Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MYH9	4627	broad.mit.edu	37	22	36710335	36710335	+	Missense_Mutation	SNP	T	T	C			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr22:36710335T>C	ENST00000216181.5	-	13	1639	c.1409A>G	c.(1408-1410)aAt>aGt	p.N470S		NM_002473.4	NP_002464.1	P35579	MYH9_HUMAN	myosin, heavy chain 9, non-muscle	470	Myosin head-like.				actin cytoskeleton reorganization|actin filament-based movement|angiogenesis|axon guidance|blood vessel endothelial cell migration|cytokinesis|integrin-mediated signaling pathway|leukocyte migration|membrane protein ectodomain proteolysis|monocyte differentiation|platelet formation|protein transport|regulation of cell shape	actomyosin contractile ring|cleavage furrow|cytosol|myosin complex|nucleus|ruffle|stress fiber|uropod	actin filament binding|actin-dependent ATPase activity|ADP binding|ATP binding|calmodulin binding|microfilament motor activity|protein anchor|protein homodimerization activity			NS(1)|breast(8)|central_nervous_system(3)|cervix(2)|endometrium(5)|kidney(4)|large_intestine(16)|lung(29)|ovary(4)|pancreas(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(6)|urinary_tract(3)	86						ATTGGTGTAATTGATGCACAG	0.527000			T	ALK	ALCL		"""Deafness, autosomal dominant 17, Epstein syndrome, Fechtner syndrome, May-Hegglin anomaly, Sebastian syndrome"""		Hereditary Macrothrombocytopenia, MYH9-associated				15	43					0	0	1	0	0
GNPTG	84572	broad.mit.edu	37	16	1412218	1412218	+	Silent	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr16:1412218G>A	ENST00000204679.4	+	7	466	c.423G>A	c.(421-423)gcG>gcA	p.A141A		NM_032520.4	NP_115909.1	Q9UJJ9	GNPTG_HUMAN	N-acetylglucosamine-1-phosphate transferase, gamma subunit	141						extracellular region|Golgi apparatus	protein binding			breast(2)|central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(2)	7		Hepatocellular(780;0.0893)				TGGAGCTGGCGTGTGGAAAAA	0.687000													7	42					0	0	1	0	0
CSAD	51380	broad.mit.edu	37	12	53553493	53553493	+	Missense_Mutation	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr12:53553493C>T	ENST00000267085.4	-	16	1536	c.1303G>A	c.(1303-1305)Gag>Aag	p.E435K	CSAD_ENST00000444623.1_Missense_Mutation_p.E408K|CSAD_ENST00000453446.2_Missense_Mutation_p.E408K|CSAD_ENST00000379843.3_Missense_Mutation_p.E261K|RP11-1136G11.8_ENST00000550908.1_lincRNA|CSAD_ENST00000379846.1_Missense_Mutation_p.E261K	NM_001244706.1|NM_015989.4	NP_001231635.1|NP_057073.4	Q9Y600	CSAD_HUMAN	cysteine sulfinic acid decarboxylase	408					carboxylic acid metabolic process		pyridoxal phosphate binding|sulfinoalanine decarboxylase activity			kidney(1)|large_intestine(2)|lung(6)|ovary(1)|prostate(4)	14					L-Cysteine(DB00151)|Pyridoxal Phosphate(DB00114)	TTGACAAACTCAGGCTGAGAG	0.562000											OREG0021859	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	4					0	0	1	0	0
FABP4	2167	broad.mit.edu	37	8	82391122	82391122	+	Missense_Mutation	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr8:82391122G>A	ENST00000256104.4	-	4	472	c.377C>T	c.(376-378)aCg>aTg	p.T126M	FABP4_ENST00000518669.1_5'UTR|RP11-157I4.4_ENST00000524085.2_RNA	NM_001442.2	NP_001433.1	P15090	FABP4_HUMAN	fatty acid binding protein 4, adipocyte	126					triglyceride catabolic process	cytoplasm|nucleus|soluble fraction	fatty acid binding|protein binding|transporter activity			breast(2)|central_nervous_system(1)|large_intestine(1)|ovary(1)|skin(1)	6			Epithelial(68;0.213)			ATAAACTCTCGTGGAAGTGAC	0.388000													39	49					0	0	1	0	0
