Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ALMS1	0	genome.wustl.edu	37	2	73613032	73613037	+	In_Frame_Del	DEL	GGAGGA	GGAGGA	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	GGAGGA	GGAGGA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	73613032	73613037	GGAGGA	-	DEL	ALMS1	ENST00000264448	human	ensembl	74_37	+1	known	in_frame_del	c.36_41	p.EE16in_frame_del	0.989:0.996:1.000:1.000:1.000:1.000	NULL	NULL	-	no_errors	ALMS1	HGNC	ENSG00000116127	tier1			NA	NA	NA	NA	NA	NA
LTBP3	0	genome.wustl.edu	37	11	65325326	65325328	+	In_Frame_Del	DEL	CAG	CAG	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	CAG	CAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	11	65325326	65325328	CAG	-	DEL	LTBP3	ENST00000301873	human	ensembl	74_37	-1	known	in_frame_del	c.105_103	p.L35in_frame_del	0.996:0.996:0.995	NULL	pfam_EGF-like_Ca-bd_dom,pfam_TB_dom,superfamily_TB_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	-	no_errors	LTBP3	HGNC	ENSG00000168056	tier1			33	0	0.00	6	2	25.00
PSG1	0	genome.wustl.edu	37	19	43383689	43383689	+	Nonsense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	19	43383689	43383689	C	T	SNP	PSG1	ENST00000312439	human	ensembl	74_37	-1	known	nonsense	c.45	p.W15*	0.024	NULL	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	PSG1	HGNC	ENSG00000231924	tier1	-	-	81	0	0.00	39	36	48.00
BEST3	0	genome.wustl.edu	37	12	70049362	70049362	+	Frame_Shift_Del	DEL	G	G	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	12	70049362	70049362	G	-	DEL	BEST3	ENST00000330891	human	ensembl	74_37	-1	known	frame_shift_del	c.1332	p.R445fs	0.001	NULL	pfam_Bestrophin/UPF0187	-	no_errors	BEST3	HGNC	ENSG00000127325	tier1			29	0	0.00	26	3	10.34
OR8B12	0	genome.wustl.edu	37	11	124413017	124413017	+	Silent	SNP	A	A	G			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	11	124413017	124413017	A	G	SNP	OR8B12	ENST00000306842	human	ensembl	74_37	-1	known	silent	c.534	p.C178	1.000	pfam_GPCR_Rhodpsn,prints_Olfact_rcpt,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,prints_Olfact_rcpt,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	OR8B12	HGNC	ENSG00000170953	tier1	-	-	33	0	0.00	24	18	42.86
PCDHA4	0	genome.wustl.edu	37	5	140186934	140186934	+	Silent	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	5	140186934	140186934	G	A	SNP	PCDHA4	ENST00000530339	human	ensembl	74_37	+1	known	silent	c.162	p.L54	1.000	pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA4	HGNC	ENSG00000204967	tier1	-	-	119	1	0.83	49	29	37.18
MAGEE2	0	genome.wustl.edu	37	X	75004715	75004715	+	Missense_Mutation	SNP	T	T	G			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	X	75004715	75004715	T	G	SNP	MAGEE2	ENST00000373359	human	ensembl	74_37	-1	known	missense	c.172	p.T58P	0.002	NULL	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEE2	HGNC	ENSG00000186675	tier1	-	-	13	0	0.00	6	6	50.00
LILRB5	0	genome.wustl.edu	37	19	54756818	54756818	+	Frame_Shift_Del	DEL	C	C	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	19	54756818	54756818	C	-	DEL	LILRB5	ENST00000450632	human	ensembl	74_37	-1	known	frame_shift_del	c.1363	p.V455fs	0.001	NULL	smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	LILRB5	HGNC	ENSG00000105609	tier1			18	0	0.00	14	2	12.50
RB1	0	genome.wustl.edu	37	13	48955394	48955394	+	Nonsense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	13	48955394	48955394	C	T	SNP	RB1	ENST00000267163	human	ensembl	74_37	+1	known	nonsense	c.1510	p.Q504*	1.000	pfam_RB_A,superfamily_Cyclin-like	pfam_RB_C,pfam_RB_A,pfam_RB_B,pfam_RB_N,superfamily_Cyclin-like,smart_Cyclin-like	-	no_errors	RB1	HGNC	ENSG00000139687	tier1	-	-	35	0	0.00	2	18	90.00
HS3ST5	0	genome.wustl.edu	37	6	114379226	114379226	+	Missense_Mutation	SNP	T	T	G			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	114379226	114379226	T	G	SNP	HS3ST5	ENST00000312719	human	ensembl	74_37	-1	known	missense	c.236	p.E79A	1.000	superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	HS3ST5	HGNC	ENSG00000249853	tier1	-	-	21	0	0.00	23	14	37.84
WDR18	0	genome.wustl.edu	37	19	991345	991345	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	19	991345	991345	C	T	SNP	WDR18	ENST00000251289	human	ensembl	74_37	+1	known	missense	c.925	p.L309F	1.000	superfamily_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep	-	no_errors	WDR18	HGNC	ENSG00000065268	tier1	-	-	26	0	0.00	1	8	88.89
XIST	0	genome.wustl.edu	37	X	73071846	73071846	+	RNA	DEL	A	A	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	X	73071846	73071846	A	-	DEL	XIST	ENST00000429829	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	XIST	HGNC	ENSG00000229807	tier1			78	0	0.00	54	7	11.48
