Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
TTBK2	0	genome.wustl.edu	37	15	43045133	43045133	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	15	43045133	43045133	C	G	SNP	TTBK2	ENST00000267890	human	ensembl	74_37	-1	known	missense	c.2311	p.E771Q	0.997	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	TTBK2	HGNC	ENSG00000128881	tier1	-	-	62	0	0.00	42	31	42.47
DNAH17	0	genome.wustl.edu	37	17	76446859	76446859	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	17	76446859	76446859	G	A	SNP	DNAH17	ENST00000389840	human	ensembl	74_37	-1	known	missense	c.10762	p.R3588C	1.000	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_HR1_rho-bd	-	no_errors	DNAH17	HGNC	ENSG00000187775	tier1	-	-	62	0	0.00	27	24	47.06
TTBK2	0	genome.wustl.edu	37	15	43044957	43044957	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	15	43044957	43044957	C	T	SNP	TTBK2	ENST00000267890	human	ensembl	74_37	-1	known	silent	c.2487	p.Q829	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	TTBK2	HGNC	ENSG00000128881	tier1	-	-	46	0	0.00	25	29	53.70
TRAK1	0	genome.wustl.edu	37	3	42251577	42251578	+	In_Frame_Ins	INS	-	-	GGA			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	3	42251577	42251578	-	GGA	INS	TRAK1	ENST00000341421	human	ensembl	74_37	+1	known	in_frame_ins	c.1889_1890	p.634in_frame_insE	0.010:0.044	NULL	pfam_HAP1_N,pfam_Traffickng_kinesin-bd_prot_dom	-	no_errors	TRAK1	HGNC	ENSG00000182606	tier1			23	0	0.00	28	6	17.65
MSH3	0	genome.wustl.edu	37	5	79950712	79950738	+	In_Frame_Del	DEL	GCGGCCGCAGCGGCCGCAGCGCCCCCA	GCGGCCGCAGCGGCCGCAGCGCCCCCA	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	GCGGCCGCAGCGGCCGCAGCGCCCCCA	GCGGCCGCAGCGGCCGCAGCGCCCCCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	5	79950712	79950738	GCGGCCGCAGCGGCCGCAGCGCCCCCA	-	DEL	MSH3	ENST00000265081	human	ensembl	74_37	+1	known	in_frame_del	c.166_192	p.AAAAAAPPA57in_frame_del	0.238:0.205:0.172:0.140:0.107:0.075:0.032:0.035:0.048:0.057:0.087:0.730:0.747:0.894:0.911:0.915:0.941:0.965:0.997:1.000:1.000:1.000:1.000:0.988:0.984:0.963:0.965	NULL	pfam_DNA_mismatch_repair_MutS_C,pfam_DNA_mismatch_repair_MutS_core,pfam_DNA_mmatch_repair_MutS_con_dom,pfam_DNA_mismatch_repair_MutS-lik_N,pfam_DNA_mismatch_repair_MutS_clamp,superfamily_DNA_mismatch_repair_MutS_core,superfamily_P-loop_NTPase,superfamily_DNA_mismatch_repair_MutS_N,superfamily_DNA_mmatch_repair_MutS_con_dom,smart_DNA_mismatch_repair_MutS_core,smart_DNA_mismatch_repair_MutS_C	-	no_errors	MSH3	HGNC	ENSG00000113318	tier1			NA	NA	NA	NA	NA	NA
LIPM	0	genome.wustl.edu	37	10	90572870	90572870	+	Silent	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	90572870	90572870	G	T	SNP	LIPM	ENST00000404743	human	ensembl	74_37	+1	known	silent	c.282	p.V94	0.895	pfam_AB_hydrolase_lipase	pfam_AB_hydrolase_lipase,pfam_AB_hydrolase_1	-	no_errors	LIPM	HGNC	ENSG00000173239	tier1	-	-	38	0	0.00	23	4	14.81
MIR137HG	0	genome.wustl.edu	37	1	98511783	98511783	+	RNA	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	98511783	98511783	C	T	SNP	MIR137HG	ENST00000424528	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.909	-	-	-	no_errors	MIR137HG	HGNC	ENSG00000225206	tier1	-	-	31	0	0.00	9	9	50.00
MUC2	0	genome.wustl.edu	37	11	1098687	1098687	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	1098687	1098687	G	A	SNP	MUC2	ENST00000441003	human	ensembl	74_37	+1	known	missense	c.7057	p.D2353N	0.118	pfam_Unchr_dom_Cys-rich,smart_Unchr_dom_Cys-rich	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,superfamily_Prot_inh_PMP,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC2	HGNC	ENSG00000198788	tier1	-	-	112	0	0.00	10	54	84.38
ELFN2	0	genome.wustl.edu	37	22	37770666	37770666	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	22	37770666	37770666	G	A	SNP	ELFN2	ENST00000402918	human	ensembl	74_37	-1	known	silent	c.909	p.H303	0.337	superfamily_Fibronectin_type3	superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,pfscan_LPXTG_anchor	-	no_errors	ELFN2	HGNC	ENSG00000166897	tier1	rs201226596	-	94	0	0.00	14	45	76.27
ARHGEF11	0	genome.wustl.edu	37	1	156950243	156950243	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	156950243	156950243	C	T	SNP	ARHGEF11	ENST00000368194	human	ensembl	74_37	-1	known	missense	c.259	p.D87N	0.988	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	pfam_RGS-like_dom,pfam_DH-domain,pfam_PDZ,pfam_RGS_dom,superfamily_DH-domain,superfamily_Regulat_G_prot_signal_superfam,superfamily_PDZ,smart_PDZ,smart_Regulat_G_prot_signal_superfam,smart_DH-domain,smart_Pleckstrin_homology,pfscan_PDZ,pfscan_Pleckstrin_homology,pfscan_Regulat_G_prot_signal_superfam,pfscan_DH-domain	-	no_errors	ARHGEF11	HGNC	ENSG00000132694	tier1	-	-	100	0	0.00	120	13	9.77
