Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
AHDC1	27245	broad.mit.edu	37	1	27878461	27878461	+	Missense_Mutation	SNP	C	C	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr1:27878461C>T	ENST00000374011.2	-	6	1134	c.166G>A	c.(166-168)Gcc>Acc	p.A56T	AHDC1_ENST00000482400.2_Intron|AHDC1_ENST00000247087.5_Missense_Mutation_p.A56T	NM_001029882.2	NP_001025053.1	Q5TGY3	AHDC1_HUMAN	AT hook, DNA binding motif, containing 1	56	Pro-rich.						DNA binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(3)|large_intestine(8)|lung(20)|prostate(1)|skin(3)|upper_aerodigestive_tract(2)	42		all_lung(284;1.06e-05)|Lung NSC(340;1.86e-05)|Colorectal(325;3.46e-05)|Renal(390;0.0007)|Breast(348;0.0021)|Ovarian(437;0.00503)|Myeloproliferative disorder(586;0.0255)|all_neural(195;0.0381)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0434)|OV - Ovarian serous cystadenocarcinoma(117;8.48e-25)|Colorectal(126;9.17e-09)|COAD - Colon adenocarcinoma(152;1.84e-06)|KIRC - Kidney renal clear cell carcinoma(1967;0.00192)|BRCA - Breast invasive adenocarcinoma(304;0.00259)|STAD - Stomach adenocarcinoma(196;0.00311)|READ - Rectum adenocarcinoma(331;0.0291)		TCGGAGAAGGCGTGGGTGGAG	0.756000													9	21					0	0	0.335167	0	0
CSK	1445	broad.mit.edu	37	15	75091169	75091169	+	Missense_Mutation	SNP	C	C	A			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr15:75091169C>A	ENST00000220003.9	+	4	861	c.132C>A	c.(130-132)gaC>gaA	p.D44E	CSK_ENST00000309470.9_Missense_Mutation_p.D44E|CSK_ENST00000439220.2_Missense_Mutation_p.D44E|CSK_ENST00000567571.1_Missense_Mutation_p.D44E	NM_004383.2	NP_004374.1	P41240	CSK_HUMAN	c-src tyrosine kinase	44	Interaction with PTPN8 (By similarity).|SH3.				blood coagulation|epidermal growth factor receptor signaling pathway|T cell costimulation|T cell receptor signaling pathway	centrosome|cytosol|Golgi apparatus	ATP binding|non-membrane spanning protein tyrosine kinase activity|protein C-terminus binding			central_nervous_system(1)|lung(2)	3						CTCCCCAGGACCCCAACTGGT	0.627000													8	61					3.86212e-05	4.72037e-05	0.361761	1	0
TTN	7273	broad.mit.edu	37	2	179458701	179458701	+	Missense_Mutation	SNP	T	T	G			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr2:179458701T>G	ENST00000589042.1	-	297	58643	c.58419A>C	c.(58417-58419)caA>caC	p.Q19473H	TTN_ENST00000460472.2_Missense_Mutation_p.Q10408H|TTN-AS1_ENST00000592750.1_RNA|TTN-AS1_ENST00000592630.1_RNA|TTN-AS1_ENST00000592689.1_RNA|TTN-AS1_ENST00000591332.1_RNA|TTN-AS1_ENST00000590932.1_RNA|TTN_ENST00000591111.1_Missense_Mutation_p.Q17832H|TTN-AS1_ENST00000419746.1_RNA|TTN_ENST00000342992.6_Missense_Mutation_p.Q16905H|TTN_ENST00000342175.6_Missense_Mutation_p.Q10600H|TTN-AS1_ENST00000586452.1_RNA|TTN-AS1_ENST00000585451.1_RNA|TTN-AS1_ENST00000589907.1_RNA|TTN-AS1_ENST00000589234.1_RNA|TTN-AS1_ENST00000590807.1_RNA|TTN_ENST00000359218.5_Missense_Mutation_p.Q10533H|TTN-AS1_ENST00000456053.1_RNA	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	17832	Fibronectin type-III 41.						ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			CAACATTAACTTGACAGAAAC	0.368000													81	213					0	0	0.870114	0	0