TRPM2	7226	broad.mit.edu	37	21	45837902	45837902	+	Missense_Mutation	SNP	C	C	T	rs139485554	byFrequency	TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr21:45837902C>T	ENST00000397928.1	+	21	3684	c.3239C>T	c.(3238-3240)gCg>gTg	p.A1080V	TRPM2_ENST00000300481.9_Missense_Mutation_p.A1060V|TRPM2_ENST00000397932.2_Missense_Mutation_p.A1080V|TRPM2_ENST00000498430.1_3'UTR|TRPM2_ENST00000300482.5_Missense_Mutation_p.A1080V	NM_003307.3	NP_003298.1	O94759	TRPM2_HUMAN	transient receptor potential cation channel, subfamily M, member 2	1080						integral to plasma membrane	ADP-ribose diphosphatase activity|calcium channel activity|sodium channel activity			breast(3)|central_nervous_system(2)|endometrium(4)|kidney(3)|large_intestine(15)|lung(29)|ovary(3)|pancreas(1)|prostate(5)|skin(7)|upper_aerodigestive_tract(3)|urinary_tract(1)	76						cgccccgccgcgccgcccccc	0.627000													21	76					0	0	1	0	0
KIF21B	23046	broad.mit.edu	37	1	200965403	200965403	+	Missense_Mutation	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr1:200965403C>T	ENST00000332129.2	-	15	2514	c.2198G>A	c.(2197-2199)cGg>cAg	p.R733Q	KIF21B_ENST00000360529.5_Missense_Mutation_p.R733Q|KIF21B_ENST00000461742.2_Missense_Mutation_p.R733Q|KIF21B_ENST00000422435.2_Missense_Mutation_p.R733Q	NM_001252102.1|NM_001252103.1|NM_017596.3	NP_001239031.1|NP_001239032.1|NP_060066.2	O75037	KI21B_HUMAN	kinesin family member 21B	733					microtubule-based movement	cytoplasm|microtubule	ATP binding|microtubule motor activity			autonomic_ganglia(1)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(15)|kidney(4)|large_intestine(8)|liver(1)|lung(27)|ovary(3)|pancreas(1)|prostate(5)|skin(8)|stomach(2)|urinary_tract(2)	83						CTTAAGCAGCCGGGCGTGCTC	0.602000													30	241					0	0	1	0	0
BUB1B	701	broad.mit.edu	37	15	40501931	40501931	+	Missense_Mutation	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr15:40501931G>A	ENST00000287598.6	+	17	2434	c.2239G>A	c.(2239-2241)Gac>Aac	p.D747N	BUB1B_ENST00000412359.3_Missense_Mutation_p.D761N	NM_001211.5	NP_001202.4	O60566	BUB1B_HUMAN	BUB1 mitotic checkpoint serine/threonine kinase B	747					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|apoptosis|cell division|cell proliferation|mitotic cell cycle spindle assembly checkpoint|mitotic prometaphase|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|phosphatidylinositol-mediated signaling|protein localization to kinetochore|spindle organization	anaphase-promoting complex|condensed chromosome outer kinetochore|cytosol|microtubule organizing center|perinuclear region of cytoplasm|spindle midzone	ATP binding|protein binding|protein serine/threonine kinase activity			breast(2)|endometrium(1)|kidney(2)|large_intestine(7)|liver(2)|lung(17)|ovary(1)|stomach(2)|urinary_tract(2)	36		all_cancers(109;1.12e-18)|all_epithelial(112;1.61e-15)|Lung NSC(122;5.63e-11)|all_lung(180;1.4e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.117)		GBM - Glioblastoma multiforme(113;1.83e-06)|BRCA - Breast invasive adenocarcinoma(123;0.0556)		GTGTATAGAAGACAGACCAAT	0.423000			"""Mis, N, F, S"""			rhabdomyosarcoma			Mosaic Variegated Aneuploidy Syndrome				24	95					0	0	1	0	0
NFATC1	4772	broad.mit.edu	37	18	77171332	77171332	+	Missense_Mutation	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr18:77171332G>A	ENST00000253506.5	+	2	1426	c.1057G>A	c.(1057-1059)Gtc>Atc	p.V353I	NFATC1_ENST00000542384.1_Missense_Mutation_p.V353I|NFATC1_ENST00000329101.4_Missense_Mutation_p.V340I|NFATC1_ENST00000427363.2_Missense_Mutation_p.V353I|NFATC1_ENST00000397790.2_Intron|NFATC1_ENST00000587635.1_Missense_Mutation_p.V353I|NFATC1_ENST00000592223.1_Missense_Mutation_p.V340I|NFATC1_ENST00000591814.1_Missense_Mutation_p.V353I|NFATC1_ENST00000318065.5_Missense_Mutation_p.V340I|NFATC1_ENST00000586434.1_Missense_Mutation_p.V340I|NFATC1_ENST00000545796.1_Intron	NM_006162.3	NP_006153.2	O95644	NFAC1_HUMAN	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	353					intracellular signal transduction|positive regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter	cytoplasm|nucleus	FK506 binding|protein binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding			NS(2)|breast(1)|endometrium(7)|kidney(1)|large_intestine(4)|lung(17)|ovary(2)|prostate(4)|skin(1)|soft_tissue(1)	40		Esophageal squamous(42;0.0157)|Melanoma(33;0.144)		OV - Ovarian serous cystadenocarcinoma(15;3.73e-07)|BRCA - Breast invasive adenocarcinoma(31;0.0257)		GGTGGAGCCCGTCGGGGAGGA	0.682000													24	72					0	0	1	0	0
