc003jhd.2_Missense_Mutation_p.S524L	NM_004932	NP_004923	P55285	CADH6_HUMAN	Homo sapiens cadherin 6, type 2, K-cadherin (fetal kidney) (CDH6), mRNA.	524	Cadherin 5.				adherens junction organization|cell junction assembly|homophilic cell adhesion	cytoplasm|integral to membrane|nucleus|plasma membrane	calcium ion binding			NS(3)|central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(9)|lung(42)|ovary(4)|prostate(6)|skin(7)|upper_aerodigestive_tract(2)|urinary_tract(1)	77						CACCAATTTTCGTTTTCCTTG	0.403000														14			43		0	0	0.013114	0	0
RGPD4	285190	broad.mit.edu	37	2	108477279	108477279	+	Missense_Mutation	SNP	T	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr2:108477279T>A	uc010ywk.2	+	12	1898	c.1816T>A	c.(1816-1818)Tat>Aat	p.Y606N	RGPD4_uc002tdu.3_5'UTR|RGPD4_uc010ywl.2_Non-coding_Transcript	NM_182588	NP_872394	Q7Z3J3	RGPD4_HUMAN	Homo sapiens RANBP2-like and GRIP domain containing 4 (RGPD4), mRNA.	606					intracellular transport		binding			breast(1)|endometrium(7)|kidney(4)|lung(23)|pancreas(1)|prostate(1)|skin(3)|urinary_tract(3)	43						AAGTGTTCATTATTGGAAGAA	0.323000														81			58		0	0	0.014410	0	0
NBPF10	100132406	broad.mit.edu	37	1	145293274	145293274	+	Splice_Site	SNP	T	G	G	rs4525095	by1000genomes	TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr1:145293274T>G	uc021ouk.1	+	5	1163	c.-35_splice	c.e5+2		NBPF10_uc021ots.1_Intron|NBPF10_uc010oye.2_Intron|NBPF10_uc010oyh.1_Intron|NBPF10_uc021oul.1_5'Flank|NBPF10_uc001emq.1_5'UTR	NM_001037675	NP_001032764	A6NDV3	A6NDV3_HUMAN	Homo sapiens neuroblastoma breakpoint family, member 9 (NBPF9), mRNA.											NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		CAACAGTAAGTTAAGAATTTC	0.428000														108			107		0	0	0.014410	0	0
PELI2	57161	broad.mit.edu	37	14	56746398	56746398	+	Missense_Mutation	SNP	T	G	G			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr14:56746398T>G	uc001xch.3	+	2	498	c.212T>G	c.(211-213)aTc>aGc	p.I71S		NM_021255	NP_067078	Q9HAT8	PELI2_HUMAN	Homo sapiens pellino homolog 2 (Drosophila) (PELI2), mRNA.	71					MyD88-dependent toll-like receptor signaling pathway|Toll signaling pathway|innate immune response|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of MAPKKK cascade|positive regulation of protein phosphorylation|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway	cytosol	protein binding			kidney(6)|large_intestine(3)|lung(11)|ovary(1)|skin(1)	22						tattaGGCTATCAGCTGCAAA	0.378000														35			33		0	0	0.013726	0	0
TSHZ2	128553	broad.mit.edu	37	20	51871926	51871926	+	Silent	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr20:51871926C>T	uc002xwo.3	+	1	2816	c.1929C>T	c.(1927-1929)gcC>gcT	p.A643A	TSHZ2_uc021wex.1_Silent_p.A640A	NM_173485	NP_775756	Q9NRE2	TSH2_HUMAN	Homo sapiens teashirt zinc finger homeobox 2 (TSHZ2), transcript variant 1, mRNA.	643					multicellular organismal development	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(2)|breast(4)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(16)|lung(38)|ovary(5)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	84			STAD - Stomach adenocarcinoma(23;0.1)			CTCCAGAAGCCAAAAAGACCG	0.557000														44			64		0	0	0.014410	0	0
SGCZ	137868	broad.mit.edu	37	8	14412245	14412245	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr8:14412245G>A	uc003wwq.3	-	1	890	c.230C>T	c.(229-231)aCt>aTt	p.T77I	SGCZ_uc010lss.3_Missense_Mutation_p.T64I	NM_139167	NP_631906	Q96LD1	SGCZ_HUMAN	Homo sapiens sarcoglycan, zeta (SGCZ), mRNA.	64					cytoskeleton organization	cytoplasm|cytoskeleton|integral to membrane|sarcolemma		p.T77T(1)		NS(1)|central_nervous_system(2)|endometrium(1)|kidney(3)|large_intestine(14)|lung(15)|ovary(2)|prostate(3)|skin(5)|upper_aerodigestive_tract(1)	47				all cancers(2;0.000643)|Colorectal(111;0.00674)|COAD - Colon adenocarcinoma(73;0.0193)|GBM - Glioblastoma multiforme(2;0.026)		ACTTACCACAGTGAAATTCAT	0.328000														22			16		0	0	0.004007	0	0
DTX2	113878	broad.mit.edu	37	7	76112398	76112398	+	Missense_Mutation	SNP	G	A	A	rs142155908	byFrequency	TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr7:76112398G>A	uc011kgk.1	+	2	921	c.569G>A	c.(568-570)cGc>cAc	p.R190H	DTX2_uc003uff.4_Missense_Mutation_p.R281H|DTX2_uc003ufg.4_Missense_Mutation_p.R281H|DTX2_uc003ufh.4_Missense_Mutation_p.R281H|DTX2_uc003ufj.4_Missense_Mutation_p.R281H	NM_020892	NP_065943	Q86UW9	DTX2_HUMAN	Homo sapiens deltex homolog 2 (Drosophila) (DTX2), transcript variant 1, mRNA.	281					Notch signaling pathway	cytoplasm|nucleus	protein binding|zinc ion binding			NS(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(14)|ovary(1)|skin(1)|stomach(2)	27						CCCCTCTACCGCTCCAGCCTC	0.682000														64			8		0	0	0.002450	0	0
KRTAP4-8	728224	broad.mit.edu	37	17	39254054	39254054	+	Missense_Mutation	SNP	A	T	T	rs76270529	by1000genomes	TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr17:39254054A>T	uc010wfo.2	-	0	322	c.283T>A	c.(283-285)Tgc>Agc	p.C95S		NM_031960	NP_114166	Q9BYQ9	KRA48_HUMAN	Homo sapiens keratin associated protein 4-8 (KRTAP4-8), mRNA.	95	25 X 5 AA repeats of C-C-[IKRQVHEC]- [SPRT]-[STCVQPR].					keratin filament		p.C95S(8)		endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|lung(1)|prostate(1)	11						ctggagatgcagcagcTAGGG	0.677000														28			5		0	0	0.000602	0	0
PDZD2	23037	broad.mit.edu	37	5	32058048	32058048	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr5:32058048C>T	uc003jhl.3	+	11	2427	c.2039C>T	c.(2038-2040)cCc>cTc	p.P680L	PDZD2_uc003jhm.3_Missense_Mutation_p.P680L|PDZD2_uc011cnx.1_Missense_Mutation_p.P506L	NM_178140	NP_835260	O15018	PDZD2_HUMAN	Homo sapiens PDZ domain containing 2 (PDZD2), mRNA.	680					cell adhesion	cell-cell junction|endoplasmic reticulum|extracellular region|nucleus				NS(2)|breast(4)|central_nervous_system(5)|cervix(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(31)|lung(58)|ovary(6)|prostate(2)|skin(8)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	148						AGCCTCACACCCTGCTCGACA	0.532000											OREG0016543	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		9			13		0	0	0.003163	0	0
NPSR1	387129	broad.mit.edu	37	7	34698172	34698172	+	Splice_Site	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr7:34698172G>A	uc003teh.1	+	1	275	c.147_splice	c.e1+1	p.K49_splice	NPSR1-AS1_uc010kwo.2_Intron|NPSR1-AS1_uc010kwp.2_Intron|NPSR1-AS1_uc003tdz.3_Intron|NPSR1-AS1_uc010kwq.2_Intron|NPSR1-AS1_uc003teb.1_Intron|NPSR1-AS1_uc011kaq.1_Intron|NPSR1_uc003teg.1_Splice_Site_p.K49_splice|NPSR1_uc010kwt.1_Splice_Site|NPSR1_uc010kwu.1_Splice_Site|NPSR1_uc010kwv.1_Splice_Site_p.K49_splice|NPSR1_uc003tei.1_Splice_Site_p.K49_splice|NPSR1_uc010kww.1_Splice_Site_p.K49_splice|NPSR1_uc011kar.1_Splice_Site_p.K49_splice	NM_207173	NP_997056	Q6W5P4	NPSR1_HUMAN	Homo sapiens neuropeptide S receptor 1 (NPSR1), transcript variant 2, mRNA.	49						cytoplasm|integral to membrane|plasma membrane	vasopressin receptor activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(5)|lung(14)|pancreas(1)|skin(7)	31					Halothane(DB01159)	CTCCTTTAAGGTAAGTTTCTT	0.438000														32			29		0	0	0.006320	0	0