HSPA8	0	genome.wustl.edu	37	11	122930678	122930678	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	122930678	122930678	G	A	SNP	HSPA8	ENST00000534624	human	ensembl	74_37	-1	known	missense	c.623	p.S208L	1.000	pfam_Hsp_70_fam,pfam_MreB_Mrl,prints_Hsp_70_fam	pfam_Hsp_70_fam,pfam_MreB_Mrl,prints_Hsp_70_fam	-	no_errors	HSPA8	HGNC	ENSG00000109971	tier1	-	-	23	0	0.00	20	4	16.67
E2F5	0	genome.wustl.edu	37	8	86089854	86089854	+	Missense_Mutation	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	86089854	86089854	C	A	SNP	E2F5	ENST00000256117	human	ensembl	74_37	+1	known	missense	c.199	p.Q67K	1.000	pfam_E2F_TDP	pfam_E2F_TDP	-	no_errors	E2F5	HGNC	ENSG00000133740	tier1	-	-	30	0	0.00	13	3	18.75
MALAT1	0	genome.wustl.edu	37	11	65268480	65268480	+	RNA	DEL	T	T	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	65268480	65268480	T	-	DEL	MALAT1	ENST00000534336	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MALAT1	HGNC	ENSG00000251562	tier1			29	0	0.00	26	3	10.34
WDHD1	0	genome.wustl.edu	37	14	55493472	55493472	+	Missense_Mutation	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	14	55493472	55493472	G	T	SNP	WDHD1	ENST00000360586	human	ensembl	74_37	-1	known	missense	c.34	p.H12N	1.000	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,pfam_DUF3639,pfam_TIF_beta_prop-like,superfamily_WD40_repeat_dom,superfamily_HMG_box_dom,smart_WD40_repeat,smart_HMG_box_dom,pfscan_HMG_box_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDHD1	HGNC	ENSG00000198554	tier1	-	-	77	0	0.00	39	4	9.30
WDFY4	0	genome.wustl.edu	37	10	49951200	49951200	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951200	49951200	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	missense	c.2066	p.S689F	0.991	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	63	0	0.00	88	14	13.73
EMP2	0	genome.wustl.edu	37	16	10625606	10625613	+	RNA	DEL	ATGAATGA	ATGAATGA	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	ATGAATGA	ATGAATGA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	10625606	10625613	ATGAATGA	-	DEL	EMP2	ENST00000566033	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.092:0.092:0.091:0.090:0.088:0.085:0.082:0.078	-	-	-	no_errors	EMP2	HGNC	ENSG00000213853	tier1			NA	NA	NA	NA	NA	NA
PAPD5	0	genome.wustl.edu	37	16	50263693	50263693	+	RNA	DEL	T	T	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	50263693	50263693	T	-	DEL	PAPD5	ENST00000573002	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.737	-	-	-	no_errors	PAPD5	HGNC	ENSG00000121274	tier1			34	0	0.00	14	3	17.65
MYL6	0	genome.wustl.edu	37	12	56557112	56557112	+	RNA	DEL	T	T	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	56557112	56557112	T	-	DEL	MYL6	ENST00000551954	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.826	-	-	-	no_errors	MYL6	HGNC	ENSG00000092841	tier1			13	0	0.00	14	3	17.65
CUX1	0	genome.wustl.edu	37	7	101801856	101801856	+	Missense_Mutation	SNP	A	A	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	7	101801856	101801856	A	T	SNP	CUX1	ENST00000360264	human	ensembl	74_37	+1	known	missense	c.724	p.M242L	1.000	NULL	pfam_Hmoeo_CUT,pfam_Homeobox_dom,superfamily_Lambda_DNA-bd_dom,superfamily_Homeodomain-like,superfamily_LemA-like_dom,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Hmoeo_CUT	-	no_errors	CUX1	HGNC	ENSG00000257923	tier1	-	-	57	0	0.00	24	24	50.00
LOC440157	0	genome.wustl.edu	37	14	19686757	19686757	+	RNA	SNP	A	A	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	14	19686757	19686757	A	G	SNP	LOC440157	ENST00000418499	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.130	-	-	-	no_errors	AL589743.1	Clone_based_vega_gene	ENSG00000225210	tier1	-	-	18	0	0.00	8	7	46.67
ASTN1	0	genome.wustl.edu	37	1	177001821	177001821	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	177001821	177001821	G	A	SNP	ASTN1	ENST00000367654	human	ensembl	74_37	-1	known	silent	c.636	p.H212	0.099	NULL	superfamily_Fibronectin_type3,smart_EG-like_dom,smart_MACPF,pfscan_Fibronectin_type3	-	no_errors	ASTN1	HGNC	ENSG00000152092	tier1	-	-	52	0	0.00	45	22	32.84
ANGPTL3	0	genome.wustl.edu	37	1	63070097	63070097	+	RNA	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	63070097	63070097	C	T	SNP	ANGPTL3	ENST00000493994	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000	-	-	-	no_errors	ANGPTL3	HGNC	ENSG00000132855	tier1	-	-	14	0	0.00	5	4	44.44
