Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
ACLY	0	genome.wustl.edu	37	17	40068795	40068798	+	Frame_Shift_Del	DEL	TCTG	TCTG	-			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	TCTG	TCTG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	17	40068795	40068798	TCTG	-	DEL	ACLY	ENST00000352035	human	ensembl	69_37n	-1	known	frame_shift_del	c.160	p.N54fs	0.997	pfam_ATP-grasp_succ-CoA_synth-type,pirsf_ATP-citrate_synthase	pfam_Citrate_synthase-like,pfam_CoA_ligase,pfam_CoA-bd,pfam_ATP-grasp_succ-CoA_synth-type,superfamily_Citrate_synthase-like_core,superfamily_Succinyl-CoA_synth-like,smart_CoA-bd,pirsf_ATP-citrate_synthase	-	no_errors	ACLY	HGNC	ENSG00000131473	87	0	0.00	66	35	34.65	-	-	-
ACVR1B	0	genome.wustl.edu	37	12	52370172	52370172	+	Silent	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	12	52370172	52370172	C	T	SNP	ACVR1B	ENST00000257963	human	ensembl	69_37n	+1	known	silent	c.393	p.I131	0.994	NULL	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_TGF_beta_rcpt_GS,pfam_Activin_rcpt,superfamily_Kinase-like_dom,smart_TGF_beta_rcpt_GS,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	-	no_errors	ACVR1B	HGNC	ENSG00000135503	122	1	0.81	92	54	36.99	-	-	-
AHCY	0	genome.wustl.edu	37	20	32878392	32878392	+	Silent	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	20	32878392	32878392	G	A	SNP	AHCY	ENST00000217426	human	ensembl	69_37n	-1	known	silent	c.819	p.V273	0.999	pfam_Adenosylhomocysteinase,pfam_Ado_hCys_hydrolase_NAD-bd,pfam_D-isomer_2_OHA_DH_NAD-bd,pfam_IlvN,pirsf_Adenosylhomocysteinase,tigrfam_Adenosylhomocysteinase	pfam_Adenosylhomocysteinase,pfam_Ado_hCys_hydrolase_NAD-bd,pfam_D-isomer_2_OHA_DH_NAD-bd,pfam_IlvN,pirsf_Adenosylhomocysteinase,tigrfam_Adenosylhomocysteinase	-	no_errors	AHCY	HGNC	ENSG00000101444	167	0	0.00	138	83	37.56	-	-	-
AKAP9	0	genome.wustl.edu	37	7	91652213	91652213	+	Silent	SNP	C	C	G			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	7	91652213	91652213	C	G	SNP	AKAP9	ENST00000359028	human	ensembl	69_37n	+1	known	silent	c.4074	p.L1358	0.000	NULL	pfam_PACT_domain,superfamily_Prefoldin,superfamily_YbaB-like	-	no_errors	AKAP9	HGNC	ENSG00000127914	179	0	0.00	101	44	30.34	-	-	-
ALPK2	0	genome.wustl.edu	37	18	56191061	56191061	+	Missense_Mutation	SNP	A	A	C			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	18	56191061	56191061	A	C	SNP	ALPK2	ENST00000361673	human	ensembl	69_37n	-1	known	missense	c.5642	p.L1881R	0.993	superfamily_Kinase-like_dom	pfam_MHCK_EF2_kinase,pfam_Ig_I-set,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_MHCK_EF2_kinase,pfscan_MHCK_EF2_kinase,pfscan_Ig-like	-	no_errors	ALPK2	HGNC	ENSG00000198796	205	0	0.00	44	47	51.09	-	-	-
AP1B1	0	genome.wustl.edu	37	22	29727482	29727482	+	Missense_Mutation	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	22	29727482	29727482	G	A	SNP	AP1B1	ENST00000357586	human	ensembl	69_37n	-1	known	missense	c.2480	p.T827I	1.000	superfamily_Coatomer/clathrin_app_Ig-like	pfam_Clathrin/coatomer_adapt-like_N,pfam_B-adaptin_app_sub_C,pfam_HEAT,pfam_Clathrin_a/b/g-adaptin_app_Ig,superfamily_ARM-type_fold,superfamily_Coatomer/calthrin_app_sub_C,superfamily_Coatomer/clathrin_app_Ig-like,smart_Armadillo,smart_Clathrin_a/b/g-adaptin_app_Ig,pirsf_AP_complex_bsu	-	no_errors	AP1B1	HGNC	ENSG00000100280	89	0	0.00	62	12	16.22	-	-	-