TXNDC11	51061	broad.mit.edu	37	16	11829975	11829975	+	Silent	SNP	C	C	A			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr16:11829975C>A	ENST00000356957.3	-	2	476	c.369G>T	c.(367-369)cgG>cgT	p.R123R	TXNDC11_ENST00000283033.5_Silent_p.R123R			Q6PKC3	TXD11_HUMAN	thioredoxin domain containing 11	123	Thioredoxin 1.				cell redox homeostasis	endoplasmic reticulum membrane|integral to membrane				endometrium(3)|large_intestine(5)|lung(7)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	21						CCTCTGAATCCCGTCGAACGT	0.522000													31	92					5.90632e-09	7.49649e-09	0.760397	1	0
TSSC2	650368	broad.mit.edu	37	11	3427845	3427845	+	RNA	SNP	C	C	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr11:3427845C>T	ENST00000529482.1	+	0	962																											CTTCAAGTGGCAGGAGCAGAA	0.587000													5	53					0	0	0.184627	0	0
CATSPERB	79820	broad.mit.edu	37	14	92126293	92126293	+	Missense_Mutation	SNP	A	A	C			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr14:92126293A>C	ENST00000256343.3	-	15	1476	c.1320T>G	c.(1318-1320)ttT>ttG	p.F440L		NM_024764.2	NP_079040.2	Q9H7T0	CTSRB_HUMAN	catsper channel auxiliary subunit beta	440					cell differentiation|multicellular organismal development|spermatogenesis	integral to membrane				NS(1)|breast(4)|central_nervous_system(1)|kidney(3)|large_intestine(15)|liver(1)|lung(12)|ovary(2)|pancreas(1)|prostate(3)|skin(9)|urinary_tract(2)	54		all_cancers(154;0.0663)|all_epithelial(191;0.236)				CTATTAATTGAAAGGTGTTGC	0.353000													68	175					0	0	0.870114	0	0
CHD2	1106	broad.mit.edu	37	15	93524619	93524619	+	Missense_Mutation	SNP	C	C	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr15:93524619C>T	ENST00000394196.4	+	24	4066	c.2998C>T	c.(2998-3000)Cgg>Tgg	p.R1000W	CHD2_ENST00000557381.1_Missense_Mutation_p.R1000W	NM_001271.3	NP_001262.3	O14647	CHD2_HUMAN	chromodomain helicase DNA binding protein 2	1000	Glu-rich.				regulation of transcription from RNA polymerase II promoter	nucleus	ATP binding|ATP-dependent DNA helicase activity|DNA binding			breast(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(5)|kidney(2)|large_intestine(10)|lung(17)|ovary(1)|prostate(2)|skin(2)|stomach(1)|urinary_tract(2)	47	Lung NSC(78;0.00976)|all_lung(78;0.016)		BRCA - Breast invasive adenocarcinoma(143;0.0282)|OV - Ovarian serous cystadenocarcinoma(32;0.0814)			TGAAATTTTGCGGTTGGCTGA	0.383000													4	102					0	0	0.184627	0	0
HEATR5B	54497	broad.mit.edu	37	2	37227889	37227889	+	Silent	SNP	C	C	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr2:37227889C>T	ENST00000233099.5	-	33	5480	c.5385G>A	c.(5383-5385)aaG>aaA	p.K1795K	HEATR5B_ENST00000354531.2_Silent_p.K1706K	NM_019024.1	NP_061897.1	Q9P2D3	HTR5B_HUMAN	HEAT repeat containing 5B	1795							binding			breast(3)|cervix(3)|endometrium(3)|kidney(3)|large_intestine(11)|lung(31)|ovary(5)|pancreas(1)|prostate(1)|skin(10)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	77		all_hematologic(82;0.21)				TATCTGCAGACTTTATTGCTG	0.398000													52	128					0	0	0.870114	0	0
ECHDC2	55268	broad.mit.edu	37	1	53373542	53373542	+	Missense_Mutation	SNP	A	A	G			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr1:53373542A>G	ENST00000536120.1	-	7	1041	c.224T>C	c.(223-225)aTc>aCc	p.I75T	ECHDC2_ENST00000371522.4_Missense_Mutation_p.I121T|ECHDC2_ENST00000358358.5_Missense_Mutation_p.I121T|ECHDC2_ENST00000541281.1_Missense_Mutation_p.I75T			Q86YB7	ECHD2_HUMAN	enoyl CoA hydratase domain containing 2	121					fatty acid metabolic process	mitochondrion	lyase activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(3)|prostate(1)|urinary_tract(1)	12						ATCCTCACCGATGTCATTCAT	0.607000													4	57					0	0	0.184627	0	0