LOR	0	genome.wustl.edu	37	1	153233991	153233992	+	In_Frame_Ins	INS	-	-	CTCTGGCGGCGG			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	153233991	153233992	-	CTCTGGCGGCGG	INS	LOR	ENST00000368742	human	ensembl	74_37	+1	known	in_frame_ins	c.566_567	p.193in_frame_insGSGG	0.014:0.200	NULL	NULL	-	no_errors	LOR	HGNC	ENSG00000203782	tier1			NA	NA	NA	NA	NA	NA
NUMBL	0	genome.wustl.edu	37	19	41173893	41173898	+	In_Frame_Del	DEL	TGCTGT	TGCTGT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TGCTGT	TGCTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	19	41173893	41173898	TGCTGT	-	DEL	NUMBL	ENST00000252891	human	ensembl	74_37	-1	known	in_frame_del	c.1310_1305	p.QQ439in_frame_del	1.000:1.000:1.000:1.000:1.000:0.998	pirsf_Numb/numb-like	pfam_Numb_domain,pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pirsf_Numb/numb-like,pfscan_PTB/PI_dom	-	no_errors	NUMBL	HGNC	ENSG00000105245	tier1			NA	NA	NA	NA	NA	NA
HSPBP1	0	genome.wustl.edu	37	19	55790886	55790887	+	In_Frame_Ins	INS	-	-	GCCGCCGCC			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	19	55790886	55790887	-	GCCGCCGCC	INS	HSPBP1	ENST00000255631	human	ensembl	74_37	-1	known	in_frame_ins	c.91_90	p.30in_frame_insGGG	0.883:0.989	NULL	superfamily_ARM-type_fold	-	no_errors	HSPBP1	HGNC	ENSG00000133265	tier1			NA	NA	NA	NA	NA	NA
HNF1B	0	genome.wustl.edu	37	17	36091772	36091772	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	17	36091772	36091772	C	G	SNP	HNF1B	ENST00000225893	human	ensembl	74_37	-1	known	missense	c.859	p.G287R	1.000	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	pfam_HNF1b_C,pfam_HNF-1_N,pfam_Homeobox_dom,superfamily_Lambda_DNA-bd_dom,superfamily_Homeodomain-like,superfamily_HNF1_dimer_dom,smart_Homeobox_dom,pfscan_Homeobox_dom	-	no_errors	HNF1B	HGNC	ENSG00000108753	tier1	-	-	34	0	0.00	15	20	57.14
ENSG00000183292	0	genome.wustl.edu	37	2	131334335	131334335	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	2	131334335	131334335	C	T	SNP	ENSG00000183292	ENST00000409982	human	ensembl	74_37	+1	putative	missense	c.289	p.P97S	0.000	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	-	no_errors	AC140481.2	Clone_based_vega_gene	ENSG00000183292	tier1	-	-	10	0	0.00	10	6	37.50
ADAM28	0	genome.wustl.edu	37	8	24168921	24168921	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	24168921	24168921	C	T	SNP	ADAM28	ENST00000265769	human	ensembl	74_37	+1	known	silent	c.354	p.D118	0.730	pfam_Peptidase_M12B_N	pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_ADAM_Cys-rich,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_EG-like_dom,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	-	no_errors	ADAM28	HGNC	ENSG00000042980	tier1	rs144018592	-	64	0	0.00	61	22	26.51
ENSG00000242474	0	genome.wustl.edu	37	7	149458	149459	+	RNA	INS	-	-	CTCCT			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	7	149458	149459	-	CTCCT	INS	ENSG00000242474	ENST00000497320	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002:0.001	-	-	-	no_errors	AC093627.9	Clone_based_vega_gene	ENSG00000242474	tier1			NA	NA	NA	NA	NA	NA
FAM151A	0	genome.wustl.edu	37	1	55081801	55081801	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	55081801	55081801	C	T	SNP	FAM151A	ENST00000302250	human	ensembl	74_37	-1	known	missense	c.307	p.G103S	0.000	pfam_DUF2181	pfam_DUF2181	-	no_errors	FAM151A	HGNC	ENSG00000162391	tier1	rs202087836	GMAF=0.0005	41	0	0.00	39	4	9.30
DZANK1	0	genome.wustl.edu	37	20	18446050	18446051	+	RNA	INS	-	-	TGTGCACTTATAGC			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	20	18446050	18446051	-	TGTGCACTTATAGC	INS	DZANK1	ENST00000460891	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.050:0.000	-	-	-	no_errors	DZANK1	HGNC	ENSG00000089091	tier1			NA	NA	NA	NA	NA	NA
FOXA2	0	genome.wustl.edu	37	20	22562842	22562842	+	Silent	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	20	22562842	22562842	C	G	SNP	FOXA2	ENST00000419308	human	ensembl	74_37	-1	known	silent	c.1038	p.G346	0.997	NULL	pfam_TF_fork_head,pfam_Fork-head_N,pfam_Forkhead_box_C,smart_TF_fork_head,pfscan_TF_fork_head,prints_TF_fork_head	-	no_errors	FOXA2	HGNC	ENSG00000125798	tier1	-	-	8	0	0.00	5	4	44.44
ENSG00000234978	0	genome.wustl.edu	37	1	142803302	142803302	+	RNA	DEL	C	C	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	142803302	142803302	C	-	DEL	ENSG00000234978	ENST00000423385	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	RP11-423O2.5	Clone_based_vega_gene	ENSG00000234978	tier1			114	1	0.87	89	8	8.25
MED12	0	genome.wustl.edu	37	X	70361169	70361170	+	In_Frame_Ins	INS	-	-	CAC			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	X	70361169	70361170	-	CAC	INS	MED12	ENST00000333646	human	ensembl	74_37	+1	known	in_frame_ins	c.6366_6367	p.2122in_frame_insH	1.000:1.000	NULL	pfam_Mediator_Med12_LCEWAV,pfam_Mediator_Med12_catenin-bd,pfam_Mediator_Med12	-	no_errors	MED12	HGNC	ENSG00000184634	tier1			59	0	0.00	24	4	14.29