BCL6B	0	genome.wustl.edu	37	17	6929853	6929853	+	Missense_Mutation	SNP	G	G	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	17	6929853	6929853	G	T	SNP	BCL6B	ENST00000293805	human	ensembl	69_37n	+1	known	missense	c.967	p.D323Y	0.261	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	BCL6B	HGNC	ENSG00000161940	60	0	0.00	47	7	12.96	-	-	-
BNC1	0	genome.wustl.edu	37	15	83932783	83932783	+	Missense_Mutation	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	15	83932783	83932783	G	A	SNP	BNC1	ENST00000345382	human	ensembl	69_37n	-1	known	missense	c.1220	p.A407V	1.000	smart_Znf_C2H2-like	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	BNC1	HGNC	ENSG00000169594	145	0	0.00	52	38	41.76	-	-	-
BRCA2	0	genome.wustl.edu	37	13	32912296	32912298	+	In_Frame_Del	DEL	TGT	TGT	-			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	TGT	TGT					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	13	32912296	32912298	TGT	-	DEL	BRCA2	ENST00000380152	human	ensembl	69_37n	+1	known	in_frame_del	c.3804_3806	p.V1270in_frame_del	0.207:0.005:0.021	pirsf_DNA_recomb/repair_BRCA2	pfam_DNA_recomb/repair_BRCA2_hlx,pfam_BRCA2_repeat,pfam_BRCA2_OB_3,pfam_BRCA2_OB_1,pfam_Tower,superfamily_DNA_recomb/repair_BRCA2_hlx,superfamily_NA-bd_OB-fold-like,pirsf_DNA_recomb/repair_BRCA2,pfscan_BRCA2_repeat	-	no_errors	BRCA2	HGNC	ENSG00000139618	81	0	0.00	20	25	55.56	-	-	-
CECR2	0	genome.wustl.edu	37	22	18022046	18022047	+	Frame_Shift_Ins	INS	-	-	G			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	22	18022046	18022047	-	G	INS	CECR2	ENST00000400573	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.2148_2149	p.A718fs	0.066:0.122	NULL	pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,pfscan_Bromodomain,prints_Bromodomain	-	no_errors	CECR2	HGNC	ENSG00000099954	47	0	0.00	39	5	11.36	-	-	-
DISP1	0	genome.wustl.edu	37	1	223177609	223177609	+	Missense_Mutation	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	1	223177609	223177609	C	T	SNP	DISP1	ENST00000284476	human	ensembl	69_37n	+1	known	missense	c.2870	p.S957L	0.034	NULL	pfam_Patched,pfam_MMPL-typ,pfscan_SSD	-	no_errors	DISP1	HGNC	ENSG00000154309	94	0	0.00	60	35	36.84	-	-	-
FLNA	0	genome.wustl.edu	37	X	153593204	153593204	+	Missense_Mutation	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	X	153593204	153593204	C	T	SNP	FLNA	ENST00000369850	human	ensembl	69_37n	-1	known	missense	c.1813	p.D605N	0.993	pfam_Filamin/ABP280_repeat-like,superfamily_Ig_E-set,smart_Filamin,pfscan_Filamin/ABP280_repeat-like	pfam_Filamin/ABP280_repeat-like,pfam_CH-domain,superfamily_CH-domain,superfamily_Ig_E-set,smart_CH-domain,smart_Filamin,pfscan_CH-domain,pfscan_Filamin/ABP280_repeat-like	-	no_errors	FLNA	HGNC	ENSG00000196924	23	0	0.00	21	9	30.00	-	-	-
FYCO1	0	genome.wustl.edu	37	3	46008081	46008081	+	Silent	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	3	46008081	46008081	C	T	SNP	FYCO1	ENST00000535325	human	ensembl	69_37n	-1	known	silent	c.2745	p.L915	0.986	NULL	pfam_Znf_FYVE,pfam_Run,superfamily_GOLD,superfamily_Znf_FYVE_PHD,superfamily_Prefoldin,superfamily_tRNA-bd_arm,smart_Znf_FYVE,pfscan_GOLD,pfscan_Run,pfscan_Znf_FYVE-rel	-	no_errors	FYCO1	HGNC	ENSG00000163820	55	0	0.00	28	4	12.50	-	-	-
