Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ANK3	0	genome.wustl.edu	37	10	61833091	61833091	+	Silent	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	10	61833091	61833091	G	T	SNP	ANK3	ENST00000280772	human	ensembl	74_37	-1	known	silent	c.7548	p.S2516	1.000	NULL	pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt	-	no_errors	ANK3	HGNC	ENSG00000151150	tier1	-	-	45	0	0.00	46	4	8.00
TTC39B	0	genome.wustl.edu	37	9	15211327	15211327	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	9	15211327	15211327	A	T	SNP	TTC39B	ENST00000512701	human	ensembl	74_37	-1	known	missense	c.551	p.F184Y	1.000	pfam_OMP_IML2_mit/TPR_39	pfam_OMP_IML2_mit/TPR_39,smart_TPR_repeat	-	no_errors	TTC39B	HGNC	ENSG00000155158	tier1	-	-	46	0	0.00	29	17	36.96
EIF2AK3	0	genome.wustl.edu	37	2	88885426	88885426	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	88885426	88885426	G	A	SNP	EIF2AK3	ENST00000303236	human	ensembl	74_37	-1	known	missense	c.1583	p.T528M	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Quinonprotein_ADH-like_supfam,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	EIF2AK3	HGNC	ENSG00000172071	tier1	rs200171164	-	115	0	0.00	55	25	30.86
TMEM211	0	genome.wustl.edu	37	22	25331358	25331358	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	22	25331358	25331358	G	T	SNP	TMEM211	ENST00000423535	human	ensembl	74_37	-1	known	missense	c.545	p.T182N	0.024	NULL	pfam_Lipome_HGMIC_fus_partner-like	-	no_errors	TMEM211	HGNC	ENSG00000206069	tier1	-	-	34	0	0.00	10	6	37.50
ALMS1	0	genome.wustl.edu	37	2	73827825	73827825	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	73827825	73827825	G	A	SNP	ALMS1	ENST00000264448	human	ensembl	74_37	+1	known	missense	c.11686	p.G3896S	0.127	NULL	NULL	-	no_errors	ALMS1	HGNC	ENSG00000116127	tier1	rs187887110	GMAF=0.0005	95	0	0.00	7	37	84.09
MUC4	0	genome.wustl.edu	37	3	195506473	195506473	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	3	195506473	195506473	A	G	SNP	MUC4	ENST00000463781	human	ensembl	74_37	-1	known	missense	c.11978	p.V3993A	0.000	NULL	pfam_Nidogen_extracell_dom,pfam_AMOP,pfam_VWF_type-D,smart_Nidogen_extracell_dom,smart_AMOP,smart_VWF_type-D,smart_EG-like_dom,pfscan_AMOP,pfscan_EG-like_dom	-	no_errors	MUC4	HGNC	ENSG00000145113	tier1	rs201922637	-	14	0	0.00	5	4	44.44
ADAMTS9	0	genome.wustl.edu	37	3	64502706	64502707	+	RNA	DEL	AC	AC	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	AC	AC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	3	64502706	64502707	AC	-	DEL	ADAMTS9	ENST00000467257	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	ADAMTS9	HGNC	ENSG00000163638	tier1			28	0	0.00	24	4	14.29
ADIRF-AS1	0	genome.wustl.edu	37	10	88728453	88728453	+	RNA	SNP	T	T	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	10	88728453	88728453	T	A	SNP	ADIRF-AS1	ENST00000609111	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ADIRF-AS1	HGNC	ENSG00000272734	tier1	-	-	13	0	0.00	1	7	87.50
BET1	0	genome.wustl.edu	37	7	93605345	93605345	+	Silent	SNP	A	A	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	93605345	93605345	A	T	SNP	BET1	ENST00000357520	human	ensembl	74_37	-1	known	silent	c.303	p.V101	0.007	NULL	pfam_T_SNARE_dom,pfscan_T_SNARE_dom	-	no_errors	BET1	HGNC	ENSG00000105829	tier1	-	-	61	0	0.00	38	15	28.30
HOOK1	0	genome.wustl.edu	37	1	60314110	60314110	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	60314110	60314110	G	C	SNP	HOOK1	ENST00000371208	human	ensembl	74_37	+1	known	missense	c.1053	p.M351I	1.000	pfam_Hook-related_fam	pfam_Hook-related_fam,superfamily_Prefoldin	-	no_errors	HOOK1	HGNC	ENSG00000134709	tier1	-	-	55	0	0.00	28	9	24.32
SLC27A5	0	genome.wustl.edu	37	19	59010563	59010563	+	Silent	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	19	59010563	59010563	C	T	SNP	SLC27A5	ENST00000263093	human	ensembl	74_37	-1	known	silent	c.1692	p.T564	0.197	pfam_AMP-dep_Synth/Lig	pfam_AMP-dep_Synth/Lig	-	no_errors	SLC27A5	HGNC	ENSG00000083807	tier1	-	-	64	0	0.00	37	4	9.76
NXPH3	0	genome.wustl.edu	37	17	47656469	47656469	+	Nonsense_Mutation	SNP	C	C	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	17	47656469	47656469	C	A	SNP	NXPH3	ENST00000328741	human	ensembl	74_37	+1	known	nonsense	c.566	p.S189*	0.997	pfam_NXPH/NXPE,pirsf_Neurexophilin	pfam_NXPH/NXPE,pirsf_Neurexophilin	-	no_errors	NXPH3	HGNC	ENSG00000182575	tier1	-	-	34	0	0.00	22	4	15.38