RARS	5917	broad.mit.edu	37	5	167915736	167915736	+	Nonsense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr5:167915736C>T	uc003lzx.3	+	1	216	c.175C>T	c.(175-177)Cga>Tga	p.R59*	RARS_uc011deo.2_5'UTR	NM_002887	NP_002878	P54136	SYRC_HUMAN	Homo sapiens arginyl-tRNA synthetase (RARS), mRNA.	59	Could be involved in the assembly of the multisynthetase complex.				arginyl-tRNA aminoacylation	cytosol|nucleus|soluble fraction	ATP binding|arginine-tRNA ligase activity|protein binding	p.R59*(2)		breast(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(11)|ovary(2)|skin(1)|stomach(1)	22	Renal(175;0.000159)|Lung NSC(126;0.0875)|all_lung(126;0.166)	Medulloblastoma(196;0.0208)|all_neural(177;0.0227)	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.0693)|Epithelial(171;0.131)|OV - Ovarian serous cystadenocarcinoma(192;0.156)		GAATATTCTTCGAAAGGTGAG	0.338000														30			20		0	0	0.012319	0	0
PAMR1	25891	broad.mit.edu	37	11	35454298	35454298	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr11:35454298G>A	uc001mwf.3	-	11	1863	c.1820C>T	c.(1819-1821)tCc>tTc	p.S607F	PAMR1_uc001mwg.3_Missense_Mutation_p.S590F|PAMR1_uc010rew.2_Missense_Mutation_p.S479F|PAMR1_uc010rex.2_Missense_Mutation_p.S550F	NM_015430	NP_056245	Q6UXH9	PAMR1_HUMAN	Homo sapiens peptidase domain containing associated with muscle regeneration 1 (PAMR1), transcript variant 1, mRNA.	590	Peptidase S1.				proteolysis	extracellular region	serine-type endopeptidase activity			breast(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(6)|lung(8)|ovary(3)|upper_aerodigestive_tract(1)	26						CTCCTGGAAGGAAGTGCTGAG	0.597000														5			18		0	0	0.006122	0	0
PTPRD	5789	broad.mit.edu	37	9	8486101	8486101	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr9:8486101C>T	uc003zkk.3	-	27	3459	c.2716G>A	c.(2716-2718)Gag>Aag	p.E906K	PTPRD_uc003zkp.3_Intron|PTPRD_uc003zkq.3_Intron|PTPRD_uc003zkr.3_Intron|PTPRD_uc003zks.3_Intron|PTPRD_uc022bdj.1_Intron	NM_002839	NP_002830	P23468	PTPRD_HUMAN	Homo sapiens protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 1, mRNA.	906	Fibronectin type-III 6.				transmembrane receptor protein tyrosine phosphatase signaling pathway	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity			NS(1)|breast(7)|central_nervous_system(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(22)|liver(1)|lung(83)|ovary(4)|pancreas(1)|prostate(7)|skin(19)|stomach(3)|upper_aerodigestive_tract(5)|urinary_tract(1)	168		all_cancers(3;3.38e-95)|all_epithelial(3;2.84e-91)|all_lung(3;7.3e-56)|Lung NSC(3;1.82e-52)|Renal(3;3.42e-19)|all_hematologic(3;0.000134)|all_neural(3;0.00409)|Acute lymphoblastic leukemia(23;0.0069)|Melanoma(3;0.0121)|Myeloproliferative disorder(4;0.0122)|Medulloblastoma(3;0.0144)|Lung SC(3;0.0301)|Ovarian(56;0.0694)|Hepatocellular(3;0.0824)		all cancers(1;3.38e-12)|Epithelial(1;2.12e-09)|STAD - Stomach adenocarcinoma(1;1.29e-07)|KIRC - Kidney renal clear cell carcinoma(3;5.49e-07)|Kidney(3;6.36e-07)|GBM - Glioblastoma multiforme(50;9.05e-05)|Lung(1;0.000189)|BRCA - Breast invasive adenocarcinoma(1;0.00178)|LUSC - Lung squamous cell carcinoma(1;0.0115)|LUAD - Lung adenocarcinoma(58;0.119)		TTCACCATCTCCTCCCCAAAG	0.468000										TSP Lung(15;0.13)				6			23		0	0	0.002780	0	0
FREM1	158326	broad.mit.edu	37	9	14841567	14841567	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr9:14841567G>A	uc003zlm.3	-	10	2575	c.1759C>T	c.(1759-1761)Ctt>Ttt	p.L587F	FREM1_uc010mic.3_Non-coding_Transcript	NM_144966	NP_659403	Q5H8C1	FREM1_HUMAN	Homo sapiens FRAS1 related extracellular matrix 1 (FREM1), transcript variant 1, mRNA.	587					cell communication|multicellular organismal development	basement membrane|integral to membrane	metal ion binding|sugar binding			breast(3)|cervix(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(23)|lung(40)|ovary(4)|pancreas(1)|prostate(4)|skin(2)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	100				GBM - Glioblastoma multiforme(50;3.53e-06)		TCCCTCTGAAGGAAGCCATGG	0.383000														21			60		0	0	0.014410	0	0
PRAMEF11	440560	broad.mit.edu	37	1	12887488	12887488	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr1:12887488G>A	uc001auk.2	-	2	565	c.369C>T	c.(367-369)taC>taT	p.Y123Y		NM_001146344	NP_001139816	O60813	PRA11_HUMAN	Homo sapiens PRAME family member 11 (PRAMEF11), mRNA.	123										NS(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|lung(7)|pancreas(2)|skin(4)|urinary_tract(1)	27						GGCAGGTGAGGTATTCATCCA	0.473000														39			4		0	0	0.003080	0	0
CDKN2A	1029	broad.mit.edu	37	9	21971208	21971208	+	Splice_Site	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr9:21971208C>T	uc003zpk.3	-	2	457	c.151_splice	c.e2-1	p.V51_splice	MTAP_uc003zpi.1_Intron|CDKN2A_uc003zpj.3_Splice_Site|CDKN2A_uc010miu.3_Splice_Site_p.V51_splice|CDKN2A_uc003zpl.3_Splice_Site_p.G65_splice	NM_000077	NP_000068	P42771	CD2A1_HUMAN	Homo sapiens cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) (CDKN2A), transcript variant 1, mRNA.	51					G1 phase of mitotic cell cycle|G1/S transition of mitotic cell cycle|Ras protein signal transduction|cell cycle arrest|cell cycle checkpoint|induction of apoptosis|negative regulation of NF-kappaB transcription factor activity|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of cell-matrix adhesion|negative regulation of cyclin-dependent protein kinase activity|positive regulation of macrophage apoptosis|positive regulation of smooth muscle cell apoptosis|replicative senescence	cytosol|nucleus	NF-kappaB binding|cyclin-dependent protein kinase inhibitor activity|protein binding|protein kinase binding	p.0?(1315)|p.?(38)|p.0(1)|p.V28_V51del(1)		NS(28)|adrenal_gland(6)|autonomic_ganglia(11)|biliary_tract(74)|bone(84)|breast(46)|central_nervous_system(522)|cervix(23)|endometrium(14)|eye(4)|genital_tract(15)|haematopoietic_and_lymphoid_tissue(698)|kidney(39)|large_intestine(11)|liver(92)|lung(365)|meninges(18)|oesophagus(239)|ovary(98)|pancreas(263)|pleura(94)|prostate(13)|salivary_gland(10)|skin(541)|small_intestine(1)|soft_tissue(93)|stomach(48)|thymus(4)|thyroid(24)|upper_aerodigestive_tract(436)|urinary_tract(283)|vulva(2)	4199		all_cancers(5;0)|Acute lymphoblastic leukemia(3;0)|all_hematologic(3;0)|all_epithelial(2;2.37e-290)|Lung NSC(2;1.26e-139)|all_lung(2;4.48e-131)|Glioma(2;3.26e-60)|all_neural(2;2.1e-52)|Renal(3;1.07e-46)|Esophageal squamous(3;3.83e-46)|Melanoma(2;2.74e-34)|Breast(3;1.14e-11)|Ovarian(3;0.000128)|Hepatocellular(5;0.00162)|Colorectal(97;0.172)		all cancers(2;0)|GBM - Glioblastoma multiforme(3;0)|Lung(2;4.07e-74)|Epithelial(2;1.08e-61)|LUSC - Lung squamous cell carcinoma(2;3.82e-48)|LUAD - Lung adenocarcinoma(2;4.56e-26)|OV - Ovarian serous cystadenocarcinoma(39;7.64e-10)|BRCA - Breast invasive adenocarcinoma(2;5.01e-09)|STAD - Stomach adenocarcinoma(4;4.63e-07)|Kidney(2;5.79e-07)|KIRC - Kidney renal clear cell carcinoma(2;7.27e-07)|COAD - Colon adenocarcinoma(8;5.15e-05)		TCATCATGACCTGCCAGAGAG	0.667000		17								HNSCC(2;<9.43e_08)|TSP Lung(5;3.83e-07)				19			24		0	0	0.003954	0	0
PLXDC2	84898	broad.mit.edu	37	10	20466284	20466284	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr10:20466284C>T	uc001iqg.1	+	8	1644	c.1007C>T	c.(1006-1008)cCc>cTc	p.P336L	PLXDC2_uc001iqh.1_Missense_Mutation_p.P287L|PLXDC2_uc009xkc.1_Non-coding_Transcript	NM_032812	NP_116201	Q6UX71	PXDC2_HUMAN	Homo sapiens plexin domain containing 2 (PLXDC2), mRNA.	336	PSI.					integral to membrane		p.P336P(1)		breast(1)|central_nervous_system(1)|endometrium(4)|kidney(3)|large_intestine(9)|liver(1)|lung(9)|ovary(2)|skin(3)|stomach(1)	34						AGATGTGGCCCCTGTGTATCT	0.363000														8			37		0	0	0.009718	0	0