STRN4	29888	broad.mit.edu	37	19	47234130	47234130	+	Splice_Site	SNP	C	C	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr19:47234130C>T	ENST00000391910.3	-	6	1188	c.737_splice	c.e6-1	p.R246_splice	STRN4_ENST00000263280.6_Splice_Site_p.R246_splice|CTB-174O21.2_ENST00000600716.1_RNA|STRN4_ENST00000539396.1_Splice_Site_p.R127_splice			Q9NRL3	STRN4_HUMAN	striatin, calmodulin binding protein 4	246						cytoplasm|membrane	armadillo repeat domain binding|calmodulin binding|protein complex binding|protein phosphatase 2A binding			NS(1)|endometrium(3)|kidney(2)|large_intestine(4)|lung(4)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	17		Ovarian(192;0.0129)|all_neural(266;0.0459)|Breast(70;0.212)		OV - Ovarian serous cystadenocarcinoma(262;0.000563)|all cancers(93;0.00138)|Epithelial(262;0.0217)|GBM - Glioblastoma multiforme(486;0.035)		CTGCCGCGTTCCTGCCAAAGA	0.622000													11	116					0	0	0.387290	0	0
KAT6A	7994	broad.mit.edu	37	8	41801275	41801275	+	Missense_Mutation	SNP	C	C	A			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr8:41801275C>A	ENST00000396930.3	-	14	2762	c.2219G>T	c.(2218-2220)cGt>cTt	p.R740L	KAT6A_ENST00000406337.1_Missense_Mutation_p.R740L|KAT6A_ENST00000265713.2_Missense_Mutation_p.R740L|KAT6A_ENST00000485568.1_Missense_Mutation_p.R740L	NM_001099412.1	NP_001092882.1	Q92794	MYST3_HUMAN	K(lysine) acetyltransferase 6A	740	Catalytic.|Mediates interaction with BRPF1, required for histone H3 acetyltransferase activity.				histone H3 acetylation|myeloid cell differentiation|negative regulation of transcription, DNA-dependent|nucleosome assembly|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	MOZ/MORF histone acetyltransferase complex|nucleosome	DNA binding|histone acetyltransferase activity|transcription coactivator activity|transcription factor binding|zinc ion binding										CTGGTCACTACGGAAGTCCAG	0.403000													29	74					1.80694e-10	2.38517e-10	0.740014	1	0
OR1E1	8387	broad.mit.edu	37	17	3301331	3301331	+	Missense_Mutation	SNP	G	G	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr17:3301331G>T	ENST00000322608.2	-	1	373	c.374C>A	c.(373-375)gCc>gAc	p.A125D		NM_003553.2	NP_003544.2	P30953	OR1E1_HUMAN	olfactory receptor, family 1, subfamily E, member 1	125					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(3)|large_intestine(2)|lung(5)	10						GAAGCAGATGGCCACATAGCG	0.572000													4	100					0.150653	0.160373	0.150653	1	0
ASAH2	56624	broad.mit.edu	37	10	51974612	51974612	+	Missense_Mutation	SNP	G	G	C			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr10:51974612G>C	ENST00000395526.3	-	8	1030	c.1031C>G	c.(1030-1032)gCc>gGc	p.A344G	ASAH2_ENST00000443575.1_Missense_Mutation_p.A186G|ASAH2_ENST00000447815.1_Missense_Mutation_p.A344G|ASAH2_ENST00000329428.6_Missense_Mutation_p.A325G	NM_019893.2	NP_063946.2	Q9NR71	ASAH2_HUMAN	N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2	344					apoptosis|ceramide metabolic process|signal transduction	integral to membrane|mitochondrion|plasma membrane	ceramidase activity			large_intestine(1)|lung(9)|urinary_tract(1)	11						TGAAGCAAAGGCTGCTACAAA	0.433000													43	76					0	0	0.864702	0	0