LPHN3	23284	broad.mit.edu	37	4	62599101	62599101	+	Missense_Mutation	SNP	A	A	G			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr4:62599101A>G	ENST00000512091.1	+	7	1771	c.1024A>G	c.(1024-1026)Att>Gtt	p.I342V	LPHN3_ENST00000504896.1_Missense_Mutation_p.I342V|LPHN3_ENST00000508693.1_Missense_Mutation_p.I410V|LPHN3_ENST00000507625.1_Missense_Mutation_p.I410V|LPHN3_ENST00000545650.1_Missense_Mutation_p.I342V|LPHN3_ENST00000514996.1_Missense_Mutation_p.I342V|LPHN3_ENST00000506720.1_Missense_Mutation_p.I410V|LPHN3_ENST00000514157.1_Missense_Mutation_p.I342V|LPHN3_ENST00000508946.1_Missense_Mutation_p.I342V|LPHN3_ENST00000506700.1_Missense_Mutation_p.I342V|LPHN3_ENST00000511324.1_Missense_Mutation_p.I410V|LPHN3_ENST00000507164.1_Missense_Mutation_p.I410V|LPHN3_ENST00000506746.1_Missense_Mutation_p.I410V|LPHN3_ENST00000514591.1_Missense_Mutation_p.I342V|LPHN3_ENST00000509896.1_Missense_Mutation_p.I410V			Q9HAR2	LPHN3_HUMAN	latrophilin 3	342	Olfactomedin-like.				neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity|sugar binding			breast(5)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(5)|kidney(4)|large_intestine(21)|lung(73)|ovary(1)|pancreas(1)|prostate(6)|upper_aerodigestive_tract(1)	125						GATTGACTACATTTACAACAC	0.408000													11	22					0	0	1	0	0
BARHL2	343472	broad.mit.edu	37	1	91182216	91182216	+	Silent	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr1:91182216G>A	ENST00000370445.4	-	1	578	c.537C>T	c.(535-537)caC>caT	p.H179H		NM_020063.1	NP_064447.1	Q9NY43	BARH2_HUMAN	BarH-like homeobox 2	179						nucleus	sequence-specific DNA binding			cervix(2)|endometrium(1)|kidney(3)|large_intestine(5)|lung(9)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	24		all_lung(203;0.0263)|Lung SC(238;0.128)		all cancers(265;0.000897)|Epithelial(280;0.00516)|OV - Ovarian serous cystadenocarcinoma(397;0.211)		TGAAGCTCTCGTGCACTGCGT	0.602000													3	15					0	0	1	0	0
SSH3	54961	broad.mit.edu	37	11	67079350	67079350	+	Missense_Mutation	SNP	G	G	A	rs78494651	by1000genomes	TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr11:67079350G>A	ENST00000308127.4	+	14	2150	c.1972G>A	c.(1972-1974)Gag>Aag	p.E658K	SSH3_ENST00000376757.5_3'UTR|SSH3_ENST00000308298.7_Missense_Mutation_p.E393K	NM_017857.3	NP_060327.3	Q8TE77	SSH3_HUMAN	slingshot protein phosphatase 3	658					regulation of actin polymerization or depolymerization|regulation of axonogenesis|regulation of lamellipodium assembly	cytoplasm|cytoskeleton|nucleus	actin binding|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity			NS(1)|breast(2)|cervix(1)|kidney(1)|large_intestine(3)|lung(6)|ovary(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	19			BRCA - Breast invasive adenocarcinoma(15;2.26e-06)			AGAGGAGGGCGAGGCCTGAGC	0.627000													15	64					0	0	1	0	0
MLLT3	4300	broad.mit.edu	37	9	20414343	20414343	+	Silent	SNP	A	A	G			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr9:20414343A>G	ENST00000380338.4	-	5	787	c.501T>C	c.(499-501)agT>agC	p.S167S	MLLT3_ENST00000355930.6_5'UTR|MLLT3_ENST00000429426.2_Silent_p.S164S|MLLT3_ENST00000475957.1_5'UTR	NM_004529.2	NP_004520.2	P42568	AF9_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	167	Poly-Ser.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	protein binding	p.S167S(19)		central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(6)|lung(24)|ovary(1)|prostate(4)|skin(1)|urinary_tract(7)	66				GBM - Glioblastoma multiforme(3;4.35e-105)|Lung(42;3.48e-06)|LUSC - Lung squamous cell carcinoma(42;7.92e-05)		tgctgctgctactgctgctgc	0.532000			T	MLL	ALL								6	73					0	0	1	0	0