GLDN	342035	broad.mit.edu	37	15	51676081	51676081	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr15:51676081G>A	uc002aba.3	+	3	702	c.533G>A	c.(532-534)gGa>gAa	p.G178E	GLDN_uc010bez.1_Missense_Mutation_p.E161K|GLDN_uc002abb.3_Missense_Mutation_p.G54E	NM_181789	NP_861454	Q6ZMI3	GLDN_HUMAN	Homo sapiens gliomedin (GLDN), mRNA.	178	Collagen-like 1.				cell differentiation|nervous system development	collagen|integral to membrane|plasma membrane				central_nervous_system(1)|kidney(2)|large_intestine(4)|lung(6)|ovary(2)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	19				all cancers(107;0.00194)|GBM - Glioblastoma multiforme(94;0.00942)		GGAAAAAGAGGAAAAATGGGT	0.483000														27			13		0	0	0.013537	0	0
BAHCC1	57597	broad.mit.edu	37	17	79409801	79409801	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr17:79409801C>T	uc002kaf.2	+	3	1240	c.1240C>T	c.(1240-1242)Ccc>Tcc	p.P414S	BAHCC1_uc002kae.2_5'Flank	NM_001080519	NP_001073988	Q9P281	BAHC1_HUMAN	Homo sapiens BAH domain and coiled-coil containing 1 (BAHCC1), mRNA.	476							DNA binding			breast(3)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(7)|ovary(1)|prostate(5)|urinary_tract(1)	26	all_neural(118;0.0804)|Melanoma(429;0.242)		BRCA - Breast invasive adenocarcinoma(99;0.0224)|OV - Ovarian serous cystadenocarcinoma(97;0.116)			CAGCGCAGGCCCCGAGGCCTC	0.667000														8			9		0	0	0.006214	0	0
GRIN2A	2903	broad.mit.edu	37	16	9923387	9923387	+	Missense_Mutation	SNP	A	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr16:9923387A>T	uc010uym.2	-	9	2210	c.1900T>A	c.(1900-1902)Tgg>Agg	p.W634R	GRIN2A_uc002czo.4_Missense_Mutation_p.W634R|GRIN2A_uc010uyn.2_Missense_Mutation_p.W477R|GRIN2A_uc002czr.4_Missense_Mutation_p.W634R	NM_000833	NP_001127879	Q12879	NMDE1_HUMAN	Homo sapiens glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A), transcript variant 2, mRNA.	634					response to ethanol	N-methyl-D-aspartate selective glutamate receptor complex|cell junction|outer membrane-bounded periplasmic space|postsynaptic membrane	N-methyl-D-aspartate selective glutamate receptor activity|zinc ion binding			NS(7)|breast(5)|cervix(1)|endometrium(11)|kidney(6)|large_intestine(36)|lung(71)|ovary(4)|prostate(9)|skin(45)|upper_aerodigestive_tract(2)|urinary_tract(1)	198					Felbamate(DB00949)|Glycine(DB00145)|L-Glutamic Acid(DB00142)|Loperamide(DB00836)|Memantine(DB01043)	AAGAAGGCCCATACAGATACC	0.493000														36			34		0	0	0.010818	0	0
HOXA11	3207	broad.mit.edu	37	7	27222434	27222434	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr7:27222434G>A	uc003syx.3	-	1	995	c.923C>T	c.(922-924)tCa>tTa	p.S308L	HOXA9_uc022aar.1_5'Flank|HOXA10_uc003syw.4_5'Flank|HOXA11_uc003syy.3_Non-coding_Transcript|HOXA11-AS_uc003syz.1_5'Flank	NM_005523	NP_005514	P31270	HXA11_HUMAN	Homo sapiens homeobox A11 (HOXA11), mRNA.	308					branching involved in ureteric bud morphogenesis|cartilage development involved in endochondral bone morphogenesis|developmental growth|dorsal/ventral pattern formation|mesodermal cell fate specification|positive regulation of cell development|positive regulation of chondrocyte differentiation	protein-DNA complex|transcription factor complex	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			NS(1)|breast(1)|endometrium(1)|large_intestine(2)|lung(8)|ovary(1)|skin(2)	16						TGGATTTGCTGAGTAGTACTG	0.443000			T	NUP98	CML									49			27		0	0	0.008361	0	0
ACAP1	9744	broad.mit.edu	37	17	7251257	7251257	+	Missense_Mutation	SNP	T	C	C	rs143351258		TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr17:7251257T>C	uc002ggd.2	+	14	1566	c.1360T>C	c.(1360-1362)Ttc>Ctc	p.F454L		NM_014716	NP_055531	Q15027	ACAP1_HUMAN	Homo sapiens ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (ACAP1), mRNA.	454	Arf-GAP.|Required for interaction with GULP1.				intracellular signal transduction|lipid metabolic process|protein transport|regulation of ARF GTPase activity		ARF GTPase activator activity|phospholipase C activity|protein binding|zinc ion binding			NS(1)|breast(5)|cervix(3)|endometrium(4)|kidney(1)|large_intestine(7)|liver(1)|lung(6)|prostate(3)|skin(1)|urinary_tract(1)	33						TGGTGTTCACTTCTCCAAAGT	0.597000														64			11		0	0	0.013537	0	0
ECEL1	9427	broad.mit.edu	37	2	233344912	233344912	+	Missense_Mutation	SNP	C	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr2:233344912C>A	uc002vsv.2	-	17	2484	c.2279G>T	c.(2278-2280)tGt>tTt	p.C760F	ECEL1_uc010fya.1_Missense_Mutation_p.C758F|ECEL1_uc010fyb.1_Missense_Mutation_p.C467F	NM_004826	NP_004817	O95672	ECEL1_HUMAN	Homo sapiens endothelin converting enzyme-like 1 (ECEL1), mRNA.	760					neuropeptide signaling pathway|proteolysis	integral to plasma membrane	metal ion binding|metalloendopeptidase activity			breast(1)|central_nervous_system(2)|endometrium(2)|kidney(1)|large_intestine(4)|lung(8)|ovary(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	23		all_hematologic(139;0.00793)|Renal(207;0.0112)|Acute lymphoblastic leukemia(138;0.0182)|all_lung(227;0.0449)|Lung NSC(271;0.132)		Epithelial(121;7.17e-17)|BRCA - Breast invasive adenocarcinoma(100;0.000771)|Lung(119;0.00213)|LUSC - Lung squamous cell carcinoma(224;0.00746)		GTCCTTGGGACAGTGGAAAGC	0.652000														31			12		0.000151284	0.000450635	0.001855	1	0
TCF3	6929	broad.mit.edu	37	19	1632113	1632113	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr19:1632113G>A	uc002ltr.3	-	4	291	c.222C>T	c.(220-222)acC>acT	p.T74T	TCF3_uc002ltt.4_Silent_p.T74T|TCF3_uc002ltq.3_Intron|TCF3_uc002lts.1_5'Flank	NM_003200	NP_003191	P15923	TFE2_HUMAN	Homo sapiens transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3), transcript variant 1, mRNA.	74				FDPSRTFSEGTHFTESHSSLSSSTFLGPGLG -> GGGECL AWCGPSAVHRCADVGLGMVSARTAP (in Ref. 6; CAA36297).	B cell lineage commitment|G1 phase of mitotic cell cycle|immunoglobulin V(D)J recombination|muscle cell differentiation|positive regulation of B cell proliferation|positive regulation of cell cycle|positive regulation of muscle cell differentiation|positive regulation of neuron differentiation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription from RNA polymerase II promoter	cytoplasm|nucleus|protein complex|transcription factor complex	DNA binding|E-box binding|bHLH transcription factor binding|identical protein binding|mitogen-activated protein kinase kinase kinase binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|vitamin D response element binding			breast(2)|central_nervous_system(1)|kidney(2)|large_intestine(2)|lung(6)|ovary(1)|skin(2)	16		Acute lymphoblastic leukemia(61;5.94e-12)|all_hematologic(61;1.27e-07)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CCTCGCTGAAGGTCTAGGGGA	0.637000			T	"""PBX1, HLF, TFPT"""	pre B-ALL									16			6		0	0	0.003080	0	0
TAS2R60	338398	broad.mit.edu	37	7	143141184	143141184	+	Missense_Mutation	SNP	G	A	A	rs141559059		TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr7:143141184G>A	uc011ktg.2	+	0	639	c.639G>A	c.(637-639)atG>atA	p.M213I	LOC285965_uc003wda.3_Intron	NM_177437	NP_803186	P59551	T2R60_HUMAN	Homo sapiens taste receptor, type 2, member 60 (TAS2R60), mRNA.	213					sensory perception of bitter taste	integral to membrane	G-protein coupled receptor activity	p.M213I(4)		breast(1)|kidney(1)|large_intestine(2)|lung(17)|prostate(1)|skin(7)|urinary_tract(2)	31	Melanoma(164;0.172)					TCATTTGCATGATTTTGCTCA	0.463000														74			41		0	0	0.010771	0	0