NHLRC1	0	genome.wustl.edu	37	6	18121653	18121653	+	Frame_Shift_Del	DEL	C	C	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	18121653	18121653	C	-	DEL	NHLRC1	ENST00000340650	human	ensembl	74_37	-1	known	frame_shift_del	c.1185	p.*396fs	0.009	NULL	smart_Znf_RING,pfscan_NHL_repeat_subgr,pfscan_Znf_RING	-	no_errors	NHLRC1	HGNC	ENSG00000187566	tier1			55	0	0.00	16	2	11.11
PCDHA4	0	genome.wustl.edu	37	5	140187742	140187742	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	5	140187742	140187742	G	C	SNP	PCDHA4	ENST00000530339	human	ensembl	74_37	+1	known	missense	c.970	p.D324H	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA4	HGNC	ENSG00000204967	tier1	-	-	137	0	0.00	31	29	48.33
HS3ST5	0	genome.wustl.edu	37	6	114379227	114379227	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	114379227	114379227	C	T	SNP	HS3ST5	ENST00000312719	human	ensembl	74_37	-1	known	missense	c.235	p.E79K	1.000	superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	HS3ST5	HGNC	ENSG00000249853	tier1	-	-	21	0	0.00	21	15	41.67
WIPF1	0	genome.wustl.edu	37	2	175439998	175439998	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	175439998	175439998	G	A	SNP	WIPF1	ENST00000272746	human	ensembl	74_37	-1	known	missense	c.292	p.P98S	0.994	NULL	smart_WH2_dom,pfscan_WH2_dom	-	no_errors	WIPF1	HGNC	ENSG00000115935	tier1	-	-	55	0	0.00	20	19	48.72
SLCO1C1	0	genome.wustl.edu	37	12	20905320	20905320	+	Missense_Mutation	SNP	A	A	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	12	20905320	20905320	A	C	SNP	SLCO1C1	ENST00000381552	human	ensembl	74_37	+1	known	missense	c.2100	p.E700D	1.000	NULL	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,pfam_Sub_transporter,superfamily_MFS_dom_general_subst_transpt,tigrfam_OA_transporter	-	no_errors	SLCO1C1	HGNC	ENSG00000139155	tier1	-	-	80	0	0.00	29	26	47.27
TP53	0	genome.wustl.edu	37	17	7577540	7577540	+	Silent	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	17	7577540	7577540	G	A	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	silent	c.741	p.N247	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	44	0	0.00	7	14	66.67
RP1	0	genome.wustl.edu	37	8	55540104	55540104	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	8	55540104	55540104	C	T	SNP	RP1	ENST00000220676	human	ensembl	74_37	+1	known	missense	c.3662	p.P1221L	0.001	NULL	pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom	-	no_errors	RP1	HGNC	ENSG00000104237	tier1	-	-	16	0	0.00	16	8	33.33
ENSG00000272769	0	genome.wustl.edu	37	2	133103903	133103903	+	RNA	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	133103903	133103903	C	T	SNP	ENSG00000272769	ENST00000608279	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.006	-	-	-	no_errors	RP11-725P16.2	Clone_based_vega_gene	ENSG00000272769	tier1	rs6430238	-	18	0	0.00	16	12	42.86
TFRC	0	genome.wustl.edu	37	3	195785483	195785483	+	Silent	SNP	C	C	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	3	195785483	195785483	C	A	SNP	TFRC	ENST00000360110	human	ensembl	74_37	-1	known	silent	c.1557	p.G519	0.000	pfam_Peptidase_M28	pfam_TFR-like_dimer_dom,pfam_Peptidase_M28,pfam_Protease-assoc_domain,superfamily_TFR-like_dimer_dom	-	no_errors	TFRC	HGNC	ENSG00000072274	tier1	-	-	83	0	0.00	53	34	39.08
TMEM60	0	genome.wustl.edu	37	7	77423460	77423460	+	Frame_Shift_Del	DEL	T	T	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	7	77423460	77423460	T	-	DEL	TMEM60	ENST00000257663	human	ensembl	74_37	-1	known	frame_shift_del	c.231	p.A78fs	0.998	NULL	pfam_TM_Fragile-X-F-assoc	-	no_errors	TMEM60	HGNC	ENSG00000135211	tier1			74	0	0.00	22	3	12.00
KPNA6	0	genome.wustl.edu	37	1	32625019	32625019	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	1	32625019	32625019	C	T	SNP	KPNA6	ENST00000545542	human	ensembl	74_37	+1	known	silent	c.460	p.L154	1.000	pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	pfam_Armadillo,pfam_Importin-a_IBB,pfam_HEAT,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo,pfscan_Importin-a_IBB	-	no_errors	KPNA6	HGNC	ENSG00000025800	tier1	-	-	41	0	0.00	37	14	27.45
ENSG00000256616	0	genome.wustl.edu	37	18	12076541	12076542	+	RNA	INS	-	-	CGCCGCCGCCGC			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	18	12076541	12076542	-	CGCCGCCGCCGC	INS	ENSG00000256616	ENST00000591780	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.834:0.844	-	-	-	no_errors	RP11-815J4.6	Clone_based_vega_gene	ENSG00000256616	tier1			NA	NA	NA	NA	NA	NA