USP46	0	genome.wustl.edu	37	4	53497234	53497234	+	Frame_Shift_Del	DEL	G	G	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	4	53497234	53497234	G	-	DEL	USP46	ENST00000441222	human	ensembl	74_37	-1	known	frame_shift_del	c.114	p.N39fs	1.000	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	-	no_errors	USP46	HGNC	ENSG00000109189	tier1			38	0	0.00	9	2	18.18
CCT5	0	genome.wustl.edu	37	5	10261729	10261729	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	5	10261729	10261729	G	A	SNP	CCT5	ENST00000280326	human	ensembl	74_37	+1	known	missense	c.1051	p.E351K	0.999	pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,tigrfam_Chap_CCT_epsi	pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,prints_Chaperone_TCP-1,prints_Chaprnin_Cpn60,tigrfam_Chap_CCT_epsi	-	no_errors	CCT5	HGNC	ENSG00000150753	tier1	rs140095139	-	56	0	0.00	60	14	18.92
EPN3	0	genome.wustl.edu	37	17	48617655	48617655	+	Silent	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	17	48617655	48617655	G	A	SNP	EPN3	ENST00000537145	human	ensembl	74_37	+1	known	silent	c.1023	p.P341	0.952	NULL	pfam_Epsin_dom_N,superfamily_ENTH_VHS,smart_Epsin-like_N,pfscan_Epsin-like_N,pfscan_Ubiquitin-int_motif	-	no_errors	EPN3	HGNC	ENSG00000049283	tier1	-	-	44	0	0.00	18	6	25.00
TREML2	0	genome.wustl.edu	37	6	41168714	41168716	+	In_Frame_Del	DEL	CAG	CAG	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	CAG	CAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	6	41168714	41168716	CAG	-	DEL	TREML2	ENST00000483722	human	ensembl	74_37	-1	known	in_frame_del	c.33_31	p.L11in_frame_del	0.997:1.000:1.000	NULL	pfam_Ig_V-set,pfscan_Ig-like_dom	-	no_errors	TREML2	HGNC	ENSG00000112195	tier1			98	0	0.00	44	5	10.20
DEAF1	0	genome.wustl.edu	37	11	680002	680003	+	RNA	INS	-	-	ACCAGGATG			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	11	680002	680003	-	ACCAGGATG	INS	DEAF1	ENST00000525904	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	DEAF1	HGNC	ENSG00000177030	tier1			NA	NA	NA	NA	NA	NA
SSTR3	0	genome.wustl.edu	37	22	37603369	37603369	+	Silent	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	22	37603369	37603369	C	T	SNP	SSTR3	ENST00000328544	human	ensembl	74_37	-1	known	silent	c.474	p.P158	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfscan_GPCR_Rhodpsn_7TM,prints_Somatstn_rcpt_3,prints_GPCR_Rhodpsn,prints_Somatstn_rcpt,prints_Somatstn_rcpt_5,prints_Neuropept_B/W_rcpt	-	no_errors	SSTR3	HGNC	ENSG00000183473	tier1	-	-	18	0	0.00	7	12	63.16
MAGEC1	0	genome.wustl.edu	37	X	140996230	140996230	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	X	140996230	140996230	G	T	SNP	MAGEC1	ENST00000285879	human	ensembl	74_37	+1	known	missense	c.3040	p.A1014S	0.005	pfam_MAGE,pfscan_MAGE	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC1	HGNC	ENSG00000155495	tier1	-	-	57	0	0.00	34	4	10.26
NLGN1	0	genome.wustl.edu	37	3	173997210	173997210	+	Silent	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	3	173997210	173997210	G	A	SNP	NLGN1	ENST00000401917	human	ensembl	74_37	+1	known	silent	c.1539	p.A513	1.000	pfam_CarbesteraseB	pfam_CarbesteraseB,pfam_AB_hydrolase_3,prints_Neuroligin	-	no_errors	NLGN1	HGNC	ENSG00000169760	tier1	rs200258151	GMAF=0.0005	44	0	0.00	27	11	28.21
RRM2	0	genome.wustl.edu	37	2	10269400	10269400	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	10269400	10269400	A	G	SNP	RRM2	ENST00000360566	human	ensembl	74_37	+1	known	missense	c.1237	p.I413V	1.000	superfamily_Ferritin-like_SF	pfam_RNR_small,superfamily_Ferritin-like_SF	-	no_errors	RRM2	HGNC	ENSG00000171848	tier1	-	-	63	0	0.00	31	28	47.46
TSC1	0	genome.wustl.edu	37	9	135772703	135772703	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	9	135772703	135772703	T	C	SNP	TSC1	ENST00000298552	human	ensembl	74_37	-1	known	missense	c.2843	p.Y948C	1.000	NULL	pfam_Hamartin,superfamily_ARM-type_fold	-	no_errors	TSC1	HGNC	ENSG00000165699	tier1	-	-	69	0	0.00	14	29	67.44
ZNF790	0	genome.wustl.edu	37	19	37314268	37314268	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	19	37314268	37314268	G	C	SNP	ZNF790	ENST00000356725	human	ensembl	74_37	-1	known	missense	c.148	p.Q50E	0.277	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF790	HGNC	ENSG00000197863	tier1	-	-	44	0	0.00	12	16	57.14