GNA12	2768	broad.mit.edu	37	7	2770999	2770999	+	Missense_Mutation	SNP	G	G	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr7:2770999G>T	ENST00000275364.3	-	4	1124	c.962C>A	c.(961-963)cCg>cAg	p.P321Q	GNA12_ENST00000407653.1_Missense_Mutation_p.P245Q|GNA12_ENST00000407904.3_Missense_Mutation_p.P262Q|GNA12_ENST00000396960.3_Missense_Mutation_p.P173Q|GNA12_ENST00000491117.1_5'UTR|AMZ1_ENST00000489665.1_Intron|GNA12_ENST00000544127.1_Missense_Mutation_p.P228Q	NM_007353.2	NP_031379.2	Q03113	GNA12_HUMAN	guanine nucleotide binding protein (G protein) alpha 12	321					G-protein signaling, coupled to cAMP nucleotide second messenger|platelet activation|Rho protein signal transduction	brush border membrane|heterotrimeric G-protein complex	D5 dopamine receptor binding|G-protein beta/gamma-subunit complex binding|GTP binding|GTPase activity|signal transducer activity			endometrium(1)|large_intestine(5)|lung(3)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	13		Ovarian(82;0.0112)		OV - Ovarian serous cystadenocarcinoma(56;1.02e-13)		CAGCCTGTGCGGGTCGCCCCT	0.582000													3	75					0.00909568	0.0100052	0.150653	1	0
MST1L	11223	broad.mit.edu	37	1	17085189	17085189	+	RNA	SNP	A	A	G			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr1:17085189A>G	ENST00000455405.2	-	0	87																		p.S428P(1)									TCCAGGATTGATGGCGGCTGG	0.572000													3	70					0	0	0.150653	0	0
FAM217B	63939	broad.mit.edu	37	20	58520018	58520018	+	Missense_Mutation	SNP	G	G	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr20:58520018G>T	ENST00000358293.3	+	5	1435	c.1020G>T	c.(1018-1020)aaG>aaT	p.K340N	FAM217B_ENST00000360816.3_Missense_Mutation_p.K340N|FAM217B_ENST00000469084.1_3'UTR	NM_001190826.1	NP_001177755.1	Q9NTX9	CT177_HUMAN	family with sequence similarity 217, member B	340																	ATTCCTGTAAGGCCTCCAAAA	0.493000													4	87					0.000602214	0.000685278	0.184627	1	0
CCDC114	93233	broad.mit.edu	37	19	48807247	48807247	+	Silent	SNP	C	C	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr19:48807247C>T	ENST00000315396.7	-	7	1387	c.705G>A	c.(703-705)caG>caA	p.Q235Q		NM_144577.3	NP_653178.3	Q96M63	CC114_HUMAN	coiled-coil domain containing 114	235										cervix(2)|endometrium(3)|kidney(1)|large_intestine(5)|lung(5)|ovary(1)|pancreas(1)|prostate(3)|skin(2)|stomach(1)	24		all_epithelial(76;9.64e-05)|all_lung(116;0.000147)|Lung NSC(112;0.000251)|Prostate(7;0.0187)|all_neural(266;0.0228)|Ovarian(192;0.113)		OV - Ovarian serous cystadenocarcinoma(262;0.000134)|all cancers(93;0.000162)|Epithelial(262;0.0134)|GBM - Glioblastoma multiforme(486;0.0143)		CGGGATCCGGCTGCCGGTCGT	0.642000													58	105					0	0	0.870114	0	0
AGPAT9	84803	broad.mit.edu	37	4	84502830	84502830	+	Silent	SNP	A	A	G			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr4:84502830A>G	ENST00000395226.2	+	4	542	c.324A>G	c.(322-324)gtA>gtG	p.V108V	AGPAT9_ENST00000264409.4_Silent_p.V108V	NM_001256421.1	NP_001243350.1	Q53EU6	GPAT3_HUMAN	1-acylglycerol-3-phosphate O-acyltransferase 9	108					phospholipid biosynthetic process|regulation of TOR signaling cascade|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane	glycerol-3-phosphate O-acyltransferase activity			endometrium(1)|kidney(1)|large_intestine(4)|lung(4)|skin(3)	13		Hepatocellular(203;0.114)				AAGCCATTGTAGAAGATGAAG	0.463000													89	196					0	0	0.870114	0	0