TSPAN6	0	genome.wustl.edu	37	X	99890554	99890554	+	Splice_Site	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	X	99890554	99890554	C	A	SNP	TSPAN6	ENST00000373020	human	ensembl	74_37	-1	known	splice_site	c.276+1	e2+1	1.000	-	-	-	no_errors	TSPAN6	HGNC	ENSG00000000003	tier1	-	-	41	0	0.00	18	4	18.18
SLC8A2	0	genome.wustl.edu	37	19	47969326	47969326	+	Missense_Mutation	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	19	47969326	47969326	G	T	SNP	SLC8A2	ENST00000236877	human	ensembl	74_37	-1	known	missense	c.335	p.A112D	1.000	pfam_NaCa_Exmemb,tigrfam_Na_Ca_Ex	pfam_Calx_beta,pfam_NaCa_Exmemb,smart_Calx_beta,prints_Na_Ca_Ex,tigrfam_Na_Ca_Ex	-	no_errors	SLC8A2	HGNC	ENSG00000118160	tier1	-	-	54	0	0.00	22	3	12.00
GPR125	0	genome.wustl.edu	37	4	22404357	22404357	+	Silent	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	4	22404357	22404357	G	T	SNP	GPR125	ENST00000334304	human	ensembl	74_37	-1	known	silent	c.2298	p.T766	0.819	pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like	pfam_GPCR_2_secretin-like,pfam_GPS_dom,pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_GPCR_2_extracellular_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,pfscan_Ig-like_dom	-	no_errors	GPR125	HGNC	ENSG00000152990	tier1	-	-	51	0	0.00	32	4	11.11
WDFY4	0	genome.wustl.edu	37	10	49951225	49951225	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951225	49951225	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	silent	c.2091	p.V697	1.000	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	53	0	0.00	87	15	14.71
ENSG00000225411	0	genome.wustl.edu	37	9	68400511	68400511	+	RNA	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	9	68400511	68400511	G	A	SNP	ENSG00000225411	ENST00000417843	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.062	-	-	-	no_errors	RP11-764K9.1	Clone_based_vega_gene	ENSG00000225411	tier1	rs78515312	-	12	0	0.00	7	6	46.15
NDUFA4	0	genome.wustl.edu	37	7	10978463	10978463	+	Missense_Mutation	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	7	10978463	10978463	G	T	SNP	NDUFA4	ENST00000339600	human	ensembl	74_37	-1	known	missense	c.103	p.R35S	0.596	NULL	NULL	-	no_errors	NDUFA4	HGNC	ENSG00000189043	tier1	-	-	22	0	0.00	24	4	14.29
WDFY4	0	genome.wustl.edu	37	10	49951426	49951426	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951426	49951426	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	silent	c.2292	p.L764	0.014	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	42	0	0.00	87	20	18.69
MIR137HG	0	genome.wustl.edu	37	1	98511780	98511780	+	RNA	SNP	T	T	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	98511780	98511780	T	C	SNP	MIR137HG	ENST00000424528	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.007	-	-	-	no_errors	MIR137HG	HGNC	ENSG00000225206	tier1	-	-	35	0	0.00	9	10	52.63
WDFY4	0	genome.wustl.edu	37	10	49951403	49951403	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951403	49951403	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	missense	c.2269	p.P757S	1.000	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	42	0	0.00	74	16	17.78
SLC24A4	0	genome.wustl.edu	37	14	92923649	92923650	+	RNA	INS	-	-	ACACCAGG			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	14	92923649	92923650	-	ACACCAGG	INS	SLC24A4	ENST00000556739	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	SLC24A4	HGNC	ENSG00000140090	tier1			NA	NA	NA	NA	NA	NA
TCTN1	0	genome.wustl.edu	37	12	111065921	111065921	+	Silent	SNP	A	A	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	111065921	111065921	A	G	SNP	TCTN1	ENST00000397656	human	ensembl	74_37	+1	known	silent	c.537	p.P179	0.000	NULL	pfam_DUF1619	-	no_errors	TCTN1	HGNC	ENSG00000204852	tier1	-	-	53	0	0.00	19	25	56.82
LOC100507600	0	genome.wustl.edu	37	2	136579728	136579728	+	RNA	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	2	136579728	136579728	G	A	SNP	LOC100507600	ENST00000437007	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	AC011893.3	Clone_based_vega_gene	ENSG00000226806	tier1	-	-	28	0	0.00	19	7	26.92
MIR3177	0	genome.wustl.edu	37	16	1785034	1785034	+	RNA	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	1785034	1785034	C	T	SNP	MIR3177	ENST00000578255	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR3177	HGNC	ENSG00000265820	tier1	-	-	24	0	0.00	25	17	40.48