ANKRD35	0	genome.wustl.edu	37	1	145558228	145558228	+	Silent	SNP	T	T	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	145558228	145558228	T	C	SNP	ANKRD35	ENST00000355594	human	ensembl	74_37	+1	known	silent	c.345	p.A115	0.998	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD35	HGNC	ENSG00000198483	tier1	-	-	35	0	0.00	16	3	15.79
MIR502	0	genome.wustl.edu	37	X	49779214	49779214	+	RNA	SNP	C	C	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	X	49779214	49779214	C	A	SNP	MIR502	ENST00000606349	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.550	-	-	-	no_errors	MIR502	HGNC	ENSG00000272080	tier1	-	-	56	0	0.00	30	4	11.76
KIAA2022	0	genome.wustl.edu	37	X	73961334	73961334	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	X	73961334	73961334	C	A	SNP	KIAA2022	ENST00000055682	human	ensembl	74_37	-1	known	missense	c.3058	p.D1020Y	1.000	NULL	NULL	-	no_errors	KIAA2022	HGNC	ENSG00000050030	tier1	-	-	37	0	0.00	14	3	17.65
ACSL3	0	genome.wustl.edu	37	2	223806326	223806326	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	223806326	223806326	A	G	SNP	ACSL3	ENST00000357430	human	ensembl	74_37	+1	known	missense	c.2117	p.K706R	1.000	NULL	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSL3	HGNC	ENSG00000123983	tier1	-	-	46	0	0.00	22	10	31.25
SLC4A10	0	genome.wustl.edu	37	2	162719573	162719573	+	Splice_Site	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	162719573	162719573	G	T	SNP	SLC4A10	ENST00000446997	human	ensembl	74_37	+1	known	splice_site	c.766+1	e6+1	1.000	-	-	-	no_errors	SLC4A10	HGNC	ENSG00000144290	tier1	-	-	61	0	0.00	20	19	48.72
MYH6	0	genome.wustl.edu	37	14	23862702	23862702	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	14	23862702	23862702	G	A	SNP	MYH6	ENST00000356287	human	ensembl	74_37	-1	known	missense	c.2954	p.A985V	1.000	NULL	pfam_Myosin_tail,pfam_Myosin_head_motor_dom,pfam_Myosin_N,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_Myosin_head_motor_dom,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH6	HGNC	ENSG00000197616	tier1	-	-	38	0	0.00	29	4	12.12
TUBGCP5	0	genome.wustl.edu	37	15	22851033	22851033	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	15	22851033	22851033	G	T	SNP	TUBGCP5	ENST00000283645	human	ensembl	74_37	+1	known	missense	c.1295	p.R432L	1.000	pfam_TUBGCP	pfam_TUBGCP	-	no_errors	TUBGCP5	HGNC	ENSG00000153575	tier1	-	-	47	0	0.00	23	7	23.33
KRT6C	0	genome.wustl.edu	37	12	52867394	52867394	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	12	52867394	52867394	C	T	SNP	KRT6C	ENST00000252250	human	ensembl	74_37	-1	known	missense	c.128	p.G43D	1.000	NULL	pfam_IF,superfamily_Prefoldin,prints_Keratin_II	-	no_errors	KRT6C	HGNC	ENSG00000170465	tier1	-	-	56	0	0.00	35	4	10.26
JUN	0	genome.wustl.edu	37	1	59248443	59248443	+	Silent	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	59248443	59248443	G	A	SNP	JUN	ENST00000371222	human	ensembl	74_37	-1	known	silent	c.300	p.P100	1.000	pfam_JNK	pfam_JNK,pfam_bZIP,superfamily_TF_DNA-bd,smart_bZIP,pfscan_bZIP,prints_Leuzip_Jun	-	no_errors	JUN	HGNC	ENSG00000177606	tier1	-	-	43	0	0.00	119	14	10.53
RASA1	0	genome.wustl.edu	37	5	86658444	86658444	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	5	86658444	86658444	C	T	SNP	RASA1	ENST00000274376	human	ensembl	74_37	+1	known	missense	c.1409	p.A470V	1.000	NULL	pfam_SH2,pfam_RasGAP,pfam_Pleckstrin_homology,pfam_SH3_domain,pfam_C2_dom,superfamily_Rho_GTPase_activation_prot,superfamily_C2_dom,smart_SH2,smart_SH3_domain,smart_Pleckstrin_homology,smart_C2_dom,smart_RasGAP,pfscan_C2_dom,pfscan_Pleckstrin_homology,pfscan_SH2,pfscan_SH3_domain,pfscan_RasGAP,prints_SH2	-	no_errors	RASA1	HGNC	ENSG00000145715	tier1	-	-	101	0	0.00	45	4	8.16
GNS	0	genome.wustl.edu	37	12	65115480	65115480	+	Nonsense_Mutation	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	12	65115480	65115480	G	T	SNP	GNS	ENST00000258145	human	ensembl	74_37	-1	known	nonsense	c.1314	p.C438*	0.920	pfam_Sulfatase,superfamily_Alkaline_phosphatase_core,pirsf_GlcNAc_6-SO4ase	pfam_Sulfatase,superfamily_Alkaline_phosphatase_core,pirsf_GlcNAc_6-SO4ase	-	no_errors	GNS	HGNC	ENSG00000135677	tier1	-	-	22	0	0.00	14	3	17.65