JAKMIP1	0	genome.wustl.edu	37	4	6066655	6066655	+	Silent	SNP	T	T	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	4	6066655	6066655	T	C	SNP	JAKMIP1	ENST00000409021	human	ensembl	74_37	-1	known	silent	c.1383	p.T461	0.107	NULL	NULL	-	no_errors	JAKMIP1	HGNC	ENSG00000152969	tier1	-	-	91	0	0.00	48	25	34.25
TCEA2	0	genome.wustl.edu	37	20	62699436	62699436	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	20	62699436	62699436	G	A	SNP	TCEA2	ENST00000343484	human	ensembl	74_37	+1	known	missense	c.278	p.G93D	0.625	superfamily_TFIIS_N,pirsf_TF_IIS-rel,tigrfam_TFSII	pfam_TFIIS_cen_dom,pfam_TFIIS_N,pfam_Znf_TFIIS,superfamily_TFIIS_cen_dom,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub,smart_TFS2M,smart_Znf_TFIIS,pirsf_TF_IIS-rel,pfscan_Znf_TFIIS,tigrfam_TFSII	-	no_errors	TCEA2	HGNC	ENSG00000171703	tier1	-	-	47	0	0.00	14	9	39.13
CENPE	0	genome.wustl.edu	37	4	104084678	104084678	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	4	104084678	104084678	C	T	SNP	CENPE	ENST00000265148	human	ensembl	74_37	-1	known	silent	c.1680	p.K560	1.000	NULL	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,superfamily_STAT_TF_coiled-coil,superfamily_Signal_recog_particl_SRP54_hlx,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	CENPE	HGNC	ENSG00000138778	tier1	-	-	43	0	0.00	42	13	23.64
LTBP2	0	genome.wustl.edu	37	14	74995277	74995277	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	14	74995277	74995277	C	T	SNP	LTBP2	ENST00000261978	human	ensembl	74_37	-1	known	silent	c.2277	p.R759	0.995	NULL	pfam_EGF-like_Ca-bd_dom,pfam_TB_dom,pfam_EG-like_dom,superfamily_TB_dom,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	-	no_errors	LTBP2	HGNC	ENSG00000119681	tier1	-	-	47	0	0.00	20	25	55.56
KIAA2018	0	genome.wustl.edu	37	3	113377481	113377482	+	Frame_Shift_Ins	INS	-	-	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	3	113377481	113377482	-	T	INS	KIAA2018	ENST00000316407	human	ensembl	74_37	-1	known	frame_shift_ins	c.3048_3047	p.N1016fs	0.174:0.827	NULL	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	KIAA2018	HGNC	ENSG00000176542	tier1			21	0	0.00	33	6	15.38
PALMD	0	genome.wustl.edu	37	1	100154947	100154947	+	Silent	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	1	100154947	100154947	G	A	SNP	PALMD	ENST00000263174	human	ensembl	74_37	+1	known	silent	c.1131	p.G377	0.074	NULL	pfam_Paralemmin	-	no_errors	PALMD	HGNC	ENSG00000099260	tier1	-	-	22	0	0.00	26	15	36.59
COTL1	0	genome.wustl.edu	37	16	84651171	84651171	+	Silent	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	16	84651171	84651171	G	A	SNP	COTL1	ENST00000262428	human	ensembl	74_37	-1	known	silent	c.96	p.D32	1.000	pfam_Actin-bd_cofilin/tropomyosin,smart_Actin-bd_cofilin/tropomyosin	pfam_Actin-bd_cofilin/tropomyosin,smart_Actin-bd_cofilin/tropomyosin	-	no_errors	COTL1	HGNC	ENSG00000103187	tier1	-	-	100	0	0.00	33	4	10.81
RSPO1	0	genome.wustl.edu	37	1	38082190	38082190	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	1	38082190	38082190	G	T	SNP	RSPO1	ENST00000356545	human	ensembl	74_37	-1	known	missense	c.252	p.F84L	0.928	superfamily_Growth_fac_rcpt_N_dom,smart_Furin_repeat	pfam_Thrombospondin_1_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_Thrombospondin_1_rpt,smart_Furin_repeat,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	-	no_errors	RSPO1	HGNC	ENSG00000169218	tier1	-	-	25	0	0.00	18	5	21.74
MALAT1	0	genome.wustl.edu	37	11	65273756	65273766	+	RNA	DEL	TGAACTATATA	TGAACTATATA	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	TGAACTATATA	TGAACTATATA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	11	65273756	65273766	TGAACTATATA	-	DEL	MALAT1	ENST00000534336	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000:0.001:0.001:0.000:0.000:0.000:0.000:0.000:0.000:0.000	-	-	-	no_errors	MALAT1	HGNC	ENSG00000251562	tier1			NA	NA	NA	NA	NA	NA
GTSF1	0	genome.wustl.edu	37	12	54856510	54856510	+	Splice_Site	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	12	54856510	54856510	C	T	SNP	GTSF1	ENST00000546931	human	ensembl	74_37	-1	known	splice_site	c.245-1	e4-1	1.000	-	-	-	no_errors	GTSF1	HGNC	ENSG00000170627	tier1	-	-	50	0	0.00	38	4	9.52
EPS15L1	0	genome.wustl.edu	37	19	16539564	16539564	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	19	16539564	16539564	G	C	SNP	EPS15L1	ENST00000455140	human	ensembl	74_37	-1	known	missense	c.507	p.D169E	0.999	smart_EPS15_homology,smart_EF_hand_dom,pfscan_EF_hand_dom,pfscan_EPS15_homology	superfamily_Prefoldin,smart_EPS15_homology,smart_EF_hand_dom,smart_Ubiquitin-int_motif,pfscan_EF_hand_dom,pfscan_EPS15_homology,pfscan_Ubiquitin-int_motif	-	no_errors	EPS15L1	HGNC	ENSG00000127527	tier1	-	-	54	0	0.00	20	14	41.18