ZNF536	9745	broad.mit.edu	37	19	30936347	30936347	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr19:30936347G>A	uc002nsu.1	+	1	2016	c.1878G>A	c.(1876-1878)atG>atA	p.M626I	ZNF536_uc010edd.1_Missense_Mutation_p.M626I	NM_014717	NP_055532	O15090	ZN536_HUMAN	Homo sapiens zinc finger protein 536 (ZNF536), mRNA.	626					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	zinc ion binding			NS(3)|breast(6)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(22)|lung(119)|ovary(7)|prostate(4)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(3)	182	Esophageal squamous(110;0.0834)					CTGGGAACATGAAGGAGAAGC	0.597000														102			58		0	0	0.014410	0	0
NEIL3	55247	broad.mit.edu	37	4	178281684	178281684	+	Silent	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr4:178281684C>T	uc003iut.2	+	8	1605	c.1488C>T	c.(1486-1488)ggC>ggT	p.G496G		NM_018248	NP_060718	Q8TAT5	NEIL3_HUMAN	Homo sapiens nei endonuclease VIII-like 3 (E. coli) (NEIL3), mRNA.	496					base-excision repair|nucleotide-excision repair	nucleus	DNA N-glycosylase activity|DNA-(apurinic or apyrimidinic site) lyase activity|bubble DNA binding|damaged DNA binding|double-stranded DNA binding|single-stranded DNA binding|zinc ion binding			breast(1)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(4)|lung(14)|ovary(1)|prostate(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	29		Breast(14;6.27e-05)|Melanoma(52;0.00102)|Renal(120;0.00988)|Prostate(90;0.00996)|all_hematologic(60;0.014)|all_neural(102;0.164)		all cancers(43;1.96e-23)|Epithelial(43;2.52e-20)|OV - Ovarian serous cystadenocarcinoma(60;1.89e-11)|GBM - Glioblastoma multiforme(59;9.49e-05)|Colorectal(24;0.00013)|COAD - Colon adenocarcinoma(29;0.000696)|STAD - Stomach adenocarcinoma(60;0.00308)|LUSC - Lung squamous cell carcinoma(193;0.0398)|READ - Rectum adenocarcinoma(43;0.191)		TGACAGATGGCCCTCGTACCT	0.478000								Base excision repair (BER), DNA glycosylases						8			21		0	0	0.003954	0	0
VARS	7407	broad.mit.edu	37	6	31759398	31759399	+	Missense_Mutation	DNP	GG	AA	AA			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr6:31759398_31759399GG>AA	uc003nxe.3	-	7	1511_1512	c.1088_1089CC>TT	c.(1087-1089)tcc>tTT	p.S363F	VARS_uc011doi.1_Non-coding_Transcript	NM_006295	NP_006286	P26640	SYVC_HUMAN	Homo sapiens valyl-tRNA synthetase (VARS), nuclear gene encoding mitochondrial protein, mRNA.	363					translational elongation|valyl-tRNA aminoacylation	cytosol	ATP binding|protein binding|valine-tRNA ligase activity			central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(18)|ovary(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)	30					L-Valine(DB00161)	ATCGAGTCAGGGAGTCCTGGAT	0.594000														180			96		0	0	0.004672	0	0
USH1C	10083	broad.mit.edu	37	11	17547910	17547910	+	Missense_Mutation	SNP	G	C	C			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr11:17547910G>C	uc001mnf.3	-	7	767	c.658C>G	c.(658-660)Cga>Gga	p.R220G	USH1C_uc001mne.3_Missense_Mutation_p.R220G|USH1C_uc009yhb.3_Missense_Mutation_p.R220G|USH1C_uc001mng.3_Non-coding_Transcript|USH1C_uc001mnd.3_Missense_Mutation_p.R184G	NM_005709	NP_005700	Q9Y6N9	USH1C_HUMAN	Homo sapiens Usher syndrome 1C (autosomal recessive, severe) (USH1C), transcript variant 1, mRNA.	220	PDZ 2.				G2/M transition of mitotic cell cycle|equilibrioception|photoreceptor cell maintenance|sensory perception of sound	apical part of cell|cytoplasm|stereocilium	protein binding			central_nervous_system(2)|endometrium(3)|kidney(2)|large_intestine(9)|lung(25)|ovary(1)|prostate(3)|skin(1)|stomach(1)|urinary_tract(1)	48						CCAAGGCCTCGGGAGCCTACC	0.617000														5			9		0	0	0.006214	0	0
IZUMO2	126123	broad.mit.edu	37	19	50657868	50657868	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr19:50657868G>A	uc002prp.1	-	5	699	c.612C>T	c.(610-612)gtC>gtT	p.V204V		NM_152358	NP_689571	Q6UXV1	IZUM2_HUMAN	Homo sapiens IZUMO family member 2 (IZUMO2), mRNA.	204						integral to membrane				cervix(1)|endometrium(1)|kidney(1)|large_intestine(1)|lung(2)|prostate(1)	7						AGACCACGATGACCACGAAGA	0.587000														41			30		0	0	0.007291	0	0
IL9R	3581	broad.mit.edu	37	X	155233493	155233493	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chrX:155233493G>A	uc004fnv.1	+	3	585	c.406G>A	c.(406-408)Gac>Aac	p.D136N	IL9R_uc010nvn.2_Missense_Mutation_p.D115N|IL9R_uc004fnu.1_Nonsense_Mutation_p.W180*	NM_002186	NP_002177	Q01113	IL9R_HUMAN	Homo sapiens interleukin 9 receptor (IL9R), transcript variant 1, mRNA.	136					cell proliferation	extracellular space|integral to plasma membrane	interleukin-9 receptor activity			NS(1)|central_nervous_system(1)|cervix(2)|endometrium(2)|kidney(3)|large_intestine(1)|lung(12)|upper_aerodigestive_tract(1)	23	all_cancers(53;1.86e-17)|all_epithelial(53;2.71e-11)|all_lung(58;1.84e-07)|Lung NSC(58;5.62e-07)|all_hematologic(71;2.45e-06)|Acute lymphoblastic leukemia(192;6.56e-05)|Breast(217;0.176)|Renal(33;0.214)					CAGCCTGGTGGACCCGGAGTA	0.622000														61			25		0	0	0.009535	0	0
C1orf129	80133	broad.mit.edu	37	1	170959135	170959135	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr1:170959135C>T	uc010plz.2	+	10	1173	c.1019C>T	c.(1018-1020)cCa>cTa	p.P340L	C1orf129_uc001ghg.3_Missense_Mutation_p.P340L|C1orf129_uc009wvy.3_Missense_Mutation_p.P147L	NM_001163629	NP_001157101	Q5TGP6	CA129_HUMAN	Homo sapiens chromosome 1 open reading frame 129 (C1orf129), transcript variant 1, mRNA.	340							binding			breast(2)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(12)|lung(16)|pancreas(1)|prostate(1)|skin(3)	45	all_hematologic(923;0.0922)|Acute lymphoblastic leukemia(37;0.181)					TACCCAGTTCCAGCAGACGAG	0.473000														17			16		0	0	0.007413	0	0
HMGCS2	3158	broad.mit.edu	37	1	120293428	120293428	+	Silent	SNP	G	C	C			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr1:120293428G>C	uc001eid.3	-	8	1612	c.1524C>G	c.(1522-1524)gtC>gtG	p.V508V	HMGCS2_uc010oxj.2_Silent_p.V466V|HMGCS2_uc021osw.1_Silent_p.V274V	NM_005518	NP_005509	P54868	HMCS2_HUMAN	Homo sapiens 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (HMGCS2), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.	508					acetoacetic acid biosynthetic process|cholesterol biosynthetic process|isoprenoid biosynthetic process|ketone body biosynthetic process	mitochondrial matrix	hydroxymethylglutaryl-CoA synthase activity			NS(1)|breast(2)|endometrium(2)|kidney(2)|large_intestine(1)|lung(13)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	28	all_cancers(5;6.38e-10)|all_epithelial(5;1.1e-10)|Melanoma(3;1.93e-05)|Breast(55;0.218)|all_neural(166;0.219)	all_lung(203;1.29e-06)|Lung NSC(69;9.35e-06)|all_epithelial(167;0.00124)		Lung(183;0.0112)|LUSC - Lung squamous cell carcinoma(189;0.0595)		ACCACCTTTAGACGGGACGCC	0.537000														712			238		0	0	0.014410	0	0