SGMS1	259230	broad.mit.edu	37	10	52103821	52103821	+	Silent	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr10:52103821C>T	ENST00000361781.2	-	7	1013	c.54G>A	c.(52-54)gaG>gaA	p.E18E	SGMS1_ENST00000361543.2_Silent_p.E18E|SGMS1_ENST00000429490.1_Intron	NM_147156.3	NP_671512.1	Q86VZ5	SMS1_HUMAN	sphingomyelin synthase 1	24	SAM.				apoptosis|cell growth|sphingomyelin biosynthetic process	endoplasmic reticulum|Golgi trans cisterna|integral to Golgi membrane|nucleus|plasma membrane	ceramide cholinephosphotransferase activity|kinase activity|sphingomyelin synthase activity			endometrium(1)|kidney(1)|large_intestine(5)|liver(1)|lung(4)|ovary(1)|skin(2)|upper_aerodigestive_tract(1)	16						GCATAGCATTCTCCAGCAGCC	0.522000													18	62					0	0	1	0	0
CLIP3	25999	broad.mit.edu	37	19	36517641	36517641	+	Missense_Mutation	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr19:36517641C>T	ENST00000360535.4	-	5	636	c.409G>A	c.(409-411)Gcg>Acg	p.A137T	AC002116.7_ENST00000586962.1_RNA|CLIP3_ENST00000593074.1_Missense_Mutation_p.A137T	NM_015526.2	NP_056341.1	Q96DZ5	CLIP3_HUMAN	CAP-GLY domain containing linker protein 3	137					chaperone-mediated protein transport|fat cell differentiation|membrane biogenesis|negative regulation of microtubule polymerization|peptidyl-L-cysteine S-palmitoylation|positive regulation of apoptosis|positive regulation of endocytosis|positive regulation of establishment of protein localization in plasma membrane|positive regulation of glucose transport|positive regulation of protein phosphorylation	early endosome membrane|Golgi stack|membrane raft|microsome|plasma membrane|recycling endosome membrane|trans-Golgi network membrane	ganglioside binding|microtubule binding			cervix(1)|endometrium(6)|large_intestine(3)|lung(7)|ovary(2)|pancreas(1)|prostate(1)|skin(2)	23	Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.06)			ACGGCTGCCGCGGGGTCCCCT	0.672000													6	8					0	0	1	0	0
PGM2L1	283209	broad.mit.edu	37	11	74058232	74058232	+	Silent	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr11:74058232G>A	ENST00000298198.4	-	7	1211	c.900C>T	c.(898-900)acC>acT	p.T300T		NM_173582.3	NP_775853.2	Q6PCE3	PGM2L_HUMAN	phosphoglucomutase 2-like 1	300					glucose 1-phosphate metabolic process	cytosol	glucose-1,6-bisphosphate synthase activity|phosphoglucomutase activity			NS(2)|breast(1)|endometrium(3)|kidney(1)|large_intestine(3)|lung(11)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	26	Breast(11;3.32e-06)					GACATTTAACGGTAGAAAAGT	0.343000													10	46					0	0	1	0	0
TRAV24	28659	broad.mit.edu	37	14	22573930	22573930	+	RNA	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr14:22573930C>T	ENST00000390453.1	+	0	150																											TCCCTTCCAGCAATTTTTATG	0.463000													4	18					0	0	1	0	0
CABIN1	23523	broad.mit.edu	37	22	24509711	24509711	+	Missense_Mutation	SNP	A	A	C			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr22:24509711A>C	ENST00000398319.2	+	27	4681	c.4296A>C	c.(4294-4296)gaA>gaC	p.E1432D	CABIN1_ENST00000263119.5_Missense_Mutation_p.E1432D|CABIN1_ENST00000405822.2_Missense_Mutation_p.E1353D	NM_001199281.1	NP_001186210.1	Q9Y6J0	CABIN_HUMAN	calcineurin binding protein 1	1432					cell surface receptor linked signaling pathway|chromatin modification	nucleus	protein phosphatase inhibitor activity			breast(2)|central_nervous_system(2)|endometrium(6)|kidney(6)|large_intestine(13)|liver(1)|lung(18)|ovary(5)|pancreas(3)|prostate(1)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	65						CCACAGAAGAAAGAGGTATGA	0.542000													16	49					0	0	1	0	0