PARP4	0	genome.wustl.edu	37	13	25021323	25021323	+	Missense_Mutation	SNP	A	A	G			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	13	25021323	25021323	A	G	SNP	PARP4	ENST00000381989	human	ensembl	74_37	-1	known	missense	c.3116	p.I1039T	1.000	pfam_VWF_A,pfscan_VWF_A	pfam_Poly(ADP-ribose)pol_cat_dom,pfam_VIT,pfam_VWF_A,pfam_BRCT_dom,superfamily_Poly(ADP-ribose)pol_reg_dom,superfamily_BRCT_dom,smart_BRCT_dom,smart_VIT,smart_VWF_A,pfscan_BRCT_dom,pfscan_VWF_A,pfscan_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_reg_dom	-	no_errors	PARP4	HGNC	ENSG00000102699	tier1	rs73172125	-	27	0	0.00	23	7	23.33
LRP12	0	genome.wustl.edu	37	8	105510059	105510059	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	8	105510059	105510059	C	T	SNP	LRP12	ENST00000424843	human	ensembl	74_37	-1	known	missense	c.664	p.G222R	1.000	pfam_LDrepeatLR_classA_rpt,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	pfam_CUB_dom,pfam_LDrepeatLR_classA_rpt,superfamily_CUB_dom,superfamily_LDrepeatLR_classA_rpt,smart_CUB_dom,smart_LDrepeatLR_classA_rpt,pfscan_CUB_dom,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP12	HGNC	ENSG00000147650	tier1	-	-	31	0	0.00	19	18	48.65
EFCAB6	0	genome.wustl.edu	37	22	43972249	43972249	+	Frame_Shift_Del	DEL	T	T	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	22	43972249	43972249	T	-	DEL	EFCAB6	ENST00000262726	human	ensembl	74_37	-1	known	frame_shift_del	c.3348	p.K1116fs	0.144	NULL	pfam_EF_hand_Ca-bd_contain_6,smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	EFCAB6	HGNC	ENSG00000186976	tier1			66	0	0.00	59	25	29.76
FFAR3	0	genome.wustl.edu	37	19	35850190	35850190	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	19	35850190	35850190	G	A	SNP	FFAR3	ENST00000327809	human	ensembl	74_37	+1	known	missense	c.398	p.G133D	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_GPR40-rel_orph	-	no_errors	FFAR3	HGNC	ENSG00000185897	tier1	rs144435503	-	16	0	0.00	9	6	40.00
LRTM2	0	genome.wustl.edu	37	12	1943471	1943471	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	12	1943471	1943471	G	A	SNP	LRTM2	ENST00000299194	human	ensembl	74_37	+1	known	missense	c.697	p.E233K	1.000	smart_Cys-rich_flank_reg_C	pfam_Leu-rich_rpt,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C	-	no_errors	LRTM2	HGNC	ENSG00000166159	tier1	-	-	60	0	0.00	24	19	44.19
ALAS2	0	genome.wustl.edu	37	X	55044015	55044015	+	Missense_Mutation	SNP	T	T	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	X	55044015	55044015	T	C	SNP	ALAS2	ENST00000330807	human	ensembl	74_37	-1	known	missense	c.907	p.R303G	1.000	pfam_Aminotransferase_I/II,pfam_Aminotrans_V/Cys_dSase,pfam_Cys/Met-Metab_PyrdxlP-dep_enz,superfamily_PyrdxlP-dep_Trfase,tigrfam_4pyrrol_synth_NH2levulA_synth	pfam_Aminotransferase_I/II,pfam_5aminolev_synth_preseq,pfam_Aminotrans_V/Cys_dSase,pfam_Cys/Met-Metab_PyrdxlP-dep_enz,superfamily_PyrdxlP-dep_Trfase,tigrfam_4pyrrol_synth_NH2levulA_synth	-	no_errors	ALAS2	HGNC	ENSG00000158578	tier1	-	-	38	0	0.00	46	4	8.00
TTK	0	genome.wustl.edu	37	6	80751896	80751897	+	Frame_Shift_Ins	INS	-	-	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	80751896	80751897	-	A	INS	TTK	ENST00000369798	human	ensembl	74_37	+1	known	frame_shift_ins	c.2551_2552	p.R854fs	0.178:0.102	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	TTK	HGNC	ENSG00000112742	tier1			34	0	0.00	57	5	8.06
DIS3L2	0	genome.wustl.edu	37	2	233127950	233127950	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	233127950	233127950	C	T	SNP	DIS3L2	ENST00000325385	human	ensembl	74_37	+1	known	missense	c.1459	p.R487C	0.946	NULL	NULL	-	no_errors	DIS3L2	HGNC	ENSG00000144535	tier1	-	-	34	0	0.00	24	17	41.46
VSTM4	0	genome.wustl.edu	37	10	50285292	50285292	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	10	50285292	50285292	C	T	SNP	VSTM4	ENST00000332853	human	ensembl	74_37	-1	known	silent	c.606	p.Q202	1.000	NULL	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	VSTM4	HGNC	ENSG00000165633	tier1	-	-	26	0	0.00	16	3	15.00