GBP6	0	genome.wustl.edu	37	1	89849788	89849788	+	Silent	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	1	89849788	89849788	G	A	SNP	GBP6	ENST00000370456	human	ensembl	69_37n	+1	known	silent	c.1605	p.Q535	0.015	pfam_Guanylate-bd_C,superfamily_Guanylate-bd_C	pfam_Guanylate-bd_N,pfam_Guanylate-bd_C,superfamily_Guanylate-bd_C	-	no_errors	GBP6	HGNC	ENSG00000183347	153	0	0.00	66	13	16.46	-	-	-
GPR125	0	genome.wustl.edu	37	4	22440036	22440036	+	Missense_Mutation	SNP	T	T	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	4	22440036	22440036	T	A	SNP	GPR125	ENST00000334304	human	ensembl	69_37n	-1	known	missense	c.928	p.T310S	1.000	pfam_Ig_I-set,smart_Ig_sub,pfscan_Ig-like	pfam_GPCR_2_secretin-like,pfam_GPS_dom,pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_GPCR_2_extracellular_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,pfscan_Ig-like	-	no_errors	GPR125	HGNC	ENSG00000152990	223	0	0.00	46	18	28.12	-	-	-
HERC1	0	genome.wustl.edu	37	15	63958635	63958635	+	Missense_Mutation	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	15	63958635	63958635	G	A	SNP	HERC1	ENST00000443617	human	ensembl	69_37n	-1	known	missense	c.8243	p.P2748L	1.000	superfamily_UBA-like	pfam_Reg_chr_condens,pfam_HECT,pfam_WD40_repeat,pfam_SPRY_rcpt,superfamily_Reg_csome_cond/b-lactamase_inh,superfamily_HECT,superfamily_WD40_repeat_dom,superfamily_ConA-like_lec_gl,superfamily_UBA-like,superfamily_ARM-type_fold,smart_SPla/RYanodine_receptor_subgr,smart_WD40_repeat,smart_HECT,pfscan_B30.2/SPRY,pfscan_HECT,pfscan_Reg_chr_condens,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_Reg_chr_condens	-	no_errors	HERC1	HGNC	ENSG00000103657	156	0	0.00	61	35	36.46	-	-	-
HERC2P4	0	genome.wustl.edu	37	16	32163575	32163575	+	RNA	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	16	32163575	32163575	G	A	SNP	HERC2P4	ENST00000563904	human	ensembl	69_37n	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	HERC2P4	HGNC	ENSG00000230267	42	0	0.00	13	19	59.38	-	-	-
IL27RA	0	genome.wustl.edu	37	19	14143204	14143204	+	Missense_Mutation	SNP	C	C	G			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	19	14143204	14143204	C	G	SNP	IL27RA	ENST00000263379	human	ensembl	69_37n	+1	known	missense	c.107	p.A36G	0.000	NULL	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	IL27RA	HGNC	ENSG00000104998	52	0	0.00	21	13	38.24	-	-	-
MED23	0	genome.wustl.edu	37	6	131908938	131908938	+	Nonsense_Mutation	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	6	131908938	131908938	G	A	SNP	MED23	ENST00000368058	human	ensembl	69_37n	-1	known	nonsense	c.4006	p.R1336*	1.000	NULL	pfam_Mediator_Med23	-	no_errors	MED23	HGNC	ENSG00000112282	179	1	0.56	82	22	21.15	-	-	-
MIR548C	0	genome.wustl.edu	37	12	65016369	65016370	+	RNA	INS	-	-	C			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	12	65016369	65016370	-	C	INS	MIR548C	ENST00000384815	human	ensembl	69_37n	+1	known	rna	NULL	NULL	0.001:0.000	-	-	-	no_errors	MIR548C	HGNC	ENSG00000207546	23	0	0.00	4	3	42.86	-	-	-