SSTR5	6755	broad.mit.edu	37	16	1129503	1129503	+	Missense_Mutation	SNP	C	C	T	rs142537827		TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr16:1129503C>T	ENST00000293897.4	+	1	723	c.635C>T	c.(634-636)gCg>gTg	p.A212V	SSTR5_ENST00000397547.2_Missense_Mutation_p.A212V|SSTR5_ENST00000562758.1_Missense_Mutation_p.A212V	NM_001053.3	NP_001044.1	P35346	SSR5_HUMAN	somatostatin receptor 5	212					negative regulation of cell proliferation	integral to plasma membrane	somatostatin receptor activity			endometrium(2)|lung(5)|prostate(1)|skin(1)	9		Hepatocellular(780;0.00369)			Octreotide(DB00104)	GGCTTCTTCGCGCCGCTGCTG	0.706000													3	41					0	0	1	0	0
IQGAP1	8826	broad.mit.edu	37	15	90984759	90984759	+	Missense_Mutation	SNP	T	T	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr15:90984759T>A	ENST00000268182.5	+	8	795	c.671T>A	c.(670-672)aTt>aAt	p.I224N	IQGAP1_ENST00000560738.1_Intron	NM_003870.3	NP_003861.1	P46940	IQGA1_HUMAN	IQ motif containing GTPase activating protein 1	224					energy reserve metabolic process|regulation of insulin secretion|small GTPase mediated signal transduction	actin filament|cytoplasm|midbody|nucleus|plasma membrane	calmodulin binding|GTPase inhibitor activity|protein phosphatase binding|Ras GTPase activator activity			breast(2)|central_nervous_system(3)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(14)|liver(1)|lung(18)|ovary(2)|pancreas(1)|prostate(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	59	Melanoma(11;0.00551)|Lung NSC(78;0.0237)|all_lung(78;0.0488)		BRCA - Breast invasive adenocarcinoma(143;0.0745)|KIRC - Kidney renal clear cell carcinoma(17;0.138)|Kidney(142;0.194)			GTTATTGCTATTAATGAAGCT	0.353000													13	34					0	0	1	0	0
CROT	54677	broad.mit.edu	37	7	86978395	86978395	+	Missense_Mutation	SNP	A	A	G			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr7:86978395A>G	ENST00000331536.3	+	3	196	c.11A>G	c.(10-12)cAa>cGa	p.Q4R	CROT_ENST00000442291.1_Missense_Mutation_p.Q4R|CROT_ENST00000412227.2_Missense_Mutation_p.Q4R|CROT_ENST00000419147.2_Missense_Mutation_p.Q4R	NM_021151.3	NP_066974.2	Q9UKG9	OCTC_HUMAN	carnitine O-octanoyltransferase	4					fatty acid beta-oxidation using acyl-CoA oxidase|generation of precursor metabolites and energy|transport	peroxisomal matrix	carnitine O-octanoyltransferase activity			NS(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(21)|ovary(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	37	Esophageal squamous(14;0.0058)|all_lung(186;0.201)|Lung NSC(181;0.203)				L-Carnitine(DB00583)	ATGGAAAATCAATTGGCTAAA	0.353000													7	33					0	0	1	0	0
PBX2	5089	broad.mit.edu	37	6	32155509	32155509	+	Missense_Mutation	SNP	T	T	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr6:32155509T>A	ENST00000375050.4	-	5	1055	c.785A>T	c.(784-786)tAt>tTt	p.Y262F		NM_002586.4	NP_002577.2	P40425	PBX2_HUMAN	pre-B-cell leukemia homeobox 2	262							transcription factor binding	p.Y262F(3)		endometrium(1)|kidney(1)|lung(9)|ovary(1)|prostate(2)	14						GGAGTAGAAATACTCATTTAG	0.517000													3	31					0	0	1	0	0
GABBR1	2550	broad.mit.edu	37	6	29599320	29599320	+	Missense_Mutation	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr6:29599320G>A	ENST00000377034.4	-	3	477	c.142C>T	c.(142-144)Cgg>Tgg	p.R48W	GABBR1_ENST00000376977.3_Missense_Mutation_p.R48W|GABBR1_ENST00000377016.4_Missense_Mutation_p.R48W	NM_001470.2	NP_001461.1	Q9UBS5	GABR1_HUMAN	gamma-aminobutyric acid (GABA) B receptor, 1	48	Sushi 1.				gamma-aminobutyric acid signaling pathway|negative regulation of adenylate cyclase activity|synaptic transmission	cell junction|extracellular region|integral to plasma membrane|postsynaptic membrane	G-protein coupled receptor activity|GABA-B receptor activity			endometrium(3)|kidney(1)|large_intestine(13)|liver(1)|lung(16)|ovary(5)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	47					Baclofen(DB00181)|Progabide(DB00837)	ACCTGGTCCCGAGTCAGGCCC	0.612000													33	167					0	0	1	0	0
DNM1P47	100216544	broad.mit.edu	37	15	102292785	102292785	+	RNA	SNP	C	C	G	rs61084368		TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr15:102292785C>G	ENST00000561463.1	+	0	831																		p.Q125E(1)									TGCTGCTTCTCAGAGCTGCTG	0.602000													5	57					0	0	1	0	0