LGALS3BP	0	genome.wustl.edu	37	17	76967850	76967850	+	Silent	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	17	76967850	76967850	G	A	SNP	LGALS3BP	ENST00000262776	human	ensembl	74_37	-1	known	silent	c.1566	p.A522	0.981	NULL	pfam_SRCR,pfam_BACK,superfamily_Srcr_rcpt-rel,superfamily_BTB/POZ_fold,smart_Srcr_rcpt-rel,smart_BACK,pfscan_BTB/POZ-like,pfscan_SRCR,prints_SRCR	-	no_errors	LGALS3BP	HGNC	ENSG00000108679	tier1	-	-	59	0	0.00	34	12	26.09
ENSG00000228436	0	genome.wustl.edu	37	1	39341869	39341869	+	RNA	SNP	T	T	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	39341869	39341869	T	A	SNP	ENSG00000228436	ENST00000443161	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.058	-	-	-	no_errors	RP5-864K19.4	Clone_based_vega_gene	ENSG00000228436	tier1	-	-	60	0	0.00	27	16	37.21
CHRNA7	0	genome.wustl.edu	37	15	32460485	32460485	+	Silent	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	15	32460485	32460485	C	T	SNP	CHRNA7	ENST00000454250	human	ensembl	74_37	+1	known	silent	c.1422	p.N474	1.000	pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,prints_Nicotinic_acetylcholine_rcpt,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	CHRNA7	HGNC	ENSG00000175344	tier1	rs200301018	-	18	0	0.00	3	5	62.50
PRAMEF11	0	genome.wustl.edu	37	1	12887523	12887523	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	12887523	12887523	C	T	SNP	PRAMEF11	ENST00000535591	human	ensembl	74_37	-1	known	missense	c.334	p.E112K	0.020	NULL	NULL	-	no_errors	PRAMEF11	HGNC	ENSG00000204513	tier1	-	-	240	0	0.00	83	71	46.10
CLASP2	0	genome.wustl.edu	37	3	33602411	33602411	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	3	33602411	33602411	T	A	SNP	CLASP2	ENST00000399362	human	ensembl	74_37	-1	known	missense	c.2840	p.D947V	1.000	superfamily_ARM-type_fold	pfam_CLASP_N_dom,pfam_HEAT,superfamily_ARM-type_fold,pfscan_HEAT_type_2	-	no_errors	CLASP2	HGNC	ENSG00000163539	tier1	-	-	85	0	0.00	65	6	8.45
ABCA4	0	genome.wustl.edu	37	1	94463415	94463415	+	Splice_Site	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	94463415	94463415	G	T	SNP	ABCA4	ENST00000370225	human	ensembl	74_37	-1	known	splice_site	c.6729+2	e48+2	1.000	-	-	-	no_errors	ABCA4	HGNC	ENSG00000198691	tier1	-	-	40	0	0.00	14	5	26.32
SMARCC2	0	genome.wustl.edu	37	12	56583194	56583194	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	12	56583194	56583194	C	T	SNP	SMARCC2	ENST00000267064	human	ensembl	74_37	-1	known	missense	c.52	p.A18T	0.977	NULL	pfam_SWIRM,pfam_SANT/Myb,superfamily_Homeodomain-like,superfamily_BRCT_dom,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_SANT/Myb,pfscan_SWIRM,pfscan_Myb-like_dom	-	no_errors	SMARCC2	HGNC	ENSG00000139613	tier1	-	-	91	0	0.00	43	4	8.33
ABCG5	0	genome.wustl.edu	37	2	44041643	44041643	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	44041643	44041643	C	T	SNP	ABCG5	ENST00000260645	human	ensembl	74_37	-1	known	missense	c.1735	p.E579K	1.000	pfam_ABC_2_trans	pfam_ABC_2_trans,pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like	-	no_errors	ABCG5	HGNC	ENSG00000138075	tier1	-	-	149	0	0.00	130	41	23.98
BET1	0	genome.wustl.edu	37	7	93605346	93605346	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	93605346	93605346	A	T	SNP	BET1	ENST00000357520	human	ensembl	74_37	-1	known	missense	c.302	p.V101D	0.005	NULL	pfam_T_SNARE_dom,pfscan_T_SNARE_dom	-	no_errors	BET1	HGNC	ENSG00000105829	tier1	-	-	62	0	0.00	39	14	26.42
PTX4	0	genome.wustl.edu	37	16	1536545	1536545	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	16	1536545	1536545	C	T	SNP	PTX4	ENST00000447419	human	ensembl	74_37	-1	known	missense	c.832	p.A278T	0.013	pfam_Pentaxin,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin	pfam_Pentaxin,pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin,prints_Pentaxin	-	no_errors	PTX4	HGNC	ENSG00000251692	tier1	rs148493506	-	12	0	0.00	3	6	66.67
SEL1L2	0	genome.wustl.edu	37	20	13936777	13936777	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	20	13936777	13936777	G	A	SNP	SEL1L2	ENST00000284951	human	ensembl	74_37	-1	known	missense	c.59	p.T20I	0.440	NULL	pfam_Sel1-like,smart_Sel1-like	-	no_errors	SEL1L2	HGNC	ENSG00000101251	tier1	-	-	129	0	0.00	63	26	29.21
GPR158	0	genome.wustl.edu	37	10	25891039	25891039	+	RNA	DEL	A	A	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	10	25891039	25891039	A	-	DEL	GPR158	ENST00000490549	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.994	-	-	-	no_errors	GPR158	HGNC	ENSG00000151025	tier1			49	0	0.00	21	12	36.36