HDAC6	10013	broad.mit.edu	37	X	48681101	48681101	+	Silent	SNP	A	C	C			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chrX:48681101A>C	uc011mmi.1	+	23	2504	c.2409A>C	c.(2407-2409)ccA>ccC	p.P803P	HDAC6_uc004dks.1_Silent_p.P803P|HDAC6_uc010nig.1_Silent_p.P651P|HDAC6_uc004dkt.1_Silent_p.P803P|HDAC6_uc011mmk.1_Silent_p.P784P|HDAC6_uc004dkv.1_Silent_p.P451P|HDAC6_uc004dkw.1_Silent_p.P451P|HDAC6_uc004dkx.1_Silent_p.P166P	NM_006044	NP_006035	Q9UBN7	HDAC6_HUMAN	Homo sapiens histone deacetylase 6 (HDAC6), mRNA.	803					Hsp90 deacetylation|aggresome assembly|cellular response to hydrogen peroxide|lysosome localization|macroautophagy|misfolded or incompletely synthesized protein catabolic process|negative regulation of proteolysis|negative regulation of transcription, DNA-dependent|peptidyl-lysine deacetylation|polyubiquitinated misfolded protein transport|positive regulation of apoptosis|positive regulation of cellular chaperone-mediated protein complex assembly|positive regulation of epithelial cell migration|positive regulation of receptor biosynthetic process|positive regulation of signal transduction|regulation of androgen receptor signaling pathway|regulation of receptor activity|response to growth factor stimulus|response to toxin|transcription, DNA-dependent|tubulin deacetylation	aggresome|caveola|cell leading edge|cytosol|histone deacetylase complex|microtubule associated complex|perinuclear region of cytoplasm	Hsp90 protein binding|NAD-dependent histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|actin binding|alpha-tubulin binding|beta-catenin binding|dynein complex binding|histone deacetylase activity (H3-K16 specific)|histone deacetylase binding|microtubule binding|polyubiquitin binding|tau protein binding|tubulin deacetylase activity|zinc ion binding	p.P803P(4)		breast(2)|endometrium(6)|kidney(5)|large_intestine(8)|lung(9)|ovary(3)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	40					Vorinostat(DB02546)	GAGACCCACCACCCCTGCTGA	0.587000														28			6		0	0	0.013537	0	0
BMP2K	55589	broad.mit.edu	37	4	79793862	79793862	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr4:79793862C>T	uc003hlk.3	+	12	1869	c.1703C>T	c.(1702-1704)cCt>cTt	p.P568L	BMP2K_uc003hlj.3_Missense_Mutation_p.P568L|BMP2K_uc003hll.3_Missense_Mutation_p.P32L	NM_198892	NP_942595	Q9NSY1	BMP2K_HUMAN	Homo sapiens BMP2 inducible kinase (BMP2K), transcript variant 1, mRNA.	568						nucleus	ATP binding|protein serine/threonine kinase activity			NS(1)|breast(1)|endometrium(4)|large_intestine(2)|lung(3)|prostate(1)|urinary_tract(1)	13						CTTACCTCCCCTCAAGAGTTC	0.463000														9			29		0	0	0.005443	0	0
DDX12P	440081	broad.mit.edu	37	12	9580280	9580280	+	RNA	SNP	A	G	G	rs146037854	by1000genomes	TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr12:9580280A>G	uc021qut.1	-	4		c.342T>C			DDX12P_uc001qvx.4_Non-coding_Transcript					Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene (DDX12P), non-coding RNA.																		AGTCGTTGATAGTCTTCAGCT	0.493000														96			7		0	0	0.003080	0	0
PREX2	80243	broad.mit.edu	37	8	68972998	68972998	+	Silent	SNP	T	C	C			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr8:68972998T>C	uc003xxv.1	+	10	1350	c.1323T>C	c.(1321-1323)aaT>aaC	p.N441N	PREX2_uc003xxu.1_Silent_p.N441N|PREX2_uc011lez.1_Silent_p.N376N	NM_024870	NP_079146	Q70Z35	PREX2_HUMAN	Homo sapiens phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 (PREX2), transcript variant 1, mRNA.	441	DEP 1.				G-protein coupled receptor protein signaling pathway|intracellular signal transduction	intracellular	Rac GTPase activator activity|Rac guanyl-nucleotide exchange factor activity|protein binding			NS(6)|biliary_tract(1)|breast(4)|endometrium(11)|kidney(16)|large_intestine(25)|liver(4)|lung(57)|ovary(2)|pancreas(4)|prostate(3)|skin(42)|upper_aerodigestive_tract(1)|urinary_tract(2)	178						TATTAGAAAATGGAATCATTC	0.348000														67			13		0	0	0.013537	0	0
LLGL2	3993	broad.mit.edu	37	17	73567827	73567827	+	Silent	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr17:73567827C>T	uc002joh.3	+	17	2410	c.2256C>T	c.(2254-2256)gcC>gcT	p.A752A	LLGL2_uc002joi.3_Silent_p.A752A|LLGL2_uc010dgg.2_Silent_p.A752A|LLGL2_uc002joj.3_Silent_p.A741A|LLGL2_uc010wsd.2_Silent_p.A379A	NM_001031803	NP_001026973	Q6P1M3	L2GL2_HUMAN	Homo sapiens lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 3, mRNA.	752					cell cycle|cell division|exocytosis|regulation of establishment or maintenance of cell polarity	cytoplasm|intracellular membrane-bounded organelle	PDZ domain binding			NS(1)|breast(3)|cervix(2)|endometrium(2)|kidney(1)|large_intestine(2)|lung(9)|ovary(2)|pancreas(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(1)|urinary_tract(1)	31	all_cancers(13;3.15e-09)|all_epithelial(9;5.78e-10)|Breast(9;5.8e-10)|all_lung(278;0.246)		all cancers(21;1.8e-07)|Epithelial(20;1.38e-06)|Lung(188;0.0696)|LUSC - Lung squamous cell carcinoma(166;0.112)			TGCCTCCCGCCGAGCGGAGAA	0.682000														8			26		0	0	0.005443	0	0
DNMT1	1786	broad.mit.edu	37	19	10246815	10246815	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr19:10246815G>A	uc002mng.3	-	36	4770	c.4590C>T	c.(4588-4590)ccC>ccT	p.P1530P	DNMT1_uc002mnf.3_Silent_p.P454P|DNMT1_uc010xlc.2_Silent_p.P1546P|DNMT1_uc002mnh.3_Silent_p.P1425P|DNMT1_uc010xld.2_Silent_p.P1533P	NM_001379	NP_001370	P26358	DNMT1_HUMAN	Homo sapiens DNA (cytosine-5-)-methyltransferase 1 (DNMT1), transcript variant 2, mRNA.	1530	Catalytic.|Interaction with the PRC2/EED-EZH2 complex (By similarity).				chromatin modification|maintenance of DNA methylation|negative regulation of histone H3-K9 methylation|negative regulation of transcription from RNA polymerase II promoter|positive regulation of gene expression|positive regulation of histone H3-K4 methylation|transcription, DNA-dependent	nucleus	DNA (cytosine-5-)-methyltransferase activity|DNA binding|transcription factor binding	p.P1530L(1)		breast(5)|endometrium(8)|kidney(5)|large_intestine(21)|lung(11)|ovary(2)|pancreas(1)|prostate(10)|skin(5)|stomach(1)|urinary_tract(1)	70			OV - Ovarian serous cystadenocarcinoma(20;1.59e-09)|Epithelial(33;2.86e-06)|all cancers(31;6.68e-06)		Azacitidine(DB00928)|Decitabine(DB01262)|Flucytosine(DB01099)|Ifosfamide(DB01181)|Procainamide(DB01035)	CCATGGGCTCGGGGTTGGTGA	0.647000														32			27		0	0	0.008361	0	0
LOC440563	440563	broad.mit.edu	37	1	13183427	13183427	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr1:13183427G>A	uc010obg.2	-	1	689	c.446C>T	c.(445-447)tCa>tTa	p.S149L		NM_001136561	NP_001130033	B2RXH8	B2RXH8_HUMAN	Homo sapiens heterogeneous nuclear ribonucleoprotein C-like (LOC440563), mRNA.	149						ribonucleoprotein complex	nucleic acid binding|nucleotide binding										GGTGTTTCCTGATATGCGCTG	0.512000														209			77		0	0	0.014410	0	0
abParts	0	broad.mit.edu	37	14	106725137	106725137	+	RNA	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr14:106725137C>T	uc021ser.1	-	928		c.22341G>A								Parts of antibodies, mostly variable regions.																		CCGCTGATTTCCCCCCCATCG	0.587000														65			23		0	0	0.012319	0	0
ZNF334	55713	broad.mit.edu	37	20	45130161	45130161	+	Missense_Mutation	SNP	C	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr20:45130161C>A	uc002xsa.3	-	3	2348	c.1886G>T	c.(1885-1887)gGg>gTg	p.G629V	ZNF334_uc002xsb.3_Missense_Mutation_p.G568V|ZNF334_uc002xsd.3_Missense_Mutation_p.G568V|ZNF334_uc002xsc.3_Missense_Mutation_p.G606V|ZNF334_uc010ghl.3_Missense_Mutation_p.G605V			Q9HCZ1	ZN334_HUMAN	Homo sapiens zinc finger protein 334 (ZNF334), transcript variant 2, mRNA.	606					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(1)|breast(2)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(9)|lung(8)|ovary(1)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	32		Myeloproliferative disorder(115;0.0122)				GAAGGATTTCCCACATTCATT	0.423000														211			37		6.29468e-14	1.89517e-13	0.004878	1	0