CNTNAP5	0	genome.wustl.edu	37	2	124999804	124999804	+	Missense_Mutation	SNP	C	C	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	124999804	124999804	C	A	SNP	CNTNAP5	ENST00000431078	human	ensembl	74_37	+1	known	missense	c.215	p.S72Y	1.000	pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,smart_Coagulation_fac_5/8-C_type_dom,pfscan_Coagulation_fac_5/8-C_type_dom	pfam_Laminin_G,pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,superfamily_ConA-like_lec_gl_sf,superfamily_Fibrinogen_a/b/g_C_dom,smart_Coagulation_fac_5/8-C_type_dom,smart_Laminin_G,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Coagulation_fac_5/8-C_type_dom,pfscan_Laminin_G	-	no_errors	CNTNAP5	HGNC	ENSG00000155052	tier1	-	-	31	0	0.00	28	31	52.54
PRPF40B	0	genome.wustl.edu	37	12	50036074	50036074	+	Silent	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	12	50036074	50036074	G	A	SNP	PRPF40B	ENST00000548825	human	ensembl	74_37	+1	known	silent	c.1941	p.R647	1.000	NULL	pfam_FF_domain,pfam_WW_dom,superfamily_FF_domain,superfamily_WW_dom,smart_WW_dom,smart_FF_domain,pfscan_WW_dom	-	no_errors	PRPF40B	HGNC	ENSG00000110844	tier1	rs148666758	-	9	0	0.00	9	4	30.77
ACSF2	0	genome.wustl.edu	37	17	48551285	48551285	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	17	48551285	48551285	G	A	SNP	ACSF2	ENST00000300441	human	ensembl	74_37	+1	known	missense	c.1648	p.E550K	1.000	NULL	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSF2	HGNC	ENSG00000167107	tier1	-	-	51	0	0.00	44	4	8.33
MALAT1	0	genome.wustl.edu	37	11	65273750	65273777	+	RNA	DEL	TATCTTTGAACTATATACATCCTTGATG	TATCTTTGAACTATATACATCCTTGATG	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	TATCTTTGAACTATATACATCCTTGATG	TATCTTTGAACTATATACATCCTTGATG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	11	65273750	65273777	TATCTTTGAACTATATACATCCTTGATG	-	DEL	MALAT1	ENST00000534336	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.001:0.000:0.000:0.000:0.000:0.000:0.000:0.001:0.001:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.001:0.000:0.000:0.000:0.000:0.000:0.000:0.000	-	-	-	no_errors	MALAT1	HGNC	ENSG00000251562	tier1			NA	NA	NA	NA	NA	NA
PRPF40B	0	genome.wustl.edu	37	12	50036073	50036073	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	12	50036073	50036073	G	A	SNP	PRPF40B	ENST00000548825	human	ensembl	74_37	+1	known	missense	c.1940	p.R647K	1.000	NULL	pfam_FF_domain,pfam_WW_dom,superfamily_FF_domain,superfamily_WW_dom,smart_WW_dom,smart_FF_domain,pfscan_WW_dom	-	no_errors	PRPF40B	HGNC	ENSG00000110844	tier1	-	-	9	0	0.00	9	4	30.77
TAF7L	0	genome.wustl.edu	37	X	100531459	100531461	+	In_Frame_Del	DEL	TCA	TCA	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	TCA	TCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	X	100531459	100531461	TCA	-	DEL	TAF7L	ENST00000372907	human	ensembl	74_37	-1	known	in_frame_del	c.1007_1005	p.D335in_frame_del	0.009:0.005:0.000	NULL	pfam_TAFII55_prot_cons_reg	-	no_errors	TAF7L	HGNC	ENSG00000102387	tier1			14	0	0.00	22	2	8.33
KIAA1551	0	genome.wustl.edu	37	12	32134974	32134974	+	Missense_Mutation	SNP	A	A	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	12	32134974	32134974	A	C	SNP	KIAA1551	ENST00000312561	human	ensembl	74_37	+1	known	missense	c.1085	p.Q362P	0.000	NULL	NULL	-	no_errors	KIAA1551	HGNC	ENSG00000174718	tier1	-	-	51	0	0.00	44	22	33.33
C22orf34	0	genome.wustl.edu	37	22	49834816	49834816	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	22	49834816	49834816	C	T	SNP	C22orf34	ENST00000414287	human	ensembl	74_37	-1	known	missense	c.101	p.R34K	0.000	NULL	NULL	-	no_errors	C22orf34	HGNC	ENSG00000188511	tier1	-	-	47	0	0.00	18	15	45.45
MALAT1	0	genome.wustl.edu	37	11	65273769	65273785	+	RNA	DEL	TCCTTGATGTATAATTT	TCCTTGATGTATAATTT	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	TCCTTGATGTATAATTT	TCCTTGATGTATAATTT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	11	65273769	65273785	TCCTTGATGTATAATTT	-	DEL	MALAT1	ENST00000534336	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.001:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.001	-	-	-	no_errors	MALAT1	HGNC	ENSG00000251562	tier1			NA	NA	NA	NA	NA	NA
HRNR	0	genome.wustl.edu	37	1	152192912	152192912	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	1	152192912	152192912	G	A	SNP	HRNR	ENST00000368801	human	ensembl	74_37	-1	known	missense	c.1193	p.S398F	0.002	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom	-	no_errors	HRNR	HGNC	ENSG00000197915	tier1	-	-	30	0	0.00	28	12	30.00