TACR3	6870	broad.mit.edu	37	4	104512715	104512715	+	Silent	SNP	G	G	A			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr4:104512715G>A	ENST00000304883.2	-	4	1154	c.1014C>T	c.(1012-1014)taC>taT	p.Y338Y	RP11-297P16.3_ENST00000502936.1_RNA|RP11-297P16.3_ENST00000512401.1_RNA	NM_001059.2	NP_001050.1	P29371	NK3R_HUMAN	tachykinin receptor 3	338						integral to plasma membrane	tachykinin receptor activity			breast(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(9)|lung(19)|ovary(3)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	51		Hepatocellular(203;0.217)		UCEC - Uterine corpus endometrioid carcinoma (10;0.22)|OV - Ovarian serous cystadenocarcinoma(123;3.4e-08)		AGCTAGCCAGGTAGACCTGCT	0.398000													62	153					0	0	0.870114	0	0
OTOA	146183	broad.mit.edu	37	16	21698935	21698935	+	Missense_Mutation	SNP	C	C	T			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr16:21698935C>T	ENST00000388958.3	+	7	602	c.601C>T	c.(601-603)Cct>Tct	p.P201S	OTOA_ENST00000388956.4_Missense_Mutation_p.P122S|OTOA_ENST00000286149.4_Missense_Mutation_p.P201S	NM_144672.3	NP_653273.3	Q7RTW8	OTOAN_HUMAN	otoancorin	201					sensory perception of sound	anchored to membrane|apical plasma membrane|proteinaceous extracellular matrix				breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(9)|liver(2)|lung(23)|ovary(1)|prostate(1)|skin(5)|stomach(1)	46				GBM - Glioblastoma multiforme(48;0.0414)		AGAGCGGCTCCCTCGGGACCT	0.532000													24	51					0	0	0.624587	0	0
YIPF7	285525	broad.mit.edu	37	4	44631452	44631452	+	Missense_Mutation	SNP	A	A	G			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr4:44631452A>G	ENST00000332990.5	-	4	482	c.466T>C	c.(466-468)Ttt>Ctt	p.F156L		NM_182592.2	NP_872398.2	Q8N8F6	YIPF7_HUMAN	Yip1 domain family, member 7	156						endoplasmic reticulum membrane|integral to membrane				breast(1)|large_intestine(1)|lung(9)|upper_aerodigestive_tract(1)	12						GCTACGCAAAAAAGAATGGGT	0.443000													6	23					0	0	0.278610	0	0
KCNB1	3745	broad.mit.edu	37	20	47991026	47991026	+	Silent	SNP	G	G	A			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr20:47991026G>A	ENST00000371741.4	-	2	1237	c.1071C>T	c.(1069-1071)gaC>gaT	p.D357D		NM_004975.2	NP_004966.1	Q14721	KCNB1_HUMAN	potassium voltage-gated channel, Shab-related subfamily, member 1	357					energy reserve metabolic process|regulation of insulin secretion	voltage-gated potassium channel complex	protein binding|voltage-gated potassium channel activity	p.D357D(1)		central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(8)|liver(1)|lung(22)|pancreas(2)|prostate(7)|skin(4)|stomach(1)|urinary_tract(1)	53			BRCA - Breast invasive adenocarcinoma(12;0.000405)|COAD - Colon adenocarcinoma(4;0.14)|Colorectal(8;0.166)			ACTTGGTGTCGTCCTCATCCT	0.517000													5	65					0	0	0.184627	0	0