CYP2A7	1549	broad.mit.edu	37	19	41382568	41382568	+	Silent	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr19:41382568G>A	ENST00000301146.4	-	8	1708	c.1167C>T	c.(1165-1167)acC>acT	p.T389T	CTC-490E21.12_ENST00000601627.1_Intron|CYP2A7_ENST00000291764.3_Silent_p.T338T	NM_000764.2	NP_000755.2	P20853	CP2A7_HUMAN	cytochrome P450, family 2, subfamily A, polypeptide 7	389						endoplasmic reticulum membrane|microsome	aromatase activity|electron carrier activity|heme binding|oxygen binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(6)|lung(7)|ovary(4)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	27			LUSC - Lung squamous cell carcinoma(20;0.000219)|Lung(22;0.000959)			GGAACACTTCGGTGCCCTGGT	0.577000													21	62					0	0	1	0	0
TGIF2LX	90316	broad.mit.edu	37	X	89177312	89177312	+	Silent	SNP	C	C	G			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chrX:89177312C>G	ENST00000561129.2	+	1	358	c.228C>G	c.(226-228)gcC>gcG	p.A76A	TGIF2LX_ENST00000283891.5_Silent_p.A76A			Q8IUE1	TF2LX_HUMAN	TGFB-induced factor homeobox 2-like, X-linked	76						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(29)|ovary(1)|skin(3)|urinary_tract(1)	40						GGTTTAAGGCCTACCCTTCAG	0.468000													39	51					0	0	1	0	0
FBN2	2201	broad.mit.edu	37	5	127744375	127744375	+	Missense_Mutation	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr5:127744375C>T	ENST00000508053.1	-	14	2044	c.1070G>A	c.(1069-1071)cGa>cAa	p.R357Q	FBN2_ENST00000262464.4_Missense_Mutation_p.R357Q|FBN2_ENST00000508989.1_Missense_Mutation_p.R324Q			P35556	FBN2_HUMAN	fibrillin 2	357	EGF-like 5; calcium-binding.				bone trabecula formation|negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta|positive regulation of bone mineralization|positive regulation of osteoblast differentiation	microfibril	calcium ion binding|extracellular matrix structural constituent			NS(1)|autonomic_ganglia(1)|biliary_tract(1)|breast(1)|endometrium(15)|haematopoietic_and_lymphoid_tissue(4)|kidney(13)|large_intestine(37)|liver(1)|lung(89)|ovary(9)|pancreas(2)|prostate(6)|skin(10)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(1)	197		all_cancers(142;0.0216)|Prostate(80;0.0551)	KIRC - Kidney renal clear cell carcinoma(527;0.0268)|Kidney(363;0.0488)	OV - Ovarian serous cystadenocarcinoma(64;0.0821)|Epithelial(69;0.146)		ACCGATGCATCGAGAGCCATC	0.418000													15	61					0	0	1	0	0
SLC27A1	376497	broad.mit.edu	37	19	17599705	17599705	+	Silent	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr19:17599705G>A	ENST00000252595.7	+	5	940	c.843G>A	c.(841-843)gcG>gcA	p.A281A	SLC27A1_ENST00000598424.1_Silent_p.A102A|SLC27A1_ENST00000442725.1_Silent_p.A281A	NM_198580.1	NP_940982.1	Q6PCB7	S27A1_HUMAN	solute carrier family 27 (fatty acid transporter), member 1	281	Sufficient for oligomerization (By similarity).				cardiolipin biosynthetic process|fatty acid metabolic process|long-chain fatty acid transport|negative regulation of phospholipid biosynthetic process|phosphatidic acid biosynthetic process|phosphatidylcholine biosynthetic process|phosphatidylethanolamine biosynthetic process|phosphatidylinositol biosynthetic process|phosphatidylserine biosynthetic process|transmembrane transport	endomembrane system|integral to membrane	fatty acid transporter activity|nucleotide binding			breast(1)|endometrium(4)|kidney(2)|large_intestine(4)|lung(9)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	23						GCATGCAGGCGGCTGACGTGC	0.677000													13	27					0	0	1	0	0