AHNAK	0	genome.wustl.edu	37	11	62288755	62288755	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	11	62288755	62288755	C	T	SNP	AHNAK	ENST00000378024	human	ensembl	74_37	-1	known	missense	c.13134	p.M4378I	1.000	NULL	superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	AHNAK	HGNC	ENSG00000124942	tier1	-	-	106	0	0.00	49	21	30.00
ENSG00000228532	0	genome.wustl.edu	37	X	114953402	114953402	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	X	114953402	114953402	G	A	SNP	ENSG00000228532	ENST00000449327	human	ensembl	74_37	-1	novel	nonsense	c.148	p.R50*	0.673	pfam_Rad60/SUMO_like,pfam_Ubiquitin_dom,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup	pfam_Rad60/SUMO_like,pfam_Ubiquitin_dom,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup	-	no_errors	RP1-241P17.4	Clone_based_vega_gene	ENSG00000228532	tier1	-	-	96	0	0.00	27	25	48.08
BET1	0	genome.wustl.edu	37	7	93605343	93605343	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	93605343	93605343	G	A	SNP	BET1	ENST00000357520	human	ensembl	74_37	-1	known	missense	c.305	p.P102L	0.017	NULL	pfam_T_SNARE_dom,pfscan_T_SNARE_dom	-	no_errors	BET1	HGNC	ENSG00000105829	tier1	-	-	62	0	0.00	39	16	29.09
OR5H14	0	genome.wustl.edu	37	3	97868430	97868430	+	Silent	SNP	T	T	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	3	97868430	97868430	T	A	SNP	OR5H14	ENST00000437310	human	ensembl	74_37	+1	known	silent	c.201	p.A67	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5H14	HGNC	ENSG00000236032	tier1	-	-	95	0	0.00	26	20	43.48
TRPC5	0	genome.wustl.edu	37	X	111090651	111090651	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	X	111090651	111090651	C	T	SNP	TRPC5	ENST00000262839	human	ensembl	74_37	-1	known	missense	c.1391	p.R464H	1.000	pfam_Ion_trans_dom,tigrfam_TRP_channel	pfam_Ion_trans_dom,pfam_TRP_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,prints_TRPC5_channel,prints_TRPC_channel,tigrfam_TRP_channel	-	no_errors	TRPC5	HGNC	ENSG00000072315	tier1	-	-	38	0	0.00	18	13	41.94
ZNF335	0	genome.wustl.edu	37	20	44578874	44578876	+	In_Frame_Del	DEL	TGT	TGT	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	TGT	TGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	20	44578874	44578876	TGT	-	DEL	ZNF335	ENST00000322927	human	ensembl	74_37	-1	known	in_frame_del	c.3471_3469	p.T1157in_frame_del	0.141:0.993:0.993	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF335	HGNC	ENSG00000198026	tier1			35	0	0.00	30	5	14.29
ZNF76	0	genome.wustl.edu	37	6	35262984	35262984	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	6	35262984	35262984	G	A	SNP	ZNF76	ENST00000373953	human	ensembl	74_37	+1	known	missense	c.1672	p.A558T	0.953	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF76	HGNC	ENSG00000065029	tier1	-	-	48	0	0.00	41	4	8.89
COL19A1	0	genome.wustl.edu	37	6	70909399	70909399	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	6	70909399	70909399	A	C	SNP	COL19A1	ENST00000322773	human	ensembl	74_37	+1	known	missense	c.3182	p.K1061T	1.000	NULL	pfam_Collagen,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G	-	no_errors	COL19A1	HGNC	ENSG00000082293	tier1	-	-	86	0	0.00	48	5	9.43
PARP6	0	genome.wustl.edu	37	15	72541646	72541646	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	15	72541646	72541646	C	T	SNP	PARP6	ENST00000287196	human	ensembl	74_37	-1	known	missense	c.1501	p.A501T	1.000	pfam_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_cat_dom	pfam_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_cat_dom	-	no_errors	PARP6	HGNC	ENSG00000137817	tier1	-	-	53	0	0.00	29	4	12.12
SDK2	0	genome.wustl.edu	37	17	71382003	71382003	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	17	71382003	71382003	C	A	SNP	SDK2	ENST00000392650	human	ensembl	74_37	-1	known	missense	c.4552	p.V1518L	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	SDK2	HGNC	ENSG00000069188	tier1	-	-	26	0	0.00	24	15	38.46
PCDH20	0	genome.wustl.edu	37	13	61987993	61987994	+	Frame_Shift_Ins	INS	-	-	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	13	61987993	61987994	-	C	INS	PCDH20	ENST00000409186	human	ensembl	74_37	-1	known	frame_shift_ins	c.239_238	p.V80fs	1.000:0.994	pfscan_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH20	HGNC	ENSG00000197991	tier1			18	0	0.00	8	3	27.27