HIVEP2	3097	broad.mit.edu	37	6	143093699	143093699	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr6:143093699G>A	uc003qjd.3	-	4	2920	c.2177C>T	c.(2176-2178)tCc>tTc	p.S726F		NM_006734	NP_006725	P31629	ZEP2_HUMAN	Homo sapiens human immunodeficiency virus type I enhancer binding protein 2 (HIVEP2), mRNA.	726					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(2)|breast(4)|central_nervous_system(6)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(19)|lung(35)|ovary(4)|prostate(6)|skin(4)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	100				OV - Ovarian serous cystadenocarcinoma(155;1.61e-05)|GBM - Glioblastoma multiforme(68;0.0102)		GTCATAATCGGAAGCCATGAT	0.522000														37			37		0	0	0.005524	0	0
PLXDC2	84898	broad.mit.edu	37	10	20432323	20432323	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr10:20432323C>T	uc001iqg.1	+	4	1278	c.641C>T	c.(640-642)tCa>tTa	p.S214L	PLXDC2_uc001iqh.1_Missense_Mutation_p.S165L|PLXDC2_uc009xkc.1_Non-coding_Transcript	NM_032812	NP_116201	Q6UX71	PXDC2_HUMAN	Homo sapiens plexin domain containing 2 (PLXDC2), mRNA.	214						integral to membrane				breast(1)|central_nervous_system(1)|endometrium(4)|kidney(3)|large_intestine(9)|liver(1)|lung(9)|ovary(2)|skin(3)|stomach(1)	34						TCCAGAAATTCAACTGTCAGA	0.358000														10			40		0	0	0.009718	0	0
IL1R1	3554	broad.mit.edu	37	2	102785060	102785060	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr2:102785060G>A	uc002tbq.3	+	6	976	c.658G>A	c.(658-660)Gaa>Aaa	p.E220K	IL1R1_uc010fix.3_Missense_Mutation_p.E220K|IL1R1_uc002tbr.3_Missense_Mutation_p.E220K	NM_000877	NP_000868	P14778	IL1R1_HUMAN	Homo sapiens interleukin 1 receptor, type I (IL1R1), mRNA.	220					innate immune response	integral to plasma membrane	interleukin-1, Type I, activating receptor activity|platelet-derived growth factor receptor binding			breast(2)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(4)|prostate(2)|skin(3)	19					Anakinra(DB00026)	TCTTTCAGAGGAAAACAAACC	0.428000														70			40		0	0	0.011902	0	0
ARHGAP11B	89839	broad.mit.edu	37	15	30938448	30938448	+	RNA	SNP	A	G	G	rs146574312	by1000genomes	TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr15:30938448A>G	uc010azv.1	+	10		c.1258A>G			ARHGAP11B_uc001zeu.3_Non-coding_Transcript|LOC100288637_uc001zev.3_Non-coding_Transcript			Q3KRB8	RHGBB_HUMAN	Homo sapiens Rho GTPase activating protein 11B (ARHGAP11B), mRNA.						regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity			endometrium(2)|kidney(1)|large_intestine(3)|lung(1)|prostate(1)	8		all_lung(180;2.71e-09)|Breast(32;0.00116)		all cancers(64;1.9e-15)|Epithelial(43;3.59e-12)|GBM - Glioblastoma multiforme(186;9e-05)|BRCA - Breast invasive adenocarcinoma(123;0.00177)|Lung(196;0.153)		CTATTTGTGCATGGTGGCTGG	0.483000														18			5		0	0	0.000602	0	0
CCDC170	80129	broad.mit.edu	37	6	151939193	151939193	+	Nonsense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr6:151939193C>T	uc003qol.3	+	10	2148	c.2059C>T	c.(2059-2061)Cag>Tag	p.Q687*	U6_uc021zgw.1_5'Flank	NM_025059	NP_079335	Q8IYT3	CF097_HUMAN	Homo sapiens chromosome 6 open reading frame 97 (C6orf97), mRNA.	687																	CCATTCACATCAGCATCACTT	0.473000														54			43		0	0	0.009718	0	0
STC1	6781	broad.mit.edu	37	8	23709033	23709033	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr8:23709033G>A	uc003xdw.1	-	2	557	c.273C>T	c.(271-273)ttC>ttT	p.F91F		NM_003155	NP_003146	P52823	STC1_HUMAN	Homo sapiens stanniocalcin 1 (STC1), mRNA.	91					cell surface receptor linked signaling pathway|cell-cell signaling|cellular calcium ion homeostasis		hormone activity			breast(1)|cervix(1)|endometrium(3)|large_intestine(4)|lung(9)|pancreas(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(1)	26		Prostate(55;0.055)|Breast(100;0.116)		Colorectal(74;0.0155)|COAD - Colon adenocarcinoma(73;0.0632)		TCTCTTTGACGAATGCTTTTC	0.507000														23			15		0	0	0.002450	0	0
FAM75A3	727830	broad.mit.edu	37	9	40702792	40702793	+	Missense_Mutation	DNP	CC	TT	TT			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr9:40702792_40702793CC>TT	uc010mmj.3	+	3	478_479	c.449_450CC>TT	c.(448-450)tcc>tTT	p.S150F		NM_001083124	NP_001076593	Q5VYP0	F75A3_HUMAN	Homo sapiens family with sequence similarity 75, member A3 (FAM75A3), mRNA.	150	Pro-rich.					integral to membrane				kidney(1)|large_intestine(2)|lung(18)|ovary(3)|prostate(1)|skin(1)	26				GBM - Glioblastoma multiforme(29;0.02)|Lung(182;0.0681)		CCCATTCTCTCCCTGTTAGCTT	0.599000														355			106		0	0	0.004672	0	0
CNTN5	53942	broad.mit.edu	37	11	100126527	100126527	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr11:100126527G>A	uc001pga.3	+	16	2545	c.2041G>A	c.(2041-2043)Gaa>Aaa	p.E681K	CNTN5_uc001pfz.3_Missense_Mutation_p.E681K|CNTN5_uc021qpb.1_Missense_Mutation_p.E681K|CNTN5_uc021qpc.1_Missense_Mutation_p.E607K|CNTN5_uc010ruk.2_5'UTR	NM_014361	NP_055176	O94779	CNTN5_HUMAN	Homo sapiens contactin 5 (CNTN5), transcript variant 1, mRNA.	681	Fibronectin type-III 1.				cell adhesion	anchored to membrane|plasma membrane	protein binding			NS(2)|breast(2)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(12)|lung(38)|ovary(2)|pancreas(2)|prostate(2)|skin(7)|upper_aerodigestive_tract(2)|urinary_tract(1)	81		all_hematologic(158;1.22e-05)|Acute lymphoblastic leukemia(157;3.81e-05)|Melanoma(852;0.219)		BRCA - Breast invasive adenocarcinoma(274;0.00146)|KIRC - Kidney renal clear cell carcinoma(183;0.156)|Kidney(183;0.196)		AATTGTTGAGGAAATAACCGA	0.478000														14			44		0	0	0.014410	0	0
MBD3	53615	broad.mit.edu	37	19	1578395	1578395	+	Missense_Mutation	SNP	C	G	G			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr19:1578395C>G	uc002ltj.3	-	5	842	c.820G>C	c.(820-822)Gac>Cac	p.D274H	AX747577_uc002lti.1_5'Flank|MBD3_uc002ltk.3_Missense_Mutation_p.D242H|MBD3_uc002ltl.1_Missense_Mutation_p.D274H	NM_003926	NP_003917	O95983	MBD3_HUMAN	Homo sapiens methyl-CpG binding domain protein 3 (MBD3), mRNA.	274	Poly-Glu.				transcription, DNA-dependent	NuRD complex	DNA binding|protein binding			central_nervous_system(1)|large_intestine(1)|lung(2)|ovary(1)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)	8		Acute lymphoblastic leukemia(61;3.02e-13)|all_hematologic(61;4.32e-09)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|Lung(535;0.179)|STAD - Stomach adenocarcinoma(1328;0.18)		tcctcctcgtcttcctcgtcg	0.716000														25			21		0	0	0.008871	0	0
MEPE	56955	broad.mit.edu	37	4	88767038	88767038	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr4:88767038G>A	uc021xpx.1	+	3	1123	c.1111G>A	c.(1111-1113)Gat>Aat	p.D371N	MEPE_uc021xpu.1_Missense_Mutation_p.D340N|MEPE_uc021xpv.1_Missense_Mutation_p.D227N|MEPE_uc021xpw.1_Missense_Mutation_p.D227N|MEPE_uc010ikn.3_Missense_Mutation_p.D227N|MEPE_uc003hqy.3_Missense_Mutation_p.D340N|MEPE_uc021xpy.1_Missense_Mutation_p.D227N	NM_001184697	NP_001171626	Q9NQ76	MEPE_HUMAN	Homo sapiens matrix extracellular phosphoglycoprotein (MEPE), transcript variant 5, mRNA.	340					skeletal system development	proteinaceous extracellular matrix	extracellular matrix structural constituent|protein binding	p.D340N(1)		cervix(1)|endometrium(1)|kidney(3)|large_intestine(5)|lung(19)|ovary(1)|skin(5)|upper_aerodigestive_tract(1)	36		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.000432)		GGGCAGCAACGATATCATGGG	0.473000														8			42		0	0	0.008740	0	0