TOP2B	7155	broad.mit.edu	37	3	25668285	25668285	+	Missense_Mutation	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr3:25668285C>T	ENST00000435706.2	-	17	2273	c.2072G>A	c.(2071-2073)cGt>cAt	p.R691H	TOP2B_ENST00000264331.4_Missense_Mutation_p.R696H			Q02880	TOP2B_HUMAN	topoisomerase (DNA) II beta 180kDa	696					DNA topological change|DNA-dependent DNA replication|mitotic cell cycle G2/M transition decatenation checkpoint|mitotic recombination|resolution of meiotic recombination intermediates|sister chromatid segregation	cytosol|DNA topoisomerase complex (ATP-hydrolyzing)|nucleolus|nucleoplasm|synaptonemal complex|WINAC complex	ATP binding|chromatin binding|DNA topoisomerase (ATP-hydrolyzing) activity|DNA-dependent ATPase activity|histone deacetylase binding|protein C-terminus binding|protein heterodimerization activity|protein kinase C binding|sequence-specific DNA binding transcription factor activity			breast(2)|endometrium(5)|kidney(1)|large_intestine(10)|lung(14)|ovary(1)|skin(2)|stomach(1)	36						ATGTAGCCTACGCTGTCTCCG	0.393000													3	14					0	0	1	0	0
NUP214	8021	broad.mit.edu	37	9	134021562	134021562	+	Missense_Mutation	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr9:134021562G>A	ENST00000359428.5	+	13	1960	c.1816G>A	c.(1816-1818)Gca>Aca	p.A606T	RP11-544A12.4_ENST00000589667.1_RNA|RP11-544A12.4_ENST00000415391.2_RNA|RP11-544A12.4_ENST00000587408.1_RNA|RP11-544A12.4_ENST00000586290.1_RNA|NUP214_ENST00000451030.1_Missense_Mutation_p.A606T|RP11-544A12.4_ENST00000588378.1_RNA|RP11-544A12.4_ENST00000589540.1_RNA|RP11-544A12.4_ENST00000590461.1_RNA|RP11-544A12.4_ENST00000587264.1_RNA|NUP214_ENST00000411637.2_Missense_Mutation_p.A595T			P35658	NU214_HUMAN	nucleoporin 214kDa	606	11 X 5 AA approximate repeats.				carbohydrate metabolic process|glucose transport|mRNA metabolic process|protein export from nucleus|regulation of glucose transport|transmembrane transport|viral reproduction	cytosol|nuclear pore|nucleoplasm	protein binding			NS(1)|breast(9)|central_nervous_system(3)|endometrium(13)|kidney(2)|large_intestine(9)|liver(2)|lung(29)|ovary(2)|prostate(3)|skin(7)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	86	all_hematologic(7;0.0028)	Myeloproliferative disorder(178;0.204)		OV - Ovarian serous cystadenocarcinoma(145;3.42e-05)|Epithelial(140;0.000256)		CTCCCAGAGCGCACCCCCGAT	0.547000			T	"""DEK, SET, ABL1"""	"""AML, T-ALL"""								6	421					0	0	1	0	0
PNMAL1	55228	broad.mit.edu	37	19	46973295	46973295	+	Missense_Mutation	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr19:46973295G>A	ENST00000313683.10	-	2	1303	c.998C>T	c.(997-999)tCt>tTt	p.S333F	PNMAL1_ENST00000602246.1_Intron|PNMAL1_ENST00000438932.2_Missense_Mutation_p.S333F	NM_001103149.1|NM_018215.3	NP_001096619.1|NP_060685.2	Q86V59	PNML1_HUMAN	paraneoplastic Ma antigen family-like 1	333										cervix(1)|endometrium(2)|large_intestine(8)|lung(8)|prostate(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	25		Ovarian(192;0.00965)|all_neural(266;0.0459)		OV - Ovarian serous cystadenocarcinoma(262;0.000166)|all cancers(93;0.0014)|GBM - Glioblastoma multiforme(486;0.0421)|Epithelial(262;0.0427)		GTCTGACTCAGAGGCGCCTCC	0.597000													85	174					0	0	1	0	0
PRB2	653247	broad.mit.edu	37	12	11546491	11546491	+	Missense_Mutation	SNP	C	C	T			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr12:11546491C>T	ENST00000389362.4	-	3	556	c.521G>A	c.(520-522)cGa>cAa	p.R174Q	PRB1_ENST00000546254.1_Intron	NM_006248.3	NP_006239.3			proline-rich protein BstNI subfamily 2									p.R153L(1)|p.R174L(1)		NS(1)|breast(1)|endometrium(2)|kidney(3)|large_intestine(3)|lung(14)|pancreas(1)|prostate(5)|skin(4)|stomach(2)|urinary_tract(1)	37		all_cancers(2;0.00558)|Acute lymphoblastic leukemia(2;3.94e-11)|all_hematologic(2;3.6e-09)	OV - Ovarian serous cystadenocarcinoma(49;0.185)			TGGAGGAGATCGAGAACTTCG	0.607000													8	689					0	0	1	0	0