OR10A3	0	genome.wustl.edu	37	11	7960264	7960264	+	Silent	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	11	7960264	7960264	G	A	SNP	OR10A3	ENST00000360759	human	ensembl	69_37n	-1	known	silent	c.804	p.P268	0.800	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn	-	no_errors	OR10A3	HGNC	ENSG00000170683	286	2	0.69	221	52	18.98	-	-	-
PDZD2	0	genome.wustl.edu	37	5	32088972	32088972	+	Silent	SNP	T	T	C			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	5	32088972	32088972	T	C	SNP	PDZD2	ENST00000282493	human	ensembl	69_37n	+1	known	silent	c.5418	p.N1806	0.007	NULL	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	PDZD2	HGNC	ENSG00000133401	143	0	0.00	82	49	37.40	-	-	-
PIK3CA	0	genome.wustl.edu	37	3	178936091	178936091	+	Missense_Mutation	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	3	178936091	178936091	G	A	SNP	PIK3CA	ENST00000263967	human	ensembl	69_37n	+1	known	missense	c.1633	p.E545K	1.000	pfam_PInositide-3_kin_accessory_dom,superfamily_ARM-type_fold,smart_PInositide-3_kin_accessory_dom	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CA	HGNC	ENSG00000121879	133	0	0.00	53	35	39.77	-	-	-
PPAN-P2RY11	0	genome.wustl.edu	37	19	10224677	10224677	+	Missense_Mutation	SNP	G	G	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	19	10224677	10224677	G	T	SNP	PPAN-P2RY11	ENST00000393796	human	ensembl	69_37n	+1	known	missense	c.1648	p.G550C	1.000	pfam_7TM_GPCR_Rhodpsn,prints_P2_purnocptor,prints_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam	pfam_Brix,pfam_7TM_GPCR_Rhodpsn,superfamily_Anticodon-bd,smart_Brix,prints_P2_purnocptor,prints_7TM_GPCR_Rhodpsn,pfscan_Brix,pfscan_GPCR_Rhodpsn_supfam	-	no_errors	PPAN-P2RY11	HGNC	ENSG00000243207	26	0	0.00	10	14	58.33	-	-	-
PRAMEF7	0	genome.wustl.edu	37	1	12980232	12980232	+	Silent	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	1	12980232	12980232	G	A	SNP	PRAMEF7	ENST00000330881	human	ensembl	69_37n	+1	known	silent	c.1424	p.*475	0.000	NULL	NULL	-	no_errors	PRAMEF7	HGNC	ENSG00000204510	39	0	0.00	37	6	13.95	-	-	-
PTGDR	0	genome.wustl.edu	37	14	52741544	52741544	+	Silent	SNP	G	G	C			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	14	52741544	52741544	G	C	SNP	PTGDR	ENST00000306051	human	ensembl	69_37n	+1	known	silent	c.942	p.V314	0.998	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Pglndn_D_rcpt	pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Pglndn_D_rcpt,prints_Prostanoid_rcpt	-	no_errors	PTGDR	HGNC	ENSG00000168229	114	0	0.00	58	35	37.63	-	-	-
RAPGEF4	0	genome.wustl.edu	37	2	173900899	173900900	+	Frame_Shift_Ins	INS	-	-	G			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	2	173900899	173900900	-	G	INS	RAPGEF4	ENST00000397081	human	ensembl	69_37n	+1	known	frame_shift_ins	c.2747_2748	p.E917fs	1.000:1.000	pfam_RasGRF_CDC25,superfamily_Ras_GEF_dom,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25	pfam_RasGRF_CDC25,pfam_cNMP-bd_dom,pfam_DEP_dom,pfam_Ras-like_Gua-exchang_fac_N,pfam_Ras-assoc,superfamily_Ras_GEF_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,smart_DEP_dom,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_cNMP-bd_dom,pfscan_DEP_dom,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N,prints_cAMP/cGMP_kin	-	no_errors	RAPGEF4	HGNC	ENSG00000091428	274	0	0.00	193	24	11.06	-	-	-