ACTA2	0	genome.wustl.edu	37	10	90701022	90701025	+	Frame_Shift_Del	DEL	TCTT	TCTT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TCTT	TCTT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	90701022	90701025	TCTT	-	DEL	ACTA2	ENST00000224784	human	ensembl	74_37	-1	known	frame_shift_del	c.580_577	p.K193fs	1.000:1.000:1.000:1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related,prints_Actin-related	-	no_errors	ACTA2	HGNC	ENSG00000107796	tier1			75	0	0.00	10	26	72.22
DLGAP4	0	genome.wustl.edu	37	20	35075162	35075162	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	20	35075162	35075162	G	A	SNP	DLGAP4	ENST00000339266	human	ensembl	74_37	+1	known	silent	c.1470	p.A490	0.001	NULL	pfam_GKAP	-	no_errors	DLGAP4	HGNC	ENSG00000080845	tier1	-	-	86	0	0.00	28	23	45.10
TRPM3	0	genome.wustl.edu	37	9	73391377	73391377	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	9	73391377	73391377	C	G	SNP	TRPM3	ENST00000396283	human	ensembl	74_37	-1	putative	missense	c.791	p.R264T	0.004	NULL	NULL	-	no_errors	TRPM3	HGNC	ENSG00000083067	tier1	-	-	57	0	0.00	25	23	47.92
ENSG00000200294	0	genome.wustl.edu	37	10	73940732	73940733	+	RNA	INS	-	-	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	73940732	73940733	-	T	INS	ENSG00000200294	ENST00000363424	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.371:0.371	-	-	-	no_errors	SNORA36	RFAM	ENSG00000200294	tier1			13	0	0.00	7	3	30.00
MAN1B1	0	genome.wustl.edu	37	9	139998199	139998275	+	RNA	DEL	TGCAGGTCGGTGGTGTTACATTCACACTGTTGCAGGTGTGCAGGTTGGTGTTACACACATTCACACTGTTGCAGGCT	TGCAGGTCGGTGGTGTTACATTCACACTGTTGCAGGTGTGCAGGTTGGTGTTACACACATTCACACTGTTGCAGGCT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TGCAGGTCGGTGGTGTTACATTCACACTGTTGCAGGTGTGCAGGTTGGTGTTACACACATTCACACTGTTGCAGGCT	TGCAGGTCGGTGGTGTTACATTCACACTGTTGCAGGTGTGCAGGTTGGTGTTACACACATTCACACTGTTGCAGGCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	9	139998199	139998275	TGCAGGTCGGTGGTGTTACATTCACACTGTTGCAGGTGTGCAGGTTGGTGTTACACACATTCACACTGTTGCAGGCT	-	DEL	MAN1B1	ENST00000540391	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.010:0.009:0.006:0.003:0.010:0.019:0.038:0.083:0.102:0.151:0.269:0.372:0.513:0.732:0.783:0.926:0.952:0.968:0.980:0.978:0.961:0.940:0.549:0.524:0.521:0.570:0.645:0.728:0.786:0.818:0.845:0.987:0.996:0.996:0.992:0.985:0.971:0.974:0.973:0.970:0.969:0.973:0.982:0.986:0.987:0.990:0.990:0.989:0.985:0.983:0.980:0.985:0.990:0.995:0.994:0.991:0.974:0.875:0.836:0.776:0.752:0.605:0.494:0.326:0.305:0.317:0.322:0.330:0.175:0.158:0.139:0.114:0.096:0.096:0.104:0.112:0.126	-	-	-	no_errors	MAN1B1	HGNC	ENSG00000177239	tier1			NA	NA	NA	NA	NA	NA
ANKRD6	0	genome.wustl.edu	37	6	90333179	90333179	+	Frame_Shift_Del	DEL	A	A	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	90333179	90333179	A	-	DEL	ANKRD6	ENST00000339746	human	ensembl	74_37	+1	known	frame_shift_del	c.948	p.E318fs	0.046	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD6	HGNC	ENSG00000135299	tier1			25	0	0.00	21	2	8.70
ACP1	0	genome.wustl.edu	37	2	272145	272145	+	Silent	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	2	272145	272145	C	A	SNP	ACP1	ENST00000272065	human	ensembl	74_37	+1	known	silent	c.226	p.R76	1.000	pfam_Ptyr_pPase_SF,superfamily_Ptyr_pPase_SF,smart_Ptyr_pPase_SF,prints_Tyr_Pase_low_mol_wt_mml	pfam_Ptyr_pPase_SF,superfamily_Ptyr_pPase_SF,smart_Ptyr_pPase_SF,prints_Tyr_Pase_low_mol_wt_mml,prints_Tyr_phospatase/Ars_reductase	-	no_errors	ACP1	HGNC	ENSG00000143727	tier1	-	-	111	0	0.00	36	4	10.00
GSN-AS1	0	genome.wustl.edu	37	9	124045974	124045974	+	RNA	SNP	T	T	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	9	124045974	124045974	T	C	SNP	GSN-AS1	ENST00000414544	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	GSN-AS1	HGNC	ENSG00000235865	tier1	rs78220606	-	20	0	0.00	9	5	35.71
ENSG00000221732	0	genome.wustl.edu	37	7	140280130	140280130	+	RNA	SNP	T	T	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	7	140280130	140280130	T	C	SNP	ENSG00000221732	ENST00000408805	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.057	-	-	-	no_errors	AC006452.1	Clone_based_ensembl_gene	ENSG00000221732	tier1	rs62485838	-	16	0	0.00	15	5	25.00
FRA10AC1	0	genome.wustl.edu	37	10	95433563	95433563	+	Missense_Mutation	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	95433563	95433563	G	T	SNP	FRA10AC1	ENST00000394100	human	ensembl	74_37	-1	known	missense	c.830	p.T277N	0.001	NULL	pfam_Folate-sensitive_fs_Fra10Ac1	-	no_errors	FRA10AC1	HGNC	ENSG00000148690	tier1	-	-	41	0	0.00	22	3	12.00
ENOSF1	0	genome.wustl.edu	37	18	690729	690730	+	Frame_Shift_Ins	INS	-	-	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	18	690729	690730	-	T	INS	ENOSF1	ENST00000581475	human	ensembl	74_37	-1	known	frame_shift_ins	c.440_439	p.T147fs	0.009:0.019	NULL	pfam_Mandelate_racemase_N	-	no_errors	ENOSF1	HGNC	ENSG00000132199	tier1			10	0	0.00	13	11	45.83