OCLN	100506658	broad.mit.edu	37	5	68840911	68840911	+	Silent	SNP	C	C	G			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr5:68840911C>G	ENST00000355237.2	+	6	1654	c.1218C>G	c.(1216-1218)ggC>ggG	p.G406G	OCLN_ENST00000396442.2_Silent_p.G406G|OCLN_ENST00000514370.1_3'UTR|OCLN_ENST00000538151.1_Silent_p.G155G|OCLN_ENST00000380766.2_Silent_p.G352G|OCLN_ENST00000542132.1_Silent_p.G84G	NM_002538.3	NP_002529.1	Q16625	OCLN_HUMAN	occludin	406					cellular component disassembly involved in apoptosis|protein complex assembly	integral to membrane|tight junction	protein binding|structural molecule activity			endometrium(2)|large_intestine(1)|liver(1)|prostate(1)|skin(1)	6		Lung NSC(167;4.15e-05)|Prostate(74;0.00996)|Ovarian(174;0.0448)|Breast(144;0.198)		OV - Ovarian serous cystadenocarcinoma(47;3.04e-60)|Epithelial(20;7.09e-58)|all cancers(19;1.13e-53)|Lung(70;0.0174)		CAACTGGCGGCGAGTCCTGTG	0.507000													27	191					0	0	0.750413	0	0
PCDH10	57575	broad.mit.edu	37	4	134072600	134072601	+	Frame_Shift_Ins	INS	-	-	C			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr4:134072600_134072601insC	ENST00000264360.4	+	1	2131_2132	c.1305_1306insC	c.(1303-1308)gcgggafs	p.AG435fs		NM_032961.1	NP_116586.1	Q9P2E7	PCD10_HUMAN	protocadherin 10	435	Cadherin 4.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding	p.A435A(1)		NS(2)|breast(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(30)|liver(1)|lung(72)|ovary(2)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(6)|urinary_tract(2)	136				LUSC - Lung squamous cell carcinoma(193;0.227)		CTGTAGTGGCTCGGGACCGGGG	0.594													9	327	---	---	---	---					
EIF3CL	728689	broad.mit.edu	37	16	28403353	28403355	+	In_Frame_Del	DEL	TCC	TCC	-			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr16:28403353_28403355delTCC	ENST00000398943.3	-	9	1021_1023	c.885_887delGGA	c.(883-888)gac>ga	p.ED295del	EIF3CL_ENST00000380876.4_In_Frame_Del_p.ED295del|EIF3CL_ENST00000398944.3_In_Frame_Del_p.ED295del					eukaryotic translation initiation factor 3, subunit C-like																		GCCTTCATTGTCCTCCTCCTCCT	0.547													3	5	---	---	---	---					
SNX29P2	440352	broad.mit.edu	37	16	29372348	29372348	+	RNA	DEL	T	T	-			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr16:29372348delT	ENST00000398878.3	+	0	1186				SNX29P2_ENST00000507381.1_RNA																							TGGGAGGttgttttttttttt	0.478													4	5	---	---	---	---					
NPIPB1P	729602	broad.mit.edu	37	18	11625378	11625379	+	RNA	INS	-	-	A	rs141097667		TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr18:11625378_11625379insA	ENST00000547442.1	-	0	621																											CTCTTCCCCCGAAAAATGACAA	0.401													3	3	---	---	---	---					
CABP7	164633	broad.mit.edu	37	22	30124615	30124621	+	Splice_Site	DEL	CCAGGTG	CCAGGTG	-			TCGA-BP-4177-01A-02D-1421-08	TCGA-BP-4177-11A-01D-1421-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ed088c23-e2ca-491b-94c0-9a5b66a1bd88	6336e23d-aedb-496b-a978-c4ad8ee66323	g.chr22:30124615_30124621delCCAGGTG	ENST00000216144.3	+	3	594_597	c.253_splice	c.e3-1	p.85_splice		NM_182527.2	NP_872333.1	Q86V35	CABP7_HUMAN	calcium binding protein 7	85	EF-hand 2.					Golgi apparatus|integral to membrane|perinuclear region of cytoplasm|plasma membrane	calcium ion binding			lung(1)|skin(3)	4			OV - Ovarian serous cystadenocarcinoma(5;0.00442)|Epithelial(10;0.215)|all cancers(5;0.233)			TGTGCCTCCACCAGGTGATGGTCAAGT	0.575													16	68	---	---	---	---					