ACAN	0	genome.wustl.edu	37	15	89398253	89398253	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	15	89398253	89398253	C	T	SNP	ACAN	ENST00000439576	human	ensembl	74_37	+1	known	missense	c.2437	p.P813S	0.039	NULL	pfam_Link,pfam_C-type_lectin,pfam_Ig_V-set,pfam_Sushi_SCR_CCP,pfam_EG-like_dom,superfamily_C-type_lectin_fold,superfamily_Sushi_SCR_CCP,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Link,smart_EG-like_dom,smart_C-type_lectin,smart_Sushi_SCR_CCP,pfscan_EG-like_dom,pfscan_C-type_lectin,pfscan_Link,pfscan_Sushi_SCR_CCP,pfscan_Ig-like_dom,prints_Link	-	no_errors	ACAN	HGNC	ENSG00000157766	tier1	-	-	55	0	0.00	47	32	40.51
TRIM27	0	genome.wustl.edu	37	6	28871977	28871977	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	28871977	28871977	C	T	SNP	TRIM27	ENST00000377199	human	ensembl	74_37	-1	known	missense	c.1412	p.R471Q	1.000	pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,prints_Butyrophylin	pfam_SPRY_rcpt,pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin,prints_Znf_B-box_chordata	-	no_errors	TRIM27	HGNC	ENSG00000204713	tier1	-	-	35	0	0.00	23	4	14.81
LRP12	0	genome.wustl.edu	37	8	105510058	105510058	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	8	105510058	105510058	C	T	SNP	LRP12	ENST00000424843	human	ensembl	74_37	-1	known	missense	c.665	p.G222E	1.000	pfam_LDrepeatLR_classA_rpt,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	pfam_CUB_dom,pfam_LDrepeatLR_classA_rpt,superfamily_CUB_dom,superfamily_LDrepeatLR_classA_rpt,smart_CUB_dom,smart_LDrepeatLR_classA_rpt,pfscan_CUB_dom,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP12	HGNC	ENSG00000147650	tier1	-	-	32	0	0.00	19	17	47.22
KIAA1549L	0	genome.wustl.edu	37	11	33628349	33628349	+	Missense_Mutation	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	11	33628349	33628349	C	T	SNP	KIAA1549L	ENST00000389726	human	ensembl	74_37	+1	known	missense	c.4169	p.S1390L	0.868	NULL	NULL	-	no_errors	KIAA1549L	HGNC	ENSG00000110427	tier1	-	-	35	0	0.00	41	7	14.58
PLXNB2	0	genome.wustl.edu	37	22	50717058	50717058	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	22	50717058	50717058	C	T	SNP	PLXNB2	ENST00000359337	human	ensembl	74_37	-1	known	silent	c.4614	p.R1538	0.909	pfam_Plexin_cytoplasmic_RasGAP_dom,superfamily_Rho_GTPase_activation_prot	pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_IPT,pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom	-	no_errors	PLXNB2	HGNC	ENSG00000196576	tier1	-	-	66	0	0.00	27	21	43.75
LHX1	0	genome.wustl.edu	37	17	35299571	35299571	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	17	35299571	35299571	C	T	SNP	LHX1	ENST00000254457	human	ensembl	74_37	+1	known	silent	c.750	p.A250	1.000	NULL	pfam_Znf_LIM,pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Znf_LIM,smart_Homeobox_dom,pfscan_Znf_LIM,pfscan_Homeobox_dom	-	no_errors	LHX1	HGNC	ENSG00000132130	tier1	-	-	22	0	0.00	5	3	37.50
ANGPT4	0	genome.wustl.edu	37	20	853735	853735	+	Silent	SNP	T	T	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	20	853735	853735	T	A	SNP	ANGPT4	ENST00000381922	human	ensembl	74_37	-1	known	silent	c.1380	p.S460	1.000	pfam_Fibrinogen_a/b/g_C_dom,superfamily_Fibrinogen_a/b/g_C_dom,smart_Fibrinogen_a/b/g_C_dom	pfam_Fibrinogen_a/b/g_C_dom,superfamily_Fibrinogen_a/b/g_C_dom,smart_Fibrinogen_a/b/g_C_dom	-	no_errors	ANGPT4	HGNC	ENSG00000101280	tier1	-	-	27	0	0.00	18	11	37.93
TG	0	genome.wustl.edu	37	8	133931621	133931621	+	Missense_Mutation	SNP	T	T	G			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	8	133931621	133931621	T	G	SNP	TG	ENST00000220616	human	ensembl	74_37	+1	known	missense	c.4379	p.V1460G	0.945	pirsf_Thyroglobulin	pfam_Thyroglobulin_1,pfam_CarbesteraseB,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Thyroglobulin_1,smart_Thyroglobulin_1,pirsf_Thyroglobulin,pfscan_Thyroglobulin_1	-	no_errors	TG	HGNC	ENSG00000042832	tier1	-	-	34	0	0.00	27	22	44.90
PCDHA4	0	genome.wustl.edu	37	5	140188483	140188483	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	5	140188483	140188483	G	C	SNP	PCDHA4	ENST00000530339	human	ensembl	74_37	+1	known	missense	c.1711	p.G571R	0.007	superfamily_Cadherin-like	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA4	HGNC	ENSG00000204967	tier1	-	-	110	0	0.00	34	23	40.35
DOCK7	0	genome.wustl.edu	37	1	63113413	63113413	+	Missense_Mutation	SNP	A	A	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	1	63113413	63113413	A	T	SNP	DOCK7	ENST00000251157	human	ensembl	74_37	-1	known	missense	c.767	p.I256K	1.000	NULL	pfam_DOCK_C,pfam_DOCK_C/D_N,superfamily_ARM-type_fold	-	no_errors	DOCK7	HGNC	ENSG00000116641	tier1	-	-	114	0	0.00	80	43	34.96
LOC101927648	0	genome.wustl.edu	37	1	143355542	143355542	+	RNA	SNP	C	C	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	1	143355542	143355542	C	A	SNP	LOC101927648	ENST00000423249	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	RP11-435B5.4	Clone_based_vega_gene	ENSG00000185044	tier1	rs186013055	-	18	0	0.00	15	8	34.78