RC3H1	0	genome.wustl.edu	37	1	173939653	173939653	+	Missense_Mutation	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	1	173939653	173939653	C	T	SNP	RC3H1	ENST00000258349	human	ensembl	69_37n	-1	known	missense	c.1324	p.E442K	1.000	NULL	pfam_Znf_CCCH,smart_Znf_RING,smart_Znf_CCCH,pfscan_Znf_RING	-	no_errors	RC3H1	HGNC	ENSG00000135870	228	0	0.00	103	135	56.72	-	-	-
SH3PXD2A	0	genome.wustl.edu	37	10	105363029	105363029	+	Nonsense_Mutation	SNP	G	G	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	10	105363029	105363029	G	T	SNP	SH3PXD2A	ENST00000369774	human	ensembl	69_37n	-1	known	nonsense	c.1946	p.S649*	0.144	NULL	pfam_SH3_domain,pfam_SH3_2,pfam_Phox,superfamily_Phox,superfamily_SH3_domain,smart_Phox,smart_SH3_domain,pfscan_Phox,pfscan_SH3_domain	-	no_errors	SH3PXD2A	HGNC	ENSG00000107957	74	0	0.00	72	8	10.00	-	-	-
SPEG	0	genome.wustl.edu	37	2	220354586	220354586	+	Missense_Mutation	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	2	220354586	220354586	C	T	SNP	SPEG	ENST00000312358	human	ensembl	69_37n	+1	novel	missense	c.8846	p.S2949F	0.990	NULL	pfam_Ig_I-set,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_cat_dom,pfscan_Ig-like	-	no_errors	SPEG	HGNC	ENSG00000072195	17	0	0.00	4	5	55.56	-	-	-
TBC1D3B	0	genome.wustl.edu	37	17	34493597	34493597	+	Silent	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	17	34493597	34493597	C	T	SNP	TBC1D3B	ENST00000398801	human	ensembl	69_37n	-1	known	silent	c.1428	p.Q476	0.127	NULL	pfam_Rab-GTPase-TBC_dom,superfamily_Rab-GTPase-TBC_dom,smart_Rab-GTPase-TBC_dom,pfscan_Rab-GTPase-TBC_dom	-	no_errors	TBC1D3B	HGNC	ENSG00000224226	24	0	0.00	34	14	29.17	-	-	-
TRPC3	0	genome.wustl.edu	37	4	122853579	122853579	+	Silent	SNP	G	G	A			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	4	122853579	122853579	G	A	SNP	TRPC3	ENST00000379645	human	ensembl	69_37n	-1	known	silent	c.834	p.H278	0.989	pfam_TRP_dom,tigrfam_TRP_channel	pfam_Ion_trans_dom,pfam_TRP_dom,pfam_PKD1_2_channel,superfamily_Ankyrin_rpt-contain_dom,superfamily_ARM-type_fold,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_TRPC3_channel,prints_TRPC_channel,tigrfam_TRP_channel	-	no_errors	TRPC3	HGNC	ENSG00000138741	34	0	0.00	28	8	22.22	-	-	-
UGT2B7	0	genome.wustl.edu	37	4	69973882	69973882	+	Silent	SNP	C	C	T			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	4	69973882	69973882	C	T	SNP	UGT2B7	ENST00000305231	human	ensembl	69_37n	+1	known	silent	c.1152	p.I384	1.000	pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C	pfam_UDP_glucos_trans,pfam_Glyco_trans_28_C	-	no_errors	UGT2B7	HGNC	ENSG00000171234	283	0	0.00	146	26	15.12	-	-	-
ZSCAN5C	0	genome.wustl.edu	37	19	56720191	56720191	+	Silent	SNP	A	A	G			TCGA-A8-A08B-01A-11W-A019-09	TCGA-A8-A08B-10A-01W-A021-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	267a951b-29b7-4849-9ea7-d2205838fcc7	ae64a42d-572d-46be-8392-f04ec3ab5bf9	19	56720191	56720191	A	G	SNP	ZSCAN5C	ENST00000376267	human	ensembl	69_37n	+1	known	silent	c.1113	p.L371	0.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZSCAN5C	HGNC	ENSG00000204532	67	0	0.00	77	9	10.47	-	-	-