MLLT3	4300	broad.mit.edu	37	9	20414340	20414340	+	Silent	SNP	G	G	A			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr9:20414340G>A	ENST00000380338.4	-	5	790	c.504C>T	c.(502-504)agC>agT	p.S168S	MLLT3_ENST00000355930.6_5'UTR|MLLT3_ENST00000429426.2_Silent_p.S165S|MLLT3_ENST00000475957.1_5'UTR	NM_004529.2	NP_004520.2	P42568	AF9_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	168	Poly-Ser.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	protein binding	p.S168S(5)		central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(6)|lung(24)|ovary(1)|prostate(4)|skin(1)|urinary_tract(7)	66				GBM - Glioblastoma multiforme(3;4.35e-105)|Lung(42;3.48e-06)|LUSC - Lung squamous cell carcinoma(42;7.92e-05)		tgctgctgctgctactgctgc	0.537000			T	MLL	ALL								7	74					0	0	1	0	0
ADRA2B	151	broad.mit.edu	37	2	96780975	96780977	+	In_Frame_Del	DEL	TCC	TCC	-	rs71989981		TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr2:96780975_96780977delTCC	ENST00000409345.3	-	1	1007_1009	c.912_914delGGA	c.(910-915)gaa>ga	p.EE304del		NM_000682.5	NP_000673.2	P18089	ADA2B_HUMAN	adrenoceptor alpha 2B	307	Asp/Glu-rich (acidic).				activation of MAPK activity by adrenergic receptor signaling pathway|activation of protein kinase B activity|blood coagulation|cell-cell signaling|epidermal growth factor receptor transactivation by G-protein coupled receptor signaling pathway|negative regulation of epinephrine secretion|negative regulation of norepinephrine secretion|positive regulation of neuron differentiation	integral to plasma membrane	alpha2-adrenergic receptor activity|epinephrine binding|protein binding			endometrium(2)|large_intestine(2)|lung(9)|ovary(3)	16					Bethanidine(DB00217)|Brimonidine(DB00484)|Debrisoquin(DB04840)|Ergotamine(DB00696)|Fenoldopam(DB00800)|Guanadrel Sulfate(DB00226)|Guanethidine(DB01170)|Lofexidine(DB04948)|Norepinephrine(DB00368)|Yohimbine(DB01392)	TTCACActcttcctcctcctcct	0.655													2	4	---	---	---	---					
RPLP0P2	113157	broad.mit.edu	37	11	61405227	61405236	+	RNA	DEL	AGAAAGAAAG	AGAAAGAAAG	-			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr11:61405227_61405236delAGAAAGAAAG	ENST00000496593.1	+	0	1831_1840					NR_002775.2																						aaacaaagaaagaaagaaagagaaagaaag	0.352													2	4	---	---	---	---					
RPL6	6128	broad.mit.edu	37	12	112844148	112844149	+	Splice_Site	DEL	TG	TG	-			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr12:112844148_112844149delTG	ENST00000424576.2	-	5	666		c.e5-2		RPL6_ENST00000202773.9_Splice_Site	NM_001024662.1	NP_001019833.1	Q02878	RL6_HUMAN	ribosomal protein L6						endocrine pancreas development|regulation of transcription, DNA-dependent|translational elongation|translational termination|viral transcription	cytosolic large ribosomal subunit	DNA binding|RNA binding|structural constituent of ribosome			cervix(1)|large_intestine(6)|lung(3)	10						AACCACCCTCTGTAAGTTAAAA	0.327													9	46	---	---	---	---					
HERC2P9	440248	broad.mit.edu	37	15	28900331	28900331	+	RNA	DEL	A	A	-			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr15:28900331delA	ENST00000528584.1	+	0	14					NR_036443.1																						actctgtctcaaaaaaaaaaa	0.413													4	6	---	---	---	---					
CSPG4P5	114817	broad.mit.edu	37	15	84954439	84954439	+	RNA	DEL	G	G	-			TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr15:84954439delG	ENST00000558801.1	-	0	7383																											CTGCCCTACTGGGACTGTGTG	0.547													2	4	---	---	---	---					
ZNF761	388561	broad.mit.edu	37	19	53946133	53946133	+	RNA	DEL	A	A	-	rs35108555		TCGA-BB-7861-01A-11D-2229-08	TCGA-BB-7861-10A-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	77cb5c69-f15e-45de-a060-0e8b52648209	baa74281-5ff2-4100-a721-5698c8e648b5	g.chr19:53946133delA	ENST00000454407.1	+	0	55				TPM3P9_ENST00000424846.3_RNA			Q86XN6	ZN761_HUMAN	zinc finger protein 761						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(1)|kidney(2)|large_intestine(5)|lung(13)|ovary(1)|prostate(2)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	30				GBM - Glioblastoma multiforme(134;0.00786)		TCATGTTGTGAAAAAAAAAAT	0.348													5	3	---	---	---	---					