MSH3	0	genome.wustl.edu	37	5	79950742	79950750	+	In_Frame_Del	DEL	CCCCCAGCT	CCCCCAGCT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	CCCCCAGCT	CCCCCAGCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	5	79950742	79950750	CCCCCAGCT	-	DEL	MSH3	ENST00000265081	human	ensembl	74_37	+1	known	in_frame_del	c.196_204	p.PAP67in_frame_del	0.890:0.802:0.715:0.628:0.541:0.455:0.369:0.282:0.196	NULL	pfam_DNA_mismatch_repair_MutS_C,pfam_DNA_mismatch_repair_MutS_core,pfam_DNA_mmatch_repair_MutS_con_dom,pfam_DNA_mismatch_repair_MutS-lik_N,pfam_DNA_mismatch_repair_MutS_clamp,superfamily_DNA_mismatch_repair_MutS_core,superfamily_P-loop_NTPase,superfamily_DNA_mismatch_repair_MutS_N,superfamily_DNA_mmatch_repair_MutS_con_dom,smart_DNA_mismatch_repair_MutS_core,smart_DNA_mismatch_repair_MutS_C	-	no_errors	MSH3	HGNC	ENSG00000113318	tier1			NA	NA	NA	NA	NA	NA
ADAMTS18	0	genome.wustl.edu	37	16	77325184	77325184	+	Missense_Mutation	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	77325184	77325184	C	A	SNP	ADAMTS18	ENST00000282849	human	ensembl	74_37	-1	known	missense	c.3381	p.W1127C	1.000	superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_Peptidase_M12B_N,pfam_ADAM_spacer1,pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS18	HGNC	ENSG00000140873	tier1	-	-	72	0	0.00	11	21	65.62
DMD	0	genome.wustl.edu	37	X	32407656	32407656	+	Frame_Shift_Del	DEL	C	C	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	X	32407656	32407656	C	-	DEL	DMD	ENST00000357033	human	ensembl	74_37	-1	known	frame_shift_del	c.4480	p.E1494fs	0.965	smart_Spectrin/alpha-actinin,pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	DMD	HGNC	ENSG00000198947	tier1			56	0	0.00	9	2	18.18
KIAA1429	0	genome.wustl.edu	37	8	95547168	95547168	+	Missense_Mutation	SNP	A	A	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	95547168	95547168	A	T	SNP	KIAA1429	ENST00000297591	human	ensembl	74_37	-1	known	missense	c.383	p.V128E	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	KIAA1429	HGNC	ENSG00000164944	tier1	-	-	32	0	0.00	30	15	33.33
FBXO38	0	genome.wustl.edu	37	5	147806999	147806999	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	5	147806999	147806999	C	G	SNP	FBXO38	ENST00000340253	human	ensembl	74_37	+1	known	missense	c.2142	p.N714K	0.980	NULL	superfamily_F-box_dom	-	no_errors	FBXO38	HGNC	ENSG00000145868	tier1	-	-	10	0	0.00	10	6	37.50
HMGCLL1	0	genome.wustl.edu	37	6	55406543	55406543	+	Missense_Mutation	SNP	G	G	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	55406543	55406543	G	C	SNP	HMGCLL1	ENST00000398661	human	ensembl	74_37	-1	known	missense	c.371	p.S124C	1.000	pfam_PYR_CT,pfscan_PYR_CT	pfam_PYR_CT,pfscan_PYR_CT	-	no_errors	HMGCLL1	HGNC	ENSG00000146151	tier1	-	-	69	0	0.00	41	49	54.44
KNTC1	0	genome.wustl.edu	37	12	123070191	123070191	+	Silent	SNP	T	T	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	123070191	123070191	T	C	SNP	KNTC1	ENST00000333479	human	ensembl	74_37	+1	known	silent	c.3543	p.F1181	0.989	NULL	pfam_RZZ-complex_KNTC1/ROD_C,superfamily_Quino_amine_DH_bsu,superfamily_WD40_repeat_dom,superfamily_PAH	-	no_errors	KNTC1	HGNC	ENSG00000184445	tier1	-	-	92	0	0.00	56	35	38.46
KLC4	0	genome.wustl.edu	37	6	43041689	43041689	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	43041689	43041689	G	A	SNP	KLC4	ENST00000259708	human	ensembl	74_37	+1	known	missense	c.1849	p.A617T	0.909	NULL	pfam_Rabaptin_Rab5-bd_dom,pfam_TPR_1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom,prints_Kinesin_light	-	no_errors	KLC4	HGNC	ENSG00000137171	tier1	-	-	127	0	0.00	76	41	34.75
UCHL3	0	genome.wustl.edu	37	13	76178919	76178919	+	Frame_Shift_Del	DEL	T	T	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	13	76178919	76178919	T	-	DEL	UCHL3	ENST00000377595	human	ensembl	74_37	+1	known	frame_shift_del	c.565	p.P190fs	1.000	pfam_Peptidase_C12,prints_Peptidase_C12	pfam_Peptidase_C12,prints_Peptidase_C12	-	no_errors	UCHL3	HGNC	ENSG00000118939	tier1			30	0	0.00	7	2	22.22
WDR11	0	genome.wustl.edu	37	10	122648750	122648751	+	RNA	INS	-	-	TTTTGTTTTG			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	122648750	122648751	-	TTTTGTTTTG	INS	WDR11	ENST00000604509	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.024:0.006	-	-	-	no_errors	WDR11	HGNC	ENSG00000120008	tier1			NA	NA	NA	NA	NA	NA