FOXN2	3344	broad.mit.edu	37	2	48586205	48586205	+	Missense_Mutation	SNP	T	C	C			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr2:48586205T>C	uc002rwh.1	+	3	872	c.557T>C	c.(556-558)tTa>tCa	p.L186S		NM_002158	NP_002149	P32314	FOXN2_HUMAN	Homo sapiens forkhead box N2 (FOXN2), mRNA.	186					embryo development|pattern specification process|regulation of sequence-specific DNA binding transcription factor activity|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding			endometrium(1)|kidney(1)|large_intestine(3)|lung(5)|prostate(1)|skin(1)|urinary_tract(1)	13		all_hematologic(82;0.151)|Acute lymphoblastic leukemia(82;0.175)	Lung(47;0.0272)|LUSC - Lung squamous cell carcinoma(58;0.036)			AAAGGTTCCTTATGGTGTGTT	0.343000														19			13		0	0	0.003163	0	0
EEF1D	1936	broad.mit.edu	37	8	144671200	144671200	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr8:144671200C>T	uc003yyq.2	-	0	1431	c.1202G>A	c.(1201-1203)gGt>gAt	p.G401D	EEF1D_uc003yyp.2_Missense_Mutation_p.G351D|EEF1D_uc011lki.2_Intron|EEF1D_uc003yyv.3_Intron|EEF1D_uc003yyu.3_Intron|EEF1D_uc011lkk.2_Intron|EEF1D_uc003yyt.3_Missense_Mutation_p.G351D|EEF1D_uc003yyr.3_Missense_Mutation_p.G351D|EEF1D_uc003yys.3_Intron|EEF1D_uc011lkl.2_Intron	NM_032378	NP_115754	P29692	EF1D_HUMAN	Homo sapiens eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D), transcript variant 1, mRNA.	0					positive regulation of I-kappaB kinase/NF-kappaB cascade	cytosol|eukaryotic translation elongation factor 1 complex	protein binding|signal transducer activity|translation elongation factor activity			breast(2)|cervix(1)|endometrium(1)|kidney(4)|lung(2)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	14	all_cancers(97;3.74e-11)|all_epithelial(106;2.62e-09)|Lung NSC(106;0.00013)|all_lung(105;0.000374)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		Colorectal(110;0.134)|BRCA - Breast invasive adenocarcinoma(115;0.239)			AGACCGAGGACCGGGTCGGTG	0.692000														46			10		0	0	0.006214	0	0
NGEF	25791	broad.mit.edu	37	2	233834931	233834931	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr2:233834931C>T	uc002vts.2	-	2	624	c.376G>A	c.(376-378)Gaa>Aaa	p.E126K		NM_019850	NP_062824	Q8N5V2	NGEF_HUMAN	Homo sapiens neuronal guanine nucleotide exchange factor (NGEF), transcript variant 1, mRNA.	126	Regulatory region; modulates activity toward RHOA, RAC1 and CDC42 (By similarity).				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|nervous system development|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|growth cone|plasma membrane	Rho guanyl-nucleotide exchange factor activity			central_nervous_system(4)|endometrium(8)|kidney(2)|large_intestine(3)|lung(10)|ovary(3)|pancreas(1)|skin(4)	35		Breast(86;0.00279)|Renal(207;0.00339)|all_hematologic(139;0.00793)|Acute lymphoblastic leukemia(138;0.0182)|all_lung(227;0.0271)|Lung NSC(271;0.0839)		Epithelial(121;8.65e-17)|BRCA - Breast invasive adenocarcinoma(100;0.00037)|LUSC - Lung squamous cell carcinoma(224;0.00813)|Lung(119;0.00984)|GBM - Glioblastoma multiforme(43;0.0604)		TACCTCATTTCCTGGGCTCCT	0.498000														37			28		0	0	0.006320	0	0
KCNIP4	80333	broad.mit.edu	37	4	20734378	20734378	+	Missense_Mutation	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr4:20734378C>T	uc021xmt.1	-	6	688	c.568G>A	c.(568-570)Gat>Aat	p.D190N	KCNIP4_uc003gqe.2_Missense_Mutation_p.D173N|KCNIP4_uc003gqf.1_Missense_Mutation_p.D169N|KCNIP4_uc003gqg.1_Missense_Mutation_p.D128N|KCNIP4_uc003gqh.1_Missense_Mutation_p.D165N|KCNIP4_uc003gqi.1_Missense_Mutation_p.D128N|KCNIP4_uc021xmu.1_Missense_Mutation_p.D156N|PACRGL_uc003gpu.3_Intron|KCNIP4_uc021xms.1_Missense_Mutation_p.D153N	NM_025221	NP_671711	Q6PIL6	KCIP4_HUMAN	Homo sapiens Kv channel interacting protein 4 (KCNIP4), transcript variant 1, mRNA.	190	EF-hand 3.					plasma membrane	calcium ion binding|potassium channel activity|protein binding|voltage-gated ion channel activity			NS(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(6)|prostate(1)|upper_aerodigestive_tract(1)	13		Breast(46;0.134)				CCCATCATATCGTATATTGCT	0.378000														29			22		0	0	0.014323	0	0
OR9G4	283189	broad.mit.edu	37	11	56510999	56510999	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr11:56510999G>A	uc010rjo.2	-	0	289	c.289C>T	c.(289-291)Ctg>Ttg	p.L97L		NM_001005284	NP_001005284	Q8NGQ1	OR9G4_HUMAN	Homo sapiens olfactory receptor, family 9, subfamily G, member 4 (OR9G4), mRNA.	97					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|autonomic_ganglia(1)|endometrium(2)|kidney(2)|large_intestine(3)|liver(1)|lung(15)|ovary(2)|prostate(2)|skin(3)|stomach(1)|urinary_tract(1)	34						CAACTGGCCAGGATTTTGGGG	0.438000														83			52		0	0	0.014410	0	0
CTNND2	1501	broad.mit.edu	37	5	10992701	10992701	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr5:10992701G>A	uc003jfa.1	-	18	3318	c.3173C>T	c.(3172-3174)tCc>tTc	p.S1058F	CTNND2_uc010itt.2_Missense_Mutation_p.S967F|CTNND2_uc011cmy.1_Missense_Mutation_p.S721F|CTNND2_uc011cmz.1_Missense_Mutation_p.S625F|CTNND2_uc010itu.1_Non-coding_Transcript|CTNND2_uc011cmx.1_Missense_Mutation_p.S650F	NM_001332	NP_001323	Q9UQB3	CTND2_HUMAN	Homo sapiens catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) (CTNND2), mRNA.	1058					multicellular organismal development|neuron cell-cell adhesion|regulation of transcription, DNA-dependent|signal transduction|transcription, DNA-dependent	adherens junction|cytoplasm|nucleus	protein binding			NS(1)|autonomic_ganglia(1)|breast(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(29)|liver(1)|lung(71)|ovary(4)|pancreas(2)|prostate(1)|skin(5)|upper_aerodigestive_tract(4)|urinary_tract(2)	136						AGGGGAGATGGAGGGCGTGCG	0.572000														43			36		0	0	0.007835	0	0
LGSN	51557	broad.mit.edu	37	6	63990777	63990777	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr6:63990777G>A	uc003peh.3	-	3	713	c.679C>T	c.(679-681)Cct>Tct	p.P227S	LGSN_uc003pei.3_Intron	NM_016571	NP_057655	Q5TDP6	LGSN_HUMAN	Homo sapiens lengsin, lens protein with glutamine synthetase domain (LGSN), transcript variant 1, mRNA.	227					glutamine biosynthetic process		glutamate-ammonia ligase activity			NS(1)|endometrium(2)|large_intestine(5)|lung(16)|prostate(4)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	34					L-Glutamic Acid(DB00142)	GTTAAAGCAGGAAAAGATATA	0.398000														29			16		0	0	0.004007	0	0
PKDREJ	10343	broad.mit.edu	37	22	46657077	46657077	+	Missense_Mutation	SNP	A	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr22:46657077A>T	uc003bhh.3	-	0	2143	c.2143T>A	c.(2143-2145)Tcc>Acc	p.S715T		NM_006071	NP_006062	Q9NTG1	PKDRE_HUMAN	Homo sapiens polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin) (PKDREJ), mRNA.	715	REJ.				acrosome reaction|neuropeptide signaling pathway	integral to membrane	calcium ion binding|ion channel activity			NS(2)|breast(7)|central_nervous_system(1)|cervix(3)|endometrium(4)|kidney(5)|large_intestine(21)|lung(16)|ovary(2)|prostate(6)|skin(4)|upper_aerodigestive_tract(2)	73		Ovarian(80;0.00965)|all_neural(38;0.0416)		UCEC - Uterine corpus endometrioid carcinoma (28;0.00459)		TTCAAAACGGAAGCTACTATA	0.398000														53			22		0	0	0.012319	0	0