PIWIL2	0	genome.wustl.edu	37	8	22145080	22145080	+	Silent	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	8	22145080	22145080	G	A	SNP	PIWIL2	ENST00000356766	human	ensembl	74_37	+1	known	silent	c.783	p.L261	1.000	superfamily_PAZ_dom	pfam_Piwi,pfam_PAZ_dom,superfamily_RNaseH-like_dom,superfamily_PAZ_dom,smart_PAZ_dom,smart_Piwi,pfscan_PAZ_dom,pfscan_Piwi	-	no_errors	PIWIL2	HGNC	ENSG00000197181	tier1	-	-	60	0	0.00	32	19	37.25
ZNF552	0	genome.wustl.edu	37	19	58325967	58325967	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	19	58325967	58325967	G	A	SNP	ZNF552	ENST00000596248	human	ensembl	74_37	-1	known	missense	c.145	p.H49Y	0.000	NULL	NULL	-	no_errors	ZNF552	HGNC	ENSG00000178935	tier1	-	-	61	0	0.00	19	6	24.00
DIS3L2	0	genome.wustl.edu	37	2	233127949	233127949	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	233127949	233127949	C	G	SNP	DIS3L2	ENST00000325385	human	ensembl	74_37	+1	known	missense	c.1458	p.I486M	0.957	NULL	NULL	-	no_errors	DIS3L2	HGNC	ENSG00000144535	tier1	-	-	33	0	0.00	23	17	42.50
PLCE1	0	genome.wustl.edu	37	10	96014797	96014797	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	10	96014797	96014797	G	A	SNP	PLCE1	ENST00000260766	human	ensembl	74_37	+1	known	missense	c.3545	p.S1182N	1.000	NULL	pfam_PLipase_C_PInositol-sp_X_dom,pfam_PLipase_C_Pinositol-sp_Y,pfam_Ras-assoc,pfam_RasGRF_CDC25,pfam_PLipase_C_EF-hand-like,pfam_C2_dom,superfamily_PLC-like_Pdiesterase_TIM-brl,superfamily_Ras_GEF_dom,superfamily_C2_dom,smart_RasGRF_CDC25,smart_PLipase_C_PInositol-sp_X_dom,smart_PLipase_C_Pinositol-sp_Y,smart_C2_dom,smart_Ras-assoc,pfscan_C2_dom,pfscan_Ras-assoc,pfscan_PLipase_C_PInositol-sp_X_dom,pfscan_PLipase_C_Pinositol-sp_Y,pfscan_RasGRF_CDC25,prints_Pinositol_PLipase_C	-	no_errors	PLCE1	HGNC	ENSG00000138193	tier1	-	-	19	0	0.00	6	7	53.85
PDLIM2	0	genome.wustl.edu	37	8	22451416	22451416	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	8	22451416	22451416	G	A	SNP	PDLIM2	ENST00000308354	human	ensembl	74_37	+1	known	missense	c.1802	p.R601Q	0.192	NULL	pfam_PDZ,pfam_Znf_LIM,superfamily_PDZ,smart_PDZ,smart_Znf_LIM,pfscan_Znf_LIM,pfscan_PDZ	-	no_errors	PDLIM2	HGNC	ENSG00000120913	tier1	rs150050587	GMAF=0.0005	55	0	0.00	22	7	24.14
MYH8	0	genome.wustl.edu	37	17	10303854	10303854	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	17	10303854	10303854	C	T	SNP	MYH8	ENST00000403437	human	ensembl	74_37	-1	known	silent	c.3588	p.R1196	0.976	pfam_Myosin_tail	pfam_Myosin_tail,pfam_Myosin_head_motor_dom,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,superfamily_t-SNARE,smart_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH8	HGNC	ENSG00000133020	tier1	-	-	40	0	0.00	4	9	64.29
PAXIP1	0	genome.wustl.edu	37	7	154760325	154760327	+	In_Frame_Del	DEL	TGC	TGC	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	TGC	TGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	7	154760325	154760327	TGC	-	DEL	PAXIP1	ENST00000397192	human	ensembl	74_37	-1	known	in_frame_del	c.1586_1584	p.Q531in_frame_del	1.000:1.000:0.993	NULL	pfam_BRCT_dom,superfamily_BRCT_dom,smart_BRCT_dom,pfscan_BRCT_dom	-	no_errors	PAXIP1	HGNC	ENSG00000157212	tier1			37	0	0.00	14	4	22.22
NUP153	0	genome.wustl.edu	37	6	17633077	17633078	+	Splice_Site	INS	-	-	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	17633077	17633078	-	A	INS	NUP153	ENST00000537253	human	ensembl	74_37	-1	known	splice_site_ins	c.2558-3_2558-2	e18-2	0.970:0.138	-	-	-	no_errors	NUP153	HGNC	ENSG00000124789	tier1			50	0	0.00	30	4	11.76
PCDHA4	0	genome.wustl.edu	37	5	140187703	140187703	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	5	140187703	140187703	G	A	SNP	PCDHA4	ENST00000530339	human	ensembl	74_37	+1	known	missense	c.931	p.E311K	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA4	HGNC	ENSG00000204967	tier1	-	-	133	0	0.00	31	30	49.18
WWC1	0	genome.wustl.edu	37	5	167719216	167719216	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	5	167719216	167719216	G	A	SNP	WWC1	ENST00000265293	human	ensembl	74_37	+1	known	missense	c.59	p.G20D	1.000	pfam_WW_dom,superfamily_WW_dom,smart_WW_dom,pfscan_WW_dom	pfam_WW_dom,superfamily_C2_dom,superfamily_WW_dom,smart_WW_dom,pfscan_WW_dom	-	no_errors	WWC1	HGNC	ENSG00000113645	tier1	-	-	30	0	0.00	26	4	13.33