GPRIN3	0	genome.wustl.edu	37	4	90168982	90168982	+	Missense_Mutation	SNP	G	G	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	4	90168982	90168982	G	C	SNP	GPRIN3	ENST00000333209	human	ensembl	74_37	-1	known	missense	c.2280	p.F760L	0.015	NULL	NULL	-	no_errors	GPRIN3	HGNC	ENSG00000185477	tier1	-	-	46	0	0.00	26	28	51.85
TM2D1	0	genome.wustl.edu	37	1	62190776	62190776	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	62190776	62190776	G	A	SNP	TM2D1	ENST00000371180	human	ensembl	74_37	-1	known	missense	c.203	p.P68L	0.004	NULL	pfam_TM2	-	no_errors	TM2D1	HGNC	ENSG00000162604	tier1	-	-	56	0	0.00	5	24	82.76
ARFGEF1	0	genome.wustl.edu	37	8	68188215	68188215	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	68188215	68188215	G	A	SNP	ARFGEF1	ENST00000262215	human	ensembl	74_37	-1	known	missense	c.1333	p.P445S	1.000	superfamily_ARM-type_fold	pfam_Sec7_dom,pfam_DUF1981_Sec7_assoc,superfamily_Sec7_dom,superfamily_ARM-type_fold,smart_Sec7_dom,pfscan_Sec7_dom	-	no_errors	ARFGEF1	HGNC	ENSG00000066777	tier1	-	-	58	0	0.00	54	8	12.90
MRGPRX3	0	genome.wustl.edu	37	11	18159001	18159001	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	18159001	18159001	G	A	SNP	MRGPRX3	ENST00000396275	human	ensembl	74_37	+1	known	silent	c.252	p.P84	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	-	no_errors	MRGPRX3	HGNC	ENSG00000179826	tier1	rs148328055	-	57	0	0.00	12	25	67.57
KDM6B	0	genome.wustl.edu	37	17	7751859	7751864	+	In_Frame_Del	DEL	CACCAC	CACCAC	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	CACCAC	CACCAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	17	7751859	7751864	CACCAC	-	DEL	KDM6B	ENST00000254846	human	ensembl	74_37	+1	known	in_frame_del	c.2253_2258	p.TT755in_frame_del	0.000:0.006:0.963:0.964:0.935:0.971	NULL	pfam_JmjC_dom,smart_JmjC_dom,pfscan_JmjC_dom	-	no_errors	KDM6B	HGNC	ENSG00000132510	tier1			NA	NA	NA	NA	NA	NA
GATC	0	genome.wustl.edu	37	12	120884315	120884324	+	Frame_Shift_Del	DEL	GGGCCCCTCT	GGGCCCCTCT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	GGGCCCCTCT	GGGCCCCTCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	120884315	120884324	GGGCCCCTCT	-	DEL	GATC	ENST00000551765	human	ensembl	74_37	+1	known	frame_shift_del	c.32_41	p.P13fs	0.002:0.002:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000	NULL	pfam_Asp/Glu-ADT_csu,tigrfam_Asp/Glu-ADT_csu	-	no_errors	GATC	HGNC	ENSG00000257218	tier1			NA	NA	NA	NA	NA	NA
SP100	0	genome.wustl.edu	37	2	231334505	231334508	+	Frame_Shift_Del	DEL	AAAG	AAAG	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	AAAG	AAAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	2	231334505	231334508	AAAG	-	DEL	SP100	ENST00000341950	human	ensembl	74_37	+1	known	frame_shift_del	c.1359_1362	p.K454fs	0.006:0.006:0.010:0.013	NULL	pfam_Sp100	-	no_errors	SP100	HGNC	ENSG00000067066	tier1			10	0	0.00	16	11	40.74
ENSG00000223697	0	genome.wustl.edu	37	8	133854715	133854715	+	RNA	DEL	T	T	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	133854715	133854715	T	-	DEL	ENSG00000223697	ENST00000608375	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	AF230666.2	Clone_based_vega_gene	ENSG00000223697	tier1			20	0	0.00	16	3	15.79
HSD17B12	0	genome.wustl.edu	37	11	43819959	43819959	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	43819959	43819959	C	T	SNP	HSD17B12	ENST00000278353	human	ensembl	74_37	+1	known	missense	c.373	p.L125F	0.999	pfam_DH_sc/Rdtase_SDR,prints_Glc/ribitol_DH,prints_DH_sc/Rdtase_SDR	pfam_DH_sc/Rdtase_SDR,prints_Glc/ribitol_DH,prints_DH_sc/Rdtase_SDR	-	no_errors	HSD17B12	HGNC	ENSG00000149084	tier1	-	-	47	0	0.00	18	13	41.94
WDFY4	0	genome.wustl.edu	37	10	49951504	49951504	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951504	49951504	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	silent	c.2370	p.T790	0.000	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	39	0	0.00	60	18	23.08
GATC	0	genome.wustl.edu	37	12	120884319	120884319	+	Silent	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	120884319	120884319	C	G	SNP	GATC	ENST00000551765	human	ensembl	74_37	+1	known	silent	c.36	p.A12	0.000	NULL	pfam_Asp/Glu-ADT_csu,tigrfam_Asp/Glu-ADT_csu	-	no_errors	GATC	HGNC	ENSG00000257218	tier1	-	-	110	0	0.00	62	20	24.39
GLI1	0	genome.wustl.edu	37	12	57864284	57864284	+	Nonsense_Mutation	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	57864284	57864284	C	A	SNP	GLI1	ENST00000228682	human	ensembl	74_37	+1	known	nonsense	c.1761	p.Y587*	1.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	GLI1	HGNC	ENSG00000111087	tier1	-	-	60	0	0.00	34	16	32.00