DAPP1	0	genome.wustl.edu	37	4	100756843	100756843	+	Silent	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	4	100756843	100756843	C	T	SNP	DAPP1	ENST00000512369	human	ensembl	74_37	+1	known	silent	c.165	p.D55	0.976	pfam_SH2,smart_SH2,pfscan_SH2,prints_SH2	pfam_SH2,pfam_Pleckstrin_homology,smart_SH2,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_SH2,prints_SH2	-	no_errors	DAPP1	HGNC	ENSG00000070190	tier1	-	-	41	0	0.00	12	10	45.45
MAP2K4	0	genome.wustl.edu	37	17	12013743	12013743	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	17	12013743	12013743	G	A	SNP	MAP2K4	ENST00000415385	human	ensembl	74_37	+1	known	missense	c.718	p.D240N	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAP2K4	HGNC	ENSG00000065559	tier1	-	-	148	0	0.00	40	19	32.20
SLC13A4	0	genome.wustl.edu	37	7	135366355	135366355	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	135366355	135366355	A	G	SNP	SLC13A4	ENST00000354042	human	ensembl	74_37	-1	known	missense	c.1837	p.Y613H	1.000	NULL	pfam_Na/sul_symport,pfam_Cit_transptr-like_dom,pfam_DctM	-	no_errors	SLC13A4	HGNC	ENSG00000164707	tier1	-	-	66	0	0.00	146	18	10.98
ENSG00000259607	0	genome.wustl.edu	37	8	28924925	28924925	+	RNA	DEL	A	A	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	8	28924925	28924925	A	-	DEL	ENSG00000259607	ENST00000560714	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.899	-	-	-	no_errors	CTD-2647L4.5	Clone_based_vega_gene	ENSG00000259607	tier1			45	0	0.00	11	2	15.38
MYBPC1	0	genome.wustl.edu	37	12	102008351	102008351	+	RNA	SNP	A	A	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	12	102008351	102008351	A	G	SNP	MYBPC1	ENST00000550501	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	MYBPC1	HGNC	ENSG00000196091	tier1	-	-	62	0	0.00	32	6	15.79
ENSG00000260628	0	genome.wustl.edu	37	16	31993452	31993452	+	RNA	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	16	31993452	31993452	G	T	SNP	ENSG00000260628	ENST00000568570	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-1166P10.1	Clone_based_vega_gene	ENSG00000260628	tier1	-	-	66	0	0.00	33	9	20.93
AEBP2	0	genome.wustl.edu	37	12	19667686	19667686	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	12	19667686	19667686	T	A	SNP	AEBP2	ENST00000398864	human	ensembl	74_37	+1	known	missense	c.1449	p.D483E	1.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	AEBP2	HGNC	ENSG00000139154	tier1	-	-	72	0	0.00	13	15	53.57
PHKA1	0	genome.wustl.edu	37	X	71932722	71932722	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	X	71932722	71932722	C	G	SNP	PHKA1	ENST00000373539	human	ensembl	74_37	-1	known	missense	c.136	p.D46H	1.000	pfam_Glyco_hydro_15,superfamily_6-hairpin_glycosidase-like	pfam_Glyco_hydro_15,superfamily_6-hairpin_glycosidase-like	-	no_errors	PHKA1	HGNC	ENSG00000067177	tier1	-	-	53	0	0.00	22	7	24.14
TBC1D22B	0	genome.wustl.edu	37	6	37247153	37247153	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	6	37247153	37247153	G	T	SNP	TBC1D22B	ENST00000373491	human	ensembl	74_37	+1	known	missense	c.187	p.A63S	1.000	NULL	pfam_Rab-GTPase-TBC_dom,superfamily_Rab-GTPase-TBC_dom,smart_Rab-GTPase-TBC_dom,pfscan_Rab-GTPase-TBC_dom	-	no_errors	TBC1D22B	HGNC	ENSG00000065491	tier1	-	-	62	0	0.00	39	11	22.00
SLC9A8	0	genome.wustl.edu	37	20	48467301	48467301	+	Frame_Shift_Del	DEL	T	T	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	20	48467301	48467301	T	-	DEL	SLC9A8	ENST00000417961	human	ensembl	74_37	+1	known	frame_shift_del	c.537	p.F182fs	0.189	pfam_Cation/H_exchanger,tigrfam_NaH_exchanger	pfam_Cation/H_exchanger,prints_NaH_exchanger,tigrfam_NaH_exchanger	-	no_errors	SLC9A8	HGNC	ENSG00000197818	tier1			19	0	0.00	15	6	28.57
PCLO	0	genome.wustl.edu	37	7	82582943	82582944	+	Frame_Shift_Ins	INS	-	-	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	82582943	82582944	-	T	INS	PCLO	ENST00000333891	human	ensembl	74_37	-1	known	frame_shift_ins	c.7326_7325	p.L2443fs	0.096:0.984	NULL	pfam_Znf_piccolo,pfam_C2_dom,pfam_PDZ,superfamily_C2_dom,superfamily_PDZ,superfamily_Znf_FYVE_PHD,smart_PDZ,smart_C2_dom,pfscan_C2_dom,pfscan_PDZ	-	no_errors	PCLO	HGNC	ENSG00000186472	tier1			44	0	0.00	15	3	16.67
TMEM132A	0	genome.wustl.edu	37	11	60704165	60704165	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	11	60704165	60704165	G	A	SNP	TMEM132A	ENST00000005286	human	ensembl	74_37	+1	known	missense	c.2861	p.R954Q	0.905	NULL	NULL	-	no_errors	TMEM132A	HGNC	ENSG00000006118	tier1	-	-	41	0	0.00	22	6	21.43