DNAH8	0	genome.wustl.edu	37	6	38704933	38704933	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	38704933	38704933	G	A	SNP	DNAH8	ENST00000359357	human	ensembl	74_37	+1	known	missense	c.202	p.A68T	1.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH8	HGNC	ENSG00000124721	tier1	-	-	49	0	0.00	31	4	11.43
TSPYL4	0	genome.wustl.edu	37	6	116574621	116574621	+	Frame_Shift_Del	DEL	T	T	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	6	116574621	116574621	T	-	DEL	TSPYL4	ENST00000420283	human	ensembl	74_37	-1	known	frame_shift_del	c.551	p.K184fs	0.135	NULL	pfam_NAP_family	-	no_errors	TSPYL4	HGNC	ENSG00000187189	tier1			29	0	0.00	35	4	10.26
NT5DC4	0	genome.wustl.edu	37	2	113479458	113479458	+	Silent	SNP	C	C	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	113479458	113479458	C	T	SNP	NT5DC4	ENST00000327581	human	ensembl	74_37	+1	novel	silent	c.75	p.Y25	1.000	pfam_HAD-SF_hydro_IG_5-nucl,superfamily_HAD-like_dom,tigrfam_HAD-SF_hydro_IG_5-nucl	pfam_HAD-SF_hydro_IG_5-nucl,superfamily_HAD-like_dom,tigrfam_HAD-SF_hydro_IG_5-nucl	-	no_errors	NT5DC4	HGNC	ENSG00000144130	tier1	-	-	27	0	0.00	32	4	11.11
PCDHA4	0	genome.wustl.edu	37	5	140187574	140187574	+	Missense_Mutation	SNP	G	G	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	5	140187574	140187574	G	C	SNP	PCDHA4	ENST00000530339	human	ensembl	74_37	+1	known	missense	c.802	p.D268H	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA4	HGNC	ENSG00000204967	tier1	-	-	74	0	0.00	23	21	47.73
THAP4	0	genome.wustl.edu	37	2	242573427	242573427	+	Missense_Mutation	SNP	G	G	T			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	242573427	242573427	G	T	SNP	THAP4	ENST00000407315	human	ensembl	74_37	-1	known	missense	c.145	p.P49T	0.994	pfam_Znf_C2CH,smart_Znf_C2CH,pfscan_Znf_C2CH	pfam_DUF1794,pfam_Znf_C2CH,superfamily_Calycin-like,smart_Znf_C2CH,pfscan_Znf_C2CH	-	no_errors	THAP4	HGNC	ENSG00000176946	tier1	-	-	122	0	0.00	32	23	41.82
TCEA2	0	genome.wustl.edu	37	20	62699435	62699435	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	20	62699435	62699435	G	A	SNP	TCEA2	ENST00000343484	human	ensembl	74_37	+1	known	missense	c.277	p.G93S	0.725	superfamily_TFIIS_N,pirsf_TF_IIS-rel,tigrfam_TFSII	pfam_TFIIS_cen_dom,pfam_TFIIS_N,pfam_Znf_TFIIS,superfamily_TFIIS_cen_dom,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub,smart_TFS2M,smart_Znf_TFIIS,pirsf_TF_IIS-rel,pfscan_Znf_TFIIS,tigrfam_TFSII	-	no_errors	TCEA2	HGNC	ENSG00000171703	tier1	-	-	48	0	0.00	15	8	34.78
OTOF	0	genome.wustl.edu	37	2	26707374	26707374	+	Missense_Mutation	SNP	C	C	G			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	26707374	26707374	C	G	SNP	OTOF	ENST00000272371	human	ensembl	74_37	-1	known	missense	c.1173	p.K391N	1.000	pfam_FerIin-domain	pfam_C2_dom,pfam_Ferlin_B-domain,pfam_FerIin-domain,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	-	no_errors	OTOF	HGNC	ENSG00000115155	tier1	-	-	54	0	0.00	4	24	85.71
KRTAP13-1	0	genome.wustl.edu	37	21	31768501	31768501	+	Missense_Mutation	SNP	A	A	C			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	21	31768501	31768501	A	C	SNP	KRTAP13-1	ENST00000355459	human	ensembl	74_37	+1	known	missense	c.97	p.N33H	0.004	pfam_KRTAP_PMG	pfam_KRTAP_PMG	-	no_errors	KRTAP13-1	HGNC	ENSG00000198390	tier1	-	-	27	0	0.00	23	16	41.03
LIPA	0	genome.wustl.edu	37	10	90988006	90988006	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	10	90988006	90988006	G	A	SNP	LIPA	ENST00000336233	human	ensembl	74_37	-1	known	missense	c.379	p.R127W	1.000	pfam_AB_hydrolase_1	pfam_AB_hydrolase_1,pfam_AB_hydrolase_lipase	-	no_errors	LIPA	HGNC	ENSG00000107798	tier1	rs140686447	-	48	0	0.00	7	26	78.79
ALPP	0	genome.wustl.edu	37	2	233243529	233243531	+	In_Frame_Del	DEL	TGC	TGC	-			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	TGC	TGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	2	233243529	233243531	TGC	-	DEL	ALPP	ENST00000392027	human	ensembl	74_37	+1	known	in_frame_del	c.17_19	p.L10in_frame_del	0.645:0.641:0.627	NULL	pfam_Alkaline_phosphatase,superfamily_Alkaline_phosphatase_core,smart_Alkaline_phosphatase,prints_Alkaline_phosphatase	-	no_errors	ALPP	HGNC	ENSG00000163283	tier1			95	0	0.00	84	9	9.68
TP53	0	genome.wustl.edu	37	17	7577539	7577539	+	Missense_Mutation	SNP	G	G	A			TCGA-3B-A9HY-01A-11D-A38Z-09	TCGA-3B-A9HY-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	588bb1bf-5859-4649-b7f2-4b1eb2e85078	0785de42-153c-44f5-8af2-74b38a93a637	17	7577539	7577539	G	A	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.742	p.R248W	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	rs121912651	-	44	0	0.00	5	16	76.19