CDH15	0	genome.wustl.edu	37	16	89249976	89249976	+	Frame_Shift_Del	DEL	C	C	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	89249976	89249976	C	-	DEL	CDH15	ENST00000289746	human	ensembl	74_37	+1	known	frame_shift_del	c.378	p.L127fs	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH15	HGNC	ENSG00000129910	tier1			78	0	0.00	17	2	10.53
HAVCR1	0	genome.wustl.edu	37	5	156479558	156479572	+	In_Frame_Del	DEL	TTGGAACAGTCGTCA	TTGGAACAGTCGTCA	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TTGGAACAGTCGTCA	TTGGAACAGTCGTCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	5	156479558	156479572	TTGGAACAGTCGTCA	-	DEL	HAVCR1	ENST00000425854	human	ensembl	74_37	-1	known	in_frame_del	c.487_473	p.MTTVP158in_frame_del	0.011:0.025:0.031:0.006:0.001:0.001:0.002:0.007:0.020:0.018:0.001:0.000:0.000:0.000:0.000	NULL	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	HAVCR1	HGNC	ENSG00000113249	tier1			NA	NA	NA	NA	NA	NA
GATC	0	genome.wustl.edu	37	12	120884322	120884331	+	Frame_Shift_Del	DEL	TCTGGGCGGG	TCTGGGCGGG	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TCTGGGCGGG	TCTGGGCGGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	120884322	120884331	TCTGGGCGGG	-	DEL	GATC	ENST00000551765	human	ensembl	74_37	+1	known	frame_shift_del	c.39_48	p.L14fs	0.000:0.000:0.000:0.001:0.000:0.000:0.000:0.000:0.000:0.000	NULL	pfam_Asp/Glu-ADT_csu,tigrfam_Asp/Glu-ADT_csu	-	no_errors	GATC	HGNC	ENSG00000257218	tier1			NA	NA	NA	NA	NA	NA
OR10S1	0	genome.wustl.edu	37	11	123847411	123847411	+	Missense_Mutation	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	123847411	123847411	G	T	SNP	OR10S1	ENST00000531945	human	ensembl	74_37	-1	known	missense	c.988	p.P330T	0.014	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10S1	HGNC	ENSG00000196248	tier1	-	-	16	0	0.00	17	7	29.17
ACTA2	0	genome.wustl.edu	37	10	90701026	90701026	+	Missense_Mutation	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	90701026	90701026	C	A	SNP	ACTA2	ENST00000224784	human	ensembl	74_37	-1	known	missense	c.576	p.M192I	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related,prints_Actin-related	-	no_errors	ACTA2	HGNC	ENSG00000107796	tier1	-	-	73	0	0.00	9	30	76.92
IL21R-AS1	0	genome.wustl.edu	37	16	27459684	27459684	+	RNA	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	27459684	27459684	G	T	SNP	IL21R-AS1	ENST00000563191	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	IL21R-AS1	HGNC	ENSG00000259954	tier1	-	-	13	0	0.00	5	8	61.54
ANP32E	0	genome.wustl.edu	37	1	150199040	150199045	+	In_Frame_Del	DEL	TCCTCT	TCCTCT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TCCTCT	TCCTCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	150199040	150199045	TCCTCT	-	DEL	ANP32E	ENST00000314136	human	ensembl	74_37	-1	known	in_frame_del	c.581_576	p.EE193in_frame_del	0.001:0.006:0.000:0.058:0.106:0.091	NULL	pfam_Leu-rich_rpt	-	no_errors	ANP32E	HGNC	ENSG00000143401	tier1			NA	NA	NA	NA	NA	NA
UBAC2	0	genome.wustl.edu	37	13	100038221	100038221	+	RNA	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	13	100038221	100038221	C	G	SNP	UBAC2	ENST00000460562	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.685	-	-	-	no_errors	UBAC2	HGNC	ENSG00000134882	tier1	-	-	12	0	0.00	3	8	72.73
SLC17A4	0	genome.wustl.edu	37	6	25771211	25771211	+	Missense_Mutation	SNP	T	T	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	25771211	25771211	T	A	SNP	SLC17A4	ENST00000377905	human	ensembl	74_37	+1	known	missense	c.677	p.I226K	0.004	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A4	HGNC	ENSG00000146039	tier1	-	-	128	0	0.00	6	43	87.76
PREP	0	genome.wustl.edu	37	6	105726234	105726234	+	Missense_Mutation	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	105726234	105726234	G	T	SNP	PREP	ENST00000369110	human	ensembl	74_37	-1	known	missense	c.1918	p.H640N	1.000	pfam_Peptidase_S9,prints_Peptidase_S9A	pfam_Pept_S9A_N,pfam_Peptidase_S9,prints_Peptidase_S9A	-	no_errors	PREP	HGNC	ENSG00000085377	tier1	-	-	36	0	0.00	46	4	8.00
PLCZ1	0	genome.wustl.edu	37	12	18854541	18854549	+	In_Frame_Del	DEL	TCCTCCTCC	TCCTCCTCC	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TCCTCCTCC	TCCTCCTCC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	18854541	18854549	TCCTCCTCC	-	DEL	PLCZ1	ENST00000538330	human	ensembl	74_37	-1	putative	in_frame_del	c.257_249	p.EEE83in_frame_del	0.019:0.025:0.029:0.032:0.034:0.034:0.032:0.029:0.024	superfamily_PLC-like_Pdiesterase_TIM-brl	pfam_PLipase_C_Pinositol-sp_Y,pfam_C2_dom,superfamily_PLC-like_Pdiesterase_TIM-brl,superfamily_C2_dom,smart_PLipase_C_Pinositol-sp_Y,smart_C2_dom,pfscan_C2_dom,pfscan_PLipase_C_PInositol-sp_X_dom,pfscan_PLipase_C_Pinositol-sp_Y,prints_Pinositol_PLipase_C	-	no_errors	PLCZ1	HGNC	ENSG00000139151	tier1			NA	NA	NA	NA	NA	NA