KNDC1	0	genome.wustl.edu	37	10	134980985	134980985	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	10	134980985	134980985	G	C	SNP	KNDC1	ENST00000368572	human	ensembl	74_37	+1	known	missense	c.203	p.S68T	1.000	smart_KIND	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,superfamily_Kinase-like_dom,smart_KIND,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	KNDC1	HGNC	ENSG00000171798	tier1	-	-	56	0	0.00	21	15	41.67
NAT1	0	genome.wustl.edu	37	8	18080367	18080367	+	Frame_Shift_Del	DEL	T	T	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	8	18080367	18080367	T	-	DEL	NAT1	ENST00000545197	human	ensembl	74_37	+1	known	frame_shift_del	c.997	p.F333fs	0.982	pfam_Arylamine_N-AcTrfase,prints_Arylamine_N-AcTrfase	pfam_Arylamine_N-AcTrfase,prints_Arylamine_N-AcTrfase	-	no_errors	NAT1	HGNC	ENSG00000171428	tier1			76	0	0.00	16	2	11.11
SYPL2	0	genome.wustl.edu	37	1	110019410	110019410	+	Silent	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	110019410	110019410	C	T	SNP	SYPL2	ENST00000369872	human	ensembl	74_37	+1	known	silent	c.267	p.I89	0.927	pfam_Marvel	pfam_Marvel,prints_Synaptophysin/porin	-	no_errors	SYPL2	HGNC	ENSG00000143028	tier1	-	-	18	0	0.00	23	10	30.30
GPR55	0	genome.wustl.edu	37	2	231775273	231775273	+	Silent	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	231775273	231775273	G	T	SNP	GPR55	ENST00000392039	human	ensembl	74_37	-1	known	silent	c.405	p.P135	0.948	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	GPR55	HGNC	ENSG00000135898	tier1	-	-	47	0	0.00	39	4	9.30
MYO3A	0	genome.wustl.edu	37	10	26463350	26463350	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	10	26463350	26463350	T	C	SNP	MYO3A	ENST00000265944	human	ensembl	74_37	+1	known	missense	c.4157	p.V1386A	0.063	NULL	pfam_Myosin_head_motor_dom,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,pfscan_Prot_kinase_dom,prints_Myosin_head_motor_dom	-	no_errors	MYO3A	HGNC	ENSG00000095777	tier1	-	-	60	0	0.00	40	13	24.53
ENSG00000229743	0	genome.wustl.edu	37	2	105484676	105484676	+	RNA	SNP	C	C	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	2	105484676	105484676	C	G	SNP	ENSG00000229743	ENST00000433433	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	AC018730.3	Clone_based_vega_gene	ENSG00000229743	tier1	-	-	50	0	0.00	14	17	54.84
MLLT4	0	genome.wustl.edu	37	6	168366692	168366694	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	GAG	GAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	6	168366692	168366694	GAG	-	DEL	MLLT4	ENST00000366806	human	ensembl	74_37	+1	known	in_frame_del	c.5203_5205	p.E1738in_frame_del	1.000:1.000:1.000	NULL	pfam_Ras-assoc,pfam_Dil_domain,pfam_PDZ,pfam_FHA_dom,superfamily_PDZ,superfamily_SMAD_FHA_domain,smart_Ras-assoc,smart_FHA_dom,smart_PDZ,pfscan_Dilute,pfscan_PDZ,pfscan_Ras-assoc	-	no_errors	MLLT4	HGNC	ENSG00000130396	tier1			47	0	0.00	23	5	17.86
MET	0	genome.wustl.edu	37	7	116339237	116339237	+	Silent	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	116339237	116339237	C	T	SNP	MET	ENST00000318493	human	ensembl	74_37	+1	known	silent	c.99	p.S33	0.005	pirsf_Tyr_kinase_HGF/MSP_rcpt,pfscan_Semap_dom	pirsf_Tyr_kinase_HGF/MSP_rcpt,pfam_Semap_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Kinase-like_dom,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Semap_dom,pfscan_Prot_kinase_dom	-	no_errors	MET	HGNC	ENSG00000105976	tier1	-	-	70	0	0.00	33	38	53.52
PTTG1IP	0	genome.wustl.edu	37	21	46276273	46276276	+	Frame_Shift_Del	DEL	AAGT	AAGT	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	AAGT	AAGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	21	46276273	46276276	AAGT	-	DEL	PTTG1IP	ENST00000330938	human	ensembl	74_37	-1	known	frame_shift_del	c.284_281	p.N94fs	0.995:1.000:1.000:1.000	NULL	smart_Plexin-like_fold	-	no_errors	PTTG1IP	HGNC	ENSG00000183255	tier1			45	0	0.00	20	3	13.04
WWC1	0	genome.wustl.edu	37	5	167894900	167894900	+	Frame_Shift_Del	DEL	C	C	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	5	167894900	167894900	C	-	DEL	WWC1	ENST00000265293	human	ensembl	74_37	+1	known	frame_shift_del	c.3206	p.A1069fs	0.970	NULL	pfam_WW_dom,superfamily_C2_dom,superfamily_WW_dom,smart_WW_dom,pfscan_WW_dom	-	no_errors	WWC1	HGNC	ENSG00000113645	tier1			49	0	0.00	12	2	14.29