SLC35D3	340146	broad.mit.edu	37	6	137245645	137245645	+	Silent	SNP	C	G	G			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr6:137245645C>G	uc003qhe.3	+	1	1227	c.1062C>G	c.(1060-1062)ggC>ggG	p.G354G		NM_001008783	NP_001008783	Q5M8T2	S35D3_HUMAN	Homo sapiens solute carrier family 35, member D3 (SLC35D3), mRNA.	354					carbohydrate transport	integral to membrane		p.G354G(2)		central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(6)|ovary(1)	13	Colorectal(23;0.24)			GBM - Glioblastoma multiforme(68;0.000136)|OV - Ovarian serous cystadenocarcinoma(155;0.00365)		CAGCAGGTGGCCCCGCTCAGG	0.652000														16			15		0	0	0.003163	0	0
WASH1	100287171	broad.mit.edu	37	16	66940	66940	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr16:66940G>A	uc002cfg.1	-	4	1355	c.696C>T	c.(694-696)agC>agT	p.S232S		NM_182905	NP_878908	A8K0Z3	WASH1_HUMAN	Homo sapiens WAS protein family homolog 1 (WASH1), mRNA.	219					Arp2/3 complex-mediated actin nucleation|retrograde transport, endosome to Golgi	WASH complex|early endosome membrane|recycling endosome membrane	actin binding|alpha-tubulin binding	p.S232S(1)				all_lung(41;0.218)	all_cancers(5;3.04e-16)|all_epithelial(5;4.68e-12)|all_lung(10;1.94e-10)|Lung NSC(10;3.61e-10)|Acute lymphoblastic leukemia(5;0.00439)|Breast(48;0.0148)|all_hematologic(5;0.024)|Prostate(43;0.122)	Kidney(42;0.112)|KIRC - Kidney renal clear cell carcinoma(5;0.157)	all cancers(5;0.000704)|Lung(218;0.00755)|GBM - Glioblastoma multiforme(5;0.0149)|Epithelial(6;0.0154)		GCTCTCTCTTGCTGATGGACA	0.597000														39			8		0	0	0.002450	0	0
TRAPPC11	60684	broad.mit.edu	37	4	184607856	184607856	+	Silent	SNP	A	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr4:184607856A>T	uc003ivx.3	+	17	2050	c.1848A>T	c.(1846-1848)ccA>ccT	p.P616P	TRAPPC11_uc003ivw.3_Silent_p.P616P|TRAPPC11_uc010isc.3_Intron|TRAPPC11_uc003ivy.3_Silent_p.P222P	NM_021942	NP_068761	Q7Z392	CD041_HUMAN	Homo sapiens trafficking protein particle complex 11 (TRAPPC11), transcript variant 1, mRNA.	616																	CTGATTGTCCACATCCCATTA	0.368000														184			84		0	0	0.014410	0	0
GRIA4	2893	broad.mit.edu	37	11	105795269	105795269	+	Missense_Mutation	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr11:105795269G>A	uc001pix.2	+	11	2067	c.1621G>A	c.(1621-1623)Gat>Aat	p.D541N	GRIA4_uc001piw.2_Missense_Mutation_p.D541N	NM_000829	NP_000820	P48058	GRIA4_HUMAN	Homo sapiens glutamate receptor, ionotrophic, AMPA 4 (GRIA4), transcript variant 1, mRNA.	541					glutamate signaling pathway|synaptic transmission	cell junction|endocytic vesicle membrane|integral to membrane|postsynaptic membrane	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|extracellular-glutamate-gated ion channel activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(24)|liver(2)|lung(25)|ovary(4)|pancreas(1)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(6)	82		Melanoma(852;0.000902)|Acute lymphoblastic leukemia(157;0.000994)|all_hematologic(158;0.0017)|Breast(348;0.0323)		BRCA - Breast invasive adenocarcinoma(274;0.000147)|Epithelial(105;0.0291)|all cancers(92;0.0899)	L-Glutamic Acid(DB00142)	TTCCTTCTTGGATCCTCTGGC	0.423000														11			37		0	0	0.005524	0	0
PELP1	27043	broad.mit.edu	37	17	4575136	4575136	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr17:4575136G>A	uc002fyi.4	-	15	3376	c.3150C>T	c.(3148-3150)ccC>ccT	p.P1050P	PELP1_uc010vsf.2_Silent_p.P826P	NM_014389	NP_055204	Q8IZL8	PELP1_HUMAN	Homo sapiens proline, glutamate and leucine rich protein 1 (PELP1), mRNA.	1050	Glu-rich.|Pro-rich.				transcription, DNA-dependent	MLL1 complex|cytoplasm	protein binding			breast(2)|central_nervous_system(2)|endometrium(2)|large_intestine(2)|lung(3)|ovary(1)|prostate(2)|upper_aerodigestive_tract(1)	15						CAAGCTCCTGGGGAGGGGGCC	0.657000														33			15		0	0	0.004007	0	0
LRIT2	340745	broad.mit.edu	37	10	85981769	85981769	+	Silent	SNP	G	A	A			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr10:85981769G>A	uc010qmc.2	-	3	1598	c.1590C>T	c.(1588-1590)tcC>tcT	p.S530S	LRIT2_uc001kcy.3_Silent_p.S520S	NM_001017924	NP_001017924	A6NDA9	LRIT2_HUMAN	Homo sapiens leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 (LRIT2), mRNA.	520						integral to membrane				central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(13)|ovary(3)|prostate(6)|urinary_tract(1)	32						GTTCTCTAAAGGAGCCATCCT	0.597000														25			65		0	0	0.014410	0	0
GIMAP2	26157	broad.mit.edu	37	7	150389632	150389632	+	Silent	SNP	C	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr7:150389632C>T	uc003who.3	+	2	346	c.258C>T	c.(256-258)gaC>gaT	p.D86D		NM_015660	NP_056475	Q9UG22	GIMA2_HUMAN	Homo sapiens GTPase, IMAP family member 2 (GIMAP2), mRNA.	86						integral to membrane	GTP binding			kidney(1)|large_intestine(1)|lung(8)|skin(2)|urinary_tract(1)	13			OV - Ovarian serous cystadenocarcinoma(82;0.0145)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)		CTTGGAAGGAccactgtgaag	0.502000														21			20		0	0	0.007413	0	0
LOC220729	220729	broad.mit.edu	37	3	197348739	197348739	+	Splice_Site	SNP	G	C	C			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr3:197348739G>C	uc011bug.2	-	4		c.352_splice	c.e4-1		LOC220729_uc003fxy.3_Splice_Site|LOC220729_uc010iao.2_Intron					Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) pseudogene (LOC220729), non-coding RNA.																		TAATTTTCTAGCTGTGAAAGA	0.398000														73			4		0	0	0.003080	0	0
ATAD2	29028	broad.mit.edu	37	8	124384892	124384893	+	Frame_Shift_Ins	INS	-	T	T			TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr8:124384892_124384893insT	uc003yqh.4	-	2	462_463	c.354_355insA	c.(352-357)aaagaafs	p.K118fs	ATAD2_uc011lii.2_5'UTR|ATAD2_uc003yqi.4_Non-coding_Transcript|ATAD2_uc003yqj.3_Frame_Shift_Ins_p.K118fs	NM_014109	NP_054828	Q6PL18	ATAD2_HUMAN	Homo sapiens ATPase family, AAA domain containing 2 (ATAD2), mRNA.	118					regulation of transcription, DNA-dependent|transcription, DNA-dependent	mitochondrion|nucleus	ATP binding|ATPase activity	p.E119fs*8(2)		breast(3)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(12)|lung(16)|ovary(3)|prostate(3)|skin(1)|urinary_tract(2)	48	Lung NSC(37;1.25e-09)|Ovarian(258;0.00838)		STAD - Stomach adenocarcinoma(47;0.00288)			CTGTGCTCTTCTTTTTTTTTAT	0.267													---	216	---	---	7	---					
DDX12P	440081	broad.mit.edu	37	12	9573263	9573266	+	RNA	DEL	AAGG	-	-	rs67134115		TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr12:9573263_9573266delAAGG	uc021qut.1	-	10		c.2132_2135delCCTT			DDX12P_uc001qvx.4_Intron|DDX12P_uc001qvy.1_5'Flank					Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene (DDX12P), non-coding RNA.																		TCGTCCATCTaaggaaggaaggaa	0.593													---	66	---	---	7	---					
KRTAP10-6	386674	broad.mit.edu	37	21	46012219	46012220	+	In_Frame_Ins	INS	-	GGGGCGCAGCAGCTG	GGGGCGCAGCAGCTG	rs71199613		TCGA-ER-A19L-06A-12D-A197-08	TCGA-ER-A19L-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8d5ffe62-6dd9-4764-b0b7-5e3010eefe6d	338df758-f109-4331-8d51-b3ee0eab4229	g.chr21:46012219_46012220insGGGGCGCAGCAGCTG	uc002zfm.3	-	0	167_168	c.146_147insCAGCTGCTGCGCCCC	c.(145-147)ccg>ccCAGCTGCTGCGCCCCg	p.49_49P>PSCCAP	TSPEAR_uc002zfe.1_Intron|TSPEAR_uc010gpv.1_Intron	NM_198688	NP_941961	P60371	KR106_HUMAN	Homo sapiens keratin associated protein 10-6 (KRTAP10-6), mRNA.	49	29 X 5 AA repeats of C-C-X(3).					keratin filament				endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(3)|lung(6)|prostate(3)|skin(1)|stomach(1)|urinary_tract(1)	23						GGCAGGGGGCCGGGGCGCAGCA	0.688													---	51	---	---	9	---					