BET1	0	genome.wustl.edu	37	7	93605300	93605300	+	Silent	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	93605300	93605300	G	A	SNP	BET1	ENST00000357520	human	ensembl	74_37	-1	known	silent	c.348	p.F116	0.136	NULL	pfam_T_SNARE_dom,pfscan_T_SNARE_dom	-	no_errors	BET1	HGNC	ENSG00000105829	tier1	-	-	59	0	0.00	34	31	47.69
ENSG00000260973	0	genome.wustl.edu	37	16	22623130	22623130	+	RNA	SNP	G	G	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	16	22623130	22623130	G	A	SNP	ENSG00000260973	ENST00000567401	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.395	-	-	-	no_errors	RP11-105C19.2	Clone_based_vega_gene	ENSG00000260973	tier1	-	-	49	0	0.00	34	7	17.07
IGFN1	0	genome.wustl.edu	37	1	201181230	201181230	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	1	201181230	201181230	G	T	SNP	IGFN1	ENST00000335211	human	ensembl	74_37	+1	known	missense	c.7209	p.K2403N	0.000	NULL	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	IGFN1	HGNC	ENSG00000163395	tier1	-	-	28	0	0.00	6	12	66.67
RASGRP2	0	genome.wustl.edu	37	11	64508388	64508388	+	Frame_Shift_Del	DEL	C	C	-			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	11	64508388	64508388	C	-	DEL	RASGRP2	ENST00000377486	human	ensembl	74_37	-1	putative	frame_shift_del	c.403	p.A135fs	0.001	NULL	pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,smart_Ras-like_Gua-exchang_fac_N,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	RASGRP2	HGNC	ENSG00000068831	tier1			24	0	0.00	24	3	11.11
OPN1SW	0	genome.wustl.edu	37	7	128415802	128415802	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	7	128415802	128415802	T	G	SNP	OPN1SW	ENST00000249389	human	ensembl	74_37	-1	known	missense	c.43	p.I15L	0.972	prints_Opsin_blue	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_serpentine_rcpt_Srw,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfscan_GPCR_Rhodpsn_7TM,prints_Opsin_blue,prints_GPCR_Rhodpsn,prints_Opsin	-	no_errors	OPN1SW	HGNC	ENSG00000128617	tier1	rs200504235	GMAF=0.0005	59	0	0.00	80	28	25.93
PCDH7	0	genome.wustl.edu	37	4	30723421	30723421	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	4	30723421	30723421	T	A	SNP	PCDH7	ENST00000543491	human	ensembl	74_37	+1	known	missense	c.377	p.L126Q	1.000	smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Protocadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH7	HGNC	ENSG00000169851	tier1	-	-	61	0	0.00	5	10	66.67
NOMO2	0	genome.wustl.edu	37	16	18554998	18554998	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	16	18554998	18554998	C	G	SNP	NOMO2	ENST00000381474	human	ensembl	74_37	-1	known	missense	c.676	p.D226H	1.000	superfamily_CarboxyPept-like_regulatory	pfam_DUF2012,superfamily_Carb-bd-like_fold,superfamily_CarboxyPept-like_regulatory,superfamily_Collagen-bd_Cna_B-typ_dom	-	no_errors	NOMO2	HGNC	ENSG00000185164	tier1	-	-	156	0	0.00	133	18	11.92
GRAP2	0	genome.wustl.edu	37	22	40351885	40351885	+	Silent	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	22	40351885	40351885	C	T	SNP	GRAP2	ENST00000344138	human	ensembl	74_37	+1	known	silent	c.141	p.P47	1.000	pfam_SH3_domain,pfam_SH3_2,smart_SH3_domain,pfscan_SH3_domain	pfam_SH3_domain,pfam_SH2,pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain,smart_SH2,pfscan_SH2,pfscan_SH3_domain,prints_SH2,prints_SH3_domain	-	no_errors	GRAP2	HGNC	ENSG00000100351	tier1	-	-	62	0	0.00	18	40	68.97
SALL1	0	genome.wustl.edu	37	16	51175081	51175081	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	16	51175081	51175081	G	T	SNP	SALL1	ENST00000251020	human	ensembl	74_37	-1	known	missense	c.1052	p.P351Q	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	SALL1	HGNC	ENSG00000103449	tier1	-	-	30	0	0.00	35	6	14.63
PKD1L2	0	genome.wustl.edu	37	16	81208264	81208264	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A7EF-01A-11D-A33E-09	TCGA-DX-A7EF-10A-01D-A33H-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a1c5c19d-3879-4216-ab2b-b4ab3be9ca98	c66e0b91-0c95-4208-90c7-39a8f030fff1	16	81208264	81208264	C	T	SNP	PKD1L2	ENST00000527937	human	ensembl	74_37	-1	known	missense	c.607	p.V203M	0.000	pfscan_REJ-like	superfamily_Coatomer/clathrin_app_Ig-like,pfscan_REJ-like	-	no_errors	PKD1L2	HGNC	ENSG00000166473	tier1	-	-	53	0	0.00	29	13	30.95
